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Cervical length screening

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https://www.readbyqxmd.com/read/27889000/not-transabdominal
#1
EDITORIAL
Adeeb Khalifeh, Vincenzo Berghella
Preterm birth remains a major cause of perinatal morbidity and mortality. A short cervix is strongly associated with spontaneous preterm birth. Professional organizations support cervical length screening for singleton gestations with a prior spontaneous preterm birth and second-trimester cervical length measurements between 16-24 weeks. All interventions used to decrease the risk of preterm birth in women with a short cervix are based on clinical trials that used transvaginal cervical length measurement, but transabdominal ultrasound has been shown to correlate well with transvaginal measurement in some observational studies...
December 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27888999/transabdominal-ultrasound-is-appropriate
#2
EDITORIAL
David Stamilio, Laura M Carlson
Preterm birth remains a major cause of perinatal morbidity and mortality. A short cervix is strongly associated with spontaneous preterm birth. Professional organizations support cervical length screening for singleton gestations with a prior spontaneous preterm birth and second-trimester cervical length measurements between 16-24 weeks. All interventions used to decrease the risk of preterm birth in women with a short cervix are based on clinical trials that used transvaginal cervical length measurement, but transabdominal ultrasound has been shown to correlate well with transvaginal measurement in some observational studies...
December 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27843353/prevention-of-preterm-delivery-current-challenges-and-future-prospects
#3
REVIEW
Maud D van Zijl, Bouchra Koullali, Ben Wj Mol, Eva Pajkrt, Martijn A Oudijk
Preterm birth (PTB), defined as delivery at <37 weeks of gestation, is the most important cause of neonatal morbidity and mortality. Therefore, preventing PTB is one of the main goals in obstetric care. In this review, we provide an overview of the current available literature on screening for risk factors for PTB and a summary of preventive strategies in both low-risk and high-risk women with singleton or multiple gestations. Furthermore, current challenges and future prospects on PTB are discussed. For an optimal prevention of PTB, risk stratification should be based on a combination of (maternal) risk factors, obstetric history, and screening tools...
2016: International Journal of Women's Health
https://www.readbyqxmd.com/read/27836377/-prevention-of-spontaneous-preterm-birth-excluding-preterm-premature-rupture-of-membranes-guidelines-for-clinical-practice%C3%A2-%C3%A2-text-of-the-guidelines-short-text
#4
L Sentilhes, M-V Sénat, P-Y Ancel, E Azria, G Benoist, J Blanc, G Brabant, F Bretelle, S Brun, M Doret, C Ducroux-Schouwey, A Evrard, G Kayem, E Maisonneuve, L Marcellin, S Marret, N Mottet, S Paysant, D Riethmuller, P Rozenberg, T Schmitz, H Torchin, B Langer
OBJECTIVES: To determine the measures to prevent spontaneous preterm birth (excluding preterm premature rupture of membranes)and its consequences. MATERIALS AND METHODS: The PubMed database, the Cochrane Library and the recommendations from the French and foreign obstetrical societies or colleges have been consulted. RESULTS: In France, premature birth concerns 60,000 neonates every year (7.4 %), half of them are delivered after spontaneous onset of labor...
November 8, 2016: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
https://www.readbyqxmd.com/read/27813278/universal-cervical-length-screening-for-singleton-pregnancies-with-no-history-of-preterm-delivery-or-the-inverse-of-the-pareto-principle
#5
REVIEW
P Rozenberg
: Ultrasound measurement of cervical length in the general population enables the identification of women at risk for spontaneous preterm delivery. Vaginal progesterone is effective in reducing the risk of preterm delivery in this population. This screening associated with treatment by vaginal progesterone is cost-effective. Universal screening of cervical length can therefore be considered justified. Nonetheless, this screening will not appreciably reduce the preterm birth prevalence: in France or UK, where the preterm delivery rate is around 7...
November 4, 2016: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27812088/preterm-birth-prevention-post-conization-a-model-of-cervical-length-screening-with-targeted-cerclage
#6
Lindsay M Kindinger, Maria Kyrgiou, David A MacIntyre, Stefano Cacciatore, Angela Yulia, Joanna Cook, Vasso Terzidou, T G Teoh, Phillip R Bennett
Women with a history of excisional treatment (conization) for cervical intra-epithelial neoplasia (CIN) are at increased risk of preterm birth, perinatal morbidity and mortality in subsequent pregnancy. We aimed to develop a screening model to effectively differentiate pregnancies post-conization into low- and high-risk for preterm birth, and to evaluate the impact of suture material on the efficacy of ultrasound indicated cervical cerclage. We analysed longitudinal cervical length (CL) data from 725 pregnant women post-conization attending preterm surveillance clinics at three London university Hospitals over a ten year period (2004-2014)...
2016: PloS One
https://www.readbyqxmd.com/read/27777928/cervicovaginal-fluid-acetate-a-metabolite-marker-of-preterm-birth-in-symptomatic-pregnant-women
#7
Emmanuel Amabebe, Steven Reynolds, Victoria Stern, Graham Stafford, Martyn Paley, Dilly O C Anumba
Changes in vaginal microbiota that is associated with preterm birth (PTB) leave specific metabolite fingerprints that can be detected in the cervicovaginal fluid (CVF) using metabolomics techniques. In this study, we characterize and validate the CVF metabolite profile of pregnant women presenting with symptoms of threatened preterm labor (PTL) by both (1)H-nuclear magnetic resonance spectroscopy (NMR) and enzyme-based spectrophotometry. We also determine their predictive capacity for PTB, singly, and in combination, with current clinical screening tools - cervicovaginal fetal fibronectin (FFN) and ultrasound cervical length (CL)...
2016: Frontiers in Medicine
https://www.readbyqxmd.com/read/27665313/unplanned-30-day-hospital-readmission-as-a-quality-measure-in-gynecologic-oncology
#8
MaryAnn B Wilbur, Diana B Mannschreck, Ana M Angarita, Rayna K Matsuno, Edward J Tanner, Rebecca L Stone, Kimberly L Levinson, Sarah M Temkin, Martin A Makary, Curtis A Leung, Amy Deutschendorf, Peter J Pronovost, Amy Brown, Amanda N Fader
OBJECTIVES: Thirty-day readmission is used as a quality measure for patient care and Medicare-based hospital reimbursement. The primary study objective was to describe the 30-day readmission rate to an academic gynecologic oncology service. Secondary objectives were to identify risk factors and costs related to readmission. METHODS: This was a retrospective, concurrent cohort study of all surgical admissions to an academic, high volume gynecologic oncology service during a two-year period (2013-2014)...
December 2016: Gynecologic Oncology
https://www.readbyqxmd.com/read/27600735/universal-cervical-length-screening-for-preterm-birth-prevention-in-the-united-states
#9
Adeeb Khalifeh, Johanna Quist-Nelson, Vincenzo Berghella
OBJECTIVE: To evaluate the incidence of implementation of universal cervical length (CL) screening for preterm birth (PTB) prevention among institutions with Maternal-Fetal Medicine (MFM) fellowship training in the United states. METHODS: In January 2015, we conducted a national survey of institutions with MFM Fellowship Programs regarding implementation of universal CL screening, defined as CL screening of women with singleton gestations without a prior spontaneous PTB...
September 7, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27550735/racial-disparities-in-cervical-length-for-prediction-of-preterm-birth-in-a-low-risk-population
#10
Jessica N Buck, Kelly M Orzechowski, Vincenzo Berghella
PURPOSE: Racial minorities experience higher rates of spontaneous preterm birth (sPTB). Our objective was to evaluate whether there are racial discrepancies in the incidence of second trimester short cervical length (≤25mm). MATERIALS AND METHODS: Retrospective cohort of women with singleton gestations without prior sPTB undergoing universal second trimester transvaginal ultrasound cervical length (CL) screening between January 2012 and December 2013. Black women were compared to non-Hispanic white women...
August 23, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27542966/cost-effective-management-of-women-with-minor-cervical-lesions-revisiting-the-application-of-hpv-dna-testing
#11
Kine Pedersen, Emily A Burger, Stephen Sy, Ivar S Kristiansen, Jane J Kim
BACKGROUND: Lack of consensus in management guidelines for women with minor cervical lesions, coupled with novel screening approaches, such as human papillomavirus (HPV) genotyping, necessitate revisiting prevention policies. We evaluated the cost-effectiveness and resource trade-offs of alternative triage strategies to inform cervical cancer prevention in Norway. METHODS: We used a decision-analytic model to compare the lifetime health and economic consequences associated with ten novel candidate approaches to triage women with minor cervical lesions...
November 2016: Gynecologic Oncology
https://www.readbyqxmd.com/read/27476847/thirty-day-readmission-and-reoperation-after-surgery-for-spinal-tumors-a-national-surgical-quality-improvement-program-analysis
#12
Aditya V Karhade, Viren S Vasudeva, Hormuzdiyar H Dasenbrock, Yi Lu, William B Gormley, Michael W Groff, John H Chi, Timothy R Smith
OBJECTIVE The goal of this study was to use a large national registry to evaluate the 30-day cumulative incidence and predictors of adverse events, readmissions, and reoperations after surgery for primary and secondary spinal tumors. METHODS Data from adult patients who underwent surgery for spinal tumors (2011-2014) were extracted from the prospective National Surgical Quality Improvement Program (NSQIP) registry. Multivariable logistic regression was used to evaluate predictors of reoperation, readmission, and major complications (death, neurological, cardiopulmonary, venous thromboembolism [VTE], surgical site infection [SSI], and sepsis)...
August 2016: Neurosurgical Focus
https://www.readbyqxmd.com/read/27444208/vaginal-progesterone-decreases-preterm-birth%C3%A2-%C3%A2-%C3%A2-34%C3%A2-weeks-of-gestation-in-women-with-a-singleton-pregnancy-and-a-short-cervix-an-updated-meta-analysis-including-data-from-the-opptimum-study
#13
REVIEW
R Romero, K H Nicolaides, A Conde-Agudelo, J M O'Brien, E Cetingoz, E Da Fonseca, G W Creasy, S S Hassan
OBJECTIVE: To evaluate the efficacy of vaginal progesterone administration for preventing preterm birth and perinatal morbidity and mortality in asymptomatic women with a singleton gestation and a mid-trimester sonographic cervical length (CL) ≤ 25 mm. METHODS: This was an updated systematic review and meta-analysis of randomized controlled trials comparing the use of vaginal progesterone to placebo/no treatment in women with a singleton gestation and a mid-trimester sonographic CL ≤ 25 mm...
September 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27441291/screening-for-post-32-week-preterm-birth-risk-how-helpful-is-routine-perinatal-data-collection
#14
Wei Luo, Emily Y-S Huning, Truyen Tran, Dinh Phung, Svetha Venkatesh
BACKGROUND: Preterm birth is a clinical event significant but difficult to predict. Biomarkers such as fetal fibronectin and cervical length are effective, but the often are used only for women with clinically suspected preterm risk. It is unknown whether routinely collected data can be used in early pregnancy to stratify preterm birth risk by identifying asymptomatic women. This paper tries to determine the value of the Victorian Perinatal Data Collection (VPDC) dataset in predicting preterm birth and screening for invasive tests...
June 2016: Heliyon
https://www.readbyqxmd.com/read/27424445/-vasa-praevia-diagnosis-during-transvaginal-measurement-of-cervical-length-as-preventing-preterm-delivery-in-the-second-quarter
#15
L I Belmonte-Andújar, A M Fuentes-Rozalén, R M Soler-Garcia
BACKGROUND: Vasa praevia is a rare pregnancy complication with a high fetal mortality when not diagnosed in the prenatal period. CLINICAL CASES: two cases of vasa praevia diagnosed during the second trimester ultrasound cervical measurement. CONCLUSIONS: We propose carry out further investigation about cost effectiveness of double vaginal screening (cervical length measurement and vasa praevia) during the second trimester morphology ultrasound...
March 2016: Ginecología y Obstetricia de México
https://www.readbyqxmd.com/read/27411548/identification-of-a-novel-human-papillomavirus-by-metagenomic-analysis-of-vaginal-swab-samples-from-pregnant-women
#16
Zhijian Liu, Shixing Yang, Yan Wang, Quan Shen, Yan Yang, Xutao Deng, Wen Zhang, Eric Delwart
BACKGROUND: The number of members in the genus Gammapapillomavirus of Family Papillomaviridae has recently been expanding most rapidly. The aim of this study was to characterize a novel human gammapapillomavirus type identified in a vaginal swab from a 25-year-old pregnant woman suffering from vaginitis. METHODS: Viral metagenomics method was used to detect the viral sequences in 88 vaginal swab samples collected from 88 pregnant women with vaginitis. A novel papillomavirus, named HPV-ZJ01 (GenBank no...
2016: Virology Journal
https://www.readbyqxmd.com/read/27366309/molecular-detection-and-typing-of-human-papillomaviruses-in-paraffin-embedded-cervical-cancer-and-pre-cancer-tissue-specimens
#17
Pezhman Mahmoodi, Hossein Motamedi, Masoud Reza Seyfi Abad Shapouri, Mahjabin Bahrami Shehni, Mohammad Kargar
BACKGROUND: Cervical cancer is one of the important reasons of mortality among females. Prevention, early diagnosis and immediate treatment can affect the rate of mortality in this cancer and several epidemiological studies have shown a strong relationship between human papilloma viruses (HPVs) and cervical cancer. OBJECTIVES: The present study was conducted to survey HPV infections in a women population with cervical cancer and cervical dysplasia/metaplasia in southwest of Iran...
February 2016: Iranian Journal of Cancer Prevention
https://www.readbyqxmd.com/read/27280063/the-effect-of-a-universal-cervical-length-screening-program-on-antepartum-management-and-birth-outcomes
#18
Scott A Shainker, Anna M Modest, Michele R Hacker, Steven J Ralston
Objective The objective of this study was to evaluate the effect of a universal cervical length screening program on the incidence of antepartum interventions. Study Design This retrospective cohort study included women delivering ≥ 20 weeks of gestation with singleton pregnancies before and after implementing universal cervical length screening. Antepartum interventions included admission for threatened preterm birth, ≥ 2 cervical length measurements, cervical cerclage, neonatology consultation, betamethasone, antibiotic administration for preterm premature rupture of membranes, and tocolysis...
April 2016: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/27235918/biophysical-and-biochemical-screening-for-the-risk-of-preterm-labor-an-update
#19
REVIEW
Joseph R Wax, Angelina Cartin, Michael G Pinette
The heterogeneous causes of spontaneous preterm birth make prediction and prevention difficult. Recently developed biochemical and biophysical tests add significantly to clinicians' ability to evaluate and treat women at risk for spontaneous preterm birth. The primary importance of transvaginal cervical sonography and cervicovaginal fetal fibronectin lies in the high negative predictive values of the tests for preterm delivery risk. Cervical length may be useful in identifying women who are candidates for cervical cerclage or progesterone therapy for preterm birth prevention...
June 2016: Clinics in Laboratory Medicine
https://www.readbyqxmd.com/read/27176172/current-implementation-of-universal-cervical-length-screening-for-preterm-birth-prevention-in-the-united-states-19
#20
Adeeb Khalifeh, Johanna Quist-Nelson, Vincenzo Berghella
INTRODUCTION: To evaluate the incidence of implementation of universal cervical length (CL) screening for preterm birth (PTB) prevention among institutions with Maternal-Fetal Medicine (MFM) fellowship training in the United States. METHODS: In January 2015, we conducted a national survey of institutions with MFM Fellowship Programs regarding implementation of universal CL screening, defined as CL screening of women with singleton gestations without a prior spontaneous PTB...
May 2016: Obstetrics and Gynecology
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