Erik Martin, Sofie de Hoon, Joost Stultiens, Miranda Janssen, Hans Essers, Kenneth Meijer, Wouter Bijnens, Maurice van de Berg, Nolan Herssens, Sebastien Janssens de Varebeke, Ann Hallemans, Vincent Van Rompaey, Nils Guinand, Angelica Perez-Fornos, Josine Widdershoven, Raymond van de Berg
BACKGROUND: DFNA9 is a genetic disease of the inner ear, causing progressive bilateral sensorineural deafness and bilateral vestibulopathy (BV). In this study, DizzyQuest, a mobile vestibular diary, and the MOX accelerometer were combined to assess the daily life functional limitations and physical activity of patients with DFNA9 suffering from BV. These parameters might be appropriate as potential candidacy criteria and outcome measures for new therapeutic interventions for BV. METHODS: Fifteen DFNA9 patients with BV and twelve age-matched healthy controls were included...
February 17, 2024: Journal of Clinical Medicine