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https://www.readbyqxmd.com/read/28340459/transcriptional-profiling-of-porcine-granulosa-cells-exposed-to-2-3-7-8-tetrachlorodibenzo-p-dioxin
#1
Agnieszka Sadowska, Anna Nynca, Monika Ruszkowska, Lukasz Paukszto, Kamil Myszczynski, Karina Orlowska, Sylwia Swigonska, Tomasz Molcan, Jan P Jastrzebski, Renata E Ciereszko
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a toxic man-made chemical compound contaminating the environment. An exposure of living organisms to TCDD may result in numerous disorders, including reproductive pathologies. The aim of the current study was to examine the effects of TCDD on the transcriptome of porcine granulosa cell line AVG-16. By employing next-generation sequencing (NGS) we aimed to identify genes potentially involved in the mechanism of TCDD action and toxicity in porcine granulosa cells...
March 16, 2017: Chemosphere
https://www.readbyqxmd.com/read/28333347/polymyxin-resistant-carbapenem-resistant-acinetobacter-baumannii-is-eradicated-by-a-triple-combination-of-agents-that-lack-individual-activity
#2
Justin R Lenhard, Visanu Thamlikitkul, Fernanda P Silveira, Samira M Garonzik, Xun Tao, Alan Forrest, Beom Soo Shin, Keith S Kaye, Jürgen B Bulitta, Roger L Nation, Jian Li, Brian T Tsuji
Objectives: The emergence of polymyxin resistance threatens to leave clinicians with few options for combatting drug-resistant Acinetobacter baumannii . The objectives of the current investigation were to define the in vitro emergence of polymyxin resistance and identify a combination regimen capable of eradicating A. baumannii with no apparent drug susceptibilities. Methods: Two clonally related, paired, A. baumannii isolates collected from a critically ill patient who developed colistin resistance while receiving colistin methanesulfonate in a clinical population pharmacokinetic study were evaluated: an A...
February 28, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28330437/long-term-outcomes-of-fistula-first-initiative-in-an-urban-university-hospital-is-it-still-relevant
#3
Jacques Greenberg, Senthil Jayarajan, Sridhar Reddy, Frank A Schmieder, Andrew B Roberts, Paul S van Bemmelen, Jean Lee, Eric T Choi
PURPOSE: Dialysis access failure is a major cause of morbidity in patients with end-stage renal disease. The Fistula First Breakthrough Initiative (FFBI) dictates arteriovenous fistulae (AVFs) should be preferred over arteriovenous grafts (AVGs) as first line for surgically placed accesses. The purpose of this study was to compare patency rates of surgical dialysis accesses in our mature, urban population after the FFBI. METHODS: Current dialysis patients with accesses placed between 2006 and 2011 were included...
April 2017: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28329100/long-term-cardiovascular-changes-following-creation-of-arteriovenous-fistula-in-patients-with-end-stage-renal-disease
#4
Yogesh N V Reddy, Masaru Obokata, Patrick G Dean, Vojtech Melenovsky, Karl A Nath, Barry A Borlaug
Aims: Short-term studies have reported left ventricular (LV) dilatation following surgical creation of arteriovenous fistulas (AVF) or arteriovenous grafts (AVGs), but chronic cardiac structural and functional changes have not been examined or related to clinical outcomes following AVF/AVG. We sought to characterize the long-term changes in cardiac structure and function in patients undergoing shunt creation for haemodialysis. Methods and results: A retrospective analysis was performed of patients undergoing echocardiography before and after surgical AVF/AVG creation for the initiation of haemodialysis...
March 6, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28326764/on-the-utility-of-higher-harmonics-in-electrospray-ionization-fourier-transform-electrostatic-linear-ion-trap-mass-spectrometry
#5
Eric T Dziekonski, Joshua T Johnson, Scott A McLuckey
The mass resolution (M/ΔM FWHM) is observed to linearly increase with harmonic order in a Fourier transform electrostatic linear ion trap mass spectrometer (FT-ELIT-MS). This behavior was predicted by Grosshans and Marshall for frequency-multiple detection in a Fourier transform ion cyclotron resonance mass spectrometer (FT-ICR-MS) only for situations when the prominent mechanism for signal decay is ion ejection from the trap. As the analyzer pressure in our ELIT chamber is relatively high, such that collisional scattering and collision-induced dissociation are expected to underlie much of the ion loss, we sought to explore the relationship between harmonic order and mass resolution...
March 22, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28297048/upper-arm-hemodialysis-access-in-sweden
#6
Ulf Hedin, Gunilla Welander
AIM: To provide the contemporary use of upper-arm access for hemodialysis in Sweden using data from a unique national registry for hemodialysis access. METHODS: Data were retrieved from a nation-wide registry for dialysis access in Sweden, Dialysis Access Database (DiAD) on the use and function of specific access types with a focus on upper-arm accesses. RESULTS: The data demonstrate an increased use of upper-arm access, likely dependent on a changing patient population, with brachiocephalic arteriovenous fistula (AVF) as the most common access type...
March 6, 2017: Journal of Vascular Access
https://www.readbyqxmd.com/read/28295984/safety-of-arteriovenous-fistulae-and-grafts-for-continuous-renal-replacement-therapy-the-michigan-experience
#7
Anas Al Rifai, Nidhi Sukul, Robert Wonnacott, Michael Heung
INTRODUCTION: Arteriovenous fistula or graft (AVF/AVG) use is widely considered contraindicated for continuous renal replacement therapy (CRRT), yet insertion of hemodialysis (HD) catheters can carry high complication risk in critically ill end-stage renal disease (ESRD) patients. METHODS: Single-center analysis of 48 consecutive hospitalized ESRD patients on maintenance HD who underwent CRRT using AVF/AVG from 2012 to 2013. Primary outcome was access-related complications...
March 13, 2017: Hemodialysis International
https://www.readbyqxmd.com/read/28293849/inhibitors-of-ethylene-biosynthesis-and-signaling
#8
G Eric Schaller, Brad M Binder
Ethylene is a gas biosynthesized by plants which has many physiological and developmental effects on their growth. Ethylene affects agriculturally and horticulturally important traits such as fruit ripening, post-harvest physiology, senescence, and abscission, and so ethylene action is often inhibited to improve the shelf life of fruits, vegetables, and cut flowers. Chemical inhibitors of ethylene action are also useful for research to characterize the mechanisms of ethylene biosynthesis and signal transduction, and the role that ethylene plays in various physiological processes...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28287047/how-nursing-home-residents-with-dementia-respond-to-the-interactive-art-installation-venster-a-pilot-study
#9
Tom Luyten, Susy Braun, Gaston Jamin, Susan van Hooren, Luc de Witte
The goal of this study was (1) to determine whether and how nursing home residents with dementia respond to the interactive art installation in general and (2) to identify whether responses change when the content type and, therefore, the nature of the interaction with the artwork changes. The interactive art installation 'VENSTER' evokes responses in nursing home residents with dementia, illustrating the potential of interactive artworks in the nursing home environment. Frequently observed responses were naming, recognizing or asking questions about depicted content and how the installation worked, physically gesturing towards or tapping on the screen and tapping or singing along to the music...
March 12, 2017: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/28285886/one-year-record-of-bioaerosols-and-particles-concentration-in-indo-gangetic-plain-implications-of-biomass-burning-emissions-to-high-level-of-endotoxin-exposure
#10
Prashant Rajput, Manzar Hussain Anjum, Tarun Gupta
Previous studies worldwide have suggested the potential role of bioaerosols as ice-nuclei and cloud-condensation nuclei. Furthermore, their participation in regulating the global carbon cycle urges systematic studies from different environmental conditions throughout the globe. Towards this through one-year study, conducted from June 2015-May 2016, we report on atmospheric abundance and variability of viable bioaerosols, organic carbon (OC) and particles number and deduced mass concentrations from Indo-Gangetic Plain (IGP; at Kanpur)...
March 9, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28283681/gene-expression-analyses-in-tomato-near-isogenic-lines-provide-evidence-for-ethylene-and-abscisic-acid-biosynthesis-fine-tuning-during-arbuscular-mycorrhiza-development
#11
Giselle Gomes Monteiro Fracetto, Lázaro Eustáquio Pereira Peres, Marcio Rodrigues Lambais
Plant responses to the environment and microorganisms, including arbuscular mycorrhizal fungi, involve complex hormonal interactions. It is known that abscisic acid (ABA) and ethylene may be involved in the regulation of arbuscular mycorrhiza (AM) and that part of the detrimental effects of ABA deficiency in plants is due to ethylene overproduction. In this study, we aimed to determine whether the low susceptibility to mycorrhizal colonization in ABA-deficient mutants is due to high levels of ethylene and whether AM development is associated with changes in the steady-state levels of transcripts of genes involved in the biosynthesis of ethylene and ABA...
March 11, 2017: Archives of Microbiology
https://www.readbyqxmd.com/read/28276987/the-use-of-continuous-vs-intermittent-cold-water-immersion-as-a-recovery-method-in-basketball-players-after-training-a-randomized-controlled-trial
#12
Braulio Sánchez-Ureña, Ismael Martínez-Guardado, Carmen Crespo, Rafael Timón, Julio Calleja-González, Sergio J Ibañez, Guillermo Olcina
OBJECTIVES: The main objective of this study was to compare two cold water immersion protocols, continuous or intermittent, on recovery in basketball players. METHODS: Ten male basketball players (age: 14 ± 0.4 years, body mass: 65.4 ± 9.1 kg, height: 175 ± 7.3 cm, body fat %: 10.3 ± 4) were included in the study. After three 90-minute training sessions (avg. heart rate 158 ± 11.92, 156 ± 7.06 and 151 ± 10.44 bpm), participants were grouped into a continuous immersion (12 min at 12 ± 0...
March 1, 2017: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/28271274/split-bolus-ct-urogram-is-less-more
#13
Hiram Shaish, Jeffrey H Newhouse
PURPOSE: To determine the accuracy of split-bolus CT urogram (SB-CTU) without special maneuvers for ureteral distention in diagnosing upper urinary tract urothelial carcinoma (UCA). MATERIALS AND METHODS: A hospital database was searched from 1/1/10, to 9/1/15, for SB-CTU exams without special maneuvers for ureteral distention. Accuracy of SB-CTU for detecting upper and lower urinary tract UCA was computed by comparing the prospective radiology report with cystoscopy, ureteroscopy, and/or urologic clinical follow-up...
March 7, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28266527/ethylene-induced-transcriptional-and-hormonal-responses-at-the-onset-of-sugarcane-ripening
#14
Camila P Cunha, Guilherme G Roberto, Renato Vicentini, Carolina G Lembke, Glaucia M Souza, Rafael V Ribeiro, Eduardo C Machado, Ana M M A Lagôa, Marcelo Menossi
The effects of ethephon as a sugarcane ripener are attributed to ethylene. However, the role of this phytohormone at the molecular level is unknown. We performed a transcriptome analysis combined with the evaluation of sucrose metabolism and hormone profiling of sugarcane plants sprayed with ethephon or aminoethoxyvinylglycine (AVG), an ethylene inhibitor, at the onset of ripening. The differential response between ethephon and AVG on sucrose level and sucrose synthase activity in internodes indicates ethylene as a potential regulator of sink strength...
March 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28250291/the-type-of-vascular-access-and-the-incidence-of-mortality-in-japanese-dialysis-patients
#15
Toshikazu Ozeki, Hideaki Shimizu, Yoshiro Fujita, Daijo Inaguma, Shoichi Maruyama, Yukako Ohyama, Shun Minatoguchi, Yukari Murai, Maho Terashita, Tomoki Tagaya
Objective The National Kidney Foundation (NKF) Kidney Disease Outcome Quality Initiative (KDOQI) guidelines have recommended the use of arteriovenous fistula (AVF) at the initiation of dialysis. However, there are significant differences in the dialysis environments of Japan and the United States, and there are few people who receive hemodialysis via a central venous catheter (CVC) in Japan. The aim of the present study was to examine the association between the type of vascular access at the initiation of dialysis and the incidence of mortality in Japan...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28245274/visual-steady-state-in-relation-to-age-and-cognitive-function
#16
Anna Horwitz, Mia Dyhr Thomsen, Iris Wiegand, Henrik Horwitz, Marc Klemp, Miki Nikolic, Lene Rask, Martin Lauritzen, Krisztina Benedek
Neocortical gamma activity is crucial for sensory perception and cognition. This study examines the value of using non-task stimulation-induced EEG oscillations to predict cognitive status in a birth cohort of healthy Danish males (Metropolit) with varying cognitive ability. In particular, we examine the steady-state VEP power response (SSVEP-PR) in the alpha (8Hz) and gamma (36Hz) bands in 54 males (avg. age: 62.0 years) and compare these with 10 young healthy participants (avg. age 27.6 years). Furthermore, we correlate the individual alpha-to-gamma difference in relative visual-area power (ΔRV) with cognitive scores for the older adults...
2017: PloS One
https://www.readbyqxmd.com/read/28240802/impact-of-pay-for-performance-on-access-at-first-dialysis-in-queensland
#17
Jennie Haarsager, Rathika Krishnasamy, Nicholas A Gray
AIM: Commencement of haemodialysis with an arteriovenous fistula (AVF) or arteriovenous graft (AVG) is associated with improved survival compared with commencement with a central venous catheter. In 2011-12, Queensland Health made incentive payments to renal units for early referred patients who commenced peritoneal dialysis (PD), or haemodialysis with an AVF/AVG. The aim of this study was to determine if pay-for-performance improved clinical care. METHODS: All patients who commenced dialysis in Australia between 2009 and 2014 and were registered with the Australia and New Zealand Dialysis and Transplant Registry (ANZDATA) were included...
February 27, 2017: Nephrology
https://www.readbyqxmd.com/read/28238919/characteristics-management-and-outcomes-of-surgically-treated-arteriovenous-fistula-aneurysm-in-patients-on-regular-hemodialysis
#18
Hassan Al-Thani, Ayman El-Menyar, Noora Al-Thani, Mohammad Asim, Ahmed Hussein, Ahmed Sadek, Ahmed Sharaf, Amr Fares
BACKGROUND: To investigate the clinical characteristics, surgical interventions and outcomes of arteriovenous fistula (AVF) aneurysms, we retrospectively analyzed patients on regular hemodialysis (HD). METHODS: We conducted a cohort study of all patients with HD access who presented with AVF aneurysms and underwent operative procedures over a 11-year period. Patients' demographics, comorbidities, vascular access characteristics, management of aneurysms, complications and outcomes were analyzed...
February 23, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28237076/metal-concentration-in-the-tourist-beaches-of-south-durban-an-industrial-hub-of-south-africa
#19
E Vetrimurugan, V C Shruti, M P Jonathan, Priyadarsi D Roy, N W Kunene, Lorena Elizabeth Campos Villegas
South Durban basin of South Africa has witnessed tremendous urban, industrial expansion and mass tourism impacts exerting significant pressure over marine environments. 43 sediment samples from 7 different beaches (Bluff beach; Ansteys beach; Brighton beach; Cutting beach; Isipingo beach; Tiger Rocks beach; Amanzimtoti beach) were analyzed for acid leachable metals (ALMs) Fe, Mg, Mn, Cr, Cu, Mo, Ni, Co, Pb, Cd, Zn and Hg. The metal concentrations found in all the beaches were higher than the background reference values (avg...
February 22, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28222990/establishing-patient-specific-criteria-for-selecting-the-optimal-upper-extremity-vascular-access-procedure
#20
Karen Woo, Jesus Ulloa, Michael Allon, Christopher G Carsten, Eric S Chemla, Mitchell L Henry, Thomas S Huber, Jeffrey H Lawson, Charmaine E Lok, Eric K Peden, Larry Scher, Anton Sidawy, Melinda Maggard-Gibbons, David Cull
OBJECTIVE: The Kidney Disease Outcome Quality Initiative and Fistula First Breakthrough Initiative call for the indiscriminate creation of arteriovenous fistulas (AVFs) over arteriovenous grafts (AVGs) without providing patient-specific criteria for vascular access selection. Although the U.S. AVF rate has increased dramatically, several reports have found that this singular focus on increasing AVFs has resulted in increased AVF nonmaturation/early failure and a high prevalence of catheter dependence...
April 2017: Journal of Vascular Surgery
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