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https://www.readbyqxmd.com/read/29094889/chronic-rhinosinusitis
#1
Ahmad R Sedaghat
Chronic rhinosinusitis is an inflammatory disease of the paranasal sinuses that occurs in 1% to 5% of the U.S. POPULATION: It may significantly decrease quality of life. Chronic rhinosinusitis is defined by the presence of at least two out of four cardinal symptoms (i.e., facial pain/pressure, hyposmia/anosmia, nasal drainage, and nasal obstruction) for at least 12 consecutive weeks, in addition to objective evidence. Objective evidence of chronic rhinosinusitis may be obtained on physical examination (anterior rhinoscopy, endoscopy) or radiography, preferably from sinus computed tomography...
October 15, 2017: American Family Physician
https://www.readbyqxmd.com/read/29077183/safety-of-the-use-of-xylometazoline-nasal-spray-in-young-children-undergoing-lacrimal-surgery-an-observational-study
#2
Varajini Joganathan, Bijan Beigi
PURPOSE: It is common practice to prepare the nasal mucosa with decongestant in children undergoing lacrimal surgery. Xylometazoline 0.05% (Otrivine) nasal spray is commonly used. It has been reported to cause cardiovascular side effects. In the absence of formal guidelines on the safety of the use of nasal decongestants in children, we reviewed our practice to answer the question: How safe is preoperative use of xylometazoline in children undergoing lacrimal surgery? To our knowledge, this is the first study to address the potential side effects of the use of xylometazoline preoperatively in children undergoing lacrimal surgery...
October 24, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/29062824/comparative-study-of-topical-vs-intravenous-tranexamic-acid-regarding-blood-loss-in-total-knee-arthroplasty
#3
Ari Zekcer, Ricardo Del Priori, Clauber Tieppo, Ricardo Soares da Silva, Nilson Roberto Severino
OBJECTIVE: To compare topical vs. intravenous tranexamic acid (TA) in total knee arthroplasty regarding blood loss and transfusion. METHODS: Ninety patients were randomized to receive TA intravenously (20 mg/kg in 100 mL of saline; group IV), topically (1.5 g in 50 mL of saline, sprayed over the operated site, before release of the tourniquet; topical group), or intravenous saline (100 mL with anesthesia; control group). The volume of drained blood in 48 h, the amount of transfused blood, and the serum levels of hemoglobin and hematocrit before and after surgery were evaluated...
September 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/29050753/outcome-of-spray-cryotherapy-plus-functional-endoscopic-sinus-surgery-on-management-of-healing-in-nasal-polyposis
#4
Ahmad Rezaeian
BACKGROUND: Nasal Polyposis is a benign tumor in nasal or paranasal mucosa, which confronts difficulties in management of healing after treatments with surgery. The aim of this study was to evaluate the effects of Spray Cryotherapy (SCT) on management of healing in patients with nasal polyposis who undergone functional endoscopic sinus surgery. METHODS: In this prospective, clinical trial study, we investigated on 40 patients with nasal polyposis that had indication for functional endoscopic sinus surgery...
October 10, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/29040053/periostin-as-a-biomarker-for-nasal-polyps-in-chronic-rhinosinusitis
#5
Alice Z Maxfield, Lukas D Landegger, Christopher D Brook, Ashton E Lehmann, Adam P Campbell, Regan W Bergmark, Konstantina M Stankovic, Ralph Metson
Objective Periostin is an extracellular matrix protein that is elevated in the sinonasal tissues of patients with chronic rhinosinusitis (CRS). The purpose of this study was to determine whether serum periostin could serve as a molecular biomarker of nasal polyp burden in sinonasal disease. Study Design Prospective cohort study. Setting Academic medical center. Subjects and Methods Serum periostin levels were measured by ELISA on blood samples collected from patients undergoing sinus surgery for CRS (n = 71), further stratified by phenotype as defined by nasal polyps and asthma...
October 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29034344/hemocoagulase-might-not-control-but-worsen-gastrointestinal-bleeding-in-an-elderly-patient-with-type-ii-respiratory-failure
#6
Xingshun Qi, Jigang Wang, Xiaonan Yu, Valerio De Stefano, Hongyu Li, Chunyan Wu, Qingwei Zeng, Yongguo Zhang, Linan Ren, Hao Lin, Jiao Deng, Xiaozhong Guo
Hemocoagulase has been successfully used for the management of bleeding in patients undergoing surgery. Local spray of hemocoagulase during endoscopic therapy may be effective for the management of gastrointestinal bleeding. In China, intravenous infusion of hemocoagulase is given by some physicians for the treatment of gastrointestinal bleeding. However, the potential adverse events secondary to hemocoagulase, such as hypofibrinogenemia, are poorly recognized. In this paper, we reported an elderly patient with type II respiratory failure in whom hemocoagulase might induce hypofibrinogenemia and further worsen gastrointestinal bleeding...
2017: Translational Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29032297/postoperative-complications-following-primary-penile-inversion-vaginoplasty-among-330-male-to-female-transgender-patients
#7
Thomas W Gaither, Mohannad A Awad, E Charles Osterberg, Gregory P Murphy, Angelita Romero, Marci L Bowers, Benjamin N Breyer
PURPOSE: Studies of surgical complications from penile inversion vaginoplasty are limited due to small sample sizes. We describe postoperative complications after penile inversion vaginoplasty and evaluate age, BMI, and years on hormone replacement therapy (HRT) as risk factors for complications. MATERIALS AND METHODS: We conducted a retrospective review of male-to-female (MTF) patients presenting for primary penile inversion vaginoplasty to a high-volume surgeon (MLB) from 2011-2015...
October 11, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29030291/evaluation-of-a-spray-type-novel-dextrin-hydrogel-adhesion-barrier-under-laparoscopic-conditions-in-a-porcine-uterine-horn-adhesion-model
#8
Miho Kai, Kazuha Maeda, Masako Tasaki, Shinichirou Kira, Shintarou Nakamura, Naotaka Chino, Hitomi Hagiwara, Hitoshi Nishida, Tetsuro Kawanishi
STUDY OBJECTIVE: To establish a porcine uterine horn adhesion model that mimicked laparoscopic procedures and use it to investigate the effect of a spray-type, novel dextrin hydrogel adhesion barrier (AdSpray) on postsurgical adhesions. DESIGN: Single: Single-blind randomized controlled trial (Canadian Task Force Classification I). SETTING: Certified animal research facility. SUBJECTS: 16 female pigs. INTERVENTIONS: All animals underwent laparoscopically-assisted adhesion-inducing surgery...
October 10, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28982617/ointment-fistulography-introducing-a-novel-technique-for-single-or-multiple-urethrocutaneous-fistula-diagnosis-after-hypospadias-surgery
#9
Sarah Mozafarpour, Abdol-Mohammad Kajbafzadeh, Reza Abbasioun, Ali Akbar Habibi, Behnam Nabavizadeh
INTRODUCTION AND OBJECTIVE: Hypospadias is a common congenital malformation of the male genital tract. The most frequent complication after hypospadias repair is urethrocutaneous fistula.(1) Its incidence has been reported up to 35% worldwide.(2) The diagnosis of these fistulas is sometimes challenging particularly with tiny and multiple fistulas. Usually, parents complain of urinary spraying, sprinkling, or passing a single stream of urine from the undersurface of the penis after the surgery...
August 2017: Urology
https://www.readbyqxmd.com/read/28975430/clinical-assessment-of-diode-laser-assisted-endoscopic-intrasphenoidal-vidian-neurectomy-in-the-treatment-of-refractory-rhinitis
#10
Wen-Sen Lai, Sheng-Yao Cheng, Yuan-Yung Lin, Pei-Lin Yang, Hung-Che Lin, Li-Hsiang Cheng, Jinn-Moon Yang, Jih-Chin Lee
For chronic rhinitis that is refractory to medical therapy, surgical intervention such as endoscopic vidian neurectomy (VN) can be used to control the intractable symptoms. Lasers can contribute to minimizing the invasiveness of ENT surgery. The aim of this retrospective study is to compare in patients who underwent diode laser-assisted versus traditional VN in terms of operative time, surgical field, quality of life, and postoperative complications. All patients had refractory rhinitis with a poor treatment response to a 6-month trial of corticosteroid nasal sprays and underwent endoscopic VN between November 2006 and September 2015...
December 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28956319/a-comparison-of-tissue-spray-and-lipid-extract-direct-injection-electrospray-ionization-mass-spectrometry-for-the-differentiation-of-eutopic-and-ectopic-endometrial-tissues
#11
Vitaliy Chagovets, Zhihao Wang, Alexey Kononikhin, Natalia Starodubtseva, Anna Borisova, Dinara Salimova, Igor Popov, Andrey Kozachenko, Konstantin Chingin, Huanwen Chen, Vladimir Frankevich, Leila Adamyan, Gennady Sukhikh
Recent research revealed that tissue spray mass spectrometry enables rapid molecular profiling of biological tissues, which is of great importance for the search of disease biomarkers as well as for online surgery control. However, the payback for the high speed of analysis in tissue spray analysis is the generally lower chemical sensitivity compared with the traditional approach based on the offline chemical extraction and electrospray ionization mass spectrometry detection. In this study, high resolution mass spectrometry analysis of endometrium tissues of different localizations obtained using direct tissue spray mass spectrometry in positive ion mode is compared with the results of electrospray ionization analysis of lipid extracts...
September 27, 2017: Journal of the American Society for Mass Spectrometry
https://www.readbyqxmd.com/read/28931197/study-of-factors-responsible-for-recidivism-in-allergic-fungal-rhinosinusitis
#12
Bipin Kishore Prasad
Patients with allergic fungal rhinosinusitis (AFRS) are typically atopic and immunocompetent. Despite combined modality treatment based on surgery and immunomodulation, the potential for recidivism is well recognized. A study was conducted in a military hospital in India to identify the factors responsible for recidivism in AFRS and to suggest measures to overcome it. Sixty patients with AFRS (42 new cases and 18 cases that required revision surgery) were managed between January 2009 and July 2013. Patients underwent endoscopic, radiologic, and laboratory evaluation for AFRS followed by functional endoscopic sinus surgery...
September 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28927471/a-vascular-endothelial-growth-factor-a-genetic-variant-is-associated-with-improved-ventricular-function-and-transplant-free-survival-after-surgery-for-non-syndromic-chd
#13
Constantine D Mavroudis, Daniel Seung Kim, Nancy Burnham, Alexandra H Morss, Jerry H Kim, Amber A Burt, David R Crosslin, Donna M McDonald-McGinn, Elaine H Zackai, Meryl S Cohen, Susan C Nicolson, Thomas L Spray, Ian B Stanaway, Deborah A Nickerson, Mark W Russell, Hakon Hakonarson, Gail P Jarvik, J William Gaynor
BACKGROUND: We have previously shown that the minor alleles of vascular endothelial growth factor A (VEGFA) single-nucleotide polymorphism rs833069 and superoxide dismutase 2 (SOD2) single-nucleotide polymorphism rs2758331 are both associated with improved transplant-free survival after surgery for CHD in infants, but the underlying mechanisms are unknown. We hypothesised that one or both of these minor alleles are associated with better systemic ventricular function, resulting in improved survival...
September 20, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/28914872/-the-efficacy-of-desmopressin-in-the-treatment-of-central-diabetes-insipidus-after-resection-of-chiasmo-sellar-region-tumors
#14
L I Astaf'eva
Central diabetes insipidus (CDI) is a neuroendocrine disease, the pathogenesis of which is associated with abnormal secretion of the antidiuretic hormone. One of the specific causes of CDI is neurosurgical resection of chiasmatic-sellar region tumors. AIM: to study the efficacy and safety of desmopressin in CDI patients after resection of chiasmatic-sellar region (CSR) tumors. MATERIAL AND METHODS: Examination and treatment of patients were performed at a hospital for 7-14 days after surgery and then were continued after discharge...
2017: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
https://www.readbyqxmd.com/read/28881903/safety-and-efficacy-of-endoscopic-spray-cryotherapy-for-esophageal-cancer
#15
F C Tsai, S Ghorbani, B D Greenwald, S Jang, J A Dumot, M J McKinley, N J Shaheen, F Habr, H C Wolfsen, J A Abrams, C J Lightdale, N S Nishioka, M H Johnston, A Zfass, W J Coyle
Although surgery is traditionally the standard of care for esophageal cancer, esophagectomy carries significant morbidity. Alternative endoscopic therapies are needed for patients who are not candidates for conventional treatment. The objective of this study is to assess the safety, efficacy, and tolerability of spray cryotherapy of esophageal adenocarcinoma. This study includes patients with esophageal adenocarcinoma who had failed or were not candidates for conventional therapy enrolled retrospectively and prospectively in an open-label registry and patients in a retrospective cohort from 11 academic and community practices...
November 1, 2017: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/28859993/on-ciprofloxacin-concentration-in-chronic-rhinosinusitis
#16
José Gameiro Dos Santos, Rosário Figueirinhas, José P Liberal, João C Almeida, Joana Sousa, Amílcar Falcão, Corália Vicente, João Paço, Cecília A Sousa
OBJECTIVE: Considering that all the evidence indicates that chronic rhinosinusitis without nasal polyps (CRSsNP) and chronic rhinosinusitis with nasal polyps (CRSwNP) are distinct entities, the aim of this study was to compare the concentrations obtained in plasma and in sinonasal mucosa with oral and nasal topical ciprofloxacin, in patients with and without nasal polyps, without evaluating the effectiveness of the use of an antibiotic. METHODS: Prospective clinical study with single-blind randomization...
August 28, 2017: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/28859245/comparison-of-the-effect-of-aerosolized-fibrin-sealant-and-biodegradable-synthetic-polyurethane-foam-on-hemostasis-and-wound-healing-after-endoscopic-sinus-surgery-a-prospective-randomized-study
#17
Moon Sik Jung, Chang Hwan Choi, Myeong Sang Yu
BACKGROUND: Use of absorbable packing materials after functional endoscopic sinus surgery (FESS) is associated with increased patient comfort and a lack of need for packing removal. Different materials may induce different patterns of mucosal healing and hemostasis. This study investigated the effect of fibrin sealant (FS; Tisseel) or biodegradable synthetic polyurethane foam (Nasopore(®) ) packing on hemostasis and wound healing after FESS. METHODS: This prospective randomized controlled trial included 35 consecutive patients who underwent bilateral FESS for chronic rhinosinusitis...
August 31, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/28826991/parents-preferences-regarding-public-reporting-of-outcomes-in-congenital-heart-surgery
#18
Mallory L Irons, J William Gaynor, Thomas L Spray, Chris Feudtner
BACKGROUND: Calls for public reporting of outcomes in congenital heart surgery have led to several different reporting schemes, including a star rating system and benchmark procedure-specific mortality data tables. Important unanswered questions remain about the optimal format and content of public reporting of congenital heart surgery outcomes. METHODS: In conjunction with three parent advocacy groups, we developed a questionnaire to gauge parents' attitudes regarding the format and content of an "optimal" public reporting scheme...
August 19, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28803519/a-case-report-of-benzocaine-induced-methemoglobinemia
#19
Chaundra R Sewell, Michael P Rivey
Methemoglobinemia is a serious medical condition characterized by the disrupted binding of oxygen to iron on hemoglobin, with a consequent impaired oxygen delivery to body tissues. Various drugs including the local anesthetics such as benzocaine can cause acquired methemoglobinemia. The reported case describes methemoglobinemia that occurred in association with the use of topical benzocaine spray and lozenges in a previously healthy 51-year-old female who had undergone colon surgery to remove a bleeding polyp...
January 1, 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28766436/how-to-perform-nasal-douching
#20
Janette Bartle, Alexander Millington
Rationale and key points This article provides information on nasal douching, which nurses can use to advise patients on how to perform this procedure. It explains how to prepare and use a home-made solution for nasal douching, and discusses the various products available that can assist patients in undertaking this procedure. » Nasal douching, also known as nasal washout, irrigation or lavage, is recommended to clear mucus and allergens from the nose for people with rhinitis or rhinosinusitis. It is also recommended following nasal surgery to cleanse and aid healing inside the nose...
August 2, 2017: Nursing Standard
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