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https://www.readbyqxmd.com/read/28074415/proceedings-of-r%C3%A3-animation-2017-the-french-intensive-care-society-international-congress
#1
Wulfran Bougouin, Eloi Marijon, Benjamin Planquette, Nicole Karam, Florence Dumas, David Celermajer, Daniel Jost, Lionel Lamhaut, Frankie Beganton, Alain Cariou, Guy Meyer, Xavier Jouven, Côme Bureau, Julien Charpentier, Omar Ben Hadj Salem, Lucie Guillemet, Michel Arnaout, Alexis Ferre, Guillaume Geri, Nicolas Mongardon, Frédéric Pène, Jean-Daniel Chiche, Jean-Paul Mira, Guylaine Labro, François Belon, Vinh-Phuc Luu, Julien Chenet, Guillaume Besch, Marc Puyraveau, Gaël Piton, Gilles Capellier, Maëlle Martin, Jean-Baptiste Lascarrou, Aurélie Le Thuaut, Jean-Claude Lacherade, Laurent Martin-Lefèvre, Maud Fiancette, Isabelle Vinatier, Christine Lebert, Konstantinos Bachoumas, Aihem Yehia, Matthieu Henry-Laguarrigue, Gwenhaël Colin, Jean Reignier, Elodie Privat, Joséphine Escutnaire, Cyrielle Dumont, Valentine Baert, Christian Vilhelm, Hervé Hubert, Vincent Robert-Edan, Karim Lakhal, Andrew Quartin, Brian Hobbs, Cynthia Cely, Cynthia Bell, Tai Pham, Roland Schein, Yimin Geng, Chaan Ng, Stephan Ehrmann, Charlotte Salmon Gandonnière, Julie Boisramé-Helms, Olivier Le Tilly, Isabelle Benz De Bretagne, Emmanuelle Mercier, Julie Mankikian, Anne Bretagnol, Ferhat Meziani, Jean Michel Halimi, Chantal Barin Le Guellec, Stéphane Gaudry, David Hajage, Florence Tubach, Bertrand Pons, Eric Boulet, Alexandre Boyer, Guillaume Chevrel, Nicolas Lerolle, Dorothée Carpentier, Nicolas de Prost, Alexandre Lautrette, Julien Mayaux, Saad Nseir, Jean-Damien Ricard, Didier Dreyfuss, René Robert, Franscesco Garzotto, Eric Kipnis, Ciro Tetta, Claudio Ronco, David Schnell, Bourmaud Aurelie, Marie Reynaud, Christophe Clec'h, Mourad Benyamina, François Vincent, Christophe Mariat, Caroline Bornstain, Stephane Rouleau, Christophe Leroy, Yves Cohen, Jerome Morel, Matthieu Legrand, Jeremy Terreaux, Michaël Darmon, Marie Cantier, Adeline Morisot, Emmanuel Guérot, Emmanuel Canet, Etienne De Montmollin, Guillaume Voiriot, Mathilde Neuville, Jean-François Timsit, Romain Sonneville, Abdallah Fayssoil, Tania Stojkovic, Anthony Behin, Adam Ogna, Frédéric Lofaso, Pascal Laforet, Karim Wahbi, Helene Prigent, Denis Duboc, David Orlikowski, Bruno Eymard, Djillali Annane, Loic Le Guennec, Clémentine Cholet, Nicolas Bréchot, Guillaume Hekimian, Sébastien Besset, Guillaume Lebreton, Ania Nieszkowska, Jean Louis Trouillet, Pascal Leprince, Alain Combes, Charles-Edouard Luyt, Marion Griton, Musa Sesay, Nadia Sibaï De Panthou, Thomas Bienvenu, Matthieu Biais, Karine Nouette-Gaulain, Guillaume Fossat, Florian Baudin, Cécile Coulanges, Sabrine Bobet, Arnaud Dupont, Léa Courtes, Dalila Benzekri, Toufik Kamel, Grégoire Muller, Nicolas Bercault, François Barbier, Isabelle Runge, Marie Skarzynski, Armelle Mathonnet, Thierry Boulain, Youenn Jouan, Noémie Teixera, Claire Hassen-Khodja, Antoine Guillon, Christophe Gaborit, Leslie Grammatico-Guillon, Cécile Rebière, Elie Azoulay, Benoit Misset, Stephane Ruckly, Maïté Garrouste-Orgeas, Nancy Kentish-Barnes, Jacques Duranteau, Marie Thuong, Liliane Joseph, Anne Renault, Olivier Lesieur, Anne-Gaelle Si Larbi, Gérald Viquesnel, Benjamin Zuber, Sophie Marque, Stanislas Kandelman, Nicolas Pichon, Bernard Floccard, Marion Galon, Sylvie Chevret, Nancy Kentish-Barnes, Valérie Seegers, Stéphane Legriel, Samir Jaber, Jean Yves Lefrant, Danielle Reuter, Olivier Guisset, Christophe Cracco, Amélie Seguin, Jacques Durand-Gasselin, Marine Thirion, Zoé Cohen-Solal, Hélène Foulgoc, Julien Rogier, Elsa Delobbe, Frédérique Schortgen, Pierre Asfar, Boisramé-Helms Julie, David Grimaldi, Grelon Fabien, Nadia Anguel, Lasocki Sigismond, Henry-Lagarrigue Matthieu, Frédéric Gonzalez, Legay François, Christophe Guitton, Maleka Schenck, Doise Jean-Marc, Peter Radermacher, Nancy Kentish-Barnes, Joseph Nsiala Makunza, Mejeni Kamdem Nathalie, Akilimali Pierre, Kilembe Manzanza Adolphe, Rafael Mahieu, Thomas Reydel, Angéline Jamet, Nicolas Chudeau, Julien Huntzinger, Steven Grange, Anne Courte, Jérémie Lemarie, Sébastien Gibot, Julia Champey, Jean Dellamonica, Damien Du Cheyron, Damien Contou, Jean-Marc Tadié, Martin Cour, Gaetan Beduneau, Antoine Marchalot, Laurent Guérin, Sebastien Jochmans, Nicolas Terzi, Sebastien Preau, Christian Brun-Buisson, Armand Mekontso Dessap, Meryl Vedrenne-Cloquet, Sophie Breinig, Camille Jung, Maxime Brussieux, Marie-Odile Marcoux, Xavier Durrmeyer, Renaud Blondé, François Angoulvant, Jérôme Grasset, Jérôme Naudin, Stéphane Dauger, Solenn Remy, Karine Kolev-Descamp, Julie Demaret, Guillaume Monneret, Etienne Javouhey, Maryline Chomton, Michaël Sauthier, Emilie Vallieres, Philippe Jouvet, Guillaume Geslain, Isabelle Guellec, Jérôme Rambaud, Matthieu Schmidt, Peter Schellongowski, Amandine Dorget, Nicolo Patroniti, Fabio Silvio Taccone, Dinis Reis Miranda, Jean Reuter, Hélène Prodanovic, Marc Pierrot, Martin Balik, Sunghoon Park, Claude Guérin, Laurent Papazian, Reignier Jean, Louis Ayzac, Anderson Loundou, Jean-Marie Forel, Mehdi Mezidi, Mylène Aublanc, Sophie Perinel-Ragey, Floriane Lissonde, Aurore Louf-Durier, Romain Tapponnier, Hodane Yonis, Remi Coudroy, Jean-Pierre Frat, Florence Boissier, Arnaud W Thille, Flore Richard, Hélène Le Gullou-Guillemette, Jonathan Fahri, Achille Kouatchet, Laetitia Bodet-Contentin, Denis Garot, Déborah Le Pennec, Laurent Vecellio, Elsa Tavernier, Pierre François Dequin, Jonathan Messika, Yolaine Martin, Natacha Maquigneau, Christelle Puechberty, Annabelle Stoclin, Serge Villard, Aline Dechanet, Audrey De Jong, Marion Monnin, Mehdi Girard, Gérald Chanques, Nicolas Molinari, Maxens Decavèle, Sébastien Campion, Roukia Ainsouya, Marie-Cécile Niérat, Mathieu Raux, Thomas Similowski, Alexandre Demoule, Keyvan Razazi, Martial Tchir, Faten May, Guillaume Carteaux, Rougevin-Baville Pauline, Andronikof Marc, Jean Pierre Bedos, Koukabi Mehrsa, Carole Mauger-Briche, François Mijon, Pierre Trouiller, Benjamin Sztrymf, Pierre Cretallaz, Romain Mermillod-Blondin, Dominique Savary, Ines Sedghiani, Hamdi Doghri, Asma Jendoubi, Dhekra Hamdi, Mohamed Ali Cherif, Youssef Zied El Hechmi, Jerbi Zouheir, Nicolas Persico, Francois Maltese, Cécile Ferrigno, Amandine Bablon, Cécile Marmillot, Antoine Roch, Ines Sedghiani, Grégory Papin, Marc Gainnier, Laurent Argaud, Adrie Christophe, Bertrand Souweine, Dany Goldgran-Toledano, Guillaume Marcotte, Anne Sylvie Dumenil, Schwebel Carole, Jerôme Cecchini, Samuel Tuffet, Muriel Fartoukh, Damien Roux, Martial Thyrault, Mekontso Dessap Armand, Simon Chauveau, Nadège Wesner, Laurence Monnier-Cholley, Naïke Bigé, Hafid Ait-Oufella, Bertrand Guidet, Vincent Dubée, Pierre Labroca, Jérémie Lemarié, Gérard Chiesa, Isabelle Laroyenne, Léo Borrini, Rémi Klotz, Quoc Phan Sy, Marie-Christine Cristina, Jean Paysant, Pierre Fillâtre, Arnaud Gacouin, Matthieu Revest, Pierre Tattevin, Erwan Flecher, Yves Le Tulzo, Matthieu Jamme, Fabrice Daviaud, Nathalie Marin, Michael Thy, Baptiste Duceau, Fanny Ardisson, Valade Sandrine, Marion Venot, Benoît Schlemmer, Lara Zafrani, Stéphanie Pons, Lenka Styfalova, Lila Bouadma, Aguila Radjou, Jordane Lebut, Bruno Mourvillier, Richard Dorent, Marie-Pierre Dilly, Patrick Nataf, Michel Wolff, Aëlle Le Gall, Simon Bourcier, Yacine Tandjaoui-Lambiotte, Vincent Das, Mikael Alves, Naïke Bigé, Chtara Kamilia, Ammar Rania, Najeh Baccouch, Olfa Turki, Hmida Chokri Ben, Mabrouk Bahloul, Mounir Bouaziz, Claire Dupuis, Anne Perozziello, Julien Letheulle, Marc Valette, Cécile Herrmann-Storck, Laura Crosby, Khalid Elkoun, Benjamin Madeux, Frédéric Martino, Hélène Migueres, Pascale Piednoir, Matthias Posch, Guillaume Thiery, Minh-Tu Huynh-Ky, Pierre Alexandre Bouchard, Jean-François Sarrazin, François Lellouche, Mai-Anh Nay, Brice Lortat-Jacob, Bertrand Rozec, Marion Colnot, Nicolas Belin, Loïc Barrot, Jean-Christophe Navellou, Cyrille Patry, Claire Chaignat, Melanie Claveau, Frédéric Claude, Cécile Aubron, Zoe Mcquilten, Michael Bailey, Jasmin Board, Heidi Buhr, Bruce Cartwright, Mark Dennis, Paul Forrest, Carol Hodgson, David Mcilroy, Deirdre Murphy, Lynnette Murray, Vincent Pellegrino, David Pilcher, Jayne Sheldrake, Huyen Tran, Shirley Vallance, Jamie Cooper, Camille Bombled, Charles Vidal, Dimitri Margetis, Julien Amour, Domien Coart, Jasperina Dubois, Tom Van Herpe, Dieter Mesotten, Sébastien Bailly, Jc Lucet, Alain Lepape, François L'hériteau, Martine Aupée, Caroline Bervas, Sandrine Boussat, Anne Berger-Carbonne, Anaïs Machut, Anne Savey, Jean-Jacques Tudesq, Sandrine Valade, Lionel Galicier, Cédric De Bazelaire, Nicolas Munoz-Bongrand, Xavier Mignard, Lucie Biard, Djamel Mokart, Martine Nyunga, Fabrice Bruneel, Antoine Rabbat, Pierre Perez, Anne Pascale Meert, Dominique Benoit, Eric Mariotte, Franck Ehooman, Rebecca Hamidfar-Roy, Yannick Hourmant, Arnaud Mailloux, Alexandra Beurton, Jean-Louis Teboul, Valentina Girroto, Galarza Laura, Christian Richard, Xavier Monnet, Vincent Dubée, Hamid Merdji, Julien Dang, Gabriel Preda, Jean-Luc Baudel, Cyrielle Desnos, Michel Zeitouni, Ines Belaroussi, Antoine Parrot, Clarisse Blayau, Jean-Pierre Fulgencio, Christophe Quesnel, Vincent Labbe, Marc Pineton De Chambrun, François Beloncle, Sybille Merceron, Yannick Fedun, Bernard Lecomte, Jérôme Devaquet, Marc Puidupin, Bruno Verdière, Zahir Amoura, Constance Vuillard, Jais Xavier, Delphine Bourlier, Amar David, Sattler Caroline, Montani David, Simmoneau Gerald, Sitbon Olivier, Marc Humbert, Savale Laurent, Olivier Dujardin, Adrien Bouglé, Hamou Nora Ait, Joe Elie Salem, Najoua El-Helali, Zoé Coppere, Aude Gibelin, Clementine Taconet, Michel Djibre, Adel Maamar, Elen Colobert, Pierre Fillatre, Fabrice Uhel, Christophe Camus, Josquin Moraly, Redouane Dahoumane, Eric Maury, Boun Kim Tan, Vivier Emmanuel, Misslin Pauline, Parmeland Laurence, Poirié Philippe, Jean-Ralph Zahar, Haond Catherine, Pommier Christian, Ait-Bouziad Karim, Hocine Mounia, Témime Laura, Vero Hanitra Rasoldier, Guy Mager, Jean-Pierre Eraldi, Stéphanie Gelinotte, François Bougerol, Julien Dehay, Jean-Philippe Rigaud, Pierre Louis Declercq, Julien Michel, Nejla Aissa, Sandrine Henard, Philippe Guerci, Ichraq Latar, Bruno Levy, Nicolas Girerd, Antoine Kimmoun, Saousen Ben Abdallah, Sabrine Nakaa, Kmar Hraiech, Dhouha Ben Braiek, Ali Adhieb, Abdelwaheb M'ghirbi, Ali Ousji, Zeineb Hammouda, Fekri Abroug, Walid Sellami, Zied Hajjej, Walid Samoud, Iheb Labbene, Mustapha Ferjani, Fatma Kaaniche Medhioub, Rania Allela, Najla Ben Algia, Samar Cherif, Delphine Attia, Andrianjafy Herinjatovo, Xavier Laborne Francois, Med Aziz Bouhouri, Mohamed Taoufik Slaoui, A Soufi, K Khaleq, D Hamoudi, A Nsiri, R Harrar, Eric Maury, Suzanne Goursaud, Maxime Gauberti, Paul-Emile Labeyrie, Thomas Gaberel, Véronique Agin, Eric Maubert, Denis Vivien, Clément Gakuba, Anwar Armel, Rchi Abdou, Samira Kalouch, Khalid Yaqini, Aziz Chlilek, Walid Sellami, Soumaya Ben Yedder, Alexandre Tonnelier, Fabien Hervé, Guillaume Halley, Jean-Luc Frances, Mickael Moriconi, Mathieu Saoli, Aude Garnero, Didier Demory, Jean Michel Arnal, Bertrand Canoville, Cédric Daubin, Jennifer Brunet, Hassen Ben Ghezala, Salah Snouda, Chiekh Imen Ben, Moez Kaddour, Islem Ouanes, Mahdi Marzouk, Françoise Haniez, Hélène Jaillet, Henri Maas, Pierre Andrivet, Christian Darné, François Viau, Hassen Ben Ghezala, Islem Ouanes, Laurence Dangers, Claire Montlahuc, Sébastien Perbet, Islem Ouanes, Zeineb Hamouda, Sabrine Nakee, Lamia Ouanes-Besbes, Khaoula Meddeb, Ahmed Khedher, Nesrine Sma, Jihene Ayachi, Messaouda Khelfa, Nesrine Fraj, Hend Ben Lakhal, Hedia Hammed, Raja Boukadida, Hajer Hafsa, Imed Chouchene, Mohamed Boussarsar, Braiek Dhouha Ben, Lamia Ouanes-Besbes, Kaoutar Benatti, A Dafir, W Aissaoui, W Elallame, W Haddad, R Cherkab, C Elkettani, L Barrou, Zakaria Ait Hamou, Xavier Repessé, Cyril Charron, Alix Aubry, Alexis Paternot, Julien Maizel, Michel Slama, Antoine Vieillard-Baron, Ahlem Trifi, Sami Abdellatif, Meriem Fatnassi, Foued Daly, Rochdi Nasri, Khaoula Ben Ismail, Salah Ben Lakhal, Florian Bazalgette, Aurelien Daurat, Claire Roger, Laurent Muller, Denis Doyen, Rémi Plattier, Alexandre Robert, Hervé Hyvernat, Gilles Bernardin, Mathieu Jozwiak, Julia Gimenez, Pablo Mercado, François Depret, Najla Tilouch, Houda Mater, Ben Sik Ali Habiba, Oussama Jaoued, Rim Gharbi, Mohamed Fekih Hassen, Souheil Elatrous, Pierre Pasquier, Quentin Vuillemin, Jean-Vivien Schaal, Thibault Martinez, Sandrine Duron, Marion Trousselard, Pierre-Eric Schwartzbrod, Thomas Baugnon, Laurent Dupic, Caroline Duracher Gout, Laure De Saint Blanquat, Sylvie Séguret, Gaelle Le Ficher, Gilles Orliaguet, Philippe Hubert, Naïke Bigé, Guillaume Leblanc, Raphael Briand, Lucas Brousse, Valentine Brunet, Léonard Chatelain, Dominique Prat, Frédéric Jacobs, Nadège Demars, Olfa Hamzaoui, Guy Moneger, Benjamin Sztrymf, Emilie Duburcq-Gury, Léa Satre-Buisson, Thibault Duburcq, Julien Poissy, Laurent Robriquet, Merce Jourdain, Thierry Sécheresse, Mattéo Miquet, Alexis Simond, Pascal Usseglio, Yamina Hamdaoui, Mohamed Boussarsar, Victoire Desailly, Patrick Brun, Pauline Iglesias, Jérémie Huet, Clémence Masseran, Antoine Claudon, Clément Ebeyer, Thomas Truong, Antoine Tesnière, Alexandre Mignon, Stéphane Gaudry, Dabor Resiere, Ruddy Valentino, Julien Fabre, Benoit Roze, Jean-Louis Ferge, Cyrille Charbatier, Sabia Marie, Michel Scholsser, Signate Aitsatou, Mathieu Raad, Andre Cabie, Hossein Mehdaoui, Clement Cousin, Christophe Rousseau, Jean-François Llitjos, Fanny Alby-Laurent, Julie Toubiana, Nadia Belaidouni, Marlène Cherruault, Jérome Tamburini, Didier Bouscary, Sarah Fert, Eugénie Delile, Emmanuel Besnier, David Coquerel, Rémi Nevière, Vincent Richard, Fabienne Tamion, Chaojie Wei, Huguette Louis, Schmitt Margaux, Albuisson Eliane, Orlowski Sophie, Antoine Kimmoun, Zakaria Riad, Marine Coroir, Bernard Rémy, Bombled Camille, Jeremie Joffre, Philippe Aegerter, Dejan Ilic, Marc Ginet, Caroline Pignard, Philippe Nguyen, Guillaume Mourey, Emmanuel Samain, Sebastien Pili-Floury, Romain Jouffroy, Caill Nicolas, Jean-Claude Alvarez, Maraffi Tomasso, Pascal Philippe, Jean-Herlé Raphalen, J Baud Frédéric, Benoit Vivien, Carli Pierre, Frederic Baud, Hana Fredj, Youssef Blel, Nozha Brahmi, Hassen Ben Ghezala, Anne-Sophie Hanak, Isabelle Malissin, Joel Poupon, Patricia Risede, Lucie Chevillard, Bruno Megarbane, Manel Barghouth, Aymen M'rad, Marwa Ben Hmida, Hafedh Thabet, Hao Liang, Jacques Callebert, Camille Lagard, Bruno Megarbane, Sahar Habacha, Bassem Chatbri, Christophe Camillerapp, Laurence Labat, Marion Soichot, Pierre Garçon, Antoine Goury, Lamia Kerdjana, Sebastian Voicu, Nicolas Deye, Bruno Megarbane, Anwar Armel, Benqqa Anas, Mezgui Othman, S Moumine, S Kalouch, K K Yakini, A Chlilek, Ahmed Hajji, Assaad Louati, Ammar Khaldi, Aida Borgi, Nargess Ghali, Asma Bouziri, Khaled Menif, Jaballah Najla Ben, Anwar Armel, Jeanne Brochon, Mihaela Dumitrescu, Sarah Thévenot, Jean-Pascal Saulnier, Khaled Husseini, Catherine Laland, Julie Cremniter, Anne Bousseau, Olivier Castel, Cassandra Brémaud-Csizmadia, Margot Diss, Aurélie Portefaix, Julien Berthiller, Yves Gillet, Nabil Tabet Aoul, Ali Douah, Zakaria Addou, Houari Youbi, Mohamed Moussati, Kamel Belhabiche, Souad Mir, Sanaa Abada, Zerhouni Amel, Nabil Aouffen, Zina Bouzit, Ahmed H Grati, Gilles F Dhonneur, Mohamed Boussarsar, Nicolas Lau, Ilham Mezhari, Nicolas Roucaud, Matthieu Le Meur, Rémi Paulet, Jean-Michel Coudray, Wahiba Imène Ghomari, Reda Boumlik, Vincent Peigne, Jean-Louis Daban, Mathieu Boutonnet, Bernard Lenoir, Hafiani Yassine, Cheikh Chaigar Mohamed, Allali Khalid, Moussaid Ihssan, Elyoussoufi Said, Salmi Said, Amira Ben Jazia, Jaziri Fatima, Skouri Wafa, Bennasr Maha, Ben Abdelghni Khaoula, Turki Sami, B Abdallah Taeib, Fatma Kaaniche Medhioub, Virginie Rollet-Cohen, Philippe Sachs, Zied Merchaoui, Sylvain Renolleau, Mehdi Oualha, Maxime Eloi, Sandrine Jean, Maryne Demoulin, Cécile Valentin, Julia Guilbert, Hervé Walti, Ricardo Carbajal, Pierre-Louis Leger, Yasemin Karaca-Altintas, Astrid Botte, Julien Labreuche, Elodie Drumez, Patrick Devos, Franck Bour, Francis Leclerc, Ayari Ahmed, Menif Khaled, Assaad Louati, Borgi Aida, Khaldi Ammar, Ghali Narjess, Hajji Ahmed, Bouziri Asma, Nejla Ben Jaballah, Pierre-Louis Leger, Julien Pansiot, Valérie Besson, Bruno Palmier, Olivier Baud, Bruno Cauli, Christiane Charriaut-Marlangue, Amélie Mansuy, Fabrice Michel, Stéphane Le Bel, Julia Boubnova, Fabrice Ughetto, Caroline Ovaert, Virginie Fouilloux, Olivier Paut, Matthias Jacquet-Lagrèze, Nicolas Tiebergien, Najib Hanna, Jean-Noël Evain, Florent Baudin, Sonia Courtil-Teyssedre, Dominique Bompard, Marc Lilot, Laurent Chardonal, Jean-Luc Fellahi, Claire Claverie, Guillaume Pouessel, Aimée Dorkenoo, Jean-Marie Renaudin, Mireille Eb, Antoine Deschildre, Stéphane Leteurtre, Hafiani Yassine, Belkadi Kamal, Oboukhlik Adil, Aalalam Ouafa, Moussaoui Mouhamed, Charkab Rachid, Barrou Lahoucine, Fahmi Dachraoui, Sabrine Nakkaa, Hammouda Zaineb, Dorra Mlika, Olfa Gloulou, Mohamed Boussarsar, Setti-Aouicha Zelmat, Djamila-Djahida Batouche, Belkacem Chaffi, Fatima Mazour, Nadia Benatta, Ines Fathallah, Rafaa Aloui, Aymen Zoubli, Nadia Kouraichi, Ines Fathallah, N Kouraichi, Shireen Salem, Eric Vicaut, Bruno Megarbane, David Ambroise, Anne-Marie Loriot, Emmanuel Bourgogne, Bruno Megarbane, Hatem Ghadhoune, Guissouma Jihene, Insaf Trabelsi, Hend Allouche, Habib Brahmi, Mohamed Samet, Hatem El Ghord, Rodolphe Lebeau, Jean-Louis Laplanche, Nadia Benturquia, Bruno Megarbane, Youssef Blel, A M'rad, Fatma Essafi, A Benabderrahim, Romain Jouffroy, Dabor Resiere, Bruno Sanchez, Jocelyn Inamo, Bruno Megarbane, Djamila-Djahida Batouche, Amel Zerhouni, Kheira Tabeliouna, Amine Negadi, Zahia Mentouri, Fanny Le Gall, Jean-Luc Hanouz, Hervé Normand, Abdo Khoury, Fatimata Seydou Sall, Alban De Luca, Aurore Pugin, Lionel Pazart, Chrystelle Vidal, Franck Leroux, Abdo Khoury, Erwan L'Her, Nicolas Marjanovic, Abdo Khoury, Thibault Desmettre, Christophe Lambert, Sophie Perinel Ragey, Loredana Baboi, Jean-Etienne Bazin, Catherine Koffel, Gilles Dhonneur, Zina Bouzit, Larbi Bradai, Issam Ben Ayed, Fethi Aissa, Hakim Haouache, Yoann Marechal, Patrick Biston, Michael Piagnerelli, Perrine Bortolotti, Delphine Colling, Vincent Colas, Benoit Voisin, Florent Dewavrin, Thierry Onimus, Patrick Girardie, Fabienne Saulnier, Tomas Urbina, Yann Nguyen, Anne-Lise Druoton, Marc Soudant, Damien Barraud, Marie Conrad, Aurélie Cravoisy-Popovic, Lionel Nace, Pierre-Edouard Bollaert, Ruste Martin, Laurent Bitker, Jean-Christophe Richard, David Brossier, Isabelle Goyer, Christopher Marquis, Marie Lampin, Alain Duhamel, Hélène Béhal, Tahar Dhaoui, Véronique Godeffroy, Eve Devouge, Dominique Evrard, Florence Delepoulle, Sylvie Racoussot, Bruno Grandbastien, Marie Lampin, Claire Heilbronner, Emeline Roy, Alexandra Masson, Alice Hadchouel-Duvergé, Virginie Rigourd, Elise Delacroix, Isabelle Wroblewski, Isabelle Pin, Anne Ego, Valerie Payen, Thierry Debillon, Anne Millet, Julien Denot, Véronique Berthelot, Emilie Thueux, Marie Reymond, Alexandra De Larrard, Alain Amblard, Pierre-Louis Leger, Nabil Tabet Aoul, Virginie Lemiale, Johanna Oziel, Noelle Brule, Anne-Sophie Moreau, Takoua Marhbène, Salma Sellami, Amira Jamoussi, Samia Ayed, Emna Mhiri, Leila Slim, Jalila Ben Khelil, Mohamed Besbes, Sylvain Chawki, Aicha Hamdi, Magali Ciroldi, Alice Cottereau, Edouard Obadia, Yoann Zerbib, Claire Andrejak, Sylvie Ricome, Hervé Dupont, François Baudin, Pauline Dureau, Audrey Tanguy, Charlotte Arbelot, Hassen Kais Ben, Ahmed Charfeddine, Benjamin Granger, Lucile Laporte, Coralie Hermetet, Kais Regaieg, Rim Khemakhem, Hedi Chelly, Chaigar Mohammed Cheikh, Hamid Mountij, Kawtar Rghioui, Wafae Haddad, Rachid Cherkab, Houcine Barrou, Aitmouden Naima, Othmani M Bennani, Kais Regaieg, Ahmed Douib, Amal Samet, Pierre-Julien Cungi, Cédric Nguyen, Jean Cotte, Erwan D'aranda, Eric Meaudre, Jean-Phillipe Avaro, Mohamed Taoufik Slaoui, Amel Mokline, Imene Rahmani, Achraf Laajili, Helmi Amri, Lazheri Gharsallah, Bahija Gasri, Sofiene Tlaili, Rym Hammouda, Amen Allah Messadi
No abstract text is available yet for this article.
January 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28031221/molecular-magnetic-resonance-imaging-discloses-endothelial-activation-after-transient-ischaemic-attack
#2
Aurélien Quenault, Sara Martinez de Lizarrondo, Olivier Etard, Maxime Gauberti, Cyrille Orset, Benoît Haelewyn, Helen C Segal, Peter M Rothwell, Denis Vivien, Emmanuel Touzé, Carine Ali
SEE SUN ET AL DOI101093/AWW306 FOR A SCIENTIFIC COMMENTARY ON THIS ARTICLE: About 20% of patients with ischaemic stroke have a preceding transient ischaemic attack, which is clinically defined as focal neurological symptoms of ischaemic origin resolving spontaneously. Failure to diagnose transient ischaemic attack is a wasted opportunity to prevent recurrent disabling stroke. Unfortunately, diagnosis can be difficult, due to numerous mimics, and to the absence of a specific test. New diagnostic tools are thus needed, in particular for radiologically silent cases, which correspond to the recommended tissue-based definition of transient ischaemic attack...
January 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/27709777/valproic-acid-a-relevant-thromboprophylactic-strategy
#3
S Martinez de Lizarrondo, M Gauberti, D Vivien
No abstract text is available yet for this article.
December 2016: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/27531677/hyperfibrinolysis-increases-blood-brain-barrier-permeability-by-a-plasmin-and-bradykinin-dependent-mechanism
#4
Oscar A Marcos-Contreras, Sara Martinez de Lizarrondo, Isabelle Bardou, Cyrille Orset, Mathilde Pruvost, Antoine Anfray, Yvann Frigout, Yannick Hommet, Laurent Lebouvier, Joan Montaner, Denis Vivien, Maxime Gauberti
Hyperfibrinolysis is a systemic condition occurring in various clinical disorders such as trauma, liver cirrhosis, and leukemia. Apart from increased bleeding tendency, the pathophysiological consequences of hyperfibrinolysis remain largely unknown. Our aim was to develop an experimental model of hyperfibrinolysis and to study its effects on the homeostasis of the blood-brain barrier (BBB). We induced a sustained hyperfibrinolytic state in mice by hydrodynamic transfection of a plasmid encoding for tissue-type plasminogen activator (tPA)...
November 17, 2016: Blood
https://www.readbyqxmd.com/read/27032444/efficacy-of-alteplase-in-a-mouse-model-of-acute-ischemic-stroke-a-retrospective-pooled-analysis
#5
Cyrille Orset, Benoit Haelewyn, Stuart M Allan, Saema Ansar, Francesco Campos, Tae Hee Cho, Anne Durand, Mohamad El Amki, Marc Fatar, Isaac Garcia-Yébenes, Maxime Gauberti, Saskia Grudzenski, Ignacio Lizasoain, Eng Lo, Richard Macrez, Isabelle Margaill, Samaneh Maysami, Stephen Meairs, Norbert Nighoghossian, Josune Orbe, Jose Antonio Paramo, Jean-Jacques Parienti, Nancy J Rothwell, Marina Rubio, Christian Waeber, Alan R Young, Emmanuel Touzé, Denis Vivien
BACKGROUND AND PURPOSE: The debate over the fact that experimental drugs proposed for the treatment of stroke fail in the translation to the clinical situation has attracted considerable attention in the literature. In this context, we present a retrospective pooled analysis of a large data set from preclinical studies, to examine the effects of early versus late administration of intravenous recombinant tissue-type plasminogen activator. METHODS: We collected data from 26 individual studies from 9 international centers (13 researchers; 716 animals) that compared recombinant tissue-type plasminogen activator with controls, in a unique mouse model of thromboembolic stroke induced by an in situ injection of thrombin into the middle cerebral artery...
May 2016: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/27022410/nano-zymography-using-laser-scanning-confocal-microscopy-unmasks-proteolytic-activity-of-cell-derived-microparticles
#6
Aurélien Briens, Maxime Gauberti, Jérôme Parcq, Joan Montaner, Denis Vivien, Sara Martinez de Lizarrondo
Cell-derived microparticles (MPs) are nano-sized vesicles released by activated cells in the extracellular milieu. They act as vectors of biological activity by carrying membrane-anchored and cytoplasmic constituents of the parental cells. Although detection and characterization of cell-derived MPs may be of high diagnostic and prognostic values in a number of human diseases, reliable measurement of their size, number and biological activity still remains challenging using currently available methods. In the present study, we developed a protocol to directly image and functionally characterize MPs using high-resolution laser-scanning confocal microscopy...
2016: Theranostics
https://www.readbyqxmd.com/read/26379785/unmasking-silent-endothelial-activation-in-the-cardiovascular-system-using-molecular-magnetic-resonance-imaging
#7
Julie Belliere, Sara Martinez de Lizarrondo, Robin P Choudhury, Aurélien Quenault, Audrey Le Béhot, Christine Delage, Dominique Chauveau, Joost P Schanstra, Jean-Loup Bascands, Denis Vivien, Maxime Gauberti
Endothelial activation is a hallmark of cardiovascular diseases, acting either as a cause or a consequence of organ injury. To date, we lack suitable methods to measure endothelial activation in vivo. In the present study, we developed a magnetic resonance imaging (MRI) method allowing non-invasive endothelial activation mapping in the vasculature of the main organs affected during cardiovascular diseases. In clinically relevant contexts in mice (including systemic inflammation, acute and chronic kidney diseases, diabetes mellitus and normal aging), we provided evidence that this method allows detecting endothelial activation before any clinical manifestation of organ failure in the brain, kidney and heart with an exceptional sensitivity...
2015: Theranostics
https://www.readbyqxmd.com/read/25922513/impact-of-alcohol-consumption-on-the-outcome-of-ischemic-stroke-and-thrombolysis-role-of-the-hepatic-clearance-of-tissue-type-plasminogen-activator
#8
Eloïse Lemarchand, Maxime Gauberti, Sara Martinez de Lizarrondo, Hélène Villain, Yohann Repessé, Axel Montagne, Denis Vivien, Carine Ali, Marina Rubio
BACKGROUND AND PURPOSE: Tissue-type plasminogen activator (tPA) is the only acute treatment for ischemic stroke. Unfortunately, the benefit of tPA-driven thrombolysis is not systematic, and understanding the reasons for this is mandatory. The balance between beneficial and detrimental effects of tPA might explain the limited overall efficiency of thrombolysis. Here, we investigated whether this balance could be influenced by excessive alcohol intake. METHODS: We used a murine model of thromboembolic stroke, coupled to an array of biochemical assays, near-infrared or magnetic resonance imaging scans, 2-photon microscopy, hydrodynamic transfections, and immunohistological techniques...
June 2015: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/25600967/crucial-role-of-the-protein-corona-for-the-specific-targeting-of-nanoparticles
#9
Morteza Mahmoudi, Sara Sheibani, Abbas S Milani, Farhad Rezaee, Maxime Gauberti, Rassoul Dinarvand, Hojatollah Vali
AIMS: We aimed to investigate the physicochemical effects of superparamagnetic iron oxide nanoparticles (SPIONs) on the composition of the protein corona and their correspondence toxicological issues. MATERIALS & METHODS: SPIONs of different sizes and surface charges were exposed to fetal bovine serum. The structure/composition and biological effects of the protein corona-SPION complexes were probed. RESULTS & DISCUSSION: The affinity and level of adsorption of specific proteins is strongly dependent on the size and surface charge of the SPIONs...
January 2015: Nanomedicine
https://www.readbyqxmd.com/read/25505871/molecular-magnetic-resonance-imaging-of-brain-immune-interactions
#10
REVIEW
Maxime Gauberti, Axel Montagne, Aurélien Quenault, Denis Vivien
Although the blood-brain barrier (BBB) was thought to protect the brain from the effects of the immune system, immune cells can nevertheless migrate from the blood to the brain, either as a cause or as a consequence of central nervous system (CNS) diseases, thus contributing to their evolution and outcome. Accordingly, as the interface between the CNS and the peripheral immune system, the BBB is critical during neuroinflammatory processes. In particular, endothelial cells are involved in the brain response to systemic or local inflammatory stimuli by regulating the cellular movement between the circulation and the brain parenchyma...
2014: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/25190438/impaired-glymphatic-perfusion-after-strokes-revealed-by-contrast-enhanced-mri-a-new-target-for-fibrinolysis
#11
Thomas Gaberel, Clement Gakuba, Romain Goulay, Sara Martinez De Lizarrondo, Jean-Luc Hanouz, Evelyne Emery, Emmanuel Touze, Denis Vivien, Maxime Gauberti
BACKGROUND AND PURPOSE: The aim of the present study was to investigate the impact of different stroke subtypes on the glymphatic system using MRI. METHODS: We first improved and characterized an in vivo protocol to measure the perfusion of the glymphatic system using MRI after minimally invasive injection of a gadolinium chelate within the cisterna magna. Then, the integrity of the glymphatic system was evaluated in 4 stroke models in mice including subarachnoid hemorrhage (SAH), intracerebral hemorrhage, carotid ligature, and embolic ischemic stroke...
October 2014: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/24846802/urokinase-versus-alteplase-for-intraventricular-hemorrhage-fibrinolysis
#12
COMPARATIVE STUDY
Thomas Gaberel, Axel Montagne, Flavie Lesept, Maxime Gauberti, Eloïse Lemarchand, Cyrille Orset, Romain Goulay, Thomas Bertrand, Evelyne Emery, Denis Vivien
Intraventricular hemorrhage (IVH) is the most severe form of stroke with intraventricular fibrinolysis (IVF) as a hopeful treatment. Urokinase (uPA) and tissue-type plasminogen activator (tPA) are used for IVF in Human. No clinical trial has evaluated the differential impact of these two fibrinolytics for IVF. Thus, we decided here to compare the use of these two fibrinolytics in a pre-clinical study. IVH was induced in rats by injection of collagenase type VII within the brain parenchyma followed by an IVF...
October 2014: Neuropharmacology
https://www.readbyqxmd.com/read/24576594/tpa-promotes-adamts-4-induced-cspg-degradation-thereby-enhancing-neuroplasticity-following-spinal-cord-injury
#13
Sighild Lemarchant, Mathilde Pruvost, Marie Hébert, Maxime Gauberti, Yannick Hommet, Aurélien Briens, Eric Maubert, Yatma Gueye, François Féron, Didier Petite, Marcel Mersel, Jean-Claude do Rego, Hubert Vaudry, Jari Koistinaho, Carine Ali, Véronique Agin, Evelyne Emery, Denis Vivien
Although tissue plasminogen activator (tPA) is known to promote neuronal remodeling in the CNS, no mechanism of how this plastic function takes place has been reported so far. We provide here in vitro and in vivo demonstrations that this serine protease neutralizes inhibitory chondroitin sulfate proteoglycans (CSPGs) by promoting their degradation via the direct activation of endogenous type 4 disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS-4). Accordingly, in a model of compression-induced spinal cord injury (SCI) in rats, we found that administration of either tPA or its downstream effector ADAMTS-4 restores the tPA-dependent activity lost after the SCI and thereby, reduces content of CSPGs in the spinal cord, a cascade of events leading to an improved axonal regeneration/sprouting and eventually long term functional recovery...
June 2014: Neurobiology of Disease
https://www.readbyqxmd.com/read/24553181/gpib%C3%AE-vwf-blockade-restores-vessel-patency-by-dissolving-platelet-aggregates-formed-under-very-high-shear-rate-in-mice
#14
Audrey Le Behot, Maxime Gauberti, Sara Martinez De Lizarrondo, Axel Montagne, Eloïse Lemarchand, Yohann Repesse, Sylvain Guillou, Cécile V Denis, Eric Maubert, Cyrille Orset, Denis Vivien
Interactions between platelet glycoprotein (Gp) IIb/IIIa and plasma proteins mediate platelet cross-linking in arterial thrombi. However, GpIIb/IIIa inhibitors fail to disperse platelet aggregates after myocardial infarction or ischemic stroke. These results suggest that stability of occlusive thrombi involves additional and as-yet-unidentified mechanisms. In the present study, we investigated the mechanisms driving platelet cross-linking during occlusive thrombus formation. Using computational fluid dynamic simulations and in vivo thrombosis models, we demonstrated that the inner structure of occlusive thrombi is heterogeneous and primarily determined by the rheological conditions that prevailed during thrombus growth...
May 22, 2014: Blood
https://www.readbyqxmd.com/read/24354644/lack-of-secondary-microthrombosis-after-thrombin-induced-stroke-in-mice-and-non-human-primates
#15
M Gauberti, S Martinez de Lizarrondo, C Orset, D Vivien
BACKGROUND: Secondary microthrombosis is a major pathophysiologic mechanism leading to brain damage following transient mechanical vascular occlusion (TMVO), the most widely used experimental stroke model. Whether secondary microthrombosis also occurs in non-TMVO stroke models represents an important issue for clinical translation of antimicrothrombosis therapeutic strategies. OBJECTIVES: To assess the occurrence and the pathogenic role of secondary microthrombosis in two thrombin-induced stroke models in mice and non-human primates (Macaca mulatta)...
2014: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/24105700/intracerebral-hematomas-disappear-on-t2-weighted-images-during-normobaric-oxygen-therapy
#16
Thomas Gaberel, Clement Gakuba, Marie Hebert, Axel Montagne, Veronique Agin, Marina Rubio, Evelyne Emery, Denis Vivien, Maxime Gauberti
BACKGROUND AND PURPOSE: The aim of the present study was to investigate the effects of normobaric oxygen (NBO) therapy on T2*-weighted images of intracranial hemorrhages (ICHs). METHODS: Two common models of ICH were performed in mice, and longitudinal T2*-weighted images of the hematomas were acquired under normoxia or NBO. The effects of NBO were also investigated on perfusion-weighted imaging, susceptibility-weighted imaging, and molecular imaging of vascular cell adhesion molecule-1 after ICH...
December 2013: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/23743972/ultra-sensitive-molecular-mri-of-vascular-cell-adhesion-molecule-1-reveals-a-dynamic-inflammatory-penumbra-after-strokes
#17
COMPARATIVE STUDY
Maxime Gauberti, Axel Montagne, Oscar A Marcos-Contreras, Audrey Le Béhot, Eric Maubert, Denis Vivien
BACKGROUND AND PURPOSE: Our aim was to assess the spatiotemporal evolution of the cerebrovascular inflammation occurring after ischemic and hemorrhagic strokes using a recently developed, fast, and ultra-sensitive molecular MRI method. METHODS: We first assessed longitudinally the cerebrovascular inflammation triggered by collagenase-induced hemorrhage and by permanent/transient middle cerebral artery occlusion in mice, using MRI after injection of microparticles of iron oxide targeted to vascular cell adhesion molecule-1 (MPIOs-αVCAM-1)...
July 2013: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/23638158/potential-of-olfactory-ensheathing-cells-from-different-sources-for-spinal-cord-repair
#18
Anne Mayeur, Célia Duclos, Axel Honoré, Maxime Gauberti, Laurent Drouot, Jean-Claude do Rego, Nicolas Bon-Mardion, Laetitia Jean, Eric Vérin, Evelyne Emery, Sighild Lemarchant, Denis Vivien, Olivier Boyer, Jean-Paul Marie, Nicolas Guérout
Spinal cord injury (SCI) induces a permanent disability in patients. To this day no curative treatment can be proposed to restore lost functions. Therefore, extensive experimental studies have been conducted to induce recovery after SCI. One of the most promising therapies is based on the use of olfactory ensheathing cells (OECs). OECs can be obtained from either the olfactory bulbs (OB-OECs) or from olfactory mucosa (OM-OECs), involving a less invasive approach for autotransplantation. However the vast majority of experimental transplantations have been focusing on OB-OECs although the OM represents a more accessible source of OECs...
2013: PloS One
https://www.readbyqxmd.com/read/23219658/immunotherapy-blocking-the-tissue-plasminogen-activator-dependent-activation-of-n-methyl-d-aspartate-glutamate-receptors-improves-hemorrhagic-stroke-outcome
#19
Thomas Gaberel, Richard Macrez, Maxime Gauberti, Axel Montagne, Marie Hebert, Karl-Uwe Petersen, Emmanuel Touze, Véronique Agin, Evelyne Emery, Carine Ali, Denis Vivien
Ischemic and hemorrhagic strokes have different etiologies, but share some pathogenic mechanisms, including a pro-neurotoxic effect of endogenous tissue plasminogen activator (tPA) via N-methyl-d-Aspartate (NMDA) receptors. Thus, in a model of intracerebral hemorrhage in rats, we investigated the therapeutic value of a strategy of immunotherapy (αATD-GluN1 antibody) preventing the interaction of tPA with NMDA receptors. We found that a single intravenous injection of αATD-GluN1 reduced brain edema, neuronal death, microglial activation and functional deficits following intracerebral hemorrhage, without affecting the hematoma volume...
April 2013: Neuropharmacology
https://www.readbyqxmd.com/read/22879098/memantine-improves-safety-of-thrombolysis-for-stroke
#20
Axel Montagne, Marie Hébert, Amandine Jullienne, Flavie Lesept, Audrey Le Béhot, Morgane Louessard, Maxime Gauberti, Cyrille Orset, Carine Ali, Véronique Agin, Eric Maubert, Denis Vivien
BACKGROUND AND PURPOSE: Despite side effects including N-methyl-d-aspartate-mediated neurotoxicity, recombinant tissue-type plasminogen activator (rtPA) remains the only approved acute treatment for ischemic stroke. Memantine, used for treatment of Alzheimer disease, is an antagonist for N-methyl-d-aspartate receptors. We investigated whether memantine could be used as a neuroprotective adjunct therapy for rtPA-induced thrombolysis after stroke. METHODS: In vitro N-methyl-d-aspartate exposure, oxygen and glucose deprivation, and N-methyl-d-aspartate-mediated calcium videomicroscopy experiments were performed on murine cortical neurons in the presence of rtPA and memantine...
October 2012: Stroke; a Journal of Cerebral Circulation
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