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https://www.readbyqxmd.com/read/28406727/the-experience-of-patients-with-alcohol-misuse-after-surviving-a-critical-illness-a-qualitative-study
#1
Brendan J Clark, Jacqueline Jones, K Diandra Reed, Rachel Marie Hodapp, Ivor S Douglas, David Van Pelt, Ellen L Burnham, Marc Moss
RATIONALE: Alcohol misuse is common in patients admitted to the intensive care unit (ICU) but there is currently no evidence-based approach to address drinking in ICU survivors. OBJECTIVES: We sought to describe the experience of ICU survivors with alcohol misuse during their hospitalization and the 3 months following hospital discharge in order to inform an alcohol specific intervention for this unique population. METHODS: We conducted a descriptive qualitative study of ICU survivors from medical ICUs in three separate hospitals with a positive screening result on the Alcohol Use Disorders Identification Test...
April 13, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28358883/-r%C3%A3-anet-the-internet-utilization-among-surrogates-of-critically-ill-patients-with-sepsis
#2
Yên-Lan Nguyen, Raphaël Porcher, Laurent Argaud, Lise Piquilloud, Christophe Guitton, Fabienne Tamion, Sami Hraiech, Jean-Paul Mira
CONTEXT: Health-related Internet utilization is common but its use by proxies of critically ill patients is unknown. Our objective was to describe the prevalence and the Internet utilization characteristics among surrogates of critically ill septic patients. We conducted a prospective observational study in French ICUs. Three survey instruments were used to describe ICU organization regarding information delivery, patients and surrogates characteristics. RESULTS: 169 surrogates of 146 septic patients hospitalized in 19 ICUs were included...
2017: PloS One
https://www.readbyqxmd.com/read/28349714/intoxications-involving-acrylfentanyl-and-other-novel-designer-fentanyls-results-from-the-swedish-strida-project
#3
Anders Helander, Matilda Bäckberg, Patrick Signell, Olof Beck
BACKGROUND: The number of new psychoactive substances (NPS) introduced through the online recreational drugs market increases continuously. This report from the Swedish STRIDA project describes analytically confirmed intoxications involving the novel fentanyl analogs acrylfentanyl, 4-chloroisobutyrfentanyl (4Cl-iBF), 4-fluoroisobutyrfentanyl (4F-iBF), and tetrahydrofuranfentanyl (THF-F), and cyclopentylfentanyl in a drug product. METHODS: Patients with suspected NPS exposure presenting in emergency departments (ED) or intensive care units (ICU) in Sweden and requiring hospital care are invited to the STRIDA project...
March 28, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28347296/the-effect-of-postal-questionnaire-burden-on-response-rate-and-answer-patterns-following-admission-to-intensive-care-a-randomised-controlled-trial
#4
Robert Hatch, Duncan Young, Vicki Barber, David A Harrison, Peter Watkinson
BACKGROUND: The effects of postal questionnaire burden on return rates and answers given are unclear following treatment on an intensive care unit (ICU). We aimed to establish the effects of different postal questionnaire burdens on return rates and answers given. METHODS: Design: A parallel group randomised controlled trial. We assigned patients by computer-based randomisation to one of two questionnaire packs (Group A and Group B). SETTING: Patients from 26 ICUs in the United Kingdom...
March 27, 2017: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/28338497/using-selective-serotonin-reuptake-inhibitors-and-serotonin-norepinephrine-reuptake-inhibitors-in-critical-care-a-systematic-review-of-the-evidence-for-benefit-or-harm
#5
John M Kelly, Gordon D Rubenfeld, Neil Masson, Arimie Min, Neill K J Adhikari
OBJECTIVE: Selective serotonin reuptake inhibitor/serotonin-norepinephrine reuptake inhibitors are among the most commonly prescribed drugs in patients admitted to the ICU. Our objective was to systematically review available literature for evidence of benefit or harm in ICU patients resulting from chronic effects, continued use, or withdrawal. DATA SOURCES: Medline, Embase, and Cochrane Central Register of Controlled Trials (1990 to November 2014). STUDY SELECTION: We searched for studies of ICU patients with recorded selective serotonin reuptake inhibitor/serotonin-norepinephrine reuptake inhibitor prescription before or during admission, and reporting morbidity, mortality, adverse events, and resource measures like ICU length of stay...
March 23, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28273613/relatives-perception-of-stressors-and-psychological-outcomes-results-from-a-survey-study
#6
Bastian Matt, Daniel Schwarzkopf, Konrad Reinhart, Christian König, Christiane S Hartog
PURPOSE: To identify relevant stressors or resources of relatives of critically ill patients and explore their relationship with psychological outcomes. MATERIALS AND METHODS: Prospective mixed-method study performed in 4 multidisciplinary ICUs of an urban academic hospital. Main relatives of consecutive patients with severe sepsis were questioned after 90days by structured interview. Quantitative data included demographic characteristics, ICU experience, Impact-of-Event Scale (posttraumatic stress) and Hospital Anxiety and Depression Scale (HADS); answers to open questions about stressors and resources were transcribed verbatim and analyzed by thematic analysis...
June 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28263377/the-frailty-phenotype-and-palliative-care-needs-of-older-survivors-of-critical-illness
#7
Lauren R Pollack, Nathan E Goldstein, Wendy C Gonzalez, Craig D Blinderman, Mathew S Maurer, David J Lederer, Matthew R Baldwin
OBJECTIVES: To assess symptoms in older intensive care unit (ICU) survivors and determine whether post-ICU frailty identifies those with the greatest palliative care needs. DESIGN: A prospective cohort study. SETTING: Urban tertiary care hospital and community hospital. PARTICIPANTS: Medical ICU survivors of mechanical ventilation aged 65 and older (N = 125). MEASUREMENTS: Baseline measurements of the Edmonton Symptom Assessment Scale (ESAS), categorized as mild (0-3), moderate (4-6), and severe (7-10), and the frailty phenotype were made during the week before hospital discharge...
March 6, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28197680/effect-of-a-condolence-letter-on-grief-symptoms-among-relatives-of-patients-who-died-in-the-icu-a-randomized-clinical-trial
#8
Nancy Kentish-Barnes, Sylvie Chevret, Benoît Champigneulle, Marina Thirion, Virginie Souppart, Marion Gilbert, Olivier Lesieur, Anne Renault, Maïté Garrouste-Orgeas, Laurent Argaud, Marion Venot, Alexandre Demoule, Olivier Guisset, Isabelle Vinatier, Gilles Troché, Julien Massot, Samir Jaber, Caroline Bornstain, Véronique Gaday, René Robert, Jean-Philippe Rigaud, Raphaël Cinotti, Mélanie Adda, François Thomas, Laure Calvet, Marion Galon, Zoé Cohen-Solal, Alain Cariou, Elie Azoulay
PURPOSE: Family members of patients who die in the intensive care unit (ICU) may experience symptoms of stress, anxiety, depression, posttraumatic stress disorder (PTSD), and/or prolonged grief. We evaluated whether grief symptoms were alleviated if the physician and the nurse in charge at the time of death sent the closest relative a handwritten condolence letter. METHODS: Multicenter randomized trial conducted among 242 relatives of patients who died at 22 ICUs in France between December 2014 and October 2015...
February 14, 2017: Intensive Care Medicine
https://www.readbyqxmd.com/read/28188064/the-impact-of-the-patient-post-intensive-care-syndrome-components-upon-caregiver-burden
#9
J Torres, D Carvalho, E Molinos, C Vales, A Ferreira, C C Dias, R Araújo, E Gomes
OBJECTIVE: To evaluate patient post-intensive care syndrome (PICS-P) and caregiver burden 3 months after discharge from the Intensive Care Unit (ICU) and determine the impact of different components of PICS-P upon caregiver burden. DESIGN: A prospective observational study was conducted over 26 months (January 2013-February 2015). SETTING: Medical-surgical ICU and follow-up consultation in Portugal. PATIENTS OR PARTICIPANTS: Patients discharged after a minimum of 2 days in the ICU...
February 7, 2017: Medicina Intensiva
https://www.readbyqxmd.com/read/28174662/psychological-rumination-and-recovery-from-work-in-intensive-care-professionals-associations-with-stress-burnout-depression-and-health
#10
Tushna Vandevala, Louisa Pavey, Olga Chelidoni, Nai-Feng Chang, Ben Creagh-Brown, Anna Cox
BACKGROUND: The work demands of critical care can be a major cause of stress in intensive care unit (ICU) professionals and lead to poor health outcomes. In the process of recovery from work, psychological rumination is considered to be an important mediating variable in the relationship between work demands and health outcomes. This study aimed to extend our knowledge of the process by which ICU stressors and differing rumination styles are associated with burnout, depression and risk of psychiatric morbidity among ICU professionals...
2017: Journal of Intensive Care
https://www.readbyqxmd.com/read/28168730/continuous-lidocaine-infusion-as-adjunctive-analgesia-in-intensive-care-unit-patients
#11
Yoonsun Mo, Michael C Thomas, Abigail D Antigua, Alex M Ebied, George E Karras
Despite a paucity of data, the role of intravenous lidocaine (IVLI) as adjunctive analgesia in the intensive care unit (ICU) seems promising due to a low potential to contribute to respiratory depression. A retrospective chart review was conducted to evaluate the safety and effectiveness of IVLI for the treatment of pain in ICU patients with varying degrees of organ dysfunction from March 2014 to March 2016. The primary outcomes included the time to a ≥20% reduction in pain scores after the initiation of IVLI and the difference in opioid requirements as well as pain scores prior to and during IVLI therapy...
February 7, 2017: Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28127828/psychiatric-symptomatology-after-delirium-a-systematic-review
#12
REVIEW
Clare Langan, Deep P Sarode, Tom C Russ, Susan D Shenkin, Alan Carson, Alasdair M J Maclullich
Delirium is an acute and usually transient severe neuropsychiatric syndrome associated with significant long-term physical morbidity. However, its chronic psychiatric sequelae remain poorly characterized. To investigate the prevalence of psychiatric symptoms, namely anxiety, depressive, and post-traumatic stress disorder (PTSD) symptoms after delirium, a systematic literature search of MEDLINE, EMBASE and PsycINFO databases was performed independently by two authors in March 2016. Bibliographies were hand-searched, and a forward- and backward-citation search using Web of Science was performed for all included studies...
January 27, 2017: Psychogeriatrics: the Official Journal of the Japanese Psychogeriatric Society
https://www.readbyqxmd.com/read/28110639/amitraz-poisoning-a-case-report-of-an-unusual-pesticide-poisoning-in-sri-lanka-and-literature-review
#13
H M M T B Herath, S P Pahalagamage, Nilukshana Yogendranathan, M D M S Wijayabandara, Aruna Kulatunga
BACKGROUND: Amitraz is a pesticide used worldwide on animals and in agriculture. It contains triazapentadiene, which is a centrally acting alpha-2 adrenergic agonist. Amitraz poisoning is fairly uncommon in humans and occurs via oral, dermal or inhalational routes. Only a limited number of case reports of human intoxication have been published and most of them are of accidental ingestion by children. CASE PRESENTATION: A twenty-year-old Sri Lankan female presented following self-ingestion of 20 ml of amitraz resulting in 37...
January 23, 2017: BMC Pharmacology & Toxicology
https://www.readbyqxmd.com/read/28065973/is-potassium-thiosulfate-a-poison-is-it-safe-a-case-series
#14
Cigdem Ozpolat, Arzu Denizbasi, Ozge Onur, Serkan Emre Eroglu, Haldun Akoglu
Potassium Thiosulfate is a liquid substance used for producing fertilizers. In this case series, we present five patients who have been exposed to potassium thiosulfate inhalation. Three of them were intubated in the scene by paramedics because of confusion and respiratory depression. They had refractory status epilepticus. The other two were exposed during trying to help the others for getting out, they presented to ED with nausea, vomiting and headache. One of the intubated patients died on the 4th day of his follow-up at ICU...
January 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28050894/patients-with-preexisting-psychiatric-disorders-admitted-to-icu-a-descriptive-and-retrospective-cohort-study
#15
Arnaud Gacouin, Adel Maamar, Pierre Fillatre, Emmanuelle Sylvestre, Margaux Dolan, Yves Le Tulzo, Jean Marc Tadié
BACKGROUND: While the psychiatric disorders are conditions frequently encountered in hospitalized patients, there are little or no data regarding the characteristics and short- and long-term outcomes in patients with preexisting psychiatric disorders in ICU. Such assessment may provide the opportunity to determine the respective impact on mortality in the ICU and after ICU discharge with reasons for admission, including modalities of self-harm, of underlying psychiatric disorders and prior psychoactive medications...
December 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28032249/anxiety-and-depressive-symptoms-among-two-seriously-medically-ill-populations-and-their-family-caregivers-a-comparison-and-clinical-implications
#16
Kelly M Shaffer, Jamie M Jacobs, Jessica N Coleman, Jennifer S Temel, Jonathan Rosand, Joseph A Greer, Ana-Maria Vranceanu
BACKGROUND: Anxiety and depression are common among patients with acute illness and their families. In oncology, psychosocial services addressing these symptoms are increasingly part of regular practice. Less is known about psychiatric distress among patients with acute neurological injury (ANI) and their family caregivers. To highlight this inequity in psychosocial intervention across medical services, we compared anxiety and depressive symptomatology shortly following diagnosis among patients facing incurable cancer or ANI and their family caregivers...
December 28, 2016: Neurocritical Care
https://www.readbyqxmd.com/read/27938775/a-woman-in-her-60s-with-fever-and-altered-mental-status-in-a-psychiatric-hospital
#17
Benjamin C Kalivas, Andrew J Goodwin
A woman in her 60s with a history of hepatitis C with cirrhosis and major depressive disorder with psychotic features was admitted to the inpatient psychiatric unit for suicidal ideation. She was initially treated with a combination of sertraline and paliperidone. The paliperidone was subsequently changed to risperidone and ultimately to olanzapine. She developed worsening mental status and was then treated for catatonia with benzodiazepines. Over 2 days, her mental status continued to worsen and she developed fever and tachycardia...
December 2016: Chest
https://www.readbyqxmd.com/read/27923935/radiographic-mastoid-and-middle-ear-effusions-in-intensive-care-unit-subjects
#18
Phillip Huyett, Yael Raz, Barry E Hirsch, Andrew A McCall
BACKGROUND: This study was conducted to determine the incidence of and risk factors associated with the development of radiographic mastoid and middle ear effusions (ME/MEE) in ICU patients. METHODS: Head computed tomography or magnetic resonance images of 300 subjects admitted to the University of Pittsburgh Medical Center neurologic ICU from April 2013 through April 2014 were retrospectively reviewed. Images were reviewed for absent, partial, or complete opacification of the mastoid air cells and middle ear space...
December 6, 2016: Respiratory Care
https://www.readbyqxmd.com/read/27903206/long-term-outcomes-after-severe-drug-overdose
#19
Lee Y Wong, Rinaldo Bellomo, Ray Robbins, Johan Martensson, Richard Kanaan, Richard Newton, Chih-Chiang Hu, David M Taylor
OBJECTIVE: The long-term outcomes of patients with drug overdose admitted to the intensive care unit compared with those admitted to general wards have not been assessed. We aimed to compare the recurrence of overdose, mortality after hospital discharge, cause of death and quality-of-life scores (using the EQ-5D questionnaire) between the ICU patients and general ward patients. METHODS: We performed a retrospective cohort study of 102 ICU patients with drug overdose and 102 matched general ward patients with drug overdose in a university-affiliated teaching hospital between 2009 and 2013...
December 2016: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/27885500/a-review-of-anaesthetic-outcomes-in-patients-with-genetically-confirmed-mitochondrial-disorders
#20
A Smith, E Dunne, M Mannion, C O'Connor, I Knerr, A A Monavari, J Hughes, N Eustace, E Crushell
Mitochondrial disorders are a clinically and biochemically diverse group of disorders which may involve multiple organ systems. General anaesthesia (GA) poses a potential risk of decompensation in children with mitochondrial disorders, and there is little guidance for anaesthetists and other clinicians regarding the optimal anaesthetic agents and perioperative management to provide to patients with mitochondrial disease[15]. The aim of this review was to document adverse events and perioperative complications from GA in patients with genetically confirmed mitochondrial disorders...
January 2017: European Journal of Pediatrics
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