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https://www.readbyqxmd.com/read/28527059/personality-disorders-in-cluster-headache-a-study-using-the-millon-clinical-multiaxial-inventory-iii
#1
Sylvie Hélène Marie Jeanne Piacentini, Lara Draghi, Alberto Proietti Cecchini, Massimo Leone
A great deal of studies suggests that cluster headache (CH) patients are usually comorbid to anxiety-mood spectrum disorders and psychopathological symptoms; however, the personality profiles reported in the literature strictly depend on type of assessment used. Psychiatric comorbidities have been extensively studied in migraine and they are recognized to represent a major risk factor associated with poorer outcome, playing a role in the headache chronification process at once as cause and consequence of it...
May 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28525360/role-of-sigma-1-receptor-in-high-fat-diet-induced-peripheral-neuropathy
#2
Tieying Song, Jianhui Zhao, Xiaojing Ma, Zaiwang Zhang, Bo Jiang, Yunliang Yang
The neurobiological mechanisms of obesity-induced peripheral neuropathy are poorly understood. We evaluated the role of Sigma-1 receptor (Sig-1R) and NMDA receptor (NMDARs) in the spinal cord in peripheral neuropathy using an animal model of high fat diet-induced diabetes. We examined the expression of Sig-1R and NMDAR subunits GluN2A and GluN2B along with postsynaptic density protein 95 (PSD-95) in the spinal cord after 24- week HFD treatment in both wild-type and Sig-1R-/- mice. Finally, we examined the effects of repeated intrathecal administrations of selective Sig-1R antagonists BD1047 in HFD-fed wild-type mice on peripheral neuropathy...
May 19, 2017: Biological Chemistry
https://www.readbyqxmd.com/read/28514836/oxidation-of-organic-contaminant-in-a-self-driven-electro-natural-maghemite-peroxydisulfate-system-efficiency-and-mechanism
#3
Suding Yan, Weihui Xiong, Shuya Xing, Yueqi Shao, Rui Guo, Hui Zhang
Electro-assisted iron-mediated persulfate (PS) activation process has been successfully employed to oxidize organic contaminant. However, a majority of iron-based catalysts used for PS activation was synthesized through complicated or demanding procedures and may have potential risks on environment during the preparation process. Herein, natural maghemite (NM) which is abundant on the earth was employed to activate peroxydisulfate (PDS) in an electrolytic cell. The voltage was provided by microbial fuel cell (MFC) instead of external power as reported in the previous studies, so as to establish a self-driven electro/natural maghemite/PDS system (MFC/NM/PDS) for the oxidation of acid orange 7 (AO7)...
May 12, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28511830/personality-disorders-and-the-difficult-dermatology-patient-maximizing-patient-satisfaction
#4
Mio Nakamura, John Koo
Personality disorders (PDs) are stable and enduring patterns of thought, feeling, and behavior that deviate from one's cultural norms and cause impairment in functionality. Patients with PDs are commonly encountered in the dermatologic setting and can be perceived by providers as "difficult." Given that PDs are chronic, rigid, and frustrating to deal with, it is important to be skillful in the approach to such patients, especially in the era of the value-based reimbursement system, in which patient satisfaction is crucial for reimbursement...
May 2017: Clinics in Dermatology
https://www.readbyqxmd.com/read/28504116/exercise-reverses-pain-related-weight-asymmetry-and-differentially-modulates-trabecular-bone-microarchitecture-in-a-rat-model-of-osteoarthritis
#5
Jim Cormier, Katherine Cone, Janell Lanpher, Abigail Kinens, Terry Henderson, Lucy Liaw, Edward J Bilsky, Tamara King, Clifford J Rosen, Glenn W Stevenson
There is great interest in developing and utilizing non-pharmacological/non-invasive forms of therapy for osteoarthritis (OA) pain including exercise and other physical fitness regimens. AIMS: The present experiments determined the effects of prior wheel running on OA-induced weight asymmetry and trabecular bone microarchitecture. MAIN METHODS: Wheel running included 7 or 21days of prior voluntary access to wheels followed by OA induction, followed by 21days post-OA access to wheels...
May 11, 2017: Life Sciences
https://www.readbyqxmd.com/read/28501782/combination-of-the-electro-fe-3-peroxydisulfate-pds-process-with-activated-sludge-culture-for-the-degradation-of-sulfamethazine
#6
Amina Ledjeri, Idris Yahiaoui, Hakima Kadji, Farida Aissani-Benissad, Abdeltif Amrane, Florence Fourcade
In this paper, the major factors affecting the degradation and the mineralization of sulfamethazine by Electro/Fe(3+)/peroxydisulfate (PDS) process (e.g. current density, PDS concentration, Fe(3+) ions concentration and initial sulfamethazine (SMT) concentration) were evaluated. The relevance of this process as a pretreatment prior to activated sludge culture was also examined. Regarding the impact on SMT degradation and mineralization, the obtained results showed that they were significantly enhanced by increasing the current density and the PDS concentrations in the ranges 1-40mAcm(-2) and from 1 to 10mM respectively; while they were negatively impacted by an increase of the initial SMT concentration and the Fe(3+) concentration, from 0...
May 1, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/28501657/effects-of-mentorship-on-graduating-vascular-surgery-trainees
#7
Matthew R Smeds, Cindy Huynh, Carol R Thrush, Mohammed M Moursi, Kwame S Amankwah
OBJECTIVE: Mentorship within surgery, particularly vascular surgery, has not been extensively evaluated. This study sought to examine mentorship experiences in graduating vascular trainees. METHODS: An anonymous electronic survey examining current mentor relationships, ideal characteristics, academic productivity and operative comfort level was emailed to all U.S. graduating 2015 (n=141) and 2016 (n=144) vascular trainees (VTs) during their last year of training...
May 10, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28501111/laparoscopic-dissection-and-division-of-distal-fistula-in-boys-with-rectourethral-fistula
#8
Chen Wang, Mei Diao, Long Li, Shuli Liu, Zheng Chen, Xu Li, Wei Cheng
BACKGROUND: Congenital rectourethral fistula (RUF) is the most common form of anorectal malformations found in boys. The aim of this study is to review our experience with dissection and division of distal fistula using laparoscopic surgery in the management of RUF, especially rectourethral bulbar fistula. METHODS: One hundred and two consecutive boys with congenital RUF who underwent conventional or single-incision laparoscopic surgery between July 2008 and June 2015 were enrolled in the study...
May 1, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28500977/endocytosis-and-intracellular-traffic-of-cholesterol-pdmaema-liposome-complexes-in-human-epithelial-like-cells
#9
F Szymanowski, A A Hugo, P Alves, P N Simões, A Gómez-Zavaglia, Pablo F Pérez
Liposomes are generally used as delivery systems, as they are capable of encapsulating a wide variety of molecules (i.e. plasmids, recombinant proteins, therapeutic drugs). However, liposomal drug delivery have to fulfill different requirements, such as the effective internalization by the target cells and avoidance of the degradative activity of the intracellular compartments. The use of polymer lipid complexes (PLCs), by including different polymers in the liposome formulation, could improve internalization and intracellular release of drugs...
May 1, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28496376/changing-trends-in-residents-as-teachers-across-graduate-medical-education
#10
Morhaf Al Achkar, Mathew Hanauer, Elizabeth H Morrison, M Kelly Davies, Robert C Oh
BACKGROUND: Teaching residents how to teach is a critical part of residents' training in graduate medical education (GME). The purpose of this study was to assess the change in resident-as-teacher (RaT) instruction in GME over the past 15 years in the US. METHODS: We used a quantitative and qualitative survey of all program directors (PDs) across specialties. We compared our findings with a previous work from 2000-2001 that studied the same matter. Finally, we qualitatively analyzed PDs' responses regarding the reasons for implementing and not implementing RaT instruction...
2017: Advances in Medical Education and Practice
https://www.readbyqxmd.com/read/28490472/-18-f-fdg-pet-ct-for-very-early-response-evaluation-predicts-ct-response-in-erlotinib-treated-nsclc-patients-a-comparison-of-assessment-methods
#11
Joan Fledelius, Anne Winther-Larsen, Azza Ahmed Khalil, Catharina Mølgaard Bylov, Karin Hjorthaug, Aksel Bertelsen, Jørgen Frøkiær, Peter Meldgaard
The purpose of this study was to determine which method for early response evaluation with (18)F-fluoro-D-glucose positron emission tomography combined with whole body computed tomography ((18)F-FDG-PET/CT) performed most optimal for prediction of response on a later CT-scan in erlotinib treated non-small cell lung cancer (NSCLC) patients. Methods:(18)F-FDG-PET/CT scans were performed prior to and after 7-10 days of erlotinib treatment in 50 NSCLC patients. The scans were evaluated using a qualitative approach and various semi-quantitative methods including percentage change in Standardized Uptake values, lean body mass corrected (SUL) SULpeak, SULmax and Total Lesion Glycolysis (TLG)...
May 10, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28490406/closure-of-nasal-septal-perforations-with-a-polydioxanone-plate-and-temporoparietal-fascia-in-a-closed-approach
#12
Lorenz Epprecht, Christoph Schlegel, David Holzmann, Michael Soyka, Thomas Kaufmann
BACKGROUND: Septal perforation closure is still often invasive and complex, with relatively low closure rates. OBJECTIVES: We aimed to provide the first results of a case series of 20 patients with nasal septal perforations who underwent septal perforation repair by both an open and a minimally invasive technique by using a graft that consisted of temporoparietal fascia and a polydioxanone (PDS) plate without mucosal flaps. Between 2014 and 2016, we tested, for the first time, the feasibility of the insertion of this graft via a hemitransfixion incision at our institution...
May 1, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/28489778/pancreatoduodenectomy-pd-and-postoperative-pancreatic-fistula-popf-a-systematic-review-and-analysis-of-the-popf-related-mortality-rate-in-60-739-patients-retrieved-from-the-english-literature-published-between-1990-and-2015
#13
Sergio Pedrazzoli
BACKGROUND: Pancreatoduodenectomy (PD) is one of the most technically demanding operations challenging surgeons, and a postoperative pancreatic fistula (POPF) can complicate an otherwise uneventful postoperative (PO) course. This review examined the methods and procedures used to prevent postoperative pancreatic fistula (POPF) after pancreatoduodenectomy (PD). METHODS: A comprehensive systematic search of the literature was performed using PubMed (Medline), Embase, Web of science, and the Cochrane databases for studies published between January 1, 1990 and December 31, 2015...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28484691/inflammatory-effects-of-the-plant-protection-product-stifenia-fen560-on-vertebrates
#14
Lény Teyssier, Julie Colussi, Stéphanie Delemasure, Johanna Chluba, David Wendehenne, Olivier Lamotte, Jean-Louis Connat
Plant defense stimulators (PDSs) rely on the activation of plant innate immunity in order to protect crops against various pests. These molecules are thought to be a safer alternative to classical plant protection products. Given that innate immune systems share common features in plants and vertebrates, PDS can potentially cross-react with innate immunity of non-target organisms. To test this hypothesis, we studied effects of the commercial PDS Stifenia (FEN560), which is composed of crushed fenugreek seeds...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28484060/prediction-of-primary-care-depression-outcomes-at-six-months-validation-of-doc-6-%C3%A2
#15
Kurt B Angstman, Gregory M Garrison, Cesar A Gonzalez, Daniel W Cozine, Elizabeth W Cozine, David J Katzelnick
BACKGROUND: The goal of this study was to develop and validate an assessment tool for adult primary care patients diagnosed with depression to determine predictive probability of clinical outcomes at 6 months. METHODS: We retrospectively reviewed 3096 adult patients enrolled in collaborative care management (CCM) for depression. Patients enrolled on or before December 31, 2013, served as the training set (n = 2525), whereas those enrolled after that date served as the preliminary validation set (n = 571)...
May 2017: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/28474986/ovarian-hormones-age-and-pubertal-development-and-their-association-with-days-of-headache-onset-in-girls-with-migraine-an-observational-cohort-study
#16
Vincent T Martin, Janelle R Allen, Timothy T Houle, Scott W Powers, Marielle A Kabbouche, Hope L O'Brien, Joanne Kacperski, Susan L LeCates, Shannon White, Polly Vaughan, Karen Mandell, Andrew D Hershey
Background Fifty-three percent of adolescent girls report headaches at the onset of menses, suggesting fluctuations of ovarian hormones trigger migraine during puberty. Aims To determine if urinary metabolites of estrogen and progesterone are associated with days of headache onset (HO) or severity in girls with migraine. Methods This was a pilot study and included 34 girls with migraine balanced across three age strata (pre-pubertal (8-11), pubertal (12-15), and post-pubertal (16-17) years of age). They collected daily urine samples and recorded the occurrence and severity of headache in a daily diary...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28474726/stable-ultra-fast-broad-bandwidth-photodetectors-based-on-%C3%AE-cspbi3-perovskite-and-nayf4-yb-er-quantum-dots
#17
Xisheng Zhang, Qian Wang, Zhiwen Jin, Jingru Zhang, Shengzhong Frank Liu
Photodetectors (PDs), especially those that respond in the infrared region, are highly desirable and have a wide range of applications ranging from cell phones, cameras, and home electronics to airplanes and satellites. Herein, we designed and fabricated PDs based on air-stable α-CsPbI3 QDs and an up-conversion material (NaYF4:Yb,Er QDs) using a facial low temperature spin-coating method. When the α-CsPbI3 QDs are surface-modified using NaYF4:Yb,Er QDs, their optical response is extended to the NIR region to allow broadband application from the UV to visible to NIR region (260 nm-1100 nm)...
May 18, 2017: Nanoscale
https://www.readbyqxmd.com/read/28466572/profiling-the-location-and-extent-of-musicians-pain-using-digital-pain-drawings
#18
Cinzia Cruder, Deborah Falla, Francesca Mangili, Laura Azzimonti, Liliana S Araújo, Aaron Williamon, Marco Barbero
BACKGROUND AND AIMS: According to the existing literature, musicians are at risk to experience a range of musculoskeletal painful conditions. Recently, digital technology has been developed to investigate pain location and pain extent. The aim of this study was to describe pain location and pain extent in musicians using a digital method for pain drawing analysis. Additionally, the association between pain drawing (PD) variables and clinical features in musicians with pain were explored...
May 2, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/28465124/a-multiple-reader-scoring-system-for-nasal-potential-difference-parameters
#19
George M Solomon, Bo Liu, Isabelle Sermet-Gaudelus, Isabelle Fajac, Michael Wilschanski, Francois Vermeulen, Steven M Rowe
BACKGROUND: Nasal Potential Difference (NPD) is a biomarker of CFTR activity used to diagnose CF and monitor experimental therapies. Limited studies have been performed to assess agreement between expert readers of NPD interpretation using a scoring algorithm. METHODS: We developed a standardized scoring algorithm for "interpretability" and "confidence" for PD (potential difference) measures, and sought to determine the degree of agreement on NPD parameters between trained readers...
April 29, 2017: Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society
https://www.readbyqxmd.com/read/28459711/a-cross-sectional-analysis-of-minimum-usmle-step-1-and-2-criteria-used-by-orthopaedic-surgery-residency-programs-in-screening-residency-applications
#20
John B Schrock, Matthew J Kraeutler, Michael R Dayton, Eric C McCarty
INTRODUCTION: The purpose of this study was to analyze how program directors (PDs) of orthopaedic surgery residency programs use United States Medical Licensing Examination (USMLE) Step 1 and 2 scores in screening residency applicants. METHODS: A survey was sent to each allopathic orthopaedic surgery residency PD. PDs were asked if they currently use minimum Step 1 and/or 2 scores in screening residency applicants and if these criteria have changed in recent years...
June 2017: Journal of the American Academy of Orthopaedic Surgeons
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