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https://www.readbyqxmd.com/read/28220717/merger-acquisition-and-capital-expenditure-in-health-care
#1
Wenjing Ouyang, Peter E Hilsenrath
Investment, especially through merger and acquisition (M&A), is a leading topic of concern among health care managers. In addition, the implications of this activity for organization and market concentration are of great interest to policy makers. Using a sample of 2256 firm-year observations in the health care industry during the period from 1985 to 2011, this article provides novel evidence that managers learn from financial markets in making capital expenditure (CAPEX) and M&A investment decisions. Within the industry, managers in the Drugs subsector are most likely to do so, whereas managers in the Medical Equipment and Supplies are least likely to do so...
January 2017: Inquiry: a Journal of Medical Care Organization, Provision and Financing
https://www.readbyqxmd.com/read/28152680/recommendations-for-the-delivery-of-focal-tumor-ablation-services
#2
Cassandra McKay, Jonathan Wang, Fulvia Baldassarre, Amanda Wong, Deanna Langer, John Kachura, Julian Dobranowski
: 106 Background: The objective of this work was to develop recommendations for the organization and delivery of focal tumor ablation services. New, minimally-invasive ablation technologies such as radiofrequency ablation (RFA), microwave ablation (MWA), and transcatheter arterial chemoembolization (TACE) offer treatment options for patients with a variety of cancers. These emerging therapies can improve patient care (minimize side-effects, offer more rapid recovery with comparable or enhanced outcomes) compared to traditional approaches...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28145566/optimization-of-a-biotechnological-multiproduct-batch-plant-design-for-the-manufacture-of-four-different-products-a-real-case-scenario
#3
G Sandoval, D Espinoza, N Figueroa, J A Asenjo
In this work a biotechnological multiproduct batch plant that manufactures four different recombinant proteins for human application is described in some detail. This batch plant design is then optimized with regards to the size of equipment using a mixed-integer linear programming (MILP) formulation recently developed by us in order to find a hypothetical new biotechnological batch plant based on the information of real known processes for the production of the four recombinant protein products. The real plant was divided for practical purposes into 2 sub-processes or facilities: a fermentation facility and a purification facility...
February 1, 2017: Biotechnology and Bioengineering
https://www.readbyqxmd.com/read/28129716/potential-and-clinical-translation-of-oncolytic-measles-viruses
#4
Steven Robinson, Evanthia Galanis
Oncolytic viruses represent a novel treatment modality that is unencumbered by the standard resistance mechanisms limiting the therapeutic efficacy of conventional antineoplastic agents. Attenuated engineered measles virus strains derived from the Edmonston vaccine lineage have undergone extensive preclinical evaluation and have demonstrated an ability to infect, resulting in antitumor effect with a broad variety of malignancies. They have laid the foundation for multiple future clinical trials in both solid and hematologic malignancies, which have demonstrated safety, biologic activity and the ability to elicit antitumor immune responses...
January 27, 2017: Expert Opinion on Biological Therapy
https://www.readbyqxmd.com/read/28117890/costs-of-food-safety-investments-in-the-meat-and-poultry-slaughter-industries
#5
REVIEW
Catherine L Viator, Mary K Muth, Jenna E Brophy, Gary Noyes
To develop regulations efficiently, federal agencies need to know the costs of implementing various regulatory alternatives. As the regulatory agency responsible for the safety of meat and poultry products, the U.S. Dept. of Agriculture's Food Safety and Inspection Service is interested in the costs borne by meat and poultry establishments. This study estimated the costs of developing, validating, and reassessing hazard analysis and critical control points (HACCP), sanitary standard operating procedures (SSOP), and sampling plans; food safety training for new employees; antimicrobial equipment and solutions; sanitizing equipment; third-party audits; and microbial tests...
January 24, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28116057/contrasting-behavior-between-two-populations-of-an-ice-obligate-predator-in-east-antarctica
#6
Karine Heerah, Mark Hindell, Virginia Andrew-Goff, Iain Field, Clive R McMahon, Jean-Benoît Charrassin
The Austral autumn-winter is a critical period for capital breeders such as Weddell seals that must optimize resource acquisition and storage to provision breeding in the subsequent spring. However, how Weddell seals find food in the winter months remains poorly documented. We equipped adult Weddell seals after their annual molt with satellite-relayed data loggers at two sites in East Antarctica: Dumont D'Urville (n = 12, DDU) and Davis (n = 20). We used binomial generalized mixed-effect models to investigate Weddell seals' behavioral response (i...
January 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28027164/meeting-the-needs-for-radiation-protection-diagnostic-imaging
#7
Donald P Frush
Radiation and potential risk during medical imaging is one of the foremost issues for the imaging community. Because of this, there are growing demands for accountability, including appropriate use of ionizing radiation in diagnostic and image-guided procedures. Factors contributing to this include increasing use of medical imaging; increased scrutiny (from awareness to alarm) by patients/caregivers and the public over radiation risk; and mounting calls for accountability from regulatory, accrediting, healthcare coverage (e...
February 2017: Health Physics
https://www.readbyqxmd.com/read/28024969/ultrasound-guidance-reduces-percutaneous-nephrolithotomy-cost-compared-to-fluoroscopy
#8
Matthew Hudnall, Manint Usawachintachit, Ian Metzler, David T Tzou, Brittany Harrison, Errol Lobo, Thomas Chi
OBJECTIVE: To examine the cost factors associated with ultrasound and fluoroscopic guidance for percutaneous nephrolithotomy (PCNL) and to determine which method can be performed at a lower cost per case. METHODS: A cost comparison study was performed utilizing clinical data from a prospectively maintained research database. We included the most recent 33 consecutive ultrasound-guided PCNL cases in 2016 and the most recent 40 consecutive fluoroscopy-guided PCNL cases before the operative surgeon transitioned to ultrasound guidance in May 2014...
December 23, 2016: Urology
https://www.readbyqxmd.com/read/27990540/plasma-free-reversible-and-irreversible-microfluidic-bonding
#9
M Chu, T T Nguyen, E K Lee, J L Morival, M Khine
We demonstrate a facile, plasma free process to fabricate both reversibly and irreversibly sealed microfluidic chips using a PDMS-based adhesive polymer mixture. This is a versatile method that is compatible with current PDMS microfluidics processes. It allows for easier fabrication of multilayer microfluidic devices and is compatible with micropatterning of proteins for cell culturing. When combined with our Shrinky-Dink microfluidic prototyping, complete microfluidic device fabrication can be performed without the need for any capital equipment, making microfluidics accessible to the classroom...
December 19, 2016: Lab on a Chip
https://www.readbyqxmd.com/read/27987615/practice-patterns-of-endovenous-ablation-therapy-for-the-treatment-of-venous-reflux-disease
#10
Faisal Aziz, Jose Diaz, John Blebea, Fedor Lurie
OBJECTIVE: The purpose of this study was to assess practice patterns of endovenous ablation therapy for the treatment of venous reflux disease among the vein specialist members of the American Venous Forum (AVF). METHODS: An online survey was conducted of AVF members designed to identify demographics, treatment practices, and clinical variables in the selection of vein ablation devices. RESULTS: The survey was distributed to 798 practicing physicians, of whom 129 (16%) responded...
January 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/27958195/assessment-of-radiological-protection-systems-among-diagnostic-radiology-facilities-in-north-east-india
#11
Thokchom Dewan Singh, T Jayaraman, B Arunkumar Sharma
This study aims to assess the adequacy level of radiological protection systems available in the diagnostic radiology facilities located in three capital cities of North East (NE) India. It further attempts to understand, using a multi-disciplinary approach, how the safety codes/standards in diagnostic radiology framed by the Atomic Energy Regulatory Board (AERB) and the International Atomic Energy Agency (IAEA) to achieve adequate radiological protection in facilities, have been perceived, conceptualized, and applied accordingly in these facilities...
December 13, 2016: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/27904258/cost-analysis-of-a-disaster-facility-at-an-apex-tertiary-care-trauma-center-of-india
#12
Sheetal Singh, Shakti Gupta, Anoop Daga, Vijaydeep Siddharth, LaxmiTej Wundavalli
INTRODUCTION: For the Commonwealth Games 2010, Jai Prakash Narayan Apex Trauma Centre (JPNATC) of India had been directed by the Director General Health Services and Ministry of Health and Family Welfare, Government of India, to set up a specialized unit for the definitive management of the injured/unwell athletes, officials, and related personnel coming for the Commonwealth Games in October 2010. The facility included a 20-bedded fully equipped ward, six ICU beds with ventilator capacity, one very very important person observation area, one perioperative management cubicle, and one fully modular and integrated operating room...
October 2016: Journal of Emergencies, Trauma, and Shock
https://www.readbyqxmd.com/read/27853031/the-post-ebola-virus-disease-scourge-in-nigeria-individual-levels-of-preparedness-among-physicians-in-the-federal-capital-territory-abuja
#13
Adewale L Alli, Maxwell M Nwegbu, Perpetua U Ibekwe, Titus S Ibekwe
BACKGROUND: Ebola virus disease (EVD) is a viral hemorrhagic illness with great propensity for spread across international borders. The latest outbreak in the West African region, which involved Nigeria, was the worst among previously documented 25 outbreaks since discovery in 1976. The Nigerian response toward attaining Ebola free status was phenomenal and a case study for most nations. However, the persistence of EVD in West Africa is still a risk to recurrence, hence, the need to assess the level of consciousness of Nigerian physicians towards this...
October 2016: Annals of African Medicine
https://www.readbyqxmd.com/read/27803594/a-time-and-motion-approach-to-micro-costing-of-high-throughput-genomic-assays
#14
S Costa, D A Regier, B Meissner, I Cromwell, S Ben-Neriah, E Chavez, S Hung, C Steidl, D W Scott, M A Marra, S J Peacock, J M Connors
BACKGROUND: Genomic technologies are increasingly used to guide clinical decision-making in cancer control. Economic evidence about the cost-effectiveness of genomic technologies is limited, in part because of a lack of published comprehensive cost estimates. In the present micro-costing study, we used a time-and-motion approach to derive cost estimates for 3 genomic assays and processes-digital gene expression profiling (gep), fluorescence in situ hybridization (fish), and targeted capture sequencing, including bioinformatics analysis-in the context of lymphoma patient management...
October 2016: Current Oncology
https://www.readbyqxmd.com/read/27783728/social-representations-of-biosecurity-in-nursing-occupational-health-and-preventive-care
#15
Álvaro Francisco Lopes de Sousa, Artur Acelino Francisco Luz Nunes Queiroz, Layze Braz de Oliveira, Maria Eliete Batista Moura, Odinéa Maria Amorim Batista, Denise de Andrade
Objective: to understand the biosecurity social representations by primary care nursing professionals and analyze how they articulate with quality of care. Methods: exploratory and qualitative research based on social representation theory. The study participants were 36 nursing workers from primary health care in a state capital in the Northeast region of Brazil. The data were analyzed by descending hierarchical classification. Results: five classes were obtained: occupational accidents suffered by professionals; occupational exposure to biological agents; biosecurity management in primary health care; the importance of personal protective equipment; and infection control and biosecurity...
September 2016: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/27766964/adequacy-of-public-maternal-care-services-in-brazil
#16
Sonia Duarte de Azevedo Bittencourt, Rosa Maria Soares Madeira Domingues, Lenice Gnocchi da Costa Reis, Márcia Melo Ramos, Maria do Carmo Leal
BACKGROUND: In Brazil, hospital childbirth care is available to all, but differences in access and quality of care result in inequalities of maternal health. The objective of this study is to assess the infrastructure and staffing of publicly financed labor and birth care in Brazil and its adequacy according to clinical and obstetric conditions potentially associated with obstetric emergencies. METHODS: Nationwide cross-sectional hospital-based study "Birth in Brazil: national survey into labor and birth" conducted in 2011-2012...
October 17, 2016: Reproductive Health
https://www.readbyqxmd.com/read/27757191/barriers-against-implementing-blunt-abdominal-trauma-guidelines-in-a-hospital-a-qualitative-study
#17
Rouhollah Zaboli, Shahram Tofighi, Ali Aghighi, Seyyed Javad Hosaini Shokouh, Nader Naraghi, Hassan Goodarzi
INTRODUCTION: Clinical practice guidelines are structured recommendations that help physicians and patients to make proper decisions when dealing with a specific clinical condition. Because blunt abdominal trauma causes a various range of mild, single-system, and multisystem injuries, early detection will help to reduce mortality and resulting disability. Emergency treatment should be initiated based on CPGs. This study aimed to determine the variables affecting implementing blunt abdominal trauma CPGs in an Iranian hospital...
August 2016: Electronic Physician
https://www.readbyqxmd.com/read/27748306/current-costs-projected-financial-needs-of-india-s-universal-immunization-programme
#18
Susmita Chatterjee, Manish Pant, Pradeep Haldar, Mahesh Kumar Aggarwal, Ramanan Laxminarayan
BACKGROUND & OBJECTIVES: India's Universal Immunization Programme (UIP) is one of the largest programmes in the world in terms of quantities of vaccines administered, number of beneficiaries, number of immunization sessions, and geographical extent and diversity of areas covered. Strategic planning for the Programme requires credible information on the cost of achieving the objectives and the financial resources needed at national, State, and district levels. We present here expenditures on immunization services in India in 2012 (baseline) and projected costs for five years (2013-2017)...
June 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27736239/future-directions-for-clinical-research-services-and-training-evidence-based-assessment-across-informants-cultures-and-dimensional-hierarchies
#19
Thomas M Achenbach
As the Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5) acknowledges, DSM diagnostic categories do not fit the real-world heterogeneity, comorbidity, and complexity of most mental health problems. Many efforts to develop and test evidence-based treatments also fail to take account of the heterogeneity, comorbidity, and complexity of problems seen in the community settings where most mental health services are rendered. Most community services cannot attain the treatment specificity and fidelity characterizing randomized controlled trials, which often yield larger therapeutic effects than when the tested treatments are tried in community services...
October 13, 2016: Journal of Clinical Child and Adolescent Psychology
https://www.readbyqxmd.com/read/27720436/supply-chain-management-of-health-commodities-for-reducing-global-disease-burden-are-pharmacists-in-nigeria-aware-and-ready-to-play-a-key-role
#20
Otuto Amarauche Chukwu, Valentine Nnaemeka Ezeanochikwa, Benedict Ejikeme Eya
PURPOSE: Reducing global disease burden requires improving access to medicines, thus the need for efficient and effective supply chain management for medicines. The Nigerian government came up with new policies on Mega Drug Distribution Centres and National Drug Distribution Guidelines to improve access to quality medicines with pharmacists having a key role to play. However, pharmacists in Nigeria seem not to be aware and adequately equipped to handle the medicines supply chain. This article aimed at assessing the awareness and readiness of Nigerian pharmacists on supply chain management practices for improving access to medicines...
September 12, 2016: Research in Social & Administrative Pharmacy: RSAP
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