Brandon M Roberts, Alyssa V Geddis, Alexandra Ciuciu, Marinaliz Reynoso, Nikhil Mehta, Alyssa N Varanoske, Alyssa M Kelley, Raymond J Walker, Rigoberto Munoz, Alexander L Kolb, Jeffery S Staab, Marshall A Naimo, Ryan E Tomlinson
Acetaminophen (ACE) is a widely used analgesic and antipyretic drug with various applications, from pain relief to fever reduction. Recent studies have reported equivocal effects of habitual ACE intake on exercise performance, muscle growth, and risks to bone health. Thus, this study aimed to assess the impact of a 6-week, low-dose ACE regimen on muscle and bone adaptations in exercising and non-exercising rats. Nine-week-old Wistar rats (n = 40) were randomized to an exercise or control (no exercise) condition with ACE or without (placebo)...
April 15, 2024: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology