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https://www.readbyqxmd.com/read/29346453/yearly-fluctuations-of-flower-landscape-in-a-mediterranean-scrubland-consequences-for-floral-resource-availability
#1
Víctor Flo, Jordi Bosch, Xavier Arnan, Clara Primante, Ana M Martín González, Helena Barril-Graells, Anselm Rodrigo
Species flower production and flowering phenology vary from year to year due to extrinsic factors. Inter-annual variability in flowering patterns may have important consequences for attractiveness to pollinators, and ultimately, plant reproductive output. To understand the consequences of flowering pattern variability, a community approach is necessary because pollinator flower choice is highly dependent on flower context. Our objectives were: 1) To quantify yearly variability in flower density and phenology; 2) To evaluate whether changes in flowering patterns result in significant changes in pollen/nectar composition...
2018: PloS One
https://www.readbyqxmd.com/read/29346018/the-tortoise-and-the-hare-interactions-between-reinforcement-learning-and-working-memory
#2
Anne G E Collins
Learning to make rewarding choices in response to stimuli depends on a slow but steady process, reinforcement learning, and a fast and flexible, but capacity-limited process, working memory. Using both systems in parallel, with their contributions weighted based on performance, should allow us to leverage the best of each system: rapid early learning, supplemented by long-term robust acquisition. However, this assumes that using one process does not interfere with the other. We use computational modeling to investigate the interactions between the two processes in a behavioral experiment and show that working memory interferes with reinforcement learning...
January 18, 2018: Journal of Cognitive Neuroscience
https://www.readbyqxmd.com/read/29345593/antithrombotic-therapy-after-tavr
#3
Tobias Geisler, Michal Droppa, Karin Mueller, Oliver Borst
Transvascular aortic valve replacement (TAVR) has emerged as a treatment option in patients with severe aortic stenosis who are inoperable and has recently been evaluated in patients with intermediate surgical risk. The number of procedures is increasing worldwide in parallel with the demographic changes in industrial countries. The risk for cerebral embolism is of main concern and represents a major determinant for prognosis and quality of live after TAVR. The empiric antithrombotic therapy consists of dual antiplatelet therapy (DAPT); however the risk-benefit of this approach is lacking evidence from randomized, placebo-controlled trials regarding choice and duration of antithrombotic treatment...
January 17, 2018: Current Vascular Pharmacology
https://www.readbyqxmd.com/read/29345003/investigation-of-attributes-which-guide-choice-in-cataract-surgery-services-in-urban-sydney-australia
#4
Celeste Gilbert, Lisa Keay, Anna Palagyi, Vu Quang Do, Peter McCluskey, Andrew White, Nicole Carnt, Fiona Stapleton, Tracey-Lea Laba
BACKGROUND: It is critical to consult patients to develop patient-centred cataract surgery care. We aimed to identify attributes patients consider when making decisions about cataract surgery in an Australian context, where both publicly and privately funded surgery are available. This is the first step in investigating how decisions are made about cataract surgery services. METHODS: This observational qualitative study was undertaken in two public hospitals and one private practice in Sydney, Australia...
January 17, 2018: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/29344940/obstetric-and-neonatal-outcomes-for-women-intending-to-use-immersion-in-water-for-labour-and-birth-in-western-australia-2015-2016-a-retrospective-audit-of-clinical-outcomes
#5
Lucy Lewis, Yvonne L Hauck, Janice Butt, Janet Hornbuckle
BACKGROUND: Research supports water immersion for labour if women are healthy, with no obstetric or medical risk factors. AIMS: To evaluate the obstetric and neonatal outcomes of women intending to use immersion in water for labour or birth. METHODS: Retrospective audit of clinical outcomes for women intending to labour or birth in water conducted between July 2015 and June 2016, at a tertiary maternity hospital in Western Australia. Obstetric and neonatal data were collected from medical records...
January 17, 2018: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29344884/analyzing-dna-methylation-patterns-during-tumor-evolution
#6
Heng Pan, Olivier Elemento
Epigenetic modifications play a key role in cellular development and tumorigenesis. Recent large-scale genomic studies have shown that mutations in players of the epigenetic machinery and concomitant perturbation of epigenomic patterning are frequent events in tumors. Among epigenetic marks, DNA methylation is one of the best studied. Hyper- and hypo-methylation events of specific regulatory elements (such as promoters and enhancers) are sometimes thought to be correlated with expression of nearby genes. High-throughput bisulfite converted sequencing is currently the technology of choice for studying DNA methylation in base-pair resolution and on whole-genome scale...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29344846/evaluation-of-psychosocial-and-biological-parameters-in-women-seeking-for-a-caesarean-section-and-women-who-are-aiming-for-vaginal-delivery-a-cross-sectional-study
#7
Benjamin Tuschy, Sebastian Berlit, Paul Stützer, Stefanie Lis, Christian Schmahl, Ulf Baumgärtner, Marc Sütterlin
PURPOSE: To investigate psychosocial and biological parameters that may influence decision-making concerning the mode of delivery in women with caesarean section on maternal request (CSMR). METHODS: Two hundred and two women were enrolled prospectively. The study sample (n = 93) consisted of women who aimed for CSMR, the control sample were women who seeked for vaginal delivery (n = 109). Parturients of both samples were enrolled during the pre-birth counselling at the delivery room at the University Medical Centre Mannheim, University Heidelberg, Germany...
January 17, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29344528/psychometric-characteristics-of-clinical-reasoning-problems-crps-and-its-correlation-with-routine-multiple-choice-question-mcq-in-cardiology-department
#8
Zahra Derakhshandeh, Mitra Amini, Javad Kojuri, Marziyeh Dehbozorgian
Introduction: Clinical reasoning is one of the most important skills in the process of training a medical student to become an efficient physician. Assessment of the reasoning skills in a medical school program is important to direct students' learning. One of the tests for measuring the clinical reasoning ability is Clinical Reasoning Problems (CRPs). The major aim of this study is to measure psychometric qualities of CRPs and define correlation between this test and routine MCQ in cardiology department of Shiraz medical school...
January 2018: Journal of Advances in Medical Education & Professionalism
https://www.readbyqxmd.com/read/29344456/early-clinical-exposure-as-a-learning-tool-to-teach-neuroanatomy-for-first-year-mbbs-students
#9
Maitreyee Kar, Chinmaya Kar, Hironmoy Roy, Parmod Goyal
Context: Early clinical exposure (ECE) is one of the important tools to teach basic science to the MBBS students. It is one form of vertical integration between basic science and clinical subjects. This study is an effort at exploring the use of ECE as a motivational tool toward better learning in neuroanatomy for first year MBBS students. Aim: This study aims to make the students interested and motivated to study neuroanatomy by using ECE as learning tool in neuroanatomy and to make the students enable to retain the knowledge of neuroanatomy more efficiently and correlate the knowledge of neuroanatomy with neuromedicine...
December 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/29343746/the-static-magnetic-field-remotely-boosts-the-efficiency-of-doxorubicin-through-modulating-ros-behaviors
#10
Behnam Hajipour Verdom, Parviz Abdolmaleki, Mehrdad Behmanesh
Exposure to magnetic field (MF) can affect cellular metabolism remotely. Cardio-toxic effects of Doxorubicin (DOXO) have limited clinical uses at high dose. MF due to its effect on reactive oxygen species (ROS) lifetime, may provide a suitable choice to boost the efficacy of this drug at low dose. Here, we investigated the potential effects of homogenous static magnetic field (SMF) on DOXO-induced toxicity and proliferation rate of cancer cells. The results indicated that SMF similar to DOXO decreased the cell viability as well as the proliferation rate of MCF-7 and HFF cells...
January 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29342360/sustained-delivery-of-doxorubicin-via-acetalated-dextran-scaffold-prevents-glioblastoma-recurrence-after-surgical-resection
#11
Elizabeth G Graham-Gurysh, Kathryn M Moore, Andrew B Satterlee, Kevin T Sheets, Feng-Chang Lin, Eric M Bachelder, C Ryan Miller, Shawn Hingtgen, Kristy M Ainslie
The primary cause of mortality for glioblastoma (GBM) is local tumor recurrence following standard-of-care therapies, including surgical resection. With most tumors recurring near the site of surgical resection, local delivery of chemotherapy at the time of surgery is a promising strategy. Herein drug loaded polymer scaffolds with two distinct degradation profiles were fabricated to investigate the effect of local drug delivery rate on GBM recurrence following surgical resection. The novel biopolymer, acetalated dextran (Ace-DEX), was compared to commercially available polyester, poly(L-lactide) (PLA)...
January 17, 2018: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/29342192/white-matter-tract-specific-quantitative-analysis-in-multiple-sclerosis-comparison-of-optic-radiation-reconstruction-techniques
#12
Chenyu Wang, Alexander Klistorner, Linda Ly, Michael H Barnett
The posterior visual pathway is commonly affected by multiple sclerosis (MS) pathology that results in measurable clinical and electrophysiological impairment. Due to its highly structured retinotopic mapping, the visual pathway represents an ideal substrate for investigating patho-mechanisms in MS. Therefore, a reliable and robust imaging segmentation method for in-vivo delineation of the optic radiations (OR) is needed. However, diffusion-based tractography approaches, which are typically used for OR segmentation are confounded by the presence of focal white matter lesions...
2018: PloS One
https://www.readbyqxmd.com/read/29341498/review-article-sepsis-in-the-emergency-department-part-2-investigations-and-monitoring
#13
REVIEW
Amith Shetty, Stephen Pj Macdonald, Gerben Keijzers, Julian M Williams, Benjamin Tang, Bas de Groot, Kelly Thompson, John F Fraser, Simon Finfer, Rinaldo Bellomo, Jonathan Iredell
Sepsis is characterised by organ dysfunction resulting from infection, with no reliable single objective test and current diagnosis based on clinical features and results of investigations. In the ED, investigations may be conducted to diagnose infection as the cause of the presenting illness, identify the source, distinguish sepsis from uncomplicated infection (i.e. without organ dysfunction) and/ or risk stratification. Appropriate sample collection for microbiological testing remains key for subsequent confirmation of diagnosis and rationalisation of antimicrobials...
January 16, 2018: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/29340869/intervention-effect-of-repetitive-tms-on-behavioral-adjustment-after-error-commission-in-long-term-methamphetamine-addicts-evidence-from-a-two-choice-oddball-task
#14
Qiongdan Liang, Jia Lin, Jiemin Yang, Xiang Li, Yijiang Chen, Xianxin Meng, Jiajin Yuan
Behavioral adjustment plays an important role in the treatment and relapse of drug addiction. Nonetheless, few studies have examined behavioral adjustment and its plasticity following error commission in methamphetamine (METH) dependence, which is detrimental to human health. Thus, we investigated the behavioral adjustment performance following error commission in long-term METH addicts and how it varied with the application of repetitive transcranial magnetic stimulation (rTMS) of the left dorsolateral prefrontal cortex (DLPFC)...
January 16, 2018: Neuroscience Bulletin
https://www.readbyqxmd.com/read/29340722/new-frontiers-and-cutting-edge-applications-in-ultra-high-performance-liquid-chromatography-through-latest-generation-superficially-porous-particles-with-particular-emphasis-to-the-field-of-chiral-separations
#15
Martina Catani, Simona Felletti, Omar H Ismail, Francesco Gasparrini, Luisa Pasti, Nicola Marchetti, Chiara De Luca, Valentina Costa, Alberto Cavazzini
About ten years after their introduction to the market (happened in 2006), the so-called second generation superficially porous particles (SPPs) have undoubtedly become the benchmark as well as, very often, the preferred choice for many applications in liquid chromatography (LC), when high efficiency and fast separations are required. This trend has interested practically all kinds of separations, with the only exception of chiral chromatography (at least so far). The technology of production of base SPPs is advanced, relatively simple and widely available...
January 16, 2018: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29339986/seeking-optimal-nutrition-for-healthy-body-mass-reduction-among-former-athletes
#16
Dominika Maciejewska, Małgorzata Michalczyk, Maja Czerwińska-Rogowska, Marcin Banaszczak, Karina Ryterska, Karolina Jakubczyk, Jakub Piotrwski, Joanna Hołowko, Arleta Drozd, Paweł Wysokińki, Krzysztof Ficek, Krzysztof Wilk, Anna Lubkowska, Paweł Cięszczyk, Jerzy Bertrand, Ewa Stachowska
The aim of the study was to investigate the efficacy of 6 week Mediterranean diet or 30% calorie restriction on the fatty acid profile and eicosanoids (hydroxyoctadecadienoi acids and hydroxyeicosatetraenoic acids) concentration. Furthermore, basic biochemical variables such as insulin, glucose, HOMA-IR, and a lipid profile were estimated. The study enrolled 94 Caucasian former athletes aged 20-42, with body height of 179 ± 16.00 cm and body mass of 89.26 ± 13.25 kg who had not been active for at least 5 years...
December 2017: Journal of Human Kinetics
https://www.readbyqxmd.com/read/29338537/antidepressant-prescriptions-and-mental-health-nurses-an-observational-study-in-dutch-general-practice-from-2011-to-2015
#17
Tessa Magnée, Derek P de Beurs, Francois G Schellevis, Peter F Verhaak
PURPOSE: The purpose of this study was to investigate developments in antidepressant prescriptions by Dutch general practitioners, alongside the national introduction of mental health nurses. Antidepressant prescriptions are very common in general practice, but are often not in line with recommendations. The recent introduction of mental health nurses may have decreased antidepressant prescriptions, as general practitioners (GPs) have greater potential to offer psychological treatment as a first choice option instead of medication...
January 17, 2018: Scandinavian Journal of Primary Health Care
https://www.readbyqxmd.com/read/29338170/peald-of-sio2-and-al2o3-thin-films-on-polypropylene-investigations-of-the-film-growth-at-the-interface-stress-and-gas-barrier-properties-of-dyads
#18
Maximilian Gebhard, Lukas Mai, Lars Banko, Felix Mitschker, Christian Hoppe, Montgomery Jaritz, Dennis Kirchheim, Christoph Zekorn, Teresa de Los Arcos, Dario Grochla, Rainer Dahlmann, Guido Grundmeier, Peter Awakowicz, Alfred Ludwig, Anjana Devi
A study on the plasma-enhanced atomic layer deposition (PEALD) of amorphous inorganic oxides, SiO2 and Al2O3, on polypropylene (PP) was carried out with respect to growth taking place at the interface of the polymer substrate and the thin film employing in-situ quartz-crystal microbalance (QCM) experiments. A model-layer of spin-coated PP (scPP) was deposited on QCM crystals prior to depositions to allow a transfer of findings from QCM studies to industrially applied PP foil. The influence from precursor choice (trimethyl-aluminum (TMA) vs...
January 17, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29338119/management-of-morning-hypertension-a-consensus-statement-of-an-asian-expert-panel
#19
REVIEW
Ji-Guang Wang, Kazuomi Kario, Chen-Huan Chen, Jeong-Bae Park, Satoshi Hoshide, Yong Huo, Hae-Young Lee, Yan Li, Masaki Mogi, Masanori Munakata, Sungha Park, Dingliang Zhu
Morning blood pressure (BP) surge is an important aspect of hypertension research. Morning BP monitoring could be a clinically relevant concept in the therapeutic management of hypertension and in the prevention of cardiovascular complications by defining and treating morning hypertension. Because antihypertensive medication is often taken in the morning, uncontrolled morning BP during the trough effect hours could be a hallmark of inadequate choice of antihypertensive regimen, such as the use of short- or intermediate-acting drugs, underdosing of drugs, or no use or underuse of combination therapy...
January 16, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29337290/threefold-growth-efficiency-improvement-of-silica-nanosprings-by-using-silica-nanosprings-as-a-substrate
#20
Giancarlo Corti, Justin L Brown, Negar Rajabi, Dave N McIlroy
The growth efficiency of one dimension(1D) nanostructures via the vapor-liquid-solid process is commonly attributed to parameters such as precursor vapor pressure, substrate temperature, and the choice of the catalyst. The work presented herein is an investigation of the use of silica nanosprings (SN) as a 3D substrate for improving the growth efficiency of SN themselves. Silica nanosprings are a 1D nanomaterial that form a nonwoven structure with optimal geometric characteristics and surface properties that mitigate collisions between growing nanosprings and ripening of the gold catalyst, which should improve SN yield...
January 16, 2018: Nanotechnology
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