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https://www.readbyqxmd.com/read/27903206/long-term-outcomes-after-severe-drug-overdose
#1
Lee Y Wong, Rinaldo Bellomo, Ray Robbins, Johan Martensson, Richard Kanaan, Richard Newton, Chih-Chiang Hu, David M Taylor
OBJECTIVE: The long-term outcomes of patients with drug overdose admitted to the intensive care unit compared with those admitted to general wards have not been assessed. We aimed to compare the recurrence of overdose, mortality after hospital discharge, cause of death and quality-of-life scores (using the EQ-5D questionnaire) between the ICU patients and general ward patients. METHODS: We performed a retrospective cohort study of 102 ICU patients with drug overdose and 102 matched general ward patients with drug overdose in a university-affiliated teaching hospital between 2009 and 2013...
December 2016: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/27885500/a-review-of-anaesthetic-outcomes-in-patients-with-genetically-confirmed-mitochondrial-disorders
#2
A Smith, E Dunne, M Mannion, C O'Connor, I Knerr, A A Monavari, J Hughes, N Eustace, E Crushell
: Mitochondrial disorders are a clinically and biochemically diverse group of disorders which may involve multiple organ systems. General anaesthesia (GA) poses a potential risk of decompensation in children with mitochondrial disorders, and there is little guidance for anaesthetists and other clinicians regarding the optimal anaesthetic agents and perioperative management to provide to patients with mitochondrial disease[15]. The aim of this review was to document adverse events and perioperative complications from GA in patients with genetically confirmed mitochondrial disorders...
November 24, 2016: European Journal of Pediatrics
https://www.readbyqxmd.com/read/27835704/preliminary-identification-of-coping-profiles-relevant-to-surrogate-decision-making-in-the-icu
#3
Jorie M Butler, Eliotte L Hirshberg, Ramona O Hopkins, Emily L Wilson, James F Orme, Sarah J Beesley, Kathryn Kuttler, Samuel M Brown
OBJECTIVE: The Intensive Care Unit (ICU) is a stressful environment for families of critically ill patients and these individuals are at risk to develop persistent psychological morbidity. Our study objective was to identify individual differences in coping with stress and information presentation preferences of respondents exposed to a simulated ICU experience. METHODS: Participants were recruited from a university and two community populations. Participants completed questionnaires that measured demographic information and characteristics that may be relevant to an individual's ICU experience...
2016: PloS One
https://www.readbyqxmd.com/read/27830281/a-family-information-brochure-and-dedicated-website-to-improve-the-icu-experience-for-patients-relatives-an-italian-multicenter-before-and-after-study
#4
Giovanni Mistraletti, Michele Umbrello, Elena Silvia Mantovani, Benedetta Moroni, Paolo Formenti, Paolo Spanu, Stefania Anania, Elisa Andrighi, Alessandra Di Carlo, Federica Martinetti, Irene Vecchi, Alessandra Palo, Cristina Pinna, Riccarda Russo, Silvia Francesconi, Federico Valdambrini, Enrica Ferretti, Giulio Radeschi, Edda Bosco, Paolo Malacarne, Gaetano Iapichino
PURPOSE: Good communication between ICU staff and patients' relatives may reduce the occurrence of post-traumatic stress disorder, anxiety or depression, and dissatisfaction with clinicians. An information brochure and website to meet relatives' needs were designed to explain in technical yet simple terms what happens during and after an ICU stay, to legitimize emotions such as fear, apprehension, and suffering, and to improve cooperation with relatives without increasing staff workload...
November 9, 2016: Intensive Care Medicine
https://www.readbyqxmd.com/read/27817882/does-early-beta-blockade-in-isolated-severe-traumatic-brain-injury-reduce-the-risk-of-post-traumatic-depression
#5
Rebecka Ahl, Gabriel Sjolin, Shahin Mohseni
INTRODUCTION: Depressive symptoms occur in approximately half of trauma patients, negatively impacting on functional outcome and quality of life following severe head injury. Pontine noradrenaline has been shown to increase upon trauma and associated β-adrenergic receptor activation appears to consolidate memory formation of traumatic events. Blocking adrenergic activity reduces physiological stress responses during recall of traumatic memories and impairs memory, implying a potential therapeutic role of β-blockers...
October 31, 2016: Injury
https://www.readbyqxmd.com/read/27798539/pediatric-minor-traumatic-brain-injury-with-intracranial-hemorrhage-identifying-low-risk-patients-who-may-not-benefit-from-icu-admission
#6
Erin Comer Burns, Beech Burns, Craig D Newgard, Amber Laurie, Rongwei Fu, Theresa Graif, Casey S Ward, Abbie Bauer, David Steinhardt, Laura M Ibsen, David M Spiro
BACKGROUND: Pediatric patients with any severity of traumatic intracranial hemorrhage (tICH) are often admitted to intensive care units (ICUs) for early detection of secondary injury. We hypothesize that there is a subset of these patients with mild injury and tICH for whom ICU care is unnecessary. OBJECTIVES: To quantify tICH frequency and describe disposition and to identify patients at low risk of inpatient critical care intervention (CCI). METHODS: We retrospectively reviewed patients aged 0 to 17 years with tICH at a single level I trauma center from 2008 to 2013...
October 28, 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27796253/anxiety-symptoms-in-survivors-of-critical-illness-a-systematic-review-and-meta-analysis
#7
REVIEW
Sina Nikayin, Anahita Rabiee, Mohamed D Hashem, Minxuan Huang, O Joseph Bienvenu, Alison E Turnbull, Dale M Needham
OBJECTIVES: To evaluate the epidemiology of and postintensive care unit (ICU) interventions for anxiety symptoms after critical illness. METHODS: We searched five databases (1970-2015) to identify studies assessing anxiety symptoms in adult ICU survivors. Data from studies using the most common assessment instrument were meta-analyzed. RESULTS: We identified 27 studies (2880 patients) among 27,334 citations. The Hospital Anxiety and Depression Scale-Anxiety (HADS-A) subscale was the most common instrument (81% of studies)...
November 2016: General Hospital Psychiatry
https://www.readbyqxmd.com/read/27782830/patient-outcomes-after-critical-illness-a-systematic-review-of-qualitative-studies-following-hospital-discharge
#8
Mohamed D Hashem, Aparna Nallagangula, Swaroopa Nalamalapu, Krishidhar Nunna, Utkarsh Nausran, Karen A Robinson, Victor D Dinglas, Dale M Needham, Michelle N Eakin
BACKGROUND: There is growing interest in patient outcomes following critical illness, with an increasing number and different types of studies conducted, and a need for synthesis of existing findings to help inform the field. For this purpose we conducted a systematic review of qualitative studies evaluating patient outcomes after hospital discharge for survivors of critical illness. METHODS: We searched the PubMed, EMBASE, CINAHL, PsycINFO, and CENTRAL databases from inception to June 2015...
October 26, 2016: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/27756148/clinical-effects-of-unintentional-pediatric-buprenorphine-exposures-experience-at-a-single-tertiary-care-center
#9
Michael S Toce, Michele M Burns, Katherine A O'Donnell
CONTEXT: Exploratory buprenorphine ingestions in young children have been associated with clinically significant toxicity. However, detailed data on the clinical presentation and management of these patients are lacking. In an attempt to obtain more comprehensive data, we sought to examine a single center cohort of patients with report of buprenorphine exposure and provide descriptive analysis of rates of respiratory depression, time to respiratory depression, interventions, disposition, and outcomes...
October 19, 2016: Clinical Toxicology
https://www.readbyqxmd.com/read/27752785/dexmedetomidine-for-refractory-adrenergic-crisis-in-familial-dysautonomia
#10
Ryan C Dillon, Jose-Alberto Palma, Christy L Spalink, Diana Altshuler, Lucy Norcliffe-Kaufmann, David Fridman, John Papadopoulos, Horacio Kaufmann
OBJECTIVE: Adrenergic crises are a cardinal feature of familial dysautonomia (FD). Traditionally, adrenergic crises have been treated with the sympatholytic agent clonidine or with benzodiazepines, which can cause excessive sedation and respiratory depression. Dexmedetomidine is a centrally-acting α 2-adrenergic agonist with greater selectivity and shorter half-life than clonidine. We evaluated the preliminary effectiveness and safety of intravenous dexmedetomidine in the treatment of refractory adrenergic crisis in patients with FD...
October 17, 2016: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/27695894/a-recovery-program-to-improve-quality-of-life-sense-of-coherence-and-psychological-health-in-icu-survivors-a-multicenter-randomized-controlled-trial-the-rapit-study
#11
Janet F Jensen, Ingrid Egerod, Morten H Bestle, Doris F Christensen, Ask Elklit, Randi L Hansen, Heidi Knudsen, Louise B Grode, Dorthe Overgaard
PURPOSE: The aim of this randomized controlled trial (RCT) was to test the effectiveness of a post-ICU recovery program compared to standard care during the first year after ICU discharge. METHODS: A pragmatic, non-blinded, multicenter, parallel-group RCT was conducted between December 2012 and December 2015, at ten intensive care units (ICUs) in Denmark. We randomly assigned 386 adult patients (≥18 years) after receiving mechanical ventilation (≥48 h) to standard care (SC) plus a nurse-led intensive care recovery program or standard care alone after ICU discharge (190 intervention, 196 SC)...
November 2016: Intensive Care Medicine
https://www.readbyqxmd.com/read/27690068/a-brief-cognitive-behavioral-psycho-education-b-cbe-program-for-managing-stress-and-anxiety-of-main-family-caregivers-of-patients-in-the-intensive-care-unit
#12
Vico Chung Lim Chiang, Wai Tong Chien, Ho Ting Wong, Rainbow Lai Ping Lee, Juana Ha, Sharron Shuk Kam Leung, Daniel Fu Keung Wong
Having a loved one in the intensive care unit (ICU) is a stressful event, which may cause a high level of anxiety to the family members. This could threaten their wellbeing and ability to support the patients in, or after discharge from, the ICU. To investigate the outcomes of a brief cognitive-behavioral psycho-education program (B-CBE) to manage stress and anxiety of the main family caregivers (MFCs), a pragmatic quasi-experimental study involving 45 participants (treatment group: 24; control group: 21) was conducted in an ICU...
2016: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/27683673/parent-child-perceptions-of-child-health-after-sibling-death
#13
Rosa M Roche, Dorothy Brooten, JoAnne M Youngblut
BACKGROUND: Understanding children's health after a sibling's death and what factors may affect it is important for treatment and clinical care. This study compared children's and their parents' perceptions of children's health and identified relationships of children's age, gender, race/ethnicity, anxiety, and depression and sibling's cause of death to these perceptions at 2 and 4 months after sibling death. METHODS: 64 children and 48 parents rated the child's health "now" and "now vs before" the sibling's death in an ICU or ER or at home shortly after withdrawal of life-prolonging technology...
2016: International Journal of Nursing & Clinical Practices
https://www.readbyqxmd.com/read/27671976/burnout-syndrome-in-critical-care-team-members-a-monocentric-cross-sectional-survey
#14
Stéphanie Malaquin, Yazine Mahjoub, Arianna Musi, Elie Zogheib, Alexis Salomon, Mathieu Guilbart, Hervé Dupont
INTRODUCTION: There has been a growing interest in evaluating the occurrence of burnout syndrome (BOS) among intensive care units (ICU) team over recent years. The aims of this study were to determine the prevalence of BOS among staff working in the Amiens University Hospital and to assess associated factors. PATIENTS AND METHODS: Prospective observational study based on self-administered questionnaires filled in by physicians and non-physicians working in 3 ICUs...
September 23, 2016: Anaesthesia, Critical Care & Pain Medicine
https://www.readbyqxmd.com/read/27648417/a-comparative-study-of-the-efficacy-and-psychological-states-between-patients-with-senile-ischemic-heart-failure-undergone-icu-and-conventional-therapies
#15
Changli DU
BACKGROUND: Our aim was to forward an effective therapeutic approach by comparing efficacy and psychological states between patients with senile ischemic heart failure undergone ICU and conventional therapies. METHODS: We selected 64 patients from Hospital of Traditional Chinese Medicine of Rizhao (Shandong, China) between June 2013 and June 2014. The patients had ischemic heart disease, and were monitored for one-year time span. They were randomly divided into the experiment and control group, each of which of 32 cases...
June 2016: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/27631259/opioid-free-general-anesthesia-in-patient-with-steinert-syndrome-myotonic-dystrophy-case-report
#16
Tomasz Gaszynski
INTRODUCTION: We report on the anesthetic management using opioid-free method of a patient with Steinert syndrome (myotonic dystrophy, MD), autosomal dominant dystrophy which is characterized by consistent contracture of muscle following stimulation. A myotonic crisis can be induced by numerous factors including hypothermia, shivering, and mechanical or electrical stimulation. In patients with MD, hypersensitivity to anesthetic drugs, especially muscle relaxants and opioids, may complicate postoperative management...
September 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27618935/effect-of-a-musical-intervention-on-tolerance-and-efficacy-of-non-invasive-ventilation-in-the-icu-study-protocol-for-a-randomized-controlled-trial-musique-pour-l-insuffisance-respiratoire-aigue-mus-ira
#17
Jonathan Messika, David Hajage, Nataly Panneckoucke, Serge Villard, Yolaine Martin, Emilie Renard, Annie Blivet, Jean Reignier, Natacha Maquigneau, Annabelle Stoclin, Christelle Puechberty, Stéphane Guétin, Aline Dechanet, Amandine Fauquembergue, Stéphane Gaudry, Didier Dreyfuss, Jean-Damien Ricard
BACKGROUND: Non-invasive ventilation (NIV) tolerance is a key factor of NIV success. Hence, numerous sedative pharmacological or non-pharmacological strategies have been assessed to improve NIV tolerance. Music therapy in various health care settings has shown beneficial effects. In invasively ventilated critical care patients, encouraging results of music therapy on physiological parameters, anxiety, and agitation have been reported. We hypothesize that a musical intervention improves NIV tolerance in comparison to conventional care...
2016: Trials
https://www.readbyqxmd.com/read/27618269/long-term-outcomes-after-icu-admission-triage-in-octogenarians
#18
Finn H Andersen, Hans Flaatten, Pål Klepstad, Turid Follestad, Kristian Strand, Andreas J Krüger, Michael Hahn, Christian Buskop, Anne-Karin Rime, Reidar Kvåle
OBJECTIVE: To describe ICU admission triage and outcomes in octogenarians. DESIGN: Multicenter prospective observational study. SETTING: Three nonuniversity hospitals and three university hospitals in Norway. PATIENTS: Patients 80 years old or older who were referred for ICU admission from November 2013 to October 2014. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Of the 355 included patients, 105 (29...
September 9, 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27610588/clinical-significance-of-palliative-care-assessment-in-patients-referred-for-urgent-intensive-care-unit-admission-a-cohort-study
#19
Joao Gabriel Rosa Ramos, Mario Diego Teles Correa, Ricardo Tavares de Carvalho, Daryl Jones, Daniel Neves Forte
PURPOSE: To evaluate clinical characteristics of patients with palliative care (PC) and urgent intensive care unit (ICU) referrals in the same hospital admission. METHODS: All urgent ICU referrals at an academic, tertiary hospital, and the co-occurrence and timing of PC assessment were retrieved from a prospectively collected database. RESULTS: From May 2014 to May 2015, 2476 patients were analyzed and 179 (7%) had co-occurrence of PC assessment and urgent ICU referral in the same hospital admission...
August 21, 2016: Journal of Critical Care
https://www.readbyqxmd.com/read/27546765/psychosocial-resiliency-is-associated-with-lower-emotional-distress-among-dyads-of-patients-and-their-informal-caregivers-in-the-neuroscience-intensive-care-unit
#20
Kelly M Shaffer, Eric Riklin, Jamie M Jacobs, Jonathan Rosand, Ana-Maria Vranceanu
PURPOSE: The purpose of the study is to examine the associations of patients' and their informal caregivers' psychosocial resiliency factors with their own and their partners' emotion domains (distress, anxiety, depression, and anger) after admission to the neuroscience intensive care unit (Neuro-ICU). MATERIALS AND METHODS: Eighty-three dyads of patients (total n = 87) and their informal caregivers (total n = 99) participated in this observational, cross-sectional study by self-reporting demographics and measures of resiliency factors (mindfulness [Cognitive and Affective Mindfulness Scale Revised], coping [Measure of Coping Status-A], intimate bond [Intimate Bond Measure], self-efficacy [patients: General Self-Efficacy Scale; caregivers: Revised Caregiver Self-Efficacy Scale]) and emotion domains (Emotion Thermometers) within 2 weeks of Neuro-ICU admission...
July 16, 2016: Journal of Critical Care
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