Ang Huang, Yun Zhu, Shuhong Liu, Ying Sun, Zherui Liu, Qing-Sheng Liang, Jun Zhao, Bin-Xia Chang, Jing-Feng Bi, Jiang-Tao Liu, Xing-Ran Zhai, Huan Xie, Ning Li, Hui Tian, Lin Han, Yingjie Zhuang, Hongbin Ma, Guang-Ju Teng, Wei Zhang, Guruprasad P Aithal, Dong Ji, Jingmin Zhao, Zhengsheng Zou
BACKGROUND AND AIMS: The use of corticosteroids in chronic drug-induced liver injury (DILI) is an important issue. Our previous randomized controlled trial showed that patients with chronic DILI benefited from a 48-week steroid stepwise reduction (SSR) regimen. However, it remains unclear whether a shorter course of therapy can achieve similar efficacy. In this study, we aimed to assess whether a 36-week SSR can achieve efficacy similar to that of 48-week SSR. METHODS: A randomized open-label trial was performed...
March 14, 2024: Liver International: Official Journal of the International Association for the Study of the Liver