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https://www.readbyqxmd.com/read/28525513/an-observational-assessment-of-anesthesia-capacity-in-madagascar-as-a-prerequisite-to-the-development-of-a-national-surgical-plan
#1
Linden S Baxter, Vaonandianina A Ravelojaona, Hasiniaina N Rakotoarison, Alison Herbert, Emily Bruno, Kristin L Close, Vanessa Andean, Hery H Andriamanjato, Mark G Shrime, Michelle C White
BACKGROUND: The global lack of anesthesia capacity is well described, but country-specific data are needed to provide country-specific solutions. We aimed to assess anesthesia capacity in Madagascar as part of the development of a Ministry of Health national surgical plan. METHODS: As part of a nationwide surgical safety quality improvement project, we surveyed 19 of 22 regional hospitals, representing surgical facilities caring for 75% of the total population. The assessment was divided into 3 areas: anesthesia workforce density, infrastructure and equipment, and medications...
June 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28493987/barriers-to-utilization-of-childbirth-services-of-a-rural-birthing-center-in-nepal-a-qualitative-study
#2
Resham Bahadur Khatri, Tara Prasad Dangi, Rupesh Gautam, Khadka Narayan Shrestha, Caroline S E Homer
BACKGROUND: Maternal mortality and morbidity are public health problems in Nepal. In rural communities, many women give birth at home without the support of a skilled birth attendant, despite the existence of rural birthing centers. The aim of this study was to explore the barriers and provide pragmatic recommendations for better service delivery and use of rural birthing centers. METHODS: We conducted 26 in-depth interviews with service users and providers, and three focus group discussions with community key informants in a rural community of Rukum district...
2017: PloS One
https://www.readbyqxmd.com/read/28479843/usp-800-adds-significant-safety-standards-facility-upgrades-needed-to-protect-employees-from-hazardous-drugs
#3
Bruce E Beans
The new USP standard for handling hazardous drugs (HDs) will require millions of dollars in capital outlays for facility and equipment upgrades and also requires in-depth assessments of each HD that facilities handle, significant workflow and work practice changes, and thorough staff training.
May 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28459563/how-much-will-it-cost-to-monitor-microbial-drinking-water-quality-in-sub-saharan-africa
#4
Caroline Delaire, Rachel Peletz, Emily Kumpel, Joyce Kisiangani, Robert Bain, Ranjiv Khush
Microbial water quality monitoring is crucial for managing water resources and protecting public health. However, institutional testing activities in sub-Saharan Africa are currently limited. Because the economics of water quality testing are poorly understood, the extent to which cost may be a barrier to monitoring in different settings is unclear. This study used cost data from eighteen African monitoring institutions (piped water suppliers and health surveillance agencies in six countries) and estimates of water supply type coverage from fifteen countries to assess the annual financial requirements for microbial water testing at both national and regional levels, using World Health Organization recommendations for sampling frequency...
May 1, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28399707/fine-tuning-of-process-parameters-for-improving-briquette-production-from-palm-kernel-shell-gasification-waste
#5
Alireza Bazargan, Sarah L Rough, Gordon McKay
Palm kernel shell biochars (PKSB) ejected as residues from a gasifier have been used for solid fuel briquette production. With this approach, palm kernel shells can be used for energy production twice: first, by producing rich syngas during gasification; second, by compacting the leftover residues from gasification into high calorific value briquettes. Herein, the process parameters for the manufacture of PKSB biomass briquettes via compaction are optimized. Two possible optimum process scenarios are considered...
May 5, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28380265/how-do-i-participate-in-t-cell-immunotherapy
#6
REVIEW
Megan M Suhoski Davis, David H McKenna, Philip J Norris
T cells play a key role in the adaptive immune response, and the ability to manipulate T cells for therapeutic uses has advanced in the past decade. Infusion of expanded or engineered T cells can potentially be used to treat cancer, viral infections, graft-versus-host disease, and organ transplant rejection. The role that blood banks play in the manufacture and distribution of T-cell therapeutics is still being defined. Given the regulatory framework of blood banks, they are well positioned to collect raw material for manufacture of T-cell therapies and to distribute finished product to hospitals in support of clinical trials or eventually for licensed products...
May 2017: Transfusion
https://www.readbyqxmd.com/read/28372376/a-versatile-approach-to-vacuum-injection-casting-for-materials-research-and-development
#7
Donghua Xu, Yifan Xu
Vacuum injection casting (VIC) is important for research and development (R&D) of materials that are prone to oxidation at high temperatures, particularly metals and metallic alloys (e.g., metallic glasses and high entropy alloys). VIC in R&D laboratories often involves initial melting/alloying in a prior step, transporting the sample to a dedicated vacuum chamber, re-melting the sample in a quartz tube, and finally injecting the melt with an inert gas to a dedicated mold. Here we present a new approach to laboratory VIC that requires no sample transfer (for a variety of materials), no dedicated vacuum chamber/space nor dedicated mold, and hence provides more versatility and higher efficiency and yet lowers the capital equipment cost...
March 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28296438/do-group-purchasing-organizations-really-save-money-on-capital-equipment
#8
Patrick K Lynch
No abstract text is available yet for this article.
March 2017: Biomedical Instrumentation & Technology
https://www.readbyqxmd.com/read/28270259/assessment-of-the-knowledge-of-blast-injuries-management-among-physicians-working-in-tripoli-hospitals-libya
#9
Abdulhakim M Oun, Elmokhtar M Hadida, Charles Stewart
Introduction No study on hospital staff preparedness for managing blast injuries has been conducted in Libya. The internal conflict in Libya since 2011 and the difficulties faced by the hospitals has highlighted the need for such studies. Hypothesis Physicians working in Tripoli (capital city Libya) hospitals are inadequately prepared for the management of blast injuries. METHODS: A survey was conducted in all 13 hospitals in Tripoli between June 2014 and May 2015 by using interviews based on a questionnaire consisting of 29 questions covering physicians' education related to blast injury, hospital management of mass casualties, and aspects of hospital preparedness for such incidents...
March 8, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/28242974/unit-cost-analysis-of-pet-ct-at-an-apex-public-sector-health-care-institute-in-india
#10
S H Gajuryal, A Daga, V Siddharth, C S Bal, S Satpathy
CONTEXT: PET/CT scan service is one of the capital intensive and revenue-generating centres of a tertiary care hospital. The cost associated with the provisioning of PET services is dependent upon the unit costs of the resources consumed. AIMS: The study aims to determine the cost of providing PET/CT Scan services in a hospital. METHODS AND MATERIAL: This descriptive and observational study was conducted in the Department of Nuclear Medicine at a tertiary apex teaching hospital in New Delhi, India in the year 2014-15...
January 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/28220717/merger-acquisition-and-capital-expenditure-in-health-care
#11
Wenjing Ouyang, Peter E Hilsenrath
Investment, especially through merger and acquisition (M&A), is a leading topic of concern among health care managers. In addition, the implications of this activity for organization and market concentration are of great interest to policy makers. Using a sample of 2256 firm-year observations in the health care industry during the period from 1985 to 2011, this article provides novel evidence that managers learn from financial markets in making capital expenditure (CAPEX) and M&A investment decisions. Within the industry, managers in the Drugs subsector are most likely to do so, whereas managers in the Medical Equipment and Supplies are least likely to do so...
January 2017: Inquiry: a Journal of Medical Care Organization, Provision and Financing
https://www.readbyqxmd.com/read/28152680/recommendations-for-the-delivery-of-focal-tumor-ablation-services
#12
Cassandra McKay, Jonathan Wang, Fulvia Baldassarre, Amanda Wong, Deanna Langer, John Kachura, Julian Dobranowski
106 Background: The objective of this work was to develop recommendations for the organization and delivery of focal tumor ablation services. New, minimally-invasive ablation technologies such as radiofrequency ablation (RFA), microwave ablation (MWA), and transcatheter arterial chemoembolization (TACE) offer treatment options for patients with a variety of cancers. These emerging therapies can improve patient care (minimize side-effects, offer more rapid recovery with comparable or enhanced outcomes) compared to traditional approaches...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28145566/optimization-of-a-biotechnological-multiproduct-batch-plant-design-for-the-manufacture-of-four-different-products-a-real-case-scenario
#13
Gabriela Sandoval, Daniel Espinoza, Nicolas Figueroa, Juan A Asenjo
In this work a biotechnological multiproduct batch plant that manufactures four different recombinant proteins for human application is described in some detail. This batch plant design is then optimized with regards to the size of equipment using a mixed-integer linear programming (MILP) formulation recently developed by us in order to find a hypothetical new biotechnological batch plant based on the information of real known processes for the production of the four recombinant protein products. The real plant was divided for practical purposes into two sub-processes or facilities: a fermentation facility and a purification facility...
June 2017: Biotechnology and Bioengineering
https://www.readbyqxmd.com/read/28129716/potential-and-clinical-translation-of-oncolytic-measles-viruses
#14
Steven Robinson, Evanthia Galanis
Oncolytic viruses represent a novel treatment modality that is unencumbered by the standard resistance mechanisms limiting the therapeutic efficacy of conventional antineoplastic agents. Attenuated engineered measles virus strains derived from the Edmonston vaccine lineage have undergone extensive preclinical evaluation with significant antitumor activity observed in a broad range of preclinical tumoral models. These have laid the foundation for several clinical trials in both solid and hematologic malignancies, which have demonstrated safety, biologic activity and the ability to elicit antitumor immune responses...
March 2017: Expert Opinion on Biological Therapy
https://www.readbyqxmd.com/read/28117890/costs-of-food-safety-investments-in-the-meat-and-poultry-slaughter-industries
#15
REVIEW
Catherine L Viator, Mary K Muth, Jenna E Brophy, Gary Noyes
To develop regulations efficiently, federal agencies need to know the costs of implementing various regulatory alternatives. As the regulatory agency responsible for the safety of meat and poultry products, the U.S. Dept. of Agriculture's Food Safety and Inspection Service is interested in the costs borne by meat and poultry establishments. This study estimated the costs of developing, validating, and reassessing hazard analysis and critical control points (HACCP), sanitary standard operating procedures (SSOP), and sampling plans; food safety training for new employees; antimicrobial equipment and solutions; sanitizing equipment; third-party audits; and microbial tests...
February 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28116057/contrasting-behavior-between-two-populations-of-an-ice-obligate-predator-in-east-antarctica
#16
Karine Heerah, Mark Hindell, Virginia Andrew-Goff, Iain Field, Clive R McMahon, Jean-Benoît Charrassin
The Austral autumn-winter is a critical period for capital breeders such as Weddell seals that must optimize resource acquisition and storage to provision breeding in the subsequent spring. However, how Weddell seals find food in the winter months remains poorly documented. We equipped adult Weddell seals after their annual molt with satellite-relayed data loggers at two sites in East Antarctica: Dumont D'Urville (n = 12, DDU) and Davis (n = 20). We used binomial generalized mixed-effect models to investigate Weddell seals' behavioral response (i...
January 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28027164/meeting-the-needs-for-radiation-protection-diagnostic-imaging
#17
Donald P Frush
Radiation and potential risk during medical imaging is one of the foremost issues for the imaging community. Because of this, there are growing demands for accountability, including appropriate use of ionizing radiation in diagnostic and image-guided procedures. Factors contributing to this include increasing use of medical imaging; increased scrutiny (from awareness to alarm) by patients/caregivers and the public over radiation risk; and mounting calls for accountability from regulatory, accrediting, healthcare coverage (e...
February 2017: Health Physics
https://www.readbyqxmd.com/read/28024969/ultrasound-guidance-reduces-percutaneous-nephrolithotomy-cost-compared-to-fluoroscopy
#18
Matthew Hudnall, Manint Usawachintachit, Ian Metzler, David T Tzou, Brittany Harrison, Errol Lobo, Thomas Chi
OBJECTIVE: To examine the cost factors associated with ultrasound and fluoroscopic guidance for percutaneous nephrolithotomy (PCNL) and to determine which method can be performed at a lower cost per case. METHODS: A cost comparison study was performed utilizing clinical data from a prospectively maintained research database. We included the most recent 33 consecutive ultrasound-guided PCNL cases in 2016 and the most recent 40 consecutive fluoroscopy-guided PCNL cases before the operative surgeon transitioned to ultrasound guidance in May 2014...
May 2017: Urology
https://www.readbyqxmd.com/read/27990540/plasma-free-reversible-and-irreversible-microfluidic-bonding
#19
M Chu, T T Nguyen, E K Lee, J L Morival, M Khine
We demonstrate a facile, plasma free process to fabricate both reversibly and irreversibly sealed microfluidic chips using a PDMS-based adhesive polymer mixture. This is a versatile method that is compatible with current PDMS microfluidics processes. It allows for easier fabrication of multilayer microfluidic devices and is compatible with micropatterning of proteins for cell culturing. When combined with our Shrinky-Dink microfluidic prototyping, complete microfluidic device fabrication can be performed without the need for any capital equipment, making microfluidics accessible to the classroom...
December 19, 2016: Lab on a Chip
https://www.readbyqxmd.com/read/27987615/practice-patterns-of-endovenous-ablation-therapy-for-the-treatment-of-venous-reflux-disease
#20
Faisal Aziz, Jose Diaz, John Blebea, Fedor Lurie
OBJECTIVE: The purpose of this study was to assess practice patterns of endovenous ablation therapy for the treatment of venous reflux disease among the vein specialist members of the American Venous Forum (AVF). METHODS: An online survey was conducted of AVF members designed to identify demographics, treatment practices, and clinical variables in the selection of vein ablation devices. RESULTS: The survey was distributed to 798 practicing physicians, of whom 129 (16%) responded...
January 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
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