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Vestibulopathy

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https://www.readbyqxmd.com/read/28443060/the-vestibular-implant-hearing-preservation-during-intralabyrinthine-electrode-insertion-a-case-report
#1
Raymond van de Berg, Florence Lucieer, Nils Guinand, Joost van Tongeren, Erwin George, Jean-Philippe Guyot, Herman Kingma, Marc van Hoof, Yasin Temel, Jacobus van Overbeeke, Angelica Perez-Fornos, Robert Stokroos
OBJECTIVE: The vestibular implant seems feasible as a clinically useful device in the near future. However, hearing preservation during intralabyrinthine implantation remains a challenge. It should be preserved to be able to treat patients with bilateral vestibulopathy and (partially) intact hearing. This case study investigated the feasibility of hearing preservation during the acute phase after electrode insertion in the semicircular canals. METHODS: A 40-year-old woman with normal hearing underwent a translabyrinthine approach for a vestibular schwannoma Koos Grade IV...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28404567/accidental-hydroxychloroquine-overdose-resulting-in-neurotoxic-vestibulopathy
#2
Peter B Chansky, Victoria P Werth
Hydroxychloroquine is an oral antimalarial medication commonly used off-label for a variety of rheumatological conditions, including systemic lupus erythematosus, rheumatoid arthritis, Sjögren's syndrome and dermatomyositis. We present a case of a 64-year-old woman who presented with acute onset headache, bilateral tinnitus, and left-sided facial numbness and tingling in the setting of accidentally overdosing on hydroxychloroquine. By the next morning, the patient began to experience worsening in the tingling sensation and it eventually spread to her left arm, thigh and distal extremities...
April 12, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28395427/-etiological-analysis-on-patients-in-department-of-vertigo-and-dizziness-oriented-outpatient
#3
F Li, X G Wang, J H Zhuang, Y Chen, X W Zhou, B Gao, H H Gu
Objective: We aimed to explore the spectrum of causes for patients in department of vertigo and dizziness oriented outpatient, in order to provide a reference for diagnosis and treatment of patients with vertigo or dizziness. Methods: Retrospective analysis were carried out with clinical data of patients in our department of vertigo and dizziness oriented outpatient. The target group under study was diagnosed based on the uniform diagnostic criteria, and re-visiting patients were excluded. Results: This clinical study was conducted on 5 348 cases, who visited our vertigo and dizziness oriented outpatient from December 2012 to July 2015...
April 11, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28391373/noisy-galvanic-vestibular-stimulation-an-emerging-treatment-option-for-bilateral-vestibulopathy
#4
Max Wuehr, Julian Decker, Roman Schniepp
Patients with bilateral vestibulopathy (BVP) suffer from persistent imbalance during standing and walking as well as an impaired gaze stabilization during head movements. Disabilities associated with BVP severely compromise patients' daily activities and are often linked to an increased risk of falls. Currently, the only established treatment option in BVP is physical therapy. However, treatment effects of physical therapy in BVP are most often limited and many patients do not adequately recover performance...
April 8, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28352247/refixation-saccades-with-normal-gain-values-a-diagnostic-problem-in-the-video-head-impulse-test-a-case-report
#5
Leise Elisabeth Hviid Korsager, Christian Emil Faber, Jesper Hvass Schmidt, Jens Højberg Wanscher
Refixation saccades with normal gain value occur more frequently with increasing age. The phenomenon has also been observed in different vestibular disorders. In this case, we present a young male with normal gain value and refixation saccades tested with the video head impulse test (vHIT) the day after his cochlear implantation. One month after surgery, refixation saccades were no longer present. This suggests that refixation saccades can occur as a result of temporary pathology such as surgery. Refixation saccades with normal gain values might reflect a partial deficit in the vestibulo-ocular reflex...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28346294/diagnosis-and-treatment-of-vestibular-neuritis-neuronitis-or-peripheral-vestibulopathy-pvp-open-questions-and-possible-answers
#6
Stefan C A Hegemann, Angela Wenzel
The acute vestibular syndrome is a clinically defined entity consisting of vertigo or dizziness that develops acutely over minutes to hours and is accompanied by nausea/vomiting, gait instability, head motion intolerance, and nystagmus, while persisting over a day or more. When it is caused by a peripheral vestibular lesion and is not associated with clinically manifest auditory deficits, it is mostly labeled vestibular neuritis/neuronitis/neuropathy or sometimes peripheral vestibulopathy. Here, we propose hypotheses and discuss current research advances on viral or vascular factors in the pathogenesis, the recurrence, the site of lesion, old and new treatment options, contraindicated measures, the differential diagnosis, and the prognosis of vestibular neuritis/neuronitis/neuropathy or vestibulopathy...
March 24, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28265260/role-of-the-patient-s-history-of-vestibular-symptoms-in-the-clinical-evaluation-of-the-bedside-head-impulse-test
#7
Christoph Helmchen, Julia Knauss, Peter Trillenberg, Anita Frendl, Andreas Sprenger
OBJECTIVE: Our aim was to identify the role of the investigators' knowledge of the patient's history of vestibular symptoms (PVH) in the clinical evaluation of the bedside head-impulse test (bHIT). We hypothesized that this knowledge will reduce uncertainty and improve bHIT accuracy when compared to quantitative analysis of the vestibulo-ocular reflex by video head-impulse test (vHIT). METHODS: We looked for changes in the clinical assessment of the bHIT in 594 consecutive patients before and after taking PVH...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28077250/role-of-video-head-impulse-test-in-lateralization-of-vestibulopathy-comparative-study-with-caloric-test
#8
Pona Park, Joo Hyun Park, Ji Soo Kim, Ja-Won Koo
OBJECTIVE: To evaluate the lateralization value of video head-impulse test (vHIT) for the diagnosis of vestibulopathy and to analyze cases showing dissociated results with caloric test. METHODS: In total, 19 healthy volunteers and 92 dizzy patients who underwent both a caloric test and a vHIT were enrolled. Patients were divided into two groups depending on their fluctuating pattern of vertigo. The vestibulo-ocular reflex (VOR) gain and gain asymmetry (GA) of a vHIT as well as unilateral weakness (UW) and the sum of the slow-phase velocities (SPVs) of warm and cold irrigation of the same side were compared...
January 8, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/27941523/3-d-spatial-memory-and-navigation-functions-and-disorders
#9
Thomas Brandt, Andreas Zwergal, Stefan Glasauer
PURPOSE OF REVIEW: The aim of this review is to report on the specialized neuronal systems mediating spatial orientation and navigation discovered in animal experiments. These findings have important implications for the clinical management of patients with vestibular disorders or dementia and for translational research in these fields. RECENT FINDINGS: The following anatomically and functionally separate, but nevertheless cooperative cell types have been characterized: angular head velocity cells and head direction cells, which depend on vestibular input and interact with place cells and grid cells, which represent position and distance...
February 2017: Current Opinion in Neurology
https://www.readbyqxmd.com/read/27878442/clinical-and-neurophysiological-risk-factors-for-falls-in-patients-with-bilateral-vestibulopathy
#10
Roman Schniepp, Cornelia Schlick, Fabian Schenkel, Cauchy Pradhan, Klaus Jahn, Thomas Brandt, Max Wuehr
Patients with bilateral vestibular failure (BVF) exhibit imbalance when standing and walking that is linked to a higher fall risk. The purpose of this study was to identify risk factors for falls in BVF. We therefore systematically investigated the interrelationship of clinical and demographic characteristics, gait impairments, and the fall frequency of these patients. Clinical and demographic characteristics as well as quantitative measures of gait performance on a pressure-sensitive gait carpet were collected from 55 patients with different etiologies of BVF...
November 22, 2016: Journal of Neurology
https://www.readbyqxmd.com/read/27871453/chasing-dizzy-chimera-diagnosis-of-combined-peripheral-and-central-vestibulopathy
#11
Seo-Young Choi, Hyo-Jung Kim, Ji-Soo Kim
Diagnosis of combined peripheral and central vestibulopathy remains a challenge since the findings from peripheral vestibular involvements may overshadow those from central vestibular disorders or vice versa. The aim of this study was to enhance detection of these intriguing disorders by characterizing the clinical features and underlying etiologies. We had recruited 55 patients with combined peripheral and central vestibulopathy at the Dizziness Clinic of Seoul National University Bundang Hospital from 2003 to 2013...
December 15, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/27869225/noisy-galvanic-vestibular-stimulation-induces-a-sustained-improvement-in-body-balance-in-elderly-adults
#12
Chisato Fujimoto, Yoshiharu Yamamoto, Teru Kamogashira, Makoto Kinoshita, Naoya Egami, Yukari Uemura, Fumiharu Togo, Tatsuya Yamasoba, Shinichi Iwasaki
Vestibular dysfunction causes postural instability, which is prevalent in the elderly. We previously showed that an imperceptible level of noisy galvanic vestibular stimulation (nGVS) can improve postural stability in patients with bilateral vestibulopathy during the stimulus, presumably by enhancing vestibular information processing. In this study, we investigated the after-effects of an imperceptible long-duration nGVS on body balance in elderly adults. Thirty elderly participants underwent two nGVS sessions in a randomised order...
November 21, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27845944/the-vestibular-system-and-cognition
#13
Paul F Smith
PURPOSE OF REVIEW: The last year has seen a great deal of new information published relating vestibular dysfunction to cognitive impairment in humans, especially in the elderly. The objective of this review is to summarize and critically evaluate this new evidence in the context of the previous literature. RECENT FINDINGS: This review will address the recent epidemiological/survey studies that link vestibular dysfunction with cognitive impairment in the elderly; recent clinical investigations into cognitive impairment in the context of vestibular dysfunction, both in the elderly and in the cases of otic capsule dehiscence and partial bilateral vestibulopathy; recent evidence that vestibular impairment is associated with hippocampal atrophy; and finally recent evidence relating to the hypothesis that vestibular dysfunction could be a risk factor for dementia...
February 2017: Current Opinion in Neurology
https://www.readbyqxmd.com/read/27814315/compensatory-saccades-in-head-impulse-testing-influence-the-dynamic-visual-acuity-of-patients-with-unilateral-peripheral-vestibulopathy1
#14
V G Wettstein, K P Weber, C J Bockisch, S C Hegemann
BACKGROUND: Both the dynamic visual acuity (DVA) test and the video head-impulse test (vHIT) are fast and simple ways to assess peripheral vestibulopathy. After losing peripheral vestibular function, some patients show better DVA performance than others, suggesting good compensatory mechanisms. It seems possible that compensatory covert saccades could be responsible for improved DVA. OBJECTIVE: To investigate VOR gain and compensatory saccades with vHIT and compare them to the DVA of patients with unilateral peripheral vestibulopathy...
November 3, 2016: Journal of Vestibular Research: Equilibrium & Orientation
https://www.readbyqxmd.com/read/27766472/delayed-vestibulopathy-after-heat-exposure
#15
Ileok Jung, Seo-Young Choi, Hyo-Jung Kim, Ji-Soo Kim
Even though dizziness is a common symptom of heat illness, comprehensive evaluation of the vestibular function has not been available in this potentially life-threatening disorder. Three patients developed vertigo about a week after heat exposure. Evaluation showed bilateral impairments of the vestibulo-ocular reflex during head impulses and the signs of vestibulocerebellar dysfunction that included spontaneous downbeat nystagmus, gaze-evoked nystagmus, and positional downbeat nystagmus. Exposure to excessive heat may give rise to delayed vestibulopathy by damaging the vestibulocerebellum...
January 2017: Journal of Neurology
https://www.readbyqxmd.com/read/27747687/prolonged-neuropsychiatric-symptoms-in-a-military-service-member-exposed-to-mefloquine
#16
Jeffrey Livezey, Thomas Oliver, Louis Cantilena
A 32-year-old male developed neuropsychiatric symptoms 2 weeks after starting mefloquine 250 mg/week for malaria prophylaxis. He continued to take the medication for the next 4 months. Initial symptoms included vivid dreams and anxiety, as well as balance problems. These symptoms persisted and progressed over the next 4 years to include vertigo, emotional lability, and poor short-term memory, which have greatly affected his personal and professional life. An extensive evaluation revealed objective evidence supporting a central vestibulopathy...
December 2016: Drug Safety—Case Reports
https://www.readbyqxmd.com/read/27735223/associations-between-bipedal-stance-stability-and-locomotor-stability-following-a-trip-in-unilateral-vestibulopathy
#17
Christopher McCrum, Katrin Eysel-Gosepath, Gaspar Epro, Kenneth Meijer, Hans H C M Savelberg, Gert-Peter Brüggemann, Kiros Karamanidis
Posturography is used to assess balance in clinical settings, but its relationship to gait stability is unclear. We assessed if dynamic gait stability is associated with standing balance in 12 patients with unilateral vestibulopathy. Participants were unexpectedly tripped during treadmill walking and the change in the margin of stability (MoSchange) and base of support (BoSchange) relative to non-perturbed walking was calculated for the perturbed and first recovery steps. The centre of pressure (COP) path during 30s stance with eyes open and closed, and the distance between the most anterior point of the COP and the anterior BoS boundary during forward leaning (ADist) were assessed using a force plate...
October 13, 2016: Journal of Applied Biomechanics
https://www.readbyqxmd.com/read/27673096/poster-343-posterior-circulation-stroke-with-secondary-vestibulopathy-a-case-report
#18
Jared R Levin, Olivera D Pekovic
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27638075/bilateral-vestibulopathy
#19
REVIEW
M Strupp, K Feil, M Dieterich, T Brandt
The leading symptoms of bilateral vestibulopathy (BVP) are postural imbalance and unsteadiness of gait that worsens in darkness and on uneven ground. There are typically no symptoms while sitting or lying under static conditions. A minority of patients also have movement-induced oscillopsia, in particular while walking. The diagnosis of BVP is based on a bilaterally reduced or absent function of the vestibulo-ocular reflex (VOR). This deficit is diagnosed for the high-frequency range of the angular VOR by a bilaterally pathologic bedside head impulse test (HIT) and for the low-frequency range by a bilaterally reduced or absent caloric response...
2016: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/27624122/altered-processing-of-otolithic-information-in-isolated-lateral-medullary-infarction
#20
Hyo-Jung Kim, Seoyeon Kim, Jae Han Park, Ji-Soo Kim
Ocular and cervical vestibular-evoked myogenic potentials (VEMPs) evaluate the function of otolithic pathways in central as well as peripheral vestibular disorders. This study aimed to determine the associations and dissociations of otolithic dysfunction in lateral medullary infarction (LMI), the most well-known disorder of central vestibulopathy. At the Dizziness Clinic of a referral-based University Hospital, 45 patients with isolated LMI (28 men, mean age = 55.6 ± 12.5) had evaluation of the ocular tilt reaction (OTR), tilt of the subjective visual vertical (SVV), and ocular and cervical VEMPs from Janurary 2011 to August 2015 during the acute phase, 1-11 days from the symptom onset (median = 2 days)...
December 2016: Journal of Neurology
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