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https://www.readbyqxmd.com/read/29453931/comparison-of-return-to-pre-injury-sport-after-10-mm-size-bone-patellar-tendon-bone-bptb-versus-8-mm-hamstring-anterior-cruciate-ligament-reconstruction-a-retrospective-study-with-a-two-year-follow-up
#1
Rimtautas Gudas, Rokas Jurkonis, Alfredas Smailys
BACKGROUND The aim of this study was to evaluate the reconstruction of a torn anterior cruciate ligament (ACL) with 10 mm diameter BPTB (bone-patellar tendon-bone) autograft versus 8 mm HT (hamstring tendon) autografts, to compare the ability to restore pre-injury sports activities and reduce revision risk after these procedures. MATERIAL AND METHODS A prospective clinical review was performed to compare results of patients who underwent primary anatomical ACLR with 10 mm BPTB autografts with patients who underwent 8 mm diameter HT autografts, between January 2011 and January 2014...
February 17, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29447959/effects-of-maturation-and-advanced-glycation-on-tensile-mechanics-of-collagen-fibrils-from-rat-tail-and-achilles-tendons
#2
Rene B Svensson, Stuart T Smith, Patrick J Moyer, S Peter Magnusson
Connective tissues are ubiquitous throughout the body and consequently affect the function of many organs. In load bearing connective tissues like tendon, the mechanical functionality is provided almost exclusively by collagen fibrils that in turn are stabilized by covalent cross-links. Functionally distinct tendons display different cross-link patterns, which also change with maturation, but these differences have not been studied in detail at the fibril level. In the present study, a custom built nanomechanical test platform was designed and fabricated to measure tensile mechanics of individual fibrils from rat tendons...
February 12, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29447021/release-of-pro-inflammatory-cytokines-from-muscle-and-bone-causes-tenocyte-death-in-a-novel-rotator-cuff-in-vitro-explant-culture-model
#3
Brianne K Connizzo, Alan J Grodzinsky
Tendinopathy is a significant clinical problem thought to be associated with altered mechanical loading. Explant culture models allow researchers to alter mechanical loading in a controlled in vitro environment while maintaining tenocytes in their native matrix. However, current models do not accurately represent commonly injured tendons, ignoring contributions of associated musculature and bone, as well as regional collagen structure. This study details the characterization of a mouse rotator cuff explant culture model, including bone, tendon, and muscle (BTM)...
February 15, 2018: Connective Tissue Research
https://www.readbyqxmd.com/read/29445933/multimodality-imaging-of-subacromial-impingement-syndrome
#4
REVIEW
Lionel Pesquer, Sophie Borghol, Philippe Meyer, Mickael Ropars, Benjamin Dallaudière, Pierre Abadie
Subacromial impingement syndrome results from irritation of the tendons of the rotator cuff muscles in the subacromial space and may manifest as a range of pathologies. However, subacromial impingement is a dynamic condition for which imaging reveals predisposing factors but no pathognomonic indicators. Also, the usual imaging features of subacromial impingement may be seen in symptomatic and asymptomatic patients. Therefore, imaging is able to detect tears and describe the risk factors of impingement but cannot confirm subacromial impingement...
February 14, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29445875/interference-screw-insertion-angle-has-no-effect-on-graft-fixation-strength-for-insertional-achilles-tendon-reconstruction
#5
Ziying Wu, Hongyun Li, Shiyi Chen, Kui Ma, Shengkun Li, Peng Zhang, Yinghui Hua
PURPOSE: To compare the effect of two interference screw insertion angles on the biomechanical properties of the insertional Achilles tendon (IAT) reconstruction. METHODS: Nine matched pairs of fresh-frozen human cadaveric Achilles tendon specimens were randomized to two groups with interference screw insertion angles of 60° and 120°. The IAT reconstruction was performed by fixing the graft tendon with the interference screw. Each specimen was loaded to failure...
February 14, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29438635/twenty-year-follow-up-study-comparing-operative-versus-nonoperative-treatment-of-anterior-cruciate-ligament-ruptures-in-high-level-athletes
#6
Daan T van Yperen, Max Reijman, Eline M van Es, Sita M A Bierma-Zeinstra, Duncan E Meuffels
BACKGROUND: An anterior cruciate ligament (ACL) rupture has major consequences at midterm follow-up, with an increasing chance of developing an old knee in a young patient. The long-term (≥20 years) effects of the operative and nonoperative treatment of ACL ruptures are still unclear. PURPOSE: To compare the long-term treatment outcomes of operative versus nonoperative treatment of ACL ruptures in high-level athletes. STUDY DESIGN: Cohort study; Level of evidence, 2...
February 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29432502/comparison-of-the-effect-of-intravenous-anesthetics-used-for-anesthesia-during-electroconvulsive-therapy-on-the-hemodynamic-safety-and-the-course-of-ect
#7
REVIEW
Rafał Wojdacz, Łukasz Święcicki, Anna Antosik-Wójcińska
Electroconvulsive therapy (ECT) is the treatment method widely used in psychiatric disorders such as depression, bipolar disorder, schizophrenia and schizoaffective disorder. The advantage of ECT is therapeutic response that occurs significantly earlier than during pharmacotherapy. Initially ECTwas used without anesthesia. Then, in the 1950s procedures with general anesthesia were introduced to reduce the complications that may occur during a seizure caused by ECT, such as broken bones, teeth, tendon rupture, muscle damage...
December 30, 2017: Psychiatria Polska
https://www.readbyqxmd.com/read/29430399/associated-reconstruction-of-anterior-cruciate-and-anterolateral-ligaments-with-single-asymmetric-hamstring-tendons-graft
#8
Alejandro Espejo-Baena, Alejandro Espejo-Reina, Abel Gómez-Cáceres, Maria Josefa Espejo-Reina, Jaime Dalla Rosa-Nogales
The anterior cruciate ligament (ACL) rupture is a common disease that accounts for 250,000 cases/year in the United States. The anterolateral ligament (ALL) has been suggested to be an important restraint for rotational instability, and its reconstruction provides a reinforcement to the ACL reconstruction in this aspect, especially in high-demand athletes and in knees with high-grade pivot shift. Different techniques for associated ACL and ALL reconstruction have been described, but the ideal technique remains unclear...
October 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/29430392/surgical-technique-to-bring-down-the-patellar-height-and-to-reconstruct-the-tendon-for-chronic-patellar-tendon-rupture
#9
Kengo Harato, Shu Kobayashi, Kazuhiko Udagawa, Yu Iwama, Ko Masumoto, Hiroyuki Enomoto, Yasuo Niki
Although surgical treatment is the gold standard for chronic patellar tendon rupture, the technique of patellar tendon reconstruction is still difficult. Basically, good clinical results of surgical repair for acute patellar tendon rupture have been reported. However, the results of reconstructive surgery for chronic patellar tendon rupture are still inconsistent. Some surgical options have been previously reported. For example, surgeons need to choose between 1- and 2-stage reconstruction. Furthermore, contralateral bone-tendon-bone graft, ipsilateral semitendinosus tendon graft, Achilles tendon allograft, and an artificial ligament have been used to reconstruct the patellar tendon...
October 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/29429762/enthesitis-a-hallmark-of-psoriatic-arthritis
#10
REVIEW
Gurjit S Kaeley, Lihi Eder, Sibel Z Aydin, Marwin Gutierrez, Catherine Bakewell
OBJECTIVE: To describe the growing importance of enthesitis in patients with psoriatic arthritis (PsA) and discuss the advantages and disadvantages of clinical and imaging methods currently used to assess enthesitis. METHODS: PubMed literature searches were conducted using the terms psoriatic arthritis, entheses, enthesitis, pathology, imaging, ultrasound, magnetic resonance imaging, clinical, and indices. Articles were deemed relevant if they provided insight into the pathology, monitoring, and/or diagnosis of enthesitis in PsA, or if they discussed clinical or imaging indices used to assess enthesitis...
January 6, 2018: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/29428042/extremity-vascular-injury-management-good-outcomes-using-selective-referral-to-vascular-surgeons
#11
Shabnam Hafiz, Elizabeth A Zubowicz, Chadi Abouassaly, John J Ricotta, Jack A Sava
Revascularization after extremity vascular injury has long been considered an important skill among trauma surgeons. Increasingly, some trauma surgeons defer vascular repair in response to training or practice patterns. This study was designed to document results of extremity revascularization surgery to evaluate trauma surgeon outcomes and judicious referral of more complex injuries to vascular surgeons (VAS). The trauma registry of an urban level I trauma center was used to identify all patients from 2003 to 2013 who underwent an early (<24 hours) procedure for urgent management of acute injury to extremity vessels...
January 1, 2018: American Surgeon
https://www.readbyqxmd.com/read/29427945/bioactive-calcium-phosphate-silicate-ceramic-surface-modified-plga-for-tendon-to-bone-healing
#12
Jingshu Guo, Congqin Ning, Xuanyong Liu
Due to the dissimilar features between the tendon and bone, tendon to bone healing is the most challenging problems in sports medicine. In the present work, a novel bioactive calcium phosphate silicate ceramic (CPS) was coated on the surface of PLGA films using electron beam evaporation (EBE) technique to prepare a tailorable composite film with layered chemical composition similar to tendon-bone interface. The physicochemical behaviors of the CPS-PLGA composite films were characterized and the cytocompatibility were also investigated...
February 4, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29427745/enhanced-tendon-to-bone-repair-through-adhesive-films
#13
Stephen W Linderman, Mikhail Golman, Thomas R Gardner, Victor Birman, William N Levine, Guy M Genin, Stavros Thomopoulos
Tendon-to-bone surgical repairs have unacceptably high failure rates, possibly due to their inability to recreate the load transfer mechanisms of the native enthesis. Instead of distributing load across a wide attachment footprint area, surgical repairs concentrate shear stress on a small number of suture anchor points. This motivates development of technologies that distribute shear stresses away from suture anchors and across the enthesis footprint. Here, we present predictions and proof-of-concept experiments showing that mechanically-optimized adhesive films can mimic the natural load transfer mechanisms of the healthy attachment and increase the load tolerance of a repair...
February 7, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29427218/short-to-mid-term-outcomes-of-anatomic-mcl-reconstruction-with-achilles-tendon-allograft-after-multiligament-knee-injury
#14
Ian J Barrett, Aaron J Krych, Ayoosh Pareek, Nicholas R Johnson, Diane L Dahm, Michael J Stuart, Bruce A Levy
PURPOSE: Multiple techniques have been described in the literature for reconstruction of the medial collateral ligament. The purpose of this study is to describe functional outcome, range of motion, and knee stability following anatomic MCL reconstruction utilizing an Achilles tendon bone allograft after multiligament knee injury. METHODS: A comprehensive search of a single-hospital multiligament knee injury (MLKI) procedural database was conducted to identify all patients that underwent reconstruction of the MCL utilizing an Achilles tendon bone allograft and with 2-year clinical follow-up...
February 9, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29426312/anterior-cruciate-ligament-reconstruction-with-quadriceps-tendon-patellar-bone-allograft-matched-case-control-study
#15
Yoon-Ho Kwak, Sahnghoon Lee, Myung Chul Lee, Hyuk-Soo Han
BACKGROUND: Quadriceps tendon-patellar bone (QTPB) autograft is an excellent graft option with good clinical outcome. Use of QTPB autografts have increased because they minimize donor-site morbidity including anterior knee pain, while providing adequate mechanical strength. Although, there were many clinical results about allografts that used in anterior cruciate ligament (ACL) reconstruction, it have never been reported about the clinical outcome of ACL reconstruction with QTPB allograft...
February 9, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29424175/-experimental-study-on-staphylococcal-enterotoxin-promoting-tendon-bone-healing-after-reconstruction-of-anterior-cruciate-ligament-in-rabbits
#16
Chun-Bao Li, Chao Xue, Wei Qi, Ning Wang, Jing Xue, Xiao-Yong Wu, Juan-Li Zhu, Yang Liu, Yu-Jie Liu
OBJECTIVE: To explore highly agglutinative staphylococcin (HAS) pomoting on tendon-bone healing after reconstruction of anterior cruciate ligament(ACL) in rabbits. METHODS: Animal model of ACL reconstruction in 24 mature New Zealand white rabbits(3 months, 2.56 kg on average, either gender) were established using autologous digital long extensor tendon and randomly classified into 2 groups(HAS and control group), 12 rabbits for each group. HAS group was separately injected 0...
June 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29424163/-research-progress-on-the-effects-of-the-tensile-strain-stimulation-on-proliferation-differention-and-pericellular-matrix-of-cartilage
#17
REVIEW
Ya-Xun Men, Yong-Liang Zhao, Xiang-Yun Cheng, Wan-Quan Cao, Gang Wang, Zi-Quan Yang
Mechanical stimulation widely exists in the body and participates in adjusting biological behavior of many kinds of cells. As a common stress pattern in the body, the tensile strain widely exists in many organs, such as bone and cartilage, muscle tendon, cardiac and pulmonary vessels, and so on. In recent years, with the development of the researches of biomechanics, a variety of mechanical loading devices, which are used to simulate the complex mechanical stimulation in the body to provide the tensile strain including the isometric, uniaxial and various types of mechanical waveform, came into being...
July 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29418119/leg-muscle-architecture-in-primates-and-its-correlation-with-locomotion-patterns
#18
Damiano Marchi, Carissa L Leischner, Francisco Pastor, Adam Hartstone-Rose
Bone biomechanical studies indicate that leg bone structure can be related to different locomotor patterns. The osteological correlates of extant primates' locomotion patterns and substrate use are important to consider when estimating corresponding behaviors of extinct primates. Here, we test if these same patterns are seen in the differences in leg muscular architecture. Muscle mass, fascicle lengths (FL), physiological cross-sectional area (PCSA), reduced PCSA (RPCSA) and tendon-to-muscle belly ratio were studied in 33 primate species (6 strepsirrhines, 14 platyrrhines and 13 catarrhines)...
March 2018: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/29417158/operative-treatment-algorithm-for-foot-deformities-in-charcot-marie-tooth-disease
#19
REVIEW
J W K Louwerens
The present article presents a short summary concerning the pathomechanisms and clinical presentation of foot deformities in Charcot-Marie-Tooth syndrome. Furthermore, a classification system is introduced and based on a recently performed review of the literature an operative treatment algorithm is provided. The operative technique of the following surgical procedures is described in more detail: 1. dorsiflexion osteotomy at the base of the 1st metatarsus, 2. dorsiflexion osteotomy at the base of a lesser metatarsal bone, 3...
February 7, 2018: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/29416028/inhibition-of-overactive-tgf-%C3%AE-attenuates-progression-of-heterotopic-ossification-in-mice
#20
Xiao Wang, Fengfeng Li, Liang Xie, Janet Crane, Gehua Zhen, Yuji Mishina, Ruoxian Deng, Bo Gao, Hao Chen, Shen Liu, Ping Yang, Manman Gao, Manli Tu, Yiguo Wang, Mei Wan, Cunyi Fan, Xu Cao
Acquired heterotopic ossification (HO) is a painful and debilitating disease characterized by extraskeletal bone formation after injury. The exact pathogenesis of HO remains unknown. Here we show that TGF-β initiates and promotes HO in mice. We find that calcified cartilage and newly formed bone resorb osteoclasts after onset of HO, which leads to high levels of active TGF-β that recruit mesenchymal stromal/progenitor cells (MSPCs) in the HO microenvironment. Transgenic expression of active TGF-β in tendon induces spontaneous HO, whereas systemic injection of a TGF-β neutralizing antibody attenuates ectopic bone formation in traumatic and BMP-induced mouse HO models, and in a fibrodysplasia ossificans progressive mouse model...
February 7, 2018: Nature Communications
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