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https://www.readbyqxmd.com/read/28979733/key-success-factors-of-health-research-centers-a-mixed-method-study
#1
Shahram Tofighi, Ehsan Teymourzadeh, Majid Heydari
BACKGROUND: In order to achieve success in future goals and activities, health research centers are required to identify their key success factors. OBJECTIVE: This study aimed to extract and rank the factors affecting the success of research centers at one of the medical universities in Iran. METHODS: This study is a mixed method (qualitative-quantitative) study, which was conducted between May to October in 2016. The study setting was 22 health research centers...
August 2017: Electronic Physician
https://www.readbyqxmd.com/read/28963916/case-based-simulation-in-mri-for-suspected-appendicitis-in-children
#2
Hansel J Otero, Anilawan Smitthimedhin, Crystal C Wang, Mark D Heitzmann
PURPOSE: To establish the effect on diagnostic confidence of a simulation setting, in which radiologists re-interpret anonymized pediatric MRI cases. MATERIALS: In this IRB-approved study, participants completed surveys rating confidence before and after interpreting 10 MRI cases for suspected appendicitis in children. RESULTS: 18 radiologists (4 faculty, 5 fellows, and 9 residents) correctly identified an average of 7.44 cases (range 5-9)...
September 22, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/28961038/focused-ultrasound-for-immuno-adjuvant-treatment-of-pancreatic-cancer-an-emerging-clinical-paradigm-in-the-era-of-personalized-oncotherapy
#3
Ezekiel Maloney, Tanya Khokhlova, Venu G Pillarisetty, George R Schade, Elizabeth A Repasky, Yak-Nam Wang, Lorenzo Giuliani, Matteo Spring, Joo Ha Hwang
Current clinical treatment regimens, including many emergent immune strategies (e.g., checkpoint inhibitors) have done little to affect the devastating course of pancreatic ductal adenocarcinoma (PDA). Clinical trials for PDA often employ multi-modal treatment, and have started to incorporate stromal-targeted therapies, which have shown promising results in early reports. Focused ultrasound (FUS) is one such therapy that is uniquely equipped to address local and systemic limitations of conventional cancer therapies as well as emergent immune therapies for PDA...
September 29, 2017: International Reviews of Immunology
https://www.readbyqxmd.com/read/28768730/detection-of-plasmodium-infection-by-the-illumigene-malaria-assay-compared-to-reference-microscopy-and-real-time-pcr
#4
Candace Rypien, Barbara Chow, Wilson W Chan, Deirdre L Church, Dylan R Pillai
Malaria is one of the leading causes of infectious disease in travelers returning from the tropics. The diagnosis of malaria is typically performed by examining Giemsa-stained thick and thin peripheral blood smears, which is time consuming, labor intensive, and requires high levels of proficiency. Alternatively, loop-mediated isothermal amplification (LAMP) is a new molecular method, which is rapid, sensitive, and requires less capital equipment and technological training. We conducted a retrospective study comparing two formats of a commercial LAMP assay (Meridian illumigene malaria [M] and malaria Plus [MP]) versus reference microscopy on archived blood specimens (n = 140) obtained from unique returning travelers suspected of having malaria...
October 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28700972/evaluating-the-use-of-in-situ-turbidity-measurements-to-quantify-fluvial-sediment-and-phosphorus-concentrations-and-fluxes-in-agricultural-streams
#5
Marc Stutter, Julian J C Dawson, Miriam Glendell, Fiona Napier, Jacqueline M Potts, James Sample, Andrew Vinten, Helen Watson
Accurate quantification of suspended sediments (SS) and particulate phosphorus (PP) concentrations and loads is complex due to episodic delivery associated with storms and management activities often missed by infrequent sampling. Surrogate measurements such as turbidity can improve understanding of pollutant behaviour, providing calibrations can be made cost-effectively and with quantified uncertainties. Here, we compared fortnightly and storm intensive water quality sampling with semi-continuous turbidity monitoring calibrated against spot samples as three potential methods for determining SS and PP concentrations and loads in an agricultural catchment over two-years...
December 31, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28665903/man-versus-machine-comparing-double-data-entry-and-optical-mark-recognition-for-processing-cahps-survey-data
#6
Matthew Fifolt, Justin Blackburn, David J Rhodes, Shemeka Gillespie, Aleena Bennett, Paul Wolff, Andrew Rucks
OBJECTIVE: Historically, double data entry (DDE) has been considered the criterion standard for minimizing data entry errors. However, previous studies considered data entry alternatives through the limited lens of data accuracy. This study supplies information regarding data accuracy, operational efficiency, and cost for DDE and Optical Mark Recognition (OMR) for processing the Consumer Assessment of Healthcare Providers and Systems 5.0 survey. METHODS: To assess data accuracy, we compared error rates for DDE and OMR by dividing the number of surveys that were arbitrated by the total number of surveys processed for each method...
July 2017: Quality Management in Health Care
https://www.readbyqxmd.com/read/28664931/the-evolution-of-brachytherapy-for-prostate-cancer
#7
REVIEW
Nicholas G Zaorsky, Brian J Davis, Paul L Nguyen, Timothy N Showalter, Peter J Hoskin, Yasuo Yoshioka, Gerard C Morton, Eric M Horwitz
Brachytherapy (BT), using low-dose-rate (LDR) permanent seed implantation or high-dose-rate (HDR) temporary source implantation, is an acceptable treatment option for select patients with prostate cancer of any risk group. The benefits of HDR-BT over LDR-BT include the ability to use the same source for other cancers, lower operator dependence, and - typically - fewer acute irritative symptoms. By contrast, the benefits of LDR-BT include more favourable scheduling logistics, lower initial capital equipment costs, no need for a shielded room, completion in a single implant, and more robust data from clinical trials...
June 30, 2017: Nature Reviews. Urology
https://www.readbyqxmd.com/read/28638988/same-day-genomic-and-epigenomic-diagnosis-of-brain-tumors-using-real-time-nanopore-sequencing
#8
Philipp Euskirchen, Franck Bielle, Karim Labreche, Wigard P Kloosterman, Shai Rosenberg, Mailys Daniau, Charlotte Schmitt, Julien Masliah-Planchon, Franck Bourdeaut, Caroline Dehais, Yannick Marie, Jean-Yves Delattre, Ahmed Idbaih
Molecular classification of cancer has entered clinical routine to inform diagnosis, prognosis, and treatment decisions. At the same time, new tumor entities have been identified that cannot be defined histologically. For central nervous system tumors, the current World Health Organization classification explicitly demands molecular testing, e.g., for 1p/19q-codeletion or IDH mutations, to make an integrated histomolecular diagnosis. However, a plethora of sophisticated technologies is currently needed to assess different genomic and epigenomic alterations and turnaround times are in the range of weeks, which makes standardized and widespread implementation difficult and hinders timely decision making...
June 21, 2017: Acta Neuropathologica
https://www.readbyqxmd.com/read/28632188/smartphone-based-food-diagnostic-technologies-a-review
#9
REVIEW
Giovanni Rateni, Paolo Dario, Filippo Cavallo
A new generation of mobile sensing approaches offers significant advantages over traditional platforms in terms of test speed, control, low cost, ease-of-operation, and data management, and requires minimal equipment and user involvement. The marriage of novel sensing technologies with cellphones enables the development of powerful lab-on-smartphone platforms for many important applications including medical diagnosis, environmental monitoring, and food safety analysis. This paper reviews the recent advancements and developments in the field of smartphone-based food diagnostic technologies, with an emphasis on custom modules to enhance smartphone sensing capabilities...
June 20, 2017: Sensors
https://www.readbyqxmd.com/read/28619401/assessment-of-surgical-and-trauma-capacity-in-potos%C3%A3-bolivia
#10
Kevin J Blair, Marissa A Boeck, José Luis Gallardo Barrientos, José Luis Hidalgo López, Irene B Helenowski, Benedict C Nwomeh, Michael B Shapiro, Mamta Swaroop
BACKGROUND: Scaling up surgical and trauma care in low- and middle-income countries could prevent nearly 2 million annual deaths. Various survey instruments exist to measure surgical and trauma capacity, including Personnel, Infrastructure, Procedures, Equipment, and Supplies (PIPES) and International Assessment of Capacity for Trauma (INTACT). OBJECTIVE: We sought to evaluate surgical and trauma capacity in the Bolivian department of Potosí using a combined PIPES and INTACT tool, with additional questions to further inform intervention targets...
March 2017: Annals of Global Health
https://www.readbyqxmd.com/read/28617202/hospital-capital-investment-during-the-great-recession
#11
Sung Choi
Hospital capital investment is important for acquiring and maintaining technology and equipment needed to provide health care. Reduction in capital investment by a hospital has negative implications for patient outcomes. Most hospitals rely on debt and internal cash flow to fund capital investment. The great recession may have made it difficult for hospitals to borrow, thus reducing their capital investment. I investigated the impact of the great recession on capital investment made by California hospitals...
January 1, 2017: Inquiry: a Journal of Medical Care Organization, Provision and Financing
https://www.readbyqxmd.com/read/28607243/costing-of-immunization-service-provision-in-kalutara-district-sri-lanka-a-cross-sectional-study
#12
Hemali Jayasekara, Amala De Silva, Ananda Amarasinghe
BACKGROUND: Immunization is regarded as the single most cost-effective way to prevent vaccine-preventable diseases. With the rising cost of the National Immunization Programme (NIP) in Sri Lanka, immunization costing studies could help programme managers to ensure sustainable immunization financing in the country. METHODS: Four medical officer of health (MOH) divisions in Kalutara district were included, to estimate the cost incurred for the NIP programme. Fifteen immunization clinics from urban and rural settings were selected from the selected MOH divisions, by a simple random sampling method...
September 2016: WHO South-East Asia Journal of Public Health
https://www.readbyqxmd.com/read/28598772/implementation-of-a-novel-taxonomy-based-on-cognitive-work-analysis-in-the-assessment-of-safety-performance
#13
Toivo Niskanen
PURPOSE: The aim of this study was to examine how the developed taxonomy of cognitive work analysis (CWA) can be applied in combination with statistical analysis regarding different socio-technical categories. MATERIALS AND METHODS: This study applied a combination of quantitative and qualitative methodologies. Workers (n=120) and managers (n=85) in the chemical industry were asked in a questionnaire how different OSH measures were being implemented. The exploration of the qualitative CWA taxonomy consisted of an analysis of the following topics: (1) Work domain; (2) Control task; (3) Strategies; (4) Social organization and cooperation; and (5) Worker competencies...
June 9, 2017: International Journal of Occupational Safety and Ergonomics: JOSE
https://www.readbyqxmd.com/read/28574303/technological-solutions-for-an-effective-health-surveillance-system-for-road-traffic-crashes-in-burkina-faso
#14
Emmanuel Bonnet, Aude Nikiéma, Zoumana Traoré, Salifou Sidbega, Valéry Ridde
BACKGROUND: In the early 2000s, electronic surveillance systems began to be developed to collect and transmit data on infectious diseases in low-income countries (LICs) in real-time using mobile technologies. Such surveillance systems, however, are still very rare in Africa. Among the non-infectious epidemics to be surveilled are road traffic injuries, which constitute major health events and are the fifth leading cause of mortality in Africa. This situation also prevails in Burkina Faso, whose capital city, Ouagadougou, is much afflicted by this burden...
2017: Global Health Action
https://www.readbyqxmd.com/read/28525513/an-observational-assessment-of-anesthesia-capacity-in-madagascar-as-a-prerequisite-to-the-development-of-a-national-surgical-plan
#15
Linden S Baxter, Vaonandianina A Ravelojaona, Hasiniaina N Rakotoarison, Alison Herbert, Emily Bruno, Kristin L Close, Vanessa Andean, Hery H Andriamanjato, Mark G Shrime, Michelle C White
BACKGROUND: The global lack of anesthesia capacity is well described, but country-specific data are needed to provide country-specific solutions. We aimed to assess anesthesia capacity in Madagascar as part of the development of a Ministry of Health national surgical plan. METHODS: As part of a nationwide surgical safety quality improvement project, we surveyed 19 of 22 regional hospitals, representing surgical facilities caring for 75% of the total population. The assessment was divided into 3 areas: anesthesia workforce density, infrastructure and equipment, and medications...
June 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28493987/barriers-to-utilization-of-childbirth-services-of-a-rural-birthing-center-in-nepal-a-qualitative-study
#16
Resham Bahadur Khatri, Tara Prasad Dangi, Rupesh Gautam, Khadka Narayan Shrestha, Caroline S E Homer
BACKGROUND: Maternal mortality and morbidity are public health problems in Nepal. In rural communities, many women give birth at home without the support of a skilled birth attendant, despite the existence of rural birthing centers. The aim of this study was to explore the barriers and provide pragmatic recommendations for better service delivery and use of rural birthing centers. METHODS: We conducted 26 in-depth interviews with service users and providers, and three focus group discussions with community key informants in a rural community of Rukum district...
2017: PloS One
https://www.readbyqxmd.com/read/28479843/usp-800-adds-significant-safety-standards-facility-upgrades-needed-to-protect-employees-from-hazardous-drugs
#17
Bruce E Beans
The new USP standard for handling hazardous drugs (HDs) will require millions of dollars in capital outlays for facility and equipment upgrades and also requires in-depth assessments of each HD that facilities handle, significant workflow and work practice changes, and thorough staff training.
May 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28459563/how-much-will-it-cost-to-monitor-microbial-drinking-water-quality-in-sub-saharan-africa
#18
Caroline Delaire, Rachel Peletz, Emily Kumpel, Joyce Kisiangani, Robert Bain, Ranjiv Khush
Microbial water quality monitoring is crucial for managing water resources and protecting public health. However, institutional testing activities in sub-Saharan Africa are currently limited. Because the economics of water quality testing are poorly understood, the extent to which cost may be a barrier to monitoring in different settings is unclear. This study used cost data from 18 African monitoring institutions (piped water suppliers and health surveillance agencies in six countries) and estimates of water supply type coverage from 15 countries to assess the annual financial requirements for microbial water testing at both national and regional levels, using World Health Organization recommendations for sampling frequency...
June 6, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28399707/fine-tuning-of-process-parameters-for-improving-briquette-production-from-palm-kernel-shell-gasification-waste
#19
Alireza Bazargan, Sarah L Rough, Gordon McKay
Palm kernel shell biochars (PKSB) ejected as residues from a gasifier have been used for solid fuel briquette production. With this approach, palm kernel shells can be used for energy production twice: first, by producing rich syngas during gasification; second, by compacting the leftover residues from gasification into high calorific value briquettes. Herein, the process parameters for the manufacture of PKSB biomass briquettes via compaction are optimized. Two possible optimum process scenarios are considered...
May 5, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28380265/how-do-i-participate-in-t-cell-immunotherapy
#20
REVIEW
Megan M Suhoski Davis, David H McKenna, Philip J Norris
T cells play a key role in the adaptive immune response, and the ability to manipulate T cells for therapeutic uses has advanced in the past decade. Infusion of expanded or engineered T cells can potentially be used to treat cancer, viral infections, graft-versus-host disease, and organ transplant rejection. The role that blood banks play in the manufacture and distribution of T-cell therapeutics is still being defined. Given the regulatory framework of blood banks, they are well positioned to collect raw material for manufacture of T-cell therapies and to distribute finished product to hospitals in support of clinical trials or eventually for licensed products...
May 2017: Transfusion
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