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https://www.readbyqxmd.com/read/28822837/delayed-pain-decrease-following-m1-tdcs-in-spinal-cord-injury-a-randomized-controlled-clinical-trial
#1
Aurore Thibaut, Sandra Carvalho, Leslie Morse, Ross Zafonte, Felipe Fregni
Despite some encouraging findings for the treatment of neuropathic pain in patients with spinal cord injury (SCI), transcranial direct current stimulation (tDCS) directed to the primary motor cortex (M1) has faced some mixed results. Prior to translating this technology to clinical care, consistent results and durable effects need to be found. We, therefore, aimed to assess the direct and long-term effects of tDCS on pain following SCI. We performed a two-phase randomized sham-controlled clinical trial where patients received 5days of tDCS followed by at 3-month follow-up period (Phase I); then, Phase II consisted of 10days of tDCS with an 8-week follow-up period...
August 16, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28822654/polarity-independent-effects-of-tdcs-on-paired-associative-stimulation-induced-plasticity
#2
Hanna Faber, Alexander Opitz, Florian Müller-Dahlhaus, Ulf Ziemann
BACKGROUND: Transcranial direct current stimulation (tDCS) can polarize the cortex of the human brain. OBJECTIVE/HYPOTHESIS: We sought to verify the hypothesis that posterior-anterior (PA) but not anterior-posterior (AP) tDCS of primary motor cortex (M1) produces cooperative effects with corticospinal plasticity induced by paired associative stimulation of the supplementary motor area (SMA) to M1 projection (PASSMA→M1) in a highly controlled experimental design...
July 27, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28822321/neurostimulation-techniques-in-the-treatment-of-cocaine-dependence-a-review-of-the-literature
#3
REVIEW
Fady Rachid
OBJECTIVE: Cocaine use disorder is a very common condition that represents a substantial public health problem, and no effective pharmacological or psychological therapies have been identified to date. Urgent therapeutic alternatives are therefore needed such as neurostimulation techniques. The purpose of this review is to describe and discuss studies that have evaluated the safety and efficacy of these techniques for the treatment of cocaine dependence. METHODS: The electronic literature on repetitive transcranial magnetic stimulation, theta-burst stimulation, deep transcranial magnetic stimulation, transcranial direct current stimulation, magnetic seizure therapy, electroconvulsive therapy, cranial electro-stimulation, and deep brain stimulation in the treatment of cocaine addiction were reviewed...
August 10, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28821991/transcranial-doppler-in-autonomic-testing-standards-and-clinical-applications
#4
REVIEW
Lucy Norcliffe-Kaufmann, Brahyan Galindo-Mendez, Ana-Lucia Garcia-Guarniz, Estibaliz Villarreal-Vitorica, Vera Novak
When cerebral blood flow falls below a critical limit, syncope occurs and, if prolonged, ischemia leads to neuronal death. The cerebral circulation has its own complex finely tuned autoregulatory mechanisms to ensure blood supply to the brain can meet the high metabolic demands of the underlying neuronal tissue. This involves the interplay between myogenic and metabolic mechanisms, input from noradrenergic and cholinergic neurons, and the release of vasoactive substrates, including adenosine from astrocytes and nitric oxide from the endothelium...
August 18, 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/28821677/disruption-of-m1-activity-during-performance-plateau-impairs-consolidation-of-motor-memories
#5
Raphaël Hamel, Maxime Trempe, Pierre-Michel Bernier
Upon exposure to a new sensorimotor relationship, motor behaviors iteratively change early in adaptation, but eventually stabilize as adaptation proceeds. Behavioral work suggests that motor memory consolidation is initiated upon the attainment of asymptotic levels of performance. Separate lines of evidence point to a critical role of the primary motor cortex (M1) in consolidation. However, a causal relationship between M1 activity during asymptote and consolidation has yet to be demonstrated. The present study investigated this issue in male and female participants using single-pulse transcranial magnetic stimulation (TMS) to interfere with post-movement activity in M1 in two behavioral phases of a ramp-and-hold visuomotor adaptation paradigm...
August 18, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28821470/design-of-the-drepagreffe-trial-a-prospective-controlled-multicenter-study-evaluating-the-benefit-of-genoidentical-hematopoietic-stem-cell-transplantation-over-chronic-transfusion-in-sickle-cell-anemia-children-detected-to-be-at-risk-of-stroke-by-transcranial
#6
Sylvie Chevret, Suzanne Verlhac, Elisabeth Ducros-Miralles, Jean-Hugues Dalle, Regis Peffault de Latour, Mariane de Montalembert, Malika Benkerrou, Corinne Pondarré, Isabelle Thuret, Corinne Guitton, Emmanuelle Lesprit, Maryse Etienne-Julan, Gisèle Elana, Jean-Pierre Vannier, Patrick Lutz, Bénédicte Neven, Claire Galambrun, Catherine Paillard, Camille Runel, Charlotte Jubert, Cécile Arnaud, Annie Kamdem, Valentine Brousse, Florence Missud, Marie Petras, Lydia Doumdo-Divialle, Claire Berger, Françoise Fréard, Olivier Taieb, Elise Drain, Monique Elmaleh, Manuela Vasile, Yacine Khelif, Myriam Bernaudin, Philippe Chadebech, France Pirenne, Gérard Socié, Françoise Bernaudin
BACKGROUND: Children with sickle cell anemia (SCA) have an 11% risk of stroke by the age of 18. Chronic transfusion applied in patients detected to be at risk by transcranial Doppler allows a significant reduction of stroke risk. However, chronic transfusion exposes to several adverse events, including alloimmunization and iron overload, and is not curative. Hematopoietic stem cell transplantation allows termination of the transfusion program, but its benefit has not been demonstrated...
August 15, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/28820738/the-effects-of-transcranial-direct-current-stimulation-on-short-interval-intracortical-inhibition-and-intracortical-facilitation-a-systematic-review-and-meta-analysis
#7
Mana Biabani, Maryam Aminitehrani, Maryam Zoghi, Michael Farrell, Gary Egan, Shapour Jaberzadeh
Transcranial direct current stimulation (tDCS) is increasingly being used to affect the neurological conditions with deficient intracortical synaptic activities (i.e. Parkinson's disease and epilepsy). In addition, it is suggested that the lasting effects of tDCS on corticospinal excitability (CSE) have intracortical origin. This systematic review and meta-analysis aimed to examine whether tDCS has any effect on intracortical circuits. Eleven electronic databases were searched for the studies investigating intracortical changes induced by anodal (a) and cathodal (c) tDCS, in healthy individuals, using two paired-pulse transcranial magnetic stimulation (TMS) paradigms: short-interval intracortical inhibition (SICI) and intracortical facilitation (ICF)...
August 18, 2017: Reviews in the Neurosciences
https://www.readbyqxmd.com/read/28820729/head-phantoms-for-electroencephalography-and-transcranial-electric-stimulation-a-skull-material-study
#8
Alexander Hunold, Daniel Strohmeier, Patrique Fiedler, Jens Haueisen
Physical head phantoms allow the assessment of source reconstruction procedures in electroencephalography and electrical stimulation profiles during transcranial electric stimulation. Volume conduction in the head is strongly influenced by the skull, which represents the main conductivity barrier. Realistic modeling of its characteristics is thus important for phantom development. In the present study, we proposed plastic clay as a material for modeling the skull in phantoms. We analyzed five clay types varying in granularity and fractions of fire clay, each with firing temperatures from 550°C to 950°C...
August 18, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28818260/transcranial-doppler-monitoring-for-microemboli-a-marker-of-a-high-risk-carotid-plaque
#9
J David Spence
In the United States, 90% of carotid intervention is being performed for asymptomatic carotid stenosis, even though 90% of patients would be better treated with intensive medical therapy. This is being justified by comparing risks of stroke or death with medical therapy during clinical trials completed decades ago (approximately 2% per year) with risks of intervention with carotid artery stenting (CAS) versus carotid endarterectomy in recent trials that did not have a medical arm. Such extrapolations are, simply put, invalid...
March 2017: Seminars in Vascular Surgery
https://www.readbyqxmd.com/read/28817495/nursing-management-of-the-patient-undergoing-focused-ultrasound-a-new-treatment-option-for-essential-tremor
#10
Katherine Dale Shaw, Amy Sue Johnston, Shelly Rush-Evans, Susan Prather, Kathy Maynard
Essential tremor (ET) is among the most common neurological movement disorders that causes postural or action tremors, with an estimated prevalence nationwide of less than 3% of the population. The incidence of ET increases with age but often affects younger adults and has a familial trait association. Depending on disease progression, ET can cause significant limitations for individuals, in many cases, significantly limiting their ability to perform activities of daily living and occupational responsibilities...
August 16, 2017: Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses
https://www.readbyqxmd.com/read/28816916/developmental-screening-in-pediatric-sickle-cell-disease-disease-related-risk-and-screening-outcomes-in-4-year-olds
#11
Jeffrey Schatz, Alyssa Schlenz, Laura Reinman, Kelsey Smith, Carla W Roberts
OBJECTIVE: Studies of early child development in sickle cell disease (SCD) have found modest associations between disease-related risks and developmental status in infants and toddlers, but such associations are evident by early elementary school. We screened 4-year-old children with SCD using 2 screening strategies to assess if biomedical risk factors for neurologic disease are related to developmental screening outcomes at this intermediate age. METHODS: Seventy-seven 4-year-old children with SCD (M = 4...
August 4, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28816660/erratum-a-200-1380-khz-quadrifrequency-focused-ultrasound-transducer-for-neurostimulation-in-rodents-and-primates-transcranial-in-vitro-calibration-and-numerical-study-of-the-influence-of-skull-cavity
#12
Charlotte Constans, Thomas Deffieux, Pierre Pouget, Mickael Tanter, Jean-Francois Aubry
Presents correction in the paper "A 200 - 1380 kHz Quadrifrequency Focused Ultrasound Transducer For Neurostimulation In Rodents And Primates: Transcranial In Vitro Calibration And Numerical Study Of The Influence Of Skull Cavity", IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 2017, vol. 64, no 4, p. 717-724.
August 14, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28815666/dorsomedial-prefrontal-cortex-repetitive-transcranial-magnetic-stimulation-treatment-of-posttraumatic-stress-disorder-in-eating-disorders-an-open-label-case-series
#13
D Blake Woodside, Patricia Colton, Eileen Lam, Katharine Dunlop, Julia Rzeszutek, Jonathan Downar
Posttraumatic stress disorder (PTSD) is a common comorbid condition in anorexia nervosa (AN) and bulimia nervosa (BN), and may be associated with reduced response to treatment. We report on a case series employing repetitive transcranial magnetic stimulation (rTMS) with a novel target, the dorsomedial prefrontal cortex (DMPFC). Fourteen subjects with eating disorders and comorbid PTSD received 20-30 neuronavigated DMPFC-rTMS treatments on an open-label basis. PTSD symptoms were assessed pretreatment and posttreatment with the PTSD checklist-Civilian (PCL-C) and the Difficulties in Emotional Regulation Scale (DERS)...
August 16, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28814456/downregulation-of-early-visual-cortex-excitability-mediates-oscillopsia-suppression
#14
Hena Ahmad, R Edward Roberts, Mitesh Patel, Rhannon Lobo, Barry Seemungal, Qadeer Arshad, Adolfo Bronstein
OBJECTIVE: To identify in an observational study the neurophysiologic mechanisms that mediate adaptation to oscillopsia in patients with bilateral vestibular failure (BVF). METHODS: We directly probe the hypothesis that adaptive changes that mediate oscillopsia suppression implicate the early visual-cortex (V1/V2). Accordingly, we investigated V1/V2 excitability using transcranial magnetic stimulation (TMS) in 12 avestibular patients and 12 healthy controls. Specifically, we assessed TMS-induced phosphene thresholds at baseline and cortical excitability changes while performing a visual motion adaptation paradigm during the following conditions: baseline measures (i...
August 16, 2017: Neurology
https://www.readbyqxmd.com/read/28813921/effect-on-the-classification-of-motor-imagery-in-eeg-after-applying-anodal-tdcs-with-a-4%C3%A3-1-ring-montage-over-the-motor-cortex
#15
I N Angulo-Sherman, M Rodriguez-Ugarte, E Ianez, M Ortiz, J M Azorin
Transcranial direct stimulation (tDCS) is a technique for modulating brain excitability that has potential to be used in motor neurorehabilitation by enhancing motor activity, such as motor imagery (MI). tDCS effects depend on different factors, like current density and the position of the stimulating electrodes. This study presents preliminary results of the evaluation of the effect of current density on MI performance by measuring right-hand/feet MI accuracy of classification from electroencephalographic (EEG) measurements after anodal tDCS is applied with a 4×1 ring montage over the right-hand or feet motor cortex...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813878/randomized-sham-controlled-trial-based-on-transcranial-direct-current-stimulation-and-wrist-robot-assisted-integrated-treatment-on-subacute-stroke-patients-intermediate-results
#16
Stefano Mazzoleni, Vi Do Tran, Laura Iardella, Paolo Dario, Federico Posteraro
The main goal of this study is to analyse the effects of combined transcranial direct current stimulation (tDCS) and wrist robot-assisted therapy in subacute stroke patients. Twenty-four patients were included in this study and randomly assigned to the experimental (EG) or control group (CG). All participants performed wrist robot-assisted training a) in conjunction with tDCS (real stimulation for patients in EG) or b) without tDCS (sham stimulation for patients in CG). Clinical scales and kinematic parameters recorded by the robot were used for the assessment...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813867/therapeutic-effects-of-anti-gravity-treadmill-alterg-training-on-reflex-hyper-excitability-corticospinal-tract-activities-and-muscle-stiffness-in-children-with-cerebral-palsy
#17
Sh Parvin, A Taghiloo, A Irani, M Mehdi Mirbagheri
We aimed to study therapeutic effects of antigravity treadmill (AlterG) training on reflex hyper-excitability, muscle stiffness, and corticospinal tract (CST) function in children with spastic hemiplegic cerebral palsy (CP). Three children received AlterG training 3 days per week for 8 weeks as experimental group. Each session lasted 45 minutes. One child as control group received typical occupational therapy for the same amount of time. We evaluated hyper-excitability of lower limb muscles by H-reflex response...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813353/motor-cognition-and-neuroscience-in-sport-psychology
#18
REVIEW
Paul S Holmes, David J Wright
Advances in technology have allowed research in cognitive neuroscience to contribute significantly to the discipline of sport psychology. In most cases, the research has become more rigorous and has directed current thinking on the mechanisms subserving a number of psychological theories and models of practice. Currently, the three most common neuroscience techniques informing sport and exercise research are electroencephalography, transcranial magnetic stimulation and functional magnetic resonance imaging...
August 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/28808649/the-effect-of-a-single-dose-dantrolene-in-patients-with-vasospasm-following-aneurysmal-subarachnoid-hemorrhage
#19
Masih Sabouri, Mahmood Momeni, Fariborz Khorvash, Majid Rezvani, Homayon Tabesh
BACKGROUND: Cerebral vasospasm is a prolonged, occasionally severe, but reversible narrowing of the cerebral arteries that begins 3 to 5 days after the hemorrhage becomes maximal at 14 days. This study is designed to evaluate the effect of dantrolene on the reduction of vasospasm following aneurysmal subarachnoid hemorrhage (SAH). MATERIALS AND METHODS: This randomized controlled clinical trial was conducted on 32 patients with proven aneurysms in AL-Zahra hospital during 2011-2013...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28807846/the-reliability-of-commonly-used-electrophysiology-measures
#20
K E Brown, K R Lohse, I M S Mayer, G Strigaro, M Desikan, E P Casula, S Meunier, T Popa, J-C Lamy, O Odish, B R Leavitt, A Durr, R A C Roos, S J Tabrizi, J C Rothwell, L A Boyd, M Orth
BACKGROUND: Electrophysiological measures can help understand brain function both in healthy individuals and in the context of a disease. Given the amount of information that can be extracted from these measures and their frequent use, it is essential to know more about their inherent reliability. OBJECTIVE/HYPOTHESIS: To understand the reliability of electrophysiology measures in healthy individuals. We hypothesized that measures of threshold and latency would be the most reliable and least susceptible to methodological differences between study sites...
July 31, 2017: Brain Stimulation
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