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https://www.readbyqxmd.com/read/29343628/keeping-the-home-fires-burning-amp-activated-protein-kinase
#1
REVIEW
D Grahame Hardie
Living cells obtain energy either by oxidizing reduced compounds of organic or mineral origin or by absorbing light. Whichever energy source is used, some of the energy released is conserved by converting adenosine diphosphate (ADP) to adenosine triphosphate (ATP), which are analogous to the chemicals in a rechargeable battery. The energy released by the conversion of ATP back to ADP is used to drive most energy-requiring processes, including cell growth, cell division, communication and movement. It is clearly essential to life that the production and consumption of ATP are always maintained in balance, and the AMP-activated protein kinase (AMPK) is one of the key cellular regulatory systems that ensures this...
January 2018: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/29341514/opportunity-costs-in-paediatric-training-the-specialist-registrars-experience
#2
M B O'Neill, T Nabialek, N Kandamany
In the training process, there is a tension between the work life and home life of trainees. This study explored both the personal impact and the opportunity costs of training from the Specialist Paediatric Registrar (SPR) perspective. The survey explored 1) career progression, 2) perceived functional effectiveness at work, 3) psychological impact of hospital based training, and 4) the personal and social cost of training. Fifty-three (71%) SPRs responded of whom 47 (89%)were married or in long term relationships...
August 8, 2017: Irish Medical Journal
https://www.readbyqxmd.com/read/29341191/working-and-caring-for-a-child-with-chronic-illness-a-review-of-current-literature
#3
A M Kish, P A Newcombe, D M Haslam
BACKGROUND: Advances in medical knowledge have contributed to the increase in the number of children living with some form of long-term chronic illness or condition. As a consequence of these advancements, treatments that are more accessible and easier to administer, usually within a child's home, have been developed. However, this may mean that parents take on greater treatment responsibility and require extra time and energy to meet these tasks, additional to other responsibilities...
January 16, 2018: Child: Care, Health and Development
https://www.readbyqxmd.com/read/29334939/choosing-a-career-in-oncology-results-of-a-nationwide-cross-sectional-study
#4
J C Faivre, J E Bibault, A Bellesoeur, J Salleron, M Wack, J Biau, M Cervellera, G Janoray, T Leroy, N Lescut, V Martin, S Molina, B Pichon, C Teyssier, S Thureau, J J Mazeron, H Roché, S Culine
BACKGROUND: Little information is currently available concerning young medical students desire to pursue a career in oncology, or their career expectations. METHODS: This project is a cross-sectional epidemiological study. A voluntary and anonymous questionnaire was distributed to all young oncologists studying in France between the 2nd of October 2013 and the 23rd of February 2014. RESULTS: The overall response rate was 75.6%. A total of 505 young oncologists completed the questionnaire...
January 15, 2018: BMC Medical Education
https://www.readbyqxmd.com/read/29327593/the-impact-of-age-and-gender-on-the-icf-based-assessment-of-chronic-low-back-pain
#5
Elisabeth Fehrmann, Simone Kotulla, Linda Fischer, Thomas Kienbacher, Kerstin Tuechler, Patrick Mair, Gerold Ebenbichler, Birgit Paul
PURPOSE: To evaluate the impact of age and gender on the international classification of functioning, disability and health (ICF)-based assessment for chronic low back pain. METHODS: Two hundred forty-four chronic low back pain patients (52% female) with a mean age of 49 years (SD =17.64) were interviewed with the comprehensive ICF core set for activities and participation, and environmental factors. After conducting explorative factor analysis, the impact of age and gender on the different factors was analyzed using analyzes of variances...
January 12, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29321015/differentials-in-health-related-quality-of-life-of-employed-and-unemployed-women-with-normal-vaginal-delivery
#6
Anthonia U Chinweuba, Ijeoma L Okoronkwo, Agnes N Anarado, Noreen E Agbapuonwu, Ngozi P Ogbonnaya, Chikaodili N Ihudiebube-Splendor
BACKGROUND: The combination of child care and domestic work demands on both housewives and the employed (hired) women may impact their health-related quality-of-life. There is paucity of studies to ascertain this. This study investigated the differences in health-related quality of life of employed and unemployed women with normal vaginal delivery and associated socio-demographic variables. METHODS: This longitudinal study was done from March, 2012 to June, 2013...
January 10, 2018: BMC Women's Health
https://www.readbyqxmd.com/read/29319445/development-of-a-taxonomy-of-practice-related-stressors-experienced-by-veterinarians-in-the-united-states
#7
Olivia H Vande Griek, Malissa A Clark, Tracy K Witte, Randall J Nett, Amanda N Moeller, Margaret E Stabler
OBJECTIVE To develop a comprehensive taxonomy of practice-related stressors experienced by US veterinarians. DESIGN Cross-sectional survey. SAMPLE A subset of 1,422 US veterinarians who provided written (vs selected) responses to a question in a previous survey regarding practice-related stressors. PROCEDURES Using grounded theory analysis, 3 researchers inductively analyzed written survey responses concerning respondents' main practice-related stressors. In 5 iterations, responses were individually coded and categorized, and a final list of practice-related stressor categories and subcategories was iteratively and collaboratively developed until theoretical and analytic saturation of the data was achieved...
January 15, 2018: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/29316334/geriatric-assessment-of-physical-and-cognitive-functioning-in-a-diverse-cohort-of-systemic-lupus-erythematosus-patients-a-pilot-study
#8
Laura Plantinga, Benjamin D Tift, Charmayne Dunlop-Thomas, S Sam Lim, C Barrett Bowling, Cristina Drenkard
OBJECTIVE: To use multi-domain functional assessment, commonly performed in geriatric patients but novel among SLE patients, to better understand functional impairment in SLE. METHODS: We recruited 60 adult participants [aged 20-39 (26.7%), 40-59 (50.0%), and ≥60 (23.3%); 80.0% black; 90.0% female] from an existing cohort of SLE patients. During in-person visits (10/16-4/17), we evaluated physical performance (range 0-4; higher scores = better performance); cognitive performance (five fluid cognition domains; adjusted t-scores); and self-reported measures including physical functioning (t-scores), activities of daily living (ADLs), falls, and life-space mobility...
January 5, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29315278/a-qualitative-study-of-hr-ohs-stress-interventions-in-australian-universities
#9
Silvia Pignata, Anthony H Winefield, Carolyn M Boyd, Chris Provis
To enhance the understanding of psychosocial factors and extend research on work stress interventions, we investigated the key human resource (HR)/occupational health and safety (OHS) stress interventions implemented at five Australian universities over a three-year period. Five senior HR Directors completed an online survey to identify the intervention strategies taken at their university in order to reduce stress and enhance employee well-being and morale. We also explored the types of individual-, organization-, and individual/organization-directed interventions that were implemented, and the strategies that were prioritized at each university...
January 9, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29311174/family-physicians-managing-medical-requests-from-family-and-friends
#10
Esther Giroldi, Robin Freeth, Maurice Hanssen, Jean W M Muris, Margareth Kay, Jochen W L Cals
PURPOSE: Although guidelines generally state that physicians should not treat their family members or friends (nonpatients), physicians regularly receive medical requests from nonpatients. We aimed to explore junior and senior family physicians' experiences with and attitudes toward managing medical requests from nonpatients. METHODS: We conducted a qualitative study with 7 focus groups with junior and senior physicians. We performed a thematic analysis during an iterative cycle of data collection and analysis...
January 2018: Annals of Family Medicine
https://www.readbyqxmd.com/read/29298882/host-tumor-suppressor-p18ink4c-functions-as-a-potent-cell-intrinsic-inhibitor-of-%C3%AE-hv68-reactivation-and-pathogenesis
#11
Brian F Niemeyer, Lauren M Oko, Eva M Medina, Darby G Oldenburg, Douglas W White, Carlyne D Cool, Eric T Clambey, Linda F van Dyk
Gammaherpesviruses are common viruses associated with lifelong infection and increased disease risk. Reactivation from latency aids the virus in maintaining infection throughout the life of the host and is responsible for a wide array of disease outcomes. Previously, we demonstrated that the virus encoded cyclin (v-cyclin) of murine gammaherpesvirus 68 (γHV68) is essential for optimal reactivation from latency in normal mice but not in mice lacking the host tumor suppressor, p18INK4c (p18). Whether p18 plays a cell-intrinsic or -extrinsic role in constraining reactivation remains unclear...
January 3, 2018: Journal of Virology
https://www.readbyqxmd.com/read/29290595/the-media-response-to-the-acgme-s-2017-relaxed-resident-duty-hour-restrictions
#12
Zi Zhang, Alan V Krauthamer, Andrew B Rosenkrantz
PURPOSE: In March 2017, the ACGME relaxed resident duty-hour restrictions to allow first-year residents to work 24-hour shifts, affecting the internship experience of incoming radiology residents. The aim of this study was to assess the media response to this duty-hour change, comparing news articles with favorable and unfavorable views. METHODS: Google News was used to identify 36 relevant unique news articles published over a 4-week period after the announcement...
December 28, 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29289752/maintaining-the-fire-but-avoiding-burnout-implementation-and-evaluation-of-a-resident-well-being-program
#13
Taylor S Riall, Joshua Teiman, Michelle Chang, Denzel Cole, Tambre Leighn, Hilary McClafferty, Valentine N Nfonsam
BACKGROUND: There have been few programs designed to improve surgical resident wellbeing and such efforts often lack formal evaluation. STUDY DESIGN: General Surgery residents participated in the Energy Leadership Wellbeing and Resiliency Program. They were assessed at baseline and one year after implementation using the Energy Leadership Index (ELI, measures emotional intelligence), Maslach Burnout Inventory (MBI) General Survey, Perceived Stress Scale (PSS), the Beck Depression Inventory (BDI), and the annual required ACGME resident survey...
December 28, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/29280446/burnout-evaluation-of-radiation-residents-nationwide-results-of-a-survey-of-united-states-residents
#14
Stephen J Ramey, Awad A Ahmed, Cristiane Takita, Lynn D Wilson, Charles R Thomas, Raphael Yechieli
PURPOSE: To assess rates of burnout among US radiation oncology residents and evaluate program/resident factors associated with burnout. METHODS AND MATERIALS: A nationwide survey was distributed to residents in all US radiation oncology programs. The survey included the Maslach Burnout Index-Human Services Survey (MBI-HSS) as well as demographic and program-specific questions tailored to radiation oncology residents. Primary endpoints included rates of emotional exhaustion, depersonalization, and personal accomplishment from MBI-HSS subscale scores...
November 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29279456/exploring-attractiveness-of-the-basic-sciences-for-female-physicians
#15
Yuka Yamazaki, Shinji Fukushima, Yuki Kozono, Takanori Uka, Eiji Marui
In Japan, traditional gender roles of women, especially the role of motherhood, may cause early career resignations in female physicians and a shortage of female researchers. Besides this gender issue, a general physician shortage is affecting basic science fields. Our previous study suggested that female physicians could be good candidates for the basic sciences because such work offers good work-life balance. However, the attractiveness for female physicians of working in the basic sciences, including work-life balance, is not known...
2018: Tohoku Journal of Experimental Medicine
https://www.readbyqxmd.com/read/29279235/attitudes-toward-working-conditions-are-european-union-workers-satisfied-with-their-working-hours-and-work-life-balance
#16
Nuria Matilla-Santander, Cristina Lidón-Moyano, Adrián González-Marrón, Kailey Bunch, Juan Carlos Martín-Sánchez, José M Martínez-Sánchez
OBJECTIVE: To describe the satisfaction with working hours and satisfaction with work-life balance and their association in the European Union (EU-28). METHOD: This is a cross-sectional study based on data from the Flash Eurobarometer 398 among workers of the EU-28 from 2014 (n=13,683). We calculated percentages and their 95% confidence intervals (95%CI). We also applied a multi-level generalised linear model using the Poisson family, to calculate the adjusted prevalence ratios (aPR) of satisfaction with work-life balance based on working hours...
December 23, 2017: Gaceta Sanitaria
https://www.readbyqxmd.com/read/29277025/fatigue-quality-of-life-and-walking-ability-in-adults-with-cerebral-palsy
#17
Sofia Lundh, Salmir Nasic, Jacques Riad
INTRODUCTION: Few studies on fatigue, quality of life and walking ability in adults with cerebral palsy (CP) are available. It is unclear whether these variables are associated. AIM: The aim was to study the influence of CP on fatigue, quality of life, and gait of adult patients. MATERIAL AND METHODS: Three-dimensional gait analysis was performed on 24 women and 26 men, mean age 32.1 (range 21.7-67.2), 23 with unilateral and 27 with bilateral CP...
December 16, 2017: Gait & Posture
https://www.readbyqxmd.com/read/29276304/women-s-employment-patterns-after-childbirth-and-the-perceived-access-to-and-use-of-flexitime-and-teleworking
#18
Heejung Chung, Mariska van der Horst
This article sets out to investigate how flexitime and teleworking can help women maintain their careers after childbirth. Despite the increased number of women in the labour market in the UK, many significantly reduce their working hours or leave the labour market altogether after childbirth. Based on border and boundary management theories, we expect flexitime and teleworking can help mothers stay employed and maintain their working hours. We explore the UK case, where the right to request flexible working has been expanded quickly as a way to address work-life balance issues...
January 2018: Human Relations; Studies Towards the Integration of the Social Sciences
https://www.readbyqxmd.com/read/29276292/formation-of-a-citywide-pharmacy-residents-collaborative-committee
#19
Jonathan H Sin, Jamie Chin, Loriel J Solodokin
Pharmacy residents undergo rigorous training to become skillful and knowledgeable independent practitioners. In addition to delivering direct clinical and operational pharmacy services, residents also participate in various administrative, educational, and scholarly activities as part of their residency experience. Throughout their training, residents may rely on individuals within their network for professional, personal, and emotional support, including residency program directors, preceptors, and co-residents from their respective institutions...
September 2017: Hospital Pharmacy
https://www.readbyqxmd.com/read/29273629/do-flexible-work-policies-improve-parent-s-health-a-natural-experiment-based-on-the-uk-millennium-cohort-study
#20
Mauricio Avendano, Lidia Panico
BACKGROUND: There is limited evidence of the impact of policies to promote work-family balance on family health. Exploiting the introduction of the UK Flexible Working Act (2003), we examined whether a policy that grants parents the right to request flexible work influences their health and well-being. METHODS: Using the UK Millennium Cohort Study, we focus on 6424 mothers employed in 2001-2002, when the cohort child was 9 months old, until their child's seventh birthday...
December 22, 2017: Journal of Epidemiology and Community Health
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