Eric Genaro Salmerón-Bárcenas, Ana Elvira Zacapala-Gómez, Francisco Israel Torres-Rojas, Verónica Antonio-Véjar, Pedro Antonio Ávila-López, Christian Johana Baños-Hernández, Hober Nelson Núñez-Martínez, Roberto Dircio-Maldonado, Dinorah Nashely Martínez-Carrillo, Julio Ortiz-Ortiz, Hilda Jiménez-Wences
Breast Cancer (BC) was the most common female cancer in incidence and mortality worldwide in 2020. Similarly, BC was the top female cancer in the USA in 2022. Risk factors include earlier age at menarche, oral contraceptive use, hormone replacement therapy, high body mass index, and mutations in BRCA 1/2 genes, among others. BC is classified into Luminal A, Luminal B, HER2-like, and Basal-like subtypes. These BC subtypes present differences in gene expression signatures, which can impact clinical behavior, treatment response, aggressiveness, metastasis, and survival of patients...
December 24, 2023: International Journal of Molecular Sciences