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https://www.readbyqxmd.com/read/29244973/cooperativity-between-antibiotics-and-antiseptics-testing-the-bactericidal-effect
#1
S Jenull, H Laggner, I Hassl, B Velimirov, M Huettinger, N Zemann
OBJECTIVE: Treatment with antibiotics together with local application of antiseptics is common in wound care. We investigated the effectiveness of an antiseptic in two variations: octenidine (Oct) and octenidine+ (Oct+ with isotonic glucose addition). METHOD: Using the agar diffusion test with cultures of pathogenic Staphylococcus aureus and the non-pathogenic Bordetella petrii, we compared the effectiveness of octenidine to the classical antiseptics beta-isodona (povidone-iodine; PI), chlorhexidine (Chl) and taurolin (Tau) alone, and in combination with various common antibiotics to uncover cooperativity between antiseptics and antibiotics...
December 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/29244157/evaluation-of-lambda-cyhalothrin-and-pyriproxyfen-barrier-treatments-for-aedes-albopictus-diptera-culicidae-management-in-urbanized-areas-of-new-jersey
#2
Isik Unlu, Gregory M Williams, Ilia Rochlin, Devi Suman, Yi Wang, Kshitij Chandel, Randy Gaugler
Mosquito control programs in the United States are still searching for best management practices to control the Asian tiger mosquito, Aedes albopictus (Skuse; Diptera: Culicidae). Most intervention methods for this species are either labor intensive (e.g., source reduction) or short-term (e.g., ultra-low-volume adulticiding). We investigated the effectiveness of barrier spray pesticide applications within urban and suburban residential yards in New Jersey as a control strategy using a before-after-control-impact (BACI) approach...
December 13, 2017: Journal of Medical Entomology
https://www.readbyqxmd.com/read/29243896/diagnostics-and-current-care-of-myasthenia-gravis
#3
Sari Atula, Kathrin Pfau, Tapani Salmi, Eero Sihvo, Mikko Haapio, Mika Saarela, Mari Auranen
Myasthenia gravis (MG) is the most common neuromuscular transmission disorder, causing weakness of skeletal muscles on exertion. The course of the disease is highly variable, symptoms and signs may change rapidly due to infection or pregnancy. MG is classified using serological, electrophysiological and pharmaceutical tools. A precise diagnosis allows for the choice of right treatment, predicts the course of disease and hence helps with the follow-up. In this review we present Finnish guidelines for diagnostics, treatment and follow-up of MG patients...
2017: Duodecim; Lääketieteellinen Aikakauskirja
https://www.readbyqxmd.com/read/29243813/antiepileptic-drug-monotherapy-for-epilepsy-a-network-meta-analysis-of-individual-participant-data
#4
REVIEW
Sarah J Nevitt, Maria Sudell, Jennifer Weston, Catrin Tudur Smith, Anthony G Marson
BACKGROUND: Epilepsy is a common neurological condition with a worldwide prevalence of around 1%. Approximately 60% to 70% of people with epilepsy will achieve a longer-term remission from seizures, and most achieve that remission shortly after starting antiepileptic drug treatment. Most people with epilepsy are treated with a single antiepileptic drug (monotherapy) and current guidelines from the National Institute for Health and Care Excellence (NICE) in the United Kingdom for adults and children recommend carbamazepine or lamotrigine as first-line treatment for partial onset seizures and sodium valproate for generalised onset seizures; however a range of other antiepileptic drug (AED) treatments are available, and evidence is needed regarding their comparative effectiveness in order to inform treatment choices...
December 15, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29243368/a-2000-patient-retrospective-assessment-of-a-new-strategy-for-burn-wound-management-in-view-of-infection-prevention-and-treatment
#5
Justyna Glik, Wojciech Łabuś, Diana Kitala, Karolina Mikuś-Zagórska, Christopher D Roberts, Mariusz Nowak, Aleksandra Kasperczyk, Marek Kawecki
Infections in burn patients are still the principal cause of complications in burn injuries. The aim of this study is to assess a new strategy for burn wound management in view of infection prevention and treatment in the experience of the Burn Treatment Center in Siemianowice Śląskie. The applied methodology involved the analysis of patient records describing the hospital's epidemiological situation between 2014 and 2016. The analysis also included the use and cost of antibiotics, silver-containing dressings, and other antiseptics relative to the number of sepsis cases, including those caused by Pseudomonas aeruginosa, as well as the mortality ratio...
December 15, 2017: International Wound Journal
https://www.readbyqxmd.com/read/29243364/perceived-needs-of-carers-of-people-with-psychosis-an-australian-longitudinal-population-based-study-of-caregivers-of-people-with-psychotic-disorders
#6
Abner Weng Cheong Poon, Lynette Joubert, Carol Harvey
Studies have documented the perceived needs of carers of people with psychosis but most recruitment has utilised convenience sampling resulting in limited understanding of carers' needs. This longitudinal study was conducted within the second Australian prevalence study of psychosis, aiming to obtain generalisable findings regarding perceived needs of carers of people with psychosis. Semi-structured interviews were conducted with 98 carers of people with psychosis recruited in the Australian prevalence study of psychosis...
December 15, 2017: Health & Social Care in the Community
https://www.readbyqxmd.com/read/29243188/current-management-of-lipoblastoma
#7
Emmanuelle Séguier-Lipszyc, Artur Baazov, Suzanna Fichman, Shifra Ash, Enrique Freud
Lipoblastoma is a rare and benign tumor arising from embryonal fat cells. It is generally diagnosed in children younger than 3 years of age and can occur in the extremities or on the trunk. We present our series of 10 children with lipoblastoma treated at Schneider Children's Medical Center of Israel between 2011 and 2016. Six boys and four girls underwent tumor resection at a median age of 2 years and 3 months (range 5 months to 5.6 years). Locations were trunk (6), groin (2), perineum (1), and omentum (1)...
December 14, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29242978/animal-models-of-l-dopa-induced-dyskinesia-the-6-ohda-lesioned-rat-and-mouse
#8
REVIEW
Elisabetta Tronci, Veronica Francardo
Appearance of L-DOPA-induced dyskinesia (LID) represents a major limitation in the pharmacological therapy with the dopamine precursor L-DOPA. Indeed, the vast majority of parkinsonian patients develop dyskinesia within 9-10 years of L-DOPA oral administration. This makes the discovery of new therapeutic strategies an important need. In the last decades, several animal models of Parkinson's disease (PD) have been developed, to both study mechanisms underlying PD pathology and treatment-induced side effects (i...
December 14, 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/29242964/-bone-substitute-materials-as-local-drug-carriers-current-status-of-substitutes-of-various-origins
#9
REVIEW
K-D Kühn, C Berberich, H Bösebeck
BACKGROUND: Autologous bone grafts (autografts) are used in surgery for defect filling and impaction grafting during hip socket and femur reconstruction. Because of their superior osteoinductive capacity, autografts are considered the "gold standard" for these treatments. However, because of a better cost-benefit ratio, allografts are also often used. In the case of limited donor availability for autologous or allogenic bone grafts, bone substitute materials (BSMs) are a reasonable alternative or supplement...
December 14, 2017: Der Orthopäde
https://www.readbyqxmd.com/read/29242803/as-a-definitive-choice-of-treatment-joint-and-defect-spanning-multiplanar-tubular-external-fixation-in-the-management-of-pediatric-open-defective-supracondylar-humerus-fracture-a-case-report
#10
Mehmet Demirel, Onur Tunali, Ismail Turkmen, Yavuz Saglam
Introduction: Although supracondylar fractures of the humerus are common in children, open fractures of are extremely rare injuries. Gustilo- Anderson Type-III fractures in the upper extremity are primarily associated with considerable bone loss resulting from high energy trauma. In this study, a case of open pediatric supracondylar humerus fracture treated by a joint and defect spanning multiplanar tubular external fixation is presented. Case Report: A boy aged 3 years suffered from a Gustilo-Anderson Type-IIIA supracondylar humerus fractures...
September 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/29242797/lipoma-arborescens-eyes-see-what-mind-knows
#11
Himanshu Gurunath Kulkarni, Gurunath S Kulkarni, Prakash G Kulkarni
Introduction: Lipoma arborescens is a rare lesion, benign in nature and was first described in detail in 1957. <200 cases have been reported in the literature by now. It consists of subsynovial villous proliferation of mature fat cells. Since the incidence of the condition is very rare, definite etiology has not established. Arthroscopic or open synovectomy has been the treatment of choice of the lesion. Case Report: We present you a case of lipomatosis arborescens of the right knee in a 28-year-old male...
September 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/29242788/obturator-dislocation-of-hip-with-ipsilateral-fracture-neck-femur-a-case-report
#12
Sumit Kumar Jain, Parit Aggarwal, Arun Yadav
Introduction: Traumatic dislocation of the hip with ipsilateral fracture neck femur is a rare injury because of the different mechanism of both these injuries. The management of such injuries is a challenge as the chances of nonunion and avascular necrosis of femoral head are very high with fixation methods. We report a case of obturator dislocation of the hip with ipsilateral fracture neck of the femur which was treated with uncemented total hip replacement. Case Report: A 32-year-old male sustained obturator dislocation with ipsilateral fracture neck femur following road traffic accident...
September 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/29242560/characterising-the-nicotine-metabolite-ratio-and-its-association-with-treatment-choice-a-cross-sectional-analysis-of-stop-smoking-services-in-england
#13
Lion Shahab, Emily Mortimer, Linda Bauld, Jennifer A McGowan, Ann McNeill, Rachel F Tyndale
Pharmacotherapy provision based on Nicotine Metabolite Ratio (NMR) status (slow/normal metabolism) may improve smoking cessation rates. However, it is unclear whether NMR status is consistent across patient characteristics and current treatment choice. Data come from 1,826 participants attending Stop Smoking Services (SSS) across England in 2012/13. Sociodemographic, mental/physical health, smoking and treatment characteristics (nicotine replacement therapy vs. other pharmacotherapy; group vs. one-to-one behavioural support) were assessed...
December 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29242403/does-pet-reconstruction-method-affect-deauville-scoring-in-lymphoma-patients
#14
Blandine Enilorac, Charline Lasnon, Cathy Nganoa, Christophe Fruchart, Anne Claire Gac, Gandhi Damaj, Nicolas Aide
Background: When scoring 18F-Fluorodeoxyglucose (FDG) positron emission tomography (PET) with the Deauville scale (DS), the quantification of tumor and reference organs limits the problem of optical misinterpretation. Compared to conventional reconstruction algorithms, point spread function (PSF) modeling significantly increases standardized uptake values (SUVs) in tumors but only moderately in the liver, which could affect the DS. We investigated whether the choice of the reconstruction algorithm affects the DS and whether discordances affect the capability of FDG PET to stratify lymphoma patients...
December 14, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29242040/valuing-the-delivery-of-dental-care-heterogeneity-in-patients-preferences-and-willingness-to-pay-for-dental-care-attributes
#15
Ivan Sever, Miroslav Verbič, Eva Klaric Sever
OBJECTIVES: To examine the amount of heterogeneity in patients' preferences for dental care, what factors affect their preferences, and how much they would be willing to pay for improvement in specific dental care attributes. METHODS: A discrete choice experiment (DCE) was used to elicit patients' preferences. Three alternative dental care services that differed in the type of care provider, treatment explanation, dental staff behavior, waiting time and treatment cost were described to patients...
December 11, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/29241936/teriparatide-and-denosumab-treatment-for-pregnancy-and-lactation-associated-osteoporosis-with-multiple-vertebral-fractures-a-case-study
#16
Akifumi Ijuin, Hiromi Yoshikata, Ryoko Asano, Taku Tsuburai, Ritsuko Kikuchi, Hideya Sakakibara
OBJECTIVE: Pregnancy and lactation-associated osteoporosis (PLO) is a rare disease, which can lead to vertebral fractures in women of reproductive age. No treatment strategy for PLO has been established. Here we report a case of PLO treated with teriparatide followed by denosumab, in which remarkable improvement in bone mineral density (BMD) was achieved. CASE REPORT: A 27-year-old woman experienced severe back pain two weeks after her first delivery. PLO was diagnosed from her low BMD and multiple vertebral compression fractures...
December 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29241929/fertility-outcomes-following-pelvic-embolization-in-women-with-acquired-uterine-arteriovenous-malformation
#17
Cheng-Yu Ho, Kok-Min Seow, Lee-Wen Huang, Yieh-Loong Tsai
OBJECTIVE: Acquired uterine arteriovenous malformation (UAVM) is a rare, life-threatening disease. Angiography with uterine arterial embolization (UAE) is the diagnostic tool and a choice of fertility-sparing treatment. Here, we present a series of five successful pregnancies after embolization of UAVM. CASE REPORTS: Three reproductive aged women were treated for UAVM, resulting in five successful pregnancies. Their past history suggested that three cases had had previous uterine procedures, including second trimester abortion and elective dilatation and curettage...
December 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29241898/patient-preferences-for-device-aided-treatments-indicated-for-advanced-parkinson-disease
#18
Thomas Marshall, Amy Pugh, Angelyn Fairchild, Steven Hass
BACKGROUND: Effective treatment for advanced Parkinson disease (PD) uncontrolled with oral medication includes device-aided therapies such as deep brain stimulation (DBS) and continuous levodopa-carbidopa infusion to the duodenum via a portable pump. OBJECTIVE: Our objective was to quantify patient preferences for attributes of these device-aided treatments. METHODS: We administered a Web-enabled survey to 401 patients in the United States...
December 2017: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/29241877/adult-onset-still-s-disease
#19
REVIEW
Javier Narváez
Adult onset Still's disease is a rare systemic condition at the crossroads between auto-inflammatory syndromes and autoimmune diseases, with considerable heterogeneity in terms of clinical presentation, evolution and severity. This article reviews the main advances and lesser known aspects of this entity related to its clinical spectrum (atypical cutaneous lesions, unusual manifestations, macrophage activation syndrome, disease phenotypes), the emerging controversy around its association with delayed malignancy, the search for new biomarkers for its diagnosis, evaluation of prognosis (clinical factors, prognostic indexes and biomarkers to identify patients at risk of severe organ failure or life-threatening complications), and the determinants in the choice of biological treatment...
December 11, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/29241715/engaging-patients-in-decisions-about-cancer-screening-exploring-the-decision-journey-through-the-use-of-a-patient-portal
#20
Steven H Woolf, Alex H Krist, Jennifer Elston Lafata, Resa M Jones, Rebecca R Lehman, Camille J Hochheimer, Roy T Sabo, Dominick L Frosch, Brian J Zikmund-Fisher, Daniel R Longo
INTRODUCTION: Engaging patients to make informed choices is paramount but difficult in busy practices. This study sought to engage patients outside the clinical setting to better understand how they approach cancer screening decisions, including their primary concerns and their preferences for finalizing their decision. METHODS: Twelve primary care practices offering patients an online personal health record invited eligible patients to complete a 17-item online interactive module...
December 11, 2017: American Journal of Preventive Medicine
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