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thyroid nodule guidelines

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https://www.readbyqxmd.com/read/29323546/validation-of-the-2015-american-thyroid-association-management-guidelines-for-thyroid-nodules-with-benign-cytologic-findings-in-the-era-of-the-bethesda-system
#1
Yeun-Yoon Kim, Kyunghwa Han, Eun-Kyung Kim, Hee Jung Moon, Jung Hyun Yoon, Vivian Y Park, Jin Young Kwak
OBJECTIVE: The purpose of this study is to investigate follow-up strategies for cytologically benign thyroid nodules according to size and ultrasound (US) pattern according to the 2015 American Thyroid Association (ATA) guidelines in the era of the Bethesda system. MATERIALS AND METHODS: This retrospective study included 1208 patients with 1230 nodules that were cytologically benign at initial fine-needle aspiration performed from June 2012 to December 2014. False-negative rates (FNRs) were calculated by considering nodule size and US pattern according to the 2015 ATA guidelines and were compared between nodules with the high-suspicion US pattern and nodules with the high- or intermediate-suspicion US patterns according to size...
January 11, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29288581/comparison-of-different-gauge-needles-for-fine-needle-aspiration-biopsy-of-thyroid-nodules
#2
Lili Zhang, Yujiang Liu, Xiaoqu Tan, Xi Liu, Hong Zhang, Linxue Qian
OBJECTIVES: To compare the adequacy of 23-, 25-, and 27-gauge needles in the fine-needle aspiration biopsy of thyroid nodules to develop guidelines for the collection of better specimens for cytologic diagnosis. METHODS: This randomized prospective study included 156 consecutively enrolled patients with 156 nodules. Each nodule was aspirated with a needle of each size. The obtained specimens were analyzed independently by 2 cytopathologists, and adequacy rates were calculated...
December 30, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29286180/computer-aided-system-for-diagnosing-thyroid-nodules-on-ultrasound-a-comparison-with-radiologist-based-clinical-assessments
#3
Luying Gao, Ruyu Liu, Yuxin Jiang, Wenfeng Song, Ying Wang, Jia Liu, Juanjuan Wang, Dongqian Wu, Shuai Li, Aimin Hao, Bo Zhang
BACKGROUND: The purpose of this study was to compare the diagnostic efficiency of a thyroid ultrasound computer-aided diagnosis (CAD) system with that of 1 radiologist. METHODS: This study retrospectively reviewed 342 surgically resected thyroid nodules from July 2013 to December 2013 at our center. The nodules were assessed on typical ultrasound images using the CAD system and reviewed by 1 experienced radiologist. The radiologist stratified the risk of malignancy using the Thyroid Imaging Reporting and Data Systems (TIRADS) and the American Thyroid Association (ATA) guidelines...
December 29, 2017: Head & Neck
https://www.readbyqxmd.com/read/29279153/inter-exam-agreement-and-diagnostic-performance-of-the-korean-thyroid-imaging-reporting-and-data-system-for-thyroid-nodule-assessment-real-time-versus-static-ultrasonography
#4
Jung Min Bae, Soo Yeon Hahn, Jung Hee Shin, Eun Young Ko
OBJECTIVE: To investigate the inter-exam agreement for thyroid nodule between real-time ultrasonography (US) assessment and retrospective US interpretation and to compare the diagnostic performance between two methods by using the most recently published guidelines for the US-based management of thyroid nodules, the Korean Thyroid Imaging Reporting and Data System (K-TIRADS). METHODS: The study included 253 nodules in 238 patients for the inter-exam agreement and 201 nodules in 190 patients for the diagnostic performance...
January 2018: European Journal of Radiology
https://www.readbyqxmd.com/read/29260252/-functional-diagnostics-in-endocrinology
#5
REVIEW
C J Auernhammer, M Reincke
When investigating many endocrinological diseases, basal laboratory parameters are not sufficient to distinguish between physiological and pathological hormone secretion. Functional diagnostics plays a decisive role in this context. Stimulation and suppression tests are used depending on whether under- or over-function needs to be diagnosed. This review article discusses selected functional tests, each of which plays an important role in current guidelines. Indications and test principles, including their performance, reliability, and limitations, are discussed...
December 19, 2017: Der Internist
https://www.readbyqxmd.com/read/29243502/evidence-based-management-of-incidental-focal-uptake-of-fluorodeoxyglucose-on-pet-ct
#6
Deborah Pencharz, Malavika Nathan, Thomas L Wagner
Focal incidental uptake, with or without CT abnormalities, is a common finding on FDG PET/CT and evidence based management for this type of uptake is lacking. This article reviews the evidence on focal incidental uptake including the incidence of malignancy, differential diagnosis and imaging criteria which can be used to further characterise it. The article focusses on PET rather than CT criteria. The strength of the evidence base is highly variable ranging from systematic reviews and meta-analyses to a virtual absence of evidence...
December 15, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/29181988/diagnostic-performances-and-interobserver-agreement-according-to-observer-experience-a-comparison-study-using-three-guidelines-for-management-of-thyroid-nodules
#7
Jieun Koh, Soo-Yeon Kim, Hye Sun Lee, Eun-Kyung Kim, Jin Young Kwak, Hee Jung Moon, Jung Hyun Yoon
Background The differences regarding categorization of thyroid nodules among different guidelines may affect the diagnostic performances and agreement among observers. Purpose To compare the diagnostic performances and agreements between observers with various degree of experience when applying different guidelines for stratifying thyroid nodules using suspicious ultrasonography (US) features. Material and Methods This retrospective study included 370 thyroid nodules (≥10 mm). Four observers, grouped as experienced and inexperienced, evaluated the US features and made final assessments according to the Kim criteria, Thyroid Imaging Reporting and Data System (TIRADS) by Kwak et al...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/29179856/learning-curve-of-thyroid-fine-needle-aspiration-biopsy
#8
Manuel Penín, M Ángeles Martín, Beatriz San Millán, Juana García
BACKGROUND: Fine-needle aspiration biopsy (FNAB) is the reference procedure for thyroid nodule evaluation. Its main limitation are inadequate samples, which should be less than 20%. OBJECTIVE: To analyze the learning curve of the procedure by comparing the results of a non-experienced endocrinologist (endocrinologist 2) to those of an experienced one (endocrinologist 1). MATERIAL AND METHODS: Sixty FNABs were analyzed from February to June 2016...
December 2017: Endocrinología, Diabetes y Nutrición
https://www.readbyqxmd.com/read/29167761/european-thyroid-association-guidelines-for-ultrasound-malignancy-risk-stratification-of-thyroid-nodules-in-adults-the-eu-tirads
#9
Gilles Russ, Steen J Bonnema, Murat Faik Erdogan, Cosimo Durante, Rose Ngu, Laurence Leenhardt
Thyroid ultrasound (US) is a key examination for the management of thyroid nodules. Thyroid US is easily accessible, noninvasive, and cost-effective, and is a mandatory step in the workup of thyroid nodules. The main disadvantage of the method is that it is operator dependent. Thyroid US assessment of the risk of malignancy is crucial in patients with nodules, in order to select those who should have a fine needle aspiration (FNA) biopsy performed. Due to the pivotal role of thyroid US in the management of patients with nodules, the European Thyroid Association convened a panel of international experts to set up European guidelines on US risk stratification of thyroid nodules...
September 2017: European Thyroid Journal
https://www.readbyqxmd.com/read/29161789/current-status-of-thyroid-fine-needle-aspiration-practice-in-thailand
#10
REVIEW
Somboon Keelawat, Samreung Rangdaeng, Supinda Koonmee, Tikamporn Jitpasutham, Andrey Bychkov
Thyroid carcinoma is one of the leading malignancies in Thailand increasingly prevalent in the female population. Fine-needle aspiration (FNA) cytology is a widely used diagnostic tool for evaluation of thyroid nodules and thyroid cancer. Thyroid FNA is a routine procedure universally performed in Thai hospitals by a variety of clinical specialists. Manual guidance is the first-line choice complemented by ultrasound assistance in selected cases. Despite national guidelines recommendations, the diagnostic criteria and terminology of the Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) was slowly adopted in the local settings...
November 2017: Journal of Pathology and Translational Medicine
https://www.readbyqxmd.com/read/29160163/cancer-risk-associated-with-nuclear-atypia-in-cytologically-indeterminate-thyroid-nodules-a-systematic-review-and-meta-analysis
#11
Pablo Valderrabano, Laila Khazai, Zachary J Thompson, Susan C Sharpe, Valentina D Tarasova, Kristen J Otto, Julie E Hallanger-Johnson, J Trad Wadsworth, Bruce M Wenig, Christine H Chung, Barbara A Centeno, Bryan McIver
BACKGROUND: Indeterminate categories of thyroid cytopathology (categories B-III and B-IV of the Bethesda system) are integrated by a heterogeneous spectrum of cytological scenarios that are generally clustered for analysis and management recommendations. It has been suggested that aspirates exhibiting nuclear atypia have a higher risk of malignancy. This study aimed to assess whether cytologically indeterminate thyroid nodules with nuclear atypia have a significantly higher cancer risk than those without nuclear atypia...
December 21, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/29137085/current-trends-of-practical-issues-concerning-micropapillary-thyroid-carcinoma-the-korean-society-of-thyroid-head-and-neck-surgery
#12
Yoon Se Lee, Byung-Joo Lee, Hyun Joon Hong, Kang-Dae Lee
Although several thyroid associations have published various guidelines, controversies especially in cases of micropapillary thyroid cancer (MPTC) still exist. This survey was designed to collect information about diagnostic tests and treatments performed on patients with MPTC and help identify current trends in thyroid surgery.We developed questionnaires about the management methods for MPTC, which were used to identify factors related to indications of fine needle aspiration (FNA), type of surgery, and central lymph node dissection (CLND)...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29108488/validation-of-three-scoring-risk-stratification-models-for-thyroid-nodules
#13
Su Min Ha, Hye Shin Ahn, Jung Hwan Baek, Hwa Young Ahn, Yun Jae Chung, Bo Youn Cho, Sung Bin Park
BACKGROUND: To minimize potential harm from overuse of fine-needle aspiration, Thyroid Imaging Reporting and Data Systems (TIRADSs) were developed for thyroid nodule risk stratification. The purpose of this study was to perform validation of three scoring risk stratification models for thyroid nodules using ultrasonography features, a web-based malignancy risk stratification system at website (http://www.gap.pe.kr/thyroidnodule.php) and those developed by the Korean Society of Thyroid Radiology (KSThR) and the American College of Radiology (ACR)...
November 6, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/29094782/thyroid-fna-cytology-in-asian-practice-active-surveillance-for-indeterminate-thyroid-nodules-reduces-overtreatment-of-thyroid-carcinomas
#14
REVIEW
K Kakudo, M Higuchi, M Hirokawa, S Satoh, C K Jung, A Bychkov
Although Asian thyroid practices have implemented the American Thyroid Association guidelines, significant deviations in actual risk of malignancy (ROM) have been reported. With review of the literature from Asia, the authors examine the underlining reasons for actual ROMs reported in Asia being so different from western practice based on the author's perspective. Although the most popular diagnostic system for thyroid cytology used in Asian countries is the Bethesda system, the Japan Thyroid Association published clinical guidelines, including a national reporting system for thyroid cytology, to adapt conservative clinical management (active surveillance and strict triage patients for surgery) for low-risk thyroid carcinomas...
November 2, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29094776/molecular-testing-of-braf-ras-and-tert-on-thyroid-fnas-with-indeterminate-cytology-improves-diagnostic-accuracy
#15
M Decaussin-Petrucci, F Descotes, L Depaepe, V Lapras, M-L Denier, F Borson-Chazot, J-C Lifante, J Lopez
OBJECTIVE: Liquid-based (LB)-FNA is widely recognized as a reliable diagnostic method to evaluate thyroid nodules. However, up to 30% of LB-FNA remain indeterminate according to the Bethesda system. Use of molecular biomarkers has been recommended to improve its pathological accuracy but implementation of these tests in clinical practice may be difficult. Here, we evaluated feasibility and performance of molecular profiling in routine practice by testing LB-FNA for BRAF, N/HRAS and TERT mutations...
November 2, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29091005/thyroid-nodules-with-nondiagnostic-cytologic-results-follow-up-management-using-ultrasound-patterns-based-on-the-2015-american-thyroid-association-guidelines
#16
Chae Jung Park, Eun-Kyung Kim, Hee Jung Moon, Jung Hyun Yoon, Vivian Youngjean Park, Jin Young Kwak
OBJECTIVE: The purpose of this study was to evaluate the malignancy rate of nodules with nondiagnostic cytologic results based on the American Thyroid Association (ATA) ultrasound (US) patterns and to suggest management guidelines for these nodules. MATERIALS AND METHODS: From January 2013 to December 2014, 441 nodules (≥ 1 cm) were found in 437 patients with nondiagnostic results of ultrasound (US)-guided fine-needle aspiration biopsy (nondiagnostic nodules)...
November 1, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29073758/the-use-of-fine-needle-aspiration-fna-cytology-in-patients-with-thyroid-nodules-in-asia-a-brief-overview-of-studies-from-the-working-group-of-asian-thyroid-fna-cytology
#17
REVIEW
Chan Kwon Jung, SoonWon Hong, Andrey Bychkov, Kennichi Kakudo
Ultrasound-guided fine-needle aspiration (FNA) cytology is the most widely used screening and diagnostic method for thyroid nodules. Although Western guidelines for managing thyroid nodules and the Bethesda System for Reporting Thyroid Cytopathology are widely available throughout Asia, the clinical practices in Asia vary from those of Western countries. Accordingly, the Working Group of Asian Thyroid FNA Cytology encouraged group members to publish their works jointly with the same topic. The articles in this special issue focused on the history of thyroid FNA, FNA performers and interpreters, training programs of cytopathologists and cytotechnicians, staining methods, the reporting system of thyroid FNA, quality assurance programs, ancillary testing, and literature review of their own country's products...
November 2017: Journal of Pathology and Translational Medicine
https://www.readbyqxmd.com/read/29044641/qualitative-and-semiquantitative-elastography-for-the-diagnosis-of-intermediate-suspicious-thyroid-nodules-based-on-the-2015-american-thyroid-association-guidelines
#18
Bo Ra Yang, Eun-Kyung Kim, Hee Jung Moon, Jung Hyun Yoon, Vivian Y Park, Jin Young Kwak
OBJECTIVES: To evaluate qualitative and semiquantitative elastography for the diagnosis of intermediate suspicious thyroid nodules based on the 2015 American Thyroid Association (ATA) guidelines. METHODS: Through a retrospective search of our institutional database, 746 solid thyroid nodules found on grayscale ultrasonography, strain elastography, and ultrasound-guided fine-needle aspiration between June and November 2009 were collected. Among them, 80 nodules from 80 patients with an intermediate suspicion of malignancy based on the 2015 ATA guidelines that were 10 mm or larger were recruited as the final study nodules...
October 16, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29044289/preoperative-diagnostics-in-differentiated-thyroid-carcinoma
#19
Philipp Seifert, Martin Freesmeyer
AIM: The preoperative diagnosis of differentiated thyroid carcinomas (DTC) is particularly challenging in view of the high prevalence of thyroid nodules in the general population. Incidental diagnosis of DTC, on the other hand, can lead to reoperations and increased risk of morbidity. This study aimed to assess the prediction value of preoperative DTC dignity assessment and it's impact on surgical approaches. METHODS: We retrospectively reviewed 107 cases of DTC and subdivided them in three groups based on the preoperative dignity assessment: suspected malignancy (SM), unclear dignity (UD), and incidental findings (IF)...
October 18, 2017: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/29039253/stakeholder-driven-quality-improvement-a-compelling-force-for-clinical-practice-guidelines
#20
Richard M Rosenfeld, Peter C Wyer
Clinical practice guideline development should be driven by rigorous methodology, but what is less clear is where quality improvement enters the process: should it be a priority-guiding force, or should it enter only after recommendations are formulated? We argue for a stakeholder-driven approach to guideline development, with an overriding goal of quality improvement based on stakeholder perceptions of needs, uncertainties, and knowledge gaps. In contrast, the widely used topic-driven approach, which often makes recommendations based only on randomized controlled trials, is driven by epidemiologic purity and evidence rigor, with quality improvement a downstream consideration...
October 1, 2017: Otolaryngology—Head and Neck Surgery
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