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https://www.readbyqxmd.com/read/28935209/establishment-and-analysis-of-false-vocal-folds-hypertrophy-model-in-excised-canine-larynges
#1
Yanchao Jiao, Ruiqing Wang, Qingkai Zeng, Xinlin Xu, Yu Zhang, Bobby Leggon, Jack Jiang, Peiyun Zhuang
OBJECTIVE: This study aimed to investigate the role of false vocal folds (FVFs) medialization in phonation and the acoustic impact of ventricular hypertrophy by establishing an FVF hypertrophy model. STUDY DESIGN: A prospective in vitro experiment was carried out. SETTING: The study was carried out using a pseudolung platform with high-speed camera in a soundproof room. MATERIALS AND METHODS: Control, degree I, and degree II FVFs hypertrophy were simulated in 10 excised larynges via fructose injection of 0...
September 18, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28910442/unilateral-laryngoscopic-findings-associated-with-response-to-gabapentin-in-patients-with-chronic-cough
#2
John Paul Giliberto, Daniel Dibildox, Albert Merati
Importance: Chronic cough is a debilitating, often multifactorial problem. Vagal neuropathy has been proposed as a cause for a fraction of these cases. There are certain features that support the clinical diagnosis of vagal neuropathy. It is hypothesized that patients with neurogenic cough who have vocal fold motion asymmetry (VFMA) on laryngoscopy will be more likely to respond to gabapentin. Objective: To evaluate the association between the history, physical and videostroboscopic examinations, and clinical response to gabapentin...
September 14, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28900151/in-situ-vocal-fold-properties-and-pitch-prediction-by-dynamic-actuation-of-the-songbird-syrinx
#3
Daniel N Düring, Benjamin J Knörlein, Coen P H Elemans
The biomechanics of sound production forms an integral part of the neuromechanical control loop of avian vocal motor control. However, we critically lack quantification of basic biomechanical parameters describing the vocal organ, the syrinx, such as material properties of syringeal elements, forces and torques exerted on, and motion of the syringeal skeleton during song. Here, we present a novel marker-based 3D stereoscopic imaging technique to reconstruct 3D motion of servo-controlled actuation of syringeal muscle insertions sites in vitro and focus on two muscles controlling sound pitch...
September 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28895162/laryngeal-emg-preferential-damage-of-the-posterior-cricoarytenoid-muscle-branches-especially-in-iatrogenic-recurrent-laryngeal-nerve-lesions
#4
Gerhard Foerster, Andreas H Mueller
OBJECTIVE: Laryngeal electromyography (LEMG) of the thyroarytenoid (TA) muscle alone may not be sufficient in all patients to characterize or prove a recurrent laryngeal nerve (RLN) lesion in cases of vocal fold immobility. LEMG of the posterior cricoarytenoid (PCA) muscle may provide additional information. STUDY DESIGN: Retrospective review. METHOD: Between 2008 and 2016, 339 patients in our laryngeal paralysis clinic were examined by transcutaneous needle TA-LEMG and, if tolerated, by PCA-LEMG...
September 12, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28894838/recurrent-respiratory-papillomatosis-rrp-time-for-a-reckoning
#5
Peter Kin Cho Goon, Lars-Uwe Scholtz, Holger Sudhoff
OBJECTIVES: Recurrent respiratory papillomatosis (RRP) is a rare disease, but one with severe morbidity and occasional mortality. The aetiological agent is human papillomavirus (HPV), and HPV types 6 and 11 account for over 90% of all cases. In the active phase of the disease, patients require multiple hospital admissions for surgical removal or ablation of these benign tumors, which are likely to obstruct the airways if left unchecked. Long-term sequelae include scarring of the vocal cords, change in voice timbre, or even muteness if a tracheostomy is required...
August 2017: Laryngoscope Investigative Otolaryngology
https://www.readbyqxmd.com/read/28894815/development-of-a-voice-disorder-work-productivity-inventory-utilizing-cognitive-interviewing-technique
#6
John Paul Giliberto, Qiubei Zhu, Tanya K Meyer
OBJECTIVES/HYPOTHESIS: Voice disorders have been shown to impair workplace productivity primarily by reduced efficiency while at work (presenteeism) versus increased days missed (absenteeism). Work productivity measures such as the Work Productivity and Activity Impairment (WPAI) Questionnaire or the World Health Organization Health - Work Performance Questionnaire (HPQ) can be customized to a specific disease but do not fully capture impaired work productivity associated with voice disorders...
December 2016: Laryngoscope Investigative Otolaryngology
https://www.readbyqxmd.com/read/28891238/excised-larynx-evaluation-of-subthyroid-cartilage-approach-to-medialization-thyroplasty
#7
James D Thompson, Matthew R Hoffman, Austin Scholp, Erin E Devine, Jack J Jiang, Timothy M McCulloch
OBJECTIVES/HYPOTHESIS: To describe an alternative approach to medialization thyroplasty involving dissection underneath the thyroid cartilage with placement of a Gore-Tex implant, and to evaluate its effect on a range of phonatory measures using an excised canine larynx model. STUDY DESIGN: Animal model. METHODS: On each of eight excised canine larynges, the conditions of normal, paralysis, medialization thyroplasty by standard transthyroid cartilage approach, and medialization thyroplasty by experimental subthyroid cartilage approach were performed...
September 11, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28887674/robot-assisted-transaxillary-thyroidectomy-ratt-a-series-appraisal-of-more-than-250-cases-from-europe
#8
Gabriele Materazzi, Lorenzo Fregoli, Piermarco Papini, Sohail Bakkar, Malince Chicas Vasquez, Paolo Miccoli
BACKGROUND: Robot-assisted transaxillary thyroidectomy (RATT) is widely accepted in Asian countries. However, concerns regarding the balance between its real advantages and safety and cost have been raised by North American authorities. In Europe, assessments have been limited by small numbers since now. The purpose here is to report a large European experience with RATT. METHODS: A retrospective analysis was conducted of 257 patients who underwent RATT for nodular disease between February 2012 and September 2016...
September 8, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28882539/multidimensional-effects-of-voice-therapy-in-patients-affected-by-unilateral-vocal-fold-paralysis-due-to-cancer
#9
Camila Barbosa Barcelos, Paula Angélica Lorenzon Silveira, Renata Lígia Vieira Guedes, Aline Nogueira Gonçalves, Luciana Dall'Agnol Siqueira Slobodticov, Elisabete Carrara-de Angelis
INTRODUCTION: Patients with unilateral vocal fold paralysis may demonstrate different degrees of voice perturbation depending on the position of the paralyzed vocal fold. Understanding the effectiveness of voice therapy in this population may be an important coefficient to define the therapeutic approach. OBJECTIVE: To evaluate the voice therapy effectiveness in the short, medium and long-term in patients with unilateral vocal fold paralysis and determine the risk factors for voice rehabilitation failure...
August 24, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28874852/acoustic-allometry-revisited-morphological-determinants-of-fundamental-frequency-in-primate-vocal-production
#10
Maxime Garcia, Christian T Herbst, Daniel L Bowling, Jacob C Dunn, W Tecumseh Fitch
A fundamental issue in the evolution of communication is the degree to which signals convey accurate ("honest") information about the signaler. In bioacoustics, the assumption that fundamental frequency (f o) should correlate with the body size of the caller is widespread, but this belief has been challenged by various studies, possibly because larynx size and body size can vary independently. In the present comparative study, we conducted excised larynx experiments to investigate this hypothesis rigorously and explore the determinants of f o...
September 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28872158/stabilometric-findings-in-patients-affected-by-organic-dysphonia-before-and-after-phonomicrosurgery
#11
A Nacci, S O Romeo, S Berrettini, J Matteucci, M D Cavaliere, V Mancini, E Panicucci, F Ursino, B Fattori
The purpose of this study is to understand if there is any alteration in the posture of patients affected by organic dysphonia and describe possible postural modifications after phonomicrosurgery on the vocal folds. Forty subjects (22 males, 18 females; mean age 32.6 ± 7.5 years) suffering from organic dysphonia (15 cases of polyps, 11 submucosal retention cysts, 10 bilateral fibrous vocal fold nodules and 4 bilateral Reinke's oedema) were examined by open-eye and closed-eye posturography while breathing spontaneously before surgery, 24 hours after surgery and after 6 months...
August 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28871957/-expression-of-brca2-in-tumor-tissues-in-patients-with-laryngeal-squamous-cell-carcinoma-and-its-clinical-significance
#12
Xingbo He, Chuan Liu, Zhihai Wang, Zhitao Gong, Guohua Hu
Objective To determine the role of breast cancer susceptibility gene 2 (BRCA2) in laryngeal squamous cell carcinoma and investigate its clinical implication. Methods The expression of BRCA2 was examined by immunohistochemistry in 62 tissues of pathologically identified laryngeal squamous cell carcinoma and 23 tissues of vocal fold polyp. The relationships between BRCA2 expression and clinicopathological characteristics were further analyzed. The expression of BRCA2 mRNA and protein were detected by real-time quantitative PCR (qRT-PCR) and Western blot analysis in pathologically identified laryngeal squamous cell carcinoma tissues and corresponding normal tissues...
August 2017: Xi Bao Yu Fen Zi Mian Yi Xue za Zhi, Chinese Journal of Cellular and Molecular Immunology
https://www.readbyqxmd.com/read/28871836/vocal-fold-immobility-due-to-birth-trauma-a-systematic-review-and-pooled-analysis
#13
Jad Jabbour, Lauren M North, David Bougie, Thomas Robey
Objectives To describe the present understanding of birth trauma-related vocal fold immobility and quantitatively compare it with idiopathic congenital vocal fold immobility to explore whether it is a discrete entity. Data Sources PubMed, Ovid, and Cochrane databases. Review Methods English-language, observational, or experimental studies involving infants with idiopathic congenital or birth trauma-related vocal fold immobility were included. Data from these studies were pooled with our institution's vocal fold immobility database, with the resultant idiopathic congenital and birth trauma cohorts compared regarding patterns and outcomes of immobility...
September 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28869050/long-term-voice-outcome-after-thyroidectomy-using-energy-based-devices
#14
Min Woo Park, Seung-Kuk Baek, Euy-Hyun Park, Kwang-Yoon Jung
OBJECTIVE: Voice dysfunction is frequently reported after thyroidectomy even in absence of vocal fold paralysis. The energy-based devices such as Harmonic scalpel (HS) or LigaSure (LS) are commonly used in conventional thyroidectomy. The objective of this study was to investigate the long-term voice outcome after total thyroidectomy using energy based devices. METHODS: Patients who underwent total thyroidectomy with or without central neck dissection for papillary thyroid carcinoma using HS or LS from April 2012 to March 2013 were involved...
August 28, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28867161/hyaluronidase-injection-in-the-vocal-folds-for-vocal-hemorrhage-reinke-edema-and-hyaluronic-acid-overinjection-a-novel-application-in-the-larynx
#15
Peak Woo
Hyaluronidase (HAase) injection into the vocal folds is an off-label use of an enzyme for liquefaction of hyaluronic acid (HA). HAase injection was performed in 14 cases in 13 patients. Office and operative injections of HAase were performed. The indications were five cases of overinjection of HA, six cases of Reinke edema and polypoid corditis, and three cases of acute vocal hemorrhage with early fusiform polyp formation. All the patients tolerated the HAase without complications. Significant voice improvements were noted between pre- and postinjection procedures as evaluated by a self-rating of voice by the Voice Handicap Index-10...
August 31, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28866750/relationship-between-laryngeal-sensory-deficits-aspiration-and-pneumonia-in-patients-with-dysphagia
#16
Asako Kaneoka, Jessica M Pisegna, Haruhi Inokuchi, Rumi Ueha, Takao Goto, Takaharu Nito, Cara E Stepp, Michael P LaValley, Nobuhiko Haga, Susan E Langmore
The laryngeal adductor reflex (LAR) is an airway protective reflex that manifests as a brief vocal fold closure in response to laryngeal stimulation. This study examined if the absence of the LAR in response to touch delivered by a laryngoscope is associated with penetration/aspiration or pneumonia in patients with dysphagia. Inpatients at a teaching hospital with clinical symptoms of dysphagia were recruited upon referral to the otolaryngology clinic for a swallowing evaluation. Otolaryngologists observed the status of secretions and touched each arytenoid with the tip of the laryngoscope...
September 2, 2017: Dysphagia
https://www.readbyqxmd.com/read/28863607/effect-of-level-difference-between-left-and-right-vocal-folds-on-phonation-physical-experiment-and-theoretical-study
#17
Isao T Tokuda, Ryo Shimamura
As an alternative factor to produce asymmetry between left and right vocal folds, the present study focuses on level difference, which is defined as the distance between the upper surfaces of the bilateral vocal folds in the inferior-superior direction. Physical models of the vocal folds were utilized to study the effect of the level difference on the phonation threshold pressure. A vocal tract model was also attached to the vocal fold model. For two types of different models, experiments revealed that the phonation threshold pressure tended to increase as the level difference was extended...
August 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28857841/vocal-fold-leukoplakia-incidence-management-and-prevention
#18
Noah P Parker
PURPOSE OF REVIEW: The purpose of this article is to provide an update on English-language literature evaluating the current understanding of incidence, management, and prevention of vocal fold leukoplakia focusing on premalignancy. RECENT FINDINGS: Recent studies have continued to try to elucidate factors influencing recurrence and progression of dysplastic disease, though results vary. Although advanced diagnostic techniques have attempted to predict disease behavior, tissue diagnosis continues to be essential...
August 28, 2017: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/28857840/voice-rest-after-laryngeal-surgery-what-s-the-evidence
#19
Mami Kaneko, Shigeru Hirano
PURPOSE OF REVIEW: This article aims to review previous research reports and to summarize current strategies for the optimal duration of voice rest and the effect of phonatory stimulation after phonomicrosurgery. RECENT FINDINGS: Voice rest is commonly recommended after laryngeal surgery to prevent worsening of vocal fold injuries. However, there are no established standard protocol for voice rest, and the type and duration of voice rest vary among clinicians. The most effective duration of voice rest is unknown...
August 28, 2017: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/28852841/association-of-breathing-sound-spectra-with-glottal-dimensions-in-exercise-induced-vocal-cord-dysfunction
#20
Ahmed Geneid, L-M Aaltonen, L Porra, J Peltonen, K Palmu, A Sovijärvi, P Piirilä
The objective of this study was to evaluate associations between the breathing sound spectra and glottal dimensions in exercise-induced vocal cord dysfunction (EIVCD) during a bicycle ergometry test. Nineteen subjects (mean age 21.8 years and range 13-39 years) with suspected EIVCD were studied. Vocal folds were continuously imaged with videolaryngoscopy and breathing sounds were recorded during the bicycle exercise test. Twelve subjects showed paradoxical movement of the vocal folds during inspiration by the end of the exercise...
August 29, 2017: European Archives of Oto-rhino-laryngology
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