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https://www.readbyqxmd.com/read/28647882/leaching-of-phthalate-esters-from-different-drinking-stuffs-and-their-subsequent-biodegradation
#1
Muhammad Ali Surhio, Farah N Talpur, Shafi M Nizamani, Marvi Kanwal Talpur, Hassan Imran Afridi, Abid Ali Khaskheli, Shazia Bhurgri, Junaid Ali Surhio
Phthalate esters (PAEs) are mainly used as plasticizers, and their release in the environment during the manufacturing, use, and disposal has caused serious environmental health concerns, since some of them are suspected to be mutagens, hepatotoxic agents, and carcinogens. In the present study, leaching of PAEs from different drinking stuffs (water cooler, mineral water bottles) exposed to sunlight and baby feeders subjected to different heating treatments (boiling, autoclave and oven) was studied. Results showed that a total of 10 PAEs were leached and identified...
June 25, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28647536/crhr1-exacerbates-the-glial-inflammatory-response-and-alters-bdnf-trkb-pcreb-signaling-in-a-rat-model-of-global-cerebral-ischemia-implications-for-neuroprotection-and-cognitive-recovery
#2
Patricia B de la Tremblaye, Simon M Benoit, Sarah Schock, Hélène Plamondon
This study examined the impact of corticotropin-releasing hormone type 1 receptor (CRHR1) blockade using Antalarmin (ANT) on the expression of markers of neuroplasticity and inflammation, as well as neuroprotection and behavioral recovery following global cerebral ischemia. Male Wistar rats (N=50) were treated with ANT (2μg/2μl; icv) or a vehicle solution prior to a sham or four vessel (4VO) occlusion. Seven days post ischemia, anxiety was assessed in the Elevated Plus Maze and Open Field tests, and fear and spatial learning in a Y-Maze Passive Avoidance Task and the Barnes Maze...
June 21, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28647409/a-residue-specific-insight-into-the-arkadia-e3-ubiquitin-ligase-activity-and-conformational-plasticity
#3
Maria Birkou, Christos T Chasapis, Konstantinos D Marousis, Ariadni K Loutsidou, Detlef Bentrop, Moreno Lelli, Torsten Herrmann, Jonathon M Carthy, Vasso Episkopou, Georgios A Spyroulias
Arkadia (Rnf111) is an E3 Ubiquitin ligase that plays a central role in the amplification of TGF-β signaling responses by targeting for degradation the negative regulators of the pathway, Smad6 and Smad7 and the nuclear co-repressors Ski and Skil (SnoN). Arkadia's function in vivo depends on the RING-H2 interaction with the E2 enzyme UbcH5b in order to ligate ubiquitin chains on its substrates. A conserved tryptophan (W972) in the C-terminal α-helix is widely accepted as essential for E2 recruitment and interaction and thus also for E3 enzymatic activity...
June 21, 2017: Journal of Molecular Biology
https://www.readbyqxmd.com/read/28647183/activity-of-tagetes-minuta-linnaeus-asteraceae-essential-oil-against-l3-anisakis-larvae-type-1
#4
Filippo Giarratana, Daniele Muscolino, Graziella Ziino, Alessandro Giuffrida, Stefania Maria Marotta, Vittorio Lo Presti, Vincenzo Chiofalo, Antonio Panebianco
OBJECTIVE: To evaluate in vitro effects of Tagetes minuta L. essential oil (TEO) on L3 Anisakis larvae type 1. METHODS: In order to evaluate the potential use of Tagetes minuta essential oil against L3 Anisakis larvae three different media were tested: 1) a saline solution (SS); 2) an industrial marinating solution (MS); 3) sunflower seeds oil (SO). For each media and concentrations of TEO (0.1%, 0.5%, 1.0% and 5.0% v/v), 20 parasites were introduced into plastic Petri dishes (diameter 90 mm) and maintained at room temperature...
May 2017: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28646780/sem-eds-and-optical-microscopy-analyses-of-microplastics-in-ocean-trawl-and-fish-guts
#5
Zhong-Min Wang, Jeff Wagner, Sutapa Ghosal, Gagandeep Bedi, Stephen Wall
Microplastic particles from Atlantic and Pacific Ocean trawls, lab-fed fish guts and ocean fish guts have been characterized using optical microscopy and SEM/EDS in terms of size, morphology, and chemistry. We assessed whether these measurements could serve as a rapid screening process for subsequent identification of the likely microplastic candidates by micro-spectroscopy. Optical microscopy enabled morphological classification of the types of particles or fibers present in the sample, as well as the quantification of particle size ranges and fiber lengths...
June 21, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28646683/fabrication-of-low-fire-hazard-flexible-poly-vinyl-chloride-via-reutilization-of-heavy-metal-biosorbents
#6
Ye-Tang Pan, De-Yi Wang
As a naturally abundant biopolymer, chitosan is considered to be a suitable adsorbent for stannate (SnO3(2-)) in tin plating wastewater. However, mass transfer of the adsorbent and its recycling remain challenging problems. Though flexible poly(vinyl chloride) (PVC) is highly flammable due to the addition of plasticizers, the traditional flame retardant, antimony trioxide (Sb2O3), is potentially harmful. In this study, chitosan was anchored onto the surface of PVC resin to adsorb SnO3(2-) from wastewater. Thereafter, tin-doped chitosan-coated PVC resin was readily recycled and processed into a flexible PVC composite (modified fPVC)...
June 15, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28646625/fluctuating-effects-of-genetic-and-plastic-changes-in-body-mass-on-population-dynamics-in-a-large-herbivore
#7
Gabriel Pigeon, Thomas H G Ezard, Marco Festa-Bianchet, David W Coltman, Fanie Pelletier
Recent studies suggest that evolutionary changes can occur on a contemporary time scale. Hence, evolution can influence ecology and vice-versa. To understand the importance of eco-evolutionary dynamics in population dynamics, we must quantify the relative contribution of ecological and evolutionary changes to population growth and other ecological processes. To date, however, most eco-evolutionary dynamics studies have not partitioned the relative contribution of plastic and evolutionary changes in traits on population, community and ecosystem processes...
June 24, 2017: Ecology
https://www.readbyqxmd.com/read/28646556/injury-induced-maladaption-and-dysregulation-of-calcium-channel-alpha-2-delta-subunit-proteins-and-its-contribution-to-neuropathic-pain-development
#8
REVIEW
Nian Gong, John Park, Z David Luo
Voltage gated calcium channels (VGCCs) play important roles in physiological functions including modulations of neurotransmitter release, neuronal network activities, intracellular signaling pathways, and gene expression. Some pathological conditions, including nerve injuries, can cause dysregulation of VGCCs and their subunits. This in turn can lead to functional maladaption of VGCCs and their subunits, which can contribute to development of disorders such as pain sensations. This review summarized recent findings related to maladaptive changes of dysregulated VGCC alpha-2-delta-1 subunit (Cav α2 δ1 ) with a focus on exploration of mechanisms underlying contribution of Cav α2 δ1 to pain signal transduction...
June 23, 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/28646336/nogo-a-antibodies-enhance-axonal-repair-and-remyelination-in-neuro-inflammatory-and-demyelinating-pathology
#9
Benjamin V Ineichen, Sandra Kapitza, Christiane Bleul, Nicolas Good, Patricia S Plattner, Maryam S Seyedsadr, Julia Kaiser, Marc P Schneider, Björn Zörner, Roland Martin, Michael Linnebank, Martin E Schwab
Two hallmarks of chronic multiple sclerosis lesions are the absence of significant spontaneous remyelination and primary as well as secondary neurodegeneration. Both characteristics may be influenced by the presence of inhibitory factors preventing myelin and neuronal repair. We investigated the potential of antibodies against Nogo-A, a well-known inhibitory protein for neuronal growth and plasticity, to enhance neuronal regeneration and remyelination in two animal models of multiple sclerosis. We induced a targeted experimental autoimmune encephalomyelitis (EAE) lesion in the dorsal funiculus of the cervical spinal cord of adult rats resulting in a large drop of skilled forelimb motor functions...
June 23, 2017: Acta Neuropathologica
https://www.readbyqxmd.com/read/28646317/di-n-butyl-phthalate-prompts-interruption-of-spermatogenesis-steroidogenesis-and-fertility-associated-with-increased-testicular-oxidative-stress-in-adult-male-rats
#10
Giribabu Nelli, Sreenivasula Reddy Pamanji
Di-n-butyl phthalate (DBP) is extensively used as plasticizer, and it was ubiquitary released into the environment. The present study was aimed to investigate the effect of DBP on reproductive competence in adult male rats. Adult male rats were received corn oil or DBP injection intraperitoneally (ip) at 100 and 500 mg/kg body weight on 90, 97, 104, and 111 days. Following completion of the experimental period, adult male rats were cohabitated with untreated proestrus female rats for determination of fertilization capacity...
June 24, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28646147/whole-organ-vascular-casting-and-microct-examination-of-the-human-placental-vascular-tree-reveals-novel-alterations-associated-with-pregnancy-disease
#11
Toluwalope O Junaid, Robert S Bradley, Rohan M Lewis, John D Aplin, Edward D Johnstone
Experimental methods that allow examination of the intact vascular network of large organs, such as the human placenta are limited, preventing adequate comparison of normal and abnormal vascular development in pregnancy disease. Our aims were (i) to devise an effective technique for three-dimensional analyses of human placental vessels; (ii) demonstrate the utility of the technique in the comparison of placental vessel networks in normal and fetal growth restriction (FGR) complicated pregnancies. Radiopaque plastic vessel networks of normal and FGR placentas (n = 12/group) were created by filling the vessels with resin and corroding the surrounding tissues...
June 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28646012/scatter-correction-with-combined-single-scatter-simulation-and-monte-carlo-simulation-scaling-improved-the-visual-artifacts-and-quantification-in-3d-brain-pet-ct-imaging-with-15-o-gas-inhalation
#12
Keiichi Magota, Tohru Shiga, Yukari Asano, Daiki Shinyama, Jinghan Ye, Amy E Perkins, Piotr J Maniawski, Takuya Toyonaga, Kentaro Kobayashi, Kenji Hirata, Chietsugu Katoh, Naoya Hattori, Nagara Tamaki
In three-dimensional positron emission tomography (PET)/computed tomography (CT) imaging of the brain with (15)O-gas inhalation, high radioactivity in the face mask creates cold artifacts and affects the quantitative accuracy when scatters is corrected by conventional methods (e.g., single-scatter simulation [SSS] with tail-fitting scaling [TFS-SSS]). Here we examined the validity of a newly developed scatter correction method that combines SSS with a scaling factor calculated by Monte Carlo simulation (MCS-SSS)...
June 23, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28645761/beach-macro-litter-monitoring-and-floating-microplastic-in-a-coastal-area-of-indonesia
#13
Agung Dhamar Syakti, Rafika Bouhroum, Nuning Vita Hidayati, Chandra Joei Koenawan, Abdelaziz Boulkamh, Isdy Sulistyo, Stephanie Lebarillier, Syafsir Akhlus, Pierre Doumenq, Pascal Wong-Wah-Chung
Qualitative analysis of the structures of the polymers composing floating plastic debris was performed using attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR), and the aging of the debris was assessed by measuring carbonyl group formation on the particle surfaces. Plastic material made up >75% of the 2313 items collected during a three-year survey. The size, shape and color of the microplastic were correlated with the polymer structure. The most abundant plastic materials were polypropylene (68%) and low-density polyethylene (11%), and the predominant colors of the plastics were white, blue and green...
June 20, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28645759/microplastics-in-the-sediments-of-terra-nova-bay-ross-sea-antarctica
#14
Cristina Munari, Vanessa Infantini, Marco Scoponi, Eugenio Rastelli, Cinzia Corinaldesi, Michele Mistri
This is the first survey to investigate the occurrence and extent of plastic contamination in sediments collected in Terra Nova Bay (Ross Sea, Antarctica). Plastic debris extracted from 31 samples of sediments were counted, weighted and identified by Fourier-transform infrared spectroscopy (FT-IR). All sediment samples contained plastics: a total of 1661 items of debris (3.14g) were recorded from the 31 samples of sediment. Plastic particles in the samples ranged from 0.3 to 22mm in length. Fibres were the most frequent type of small plastics debris detected...
June 20, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28645679/percutaneous-management-of-benign-biliary-disorders-in-children
#15
G Kahriman, N Ozcan, S B Gorkem
PURPOSE: The goal of this study was to analyze the outcomes of percutaneous transhepatic management of benign biliary disorders in pediatric patients. MATERIALS AND METHODS: This study included 11 pediatric patients who underwent percutaneous transhepatic biliary interventional procedures between September 2007 and December 2016. There were 3 males and 8 females with a mean age of 9.6±5.4 (SD)years (range: 2-17years). Technical details, complications and outcome of the procedures were evaluated...
June 20, 2017: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/28645383/importance-of-the-immune-system-in-mediating-plasticity-of-the-brain-and-behavior
#16
EDITORIAL
Li Tian, Marie-Eve Tremblay
No abstract text is available yet for this article.
October 3, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28645321/genome-wide-analysis-of-dna-methylation-in-hypothalamus-and-ovary-of-capra-hircus
#17
Stefano Frattini, Emanuele Capra, Barbara Lazzari, Stephanie D McKay, Beatrice Coizet, Andrea Talenti, Debora Groppetti, Pietro Riccaboni, Alessandro Pecile, Stefania Chessa, Bianca Castiglioni, John L Williams, Giulio Pagnacco, Alessandra Stella, Paola Crepaldi
BACKGROUND: DNA methylation is a frequently studied epigenetic modification due to its role in regulating gene expression and hence in biological processes and in determining phenotypic plasticity in organisms. Rudimentary DNA methylation patterns for some livestock species are publically available: among these, goat methylome deserves to be further explored. RESULTS: Genome-wide DNA methylation maps of the hypothalamus and ovary from Saanen goats were generated using Methyl-CpG binding domain protein sequencing (MBD-seq)...
June 23, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28645300/bacterial-ghosts-as-adjuvants-mechanisms-and-potential
#18
REVIEW
Irshad A Hajam, Pervaiz A Dar, Gayeon Won, John Hwa Lee
Bacterial ghosts (BG) are empty cell envelopes derived from Gram-negative bacteria. They contain many innate immunostimulatory agonists, and are potent activators of a broad range of cell types involved in innate and adaptive immunity. Several considerable studies have demonstrated the effectiveness of BG as adjuvants as well as their ability to induce proinflammatory cytokine production by a range of immune and non-immune cell types. These proinflammatory cytokines trigger a generalized recruitment of T and B lymphocytes to lymph nodes that maximize the chances of encounter with their cognate antigen, and subsequent elicitation of potent immune responses...
June 24, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28645186/igf-i-gene-therapy-in-aging-rats-modulates-hippocampal-genes-relevant-to-memory-function
#19
Joaquín Pardo, Martin C Abba, Ezequiel Lacunza, Olalekan M Ogundele, Isabel Paiva, Gustavo R Morel, Tiago F Outeiro, Rodolfo G Goya
In rats, learning and memory performance decline during normal aging, which makes this rodent species a suitable model to evaluate therapeutic strategies. In aging rats, insulin-like growth factor-I (IGF-I), is known to significantly improve spatial memory accuracy as compared to control counterparts. A constellation of gene expression changes underlie the hippocampal phenotype of aging but no studies on the effects of IGF-I on the hippocampal transcriptome of old rodents have been documented. Here, we assessed the effects of IGF-I gene therapy on spatial memory performance in old female rats and compared them with changes in the hippocampal transcriptome...
June 22, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28645086/toddler-exposure-to-flame-retardant-chemicals-magnitude-health-concern-and-potential-risk-or-protective-factors-of-exposure-observational-studies-summarized-in-a-systematic-review
#20
REVIEW
Eva J Sugeng, Marijke de Cock, Linda J Schoonmade, Margot van de Bor
Endocrine disrupting flame retardant (FR) chemicals form a human health concern, that is investigated mostly from the perspective of adult- and early life exposure. No overview of studies on toddler exposure and health effects exist. However, toddlerhood is a critical developmental period and toddlers are at increased risk for exposure because of their age-specific behavior. This systematic review encompasses toddler FR exposure studies in three countries, associated health effects and potential environmental, demographic, or behavioral risk- or protective factors for toddler exposure...
June 14, 2017: Chemosphere
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