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https://www.readbyqxmd.com/read/25487232/postoperative-morbidity-and-mortality-after-pneumonectomy-a-30-year-experience-of-2064-consecutive-patients
#1
MULTICENTER STUDY
Ciprian Pricopi, Pierre Mordant, Caroline Rivera, Alex Arame, Christophe Foucault, Antoine Dujon, Françoise Le Pimpec Barthes, Marc Riquet
OBJECTIVES: We examined whether the changes in clinical practice with time correlated with the changes in the 90-day mortality following pneumonectomy. METHODS: The clinical records of consecutive patients undergoing pneumonectomy in two French centres from 1980 to 2009 were prospectively collected. The 90-day postoperative course was retrospectively studied according to clinical characteristics, underlying diseases, type of surgery and time-period (1980-1989; 1990-1999 or 2000-2009)...
March 2015: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/25454825/prognostic-factors-after-surgical-resection-of-n1-non-small-cell-lung-cancer
#2
P Mordant, C Pricopi, A Legras, A Arame, C Foucault, A Dujon, F Le Pimpec-Barthes, M Riquet
OBJECTIVES: Non-small cell lung carcinoma (NSCLC) with N1 involvement is associated with 5-year survival rates ranging from 7% to 55%. Numerous factors have been independently reported to explain this heterogeneous prognosis, but their relative weight on long-term survival is unknown. METHODS: Patients who underwent surgical resection for NSCLC in two French centers from 1993 to 2010 were prospectively recorded and retrospectively reviewed. The overall survival (OS) of patients undergoing first-line surgery for pN1 disease was analyzed according to the type of extension, number of metastatic LN, number and anatomic location of metastatic stations...
May 2015: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/25131368/-pneumonectomy-for-benign-disease-indication-and-factors-affecting-the-postoperative-course
#3
COMPARATIVE STUDY
A Arame, C Rivera, P Mordant, C Pricopi, C Foucault, A Badia, F Le Pimpec Barthes, M Riquet
Pneumonectomy for benign disease is rare but may generate more postoperative morbimortality than when performed for lung cancer. We questioned this assessment and retrospectively reviewed 1436 pneumonectomies and 54 completions of which 82 and 10 performed for benign disease (5.7% and 18.5%, respectively): left n=65 and right n=27. Indications were: post-tuberculosis destroyed lung (n=37), aspergilloma (n=18), bronchiectasis (n=19), infection (n=5), congenital malformations (n=5), inflammatory pseudotumor (n=3), trauma (n=2), post-radiation (n=2) and mucormycosis (n=1)...
February 2015: Revue de Pneumologie Clinique
https://www.readbyqxmd.com/read/24932506/-place-of-bilobectomy-in-pulmonary-oncology-and-prognostic-factors-in-nsclc
#4
A Arame, C Rivera, C Pricopi, P Mordant, M Abdennadher, C Foucault, A Dujon, F Le Pimpec Barthes, M Riquet
INTRODUCTION: Bilobectomy may be performed for different reasons and lung tumors. There are still controversies regarding the results of this procedure. We reviewed our experience of bilobectomy to evaluate the particularities of this resection. METHODS: The clinical files of patients operated on for lung tumors in two French centers between 1980 and 2009 were prospectively recorded and retrospectively analyzed. The characteristics, management, pathology, and survival after right-sided resections for non-small cell lung cancer (NSCLC) were then compared...
October 2014: Revue de Pneumologie Clinique
https://www.readbyqxmd.com/read/24875885/is-the-lymphatic-drainage-of-lung-cancer-lobe-specific-a-surgical-appraisal
#5
Marc Riquet, Caroline Rivera, Ciprian Pricopi, Alex Arame, Pierre Mordant, Christophe Foucault, Antoine Dujon, Françoise Le Pimpec-Barthes
OBJECTIVES: Nowadays, early-stage lung cancers are more frequently encountered. Selective lymph node (LN) dissection based on lobe-specific lymphatic pathway has been proposed. Our aim was to study nodal involvement according to tumour location. METHODS: We reviewed 1779 lobectomized patients and analysed their pathological characteristics according to tumour location: Group 1 (G1), right upper lobe; Group 2 (G2), right middle lobe; Group 3 (G3), right lower lobe; Group 4 (G4), left upper division; Group 5 (G5), lingula; Group 6 (G6), left lower lobe...
March 2015: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/24581796/-lung-cancer-in-the-elderly-what-about-surgery
#6
REVIEW
C Rivera, M Gisselbrecht, C Pricopi, E Fabre, P Mordant, A Badia, F Le Pimpec-Barthes, M Riquet
Geriatric oncology is a rapidly expanding domain because of the deep epidemiological changes of the last decades related to the ageing of the population. Lung cancer treatment in patients 75 years and over is a major issue of thoracic oncology. Curative surgery remains the treatment offering the best survival rates to the patient whatever his age. The important variability observed within the elderly forces us to take into account their specificities, in particular for ageing physiology and associated comorbidities...
February 2014: Revue de Pneumologie Clinique
https://www.readbyqxmd.com/read/24566033/-lung-cancer-with-heart-failure-a-cardiac-and-thoracic-surgeon-s-collaboration
#7
C Pricopi, F Alimi, P Achouh, P Mordant, F Le Pimpec-Barthes, A Arame, A Badia, M Riquet
Surgical resection is a validated therapeutic option for selected cases of pulmonary tumors invading the important mediastinal structures (caval vein, atrium, aorta or supra-aortic trunks). Here, we present a patient with a necrosed pulmonary tumor invading the left atrium, causing cardiac insufficiency. A complete surgical resection under extracorporeal circulation was performed by the thoracic and cardiac teams. Admitted in a bed-ridden state, the patient was discharged completely rehabilitated on postoperative day 13...
February 2014: Revue de Pneumologie Clinique
https://www.readbyqxmd.com/read/24566031/-lymphatic-spread-of-lung-cancer-anatomical-lymph-node-chains-unchained-in-zones
#8
REVIEW
M Riquet, C Rivera, L Gibault, C Pricopi, P Mordant, A Badia, A Arame, F Le Pimpec Barthes
Lung cancer is characterized by its lymphophilia. Its metastatic spread mainly occurs by tumor cells lymphatic drainage into the blood circulation. Initially, the lymph node TNM classification was based on clinical and therapeutic considerations, particularly concerning N2 involvement. The goals were to avoid futile exploratory thoracotomies without lung resection, to provide more accurate data from mediastinoscopy, and to take into account the radiation therapy fields. Since 1997, the international lymph node classification was more used to analyse the disparities within N1 and N2 groups...
February 2014: Revue de Pneumologie Clinique
https://www.readbyqxmd.com/read/24566030/-impact-of-induction-therapies-on-pathology-and-outcome-after-surgical-resection-of-non-small-lung-cancer-a-30-year-experience-of-859-patients
#9
P Mordant, É Fabre, L Gibault, A Arame, C Pricopi, A Dujon, F Le Pimpec-Barthes, M Riquet
UNLABELLED: The management of localized non-small cell lung cancer (NSCLC) has been modified over the last decades, with induction therapies being increasingly recommended as a prerequisite to surgical resection. However, the relative impact of chemo- and chemoradiotherapy on tumours' pathology and patients' survival is still discussed. METHODS: We set a retrospective study including every patient who underwent surgical resection for NSCLC in 2 French centres from 1980 to 2009...
February 2014: Revue de Pneumologie Clinique
https://www.readbyqxmd.com/read/24566026/-diaphragmatic-palsy-and-dysfunction-from-physiology-to-surgery
#10
REVIEW
F Le Pimpec-Barthes, C Pricopi, P Mordant, A Arame, A Badia, B Grand, P Bagan, A Hernigou, M Riquet
The clinical presentations of diaphragm dysfunctions vary according to etiologies and unilateral or bilateral diseases. Elevation of the hemidiaphragm from peripheral origins, the most frequent situation, requires a surgical treatment only in case of major functional impact. Complete morphological and functional analyses of the neuromuscular chain and respiratory tests allow the best selection of patients to be operated. The surgical procedure may be proposed only when the diaphragm dysfunction is permanent and irreversible...
February 2014: Revue de Pneumologie Clinique
https://www.readbyqxmd.com/read/24365214/is-the-rate-of-pneumonectomy-higher-in-right-middle-lobe-lung-cancer-than-in-other-right-sided-locations
#11
COMPARATIVE STUDY
Caroline Rivera, Pierre Mordant, Ciprian Pricopi, Alex Arame, Christophe Foucault, Antoine Dujon, Françoise Le Pimpec Barthes, Marc Riquet
BACKGROUND: Historically, right middle lobe (RML) non-small cell lung cancer (NSCLC) has been reported to be associated with a higher rate of pneumonectomy than other right-sided locations. Because this would discourage minimally invasive approaches in RML-NSCLC, we sought to update this assertion through the study of a large surgical series. METHODS: Clinical records of patients who underwent operations for right-sided NSCLC in 2 French surgical centers were prospectively entered and retrospectively reviewed...
February 2014: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/24210159/-metastatic-thoracic-lymph-node-carcinoma-from-extra-thoracic-malignancy-or-from-unknown-primary-site
#12
P Bagan, P Mordant, C Pricopi, F Le Pimpec Barthes, M Riquet
Malignant mediastinal lymph nodes without pulmonary disease may be lymphomatous or the metastases from thoracic or extrathoracic malignancy. More rarely, metastatic lymph nodes are without primary site. Surgery is generally diagnostic, restricted to confirming the metastatic process, because of too numerous and disseminated or unresectable lymph nodes. Radical surgery consisting in lymphadenectomy can be effective in case of mediastinal lymph node malignancy without other extra- and intrathoracic disease. We observed in our experience and in several case reports long-term good results in such cases...
December 2013: Revue de Pneumologie Clinique
https://www.readbyqxmd.com/read/24183293/-lymphatics-and-lung-transplantation-a-review
#13
REVIEW
F Le Pimpec-Barthes, P Mordant, C Pricopi, L Gibaud, A Arame, A Cazes, A Badia, A Hernigou, M Riquet
The role of lymph circulation in lung transplantation (LTx) has not really been studied since the first animal models, which allowed the development of solid organ transplantations. However, the oedema observed in the grafts immediately after LTx often remains unpredictable and unexplained. Although it is an integral part of the entity called "primary graft failure". Despite its multifactor aspects making the interpretation difficult, the possibility of a change in the lymph circulation is proposed to explain an oedema occurrence...
February 2014: Revue de Pneumologie Clinique
https://www.readbyqxmd.com/read/24132299/a-review-of-250-ten-year-survivors-after-pneumonectomy-for-non-small-cell-lung-cancer
#14
REVIEW
Marc Riquet, Pierre Mordant, Ciprian Pricopi, Antoine Legras, Christophe Foucault, Antoine Dujon, Alex Arame, Françoise Le Pimpec-Barthes
OBJECTIVES: During the last decades, pneumonectomy has been increasingly seen as a risky procedure, first reserved for tumours not amenable to lobectomy, and now discouraged even in advanced stages of non-small-cell lung cancer (NSCLC). Our purpose was to assess the long-term survival following pneumonectomy for NSCLC and its prognostic factors. METHODS: We set a retrospective study including every patient who underwent a pneumonectomy for NSCLC in 2 French centres from 1981 to 2002...
May 2014: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/23523433/-anatomy-micro-anatomy-and-physiology-of-the-lymphatics-of-the-lungs-and-chest-wall
#15
REVIEW
M Riquet, P Mordant, C Pricopi, K Achour, F Le Pimpec Barthes
The thoracic lymphatic vessels are pulsating channels which drain actively the fluid of lung parenchyma interstitium and pleural cavities. Their unidirectional valves that avoid reflux of contents, direct the current of fluid to the connection of thoracic duct to subclavian vein or to the thoracic duct itself by these pulsations. The ascending parietal and visceral currents have anastomoses between them. The parietal currents (internal thoracic anteriorly, external axillaries in lateral and paravertebral in posterior) drain the lymph of thoracic wall...
April 2013: Revue de Pneumologie Clinique
https://www.readbyqxmd.com/read/22440301/-the-place-of-surgery-in-metastatic-non-small-cell-lung-cancer
#16
F Le Pimpec Barthes, P Mordant, C Pricopi, C Foucault, A Dujon, M Riquet
BACKGROUND: Metastatic lung cancer may be M1a (contralateral lung nodule, malignant pleural or pericardial effusion or pleural nodules) or M1b (distant metastases). Surgery is not usually considered in their treatment. METHOD: After exclusion of contralateral lung nodules, we reviewed the demographics, management, survival and prognostic factors in M1 patients, among a total of 4668 patients who underwent surgery for lung cancer between January 1983 and December 2006...
March 2012: Revue des Maladies Respiratoires
https://www.readbyqxmd.com/read/22223700/which-metastasis-management-allows-long-term-survival-of-synchronous-solitary-m1b-non-small-cell-lung-cancer
#17
Pierre Mordant, Alex Arame, Florence De Dominicis, Ciprian Pricopi, Christophe Foucault, Antoine Dujon, Françoise Le Pimpec-Barthes, Marc Riquet
UNLABELLED: OBJECTIVES; Patients with extrathoracic synchronous solitary metastasis and non-small cell lung cancer (NSCLC) are rare. The effectiveness of both tumour sites resection is difficult to evaluate because of the high variability among clinical studies. We reviewed our experience regarding the management and prognosis of these patients. METHODS: The charts of 4668 patients who underwent lung cancer surgery from 1983 to 2006 were retrospectively reviewed...
March 2012: European Journal of Cardio-thoracic Surgery
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