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paediatric orthopaedics

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https://www.readbyqxmd.com/read/27920806/hereditary-multiple-exostoses-a-review-of-clinical-appearance-and-metabolic-pattern
#1
REVIEW
Giovanni Beltrami, Gabriele Ristori, Guido Scoccianti, Angela Tamburini, Rodolfo Capanna
Hereditary multiple exostoses (HME) is an inherited genetic condition characterized by the presence of multiple exostoses (osteochondromas). MHE is a relatively rare autosomal dominant disorder, mainly caused by loss of function mutations in two genes: exostosin-1 (EXT1) and exostosin-2 (EXT2). These genes are linked to heparan sulfate (HS) synthesis, but the specific molecular mechanism leading to the disruption of the cartilage structure and the consequent exostoses formation is still not resolved. The aim of this paper is to encounter the main aspects of HME reviewing the literature, in order to improve clinical features and evolution, and the metabolic-pathogenetic mechanisms underlying...
May 2016: Clinical Cases in Mineral and Bone Metabolism
https://www.readbyqxmd.com/read/27878660/residual-bone-growth-after-lengthening-procedures
#2
Pierre Journeau, Pierre Lascombes, Dominique Barbier, Dmitry Popkov
The prognosis of limb length discrepancy is a major subject in paediatric orthopaedic surgery. The strategy depends on the prognosis and must be adapted to each patient. The residual growth of the lengthened segment often remains unknown, but is dependent on age, the percentage of lengthening and other factors. Using a large cohort of 150 children who had undergone bone lengthening procedures, we describe five patterns of post-intervention growth and identify factors that are favourable for normal residual growth...
November 23, 2016: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/27872768/hip-replacement-surgery-in-14-year-old-girl-with-factor-v-deficiency-haemostatic-treatment-and-thromboprophylaxis
#3
María Eva Mingot-Castellano, Josefina Pérez-Núñez, Lourdes Baeza-Montañez
Factor V (FV) is a pivotal coagulation factor present in plasma and platelets. It plays an essential role in secondary haemostasis acting as a cofactor in the prothrombinase complex, catalysing the conversion of prothrombin to thrombin. There is little evidence on the management of mayor orthopaedic surgery in paediatric or adolescents subjects with this coagulopathy and almost no information about thromboprophylaxis in these situations. We report a case of a hip replacement in a 14-year-old girl with moderate FV deficiency (0...
2016: Case Reports in Hematology
https://www.readbyqxmd.com/read/27826908/guided-growth-mechanism-and-reversibility-of-modulation
#4
REVIEW
Martin Gottliebsen, Juan Manuel Shiguetomi-Medina, Ole Rahbek, Bjarne Møller-Madsen
In paediatric orthopaedics, deformities and discrepancies in length of bones are key problems that commonly need to be addressed in daily practice. An understanding of the physiology behind developing bones is crucial for planning treatment. Modulation of the growing bone can be performed in a number of ways. Here, we discuss the principles and mechanisms behind the techniques. Historically, the first procedures were destructive in their mechanism but reversible techniques were later developed with stapling of the growth plate being the gold standard treatment for decades...
November 8, 2016: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/27821004/-nursing-is-where-i-belong
#5
(no author information available yet)
Why did you become a children's nurse? When I was training in the 1980s everyone did a paediatric placement and mine was on an orthopaedic children's ward. Many of the children were essentially 'well' children who were marooned in the beds. The atmosphere was markedly lighter than in other wards and I realised that children's nursing was the place for me.
November 8, 2016: Nursing Children and Young People
https://www.readbyqxmd.com/read/27658562/triclosan-containing-sutures-versus-ordinary-sutures-for-reducing-surgical-site-infections-in-children-a-double-blind-randomised-controlled-trial
#6
Marjo Renko, Niko Paalanne, Terhi Tapiainen, Matti Hinkkainen, Tytti Pokka, Sohvi Kinnula, Juha-Jaakko Sinikumpu, Matti Uhari, Willy Serlo
BACKGROUND: Surgical site infections (SSIs) are a pervasive problem in surgery. Sutures coated or impregnated with triclosan might reduce the occurrence of SSIs, but evidence of their efficacy is limited, especially in children. METHODS: We designed a randomised, double-blind, controlled trial in patients who underwent elective or daytime emergency surgery at Oulu University Hospital (Oulu, Finland). We included children younger than 18 years staying in the paediatric surgery and orthopaedics ward for any elective or emergency surgery during the daytime and with anticipated use of absorbing sutures...
September 19, 2016: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/27617713/factors-influencing-the-postgraduate-training-choices-of-medical-interns-and-junior-medical-officers-at-the-georgetown-public-hospital-corporation-guyana
#7
Y Hendricks, A O Amata
Objective: The aim of our study was to determine the specialty preferences and the reasons for those choices among medical interns and junior medical doctors at the Georgetown Public Hospital Corporation (GPHC), Guyana. Methods: A cross-sectional study of recent medical graduates at GPHC using anonymous self-administered questionnaires. Results: Of the study population of 66, 60 filled questionnaires were returned (response rate of 91.5%)...
December 28, 2015: West Indian Medical Journal
https://www.readbyqxmd.com/read/27594577/the-impact-of-a-unique-knowledge-translation-programme-implemented-in-a-large-multisite-paediatric-hospital
#8
Catie Christensen, David Wessells, Michelle Byars, James Marrie, Shaun Coffman, Erin Gates, Mitch Selhorst
BACKGROUND AND PURPOSE: Physical therapists (PTs) display positive attitudes toward evidence-based practice (EBP), and implementing it can improve patient outcomes and reduce costs. However, barriers can lead to inconsistent use of EBP. The objectives of this manuscript are to (i) describe the initiation and revisions to a knowledge translation (KT) programme, (ii) assess staff participation in KT, and (iii) evaluate availability, internal use and external dissemination of evidence-based recommendations and research...
September 4, 2016: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/27593087/digital-audio-recordings-improve-the-outcomes-of-patient-consultations-a-randomised-cluster-trial
#9
Maiken Wolderslund, Poul-Erik Kofoed, René Holst, Mette Axboe, Jette Ammentorp
OBJECTIVES: To investigate the effects on patients' outcome of the consultations when provided with: a Digital Audio Recording (DAR) of the consultation and a Question Prompt List (QPL). METHODS: This is a three-armed randomised controlled cluster trial. One group of patients received standard care, while the other two groups received either the QPL in combination with a recording of their consultation or only the recording. Patients from four outpatient clinics participated: Paediatric, Orthopaedic, Internal Medicine, and Urology...
August 29, 2016: Patient Education and Counseling
https://www.readbyqxmd.com/read/27583060/incidence-and-risk-factors-of-rachitic-genu-varus-in-preschool-children-in-a-paediatric-health-institute-in-egypt-as-one-of-the-developing-countries
#10
Sherif N G Bishay, Mostafa H A El-Sherbini, Amre A Azzam, Ashraf A Lotfy
BACKGROUND: Rachitic genu varus is one of the common conditions among the Egyptian children, despite the shinning sun of Egypt all the year. PURPOSE: The aim of the study was to estimate the incidence of rachitic genu varus among the Egyptian children, and to assess the risk factors contributing to it. PATIENTS AND METHODS: This prospective study recruited a total of 250 consecutive children, being 130 males and 120 females, with rachitic bow legs or genu varus, between 2 - 4 years of age, together with 250 controls of the same age group, out of a total number of 1900 children with other types of rickets, and other children's orthopaedic diseases, who presented to the National Institute of Neuromotor System in Egypt between September 2014 to September 2015...
2016: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/27578377/treatment-of-pediatric-femoral-shaft-fractures-by-stainless-steel-and-titanium-elastic-nail-system-a-randomized-comparative-trial
#11
Tank Gyaneshwar, Rustagi Nitesh, Tomar Sagar, Kothiyal Pranav, Nitesh Rustagi
PURPOSE: Literature suggests that the lower modulus of elasticity of titanium makes it ideal for use in children compared with stainless steel. Better fracture stability was observed in association with titanium nails on torsional and axial compression testing. However, stainless steel nails are stiffer than titanium counterparts, which may provide a rigid construct when fixing paediatric femoral shaft fractures. Complications have been observed more frequently by various researchers when titanium nails are used for fracture fixation in patients with increasing age or weight...
August 1, 2016: Chinese Journal of Traumatology, Zhonghua Chuang Shang za Zhi
https://www.readbyqxmd.com/read/27540187/the-potential-for-pharmacists-to-manage-children-attending-emergency-departments
#12
David Terry, Konstantinos Petridis, Matt Aiello, Anthony Sinclair, Chi Huynh, Louis Mazard, Hirminder Ubhi, Alex Terry, Elizabeth Hughes
AIM: There have been concerns about maintaining appropriate clinical staff levels in Emergency Departments in England.1 The aim of this study was to determine if Emergency Department attendees aged from 0-16 years could be managed by community pharmacists or hospital independent prescriber pharmacists with or without further advanced clinical practice training. METHOD: A prospective, 48 site, cross-sectional, observational study of patients attending Emergency Departments (ED) in England, UK was conducted...
September 2016: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/27451421/ipsilateral-fibular-transfer-as-a-salvage-procedure-for-large-traumatic-tibial-defects-in-children-in-an-austere-environment
#13
Andre J Keenan, O J F Keenan, C Tubb, A M Wood, T Rowlands, S E Christensen
Large tibial defects present a challenging scenario for the orthopaedic surgeon, particularly in the paediatric patient. Most management options, such as the vascularised fibular graft or Ilizarov technique, require microsurgical techniques or specialist equipment. In an austere environment, acute shortening or limb amputation may be most appropriate. However, limb salvage may be achieved by ipsilateral fibular transfer. In a one-stage operation, the fibular graft is harvested and either placed in the tibial defect in an intramedullary position or secured to the tibia with screws...
December 2016: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/27432464/clinical-significance-of-anterior-humeral-line-in-supracondylar-humeral-fractures-in-children
#14
Hsuan-Kai Kao, Wei-Chun Lee, Wen-E Yang, Chia-Hsieh Chang
INTRODUCTION: Anterior humeral line (AHL) location is commonly used to evaluate sagittal alignment after fracture reduction in children with supracondylar humeral fractures. However, the position of the AHL for acceptable fracture reduction has not been validated by clinical outcome. The purpose of this study was to investigate the relationship between the location of AHL and range of elbow motion. PATIENTS AND METHODS: We retrospectively reviewed 101 children who underwent closed reduction and percutaneous pinning for Gartland type III supracondylar humeral fractures between January 2009 and June 2014...
July 1, 2016: Injury
https://www.readbyqxmd.com/read/27416574/glioblastoma-and-abo-blood-groups-further-evidence-of-an-association-between-the-distribution-of-blood-group-antigens-and-brain-tumours
#15
Mohammed Z Allouh, Mohammed M Al Barbarawi, Mohammad Y Hiasat, Mohammed A Al-Qaralleh, Emad I Ababneh
BACKGROUND: Glioblastoma is a highly malignant brain tumour that usually leads to death. Several studies have reported a link between the distribution of ABO blood group antigens and a risk of developing specific types of cancer, although no consensus has been reached. This study aims to investigate the relationship between the distribution of ABO blood group antigens and the incidence of glioblastoma. MATERIALS AND METHODS: The study cohort consisted of 115 glioblastoma patients who were diagnosed at King Abdullah University Hospital, Jordan, between 2004 and 2015...
June 30, 2016: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/27412805/musculoskeletal-infections-associated-with-citrobacter-koseri
#16
T A Kwaees, Z Hakim, C Weerasinghe, P Dunkow
Introduction Citrobacter koseri is a well known cause of central nervous system infections in the paediatric setting. Musculoskeletal infections caused by C koseri are rare, with only 14 previously reported cases. We present the first recorded case of C koseri induced septic arthritis of the knee along with a review of the literature. Methods A search of the PubMed, Embase(®) and Google Scholar™ databases was undertaken. Only complete or near complete cases were reviewed. Findings Fourteen musculoskeletal infections were identified...
September 2016: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/27384452/efficacia-della-valva-di-posizione-con-scarico-al-tallone-br-nei-bambini-portatori-di-apparecchio-gessato-agli-arti-inferiori-br-trial-randomizzato-controllato-in-aperto
#17
Luisa Veronesi, Elisa Pia Merola, Miguel Schiavone, Cristiana Forni
: . Efficacy of splint with heel off-loaded in children with lower limbs plaster cast. Randomised open label trial. INTRODUCTION: Plasters cast are medical devices widely used in paediatric orthopaedics; however, few studies have addressed the occurrence and prevention of device-related complications. AIM: To evaluate whether positioning a custom made splint with heel off-loaded, would relieve pain, reduce care interventions, the materials to maintain heel unloading position and, at the same time, improve comfort and reduce pressure sores in children with lower limb plaster...
April 2016: Assistenza Infermieristica e Ricerca: AIR
https://www.readbyqxmd.com/read/27352865/risk-stratification-for-the-recurrence-of-trigger-thumb-after-surgical-release-in-the-paediatric-patient
#18
D S Edwards, R H Richards
Trigger thumb, or stenosing tenovaginitis, is a relatively uncommon condition affecting the flexor pollicis longus tendon of children. The condition is characterized by the formation of a nodule within the tendon and thickening of the tendon sheath as it passes through the flexor pulley of the thumb at the level of the metacarpo-phalangeal joint. The optimum age for surgical intervention continues to be discussed. The aim of this study is to establish the temporal relationship and surgical variables to determine factors that may contribute to recurrence of the condition...
August 2016: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/27333467/efficacy-and-safety-of-long-acting-recombinant-fusion-protein-linking-factor-ix-with-albumin-in-haemophilia-b-patients-undergoing-surgery
#19
C Négrier, F Abdul Karim, L M Lepatan, A Lienhart, M F López-Fernández, J Mahlangu, I Pabinger, Y Li, D Wolko, C Voigt, I Jacobs, E Santagostino
INTRODUCTION: Recombinant factor IX fusion protein (rIX-FP) has been developed to improve the pharmacokinetic (PK) profile of factor IX (FIX), allowing maintenance of desired FIX activity between injections at extended intervals, ultimately optimizing haemophilia B treatment. AIM: To determine the efficacy and safety of rIX-FP in the perioperative setting. METHODS: Subjects were adult and paediatric patients with severe to moderately severe haemophilia B (FIX ≤ 2%) participating in three Phase III clinical trials and undergoing a surgical procedure...
July 2016: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/27239018/hip-arthrodiastasis-in-legg-calv%C3%A3-perthes-disease
#20
I Aguado-Maestro, J C Abril, A Bañuelos Diaz, M García Alonso
INTRODUCTION AND OBJECTIVE: Arthrodiastasis consists of the mobilisation of the hip while distracted by a hinged distractor. The aim of our study is to show the results of the treatment of late-onset Perthes disease with this technique in our institution. MATERIAL AND METHODS: Ambispective review of all the cases that underwent this surgery in our Department of Paediatric Orthopaedics between 2010 and 2014 with the following inclusion criteria: patients over 8 years old, with minimal deformity, and poor prognosis...
July 2016: Revista Española de Cirugía Ortopédica y Traumatología
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