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benign bone tumor

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https://www.readbyqxmd.com/read/28526004/hybrid-peripheral-nerve-sheath-tumors-report-of-five-cases-and-detailed-review-of-literature
#1
Nasir Ud Din, Zubair Ahmad, Jamshid Abdul-Ghafar, Rashida Ahmed
BACKGROUND: Hybrid peripheral nerve sheath tumors (PNSTs) have been recognized recently and were first included in the 4th edition of World Health Organization (WHO) Classification of Tumors of Soft tissue and Bone, published in 2013. These tumors show combined features of more than one type of conventional benign peripheral nerve sheath tumors. The most common combinations are those of schwannoma/perineurioma followed by combinations of neurofibroma/schwannoma and neurofibroma/perineurioma...
May 19, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28508997/fibromyxoma-of-the-jaw-case-report-and-review-of-the-literature
#2
Thabet Alhousami, Amarpreet Sabharwal, Shivane Gupta, Alfredo Aguirre, Etern Park, Jill M Kramer
We report a case of fibromyxoma of the mandible, a rare benign odontogenic tumor. Our patient presented in the first trimester of pregnancy with a large mass in the right body of the mandible exhibiting displacement of teeth and destruction of an extensive area of the mandibular bone. The mass was biopsied and diagnosed as a fibromyxoma. The large size of the tumor dictated a wide mandibular resection. We will review the clinical, radiographic, and histologic features of fibromyxoma and discuss its differential diagnoses...
May 16, 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/28507976/painful-pseudowinging-and-snapping-of-scapula-due-to-subscapular-osteochondroma-a-case-report
#3
Raja Rameez, Mehmood Ul-Hassan, Hilal A Kotwal, Khursheed A H Kangoo, Asif Nazir
INTRODUCTION: Osteochondroma or exostosis is most common benign bone tumors. They are usually seen in the metaphyses of long bones with more than 35% of cases affecting the bone around the knee and are seldom found in flat bones like scapula. When present in scapula, they may cause abnormal scapulothoracic movements leading to pain, snapping, and pseudowinging of scapula. CASE REPORT: We describe a novel case of osteochondroma arising on the ventral aspect of right scapula in a 16-year-old otherwise healthy female patient causing snapping and pseudowinging of scapula and occasional pain in affected area...
November 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28507956/an-unusual-case-of-giant-cell-tumor-of-first-metatarsal-a-rare-case-report-and-review-of-literature
#4
Kumar Prashant, Tulsi Das Bhattacharyya, Herman Frank, Prema Ram
INTRODUCTION: Giant cell tumor (GCT) or osteoclastoma is an osteolytic, mostly benign but locally aggressive tumor occurring in young adults at the epiphysis. Area of predilection is mainly long bones (85-90%). 4% of GCT are also found in iliac bone, spine and only 2% in hand (of which GCT phalanges are more common than metacarpal). GCT of metatarsal is a very rare occurrence with very few cases being reported so far. We report a case of GCT 1(st) metatarsal in a 40-year-old male which is a very rare entity...
November 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28507546/extracellular-signal-regulated-kinase-signaling-in-cd4-expressing-cells-inhibits-osteochondromas
#5
Marie Wehenkel, Maripat Corr, Clifford S Guy, Benjamin A Edwards, Ashley H Castellaw, Christopher Calabrese, Gilles Pagès, Jacques Pouysségur, Peter Vogel, Maureen A McGargill
Defects in cartilage homeostasis can give rise to various skeletal disorders including osteochondromas. Osteochondromas are benign bone tumors caused by excess accumulation of chondrocytes, the main cell type of cartilage. The extracellular signal-regulated kinase (ERK) pathway is a major signaling node that functions within chondrocytes to regulate their growth and differentiation. However, it is not known whether the ERK pathway in other cell types regulates cartilage homeostasis. We show here that mice with a germline deficiency of Erk1 and a conditional deletion of Erk2 in cells that express CD4, or expressed CD4 at one point in development, unexpectedly developed bone deformities...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28506169/painful-snapping-of-thumb-caused-by-osteochondroma-of-trapezium
#6
Navapong Anantavorasakul, Chairoj Uerpairojkit, Somsak Leechavengvongs
Osteochondroma is the most common benign bone tumor. Lesions occurring at the carpal bones are extremely rare. There are very few cases of osteochondroma at the trapezium had been reported in the English literature. We reported a 47-year-old patient with an osteochondroma of the left trapezium presented with painful snapping of abductor pollicis longus tendon.
June 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/28506022/breast-osteoblastoma-and-recurrence-after-resection-demonstration-by-color-doppler-ultrasound
#7
Xia Li, Hua Xin, Shifeng Yang, Miaoqing Zhao, Ximing Wang, Nan Zhang
Osteoblastoma is a rare benign primary bone tumor, which occurs in any part of the skeleton. Extraskeletal osteoblastoma is rather rare. We presented an extremely rare case of extraskeletal osteoblastoma located in the breast. The tumor recurred 7 months later after resection and transformed to aggressive osteoblastoma. The histopathological features, ultrasonic manifestations and ultrasonic differential diagnoses of the primary and recurrent tumors were discussed. The recommended treatment of the tumor is surgical excision...
May 6, 2017: Journal of X-ray Science and Technology
https://www.readbyqxmd.com/read/28505000/h3f3a-histone-3-3-g34w-immunohistochemistry-a-reliable-marker-defining-benign-and-malignant-giant-cell-tumor-of-bone
#8
Fernanda Amary, Fitim Berisha, Hongtao Ye, Manu Gupta, Alice Gutteridge, Daniel Baumhoer, Rebecca Gibbons, Roberto Tirabosco, Paul O'Donnell, Adrienne M Flanagan
Giant cell tumor of bone (GCTB) is a locally aggressive subarticular tumor. Having recently reported that H3.3 G34W mutations are characteristic of this tumor type, we have now investigated the sensitivity and specificity of the anti-histone H3.3 G34W rabbit monoclonal antibody in a wide variety of tumors including histologic mimics of GCTB to assess its value as a diagnostic marker. We also determined the incidence of H3.3 G34 mutations in primary malignant bone tumors as assessed by genotype and H3.3 G34W immunostaining...
May 12, 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28502566/lateral-skull-base-chondroblastoma-resected-with-facial-nerve-posterior-transposition
#9
J Adnot, O Langlois, E Tollard, M Crahes, I Auquit-Auckbur, J-P Marie
INTRODUCTION: Chondroblastoma is a rare tumor that can involve the temporal bone. Because it is a benign tumor, functional surgery must be proposed. We report a case of a patient with a massive chondroblastoma operated on with preservation of the facial nerve, and description of the surgical technique. CASE PRESENTATION: A 37-year-old man presented with a 9-month history of a growing left pre-auricular mass and hearing loss. Neuroimaging showed an osteolytic mass invading the temporal bone and temporomandibular joint...
May 11, 2017: Neuro-Chirurgie
https://www.readbyqxmd.com/read/28496119/clinical-experience-with-the-artificial-bone-graft-substitute-calcibon-used-following-curettage-of-benign-and-low-grade-malignant-bone-tumors
#10
Joerg Friesenbichler, Werner Maurer-Ertl, Marko Bergovec, Lukas A Holzer, Kathrin Ogris, Lukas Leitner, Andreas Leithner
Artificial bone graft substitutes, such as Calcibon, are becoming increasingly interesting as they do not cause donor site morbidity which is an advantage compared to autologous bone grafts. The aim of this study was to evaluate the efficacy and potential complications associated with the use of Calcibon. Twenty-seven patients with benign and low-grade malignant bone tumors were treated with curettage and refilling of the bony cavity. Based on the radiological classification system of Neer, these lesions only comprised Grade I lesions, describing cysts that only require curettage and filling, but no additional treatment...
May 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28493806/pediatric-benign-bone-tumors-what-does-the-radiologist-need-to-know-pediatric-imaging
#11
Jignesh N Shah, Harris L Cohen, Asim F Choudhri, Saurabh Gupta, Stephen F Miller
No abstract text is available yet for this article.
May 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28485333/tumors-and-tumor-like-conditions-of-the-nasal-cavity-paranasal-sinuses-and-nasopharynx-a-study-of-206-cases
#12
R N Satarkar, S Srikanth
INTRODUCTION: The nasal cavity, paranasal sinuses, and nasopharynx though in continuity form a complex system of upper respiratory tract; this region is endowed with a variety of elements such as epithelial, glandular, lymphoid, cartilage, and bone and is also exposed to a variety of infections, tumor-like and true neoplastic conditions. AIMS AND OBJECTIVES: To find out the frequency of various tumors and tumor-like conditions of the nasal cavity, paranasal sinuses, and nasopharynx...
October 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28480084/concomitant-central-giant-cell-granuloma-and-aneurysmal-bone-cyst-in-a-young-child
#13
Deepika Pai, Abhay Taranath Kamath, Adarsh Kudva, Monica Monica Charlotte Solomon, Saurabh Kumar, Prem Sasikumar
Although Central Giant Cell Granuloma (CGCG) is a benign tumor of the jaw and aneurysmal bone cyst seen in children, its aggressive behavior causes extensive loss of hard tissue requiring wide excision and extensive rehabilitation. We report a rare case of concomitant CGCG and aneurysmal bone cyst in a two-year-old male child, involving the coronoid and condylar process. Young age, large tumor, its aggressive nature, and future growth of orofacial region pose a significant challenge in the management of such conditions...
2017: Case Reports in Dentistry
https://www.readbyqxmd.com/read/28477224/bone-tumors-of-the-pediatric-foot-imaging-appearances
#14
Pablo Caro-Domínguez, Oscar M Navarro
Tumors of the foot are rare in children. This review illustrates radiographic, CT and MR imaging findings of foot bone tumors in children based on all cases presented in a tertiary pediatric hospital during the 15-year period of 1999-2014. This search revealed 155 tumors of the foot, 72 of the bones and 83 of the soft tissues. Osteochondroma, bone cyst and fibrous dysplasia were the most frequent benign bone lesions. Ewing sarcoma was the most common malignant osseous tumor. Some tumors showed higher prevalence in certain age ranges and others showed predilection for specific bones...
May 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28476174/a-patient-with-a-history-of-breast-cancer-and-multiple-bone-lesions-a-case-report
#15
Marie-Angela Schnyder, Paul Stolzmann, Gerhard Frank Huber, Christoph Schmid
BACKGROUND: Long-term severe hyperparathyroidism leads to thinning of cortical bone and cystic bone defects referred to as osteitis fibrosa cystica. Cysts filled with hemosiderin deposits may appear colored as "brown tumors." Osteitis fibrosa cystica and brown tumors are occasionally visualized as multiple, potentially corticalis-disrupting bone lesions mimicking metastases by bone scintigraphy or (18)F-fluorodeoxyglucose positron emission tomography. CASE PRESENTATION: We report a case of a 72-year-old white woman who presented with malaise, weight loss, and hypercalcemia...
May 6, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28476024/dual-time-point-18f-fdg-pet-ct-imaging-with-multiple-metabolic-parameters-in-the-differential-diagnosis-of-malignancy-suspected-bone-joint-lesions
#16
Chen-Tian Shen, Zhong-Ling Qiu, Zhen-Kui Sun, Wei-Jun Wei, Hong-Jun Song, Xin-Yun Zhang, Quan-Yong Luo
The purpose of this study was to evaluate the diagnostic potential of dual time-point 18F-FDG PET/CT imaging with multiple metabolic parameters in malignancy-suspected bone/joint lesions. Fifty seven consecutive patients were recruited. PET parameters including SUVmax, SUVmean, metabolic tumor volume (MTV), total lesional glycolysis (TLG) and retention indexes (RIs) were obtained. Thirty five malignant and 22 benign lesions were confirmed by pathology. In all, 48 receiver operating characteristic (ROC) curves were derived...
April 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/28469320/a-rare-tumor-of-salivary-gland-diagnostic-dilemma-on-fine-needle-aspiration-cytology
#17
Charu Agarwal, Manju Kaushal, Minakshi Bhardwaj
Salivary gland cytopathology is a diagnostically challenging area with overlapping cytomorphological features between benign, malignant, and metastatic tumors. We report the case of 45-year-old male who presented with two swellings in right retroauricular and infraauricular region along with a palpable single right cervical lymph node. On ultrasonography of the neck, a possibility of malignant lesion was given. Contrast enhanced computed tomography of the head showed a large well-defined space occupying lesion in right temporooccipital region eroding the skull bone with both extra and intracranial extension...
April 2017: Journal of Cytology
https://www.readbyqxmd.com/read/28468174/the-strategy-of-delayed-reconstruction-of-the-mandible-in-war-injuries
#18
Firas Taha Ahmed, Marwa Turkey Aljeuary
The most common causes of mandibular defects are ablative surgery of benign or malignant tumors, severe trauma, inflammatory diseases, and osteoradionecrosis. War injuries are another cause for mandibular defect. Reconstruction of the mandible is considered a challenge to the maxillofacial surgeon due to the accompanying functional and cosmetic importance. The object of this article was to show the role of nonvascularized bone graft in the reconstruction of segmental defect of the mandible resulted from projectiles and its snags...
May 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28468168/aggressive-osteoblastoma-in-the-maxilla-unusual-lesion-in-the-craniofacial-skeleton
#19
Fued Samir Salmen, Marina Reis Oliveira, Cláudia Maria Navarro, Rogério Aparecido Dedivitis, Valfrido Antonio Pereira Filho, Mario Francisco Real Gabrielli
Osteoblastomas are benign bone tumors, which are unusual in the craniofacial skeleton, being most often observed in the axial skeleton and long bones. The most common site in the maxillofacial region is the mandible and the involvement of the maxilla and paranasal sinuses is extremely rare. Although it is a benign lesion, the aggressive variant raises concerns due to its huge local destructive potential and tendency to relapse. In this clinical case, an aggressive osteoblastoma is described in a 7-year-old patient...
May 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28466103/air-blocking-ablation-of-osteoid-osteoma-a-technical-note
#20
Gokhan Kuyumcu, Evan Gregory Mason, Hakan Ilaslan
Osteoid osteoma accounts for approximately 10-12% of all benign bone tumors. Surgery was the treatment of choice for osteoid osteomas until percutaneous radiofrequency ablation (RFA) was introduced in 1992. Although RFA is generally considered curative in the treatment of osteoid osteoma, disease recurrence after ablation has been reported. We report a case in which RFA was delayed by the presence air surrounding the ablation probe. In this case, ablation could only be performed after the probe was removed and saline was injected through the introducer needle to displace the air...
July 2017: Skeletal Radiology
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