Mikko Petteri Räisänen, Olli V Leppänen, Janne Soikkeli, Aleksi Reito, Antti Malmivaara, Rachelle Buchbinder, Hannu Kautiainen, Antti Kaivorinne, Susanna Stjernberg-Salmela, Minna Lappalainen, Toni Luokkala, Annele Pönkkö, Hanna-Stiina Taskinen, Markus Pääkkönen, Kati Jaatinen, Joona Juurakko, Venla-Linnea Karjalainen, Teemu Karjalainen
BACKGROUND: Surgery, needle fasciotomy, and collagenase injection are used to treat Dupuytren contracture. The treatment decision requires balancing initial morbidity and costs of surgery against its potential long-term benefits over needle fasciotomy and collagenase. OBJECTIVE: To compare the effectiveness of surgery, needle fasciotomy, and collagenase injection at 3 months and 2 years (secondary time points of the trial). DESIGN: A multicenter, randomized, outcome assessor-blinded, superiority trial...
February 13, 2024: Annals of Internal Medicine