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Arthroplasty infection staphylococcus.aureus

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https://www.readbyqxmd.com/read/29715226/development-and-evaluation-of-a-preoperative-risk-calculator-for-periprosthetic-joint-infection-following-total-joint-arthroplasty
#1
Timothy L Tan, Mitchell G Maltenfort, Antonia F Chen, AliSina Shahi, Carlos A Higuera, Marcelo Siqueira, Javad Parvizi
BACKGROUND: Preoperative identification of patients at risk for periprosthetic joint infection (PJI) following total hip arthroplasty (THA) or total knee arthroplasty (TKA) is important for patient optimization and targeted prevention. The purpose of this study was to create a preoperative PJI risk calculator for assessing a patient's individual risk of developing (1) any PJI, (2) PJI caused by Staphylococcus aureus, and (3) PJI caused by antibiotic-resistant organisms. METHODS: A retrospective review was performed of 27,717 patients (12,086 TKAs and 31,167 THAs), including 1,035 with confirmed PJI, who were treated at a single institution from 2000 to 2014...
May 2, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29695923/antibiotic-sensitivities-of-coagulase-negative-staphylococci-and-staphylococcus-aureus-in-hip-and-knee-periprosthetic-joint-infections-does-this-differ-if-patients-meet-the-international-consensus-meeting-criteria
#2
Elena De Vecchi, David A George, Carlo L Romanò, Fabrizio E Pregliasco, Roberto Mattina, Lorenzo Drago
Introduction: Coagulase-negative staphylococci (CoNS) are the main pathogens responsible for prosthetic joint infections (PJIs). As normal inhabitants of human skin, it is often difficult to define if they are contaminants, or if they have an active role in initiating infection. This study aims to evaluate differences in CoNS organisms ( Staphylococcus hominis, Staphylococcus capitis , Staphylococcus haemolyticus , Staphylococcus warneri) and Staphylococcus aureus in terms of isolation rate and antimicrobial susceptibility from patients who met the International Consensus Meeting (ICM) criteria for PJIs and those who did not...
2018: Infection and Drug Resistance
https://www.readbyqxmd.com/read/29658483/bacteriology-and-risk-factors-associated-with-periprosthetic-joint-infection-after-primary-total-knee-arthroplasty-retrospective-study-of-2543-cases
#3
K T Siu, F Y Ng, P K Chan, H Ch Fu, C H Yan, K Y Chiu
INTRODUCTION: Periprosthetic joint infection after total knee arthroplasty is a serious complication. This study aimed to identify risk factors and bacteriological features associated with periprosthetic joint infection after primary total knee arthroplasty performed at a teaching hospital. METHODS: We reviewed 2543 elective primary total knee arthroplasties performed at our institution from 1993 to 2013. Data were collected from the Hong Kong Hospital Authority's Clinical Data Analysis and Reporting System, the Infection Control Team, and the joint replacement division registry...
April 2018: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/29627258/does-prior-failed-debridement-compromise-the-outcome-of-subsequent-two-stage-revision-done-for-periprosthetic-joint-infection-following-total-knee-arthroplasty
#4
Ashok Rajgopal, Inayat Panda, Arun Rao, Vivek Dahiya, Himanshu Gupta
BACKGROUND: There has been a debate regarding the outcomes of 2-stage revision total knee arthroplasty (TKA) when debridement, antibiotics, irrigation, and implant retention (DAIR) had been carried out previously. The purpose of this study is to evaluate the influence of prior failed DAIR (F-DAIR) on the outcomes of 2-stage revision TKA done for periprosthetic joint infection (PJI). METHODS: This is a retrospective study of a consecutive series of 184 knees that completed 2-stage revision TKA for PJI, operated by a single surgeon between January 2000 and July 2011...
March 9, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29610010/high-rate-of-positive-cultures-in-patients-referred-with-antibiotic-spacers-as-part-of-2-stage-exchange
#5
Kevin I Perry, Robert C Sproul, Rafael J Sierra, Matthew P Abdel, Thomas K Fehring, Arlen D Hanssen
BACKGROUND: Two-stage exchange for periprosthetic joint infection (PJI) in total knee arthroplasty (TKA) remains the gold standard treatment in North America. Occasionally, patients with knee PJI are referred for definitive management after resection and antibiotic spacer placement. Currently, little literature exists to suggest how these patients should be managed. The purpose of this study is to report the clinical outcomes of these patients. METHODS: We retrospectively identified 54 patients (54 knees) from 2000 to 2012 treated for PJI with initial TKA resection and spacer placement performed somewhere other than the definitive treatment center...
February 21, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29600202/late-and-vague-presentation-of-septic-arthritis-of-hip-in-a-ivdrug-abuser
#6
Anantha Krishnan Raghupathi, Avinash Joshi
Introduction: Septic arthritis of the hip is a rare entity in acute presentation of hip pain in adults. Even though hip is the second most commonly affected joint, adult patients with septic arthritis not related to a surgical procedure represent <0.00001% of total acute admissions. Case Report: We present a 32-year-old female intravenous drug abuser, positive for Hepatitis B and C who had started to inject her femoral veins 2 years ago. She presented with a 10 weeks history of radiating pain in the leg which was full, constant and diffuse in nature with hip stiffness...
November 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/29555488/assessment-of-theatre-shoe-contamination-in-an-orthopaedic-theatre
#7
K Clesham, P R Ryan, C G Murphy
Prosthetic joint infection (PJI) is a devastating complication of arthroplasty. Numerous protocols reduce potential risk for PJI peri-operatively, but none exist for the management of theatre shoes. Our aim was to assess for bacteria known to cause prosthetic infection on theatre shoes. Forty theatre shoes were analysed; there were coagulase-negative staphylococci on 65% (N = 25), meticillin-susceptible Staphylococcus aureus on 40% (N = 16), and meticillin-resistant S. aureus on 25% (N = 10). Amount of blood spatter correlated poorly with microbial contamination...
March 16, 2018: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29529700/articulating-spacers-as-a-modified-one-stage-revision-total-knee-arthroplasty-a-preliminary-analysis
#8
Ahmed Siddiqi, Nicole E George, Peter B White, Bartlomiej W Szczech, John V Thompson, Jennifer I Etcheson, Chukwuweike U Gwam, Alexander T Caughran, Ronald E Delanois, James Nace
INTRODUCTION: Periprosthetic joint infection (PJI) following primary total knee arthroplasty (TKA) is a challenging complication for surgeons and patients alike. Although two-stage revision arthroplasty remains the gold standard PJI management in the United States, one-stage revision has had success in many parts of Europe. The aim of this study was to retrospectively review: 1) ultimate treatment success; 2) necessary antibiotic duration; 3) change in knee range of motion (ROM); and 4) final Knee Society Scores (KSS) in a case series of patients managed with retention of articulating antibiotic spacers following PJI...
March 12, 2018: Surgical Technology International
https://www.readbyqxmd.com/read/29529667/late-reinfection-may-recur-more-than-5-years-after-reimplantation-of-tha-and-tka-analysis-of-pathogen-factors
#9
Kevin L Garvin, Ryan E Miller, Todd M Gilbert, Anthony M White, Elizabeth R Lyden
BACKGROUND: Two-stage reimplantation has consistently yielded high rates of success for patients with chronic prosthetic joint infection, although results more than 5 years after reimplantation are not commonly reported. Numerous factors may contribute to the risk of reinfection, although these factors-as well as the at-risk period after reimplantation-are not well characterized. QUESTIONS/PURPOSES: (1) What is the risk of reinfection after reimplantation for prosthetic joint infection at a minimum of 5 years? (2) Is the bacteriology of the index infection associated with late reinfection? (3) Is the presence of bacteria at the time of reimplantation associated with late reinfection? METHODS: Between 1995 and 2010, we performed 97 two-stage revisions in 93 patients for prosthetic joint infection of the hip or knee, and all are included in this retrospective study...
February 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29510950/the-cost-effectiveness-of-preoperative-staphylococcus-aureus-screening-and-decolonization-in-total-joint-arthroplasty
#10
Yehuda E Kerbel, Anisha R Sunkerneni, Gregory J Kirchner, John P Prodromo, Vincent M Moretti
BACKGROUND: This article presents a break-even analysis for preoperative Staphylococcus aureus colonization screening and decolonization protocols in total hip arthroplasty (THA) and total knee arthroplasty (TKA). METHODS: Protocol costs, baseline infection rates after arthroplasty, and average revision costs were obtained from institutional records and the literature. The break-even analysis determined the absolute risk reduction (ARR) in infection rate required for cost-effectiveness...
January 31, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29506927/cost-efficacy-of-methicillin-resistant-staphylococcus-aureus-decolonization-with-intranasal-povidone-iodine
#11
G Ryan Rieser, Joseph T Moskal
BACKGROUND: With increasing rates of virulent drug resistant organisms, MRSA (methicillin-resistant Staphylococcus aureus) decolonization has been demonstrated to decrease infection rates. Recent research has shown the antiseptic povidone-iodine to be equally effective and potentially cost saving compared to intranasal mupirocin. This study's purpose is to evaluate the incidence of MRSA colonization in a more rural community-based population, rates of infection on a mupirocin decolonization protocol, and develop a cost analysis model to compare costs of utilizing povidone-iodine...
January 31, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29503100/the-management-of-infected-elbow-arthroplasty-by-two-stage-revision
#12
Will B J Rudge, Kelechi Eseonu, Matthew Brown, Simon Warren, Addie Majed, Ian L Bayley, Simon M Lambert, Deborah Higgs, Mark Falworth
BACKGROUND: Deep prosthetic infection is a potentially devastating complication after total elbow arthroplasty, with an incidence of up to 12%. This study examined the demographics, microbiologic profile, and outcomes of infected total elbow arthroplasty treated with 2-stage revision in a tertiary referral unit. METHODS: We identified 19 consecutive patients (mean age, 65 years) undergoing revision arthroplasty for deep prosthetic infection. All patients underwent a first-stage procedure with removal of implants, débridement, and insertion of an antibiotic-loaded cement spacer, followed by at least 6 weeks of intravenous antibiotics...
May 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29502963/changes-in-antibiotic-susceptibility-of-staphylococcus-aureus-between-the-stages-of-2-stage-revision-arthroplasty
#13
Jaiben George, Jared M Newman, Alison K Klika, Evan M Miller, Timothy L Tan, Javad Parvizi, Carlos A Higuera
BACKGROUND: Staphylococcus aureus is the predominant cause of periprosthetic joint infection (PJI) and can persist at the time of planned second stage of 2-stage revision arthroplasty, despite antibiotic cement spacer insertion and parenteral antibiotic therapy. Given the rapid emergence of antibiotic resistance, it is important to determine whether the antibiotic susceptibility of microorganisms changes between the stages of a 2-stage revision. METHODS: A total of 1614 2-stage revision hip/knee arthroplasties performed for PJI at 2 academic institutions from 2000 to 2015 were identified...
March 1, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29450105/infection-versus-hematoma-following-surgical-treatment-of-proximal-femoral-fractures-in-geriatric-patients
#14
Franz Müller, Michael Galler, Christina Roll, Bernd Füchtmeier
Introduction: The surgical treatment of proximal femoral fractures predominantly involves geriatric patients and is associated with high morbidity and mortality. However, analyses on postoperative infections or hematoma are rare. Methods: Patients requiring surgical revision due to infection (n = 90) or hematoma (n = 77) in the postoperative phase were identified from an electronic database of 2000 consecutive patients surgically treated for proximal femoral fractures between 2006 and 2014...
2018: Geriatric Orthopaedic Surgery & Rehabilitation
https://www.readbyqxmd.com/read/29395724/risk-factors-for-staphylococcus-aureus-nasal-colonization-in-joint-arthroplasty-patients
#15
Amanda L Walsh, Adam C Fields, James D Dieterich, Darwin D Chen, Michael J Bronson, Calin S Moucha
BACKGROUND: Several studies have shown that Staphylococcus aureus (S aureus) nasal colonization is associated with surgical site infection and that preoperative decolonization can reduce infection rates. Up to 30% of joint arthroplasty patients have positive S aureus nasal swabs. Patient risk factors for colonization remain largely unknown. The aim of this study was to determine whether there is a specific patient population at increased risk of S aureus nasal colonization. METHODS: This study is a retrospective review of 716 patients undergoing hip or knee arthroplasty beginning in 2011...
May 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29383856/detecting-the-presence-of-bacterial-dna-and-rna-by-polymerase-chain-reaction-to-diagnose-suspected-periprosthetic-joint-infection-after-antibiotic-therapy
#16
Xin-Yu Fang, Wen-Bo Li, Chao-Fan Zhang, Zi-da Huang, Hui-Yi Zeng, Zheng Dong, Wen-Ming Zhang
OBJECTIVE: To explore the diagnostic efficiency of DNA-based and RNA-based quantitative polymerase chain reaction (qPCR) analyses for periprosthetic joint infection (PJI). METHODS: To determine the detection limit of DNA-based and RNA-based qPCR in vitro, Staphylococcus aureus and Escherichia coli strains were added to sterile synovial fluid obtained from a patient with knee osteoarthritis. Serial dilutions of samples were analyzed by DNA-based and RNA-based qPCR...
February 2018: Orthopaedic Surgery
https://www.readbyqxmd.com/read/29330346/underestimation-of-staphylococcus-aureus-mrsa-and-mssa-carriage-associated-with-standard-culturing-techniques-one-third-of-carriers-missed
#17
S T J Tsang, M P McHugh, D Guerendiain, P J Gwynne, J Boyd, A H R W Simpson, T S Walsh, I F Laurenson, K E Templeton
OBJECTIVES: Nasal carriers of Staphylococcus (S.) aureus ( MRSA and MSSA ) have an increased risk for healthcare-associated infections. There are currently limited national screening policies for the detection of S. aureus despite the World Health Organization's recommendations. This study aimed to evaluate the diagnostic performance of molecular and culture techniques in S. aureus screening, determine the cause of any discrepancy between the diagnostic techniques, and model the potential effect of different diagnostic techniques on S...
January 2018: Bone & Joint Research
https://www.readbyqxmd.com/read/29234644/prophylaxis-with-nasal-decolonization-in-patients-submitted-to-total-knee-and-hip-arthroplasty-systematic-review-and-meta-analysis
#18
REVIEW
David Sadigursky, Henrique Santos Pires, Saulo Américo Caldas Rios, Francisco Luiz Borja Rodrigues Filho, Gustavo Castro de Queiroz, Mateus Lemos Azi
Despite the evolution of the total knee and hip arthroplasty surgery, high postoperative complication rates in the short and long term still persist. Infection is one of the most challenging complications; due to its gravity and treatment difficulties, prophylaxis protocols have been created to decrease its incidence. The objective of this study was to evaluate the impact of the prophylaxis protocol for methicillin-resistant Staphylococcus aureus decolonization of the nares in patients previously identified by swab cultures, who were to be submitted to a total joint arthroplasty...
November 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/29107499/clinical-outcome-of-massive-endoprostheses-used-for-managing-periprosthetic-joint-infections-of-the-hip-and-knee
#19
Abtin Alvand, George Grammatopoulos, Floris de Vos, Matthew Scarborough, Ben Kendrick, Andrew Price, Roger Gundle, Duncan Whitwell, William Jackson, Adrian Taylor, Christopher L M H Gibbons
BACKGROUND: Endoprosthetic replacement (EPR) is an option for management of massive bone loss resulting from infection around failed lower limb implants. The aim of this study is to determine the mid-term outcome of EPRs performed in the treatment of periprosthetic joint infection (PJI) and infected failed osteosyntheses around the hip and knee joint and identify factors that influence it. METHODS: We retrospectively reviewed all hip and knee EPRs performed between 2007 and 2014 for the management of chronic infection following complex arthroplasty or fracture fixation...
March 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29092997/the-orthopaedic-manifestation-and-outcomes-of-methicillin-sensitive-staphylococcus-aureus-septicaemia
#20
D Makki, T Elgamal, P Evans, D Harvey, G Jackson, S Platt
AIMS: The aim of this paper was to present the clinical features of patients with musculoskeletal sources of methicillin-sensitive Staphylococcus aureus (MSSA) septicaemia. PATIENTS AND METHODS: A total of 137 patients presented with MSSA septicaemia between 2012 and 2015. The primary source of infection was musculoskeletal in 48 patients (35%). Musculoskeletal infection was considered the primary source of septicaemia when endocarditis and other obvious sources were excluded...
November 2017: Bone & Joint Journal
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