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https://www.readbyqxmd.com/read/29350646/radiofrequency-ablation-of-osteoid-osteoma
#1
Massimo De Filippo, Umberto Russo, Vito Roberto Papapietro, Francesco Ceccarelli, Francesco Pogliacomi, Enrico Vaienti, Claudia Piccolo, Raffaella Capasso, Assunta Sica, Fabrizio Cioce, Mattia Carbone, Federico Bruno, Carlo Masciocchi, Vittorio Miele
Osteoid osteoma is a benign bone neoplasm with a reported incidence of 2-3% among all bone primary tumors. Although it is a small and benign lesion, it is often cause of patient complaint and discomfort. It is generally characterized by a long lasting, unremitting pain that typically exacerbates at night, often leading to sleep deprivation and functional limitation of the skeletal segment involved, with a significant reduction of patient daily life activities and consequent worsening of the overall quality of life...
January 19, 2018: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29350012/-application-of-debridement-and-bone-autografting-combined-with-proximal-femoral-anatomical-plates-for-benign-tumor-in-proximal-femur
#2
Ye Tian, Long-Gang Chen, Bin Shi, Nan Zhang, Qin Fu
OBJECTIVE: To explore the clinical effects of debridement and bone autografting combined with proximal femoral anatomical plate in treating benign tumor in proximal femur. METHODS: From January 2010 to October 2014, 30 patients with benign tumor in proximal femur were treated with debridement, autogenic ilium, autogenic ilium and allogeneic bone implant, and anatomic plate fixation. Among them, there were 13 males and 17 females aged from 12 to 68 years old with an average of 42 years old...
February 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29349054/post-traumatic-peripheral-giant-osteoma-in-the-frontal-bone
#3
Seong Hwan Kim, Dong Seob Lim, Do Hun Lee, Kyung Pil Kim, Jae Ha Hwang, Kwang Seog Kim, Sam Yong Lee
Osteomas are benign, slow-growing tumors that most frequently occur in the craniomaxillofacial region. These tumors are mostly asymptomatic and are generally found incidentally. A giant osteoma is generally considered to be greater than 30 mm in diameter or 110 g in weight. A 35-year-old female presented to us with complaints of a firm mass that showed continuous growth on the forehead following trauma. A hairline incision was made to expose the osteoma. Biopsy of the tumor confirmed a osteoma. There were no complications after surgery...
December 2017: Archives of Craniofacial Surgery
https://www.readbyqxmd.com/read/29333027/ewing-s-sarcoma-of-the-calcaneum
#4
P Ajmal Sherif, A Santa
Ewing's sarcoma of the calcaneum is rare. Radiological features of this tumor can be misinterpreted as other benign bone tumors due to its rarity. The overall prognosis of Ewing's sarcoma of calcaneum is inferior compared to other sites of this tumor. Hence, these tumors should have extensive radiological evaluation and histological confirmation as misdiagnosis and treatment delays will have detrimental outcomes.
October 2017: Indian Journal of Medical and Paediatric Oncology
https://www.readbyqxmd.com/read/29324473/chondromyxoid-fibroma-arising-in-craniofacial-sites-a-clinicopathologic-analysis-of-25-cases
#5
David M Meredith, Christopher D M Fletcher, Vickie Y Jo
Chondromyxoid fibroma (CMF) is a rare benign tumor, usually arising in the metaphysis of long bones in young adults. Occurrence in craniofacial bones presents a particular diagnostic challenge given its unusual location and resemblance to malignant mimics. We describe the clinicopathologic features of 25 cases of craniofacial CMF identified between 1999 and 2017. Patients were 14 men and 11 women, with median age of 44 years (range, 5 to 83 y). Sites of involvement were sphenoid (7), ethmoid (5), maxilla (3), occipital (2), nasal septum (2), palatine (2), temporal (2), orbit (1), and undisclosed skull (1)...
January 10, 2018: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29320333/prostate-specific-membrane-antigen-pet-clinical-utility-in-prostate-cancer-normal-patterns-pearls-and-pitfalls
#6
Michael S Hofman, Rodney J Hicks, Tobias Maurer, Matthias Eiber
Prostate-specific membrane antigen (PSMA) is a transmembrane glycoprotein that is overexpressed in prostate cancer. Radiolabeled small molecules that bind with high affinity to its active extracellular center have emerged as a potential new diagnostic standard of reference for prostate cancer, resulting in images with extraordinary tumor-to-background contrast. Currently, gallium 68 (68Ga)-PSMA-11 (or HBED-PSMA) is the most widely used radiotracer for PSMA positron emission tomography (PET)/computed tomography (CT) or PSMA PET/magnetic resonance (MR) imaging...
January 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29311424/jaw-bones-regeneration-using-mesenchymal-stem-cells-a-single-center-experience
#7
Walter Colangeli, Umberto Riccelli, Amerigo Giudice, Ida Barca, Davide Caruso, Daniela Novembre, Claudio Tortosa, Raffaella Cordaro, Maria Giulia Cristofaro
PURPOSE: Mesenchymal stem cells (MSC), which are multipotent stromal cells, are considered to be a promising resource in tissue engineering and tissue regeneration. MSCs have been used to generate new maxillary bone with clinically successful results. The aim of this study was to determine the role of MSC in bone regeneration procedures in patients with benign maxillary lesions. METHODS: A study was conducted on five patients treated for maxillary bone defects resulting from biopsy of benign lesions at the University Hospital of Magna Græcia, Catanzaro, Italy from January 2015 to October 2016...
December 21, 2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/29310397/massive-rare-desmoplastic-fibroma-of-the-ilium-and-ischium-in-a-young-adult-a-case-report
#8
Xin-Nan Ma, Shuai Qiang, Tian-Yi Liu, Mei-Yu Cao, Song-Cen Lv
RATIONALE: Desmoplastic fibroma (DF) is a rare, locally invasive but benign bone tumor. It represents one of the rarest bone diseases, with an incidence of only 0.11% of all primary bone tumors. PATIENT CONCERNS: Herein, a case of massive and unusual DF, with simultaneous involvement of ilium and ischium, is described. A 29-year-old man suffered minor pain in his right hip for 2 years. It worsened after sudden movements, which prevented him from walking normally...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29310392/cavernous-hemangiomas-of-the-temporalis-muscle-with-prominent-formation-of-phleboliths-case-report-and-review-of-the-literature
#9
Bin Cui, Dan-Hui Wang, Guan-Jun Wang, Peng Cheng, Feng Zhang, Xiao-Bing Duan, Zhong-Fu Zhao
RATIONALE: Hemangiomas are benign tumors characterized by an abnormal proliferation of blood vessels, most often occur in the skin and subcutaneous tissue, intramuscular hemangioma, a distinctive type of hemangioma within the skeletal muscle, account for <1% of all hemangiomas, temporalis muscle is a very uncommon site, cavernous hemangioma of the temporalis muscle with prominent formation of phleboliths is rare reported. PATIENT CONCERNS: A 62-year-old man presented with a slowly increased mass in his right temporal fossa...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29306659/breast-osteoblast-like-cells-a-reliable-early-marker-for-bone-metastases-from-breast-cancer
#10
Manuel Scimeca, Chiara Antonacci, Nicola Toschi, Elena Giannini, Rita Bonfiglio, Claudio Oreste Buonomo, Chiara Adriana Pistolese, Umberto Tarantino, Elena Bonanno
BACKGROUND: The development of bone metastasis from breast cancer results from a functional interaction between tumor cells and osteoclasts or osteoblasts. The main aim of this study was therefore to test the hypothesis that the appearance of breast osteoblast-like cells (BOLCs) in primary mammary lesions is a precursor (and hence an early predictor) of the formation of breast cancer metastases to bone. PATIENTS AND METHODS: In this study, we collected 64 breast infiltrating carcinomas, 50 breast benignant lesions, and 10 biopsies of bone metastasis selected from patients with infiltrated carcinoma...
December 5, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/29303762/giant-schwannoma-of-the-hard-palate-a-literature-review-and-report-of-an-uncommon-case
#11
Cristinne Andrade Melo, Paulo Almeida-Júnior, Allan Ulisses de Carvalho Melo, Cyntia Ferreira Ribeiro, Cláudio Élcio Siqueira de Lira, Juliana Batista Melo da Fonte, Maria Fátima Batista de Melo, Wilton Mitsunari Takeshita, Ricardo Luiz Cavalcanti de Albuquerque-Júnior
Schwannomas (also known as neurilemomas) are benign tumors that arise from the Schwann cells of the nerve sheath. While they seldom occur in the oral cavity, the tongue is the most common site. Palatal schwannomas are extremely rare. This article reports a case of a large, slowly developing schwannoma that caused bone erosion in the hard palate of an 18-year-old man. The diagnosis was based on histopathologic and immunohistochemical findings. The tumor was completely excised, and no recurrence was observed at a 1-year follow-up...
January 2018: General Dentistry
https://www.readbyqxmd.com/read/29302139/single-stage-surgery-using-calcium-sulfate-pellets-in-association-with-tumor-resection-as-treatment-for-intraosseous-hemangioma-of-the-radius-shaft-in-a-2-year-old-boy
#12
Antonio Andreacchio, Flavia Alberghina, Vanessa Giacometti, Lorenza Marengo, Federico Canavese
Intraosseous hemangiomas are uncommon benign vascular tumors. Here the authors report a case of intraosseous hemangioma of the radial shaft in a 2-year-old boy, surgically treated by tumor mass resection and application of calcium sulfate pellets with no signs of relapse over a 2-year follow-up. Moreover, the lesion healed with new bone formation, and the last plain radiographs suggested homogenous normal trabecular bone density. The radius grew in length and remodeled to an almost normal shape. Clinically, elbow flexion-extension and forearm pronation and supination were within normal limits at the last follow-up visit...
December 2017: Journal of Hand and Microsurgery
https://www.readbyqxmd.com/read/29296223/development-and-validation-of-a-prognostic-index-to-predict-pulmonary-metastasis-of-giant-cell-tumor-of-bone
#13
Bo Wang, Wei Chen, Xianbiao Xie, Jian Tu, Gang Huang, Changye Zou, Junqiang Yin, Lili Wen, Jingnan Shen
Purpose: Giant cell tumor of bone (GCTB) is an intermittent tumor with a low probability of pulmonary metastasis. Our aim was to investigate the risk factors and establish a nomogram predictive model for GCTB pulmonary metastasis. Methods: We retrospectively evaluated GCTB patients at our center from 1991 to 2014. The cohort was randomized into training and validation sets. Univariate and multivariate analyses were used to evaluate the risk factors of pulmonary metastasis...
December 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/29287893/-tumoral-calcinoses-in-a-chronic-hemodialysis-patient-the-role-of-spect-ct-hybrid-imaging
#14
Aboubakr Matrane, Soufiane Hiroual, Mohamed Aziz Bsiss, Safa Bennani Doubli
INTRODUCTION: Tumoral calcinosis is a rare benign disease, defined by the presence of calcified deposits in periarticular tissues. It can be hereditary or secondary at chronic renal failure at the stage of dialysis. This work illustrates the contribution of single-photon emission computed tomography (SPECT/CT) in the diagnosis and management of tumoral calcinoses in a chronic hemodialysis patient, based on a clinical case. CASE REPORT: A 62-year-old patient, chronic hemodialysis since 24 years, presented a mechanical pain shoulders, knees and hips with limitation of joint mobility...
December 26, 2017: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/29287595/dealing-with-chronic-non-bacterial-osteomyelitis-a-practical-approach
#15
REVIEW
Andrea Taddio, Giovanna Ferrara, Antonella Insalaco, Manuela Pardeo, Massimo Gregori, Martina Finetti, Serena Pastore, Alberto Tommasini, Alessandro Ventura, Marco Gattorno
BACKGROUND: Chronic Non-Bacterial Osteomyelitis (CNO) is an inflammatory disorder that primarily affects children. Although underestimated, its incidence is rare. For these reasons, no diagnostic and no therapeutic guidelines exist. The manuscript wants to give some suggestions on how to deal with these patients in the every-day clinical practice. MAIN BODY: CNO is characterized by insidious onset of bone pain with local swelling. Systemic symptoms such as fever, skin involvement and arthritis may be sometimes present...
December 29, 2017: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/29286966/isolated-scapular-metastasis-in-a-patient-with-malignant-struma-ovarii-a-case-report
#16
Juliane Comunello, Fábio Fernando Eloi Pinto, Suely Akiko Nakagawa, Wu Tu Chung, Felipe D'Almeida Costa, Américo Delgado Brilhante
CASE: We report the case of a 38-year-old woman who presented with a lytic bone lesion in the left scapula. A biopsy showed a tumor with the histologic appearance of thyroid tissue. She also was found to have a thyroid nodule and an enlarged ovary, both of which were excised. The thyroid nodule turned out to be a benign colloid nodule, and the ovary contained a monodermal teratoma composed of thyroid tissue (struma ovarii). The lesion in the scapula eventually was proven to be metastatic malignant struma ovarii...
October 2017: JBJS Case Connector
https://www.readbyqxmd.com/read/29286564/denosumab-treatment-in-aneurysmal-bone-cyst-evaluation-of-nine-cases
#17
Nilgun Kurucu, Canan Akyuz, Fatma Bilge Ergen, Bilgehan Yalcin, Kemal Kosemehmetoglu, Mehmet Ayvaz, Ali Varan, Burca Aydin, Tezer Kutluk
BACKGROUND: Aneurysmal bone cyst (ABC) is a benign bone tumor. Curettage and bone grafting is the common treatment. Here, we retrospectively evaluate nine patients treated with denosumab. PROCEDURE: Nine patients with ABC, mostly pelvic and vertebral, treated with denosumab were analyzed retrospectively. A 70 mg/m2 denosumab dose was used weekly in the first month, and then monthly. Clinical and radiological responses to treatment were evaluated. RESULTS: In all patients, clinical symptoms including pain and limping regressed completely within 3 months...
December 29, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29286549/musculoskeletal-complications-following-total-body-irradiation-in-hematopoietic-stem-cell-transplant-patients
#18
REVIEW
Taylor J Jackson, Sogol Mostoufi-Moab, Christine Hill-Kayser, Naomi J Balamuth, Alexandre Arkader
Total body irradiation (TBI) is commonly used in conditioning regimens for allogeneic hematopoietic stem cell transplantation (HSCT) to treat benign and malignant disease. Though life-saving, these therapies place patients at risk for important side effects, including musculoskeletal complications such as short stature, osteonecrosis, slipped capital femoral epiphysis, and the development of benign and malignant bone tumors. With an increasing number of HSCT survivors, there is a growing need for awareness of the musculoskeletal complications of HSCT and TBI...
December 29, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29283937/piezosurgery-for-treatment-of-large-recurrent-mandibular-osteoma
#19
Josué Hernando, Antonio Aguilar-Salvatierra, Ignacio Osoitz Leizaola-Cardesa, Pedro Martínez Seijas, Pablo Aguirre-Echebarria, Javier Martín, Gerardo Gómez-Moreno
BACKGROUND: Osteomas are infrequent benign bone tumors of uncertain etiology. They are usually situated at extremities and their occurrence in the jaws is relatively rare. There are 3 types of osteoma: central, peripheral, and extraskeletal. Preoperative presumptive diagnosis is performed by means of radiography using orthopantomographs, computerized tomographs, or cone beam scans. Treatment is surgical and consists of careful exeresis and curettage of the adjacent tissue. In recent years, piezoelectric surgery has been used to treat bone pathologies in the maxillofacial area, orthopedic surgery, and neurosurgery...
December 27, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29281780/hepatocellular-carcinoma-arising-in-a-huge-hepatocellular-adenoma-with-bone-marrow-metaplasia
#20
Hyo Jeong Kang, Hui Jeong Jeong, So-Woon Kim, Eunsil Yu, Young-Joo Lee, So Yeon Kim, Jihun Kim
Hepatocellular adenoma (HCA) is the most common type of benign liver tumor, and its major complication is malignant transformation to hepatocellular carcinoma (HCC). Here, we report a case of HCC arising in HCA with bone marrow metaplasia in a 24-year-old Korean woman who presented with abdominal discomfort. A huge liver mass was found on abdominal ultrasonography. She underwent surgical hepatic resection, and the resected specimen was entirely involved by a 20 cm sized tumor. Histological review revealed a well differentiated HCC arising from inflammatory HCA with β-catenin nuclear positivity and bone marrow metaplasia that contained hematopoietic cells...
December 27, 2017: Journal of Pathology and Translational Medicine
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