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https://www.readbyqxmd.com/read/29154953/correlation-between-cefepime-utilization-and-pseudomonas-aeruginosa-resistance-rate-to-beta-lactams-and-carbapenems-in-patients-with-healthcare-associated-infections
#1
Zorana M Djordjevic, Marko M Folic, Slobodan M Jankovic
OBJECTIVES: There is direct link between overutilization or abuse of antibiotics and P.aeruginosa resistance rate, but other factors could influence the resistance rate, too. The study aim was to observe changes of P.aeruginosa resistance rate in patients with hospital acquired infections (HAIs) after a period of cefepime unavailability in an intensive care unit (ICU). METHODS: The study was designed as retrospective observational analysis of trends in utilization of antibiotics and density of resistance to antibiotics...
November 14, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/29153902/robotic-buccal-mucosal-graft-ureteroplasty-for-complex-ureteral-stricture
#2
Sohrab Arora, Logan Campbell, Mouafak Tourojman, Daniel Pucheril, Lamont R Jones, Craig Rogers
OBJECTIVE: To demonstrate robot-assisted ureterolysis and buccal mucosal graft (BMG) ureteroplasty for the management of a complex, long recurrent ureteral stricture developing after ureterolysis, and also to demonstrate the use of near-infrared fluorescence (NIRF) imaging and intraoperative ureteroscopy during this procedure. METHODS: A 58-year-old man with a history of cabergoline treatment and a cardiac catheterization through the left groin presented with left flank pain and hydronephrosis...
December 2017: Urology
https://www.readbyqxmd.com/read/29151991/experiences-from-the-merger-of-clinics-in-the-swedish-public-dental-service-the-employee-perspective
#3
Christina Hassel Gustafsson, Anna-Lena Östberg
Objectives: The purpose of this study was to investigate the experiences of employees regarding the merger of clinics within the Public Dental Service (PDS), Västra Götaland Region, Sweden. Methods: Employees (dentists, dental hygienists, dental nurses) affected by both administrative and geographical mergers of dental clinics answered a web-based survey about experiences and effects of the merger process (n = 99, 47%). The Swedish short-form version of "The Nordic Questionnaire for Psychological and Social Factors at Work" (QPSNordic), the QPSNordic-34+ was used...
2017: Open Dentistry Journal
https://www.readbyqxmd.com/read/29149179/postmenopausal-hormone-therapy-and-risk-of-stroke-a-pooled-analysis-of-data-from-population-based-cohort-studies
#4
Germán D Carrasquilla, Paolo Frumento, Anita Berglund, Christer Borgfeldt, Matteo Bottai, Chiara Chiavenna, Mats Eliasson, Gunnar Engström, Göran Hallmans, Jan-Håkan Jansson, Patrik K Magnusson, Peter M Nilsson, Nancy L Pedersen, Alicja Wolk, Karin Leander
BACKGROUND: Recent research indicates a favourable influence of postmenopausal hormone therapy (HT) if initiated early, but not late, on subclinical atherosclerosis. However, the clinical relevance of timing of HT initiation for hard end points such as stroke remains to be determined. Further, no previous research has considered the timing of initiation of HT in relation to haemorrhagic stroke risk. The importance of the route of administration, type, active ingredient, and duration of HT for stroke risk is also unclear...
November 2017: PLoS Medicine
https://www.readbyqxmd.com/read/29145835/global-health-education-in-united-states-anesthesiology-residency-programs-a-survey-of-resident-opportunities-and-program-director-attitudes
#5
Gunisha Kaur, Sheida Tabaie, Jasmit Brar, Virginia Tangel, Kane O Pryor
BACKGROUND: Interest in global health during postgraduate residency training is increasing across medical specialties, and multiple disciplines have categorized global health training opportunities in their arena. No such cataloging exists for anesthesiology residency programs. The aim of this study was to assess and characterize global health opportunities and the attitudes of program directors (PDs) in U.S. anesthesiology residency programs towards this training. METHODS: A cross-sectional 20-question survey on global health opportunities was distributed to 128 ACGME accredited anesthesiology residency program directors via email between October 2015 and January 2016...
November 16, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/29144189/clinical-and-personality-disorders-in-a-danish-treatment-seeking-sample-of-intimate-partner-violence-perpetrators
#6
Ask Elklit, Siobhan Murphy, Christine Jacobsen, Morgan Kezia Jensen
Intimate partner violence (IPV) is a global public health concern with profound psychological consequences. Perpetrators often have a history of childhood trauma and a range of co-occurring psychiatric problems, which may have implications for treatment. This study examines the prevalence of psychiatric and personality disorders (PD) among perpetrators and the association between a range of demographic, childhood trauma, and adult criminality variables for the most prominent disorders. Data were collected from IPV perpetrators ( n = 529) engaging in a treatment program, ' Dialogue Against Violence'...
November 1, 2017: International Journal of Offender Therapy and Comparative Criminology
https://www.readbyqxmd.com/read/29139014/the-ictal-interictal-continuum-to-treat-or-not-to-treat-and-how
#7
Clio Rubinos, Alexandra S Reynolds, Jan Claassen
Continuous electroencephalography (cEEG) monitoring is becoming increasingly used in neurologic and non-neurologic intensive care units (ICUs). Non-convulsive seizures (NCSz) and periodic discharges (PDs) are commonly seen in critically ill patients. Some of these PD patterns, also known as the ictal-interictal continuum (IIC), are associated with an increased risk of seizures and poor outcome. However, we do not fully understand the significance of these periodic patterns and the decision of how aggressively to treat remains controversial...
November 14, 2017: Neurocritical Care
https://www.readbyqxmd.com/read/29138008/g-quadruplex-structure-at-intron-2-of-tfe3-and-its-role-in-xp11-2-translocation-and-splicing
#8
Shiv Prakash Verma, Parimal Das
Transcription Factor E3 (TFE3) translocation is found in a group of different type of cancers and most of the translocations are located in the 5' region of TFE3 which may be considered as Breakpoint Region (BR). In our In silico study by QGRS mapper and non BdB web servers we found a Potential G-quadruplex forming Sequence (PQS) in the intron 2 of TFE3 gene. In vitro G-quadruplex formation was shown by native PAGE in presence of Pyridostatin(PDS), which with inter molecular secondary structure caused reduced mobility to migrate slower...
November 11, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29135799/peripapillary-pachychoroid-syndrome
#9
Nopasak Phasukkijwatana, K Bailey Freund, Rosa Dolz-Marco, Mayss Al-Sheikh, Pearse A Keane, Catherine A Egan, Sandeep Randhawa, Jay M Stewart, Qingyun Liu, Alex P Hunyor, Allan Kreiger, Aaron Nagiel, Robert Lalane, Mansour Rahimi, Won Ki Lee, Lee Merrill Jampol, David Sarraf
PURPOSE: To describe the features of peripapillary pachychoroid syndrome (PPS), a novel pachychoroid disease spectrum (PDS) entity. METHODS: Medical records of 31 eyes (16 patients) with choroidal thickening associated with intraretinal and/or subretinal fluid in the nasal macula extending from the disk were reviewed (patients with PPS). Choroidal thickness was compared with 2 age-matched cohorts: typical PDS (17 eyes with central serous chorioretinopathy or pachychoroid neovasculopathy) and 19 normal eyes...
November 10, 2017: Retina
https://www.readbyqxmd.com/read/29134494/expression-of-telomere-associated-proteins-is-interdependent-to-stabilize-native-telomere-structure-and-telomere-dysfunction-by-g-quadruplex-ligand-causes-terra-upregulation
#10
Ratan Sadhukhan, Priyanka Chowdhury, Sourav Ghosh, Utpal Ghosh
Telomere DNA can form specialized nucleoprotein structure with telomere-associated proteins to hide free DNA ends or G-quadruplex structures under certain conditions especially in presence of G-quadruplex ligand. Telomere DNA is transcribed to form non-coding telomere repeat-containing RNA (TERRA) whose biogenesis and function is poorly understood. Our aim was to find the role of telomere-associated proteins and telomere structures in TERRA transcription. We silenced four [two shelterin (TRF1, TRF2) and two non-shelterin (PARP-1, SLX4)] telomere-associated genes using siRNA and verified depletion in protein level...
November 13, 2017: Cell Biochemistry and Biophysics
https://www.readbyqxmd.com/read/29132415/acupuncture-for-postprandial-distress-syndrome-apds-study-protocol-for-a-randomized-controlled-trial
#11
Jing-Wen Yang, Li-Wen Zhang, Guang-Xia Shi, Yi Du, Jun Wang, Jing-Jie Zhao, Yan Cao, Jian-Feng Tu, Shuai Zhang, Cheng Tan, San-San Chen, Cun-Zhi Liu
BACKGROUND: Postprandial distress syndrome (PDS) is referred to as meal-related functional dyspepsia (FD) and causes a reduced quality of life (QoL) for patients. Several randomized controlled trials (RCTs) have suggested that acupuncture is an effective treatment for FD, but few studies were particularly for PDS. This pilot study was designed to determine the feasibility and efficacy of acupuncture in patients with PDS characterized by postprandial fullness and early satiation according to the Rome III criteria...
November 13, 2017: Trials
https://www.readbyqxmd.com/read/29127807/electrochemical-activation-of-persulfates-at-bdd-anode-radical-or-nonradical-oxidation
#12
Haoran Song, Linxia Yan, Jin Jiang, Jun Ma, Zhongxiang Zhang, Jiaming Zhang, Pingxin Liu, Tao Yang
The combination of persulfates (peroxydisulfate (PDS) and peroxymonosulfate (PMS)) and electrolysis using boron-doped diamond (BDD) anode is a promising green advanced oxidation process. In comparison with electrolysis alone, electrochemical activation of persulfates at BDD anode considerably enhanced the degradation of carbamazepine (CBZ). The experimental results indicate that the surface-adsorbed hydroxyl radical (HO) played the dominant role. The generally proposed nonradical oxidation mechanism ignored hydroxyl radical (HO) oxidation because low concentration of radical scavenger (<10 M methanol or 5 M tertbutanol) could not effectively scavenge the surface-adsorbed HO...
October 12, 2017: Water Research
https://www.readbyqxmd.com/read/29125544/towards-optical-partial-discharge-detection-with-micro-silicon-photomultipliers
#13
Ming Ren, Jierui Zhou, Bo Song, Chongxing Zhang, Ming Dong, Ricardo Albarracín
Optical detection is reliable in intrinsically characterizing partial discharges (PDs). Because of the great volume and high-level power supply of the optical devices that can satisfy the requirements in photosensitivity, optical PD detection can merely be used in laboratory studies. To promote the practical application of the optical approach in an actual power apparatus, a silicon photomultiplier (SiPM)-based PD sensor is introduced in this paper, and its basic properties, which include the sensitivity, pulse resolution, correlation with PD severity, and electromagnetic (EM) interference immunity, are experimentally evaluated...
November 10, 2017: Sensors
https://www.readbyqxmd.com/read/29122068/prescription-of-panoramic-radiographs-in-children-a-health-services-assessment-of-current-guidelines
#14
Juan F Yepes, Elizabeth Powers, Tim Downey, George J Eckert, Qing Tang, LaQuia Vinson, Gerardo Maupomé
PURPOSE: To (1) determine adherence to guidelines when prescribing panoramic radiographs (PR) for patients 18 y.o. and younger; and 2) compare PR prescriptions between general dentists (GPs) and pediatric dentists (PDs). METHODS: A retrospective analysis of insurance claims included codes for PRs and associated codes for two cities between 2008 and 2015. Chi-square tests ascertained the likelihood of a PR being associated within three days of routine exams. RESULTS: A total of 81,699 pediatric patients were seen by 2,077 GPs and 103 PDs...
July 15, 2017: Pediatric Dentistry
https://www.readbyqxmd.com/read/29120278/assessment-of-pathological-traits-in-dsm-5-personality-disorders-by-the-dapp-bq-how-do-these-traits-relate-to-the-six-personality-disorder-types-of-the-alternative-model
#15
Han Berghuis, Theo J M Ingenhoven, Paul T van der Heijden, Gina M P Rossi, Chris K W Schotte
The six personality disorder (PD) types in DSM-5 section III are intended to resemble their DSM-IV/DSM-5 section II PD counterparts, but are now described by the level of personality functioning (criterion A) and an assigned trait profile (criterion B). However, concerns have been raised about the validity of these PD types. The present study examined the continuity between the DSM-IV/DSM-5 section II PDs and the corresponding trait profiles of the six DSM-5 section III PDs in a sample of 350 Dutch psychiatric patients...
November 9, 2017: Journal of Personality Disorders
https://www.readbyqxmd.com/read/29120195/personality-disorder-traits-perceptions-of-likability-impairment-and-ability-to-change-as-correlates-and-moderators-of-desired-level
#16
Joshua D Miller, Chelsea E Sleep, Joanna Lamkin, Colin Vize, W Keith Campbell, Donald R Lynam
Historical conceptualizations have framed personality disorders (PDs) as unchanging and ego-syntonic. However, recent evidence suggests that individuals with PD traits may have some insight into their personality and consider those traits to be somewhat ego-dystonic. To replicate and extend previous findings, participants (N = 328) self-reported their PD trait levels, likability of those traits, impairment, capability for change, and desired trait levels. The results demonstrated that individuals with PD traits tolerate but still dislike those traits, believe that they cause them problems, and are interested in reducing them...
November 9, 2017: Personality Disorders
https://www.readbyqxmd.com/read/29118562/obstetricians-and-gynecologists-knowledge-education-and-practices-regarding-chronic-hepatitis-b-in-pregnancy
#17
Bolin Niu, Dina Halegoua-De Marzio, Jonathan M Fenkel, Steven K Herrine
Background: In pregnant women with high viral loads, third-trimester initiation of antiviral agents can reduce the risk of vertical transmission. We aimed to assess obstetricians' and gynecologists' (OB-GYN) knowledge and clinical practice when treating pregnant women with chronic hepatitis B virus (HBV). Methods: All program directors (PDs) from 250 US OB-GYN residency programs were invited to anonymously complete an 18-item questionnaire. Descriptive statistics were calculated and analyzed...
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/29110561/efficacy-of-zonisamide-on-interictal-electroencephalography-in-familial-spontaneous-epileptic-cats
#18
Masayasu Ukai, Yuji Hamamoto, Yoshihiko Yu, Aki Fujiwara-Igarashi, Michio Fujita, Daisuke Hasegawa
Objectives The effectiveness of zonisamide (ZNS) against spontaneous epilepsy in cats has not yet been described. The purpose of this study was to investigate the effect of ZNS on interictal paroxysmal discharges (PDs) using scalp electroencephalography (EEG) in familial spontaneous epileptic cats (FSECs). Methods Eight FSECs were evaluated (six males and two females). Scalp EEG measurements were performed once a week for 3 weeks before ZNS administration (Pre-ZNS). Thereafter, administration of ZNS was started and an adjustment period was instituted until the drug in plasma achieved the steady state...
November 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/29103781/comparison-of-standard-suture-vs-barbed-suture-for-closing-the-porcine-knee-joint-evaluation-of-biomechanical-integrity-and-permeability
#19
Song Yang, Tang Qi-Heng, Zhou Yi-Xin
BACKGROUND: This study aimed to compare the biomechanical strength and permeability of barbed vs traditional suture for closure of the porcine knee joint. METHODS: This study used Duroc pig knee joints. For each specimen, a 5-cm medial parapatellar arthrotomy was performed with the knee at 30° of flexion. We closed the arthrotomy wound using barbed suture (size 1/0 V-Loc 180) or traditional suture (size 1/0 PDS II). Specimens were divided into a PDS II (n = 9) and a V-Loc group (n = 9) for biomechanical testing, and a PDS II (n = 9) and a V-Loc group (n = 9) for permeability testing...
October 10, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29099093/functional-dyspepsia
#20
REVIEW
Paul Enck, Fernando Azpiroz, Guy Boeckxstaens, Sigrid Elsenbruch, Christine Feinle-Bisset, Gerald Holtmann, Jeffrey M Lackner, Jukka Ronkainen, Michael Schemann, Andreas Stengel, Jan Tack, Stephan Zipfel, Nicholas J Talley
Functional dyspepsia is one of the most prevalent functional gastrointestinal disorders. Functional dyspepsia comprises three subtypes with presumed different pathophysiology and aetiology: postprandial distress syndrome (PDS), epigastric pain syndrome (EPS) and a subtype with overlapping PDS and EPS features. Functional dyspepsia symptoms can be caused by disturbed gastric motility (for example, inadequate fundic accommodation or delayed gastric emptying), gastric sensation (for example, sensations associated with hypersensitivity to gas and bloating) or gastric and duodenal inflammation...
November 3, 2017: Nature Reviews. Disease Primers
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