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Embryo transfer Ectopic pregnancy

Shu-Xian Feng, Xue-Lan Li, Xing-Yu Zhou, Yu-Dong Liu, Ping-Ping Guo, De-Sheng Ye, Xin Chen, Shi-Ling Chen
OBJECTIVE: To analyze the incidence, management, and outcomes of monozygotic twin (MZT) pregnancy conceived by assisted reproductive techniques (ART). METHODS: A retrospective analysis was performed of clinical pregnancies after in vitro fertilization and embryo transfer (IVF-ET) and introcytoplasmic sperm injection and embryo transfer (ICSI-ET) from January, 2010 to June 2015 at our center. We investigated the incidence, managements and outcomes of 94 MZT pregnancies...
November 20, 2016: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
Nivin Samara, Yaakov Bentov
BACKGROUND: Ovarian pregnancy is a rare and challenging clinical phenomenon. Recent studies have identified assisted reproductive treatments and infertility as risk factors. However, neither a definite mechanism nor clear risk factors were identified and therefore prevention strategies are yet unavailable. CLINICAL CASE: In this article, we present a case of ovarian pregnancy occurring following in vitro fertilization treatment and a fresh embryo transfer. The couple was diagnosed with unexplained infertility and no identifiable risk factors for extrauterine pregnancy...
2016: Clinical Medicine Insights. Reproductive Health
T Tatsumi, S C Jwa, A Kuwahara, M Irahara, T Kubota, H Saito
STUDY QUESTION: Does letrozole use increase the risk of major congenital anomalies and adverse pregnancy and neonatal outcomes in fresh, single-embryo transfer? SUMMARY ANSWER: Letrozole significantly decreases the risk of miscarriage and does not increase the risk of major congenital anomalies or adverse pregnancy or neonatal outcomes compared with natural cycles in patients undergoing ART. WHAT IS KNOWN ALREADY: Letrozole is the most commonly used aromatase inhibitor for mild ovarian stimulation in ART...
November 7, 2016: Human Reproduction
Nicole Yoder, Reshef Tal, J Ryan Martin
BACKGROUND: Ectopic pregnancy is the leading cause of maternal morbidity and mortality during the first trimester and the incidence increases dramatically with assisted-reproductive technology (ART), occurring in approximately 1.5-2.1 % of patients undergoing in-vitro fertilization (IVF). Abdominal ectopic pregnancy is a rare yet clinically significant form of ectopic pregnancy due to potentially high maternal morbidity. While risk factors for ectopic pregnancy after IVF have been studied, very little is known about risk factors specific for abdominal ectopic pregnancy...
October 19, 2016: Reproductive Biology and Endocrinology: RB&E
V Muller, M Makhmadalieva, I Kogan, I Fedorova, E Lesik, E Komarova, L Dzhemlikhanova, D Niauri, A Gzgzyan, E Ailamazyan
BACKGROUND: Ectopic pregnancy (EP) has been reported to occur in 1.4-5.4% of all clinical pregnancies resulting from in vitro fertilization (IVF) and embryo transfer (ET). Data on factors associated with abnormal embryo implantation following assisted conception are limited. MATERIALS AND METHODS: A systematic review and meta-analysis was performed to determine whether there is an association between the day (cleavage-stage, D3, versus blastocyst, D5) or the type (fresh versus frozen/thawed) of ET and EP rate...
October 2016: Gynecological Endocrinology
Qing-Zhen Xie, Wang-Ming Xu, Qian-Rong Qi, Zeng-Li Luo, Lan Dong
Genital tract infections with ureaplasma urealyticum (UU) and chlamydia trachomatis (CT) are the most frequent sexually-transmitted disease worldwide. UU and CT infections are considered to be the leading cause for infertility and adverse pregnancy outcomes. However, little is known about the specific effect of cervical UU and CT infections on the etiology of female infertility, as well as the pregnancy outcomes of the patients undergoing in vitro fertilization/intracytoplasmic sperm injection-embryo transfer (IVF/ICSI-ET)...
October 2016: Journal of Huazhong University of Science and Technology. Medical Sciences
Xinqi Zhong, Jianqiao Liu, Qiliang Cui, Shaozhen Liang, Yuanqing Lin, Haiying Liu, Qiyi Zeng
Assisted reproductive technologies (ART) are widely used to treat infertility. Emerging evidence suggested that ART was associated with perinatal or neonatal problems, however, little is known about the ART related risk factors. Here using 21136 ART cases, we determined the impacts of parental physiological conditions in the ART mediated pregnancy outcomes. In addition, we further evaluated the effects of three different ART methods (frozen-thawed embryo transfer [FET], in vitro fertilization [IVF] and intracytoplasmic sperm injection [ICSI]) in the pregnancy and birth outcomes in ART mediated pregnancy...
October 10, 2016: Oncotarget
N Navali, A Gassemzadeh, L Farzadi, S Abdollahi, M Nouri, K Hamdi, F Mallah, F Jalilvand
STUDY QUESTION: Does the intrauterine administration of hCG immediately after oocyte retrieval in antagonist cycles with ICSI and fresh embryo transfer (ET) influence the implantation rate or chemical and clinical pregnancy rates? SUMMARY ANSWER: The intrauterine administration of hCG after oocyte retrieval increases the implantation rate and chemical and clinical pregnancy rates. WHAT IS KNOWN ALREADY: Over half of IVF/ICSI cycles fail due to implantation failure...
November 2016: Human Reproduction
Ningyuan Zhang, Hua Chen, Zhipeng Xu, Bin Wang, Haixiang Sun, Yali Hu
BACKGROUND What role should previous cesarean section play in affecting clinical pregnancy outcomes and avoiding the complications of in vitro fertilization? In this article, we focus on elective single-embryo transfer (eSET) versus double-embryo transfer (DET) and assess the clinical efficacy and safety of eSET in patients who have a previous cesarean scar. MATERIAL AND METHODS The pregnancy, delivery, and neonatal outcomes of 130 patients who had a previous cesarean scar and received in vitro fertilization-embryo transfer (IVF-ET) were retrospectively analyzed...
2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Sotirios H Saravelos, Grace Wing Shan Kong, Jacqueline Pui Wah Chung, Jennifer Sze Man Mak, Cathy Hoi Sze Chung, Lai Ping Cheung, Tin-Chiu Li
STUDY QUESTION: Does three-dimensional (3D) versus two-dimensional (2D) ultrasound (US) guidance during embryo transfer (ET) increase the ongoing pregnancy rate in women undergoing ART treatment. SUMMARY ANSWER: There is no significant difference in the ongoing pregnancy rate of women undergoing 3D versus 2D US-guided ET. WHAT IS KNOWN ALREADY: Studies have suggested that 3D US may confer additional benefits compared with 2D US during ET, although this has not been tested within the context of an RCT...
October 2016: Human Reproduction
Ji Sun Lee, Hyun-Hwa Cha, Ae Ra Han, Seong Goo Lee, Won Joon Seong
Heterotopic pregnancy is a rare and life-threatening condition which is defined as coexistent intrauterine and ectopic gestation. The risk of ectopic and heterotopic pregnancy is increasing due to the increased risk of multiple pregnancies with the aid of assisted reproductive technologies. However, it hardly happens in the setting of single embryo transfer, since single embryo transfer significantly reduces the incidence of multiple pregnancies. Surprisingly, we experienced a case of heterotopic pregnancy after a single embryo transfer caused by coincidental natural pregnancy during assisted reproductive technologies...
July 2016: Obstetrics & Gynecology Science
Berfu Demir, Gurkan Bozdag, Ozlem Sengul, Inci Kahyaoglu, Sezcan Mumusoglu, Dila Zengin
OBJECTIVE: To determine the impact of salpingectomy on the ovarian reserve. Comparisons are made with the contralateral side in patients with unilateral salpingectomy undergoing intracytoplasmic sperm injection (ICSI) cycles. STUDY DESIGN: Patients under 40 with unilateral salpingectomy and without history of ovarian surgery were selected for the multicentre retrospective study. Women with bilateral salpingectomy and history of endometriosis were excluded from the study...
March 26, 2016: Gynecological Endocrinology
Ji Hyun Jeon, Yu Im Hwang, Im Hee Shin, Chan Woo Park, Kwang Moon Yang, Hye Ok Kim
The purpose of this study was to investigate risk factors that are associated with heterotopic pregnancy (HP) following in vitro fertilization (IVF)-embryo transfer (ET) and to demonstrate the outcomes of HP after the surgical treatment of ectopic pregnancies. Forty-eight patients from a single center, who were diagnosed with HP between 1998 and 2012 were included. All of the patients had received infertility treatments, such as Clomid with timed coitus (n = 1, 2.1%), superovulation with intrauterine insemination (n = 7, 14...
July 2016: Journal of Korean Medical Science
Laura Londra, Caroline Moreau, Donna Strobino, Aarti Bhasin, Yulian Zhao
OBJECTIVE: To evaluate the association between different ovarian hyperstimulation protocols and ectopic pregnancy (EP) in in vitro fertilization (IVF) cycles in fresh autologous embryo transfer cycles in the United States between 2008 and 2011 as reported to the Society of Assisted Reproductive Technology (SART). DESIGN: Historical cohort study. SETTING: Not applicable. PATIENT(S): None. INTERVENTION(S): None...
September 1, 2016: Fertility and Sterility
Ali Aflatoonian, Mohammad Ali Karimzadeh Maybodi, Nastaran Aflatoonian, Nasim Tabibnejad, Mohammad Hossein Amir-Arjmand, Mehrdad Soleimani, Behrouz Aflatoonian, Abbas Aflatoonian
BACKGROUND: Despite of higher pregnancy rate after frozen embryo transfer (FET) which is accepted by the majority of researches, the safety of this method and its effect on neonatal outcome is still under debate. OBJECTIVE: The aim of this study was to evaluate pregnancy and neonatal outcome of FET compare to fresh cycles. MATERIALS AND METHODS: In this study,1134 patients using fresh ET and 285 women underwent FET were investigated regarding live birth as primary outcome and gestational age, birth weight, gender, multiple status, ectopic pregnancy, still birth and pregnancy loss as secondary outcomes...
March 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
Mariya Angelova Angelova, Emil Georgiev Kovachev, Ivan Kozovski, Yavor Dimitrov Kornovski, Stefan Vasilev Kisyov, Vilislava Robert Ivanova
The authors describe a rare case of secondary abdominal pregnancy after in vitro fertilization pre-embryo transfer (IVF-ET). Ultrasonography was applied to image ectopic gestational sac containing a yolk vesicle and located adjacent to the anterior uterine wall and left adnexa. Laparoscopy was done on the same day followed by sinistral salpingectomy due to tubal abortion indications. Intraabdominal examination showed chorionic structures penetrating pl. vesicouterina. Histological tests confirmed the EP diagnosis in the second material, i...
September 15, 2015: Open Access Macedonian Journal of Medical Sciences
Laurentiu Craciunas, Nikolaos Tsampras, Arri Coomarasamy, Nick Raine-Fenning
BACKGROUND: Subfertility affects 15% of couples and represents the inability to conceive naturally following 12 months of regular unprotected sexual intercourse. Assisted reproduction refers to procedures involving the in vitro handling of both human gametes and represents a key option for many subfertile couples. Most women undergoing assisted reproduction treatment will reach the stage of embryo transfer (ET) but the proportion of embryos that successfully implant following ET has remained small since the mid-1990s...
2016: Cochrane Database of Systematic Reviews
Lucky Sekhon, Joseph Lee, Shailja Mehta, Tanmoy Mukherjee, Benjamin Sandler, Alan B Copperman
INTRODUCTION: Analysis of ectopic pregnancies using traditional cytogenetic techniques has demonstrated a higher than expected increase in aneuploidy of these extrauterine implantation sites. Newer molecular techniques have greater diagnostic accuracy. We sought to evaluate the likeliness of a ectopic implantation of embryos that have undergone pre-implantation genetic screening (PGS). METHODS: Women undergoing in vitro fertilization (IVF) cycles from September 2010 to March 2015 were included...
May 2016: Obstetrics and Gynecology
Paolo Emanuele Levi Setti, Melita Moioli, Antonella Smeraldi, Elisa Cesaratto, Francesca Menduni, Stefania Livio, Emanuela Morenghi, Pasquale Patrizio
PURPOSE: The aim of this study was to provide a comprehensive follow-up of fetal and perinatal outcome and the incidence of congenital anomalies in babies born after fresh embryo transfers compared to those conceived spontaneously in infertile couples. METHODS: Retrospective comparative analysis of all clinical pregnancies from fresh cleavage-stage embryo transfer cycles (IVF and ICSI) compared with infertile patients who conceived spontaneously in the same time period (control)...
June 2016: Journal of Assisted Reproduction and Genetics
Xavier Santamaria, Sergio Cabanillas, Irene Cervelló, Cristina Arbona, Francisco Raga, Jaime Ferro, Julio Palmero, Jose Remohí, Antonio Pellicer, Carlos Simón
STUDY QUESTION: Could cell therapy using autologous peripheral blood CD133+ bone marrow-derived stem cells (BMDSCs) offer a safe and efficient therapeutic approach for patients with refractory Asherman's syndrome (AS) and/or endometrial atrophy (EA) and a wish to conceive? SUMMARY ANSWER: In the first 3 months, autologous cell therapy, using CD133+ BMDSCs in conjunction with hormonal replacement therapy, increased the volume and duration of menses as well as the thickness and angiogenesis processes of the endometrium while decreasing intrauterine adhesion scores...
May 2016: Human Reproduction
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