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https://www.readbyqxmd.com/read/28481257/characterisation-of-arctic-bacterial-communities-in-the-air-above-svalbard
#1
Lewis Cuthbertson, Herminia Amores-Arrocha, Lucie A Malard, Nora Els, Birgit Sattler, David A Pearce
Atmospheric dispersal of bacteria is increasingly acknowledged as an important factor influencing bacterial community biodiversity, biogeography and bacteria-human interactions, including those linked to human health. However, knowledge about patterns in microbial aerobiology is still relatively scarce, and this can be attributed, in part, to a lack of consensus on appropriate sampling and analytical methodology. In this study, three different methods were used to investigate aerial biodiversity over Svalbard: impaction, membrane filtration and drop plates...
May 6, 2017: Biology
https://www.readbyqxmd.com/read/28452604/effects-of-dexmedetomidine-on-renal-tissue-after-lower-limb-ischemia-reperfusion-injury-in-streptozotocin-induced-diabetic-rats
#2
Meral Erdal Erbatur, Şaban Cem Sezen, Aslıhan Cavunt Bayraktar, Mustafa Arslan, Mustafa Kavutçu, Muhammed Enes Aydın
AIM: The aim of this study was to investigate whether dexmedetomidine - administered before ischemia - has protective effects against lower extremity ischemia reperfusion injury that induced by clamping and subsequent declamping of infra-renal abdominal aorta in streptozotocin-induced diabetic rats. MATERIAL AND METHODS: After obtaining ethical committee approval, four study groups each containing six rats were created (Control (Group C), diabetes-control (Group DM-C), diabetes I/R (Group DM-I/R), and diabetes-I/R-dexmedetomidine (Group DM-I/R-D)...
December 2017: Libyan Journal of Medicine
https://www.readbyqxmd.com/read/28428762/gendered-pathways-how-mathematics-ability-beliefs-shape-secondary-and-postsecondary-course-and-degree-field-choices
#3
REVIEW
Lara Perez-Felkner, Samantha Nix, Kirby Thomas
Do mathematics ability beliefs explain gender gaps in the physical science, engineering, mathematics, and computer science fields (PEMC) and other science fields? We leverage U.S. nationally representative longitudinal data to estimate gendered differences in girls' and boys' perceptions of mathematics ability with the most difficult or challenging material. Our analyses examine the potentially interacting effects of gender and these ability beliefs on students' pathways to scientific careers. Specifically, we study how beliefs about ability with challenging mathematics influence girls' and boys' choices to pursue PEMC degrees, evaluating educational milestones over a 6-year period: advanced science course completion in secondary school and postsecondary major retention and selection...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28407075/once-daily-atazanavir-cobicistat-and-darunavir-cobicistat-exposure-over-72%C3%A2-h-post-dose-in-plasma-urine-and-saliva-contribution-to-drug-pharmacokinetic-knowledge
#4
Emilie R Elliot, Alieu Amara, Nicole Pagani, Laura Else, Graeme Moyle, Alex Schoolmeesters, Chris Higgs, Saye Khoo, Marta Boffito
Background: We investigated the pharmacokinetics (PK) of atazanavir/cobicistat and darunavir/cobicistat once daily over 72 h following drug intake cessation in plasma, saliva and urine. Methods: Healthy volunteers received a fixed-dose combination of 300/150 mg of atazanavir/cobicistat once daily for 10 days, followed by a 10 day washout period and then a fixed-dose combination of 800/150 mg of darunavir/cobicistat once daily for 10 days. Full PK profiles were assessed for each phase for 72 h following day 10 and parameters determined to the last measurable concentration in plasma, saliva and urine by non-compartmental methods...
April 12, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28368870/psychometric-properties-of-the-oswestry-disability-index
#5
Mikhail Saltychev, Ryan Mattie, Zachary McCormick, Esa Bärlund, Katri Laimi
The aim of this study was to investigate the psychometric properties of the Oswestry Disability Index (ODI) in a large cross-sectional cohort of individuals with chronic low back pain by defining its internal consistency, construct structure and validity, and its ability to differentiate between different degrees of functional limitation. A total of 837 consecutive outpatient patients with low back pain were studied. The internal consistency of ODI was assessed by Cronbach's α, construct structure by exploratory factor analysis, construct validity by confirmatory factor analysis, and discrimination was determined by item response theory analysis...
March 31, 2017: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
https://www.readbyqxmd.com/read/28114984/professionalism-professionalization-expertise-and-compassion-a-qualitative-study-of-medical-residents
#6
Susan P Phillips, Nancy Dalgarno
BACKGROUND: Formal and informal medical curricula convey expectations about professionalization, that is, the development of physician identity, and also about professionalism. This study examined whether, in general, junior residents experienced any dissonance between these roles and focused particularly on how they negotiated conflicts between compassion, self-care, duty and medical expertise. METHODS: In 2015, purposive sampling was used to select 21 first-year residents at a Canadian medical school...
January 23, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/27990456/an-unexpected-digital-papillary-adenocarcinoma-of-the-thumb
#7
Mitchell Nash, Juliet Burn, Simon Chan
Digital papillary adenocarcinoma (DPAca) is an aggressive lesion with high metastatic potential, which is easily misdiagnosed. We present a 55-year-old male with a cystic lesion on his right thumb. Above all else, lesions of the digits should be sent for histopathology routinely, regardless of their history or appearance.
2016: Case Reports in Plastic Surgery & Hand Surgery
https://www.readbyqxmd.com/read/27886967/the-independent-plastic-surgery-match-analysis-of-changes-in-recent-years-and-applicant-preferences
#8
Ziyad S Hammoudeh, Gamal Mostafa, Michel Saint-Cyr, Karim Bakri, Samir Mardini
BACKGROUND: The number of surgical applicants to "independent" plastic surgery programs has drastically decreased. However, the competitiveness of recent applicants relative to previous years has not been assessed. The purpose of this study was to analyze the characteristics of recent "independent" applicants and to obtain their preferences regarding the match. METHODS: A 25-question survey was distributed to 97 applicants of the 2012 "independent" match. The survey consisted of questions regarding demographics, academic qualifications, interview results, match results, program characteristic preferences, interview preferences, and future career plans...
November 2016: Journal of Surgical Education
https://www.readbyqxmd.com/read/27874118/the-influence-of-temperature-pressure-and-ag-doping-on-the-physical-properties-of-tio2-nanoceramics
#9
V H Tran, P Głuchowski, A Łukowiak, W Stre Combining Cedilla K
Undoped and Ag-doped TiO2 ceramics have been prepared at temperatures between 500-1000 °C and under pressures up to 8 GPa. Their crystal structures and physical properties were investigated by means of EDX, SEM, TEM, X-ray powder diffraction, and magnetization M, specific heat Cp and electrical resistance ρ measurements. It is found that the anatase-structured As-cast powder transforms into rutile and columbite-type at 500 °C and 5.5 GPa. The stabilization of the latter phase is fulfilled under a pressure of 8 GPa and at temperatures above 800 °C...
December 1, 2016: Nanoscale
https://www.readbyqxmd.com/read/27855394/prenasal-thickness-prefrontal-space-ratio-and-other-facial-profile-markers-in-first-trimester-fetuses-with-aneuploidies-cleft-palate-and-micrognathia
#10
Merel Bakker, Margherita Pace, Els de Jong-Pleij, Erwin Birnie, Karl-Oliver Kagan, Caterina M Bilardo
OBJECTIVE: To investigate the feasibility and reproducibility of the prenasal thickness (PNT)/nasal bone length (NBL) ratio, maxilla-nasion-mandible (MNM) angle, facial profile line, profile line distance, and prefrontal space ratio (PFSR) in the first trimester of pregnancy, develop normal ranges, and evaluate these markers in abnormal fetuses. METHODS: All measurements were performed on stored images by two operators. Feasibility, interoperator agreement, and prediction intervals were calculated for all measurements...
November 18, 2016: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/27854455/much-ado-about-nothing-capturing-attention-toward-locations-without-new-perceptual-events
#11
Matthew D Hilchey, J Eric T Taylor, Jay Pratt
Popular frameworks of attention propose that visual orienting occurs through a combination of bottom-up (stimulus-driven) and top-down (goal-directed) processes. Much of the basic research on these processes adheres paradigmatically to experimental methods that introduce salient but task-irrelevant stimuli (objects or transients) to the visual environment to determine whether attention is captured to their locations. This common practice of changing or adding a stimulus to a location to determine whether it captures attention reflects a notion that locations at which new features or stimuli spontaneously appear are prioritized above all else...
December 2016: Journal of Experimental Psychology. Human Perception and Performance
https://www.readbyqxmd.com/read/27815795/charles-william-lacaillade-biologist-parasitologist-educator-and-mentor
#12
Pascal James Imperato
Charles William Lacaillade (1904-1978) was an eminent biologist in the middle decades of the twentieth century. He was born in Lawrence, Massachusetts of parents whose ancestors were French Canadians. His father, also named Charles William Lacaillade, was a dentist who graduated from Tufts University School of Dentistry in 1898. His mother, Elodia Eno, came from a family of very successful businessmen. Lacaillade was the third of six children. His two older brothers, Harold Carleton and Hector Eno, both graduated from the University of Louisville, School of Dentistry, while his younger brother, Lawrence, became a businessman...
November 5, 2016: Journal of Community Health
https://www.readbyqxmd.com/read/27727157/brief-report-pharmacokinetic-pharmacodynamic-investigation-of-single-dose-oral-maraviroc-in-the-context-of-hiv-1-pre-exposure-prophylaxis
#13
RANDOMIZED CONTROLLED TRIAL
Julie Fox, Juan M Tiraboschi, Carolina Herrera, Laura Else, Deirdre Egan, Laura Dickinson, Akil Jackson, Natalia Olejniczak, David Back, Saye Khoo, Robin Shattock, Marta Boffito
To investigate the pharmacokinetics/pharmacodynamics of single-dose maraviroc 300 mg in HIV-1 exposure compartments. Maraviroc concentrations in blood, secretions (vaginal, urethral, oral, and rectal), and tissue (vaginal and rectal) were measured, and ex vivo challenge was performed in 54 healthy volunteers to study protection from HIV infection. Maraviroc Cmax occurred within 4 hours in most compartments. Concentrations from 4 to 72 hours were above intracellular (IC) IC90 in all compartments, range 15-8095 ng/mL...
November 1, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27687753/telehealth-monitor-to-measure-physical-activity-and-pressure-relief-maneuver-performance-in-wheelchair-users
#14
Ariel V Dowling, Valerie Eberly, Somboon Maneekobkunwong, Sara J Mulroy, Philip S Requejo, Joseph T Gwin
This study demonstrated the feasibility of a device for monitoring pressure relief maneuvers and physical activity for wheelchair users. The device counts the number of wheel pushes based on wheelchair acceleration and measures pressure relief maneuvers using a seat sensor consisting of three force sensing resistors (FSRs). To establish the feasibility of the seat sensor for the detection of pressure relief maneuvers, 10 wheelchair users and 10 non-disabled controls completed a series of wheelchair depression raises, forward trunk leans, and lateral trunk leans...
September 29, 2016: Assistive Technology: the Official Journal of RESNA
https://www.readbyqxmd.com/read/27586874/reluctance-to-retire-a-qualitative-study-on-work-identity-intergenerational-conflict-and-retirement-in-academic-medicine
#15
Michelle Pannor Silver, Sarah A Williams
PURPOSE OF THE STUDY: Some professions foster expectations that individuals cultivate their work identity above all other aspects of life. This can be problematic when individuals are confronted with the expectation that they will readily terminate this identity in later-career stages as institutions seek to cycle in new generations. This study examines the relationship between work identity and retirement by examining multiple generations of academic physicians. DESIGN AND METHODS: This study used a multimethod qualitative design that included document analysis, participant observation, focus groups, and in-depth interviews with academic physicians from one of the oldest departments of medicine in North America...
September 1, 2016: Gerontologist
https://www.readbyqxmd.com/read/27539881/the-use-of-the-soluble-adhesion-molecules-se-selectin-sicam-1-svcam-1-specam-1-and-their-ligands-cd11a-and-cd49d-as-diagnostic-and-prognostic-biomarkers-in-septic-and-critically-ill-non-septic-icu-patients
#16
Anders G Kjaergaard, Anders Dige, Jeppe S Nielsen, Else Tønnesen, Jan Krog
Endothelial activation is pivotal in the development and escalation of sepsis. Central to endothelial activation is the endothelial up-regulation of cellular adhesion molecules (CAMs) including E-selectin, ICAM-1, VCAM-1, and PECAM-1. Shed CAMs are also found in circulating soluble forms (sCAMs). We investigated whether sCAMs can be used as biomarkers for the differentiation between septic and non-septic patients. Furthermore, we investigated lymphocyte and monocyte expression of LFA-1 (CD11a/CD18) and VLA-4 (CD49d/CD29) ligands for ICAM-1 and VCAM-1, respectively...
October 2016: APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica
https://www.readbyqxmd.com/read/27251666/blood-transfusion-strategy-and-risk-of-postoperative-delirium-in-nursing-homes-residents-with-hip-fracture-a-post-hoc-analysis-based-on-the-trife-randomized-controlled-trial
#17
Sif Blandfort, Merete Gregersen, Lars Carl Borris, Else Marie Damsgaard
OBJECTIVES: To investigate whether a liberal blood transfusion strategy [Hb levels ≥11.3 g/dL (7 mmol/L)] reduces the risk of postoperative delirium (POD) on day 10, among nursing home residents with hip fracture, compared to a restrictive transfusion strategy [Hb levels ≥9.7 g/dL (6 mmol/L)]. Furthermore, to investigate whether POD influences mortality within 90 days after hip surgery. METHODS: This is a post hoc analysis based on The TRIFE - a randomized controlled trial...
June 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/27233840/flexible-dual-form-nicotine-replacement-therapy-or-varenicline-in-comparison-with-nicotine-patch-for-smoking-cessation-a-randomized-controlled-trial
#18
RANDOMIZED CONTROLLED TRIAL
Heather E Tulloch, Andrew L Pipe, Charl Els, Matthew J Clyde, Robert D Reid
BACKGROUND: Extended use of combined pharmacotherapies to treat tobacco dependence may increase smoking abstinence; few studies have examined their effectiveness. The objective of this study was to evaluate smoking abstinence with standard nicotine patch (NRT), extended use of combined formulations of nicotine replacement therapy (NRT+), or varenicline (VR). METHODS: A total of 737 smokers, including those with medical and psychiatric comorbidities, were randomly assigned to one of the above three treatment conditions...
June 7, 2016: BMC Medicine
https://www.readbyqxmd.com/read/27207635/the-thermal-dependence-of-na-flux-in-isolated-liver-cells-from-ectotherms-and-endotherms
#19
Paul L Else
The thermal dependence (0-40°C) of Na(+) flux in isolated liver cells of three endotherms (mice, rat and rabbit) was compared with that of ectotherms in the form of a thermally tolerant amphibian (cane toad), a cold-water fish (rainbow trout) and a thermophilic reptile (lizard). Mammals were found to share similar high rates of Na(+) flux (3.0-3.7 nmol Na(+) mg(-1) protein min(-1)) at their normal body temperatures (36-39°C). These Na(+) flux rates were significantly greater (P<0.0004-0.0001) than those of the ectotherms, which shared similar low rates of Na(+) flux (0...
July 15, 2016: Journal of Experimental Biology
https://www.readbyqxmd.com/read/27047719/fpga-implemented-testbed-in-8-by-8-and-2-by-2-ofdm-mimo-channel-estimation-and-design-of-baseband-transceiver
#20
S Ramesh, R Seshasayanan
In this study, a baseband OFDM-MIMO framework with channel timing and estimation synchronization is composed and executed utilizing the FPGA innovation. The framework is prototyped in light of the IEEE 802.11a standard and the signals transmitted and received utilizing a data transmission of 20 MHz. With the assistance of the QPSK tweak, the framework can accomplish a throughput of 24 Mbps. Besides, the LS formula is executed and the estimation of a frequency-specific fading channel is illustrated. For the rough estimation of timing, MNC plan is examined and actualized...
2016: SpringerPlus
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