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https://www.readbyqxmd.com/read/29907388/assessment-of-the-corticospinal-fiber-integrity-in-mirror-movement-disorder
#1
Bilgehan Solmaz, Mustafa Görkem Özyurt, Demir Berk Ata, Fulya Akçimen, Mohammed Shabsog, Kemal Sıtkı Türker, Hakkı Dalçik, Oktay Algin, Ayşe Nazlı Başak, Merve Özgür, Safiye Çavdar
Mirror movements are unintended movements occurring on one side of the body that mirror the contralateral voluntary ones. It has been proposed that mirror movements occur due to abnormal decussation of the corticospinal pathways. Using detailed multidisciplinary approach, we aimed to enlighten the detailed mechanism underlying the mirror movements in a case subject who is diagnosed with mirror movements of the hands and we compared the findings with the unaffected control subjects. To evaluate the characteristics of mirror movements, we used several techniques including whole exome sequencing, computed tomography, diffusion tensor imaging and transcranial magnetic stimulation...
June 12, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29905844/robotic-assisted-mri-guided-interventional-interstitial-mr-guided-focused-ultrasound-ablation-in-a-swine-model
#2
Jacquelyn MacDonell, Niravkumar Patel, Gregory Fischer, E Clif Burdette, Jiang Qian, Vaibhav Chumbalkar, Goutam Ghoshal, Tamas Heffter, Emery Williams, Matthew Gounis, Robert King, Juliette Thibodeau, Gene Bogdanov, Olivia W Brooks, Erin Langan, Roy Hwang, Julie G Pilitsis
BACKGROUND: Ablative lesions are current treatments for epilepsy and brain tumors. Interstitial magnetic resonance (MR) guided focused ultrasound (iMRgFUS) may be an alternate ablation technique which limits thermal tissue charring as compared to laser therapy (LITT) and can produce larger ablation patterns nearer the surface than transcranial MR guided focused ultrasound (tcMRgFUS). OBJECTIVE: To describe our experience with interstitial focused ultrasound (iFUS) ablations in swine, using MR-guided robotically assisted (MRgRA) delivery...
June 14, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29904802/an-update-on-repetitive-transcranial-magnetic-stimulation-for-the-treatment-of-co-morbid-pain-and-depressive-symptoms
#3
REVIEW
Jonathan H Hsu, Zafiris J Daskalakis, Daniel M Blumberger
PURPOSE: Review recent meta-analyses and clinical trials investigating the therapeutic use of repetitive transcranial magnetic stimulation (rTMS) for concurrent pain and depressive symptoms. RECENT FINDINGS: Recent meta-analyses have included both pain and depression outcomes in fibromyalgia and chronic pain. Randomized controlled trials have also been conducted in post-herpetic neuralgia, trauma-related headache, and neuropathic pain with attention to both pain and depressive symptoms...
June 14, 2018: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/29903443/nuclear-medicine-of-the-cerebellum
#4
Alessandra Vella, Mario Mascalchi
Single-photon emission computed tomography (SPECT) and positron emission tomography (PET) with different radiotracers enable regional evaluation of blood flow and glucose metabolism, of receptors and transporters of several molecules, and of abnormal deposition of peptides and proteins in the brain. The cerebellum has been used as a reference region for different radiotracers in several disease conditions. Whole-brain voxel-wise analysis is not affected by a priori knowledge bias and should be preferred. SPECT and PET have contributed to establishing the cerebellum role in motion, cognition, and emotion control in physiologic and pathophysiologic conditions...
2018: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/29902398/transcranial-magnetic-stimulation-an-item-number-is-justified
#5
Saxby Pridmore
No abstract text is available yet for this article.
June 18, 2018: Medical Journal of Australia
https://www.readbyqxmd.com/read/29901693/neurophysiological-correlates-of-bradykinesia-in-parkinson-s-disease
#6
Matteo Bologna, Andrea Guerra, Giulia Paparella, Laura Giordo, Danilo Alunni Fegatelli, Anna Rita Vestri, John C Rothwell, Alfredo Berardelli
Many neurophysiological abnormalities have been described in the primary motor cortex of patients with Parkinson's disease. However, it is unclear whether there is any relationship between them and bradykinesia, one of the cardinal motor features of the condition. In the present study we aimed to investigate whether objective measures of bradykinesia in Parkinson's disease have any relationship with neurophysiological measures in primary motor cortex as assessed by means of transcranial magnetic stimulation techniques...
June 12, 2018: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/29901637/extracranial-intracranial-bypass-in-medial-sphenoid-ridge-meningioma-associated-with-severe-stenosis-of-the-intracranial-segments-of-the-internal-carotid-artery-a-case-report
#7
Yabo Huang, Zhong Wang, Qingdong Han
RATIONALE: Tumor resection and extracranial-intracranial bypass concerning medial sphenoid ridge meningioma associated with severe stenosis of the internal carotid artery (ICA) of intracranial segments has been rarely presented. Effective treatment as to the complex lesions may be complicated. Tumor resection and cerebrovascular protection should be both taken into consideration. PATIENT CONCERNS: We presented one case of medial sphenoid ridge meningioma associated with severe stenosis of the internal carotid artery of intracranial segments...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29901497/transcranial-direct-current-stimulation-in-the-acute-depressive-episode-a-systematic-review-of-current-knowledge
#8
Lucas Borrione, Adriano H Moffa, Donel Martin, Colleen K Loo, Andre R Brunoni
Major depressive disorder is a severe, refractory mental disorder. Only one third of patients treated with antidepressants achieve remission after 3 trials, while subject to adverse effects. Therefore, the investigation of alternative treatments is paramount. The aim of this systematic review was to summarize the most recent evidence of transcranial direct current stimulation (tDCS) intervention for the acute phase of major depressive disorder. A PubMed search was performed including the terms "transcranial direct current stimulation" OR "transcranial direct stimulation" OR "tDCS" AND "major depressive disorder" OR "major depression" OR "depression" AND "trial...
June 12, 2018: Journal of ECT
https://www.readbyqxmd.com/read/29901496/augmentation-effect-of-low-frequency-repetitive-transcranial-magnetic-stimulation-over-presupplementary-motor-area-in-obsessive-compulsive-disorder-a-randomized-controlled-trial
#9
Shyam Sundar Arumugham, Subhasini Vs, Madhuri Hn, Vinay B, Malvika Ravi, Eesha Sharma, Jagadisha Thirthalli, Y C Janardhan Reddy
OBJECTIVE: The current study investigated the efficacy of low-frequency repetitive transcranial magnetic stimulation (rTMS) over bilateral presupplementary motor area (pre-SMA) in patients suffering from obsessive-compulsive disorder (OCD) with partial/poor response to pharmacotherapy, in a double-blinded randomized sham controlled trial. METHOD: Forty subjects with OCD, who were on stable medications with partial/poor response to pharmacotherapy were randomly divided into 2 groups (n = 20 in each group), to receive either active or sham low-frequency rTMS over bilateral pre-SMA...
June 12, 2018: Journal of ECT
https://www.readbyqxmd.com/read/29900591/patterns-of-solid-particle-embolization-during-transcatheter-aortic-valve-implantation-and-correlation-with-aortic-valve-calcification
#10
Suneil K Aggarwal, Nicola Delahunty Rn, Leon J Menezes, Richard Perry, Bethany Wong, Markus Reinthaler, Muhiddin Ozkor, Michael J Mullen
OBJECTIVES: To evaluate solid embolization during transcatheter aortic valve implantation (TAVI) and correlate this with aortic valve calcification. BACKGROUND: There is a known stroke risk with TAVI, thought partly to be due to dislodgement of native aortic valve particles during implantation. However, to date there is little evidence that aortic valve calcification actually impacts embolic risk. METHODS: Transcranial Doppler (TCD) was performed on consecutive suitable patients undergoing TAVI, using hardware and software enabling differentiation between solid and gaseous emboli...
June 13, 2018: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29899693/mechanisms-of-transcranial-magnetic-stimulation-treating-on-post-stroke-depression
#11
REVIEW
Xiaoqin Duan, Gang Yao, Zhongliang Liu, Ranji Cui, Wei Yang
Post-stroke depression (PSD) is a neuropsychiatric affective disorder that can develop after stroke. Patients with PSD show poorer functional and recovery outcomes than patients with stroke who do not suffer from depression. The risk of suicide is also higher in patients with PSD. PSD appears to be associated with complex pathophysiological mechanisms involving both psychological and psychiatric problems that are associated with functional deficits and neurochemical changes secondary to brain damage. Transcranial magnetic stimulation (TMS) is a non-invasive way to investigate cortical excitability via magnetic stimulation of the brain...
2018: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29899691/brain-functional-connectivity-changes-after-transcranial-direct-current-stimulation-in-epileptic-patients
#12
Franca Tecchio, Carlo Cottone, Camillo Porcaro, Andrea Cancelli, Vincenzo Di Lazzaro, Giovanni Assenza
Focal epilepsy is a network pathology, where the brain connectivity of the epileptic focus (EF) influences seizure frequency and cortical dysfunction. Growing evidence supports a clinical efficacy of cathodal transcranial direct current stimulation (ctDCS) in drug-resistant epilepsy (DRE). ctDCS effects can be merely attributed to the inhibition of cortical excitability, which is abnormally increased in epilepsy, but its effect on brain network of DRE patients has never been reported. We aimed at exploring the hypothesis that functional connectivity (FC) changes may explain part of ctDCS clinical effects in DRE patients...
2018: Frontiers in Neural Circuits
https://www.readbyqxmd.com/read/29899686/cortical-statistical-correlation-tomography-of-eeg-resting-state-networks
#13
Chuang Li, Han Yuan, Guofa Shou, Yoon-Hee Cha, Sridhar Sunderam, Walter Besio, Lei Ding
Resting state networks (RSNs) have been found in human brains during awake resting states. RSNs are composed of spatially distributed regions in which spontaneous activity fluctuations are temporally and dynamically correlated. A new computational framework for reconstructing RSNs with human EEG data has been developed in the present study. The proposed framework utilizes independent component analysis (ICA) on short-time Fourier transformed inverse source maps imaged from EEG data and statistical correlation analysis to generate cortical tomography of electrophysiological RSNs...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29898858/current-evidence-on-the-potential-therapeutic-applications-of-transcranial-magnetic-stimulation-in-multiple-sclerosis-a-systematic-review-of-the-literature
#14
M León Ruiz, M Sospedra, S Arce Arce, J Tejeiro-Martínez, J Benito-León
INTRODUCTION: A growing number of studies have evaluated the effects of transcranial magnetic stimulation (TMS) for the symptomatic treatment of multiple sclerosis (MS). METHODS: We performed a PubMed search for articles, recent books, and recommendations from the most relevant clinical practice guidelines and scientific societies regarding the use of TMS as symptomatic treatment in MS. CONCLUSIONS: Excitatory electromagnetic pulses applied to the affected cerebral hemisphere allow us to optimise functional brain activity, including the transmission of nerve impulses through the demyelinated corticospinal pathway...
June 10, 2018: Neurología: Publicación Oficial de la Sociedad Española de Neurología
https://www.readbyqxmd.com/read/29898628/confident-false-memories-for-spatial-location-are-mediated-by-v1
#15
Jessica M Karanian, Scott D Slotnick
Prior functional magnetic resonance imaging (fMRI) results suggest that true memories, but not false memories, activate early sensory cortex. It is thought that false memories, which reflect conscious processing, do not activate early sensory cortex because these regions are associated with nonconscious processing. We posited that false memories may activate the earliest visual cortical processing region (i.e., V1) when task conditions are manipulated to evoke conscious processing in this region. In an fMRI experiment, abstract shapes were presented to the left or right of fixation during encoding...
June 13, 2018: Cognitive Neuroscience
https://www.readbyqxmd.com/read/29898612/altered-cortical-excitability-in-persistent-idiopathic-facial-pain
#16
Ricardo Galhardoni, Daniel Ciampi de Andrade, Mariana Yt Puerta, Andre R Brunoni, Bruna Lr Varotto, José Tt de Siqueira, Manoel J Teixeira, Silvia Rdt Siqueira
Introduction Persistent idiopathic facial pain is a refractory and disabling condition of unknown mechanism and etiology. It has been suggested that persistent idiopathic facial pain patients have not only peripheral generators of pain, but also central nervous system changes that would contribute to the persistence of symptoms. We hypothesized that persistent idiopathic facial pain would have changes in brain cortical excitability as measured by transcranial magnetic stimulation compared to healthy controls...
January 1, 2018: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/29897597/high-frequency-neuronavigated-rtms-in-auditory-verbal-hallucinations-a-pilot-double-blind-controlled-study-in-patients-with-schizophrenia
#17
Sonia Dollfus, Nemat Jaafari, Olivier Guillin, Benoit Trojak, Marion Plaze, Ghassen Saba, Cécilia Nauczyciel, Aurélie Montagne Larmurier, Nathalie Chastan, Vincent Meille, Marie-Odile Krebs, Samar S Ayache, Jean Pascal Lefaucheur, Annick Razafimandimby, Elise Leroux, Rémy Morello, Jean Marie Batail, Perrine Brazo, Nicolas Lafay, Issa Wassouf, Ghina Harika-Germaneau, Remy Guillevin, Carole Guillevin, Emmanuel Gerardin, Maud Rotharmel, Benoit Crépon, Raphael Gaillard, Christophe Delmas, Gael Fouldrin, Guillaume Laurent, Clément Nathou, Olivier Etard
INTRODUCTION: Despite extensive testing, the efficacy of low-frequency (1 Hz) repetitive transcranial magnetic stimulation (rTMS) of temporo-parietal targets for the treatment of auditory verbal hallucinations (AVH) in patients with schizophrenia is still controversial, but promising results have been reported with both high-frequency and neuronavigated rTMS. Here, we report a double-blind sham-controlled study to assess the efficacy of high-frequency (20 Hz) rTMS applied over a precise anatomical site in the left temporal region using neuronavigation...
April 6, 2018: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29897047/the-effects-of-image-homogenisation-on-simulated-transcranial-ultrasound-propagation
#18
James L B Robertson, Jillian Urban, Joel Stitzel, Bradley E Treeby
Transcranial transmission of ultrasound is increasingly used in a variety of clinical and research applications, including high intensity ablation, opening the blood brain barrier, and neural stimulation. Numerical simulations of ultrasound propagation in the head are used to enable effective transcranial focusing and predict intracranial fields. Such simulations require maps of the acoustic properties of the head, which can be derived from clinical CT images. However, the spatial resolution of these images is typically coarser than the scale of heterogeneities within the skull bone, which are known to exert a major influence on ultrasound propagation...
June 13, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29896293/three-dimensional-transcranial-microbubble-imaging-for-guiding-volumetric-ultrasound-mediated-blood-brain-barrier-opening
#19
Ryan M Jones, Lulu Deng, Kogee Leung, Dallan McMahon, Meaghan A O'Reilly, Kullervo Hynynen
Focused ultrasound (FUS)-mediated blood-brain barrier (BBB) opening recently entered clinical testing for targeted drug delivery to the brain. Sources of variability exist in the current procedures, motivating the development of real-time monitoring and control techniques to improve treatment safety and efficacy. Here we used three-dimensional (3D) transcranial microbubble imaging to calibrate FUS exposure levels for volumetric BBB opening. Methods: Using a sparse hemispherical transmit/receive ultrasound phased array, pulsed ultrasound was focused transcranially into the thalamus of rabbits during microbubble infusion and multi-channel 3D beamforming was performed online with receiver signals captured at the subharmonic frequency...
2018: Theranostics
https://www.readbyqxmd.com/read/29896093/unilateral-application-of-cathodal-tdcs-reduces-transcallosal-inhibition-and-improves-visual-acuity-in-amblyopic-patients
#20
Tommaso Bocci, Francesco Nasini, Matteo Caleo, Laura Restani, Davide Barloscio, Gianluca Ardolino, Alberto Priori, Lamberto Maffei, Marco Nardi, Ferdinando Sartucci
Objective: Amblyopia is a neurodevelopmental disorder characterized by visual acuity and contrast sensitivity loss, refractory to pharmacological and optical treatments in adulthood. In animals, the corpus callosum (CC) contributes to suppression of visual responses of the amblyopic eye. To investigate the role of interhemispheric pathways in amblyopic patients, we studied the response of the visual cortex to transcranial Direct Current Stimulation (tDCS) applied over the primary visual area (V1) contralateral to the "lazy eye...
2018: Frontiers in Behavioral Neuroscience
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