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https://www.readbyqxmd.com/read/27896241/local-administration-of-tranexamic-acid-during-prostatectomy-surgery-effects-on-reducing-the-amount-of-bleeding
#1
Pejman Pourfakhr, Elham Gatavi, Shahram Gooran, Farhad Etezadi, Mohamad Reza Khajavi, Reza Pourroustaei, Reza Shariat Moharari, Atabak Najafi
BACKGROUND: One of the issues in prostatectomy surgery is bleeding. Although tranexamic acid (TRA) is an antifibrinolytic agent for reducing bleeding, controversies surround its use. OBJECTIVES: In this study, the effect of local administration of TRA on reducing bleeding during prostatectomy surgery was evaluated. METHODS: A total of 186 patients who underwent prostatectomy surgery were assessed in this clinical trial study. Patients were divided randomly into two groups...
November 2016: Nephro-urology Monthly
https://www.readbyqxmd.com/read/27873145/use-of-refrigerant-spray-of-a-propane-butane-isobutane-gas-mixture-in-the-management-of-keratocystic-odontogenic-tumors-a-preliminary-study
#2
Eduardo Luis de Souza Cruz, Ana Karla da Silva Tabosa, Aline Semblano Carreira Falcão, Talita Tartari, Lucas Machado de Menezes, Edmar Tavares da Costa, José Thiers Carneiro Júnior
PURPOSE: Keratocystic odontogenic tumor (KCOT) is an aggressive benign tumor and the management by complete enucleation followed by cryotherapy maintains the inorganic bone matrix, resulting in better repair and reduces the rates of recurrence. A refrigerant spray with a propane/butane/isobutane gas mixture has been pointed to as an alternative to liquid nitrogen, because the device is easy to handle and contain within the cavity, providing better control and lower risk of injury to the adjacent soft tissue...
November 21, 2016: Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27869357/the-impact-of-endoscopic-sinus-surgery-on-paranasal-physiology-in-simulated-sinus-cavities
#3
Ravi Jain, Haribalan Kumar, Merryn Tawhai, Richard Douglas
BACKGROUND: Surgery improves symptoms for the majority of chronic rhinosinusitis (CRS) patients; however, physiological changes in the sinus cavities remain poorly characterized. Direct measurement of changes in airflow, pressure, temperature, humidity, and intranasal spray distribution following surgery is technically challenging. Accordingly, we have used computational fluid dynamic modeling to quantify how these parameters change postoperatively. METHODS: Computed tomography images from a normal control, a patient with CRS preoperatively and postoperatively, and a patient following an endoscopic Lothrop procedure (ELP) were used to create 4 three-dimensional models of the sinus cavities...
November 21, 2016: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/27844212/a-first-in-human-randomized-controlled-subject-and-reviewer-blinded-multicenter-study-of-actamax%C3%A2-adhesion-barrier
#4
Geoffrey H Trew, George A Pistofidis, Sara Y Brucker, Bernhard Krämer, Nicole M Ziegler, Matthias Korell, Henning Ritter, Alex McConnachie, Ian Ford, Alison M Crowe, Trudy D Estridge, Michael P Diamond, Rudy L De Wilde
PURPOSE: Post-surgical adhesions remain a significant concern following abdominopelvic surgery. This study was to assess safety, manageability and explore preliminary efficacy of applying a degradable hydrogel adhesion barrier to areas of surgical trauma following gynecologic laparoscopic abdominopelvic surgery. METHODS: This first-in-human, prospective, randomized, multicenter, subject- and reviewer-blinded clinical study was conducted in 78 premenopausal women (18-46 years) wishing to maintain fertility and undergoing gynecologic laparoscopic abdominopelvic surgery with planned clinically indicated second-look laparoscopy (SLL) at 4-12 weeks...
November 14, 2016: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/27822702/effects-of-mobile-phone-wechat-services-improve-adherence-to-corticosteroid-nasal-spray-treatment-for-chronic-rhinosinusitis-after-functional-endoscopic-sinus-surgery-a-3-month-follow-up-study
#5
Shaoyan Feng, Zibin Liang, Rongkai Zhang, Wei Liao, Yuan Chen, Yunping Fan, Huabin Li
The objective of the study is to investigate the impact of receiving daily WeChat services on one's cell phone on adherence to corticosteroid nasal spray treatment in chronic rhinosinusitis (CRS) patients after functional endoscopic sinus surgery (FESS). This study was a two-arm, randomized, follow-up investigation. Patients with chronic rhinosinusitis with/without nasal polyps following bilateral FESS were randomised to receive, or to not receive, daily WeChat service on their cell phone to take corticosteroid nasal spray treatment...
November 7, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27812810/-local-fixation-of-antibiotics-by-fibrin-spray-in-bone-defects-with-soft-tissue-involvement
#6
Maren Janko, Christoph Nau, Ingo Marzi, Johannes Frank
In acute and chronic bone infections with concomitant soft tissue involvement the current gold standard is radical surgical debridement including explantation of the infected prosthetic devices. This is followed by initiation of systemic antibiotic therapy appropriate for the antibiogram. Several revision operations are often necessary to achieve complete healing. Additional treatment with local antibiotics or antibiotic-containing substances is routinely used in bone surgery. Apart from the typical procedures with commercially available products, we have conducted a study with 21 patients by application of local antibiotic treatment in combination with the fibrin glue spray technique and evaluated the results...
November 3, 2016: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/27720463/nasal-surgery-for-obstructive-sleep-apnea-syndrome
#7
Samuel A Mickelson
Obstructive sleep apnea is a common condition, primarily caused by narrowing of the nasal and pharyngeal airway. Treatment with continuous positive airway pressure (CPAP) is considered the first line of therapy, but long-term compliance is only about 40%, often because of nasal obstruction. Any nasal obstruction can worsen CPAP compliance. Treatment of the nasal obstruction with topical nasal steroid sprays or nasal dilators has been shown to improve sleep disordered breathing. Surgical treatment of nasal obstruction, has been shown to improve sleep disordered breathing, as well as CPAP requirement and compliance with CPAP...
October 6, 2016: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/27706120/effect-of-liposomes-vitamins-a-and-e-nasal-spray-in-reducing-the-healing-time-after-septoplasty-with-concurrent-turbinate-surgery-in-adolescents
#8
Filippo Ricciardiello, Elena Cantone, Teresa Abate, Antonella M Di Lullo, Flavia Oliva, Maurizio Iengo, Giuseppe De Bernardo
BACKGROUND: This study evaluates endoscopic and quality of life (QoL) outcomes in two groups, composed by both allergic (A) and non-allergic (N-A) adolescents undergoing septoplasty with concurrent turbinate surgery by radiofrequency treated after surgery with nasal spray containing liposomes and vitamins A and E. METHODS: This double-blind randomized study was carried out on 40 patients (22 males, 18 females, mean age 15.5 ± 1.0 years) undergoing septoplasty and volumetric tissue reduction of inferior turbinates by radiofrequency for post-traumatic deformities and severe nasal obstruction...
October 5, 2016: Minerva Pediatrica
https://www.readbyqxmd.com/read/27703606/in-vitro-histological-evaluation-of-the-surgical-margins-made-by-different-laser-wavelengths-in-tongue-tissues
#9
Ana-Salvaterra Azevedo, Luís-Silva Monteiro, Fernando Ferreira, Maria-Leonor Delgado, Fernanda Garcês, Sofia Carreira, Marco Martins, Juan Suarez-Quintanilla
BACKGROUND: Lasers have become standard tools for the surgical treatment of oral lesions. The purpose of this study is to determine the surgical margins and histologically evaluate the tissue thermal effects induced by different types of surgical instruments. MATERIAL AND METHODS: Cuts were made in pork tongues' mucosa with different lasers (Er:YAG at 2W with and without air / water spray and at 4W with and without air / water spray; CO2 at 3.5W and 7W in pulsed mode and at 7W in continuous mode; the diode laser at 3...
October 2016: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/27693571/better-defining-the-spectrum-of-adult-hypospadias-examining-the-effect-of-childhood-surgery-on-adult-presentation
#10
Nathan Y Hoy, Keith F Rourke
OBJECTIVES: To describe the spectrum of adult presentations with hypospadias-related complications and examine the effect of childhood surgical repair on these adult presentations. METHODS: A retrospective chart review over a 10-year period, from Aug. 2004-Dec. 2014, demonstrated 93 adult patients who presented to a reconstructive urologist with complications related to hypospadias. Patients were divided into two groups: those with no prior hypospadias surgery (Group 1, N=19) and those who underwent surgical correction as a child (Group 2, N=74)...
September 27, 2016: Urology
https://www.readbyqxmd.com/read/27684856/successful-treatment-of-cutaneous-squamous-cell-carcinoma-with-intralesional-cryosurgery-case-report
#11
Chaw-Ning Lee, Shin-Chen Pan, Julia Yu-Yun Lee, Tak-Wah Wong
BACKGROUND: Wide excision or Mohs surgery is the standard treatment of skin squamous cell carcinoma (SCC). Superficial SCC or tumor smaller than 1 cm has been treated successfully with open spray cryosurgery. Larger tumor may not be as effective because tissue destruction is usually superficial. Intralesional cryosurgery (IC) may provide a deeper and better cell killing effect in larger tumors. We investigated the safety and efficacy of treating nodular SCC in 4 patients with IC. METHODS: Four patients with nodular SCC/keratoacanthoma (tumor size, 1-2...
September 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27677684/surgical-treatment-oral-rehabilitation-and-orthognathic-surgery-after-failure-of-pharmacologic-treatment-of-central-giant-cell-lesion-a-case-report
#12
Renato Luiz Maia Nogueira, Rafael Lima Verde Osterne, Roberta Barroso Cavalcante, Ricardo Teixeira Abreu
Although pharmacologic treatments for central giant cell lesions have gained much emphasis, these treatment modalities do not always have successful outcomes, and surgical treatment may be necessary. The purpose of the present study was to report a case of aggressive central giant cell lesion initially treated by nonsurgical methods without satisfactory results, necessitating segmental mandibular resection for definitive treatment and oral rehabilitation. A 20-year-old woman was diagnosed with an aggressive central giant cell lesion in the mandible...
December 2016: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27632682/a-single-intravenous-dose-of-novel-flurbiprofen-loaded-proniosome-formulations-provides-prolonged-systemic-exposure-and-anti-inflammatory-effect
#13
Preeti Verma, Sunil Kumar Prajapati, Rajbharan Yadav, Danielle Senyschyn, Peter R Shea, Natalie L Trevaskis
Vesicular and colloidal delivery systems can be designed to control drug release spatially and temporally to improve drug efficacy and side effect profiles. Niosomes (vesicles prepared from nonionic surfactants in aqueous media) are gaining interest as an alternative vesicular delivery system as they offer advantages such as biocompatibility, chemical stability, low cost, high purity and versatility. However, the physical stability of niosomes, like other vesicular systems, is limited by vesicle fusion, aggregation and leakage...
September 15, 2016: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/27590462/vapocoolant-spray-versus-lidocaine-infiltration-for-radial-artery-cannulation-a-prospective-randomized-controlled-clinical-trial
#14
Dirk Rüsch, Tilo Koch, Florian Seel, Leopold Eberhart
OBJECTIVES: Local infiltration with lidocaine is a frequently used measure to prevent pain during arterial cannulation. Its administration is associated with pain. Vapocoolants like ethyl chloride or alkanes also affect rapid-onset anesthesia. However, their administration causes less discomfort compared with administration of lidocaine. The effectiveness of vapocoolants in mitigating discomfort associated with arterial cannulation never has been studied. The authors therefore compared vapocoolant with lidocaine for reducing discomfort caused by arterial cannulation...
June 8, 2016: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/27466853/delivery-of-topical-therapies
#15
Kristine A Smith, Luke Rudmik
Chronic rhinosinusitis with nasal polyposis (CRSwNP) is an inflammatory disease of the sinonasal passages. Similar to other chronic inflammatory diseases, an essential component of the long-term control is prolonged medical therapy. To minimize the risk of adverse effects and cumulative complications of systemic medications, topical sinonasal therapy has become the primary strategy for prolonged medical therapy. The objective of this review article is to describe the evidence for the most common topical sinonasal delivery techniques...
2016: Advances in Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27449354/historical-perspectives-of-the-american-association-for-thoracic-surgery-thomas-l-spray
#16
EDITORIAL
James S Tweddell
No abstract text is available yet for this article.
October 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27416546/effect-of-topical-furosemide-on-rhinosinusal-polyposis-relapse-after-endoscopic-sinus-surgery-a-randomized-clinical-trial
#17
Farnaz Hashemian, Mohammad Ali Ghorbanian, Farshad Hashemian, Seyed Alireza Mortazavi, Mojgan Sheikhi, Javaneh Jahanshahi, Jalal Poorolajal
Importance: Evidence from previous studies suggests that furosemide may be effective in reducing the recurrence of polyps after sinus surgery. However, the evidence is limited and insufficient, and further investigations are required. Objective: To assess the effect of topical furosemide on recurrence rate of rhinosinusal polyposis after endoscopic sinus surgery. Design, Setting, and Participants: Triple-blind randomized clinical trial of patients aged 18 to 60 years with chronic rhinosinusitis associated with polyposis who did not respond to medical treatment and were candidates for endoscopic sinus surgery at Besat Hospital, Hamadan University of Medical Sciences, from April 2014 to June 2015...
November 1, 2016: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/27389387/-clinical-trial-to-test-the-ifuse-implant-system%C3%A2-in-patients-with-sacroiliac-joint-syndrome-one-year-results
#18
R Bornemann, R Pflugmacher, M Webler, E M W Koch, J Dengler, D C Wirtz, S P Frey
Background: This study reports one year post-operative monitoring of the efficacy and safety of iFuse Implant System® in patients with sacroiliac joint syndrome. Material and Methods: After 6 months of inadequate conservative treatment, patients with properly proven ISG syndrome were selected for surgery. The iFuse implants had a triangular profile and coating of porous titanium plasma spray and were used in the minimally invasive procedures. The procedure was performed under general anaesthesia and fluoroscopic control...
July 7, 2016: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/27388077/emerging-infections-implications-for-dental-care
#19
N P Monaghan
Over the last 20 years the majority of emerging infections which have spread rapidly across the globe have been respiratory infections that are spread via droplets, a trend which is likely to continue. Aerosol spray generation in the dental surgery has the potential to spread such infections to staff or other patients. Although the diseases may differ, some common approaches can reduce the risk of transmission. Dental professionals should be aware of areas affected by emerging infections, the incubation period and the recent travel history of patients...
July 8, 2016: British Dental Journal
https://www.readbyqxmd.com/read/27353096/-prevention-of-intraoperative-incidental-injuries-during-sphincter-preserving-surgery-for-rectal-cancer-and-management-of-postoperative-complication
#20
Fanghai Han, Hongming Li
Prevention of intraoperative incidental injuries during radical operation for rectal cancer and management of postoperative complication are associated with successful operation and prognosis of patients. This paper discusses how to prevent such intraoperative incidental injuries and how to manage postoperative complication. (1) Accurate clinical evaluation should be performed before operation and reasonable treatment decision should be made, including determination of the distance from transection to lower margin of the tumor, T and M staging evaluated by MRI, fascia invasion of mesorectum, metastasis of lateral lymph nodes, metastatic station of mesentery lymph node, association between levator ani muscle and anal sphincter, course and length of sigmoid observed by Barium enema, length assessment of pull-through bowel...
June 2016: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
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