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Behavioral medicine

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https://www.readbyqxmd.com/read/28351019/online-microdialysis-ultra-performance-liquid-chromatography-mass-spectrometry-method-for-comparative-pharmacokinetic-investigation-on-iridoids-from-gardenia-jasminoides-ellis-in-rats-with-different-progressions-of-type-2-diabetic-complications
#1
Xueju Zhang, Lu Wang, Zhong Zheng, Zifeng Pi, Zhiqiang Liu, Fengrui Song
Iridoid glycosides consist the main bioactive constituents of Gardenia jasminoides Ellis (G. jasminoides), which is used alone or in combination with other medicine herbs for treatment of diabetes mellitus in China. This paper investigated for the first time comparative pharmacokinetics (PKs) of four unbound iridoids (including genipin, geniposide, gardenoside and geniposidic acid) in rat blood between healthy and type 2 diabetic groups with different disease progressions (9 or 13 weeks). Online microdialysis-ultra performance liquid chromatography-mass spectrometry (MD- UPLC-MS/MS) method was used after oral administration of iridoid extracts obtained from the fruits of G...
March 21, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28350836/perceived-psychosocial-stress-and-gestational-weight-gain-among-women-with-gestational-diabetes
#2
Ai Kubo, Assiamira Ferrara, Susan D Brown, Samantha F Ehrlich, Ai-Lin Tsai, Charles P Quesenberry, Yvonne Crites, Monique M Hedderson
Growing evidence links perceived stress-a potentially modifiable psychosocial risk factor-with health behaviors and obesity. Yet little is known about the relationship between stress during pregnancy and gestational weight gain, particularly among women with pregnancy complications. We conducted a cross-sectional analysis to examine associations between psychosocial stress during pregnancy and gestational weight gain among women with gestational diabetes. We used baseline data from the Gestational Diabetes's Effects on Moms (GEM) study: 1,353 women with gestational diabetes who delivered a term singleton within Kaiser Permanente Northern California were included...
2017: PloS One
https://www.readbyqxmd.com/read/28346622/future-of-family-medicine-faculty-development-in-sub-saharan-africa
#3
Paul R Larson, Patrick Chege, Bruce Dahlman, Christine Gibson, Ann Evensen, Maria C Colon-Gonzalez, Stephanie Onguka, Roberta Lamptey, William E Cayley, Bich-May Nguyen, Brian Johnson, Sawra Getnet, Memoona Hasnain
BACKGROUND AND OBJECTIVES: High-quality family medicine education is needed in sub-Saharan Africa to facilitate the future growth of primary care health systems. Current faculty educators recognize the value of dedicated teacher training and ongoing faculty development. However, they are constrained by inadequate faculty development program availability and institutional support. METHODS: A cross-sectional study design was used to conduct a qualitative needs assessment comprised of 37 in-depth, semi-structured interviews of individual faculty trainers from postgraduate family medicine training programs in eight sub-Saharan African countries...
March 2017: Family Medicine
https://www.readbyqxmd.com/read/28346603/residency-program-directors-interview-methods-and-satisfaction-with-resident-selection-across-multiple-specialties
#4
Tonya VanOrder, Wayne Robbins, Eric Zemper
CONTEXT: Competition for postdoctoral training positions is at an all-time high, and residency program directors continue to have little direction when it comes to structuring an effective interview process. OBJECTIVES: To examine whether a relationship existed between interview methods used and program director satisfaction with resident selection decisions and whether programs that used methods designed to assess candidate personal characteristics were more satisfied with their decisions...
April 1, 2017: Journal of the American Osteopathic Association
https://www.readbyqxmd.com/read/28346050/perception-of-canine-welfare-concerns-among-veterinary-students-practitioners-and-behavior-specialists-in-spain
#5
Isabel Luño, Jorge Palacio, Sylvia García-Belenguer, Ángela González-Martínez, Belén Rosado
Veterinarians are well placed to supervise and ensure canine welfare. However, the perception of animal welfare among veterinarians may vary depending on the level of training and professional practice, including the specialization in animal behavior and welfare. The aim of this study was to survey the perception of canine welfare among veterinarians, including students, practitioners, and behavior specialists. A scale-based questionnaire including 12 issues affecting canine welfare was adapted from Yeates and Main and distributed to first-year (n=50) and fifth-year veterinary students (n=50), as well as veterinary practitioners (n=260) and specialists in behavioral medicine (n=50)...
March 27, 2017: Journal of Veterinary Medical Education
https://www.readbyqxmd.com/read/28344484/the-prevalence-extent-of-complementary-and-alternative-medicine-cam-use-among-saudis
#6
REVIEW
Norah A Alrowais, Nada A Alyousefi
Introduction: There is worldwide interest in the use of CAM. Studying CAM in Saudi population is important as it will reflect the influence of psychosocial, cultural and religious factors on health beliefs and behaviors. The objective of this study was to present an updated review on the use of CAM practices in Saudi Arabia including commonly used types, common conditions for which it has been used and who uses CAM. Methods: This review used data from national surveys conducted in Saudi Arabia and published between 2000 and 2015...
March 2017: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://www.readbyqxmd.com/read/28344076/inhibition-of-human-cyp3a4-and-cyp3a5-enzymes-by-gomisin-c-and-gomisin-g-two-lignan-analogs-derived-from-schisandra-chinensis
#7
Jin Zhao, Tao Sun, Yun-Feng Cao, Zhong-Ze Fang, Hong-Zhi Sun, Zhi-Tu Zhu, Kun Yang, Yong-Zhe Liu, Frank J Gonzalez, Jing-Jing Wu, Jun Yin
Gomisin C (GC) and gomisin G (GG) are two lignan analogs isolated from the Traditional Chinese Medicine Schisandra chinensis which possesses multiple pharmacological activities. However, the potential herb-drug interactions (HDI) between these lignans and other drugs through inhibiting human cytochrome P450 3A4 (CYP3A4) and CYP3A5 remains unclear. In the present study, the inhibitory action of GC and GG on CYP3A4 and CYP3A5 were investigated. The results demonstrated that both GC and GG strongly inhibited CYP3A-mediated midazolam 1'-hydroxylation, nifedipine oxidation and testosterone 6β-hydroxylation...
March 23, 2017: Fitoterapia
https://www.readbyqxmd.com/read/28343561/locomotor-and-energetic-consequences-of-behavioral-thermoregulation-in-the-sanguivorous-leech-hirudo-verbana
#8
Amanda C Hitchcock, Erin M Connolly, Karin Darakananda, Janet W Jeong, Arbor J L Quist, Allison B Robbins, David J Ellerby
Medicinal leeches (Hirudo verbana) thermoregulate with respect to their sanguivorous feeding behavior. Immediate postprandial preferences are for warmer than their initial acclimation temperature (Ta, 21°C, Petersen et al. 2011), while unfed leeches have a lower preferred temperature (Tpref, 12.5°C). This may reduce energy expenditure and defer starvation if feeding opportunities are limited. Energetic benefits may have an associated cost if low temperatures reduce mobility and the ability to locate further hosts...
April 2017: Journal of Thermal Biology
https://www.readbyqxmd.com/read/28343283/the-types-of-trust-involved-in-american-muslim-healthcare-decisions-an-exploratory-qualitative-study
#9
Aasim I Padela, Liese Pruitt, Saleha Mallick
Trust in physicians and the healthcare system underlies some disparities noted among minority populations, yet a descriptive typology of different types of trust informing healthcare decisions among minority populations is limited. Using data from 13 focus groups with 102 American Muslims, we identified the types and influence of trust in healthcare decision-making. Participants conveyed four types of trust implicating their health-seeking behaviors-(I) trust in allopathic medicine, (II) trust in God, (III) trust in personal relationships, and (IV) trust in self...
March 25, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/28343109/a-visual-analysis-of-gender-bias-in-contemporary-anatomy-textbooks
#10
Rhiannon Parker, Theresa Larkin, Jon Cockburn
Empirical research has linked gender bias in medical education with negative attitudes and behaviors in healthcare providers. Yet it has been more than 20 years since research has considered the degree to which women and men are equally represented in anatomy textbooks. Furthermore, previous research has not explored beyond quantity of representation to also examine visual gender stereotypes and, in light of theoretical advancements in the area of intersectional research, the relationship between representations of gender and representations of ethnicity, body type, health, and age...
March 18, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28341247/toxicological-evaluation-of-oviductus-ranae-acute-sub-acute-and-genotoxicity-studies-in-mice-and-rats
#11
Yang Zhang, Kun Zhu, Hao Cui, Yang Liu, Ye-Fang Lu, Hong-Wei Pan, He-Peng Zhao, Ling Qi, Xiu-Dong Yang, Hong-Li Zhou
ETHNOPHARMACOLOGICAL RELEVANCE: Oviductus ranae (OR) is a traditional animal-based Chinese medicine, which has been listed in the Chinese Pharmacopoeia since 1985 edition. Although its medicinal application has been widely acknowleged, there is little available information on its potential toxicity. AIM OF THE STUDY: The aim of this study was to investigate the acute, sub-acute, and genetic toxicities of OR. MATERIALS AND METHODS: In acute toxicity evaluation, OR was administered orally to mice at doses of 2...
March 21, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28341220/national-academy-of-medicine-social-and-behavioral-measures-associations-with-self-reported-health
#12
Aric A Prather, Laura M Gottlieb, Nunzia B Giuse, Taneya Y Koonce, Sheila V Kusnoor, William W Stead, Nancy E Adler
INTRODUCTION: Social and behavioral factors play important roles in physical and mental health; however, they are not routinely assessed in the healthcare system. A brief panel of measures of social and behavioral determinants of health (SBDs) were recommended in a National Academy of Medicine report for use in electronic health records. Initial testing of the panel established feasibility of use and robustness of the measures. This study evaluates their convergent and divergent validity in relation to self-reported physical and mental health and social desirability bias...
March 21, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28339439/dezocine-antagonizes-morphine-analgesia-upon-simultaneous-administration-in-rodent-models-of-acute-nociception
#13
Na-Na Li, Ya-Qin Huang, Ling-Er Huang, Shao-Hui Guo, Maxwell R Shen, Chen-Ling Guo, Sheng-Mei Zhu, Yong-Xing Yao
BACKGROUND: Dezocine is a powerful analgesic that can be less addictive than morphine, yet how the two drugs interact in vivo is poorly understood. Here we administered dezocine alone or in combination with morphine to different acute nociception paradigms to explore the interactions of the 2 drugs upon co-administration. OBJECTIVE: To evaluate how dezocine interacts with morphine in different acute nociception paradigms. STUDY DESIGN: Laboratory animal study...
March 2017: Pain Physician
https://www.readbyqxmd.com/read/28338644/clinical-hypnosis-an-effective-mind-body-modality-for-adolescents-with-behavioral-and-physical-complaints
#14
REVIEW
Anju Sawni, Cora Collette Breuner
Mind-body medicine is a system of health practices that includes meditation/relaxation training, guided imagery, hypnosis, biofeedback, yoga, art/music therapy, prayer, t'ai chi, and psychological therapies such as cognitive behavioral therapy. Clinical hypnosis is an important mind-body tool that serves as an adjunct to conventional medical care for the adolescent patient. Clinical hypnosis specifically uses self-directed therapeutic suggestions to cultivate the imagination and facilitate the mind-body connection, leading to positive emotional and physical well-being...
March 24, 2017: Children
https://www.readbyqxmd.com/read/28338354/functional-oligopeptide-as-a-novel-strategy-for-drug-delivery
#15
Yujie Ji, Hongzhi Qiao, Jiayu He, Weidong Li, Rui Chen, Jingjing Wang, Li Wu, Rongfeng Hu, Jinao Duan, Zhipeng Chen
Oligopeptides, a type of short peptide, which consist of two to twenty amino acids, exhibit a variety of biological functions in drug delivery systems, such as specific targeting, cell penetration, self-assembled capacity and responsiveness to the environment. In this review, we aim to highlight the importance of functional oligopeptides for nanomedical applications and put forward the views on the future development direction of oligopeptide medicines. Oligopeptides have gained wide attentions due to their inherent properties, but the lack of understanding the mechanisms of in vivo transport behavior is the biggest problem and challenge at the present stage...
March 24, 2017: Journal of Drug Targeting
https://www.readbyqxmd.com/read/28338285/remote-control-of-cellular-functions-the-role-of-smart-nanomaterials-in-the-medicine-of-the-future
#16
REVIEW
Giada Graziana Genchi, Attilio Marino, Agostina Grillone, Ilaria Pezzini, Gianni Ciofani
The remote control of cellular functions through smart nanomaterials represents a biomanipulation approach with unprecedented potential applications in many fields of medicine, ranging from cancer therapy to tissue engineering. By actively responding to external stimuli, smart nanomaterials act as real nanotransducers able to mediate and/or convert different forms of energy into both physical and chemical cues, fostering specific cell behaviors. This report describes those classes of nanomaterials that have mostly paved the way to a "wireless" control of biological phenomena, focusing the discussion on some examples close to the clinical practice...
March 24, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28337648/diagnosis-and-treatment-of-alternating-hemiplegia-of-childhood
#17
REVIEW
Melanie Masoud, Lyndsey Prange, Jeffrey Wuchich, Arsen Hunanyan, Mohamad A Mikati
The diagnosis and treatment of patients with Alternating Hemiplegia of Childhood (AHC) and related disorders should be provided by a multidisciplinary team experienced with the spectrum of presentations of this disease, with its related disorders, with its complex and fluctuating manifestations, and with cutting edge advances occurring in the field. Involvement in research to advance the understanding of this disease and partnership with international collaborators and family organizations are also important...
February 2017: Current Treatment Options in Neurology
https://www.readbyqxmd.com/read/28336240/what-s-the-evidence-self-assessment-implications-for-life-long-learning-in-emergency-medicine
#18
Margaret Wolff, Sally A Santen, Laura R Hopson, Robin R Hemphill, Susan E Farrell
BACKGROUND: The 2012 Academic Emergency Medicine Consensus Conference, "Education Research in Emergency Medicine: Opportunities, Challenges, and Strategies for Success" noted that emergency medicine (EM) educators often rely on theory and tradition when molding their approaches to teaching and learning, and called on the EM education community to advance the teaching of our specialty through the performance and application of research in teaching and assessment methods, cognitive function, and the effects of education interventions...
March 20, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28333605/can-all-doctors-be-like-this-seven-stories-of-communication-transformation-told-by-physicians-rated-highest-by-patients
#19
Tom Janisse, Karen Tallman
INTRODUCTION: The top predictors of patient satisfaction with clinical visits are the quality of the physician-patient relationship and the communications contributing to their relationship. How do physicians improve their communication, and what effect does it have on them? This article presents the verbatim stories of seven high-performing physicians describing their transformative change in the areas of communication, connection, and well-being. METHODS: Data for this study are based on interviews from a previous study in which a 6-question set was posed, in semistructured 60-minute interviews, to 77 of the highest-performing Permanente Medical Group physicians in 4 Regions on the "Art of Medicine" patient survey...
2017: Permanente Journal
https://www.readbyqxmd.com/read/28333515/a-philosophy-for-behavioral-health-integration-in-primary-care
#20
Thomas R Egnew
In response to a call for a philosophy that transcends the professional boundaries that threaten behavioral health integration in primary care, this essay explores the thesis that such a philosophy exists in medicine's core purpose. Drawing on the work of Eric Cassell, a philosophy may be determined that melds the values, themes, and constructs of individual models for behavioral health integration in primary care toward a single, overriding purpose. Effecting such integration challenges current trends in medicine by refocusing medicine on its ethical core...
March 2017: Families, Systems & Health: the Journal of Collaborative Family Healthcare
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