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Pedro Pereira, Filipe Vilas-Boas, Armando Peixoto, Patrícia Andrade, Joanne Lopes, Guilherme Macedo
Introduction: Cholangiopancreatoscopy with SpyGlass™ Direct Visualization System (SGDVS) is being used in specialized centers for improving the sensitivity of endoscopic retrograde cholangiopancreatography (ERCP) in patients with indeterminate pancreatobiliary strictures (PBS). The aims of this study were to report our initial experience with SGDVS in the evaluation of indeterminate PBS, and discuss the improvements of ERCP brought by this technique in our center. Methods: The usefulness of SGDVS in patients with indeterminate PBS (defined after nondiagnostic previous ERCP with brush cytology) was evaluated in a prospective observational cohort study conducted at a single tertiary biliopancreatic unit...
April 2018: GE Portuguese Journal of Gastroenterology
Marta Gravito-Soares, Nuno Almeida
No abstract text is available yet for this article.
April 2018: GE Portuguese Journal of Gastroenterology
Felicia Turowski, Ulrich Hügle, Arno Dormann, Matthias Bechtler, Ralf Jakobs, Uwe Gottschalk, Ellen Nötzel, Dirk Hartmann, Albrecht Lorenz, Frank Kolligs, Wilfried Veltzke-Schlieker, Andreas Adler, Olaf Becker, Bertram Wiedenmann, Nataly Bürgel, Hanno Tröger, Michael Schumann, Severin Daum, Britta Siegmund, Christian Bojarski
BACKGROUND AND AIMS: The aim of the study was to evaluate the usefulness and diagnostic and therapeutic outcome of the single-operator cholangiopancreatoscopy (SOC) with SpyGlassDS™. METHODS: In a retrospective multicenter study between November 2015 and January 2017, SpyGlassDS™ procedures were analyzed in participating centers. Indications, accuracy of SOC-guided biopsies, management of large bile duct stones, and complications were analyzed. Follow-up was 4 months...
March 12, 2018: Surgical Endoscopy
Meir Mizrahi, Tawfik Khoury, Yan Wang, Jonah Cohen, Jennifer Sheridan, Ram Chuttani, Tyler M Berzin, Mandeep S Sawhney, Douglas K Pleskow
BACKGROUND: While the fiberoptic single-operator cholangiopancreatoscopy (FSOCP) system has demonstrated efficacy in the diagnosis and management of pancreaticobiliary diseases, the digital SOCP (DSOCP) appears to provide higher resolution digital imaging, however a comparison of these devices has not been established. The aim of this work was to compare the efficacy of FSOCP and DSOCP in biliary stone disease and indeterminate biliary strictures. METHODS: A retrospective analysis of a prospective cohort was performed in patients undergoing FSOCP or DSOCP demographics included indication, diagnostic yield, procedure time, radiation dose, and complications...
October 26, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
Pedro Pereira, Armando Peixoto, Patrícia Andrade, Guilherme Macedo
Smaller endoscopes and catheters have been developed that permit direct visualization of the bile and pancreatic ducts (cholangioscopy and pancreatoscopy, respectively). These endoscopes and catheters are passed through the working channel of a standard therapeutic duodenoscope during endoscopic retrograde cholangiopancreatography (ERCP). The SpyGlass Direct Visualization System (Boston Scientific Corp, Natick, MA, USA) is currently the most widely used and studied device. Cholangioscopy with intraductal lithotripsy has become an established modality in the treatment of difficult biliary lithiasis...
June 2017: Journal of Gastrointestinal and Liver Diseases: JGLD
Alena Ondrejková, Bohuslav Kianička, Hana Nechutová, Lukáš Hruška, Ivo Novotný, Miroslav Souček
Autoimmune pancreatitis (AIP) is a rare form of chronic pancreatitis, classified into 2 subtypes - AIP type 1 and AIP type 2. We present a case of a 31-years-old female admitted to our institution with upper abdominal pain and obstructive jaundice. Endoscopic retrograde cholangiopancreatoscopy (ERCP) revealed stenosis of intrapancreatic distal bile duct. Diffuse parenchymal enlargement and typical features of AIP were shown by computed tomography (CT) and endoscopic ultrasonography (EUS). The patient´s serum IgG4 was elevated at 3...
December 0: Vnitr̆ní Lékar̆ství
Raj J Shah, Isaac Raijman, Brian Brauer, Bora Gumustop, Douglas K Pleskow
Background and study aim Our aim was to evaluate the first use in humans of a new, single-use, digital, single-operator intraductal cholangiopancreatoscopy system (IDCP). Patients and methods Data were collected retrospectively from four US institutions between February 2015 and April 2015. The visual impression of neoplasia or benign findings with IDCP was determined by the performing endoscopist. High grade dysplasia, intraductal papillary mucinous neoplasm, neuroendocrine tumor, and malignancy were categorized as neoplasia...
July 2017: Endoscopy
Nikhil Banerjee, Mayur Parepally, T Karl Byrne, Rana C Pullatt, Gregory A Coté, B Joseph Elmunzer
Balloon-assisted endoscopic retrograde cholangiopancreatoscopy (ERCP) in Roux-en-Y gastric bypass (RYGB) patients is technically challenging due to anatomic and accessory constraints, thus success rates are modest. Transgastric ERCP (TG-ERCP) offers a viable alternative. We aimed to systematically review the literature on TG-ERCP in RYGB patients to better define the technical approaches, success rates, and adverse events of this procedure. A computer-assisted search of the Embase and PubMed databases was performed to identify studies that focused on the techniques and clinical outcomes of TG-ERCP...
July 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
Rawad Mounzer, Gregory L Austin, Sachin Wani, Brian C Brauer, Norio Fukami, Raj J Shah
BACKGROUND AND AIMS: Cholangiopancreatoscopy for evaluating pancreaticobiliary pathology is currently limited by suboptimal optics. The aim of this study was to characterize the operating characteristics of per-oral video cholangiopancreatoscopy with narrow-band imaging (POVCP) findings in indeterminate pancreaticobiliary disease and to describe their association with neoplasia. METHODS: Data from consecutive patients undergoing POVCP for the evaluation of indeterminate pancreaticobiliary disease at a single tertiary care center were analyzed...
March 2017: Gastrointestinal Endoscopy
Sri Komanduri, Nirav Thosani, Barham K Abu Dayyeh, Harry R Aslanian, Brintha K Enestvedt, Michael Manfredi, John T Maple, Udayakumar Navaneethan, Rahul Pannala, Mansour A Parsi, Zachary L Smith, Shelby A Sullivan, Subhas Banerjee
No abstract text is available yet for this article.
August 2016: Gastrointestinal Endoscopy
Udayakumar Navaneethan, Muhammad K Hasan, Kiran Kommaraju, Xiang Zhu, Shantel Hebert-Magee, Robert H Hawes, John J Vargo, Shyam Varadarajulu, Mansour A Parsi
BACKGROUND AND AIMS: Digital cholangioscopes provide higher-resolution imaging of the pancreatobiliary tract compared with fiberoptic instruments. The role of a new, digital, single-operator cholangiopancreatoscopy (SOC) system for diagnosis and treatment of pancreatobiliary disorders in clinical practice is not known. METHODS: We performed a multicenter, observational study of 105 consecutive patients with suspected pancreatobiliary disorders. The main outcome measures were (1) sensitivity and specificity of SOC visual appearance and biopsies in the diagnosis of indeterminate biliary strictures and (2) achieving complete duct clearance in patients with biliary or pancreatic duct stones...
October 2016: Gastrointestinal Endoscopy
Toshio Kurihara, Ichiro Yasuda, Hiroyuki Isayama, Toshio Tsuyuguchi, Taketo Yamaguchi, Ken Kawabe, Yoshinobu Okabe, Keiji Hanada, Tsuyoshi Hayashi, Takao Ohtsuka, Syuhei Oana, Hiroshi Kawakami, Yoshinori Igarashi, Kazuya Matsumoto, Kiichi Tamada, Shomei Ryozawa, Hiroki Kawashima, Yutaka Okamoto, Iruru Maetani, Hiroyuki Inoue, Takao Itoi
AIM: To assess the utility and safety of single-operator cholangiopancreatoscopy (SOCPS) using the SpyGlass system in widespread clinical application for biliary and pancreatic diseases. METHODS: This study was a prospective case series conducted in 20 referral centers in Japan. There were 148 patients who underwent SOCPS; 124 for biliary diseases and 24 for pancreatic diseases. The attempted interventions were SOCPS examination, SOCPS-directed tissue sampling, and therapy for stone removal, among others...
February 7, 2016: World Journal of Gastroenterology: WJG
Reina Tanaka, Takao Itoi, Mitsusyoshi Honjo, Takayoshi Tsuchiya, Toshio Kurihara, Shujiro Tsuji, Ryosuke Tonozuka, Kentato Kamada, Atsushi Sofuni, Shuntaro Mukai
BACKGROUND: Recently, a new digital cholangiopancreatoscopy (DCPS) has been developed. The aim of this study is to retrospectively evaluate the utility of new DCPS in patients with pancreaticobiliary diseases. METHODS: Digital cholangiopancreatoscopy was used in 26 patients (16 men) with pancreaticobiliary diseases that could not be diagnosed and treated by standard endoscopic retrograde cholangiopancreatography (ERCP). The procedures included DCPS-guided tissue sampling and interventions...
April 2016: Journal of Hepato-biliary-pancreatic Sciences
Ari F Syam, Syahidatul Wafa, Dadang Makmun
A fifty-five year old female patient presented with jaundice, subfebrile fever and dark yellow urine since one month before admission. She lost weight 10 kilograms during one month. One day before admission to Ciptomangunkusumo General Hospital, she complained of worsened abdominal pain at right upper quadrant urging her to come to the emergency room. An abdominal examination revealed Murphy sign, mild hepatomegaly and deeply icteric sclera. Serum bilirubin was 21.8 mg/dl, alkaline phosphatase and gamma-glutamyltransferase levels were significantly elevated (1090 IU/L and 560 IU/L consecutively) while the transaminases were moderately high (ALT 80 U/L)...
April 2015: Acta Medica Indonesiana
D G Adler, K Cox, M Milliken, L J Taylor, D Loren, T Kowalski, G Francis, S N Laique, A Siddiqui
AIM: Cholangiopancreatoscopy (CP) is an endoscopic technique that allows for direct visualization of the biliary and pancreatic ducts using a narrow caliber endoscope that passes through the working channel of a duodenoscope directly into the bile and/or pancreatic ducts. Little data is available on the safety of CP. We performed a multicenter retrospective study to evaluate the frequency and severity of adverse events with single operator CP. METHODS: A multicenter retrospective study was conducted...
December 2015: Minerva Gastroenterologica e Dietologica
Mohan Ramchandani, Duvvur Nageshwar Reddy, Sundeep Lakhtakia, Manu Tandan, Amit Maydeo, Thoguluva Seshadri Chandrashekhar, Ajay Kumar, Randhir Sud, Rungsun Rerknimitr, Dadang Makmun, Christopher Khor
AIM: To provide consensus statements on the use of per-oral cholangiopancreatoscopy (POCPS). METHODS: A workgroup of experts in endoscopic retrograde cholangiopancreatography (ERCP), endosonography, and POCPS generated consensus statements summarizing the utility of POCPS in pancreaticobiliary disease. Recommendation grades used validated evidence ratings of publications from an extensive literature review. RESULTS: Six consensus statements were generated: (1) POCPS is now an important additional tool during ERCP; (2) in patients with indeterminate biliary strictures, POCS and POCS-guided targeted biopsy are useful for establishing a definitive diagnosis; (3) POCS and POCS-guided lithotripsy are recommended for treatment of difficult common bile duct stones when standard techniques fail; (4) in patients with main duct intraductal papillary mucinous neoplasms (IPMN) POPS may be used to assess extent of tumor to assist surgical resection; (5) in difficult pancreatic ductal stones, POPS-guided lithotripsy may be useful in fragmentation and extraction of stones; and (6) additional indications for POCPS include selective guidewire placement, unexplained hemobilia, assessing intraductal biliary ablation therapy, and extracting migrated stents...
April 21, 2015: World Journal of Gastroenterology: WJG
Alan H Tieu, Vivek Kumbhari, Neha Jakhete, Frances Onyimba, Yuval Patel, Eun Ji Shin, Zhiping Li
BACKGROUND AND AIM: SpyGlass® cholangiopancreatoscopy system has shown early success in aiding diagnosis and management of pancreaticobiliary diseases. We aimed to assess the technical success, clinical success, diagnostic yield, therapeutic yield, and safety of the SpyGlass® system at a single institution. METHODS: A retrospective, single-center review of consecutive patients who underwent endoscopic retrograde cholangiopancreatography with SpyGlass® between January 2008 and August 2013 for a variety of indications...
May 2015: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
Wesley B Jones, Joseph Blackwell, Brian McKinley, Steven Trocha
Many surgeons prefer to perform endoscopic retrograde cholangiopancreatography (ERCP) before cholecystectomy, specifically in patients at significant risk of having biliary pathology. However, a preoperative diagnostic ERCP, without the use of an endoscopic ultrasound or magnetic retrograde cholangiopancreatoscopy, remains controversial. This is the result of the risk of either performing an unnecessary procedure and/or the development of post-ERCP pancreatitis (PEP). We performed a retrospective review of all surgeon-performed ERCPs at our institution between July 2011 and May 2013...
August 2014: American Surgeon
Mansour A Parsi, Sunguk Jang, Madhusudhan Sanaka, Tyler Stevens, John J Vargo
BACKGROUND: High-definition cholangioscopes provide excellent images of the pancreatobiliary ductal system and may play a significant role in diagnosis and treatment of various pancreatobiliary disorders. OBJECTIVE: To assess the performance of a new digital cholangioscope for diagnosis and treatment of pancreatobiliary disorders in clinical practice. DESIGN: Prospective study. SETTING: Academic hospital, tertiary-care referral center...
June 2014: Gastrointestinal Endoscopy
Jürgen Glatz, P Beatriz Garcia-Allende, Valentin Becker, Maximilian Koch, Alexander Meining, Vasilis Ntziachristos
BACKGROUND: The recent clinical propagation of targeted fluorescence agents brings a promising alternative in endoscopy by complementing visual disease detection with molecular biomarkers. OBJECTIVE: Development of near-infrared (NIR) fluorescence cholangiopancreatoscopy in real-time and validation of its clinical use. DESIGN: Feasibility study. SETTING: Tertiary referral center at a large university hospital. PATIENTS: Patients with pancreatic and biliary diseases...
April 2014: Gastrointestinal Endoscopy
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