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https://www.readbyqxmd.com/read/28227944/classification-of-squat-quality-with-inertial-measurement-units-in-the-single-leg-squat-mobility-test
#1
Rezvan Kianifar, Alex Lee, Sachin Raina, Dana Kulic, Rezvan Kianifar, Alex Lee, Sachin Raina, Dana Kulic, Alex Lee, Sachin Raina, Dana Kulic, Rezvan Kianifar
Many assessment and diagnosis protocols in rehabilitation, orthopedic surgery and sports medicine rely on mobility tests like the Single Leg Squat (SLS). In this study, a set of three Inertial Measurement Units (IMUs) were used to estimate the joint pose during SLS and to classify the SLS as poor, moderate or good. An Extended Kalman Filter pose estimation method was used to estimate kinematic joint variables, and time domain features were generated based on these variables. The most important features were then selected and used to train Support Vector Machine (SVM), Linear Multinomial Logistic Regression, and Decision Tree classifiers...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227789/addressing-drug-drug-and-drug-food-interactions-through-personalized-empowerment-services-for-healthcare
#2
Marios Spanakis, Emmanouil G Spanakis, Haridimos Kondylakis, Stelios Sfakianakis, Irini Genitsaridi, Vangelis Sakkalis, Manolis Tsiknakis, Kostas Marias, Marios Spanakis, Emmanouil G Spanakis, Haridimos Kondylakis, Stelios Sfakianakis, Irini Genitsaridi, Vangelis Sakkalis, Manolis Tsiknakis, Kostas Marias, Manolis Tsiknakis, Haridimos Kondylakis, Kostas Marias, Stelios Sfakianakis, Irini Genitsaridi, Emmanouil G Spanakis, Vangelis Sakkalis, Marios Spanakis
Personalized healthcare systems support the provision of timely and appropriate information regarding healthcare options and treatment alternatives. Especially for patients that receive multi-drug treatments a key issue is the minimization of the risk of adverse effects due to drug-drug interactions (DDIs). DDIs may be the result of doctor prescribed drugs but also due to self-medication of conventional drugs, alternative medicines, food habits, alcohol or smoking. It is therefore crucial for personalized health systems, apart from assisting physicians for optimal prescription practices, to also provide appropriate information for individual users for drug-drug interactions or similar information regarding risks for modulation of the ensuing treatment...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227449/comparison-of-methods-for-the-evaluation-of-nibp-from-pulse-transit-time
#3
L Peter, N Noury, M Cerny, I Nykl, L Peter, N Noury, M Cerny, I Nykl, L Peter, I Nykl, N Noury, M Cerny
Non-invasive blood pressure measurement (NIBP) is one of the most discussed topic in cardiovascular medicine. Currently continuous measurement of blood pressure is possible by invasive methods, which makes the measurement impractical for Doctors and uncomfortable for the patients. It is possible to use special devices to measure blood pressure noninvasively continuously but there are still some problems with long time monitoring and comfort for patient. Physiologically there is connection between electrical and mechanical heart functions, propagation of pulse wave and blood pressure value...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227367/statistical-identification-of-stimulus-activated-network-nodes-in-multi-neuron-voltage-sensitive-dye-optical-recordings
#4
Elham Fathiazar, Jorn Anemuller, Jutta Kretzberg, Elham Fathiazar, Jorn Anemuller, Jutta Kretzberg, Elham Fathiazar, Jutta Kretzberg, Jorn Anemuller
Voltage-Sensitive Dye (VSD) imaging is an optical imaging method that allows measuring the graded voltage changes of multiple neurons simultaneously. In neuroscience, this method is used to reveal networks of neurons involved in certain tasks. However, the recorded relative dye fluorescence changes are usually low and signals are superimposed by noise and artifacts. Therefore, establishing a reliable method to identify which cells are activated by specific stimulus conditions is the first step to identify functional networks...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227338/surface-electromyography-based-muscle-fatigue-analysis-for-stroke-patients-at-different-brunnstrom-stages
#5
Yinjun Tu, Zhe Zhang, Xudong Gu, Qiang Fang, Yinjun Tu, Zhe Zhang, Xudong Gu, Qiang Fang, Qiang Fang, Zhe Zhang, Yinjun Tu, Xudong Gu
Muscle fatigue analysis has been an important topic in sport and rehabilitation medicine due to its role in muscle performance evaluation and pathology investigation. This paper proposes a surface electromyography (sEMG) based muscle fatigue analysis approach which was specifically designed for stroke rehabilitation applications. 14 stroke patients from 5 different Brunnstrom recovery stage groups were involved in the experiment and features including median frequency and mean power frequency were extracted from the collected sEMG samples for investigation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227308/analyzing-the-influence-of-curl-speed-in-fatiguing-biceps-brachii-muscles-using-semg-signals-and-multifractal-detrended-moving-average-algorithm
#6
Kiran Marri, Ramakrishnan Swaminathan, Kiran Marri, Ramakrishnan Swaminathan, Kiuuwncran Marri, Ramakrishnan Swaminathan
In this work, an attempt has been made to analyze surface electromyography (sEMG) signals of fatiguing biceps brachii muscles at different curl speeds using multifractal detrended moving average (MFDMA) algorithm. For this purpose, signals are recorded from fifty eight healthy subjects while performing curl exercise at their comfortable speed until fatigue. The signals of first and last curls are considered as nonfatigue and fatigue conditions, respectively. Further, the number of curls performed by each subject and the endurance time is used for computing the normalized curl speed...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227254/a-data-science-approach-for-quantifying-spatio-temporal-effects-to-graft-failures-in-organ-transplantation
#7
Diego Pinheiro, Farag Hamad, Martin Cadeiras, Ronaldo Menezes, Nezamoddin Nezamoddini-Kachouie, Diego Pinheiro, Farag Hamad, Martin Cadeiras, Ronaldo Menezes, Nezamoddin Nezamoddini-Kachouie, Farag Hamad, Martin Cadeiras, Diego Pinheiro, Ronaldo Menezes, Nezamoddin Nezamoddini-Kachouie
The transplantation of solid organs is one of the most important accomplishments of modern medicine. Yet, organ shortage is a major public health issue; 8,000 people died while waiting for an organ in 2014. Meanwhile, the allocation system currently implemented can lead to organs being discarded and the medical community still investigates factors that affects early graft failure such as distance and ischemic time. In this paper, we investigate early graft failure under a spatio-temporal perspective using a data science unified approach for all six organs that is based on complementary cumulative analysis of both distance and ischemic time...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227234/computational-human-model-vhp-female-derived-from-datasets-of-the-national-library-of-medicine
#8
Gregory M Noetscher, Janakinadh Yanamadala, Harshal Tankaria, Sara Louie, Alexander Prokop, Ara Nazarian, Sergey N Makarov, Gregory M Noetscher, Janakinadh Yanamadala, Harshal Tankaria, Sara Louie, Alexander Prokop, Ara Nazarian, Sergey N Makarov, Ara Nazarian, Janakinadh Yanamadala, Gregory M Noetscher, Sergey N Makarov, Alexander Prokop, Harshal Tankaria, Sara Louie
Simulation of the electromagnetic response of the human body relies upon efficient computational models. The objective of this paper is to describe a new platform-independent and computationally-efficient full-body electromagnetic model, the Visible Human Project® (VHP)-Female v.3.0 and to outline its distinct features. We also report model performance results using two leading commercial electromagnetic antenna simulation packages: ANSYS HFSS and CST MICROWAVE STUDIO®.
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227231/the-visible-human-project-%C3%A2-from-body-to-bits
#9
Michael J Ackerman, Michael J Ackerman, Michael J Ackerman
In the middle 1990's the U.S. National Library sponsored the acquisition and development of the Visible Human Project(®) data base. This image database contains anatomical cross-sectional images which allow the reconstruction of three dimensional male and female anatomy to an accuracy of less than 1.0 mm. The male anatomy is contained in a 15 gigabyte database, the female in a 39 gigabyte database. This talk will describe why and how this project was accomplished and demonstrate some of the products which the Visible Human dataset has made possible...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227149/automated-and-reconfigurable-platform-for-niosome-generation-based-on-a-microfluidic-architecture
#10
Frederic Tessier, Myriam Laprise-Pelletier, Eric Boilard, Marc-Andre Fortin, Amine Miled, Frederic Tessier, Myriam Laprise-Pelletier, Eric Boilard, Marc-Andre Fortin, Amine Miled, Marc-Andre Fortin, Eric Boilard, Amine Miled, Frederic Tessier, Myriam Laprise-Pelletier
Drug delivery at the nano-scale is becoming an important topic in nano and regenerative medicine as it can offer a very localized therapy. Therefore, niosomes are one of the most important vehicles to release drug at the nanoscale. In this paper, we present a new automated microsystem for niosome generation on-demand. Used niosome were based on a mixture of cholesterol and dicetyl phosphate with chloroform. Three compact micropumps are connected to a microfluidic substrate in order to generate 100 nm noisome vesicles...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227138/assessment-of-autonomic-neurodevelopment-in-the-mouse-fetuses-by-using-fetal-electrocardiography
#11
Ahsan H Khandoker, Thuraia Al Khoori, Takuya Ito, Rika Sugibayashi, Yoshitaka Kimura, Ahsan H Khandoker, Thuraia Al Khoori, Takuya Ito, Rika Sugibayashi, Yoshitaka Kimura, Thuraia Al Khoori, Yoshitaka Kimura, Rika Sugibayashi, Takuya Ito, Ahsan H Khandoker
Fetal Electrocardiography (FECG) offers unique capabilities for assessment of beat-to-beat fetal heart rate (FHR) and fetal heart rate variability (FHRV), which are indirect markers of autonomic nervous system, its development. In this study the fetal ECG signals, FHR and FHRV are successfully recorded to assess the neurodevelopment in fetal mice in the second and third trimester from days 12.5 to 18.5 by using direct insertion of fetal ECG electrodes in the uterine. FHR increases from day 12.5 till 15.5 reaching a plateau and then shows a sudden increase on the day 18...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227016/towards-sophisticated-learning-from-ehrs-increasing-prediction-specificity-and-accuracy-using-clinically-meaningful-risk-criteria
#12
Ieva Vasiljeva, Ognjen Arandjelovic, Ieva Vasiljeva, Ognjen Arandjelovic, Ieva Vasiljeva, Ognjen Arandjelovic
Computer based analysis of Electronic Health Records (EHRs) has the potential to provide major novel insights of benefit both to specific individuals in the context of personalized medicine, as well as on the level of population-wide health care and policy. The present paper introduces a novel algorithm that uses machine learning for the discovery of longitudinal patterns in the diagnoses of diseases. Two key technical novelties are introduced: one in the form of a novel learning paradigm which enables greater learning specificity, and another in the form of a risk driven identification of confounding diagnoses...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226540/micro-tube-mass-production-device-for-microbial-culture
#13
K Fujimoto, M Ogawa, K Higashi, N Miki, K Fujimoto, M Ogawa, K Higashi, N Miki, K Higashi, K Fujimoto, M Ogawa, N Miki
This paper describes mass production system of micro-tubes for microbial culture in an open environment. Microbes are used in many fields, such as food, medicine, environmental and energy. We proposed a microbe culture system using hydrogel micro-tubes, which can protect the target microbes inside from competitive microbes outside of the tubes while allow oxygen and nutrition to diffuse through. The hydrogel micro-tubes can be produced by a microfluidic device, which can precisely control the flow and therefore, the tube geometry...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226489/3d-printed-microfluidic-mixer-for-point-of-care-diagnosis-of-anemia
#14
Kimberly Plevniak, Matthew Campbell, Mei He, Kimberly Plevniak, Matthew Campbell, Mei He, Matthew Campbell, Mei He, Kimberly Plevniak
3D printing has been an emerging fabrication tool in prototyping and manufacturing. We demonstrated a 3D microfluidic simulation guided computer design and 3D printer prototyping for quick turnaround development of microfluidic 3D mixers, which allows fast self-mixing of reagents with blood through capillary force. Combined with smartphone, the point-of-care diagnosis of anemia from finger-prick blood has been successfully implemented and showed consistent results with clinical measurements. Capable of 3D fabrication flexibility and smartphone compatibility, this work presents a novel diagnostic strategy for advancing personalized medicine and mobile healthcare...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226421/opening-plenary-speaker-human-genomics-precision-medicine-and-advancing-human-health
#15
Eric D Green
Starting with the launch of the Human Genome Project in 1990, the past quarter-century has brought spectacular achievements in genomics that dramatically empower the study of human biology and disease. The human genomics enterprise is now in the midst of an important transition, as the growing foundation of genomic knowledge is being used by researchers and clinicians to tackle increasingly complex problems in biomedicine. Of particular prominence is the use of revolutionary new DNA sequencing technologies for generating prodigious amounts of DNA sequence data to elucidate the complexities of genome structure, function, and evolution, as well as to unravel the genomic bases of rare and common diseases...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226397/innate-lymphoid-cells-in-asthma-cannabinoids-on-the-balance
#16
EDITORIAL
Kayluz Frias Boligan, Stephan von Gunten
The network of cells and soluble mediators implicated in the pathogenesis of asthma and allergic disorders is complex. Deciphering details of the crosstalk between its components is essential for the identification of novel drug targets and for advances in patient management and precision medicine (1, 2). There is increasing evidence that innate lymphoid cells (ILCs) contribute to allergic responses (3). This article is protected by copyright. All rights reserved.
February 22, 2017: Allergy
https://www.readbyqxmd.com/read/28226375/trends-in-nasal-subunit-reconstruction-by-facial-plastic-and-reconstructive-surgeons
#17
Yuna C Larrabee, David J Phillips, Anthony P Sclafani
To determine if facial plastic and reconstructive surgeons still adhere to the classic nasal subunit principle as described by Burget and Menick. Observational survey. A Weill Cornell Medicine institutional review board approved electronic survey that was sent via e-mail to active members of the American Academy of Facial Plastic and Reconstructive Surgery (AAFPRS). The survey consisted of 32 multiple-choice questions pertaining to the operative management of small (22-30%), medium (50-58%), and large (75-81%) defects of each subunit of the nose, as well as demographic, provider, and practice characteristics...
February 2017: Facial Plastic Surgery: FPS
https://www.readbyqxmd.com/read/28226339/current-concepts-of-phenylpiperidine-derivatives-use-in-the-treatment-of-acute-and-chronic-pain
#18
Nidal Elbaridi, Alan D Kaye, Stephanie Choi, Richard D Urman
Phenylpiperidines are a chemical class of drugs with a phenyl moiety directly attached to piperidine. These agents have an important role in many aspects of medicine including anesthesia and pain medicine. After the development of meperidine, fentanyl, which is a second generation synthetic phenylpiperidine series opioid, was synthesized and introduced into clinical anesthesia practice as fentanyl citrate in 1968. Fentanyl-mediated or modulated responses involve action at the mu-opioid receptor as an agonist at the dorsal horn inhibiting ascending pain pathways in the rostral ventral medulla, increasing pain threshold, and producing both analgesic and sedative effects...
February 2017: Pain Physician
https://www.readbyqxmd.com/read/28226302/towards-a-theoretical-model-on-medicines-as-a-health-need
#19
Claudia Marcela Vargas-Peláez, Luciano Soares, Marina Raijche Mattozo Rover, Carine Raquel Blatt, Aukje Mantel-Teeuwisse, Francisco Augusto Rossi Buenaventura, Luis Guillermo Restrepo, María Cristina Latorre, José Julián López, María Teresa Bürgin, Consuelo Silva, Silvana Nair Leite, Farias Mareni Rocha
Medicines are considered one of the main tools of western medicine to resolve health problems. Currently, medicines represent an important share of the countries' healthcare budget. In the Latin America region, access to essential medicines is still a challenge, although countries have established some measures in the last years in order to guarantee equitable access to medicines. A theoretical model is proposed for analysing the social, political, and economic factors that modulate the role of medicines as a health need and their influence on the accessibility and access to medicines...
February 15, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28226204/brief-report-current-status-of-pathologic-examinations-in-korea-2011-2015-based-on-the-health-insurance-review-and-assessment-service-dataset
#20
Sun-Ju Byeon
Background: Pathologic examinations play an important role in medical services. Until recently, the overall status of pathologic examinations in Korea has not been identified. I conducted a nationwide survey of pathologic examination status using the insurance reimbursements (IRs) dataset from the Health Insurance Review and Assessment Service (HIRA). The aims of this study were to estimate current pathologic examination status in Korea and to provide information for future resource arrangement in the pathology era...
February 22, 2017: Journal of Pathology and Translational Medicine
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