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Cervical length screening

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https://www.readbyqxmd.com/read/28540576/cervical-length-dynamics-in-triplet-pregnancies-a-retrospective-cohort-study
#1
Sophie Pils, Stephanie Springer, Verena Wehrmann, Kinga Chalubinski, Johannes Ott
PURPOSE: To review our experience with a screening program that included sequential cervical length measurements in our large population of triplet pregnancies. METHODS: Seventy-eight triplet pregnancies were retrospectively included. Cervical length measurements were performed by transvaginal ultrasound in 2-week intervals from week 16 + 0 onwards in a tertiary-care center in Vienna. The main outcome measurement was preterm delivery prior to 32 + 0 weeks of gestation...
May 24, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28491092/can-transabdominal-scan-predict-a-short-cervix-by-transvaginal-scan
#2
Jayaraman Mavila Nambiar, Muralidhar Vaman Pai, Arevidya Reddy, Pratap Kumar
Background. To determine whether transabdominal screening can be used to screen women with short cervix on transvaginal scan. Methods. The study was done between 18 and 20 weeks of gestation. Transabdominal scan was done and cervical length was measured. Transvaginal scan was also done and cervical length was measured. An attempt was made to find out whether transabdominal scan be used to predict a cervical length of 25 mm by transvaginal scan. Results. In our study the cut-off for transabdominal scan for detecting a short cervix of 25 mm by transvaginal scan was 29 mm...
2017: Obstetrics and Gynecology International
https://www.readbyqxmd.com/read/28486361/universal-cervical-length-screening-and-antenatal-corticosteroid-timing
#3
Nicole Sahasrabudhe, Catherine Igel, Ghislaine C Echevarria, Peʼer Dar, Diana Wolfe, Peter S Bernstein, Robert Angert, Ashlesha Dayal, Patience Gallagher, Mara Rosner
OBJECTIVE: To evaluate the relationship between universal transvaginal screening for short cervical length in the second trimester and the timing of antenatal corticosteroids. METHODS: We performed a retrospective cohort study of patients with nonanomalous singleton gestations and spontaneous preterm birth between 24 and 34 weeks of gestation after the initiation of a universal transvaginal cervical length screening program between October 2012 and August 2015. Our primary outcome was antenatal corticosteroid administration to a delivery interval of fewer than 7 days...
June 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28471690/the-evolving-concept-of-sle-comorbidities
#4
Luis Alonso González, Graciela S Alarcón
The survival of SLE patients has improved significantly over the past few decades placing them at increased risk of cardiovascular disease (CVD), malignancies, and osteoporosis, among other comorbidities. The aim of this review was to assess the incidence and prevalence of comorbidities in these patients as well as their prevention and treatment focusing in CVD, malignancies and osteoporosis. Areas covered: We focused on CVD, malignancies and osteoporosis as SLE comorbidities. A literature search (PubMed database) was performed using the words "comorbidities", "cardiovascular disease", "osteoporosis", "malignancy", "cancer" and "lupus" between January 1976 and December 2016...
May 4, 2017: Expert Review of Clinical Immunology
https://www.readbyqxmd.com/read/28451496/carotid-artery-injury-in-anterior-cervical-spine-surgery-multicenter-cohort-study-and-literature-review
#5
Roger Härtl, Marjan Alimi, Mohamed Abdelatif Boukebir, Connor D Berlin, Rodrigo Navarro-Ramirez, Paul M Arnold, Michael G Fehlings, Thomas E Mroz, K Daniel Riew
STUDY DESIGN: Retrospective study and literature review. OBJECTIVE: To provide more comprehensive data about carotid artery injury (CAI) or cerebrovascular accident (CVA) related to anterior cervical spine surgery. METHODS: We conducted a retrospective, multicenter, case series study involving 21 high-volume surgical centers from the AOSpine North America Clinical Research Network. Medical records of 17 625 patients who went through cervical spine surgery (levels from C2 to C7) between January 1, 2005, and December 31, 2011, were analyzed...
April 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28451487/epidemiology-and-outcomes-of-vertebral-artery-injury-in-16%C3%A2-582-cervical-spine-surgery-patients-an-aospine-north-america-multicenter-study
#6
Wellington K Hsu, Abhishek Kannan, Harry T Mai, Michael G Fehlings, Zachary A Smith, Vincent C Traynelis, Ziya L Gokaslan, Alan S Hilibrand, Ahmad Nassr, Paul M Arnold, Thomas E Mroz, Mohamad Bydon, Eric M Massicotte, Wilson Z Ray, Michael P Steinmetz, Gabriel A Smith, Jonathan Pace, Mark Corriveau, Sungho Lee, Robert E Isaacs, Jeffrey C Wang, Elizabeth L Lord, Zorica Buser, K Daniel Riew
STUDY DESIGN: A multicenter retrospective case series was compiled involving 21 medical institutions. Inclusion criteria included patients who underwent cervical spine surgery between 2005 and 2011 and who sustained a vertebral artery injury (VAI). OBJECTIVE: To report the frequency, risk factors, outcomes, and management goals of VAI in patients who have undergone cervical spine surgery. METHODS: Patients were evaluated on the basis of condition-specific functional status using the Neck Disability Index (NDI), modified Japanese Orthopaedic Association (mJOA) score, the Nurick scale, and the 36-Item Short-Form Health Survey (SF-36)...
April 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28393580/second-trimester-cervical-length-and-outcomes-of-induction-of-labor-at-term
#7
Rupsa C Boelig, Anju Suhag, Juliana Guarente, Kelly Orzechowski, Vincenzo Berghella
OBJECTIVE: To evaluate whether second-trimester cervical length (CL) is associated with induction of labor (IOL) outcomes. METHODS: Retrospective cohort study of nulliparous singletons undergoing CL screening at 18 0/7-23 6/7 weeks from 1/1/2012 to 12/31/2013. Women induced at term (≥37 weeks) were included. Primary outcome was vaginal delivery (VD) within 24 h. The effect of CL on outcomes was assessed by incidence across CL quartiles and a receiver operating characteristics (ROC) curve...
April 10, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28383102/risk-stratification-in-cervical-cancer-screening-by-complete-screening-history-applying-bioinformatics-to-a-general-screening-population
#8
Nicholas Baltzer, Karin Sundström, Jan F Nygård, Joakim Dillner, Jan Komorowski
Women screened for cervical cancer in Sweden are currently treated under a one-size-fits-all programme, which has been successful in reducing the incidence of cervical cancer but does not use all of the participants' available medical information. This study aimed to use women's complete cervical screening histories to identify diagnostic patterns that may indicate an increased risk of developing cervical cancer. A nationwide case-control study was performed where cervical cancer screening data from 125,476 women with a maximum follow-up of 10 years were evaluated for patterns of SNOMED diagnoses...
April 6, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28370687/mid-trimester-sonographic-cervical-consistency-index-to-predict-spontaneous-preterm-birth-in-a-low-risk-population
#9
Núria Baños, Clara Murillo-Bravo, Carla Julià, Federico Migliorelli, Alvaro Perez-Moreno, Jose Ríos, Eduard Gratacos, Lil Valentin, Montse Palacio
OBJECTIVES: To estimate the ability of mid-trimester sonographic Cervical Consistency Index (CCI) to predict spontaneous preterm birth (sPTB) in low-risk pregnancies and to compare its performance with mid-trimester sonographic cervical length (CL). METHODS: This is a prospective cohort study including women with singleton pregnancies examined with ultrasound at 19 + 0 to 24 + 6 gestational weeks. All underwent transvaginal ultrasound examination of the cervix, but CCI and CL were measured off-line only in women without risk factors for sPTB...
March 31, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28364196/citizenship-length-of-stay-and-screening-for-breast-cervical-and-colorectal-cancer-in-women-2000-2010
#10
Patricia Y Miranda, Nengliang Yao, S Amy Snipes, Rhonda BeLue, Eugene Lengerich, Marianne M Hillemeier
BACKGROUND: Two factors jointly account for significant gaps in access to health care among immigrants who are present in the U.S.-legal status, and length of residence. The objective of this study is to examine the association between citizenship and length of residence in the U.S. and cancer screening (breast, cervical, and colorectal) among women. METHODS: We analyzed 11 years (2000-2010) of consolidated data from the Medical Expenditure Panel Survey linked with the National Health Interview Survey...
March 31, 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28349969/minoxidil-is-a-potential-neuroprotective-drug-for-paclitaxel-induced-peripheral-neuropathy
#11
Yi-Fan Chen, Li-Hsien Chen, Yu-Min Yeh, Pei-Ying Wu, Yih-Fung Chen, Lian-Yun Chang, Jang-Yang Chang, Meng-Ru Shen
Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of cancer treatment. No medication has been shown to be effective in the treatment of CIPN. This study aims to integrate the image-based high-content screening, mouse behavior models and mechanistic cell-based assays to discover potential neuroprotective drugs. Among screened compounds, minoxidil showed the most potent neuroprotective effect against paclitaxel, with regard to neurite outgrowth of dorsal root ganglia (DRG). Minoxidil protected mice from thermal insensitivity and alleviated mechanical allodynia in paclitaxel-treated mice...
March 28, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28320241/implementation-of-a-universal-cervical-length-screening-program-identifying-factors-associated-with-decline-rates
#12
Jeny Ghartey, Neda Ghaffari, Lisa D Levine, Nadav Schwartz, Celeste P Durnwald
PURPOSE: Cervical length (CL) measurement is now accepted as a screening strategy for identifying women at risk for preterm birth (PTB). However, patient acceptability may limit its implementation. Our objective was to identify characteristics associated with women who decline this screening. MATERIALS AND METHODS: This is a secondary analysis of a prospective cohort study of women offered UCL screening from January 2012-June 2012. Women with a singleton gestation 18 0/7-23 6/7 weeks at the time of anatomy scan were included...
March 20, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28295722/cerclage-for-short-cervix-on-ultrasound-in-singleton-gestations-without-prior-spontaneous-preterm-birth-a-systematic-review-and-meta-analysis-of-trials-using-individual-patient-level-data
#13
REVIEW
Vincenzo Berghella, Andrea Ciardulli, Orion A Rust, Meekai To, Katsufumi Otsuki, Sietske Althuisius, Kypros Nicolaides, Amanda Roman, Gabriele Saccone
OBJECTIVE: The aim of this systematic review and meta-analysis was to quantify the efficacy of cervical cerclage in preventing preterm birth (PTB) in asymptomatic singleton pregnancies with a mid-trimester short transvaginal ultrasound cervical length (TVU CL) and without prior spontaneous PTB. METHODS: Electronic databases were searched from inception of each database until February 2017. No language restrictions were applied. We included all randomized controlled trials (RCTs) of asymptomatic singleton pregnancies without prior spontaneous PTB screened with TVU CL, found to have a midtrimester short CL <25 mm, and then randomized to management with either cerclage (i...
March 10, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28295170/implementing-universal-cervical-length-screening-in-asymptomatic-women-with-singleton-pregnancies-challenges-and-opportunities
#14
Michelle K Pedretti, Brenda M Kazemier, Jan E Dickinson, Ben W J Mol
Cervical length (CL) screening has been successfully utilised to identify asymptomatic women, with a singleton pregnancy, at risk of preterm birth (PTB), thereby providing an opportunity to offer interventions that may reduce that risk. Cervical length screening with ultrasound is most effectively performed with a transvaginal approach. Universal cervical length screening, encompassing all singleton pregnancies rather than restricting screening to those considered at increased risk of PTB, is currently not widely used, despite a growing body of evidence in support of its utility for PTB prevention...
April 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28291893/predictive-accuracy-of-serial-transvaginal-cervical-lengths-and-quantitative-vaginal-fetal-fibronectin-levels-for-spontaneous-preterm-birth-among-nulliparous-women
#15
M Sean Esplin, Michal A Elovitz, Jay D Iams, Corette B Parker, Ronald J Wapner, William A Grobman, Hyagriv N Simhan, Deborah A Wing, David M Haas, Robert M Silver, Matthew K Hoffman, Alan M Peaceman, Steve N Caritis, Samuel Parry, Pathik Wadhwa, Tatiana Foroud, Brian M Mercer, Shannon M Hunter, George R Saade, Uma M Reddy
Importance: Spontaneous preterm birth is a leading cause of infant mortality. Prediction, largely based on prior pregnancy outcomes, is not possible in women pregnant for the first time. Objective: To assess the accuracy of universal screening to predict spontaneous preterm birth in nulliparous women using serial measurements of vaginal fetal fibronectin levels and cervical length. Design, Settings, and Participants: A prospective observational cohort study of nulliparous women with singleton pregnancies, from 8 clinical sites across the United States between October 2010 and May 2014...
March 14, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28282774/cervical-length-in-adolescents-versus-adults
#16
Jessica N Buck, Kelly M Orzechowski, Jason K Baxter, Vincenzo Berghella
PURPOSE: Two of the known risk factors for spontaneous preterm birth (sPTB) are short cervical length (CL) ≤ 25 mm and adolescence (≤19 years). Our objective was to evaluate whether adolescent women have a higher incidence of short CL compared to their 20-24 year old counterparts. MATERIALS AND METHODS: Retrospective cohort of nulliparous singleton gestations undergoing universal second trimester transvaginal ultrasound (TVU) CL screening between January 2012 and June 2013...
February 28, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28266156/re-cervical-length-screening-for-prevention-of-preterm-birth-in-singleton-pregnancy-with-threatened-preterm-labor-systematic-review-and-meta-analysis-of-randomized-controlled-trials-using-individual-patient-level-data-v-berghella-m-palacio-a-ness-z-alfirevic
#17
COMMENT
https://www.readbyqxmd.com/read/28170117/prevention-of-preterm-birth-with-pessary-in-twins-poppt-a-randomized-controlled-trial
#18
V Berghella, L Dugoff, J Ludmir
OBJECTIVE: To evaluate whether cervical pessary placement prevents preterm birth (PTB) in twin gestations with a short mid-trimester cervical length (CL) on transvaginal sonography (TVS). METHODS: This was a multicenter randomized controlled trial of asymptomatic women with a twin gestation and a TVS-CL of ≤ 30 mm at 18 + 0 to 27 + 6 weeks' gestation. TVS-CL was measured at the time of the fetal anatomy scan at 18 + 0 to 23 + 6 weeks and at subsequent scheduled ultrasound scans prior to 28 weeks...
May 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28166925/-is-universal-screening-for-cervical-length-among-singleton-pregnancies-with-no-history-of-preterm-birth-justified
#19
P Rozenberg
The ultrasonographic measurement of cervical length with a cutoff of 15mm is currently the best method to identify a group of asymptomatic women in the general population at risk of spontaneous preterm birth, especially among asymptomatic patients with a singleton pregnancy with no history of preterm birth. Cerclage and 17 alpha-hydroxyprogesterone caproate (17OHP-C) are ineffective to reduce the risk of preterm birth among asymptomatic patients with a short cervix in midtrimester. However, vaginal progesterone (200-mg capsules of micronized progesterone or gel containing 90mg progesterone) has been demonstrated effective in 2 large randomized trials to reduce the risk of preterm birth and possibly the composite morbidity and perinatal mortality associated among asymptomatic women with a short cervix in the general population screened by ultrasound of the cervix in midtrimester...
December 2016: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
https://www.readbyqxmd.com/read/28153653/prenatal-diagnosis-and-management-of-vasa-previa-in-twin-pregnancies-a%C3%A2-case-series-and%C3%A2-systematic-review
#20
REVIEW
Eric Jauniaux, Yaakov Melcer, Ron Maymon
BACKGROUND: Twin pregnancies are at higher risks of velamentous cord insertion and vasa previa. In vitro fertilization is an additional risk factor of abnormal cord insertion and thus the incidence of vasa previa is likely to increase over the next decades. OBJECTIVE: We sought to evaluate the role of ultrasound imaging in optimizing the management of twins diagnosed with vasa previa antenatally. STUDY DESIGN: We searched our database for twin pregnancies diagnosed with vasa previa and managed antenatally using measurements of cervical length and performed a systematic review of articles that correlated prenatal diagnosis of vasa previa in twins and pregnancy outcome...
January 30, 2017: American Journal of Obstetrics and Gynecology
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