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https://www.readbyqxmd.com/read/27916357/triclosan-sutures-for-surgical-site-infection-in-colorectal-cancer
#1
Kanefumi Yamashita, Shinsuke Takeno, Seiichiro Hoshino, Hironari Shiwaku, Naoya Aisu, Yoichiro Yoshida, Syu Tanimura, Yuichi Yamashita
BACKGROUND: Among all procedures, surgical site infections (SSIs) in colorectal surgery continue to have the highest rate, accounting for 5%-45%. To prevent the bacterial colonization of suture material, which disables local mechanisms of wound decontamination, triclosan-coated sutures were developed. We assessed the effectiveness of triclosan-coated sutures used for skin closure on the rate of SSIs in colorectal cancer surgery. METHODS: Until August 2012, we used conventional methods for skin closure in colorectal cancer surgery at the Department of Gastroenterological Surgery, Fukuoka University Faculty of Medicine...
November 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27916269/optimizing-the-treatment-of-ovarian-cancer-neoadjuvant-chemotherapy-and-interval-debulking-versus-primary-debulking-surgery-for-epithelial-ovarian-cancers-likely-to-have-suboptimal-resection
#2
Sarah E Gill, Michaela E McGree, Amy L Weaver, William A Cliby, Carrie L Langstraat
OBJECTIVE: To: a) identify prognostic factors in patients with epithelial ovarian cancer treated with neoadjuvant chemotherapy (NACT) and interval debulking surgery (IDS), and b) compare post-surgical survival between patients treated with NACT/IDS for presumed unresectable disease and stage IIIC/IV patients who underwent suboptimal primary debulking surgery (PDS). METHODS: This was a retrospective study of consecutive stage IIIC or IV patients undergoing IDS after NACT at Mayo Clinic from January 2007 to December 2013...
December 1, 2016: Gynecologic Oncology
https://www.readbyqxmd.com/read/27906412/multiple-cluster-axis-ii-comorbidity-and-functional-outcome-in-severe-patients-with-borderline-personality-disorder
#3
Nerea Palomares, Antonia McMaster, Marina Díaz-Marsá, Irene de la Vega, Ana Montes, José Luis Carrasco
BACKGROUND: Current literature suggests that personality disorder comorbidity negatively contributes to both the severity and prognosis of other disorders; however, little literature has been devoted to its influence on borderline personality disorder (BPD). The objective of the present work is to study comorbidity with other personality disorders in a severe clinical sample of patients with BPD, and its relationship with global functionality. METHODS: A sample of 65 patients with severe borderline personality disorder was included in the study...
November 2016: Actas Españolas de Psiquiatría
https://www.readbyqxmd.com/read/27896512/cytoreduction-peritonectomy-procedures-combined-with-hyperthermic-intraperitoneal-chemotherapy-hipec-in-advanced-ovarian-cancer-retrospective-italian-multicenter-observational-study-of-511-cases
#4
Angelo Di Giorgio, Pierandrea De Iaco, Michele De Simone, Alfredo Garofalo, Giovanni Scambia, Antonio Daniele Pinna, Giorgio Maria Verdecchia, Luca Ansaloni, Antonio Macrì, Paolo Cappellini, Valerio Ceriani, Giorgio Giorda, Daniele Biacchi, Marco Vaira, Mario Valle, Paolo Sammartino
PURPOSE: The aim of this study was to help with the process of selecting patients with advanced ovarian cancer to undergo cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) by analyzing outcome data at distinct clinical time points reflecting the natural history of the disease. METHODS: In a retrospective Italian multicenter study investigating patients with advanced ovarian cancer who underwent CRS plus HIPEC between 1998 and 2014, we analyzed data for consecutive patients at eight treatment time points: primary debulking surgery (PDS); interval debulking surgery after partial response, after no response, and after a pathologic complete response to neoadjuvant chemotherapy; first recurrence with a progression-free interval >12, <12 months, or >12 months in patients who underwent further chemotherapy before CRS and HIPEC; and patients who underwent two or more CRS procedures and chemotherapy lines before CRS and HIPEC...
November 28, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27896508/trends-in-mortality-after-primary-cytoreductive-surgery-for-ovarian-cancer-a-systematic-review-and-metaregression-of-randomized-clinical-trials-and-observational-studies
#5
REVIEW
Violante Di Donato, Evangelos Kontopantelis, Giovanni Aletti, Assunta Casorelli, Ilaria Piacenti, Giorgio Bogani, Francesca Lecce, Pierluigi Benedetti Panici
BACKGROUND: Primary cytoreductive surgery (PDS) followed by platinum-based chemotherapy is the cornerstone of treatment and the absence of residual tumor after PDS is universally considered the most important prognostic factor. The aim of the present analysis was to evaluate trend and predictors of 30-day mortality in patients undergoing primary cytoreduction for ovarian cancer. METHODS: Literature was searched for records reporting 30-day mortality after PDS. All cohorts were rated for quality...
November 28, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27891464/awareness-of-eco-friendly-dentistry-among-dental-faculty-and-students-of-king-khalid-university-saudi-arabia
#6
Mohammed A Al-Qarni, Nasim Vahid Shakeela, Mohammed Abdullah Alamri, Yahya A Alshaikh
INTRODUCTION: Eco-friendly or green dentistry can be a reality by effectively designing dental clinics and using more eco-friendly materials in the clinical practice. AIM: To determine the awareness of eco-friendly dentistry among dental faculty and students in preparation for future implementation. MATERIALS AND METHODS: Assessment of knowledge regarding eco-friendly dentistry was done using an 18 item self-administered questionnaire among 160 participants...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27884806/exploring-qualitative-perspectives-on-surgical-resident-training-well-being-and-patient-care
#7
Lindsey Kreutzer, Allison R Dahlke, Remi Love, Kristen A Ban, Anthony D Yang, Karl Y Bilimoria, Julie K Johnson
BACKGROUND: The Flexibility In duty hour Requirements for Surgical Trainees (FIRST) Trial found not difference in patient outcomes or resident wellbeing between more restrictive and flexible duty hour policies. Qualitative methods are appropriate for better understanding the experience and perceptions of those affected by duty hour regulations. We conducted a pilot qualitative study on how resident duty hour regulations are perceived by general surgery Program Directors (PDs), surgical residents and attending surgeons who participated in the FIRST Trial...
November 8, 2016: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/27878582/chilli-leaf-curl-virus-based-vector-for-phloem-specific-silencing-of-endogenous-genes-and-overexpression-of-foreign-genes
#8
Nirbhay Kumar Kushwaha, Supriya Chakraborty
Geminiviruses are the largest and most devastating group of plant viruses which contain ssDNA as a genetic material. Geminivirus-derived virus-induced gene silencing (VIGS) vectors have emerged as an efficient and simple tool to study functional genomics in various plants. However, previously developed VIGS vectors have certain limitations, owing to their inability to be used in tissue-specific functional study. In the present study, we developed a Chilli leaf curl virus (ChiLCV)-based VIGS vector for its tissue-specific utilization by replacing the coat protein gene (open reading frame (ORF) AV1) with the gene of interest for phytoene desaturase (PDS) of Nicotiana benthamiana...
November 23, 2016: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/27878381/posttraumatic-stress-and-quality-of-life-with-the-totally-subcutaneous-compared-to-conventional-cardioverter-defibrillator-systems
#9
Julia Köbe, Katharina Hucklenbroich, Nils Geisendörfer, Markus Bettin, Gerrit Frommeyer, Florian Reinke, Dirk Dechering, Markus Burgmer, Lars Eckardt
BACKGROUND: For prevention of sudden cardiac death, the transvenously implantable cardioverter-defibrillator therapy (tv-ICD) is well accepted. The subcutaneous system (S-ICD(®)) is promising in terms of reducing ICD complications. Nevertheless, the impact of the novel generator position on patients' quality of life (QoL) is yet unknown. OBJECTIVE: This study aimed at comparing QoL and posttraumatic stress with both systems. METHODS: 60 S-ICD(®) and 60 case-controlled tv single-chamber ICD patients were asked to respond to three standardized questionnaires...
November 22, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27873183/interdisciplinary-oncology-education-a-national-survey-of-trainees-and-program-directors-in-the-united-states
#10
Adil S Akthar, Christopher D Hellekson, Sabha Ganai, Olwen M Hahn, Ronald J Maggiore, Ezra E Cohen, Mitchell C Posner, Steven J Chmura, Andrew R Howard, Daniel W Golden
Oncologists must have a strong understanding of collaborating specialties in order to deliver optimal cancer care. The objective of this study was to quantify current interdisciplinary oncology education among oncology training programs across the USA, identify effective teaching modalities, and assess communication skills training. Web-based surveys were sent to oncology trainees and program directors (PDs) across the USA on April 1, 2013 and October 8, 2013, respectively. Question responses were Yes/No, five-point Likert scales (1 = not at all, 2 = somewhat, 3 = moderately, 4 = quite, 5 = extremely), or free response...
November 21, 2016: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/27870700/patterns-of-recurrence-and-clinical-outcome-of-patients-with-stage-iiic-to-stage-iv-epithelial-ovarian-cancer-in-complete-response-after-primary-debulking-surgery-plus-chemotherapy-or-neoadjuvant-chemotherapy-followed-by-interval-debulking-surgery-an-italian
#11
Angiolo Gadducci, Stefania Cosio, Valentina Zizioli, Sara Notaro, Roberta Tana, Andrea Panattoni, Enrico Sartori
OBJECTIVE: The objective of this retrospective study was to assess the clinical outcome of patients with advanced epithelial ovarian cancer in complete response after primary debulking surgery (PDS) or neoadjuvant chemotherapy followed by interval debulking surgery (IDS]). METHODS: The authors reviewed the hospital records of 384 patients who underwent PDS (n = 322) or IDS (n = 62) and who were in complete response after primary treatment. RESULTS: Optimal (residual disease [RD] < 1 cm) and complete (no gross RD) cytoreduction rates were higher after IDS than after PDS (71...
November 17, 2016: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/27857331/highly-sensitive-uva-and-violet-photodetector-based-on-single-layer-graphene-tio-sub-2-sub-heterojunction
#12
Feng-Xia Liang, Deng-Yue Zhang, Jiu-Zhen Wang, Wei-Yu Kong, Zhi-Xiang Zhang, Yi Wang, Lin-Bao Luo
A highly sensitive ultraviolet A (UVA) and violet photodetector based on p-type single-layer graphene (SLG)-TiO<sub>2</sub> heterostructure was fabricated by transferring chemical vapor deposition derived SLG on the surface of commercial single-crystal TiO<sub>2</sub> wafer. Optoelectronic analysis reveals the as-fabricated Schottky junction PD was highly sensitive to light illumination in UVA and violet range, with peak sensitivity at 410 nm and excellent stability and reproducibility, but virtually blind to illumination with wavelength less than 350 nm or more than 460 nm...
November 14, 2016: Optics Express
https://www.readbyqxmd.com/read/27856724/variability-in-antibiotic-use-across-ontario-acute-care-hospitals
#13
Charlie Tan, Marian Vermeulen, Xuesong Wang, Rosemary Zvonar, Gary Garber, Nick Daneman
BACKGROUND: Antibiotic stewardship is a required organizational practice for Canadian acute care hospitals, yet data are scarce regarding the quantity and composition of antibiotic use across facilities. We sought to examine the variability, and risk-adjusted variability, in antibiotic use across acute care hospitals in Ontario, Canada's most populous province. METHODS: Antibiotic purchasing data from IMS Health, previously demonstrated to correlate strongly with internal antibiotic dispensing data, were acquired for 129 Ontario hospitals from January to December 2014 and linked to patient day (PD) denominator data from administrative datasets...
November 17, 2016: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/27855125/synthesis-and-optoelectronic-properties-of-quaternary-gainassb-alloy-nanosheets
#14
Xinliang Chen, Honglai Li, Zhaoyang Qi, Tiefeng Yang, Yankun Yang, Xuelu Hu, Xuehong Zhang, Xiaoli Zhu, Xiujuan Zhuang, Wei Hu, Anlian Pan
Quasi-one-dimensional (1D) nanostructures have been extensively explored for electronic and optoelectronic devices on account of their unique morphologies and versatile physical properties. Here, we report the successful synthesis of GaInAsSb alloy nanosheets by a simple chemical vapor deposition method. The grown GaInAsSb alloy nanosheets are pure zinc-blende single crystals, which show nanosize-induced extraordinary optoelectronic properties as compared with bulk materials. μ-Raman spectra exhibit a multi-mode phonon vibration behavior with clear frequency shifts under varied laser power...
December 16, 2016: Nanotechnology
https://www.readbyqxmd.com/read/27849364/assessment-of-dsm-5-section-ii-personality-disorders-with-the-mmpi-2-rf-in-a-nonclinical-sample
#15
Martin Sellbom, Alexander Smith
The Minnesota Multiphasic Personality Inventory-2-Restructured Form (MMPI-2-RF; Ben-Porath & Tellegen, 2008 / 2011 ) is frequently used in clinical practice. However, there has been a dearth of literature on how well this instrument can assess symptoms associated with personality disorders (PDs). This investigation examined a range of hypothesized MMPI-2-RF scales in predicting PD symptoms. We evaluated these associations in a sample of 397 university students who had been administered the MMPI-2-RF and the Structured Clinical Interview for DSM-IV Axis II Disorders-Personality Questionnaire (First, Gibbon, Spitzer, Williams, & Benjamin, 1997 )...
November 16, 2016: Journal of Personality Assessment
https://www.readbyqxmd.com/read/27848199/anesthesiology-resident-wellness-program-at-the-university-of-saskatchewan-concept-and-development
#16
Anita Chakravarti, Mateen Raazi, Jennifer O'Brien, Breanna Balaton
PURPOSE: We describe the need for an anesthesiology resident wellness program (ARWP) and the challenges associated with its development and implementation. We also present the results of a preliminary program evaluation. METHODS: We conducted a needs assessment of Canadian anesthesiology residency programs for a formal ARWP. This endeavor involved both a cross-sectional survey and a focus group of Canadian anesthesiology residency training program directors (PDs)...
November 15, 2016: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/27846423/in-silico-target-prediction-for-elucidating-the-mode-of-action-of-herbicides-including-prospective-validation
#17
Rucha K Chiddarwar, Sebastian G Rohrer, Antje Wolf, Stefan Tresch, Sabrina Wollenhaupt, Andreas Bender
The rapid emergence of pesticide resistance has given rise to a demand for herbicides with new mode of action (MoA). In the agrochemical sector, with the availability of experimental high throughput screening (HTS) data, it is now possible to utilize in silico target prediction methods in the early discovery phase to suggest the MoA of a compound via data mining of bioactivity data. While having been established in the pharmaceutical context, in the agrochemical area this approach poses rather different challenges, as we have found in this work, partially due to different chemistry, but even more so due to different (usually smaller) amounts of data, and different ways of conducting HTS...
November 6, 2016: Journal of Molecular Graphics & Modelling
https://www.readbyqxmd.com/read/27837388/a-longitudinal-study-of-pre-pregnancy-and-pregnancy-risk-factors-associated-with-antenatal-and-postnatal-symptoms-of-depression-evidence-from-growing-up-in-new-zealand
#18
Lisa Underwood, Karen E Waldie, Stephanie D'Souza, Elizabeth R Peterson, Susan M B Morton
Objectives Antenatal and postnatal depression can lead to poor outcomes for women and their children. The aim of this study was to explore whether risk factors differ for depression symptoms that are present during pregnancy and/or after childbirth. Methods An ethnically and socioeconomically diverse sample of 5301 women completed interviews during the third trimester of pregnancy and 9 months after childbirth. Depression symptoms were measured using the Edinburgh Postnatal Depression Scale (EPDS). Depression symptoms (defined as EPDS >12) among participants and associations with pre-pregnancy and pregnancy maternal characteristics were explored using logistic regression...
November 11, 2016: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/27836207/primary-debulking-surgery-of-the-upper-abdomen-and-the-diaphragm-with-a-plasma-device-surgery-system-for-advanced-ovarian-cancer
#19
Gloria Cordeiro Vidal, Guillaume Babin, Denis Querleu, Frédéric Guyon
OBJECTIVE: Electrically neutral argon plasma (PlasmaJet™) technology is a surgical option that helps to get an aggressive cytoreduction in selected patients with ovarian cancer because it can be directly applied by the surgeon to treat the tissue surface [1,2]. Upper abdominal surgical procedures are an important part of the surgery in these patients [3], there is a 22% complications rate when they are performed [4]. We present a surgical approach to ovarian cancer debulking using PlasmaJet™...
November 8, 2016: Gynecologic Oncology
https://www.readbyqxmd.com/read/27834172/impact-of-new-traumatic-or-stressful-life-events-on-pre-existing-ptsd-in-traumatized-refugees-results-of-a-longitudinal-study
#20
Katrin Schock, Maria Böttche, Rita Rosner, Mechthild Wenk-Ansohn, Christine Knaevelsrud
BACKGROUND: A significant proportion of trauma survivors experience an additional critical life event in the aftermath. These renewed experiences of traumatic and stressful life events may lead to an increase in trauma-related mental health symptoms. METHOD: In a longitudinal study, the effects of renewed experiences of a trauma or stressful life event were examined. For this purpose, refugees seeking asylum in Germany were assessed for posttraumatic stress symptoms (PTS), Posttraumatic Stress Diagnostic Scale (PDS), anxiety, and depression (Hopkins Symptom Checklist [HSCL-25]) before treatment start as well as after 6 and 12 months during treatment (N=46)...
2016: European Journal of Psychotraumatology
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