keyword
https://read.qxmd.com/read/38078310/gastric-glomus-tumors-the-roles-of-endoscopic-ultrasound-and-shared-decision-making
#21
Alexander Malik, Muhammad Nadeem Yousaf, Sami Samiullah, Veysel Tahan
Gastric glomus tumors (GGTs) are mesenchymal neoplasms with indolent behavior that originate from the subepithelial layers of the stomach and represent up to 1% of all gastric tumors. GGT is detected incidentally during esophagogastroduodenoscopy (EGD) in a proportion of patients. Endoscopic ultrasound (EUS) evaluation of GGT is essential to establish the diagnosis and to differentiate it from gastrointestinal stromal tumors or gastric neuroendocrine tumors. An 80-year-old man who presented for abdominal discomfort was incidentally found to have a gastric antral nodule on EGD...
2023: Case Reports in Gastroenterology
https://read.qxmd.com/read/38074478/sinonasal-neuroendocrine-carcinoma-in-adult-proteus-syndrome
#22
Giorgos Sideris, Thomas Nikolopoulos, Antigone Sourla, Penelope Korkolopoulou, Pavlos Papadakis, Alexander Delides
INTRODUCTION: Proteus syndrome (PS) is a rare genetic disorder usually caused by mutations in AKT1 or PTEN genes, characterized by multiple, asymmetric tissue overgrowth with high clinical variability. Sinonasal neuroendocrine carcinomas (SNEC) are exceptionally rare tumors encountered in the ethmoid sinus, nasal cavity, or maxillary sinus. CASE REPORT: We report a 35-year-old patient with PS, who underwent successful surgical removal of a well-differentiated SNEC obstructing his nasal cavity and highlight the role of the otolaryngologist for safe airway management, minimal surgical intervention and coordination of the multidisciplinary care...
November 2023: Iranian Journal of Otorhinolaryngology
https://read.qxmd.com/read/38008873/a-successful-central-gastrectomy-and-gastro-gastric-anastomosis-for-a-large-gastric-gist
#23
JOURNAL ARTICLE
Mohamed Zidan, Eslam Hassan, Mostafa Refaie
PURPOSE: Partial gastrectomy is always the preferred technique for GIST resection. Central gastrectomy is a practical technique that can be employed in many situations during the resection of both subepithelial stromal tumors and gastric tumors. CASE PRESENTATION: A 53-year-old Egyptian female patient with a 15 × 19 cm large fungating gastric GIST managed by central gastrectomy. Central gastrectomy and gastro-gastric anastomosis were performed with negative resection margins, and the patient received post-operative imatinib, achieving disease control throughout an 8-month post-operative follow-up...
November 27, 2023: Journal of Gastrointestinal Cancer
https://read.qxmd.com/read/37977671/band-and-sink-for-gi-subepithelial-tumors-provided-it-is-not-a-kitchen-sink-approach
#24
EDITORIAL
Amol Bapaye, Rohan Yewale
No abstract text is available yet for this article.
December 2023: Gastrointestinal Endoscopy
https://read.qxmd.com/read/37928970/an-asymptomatic-patient-with-colonic-leiomyoma
#25
Saad Alkhowaiter, Abdulmalik Alsheikh, Ammar Alotaibi
Subepithelial lesions (SELs) originating from muscularis mucosae of the colon are very rare findings on endoscopy. Appropriate management of SELs involves making a correct diagnosis and estimating their malignant potential. In this case study, a 58-year-old Saudi man presented with a small, 8-mm sigmoid polyp during screening colonoscopy. The polyp was removed by hot snare polypectomy and sent to pathology laboratory. Report showed an unremarkable colonic mucosa and underlying well-circumscribed submucosal lesion composed of monotonous spindle cells...
2023: Case Reports in Gastroenterology
https://read.qxmd.com/read/37900853/laparoscopically-resected-ectopic-hepatocellular-carcinoma-mimicking-subepithelial-tumor-of-stomach-a-case-report
#26
Yong-Eun Park
Ectopic hepatocellular carcinoma (HCC) can be defined as an HCC arising from hepatic parenchyma located in an extrahepatic organ or tissue. Fewer than 100 cases of ectopic liver have been reported. In 30 of these cases, HCC was detected in ectopic tissue. The author describes a case of ectopic HCC mimicking subepithelial tumor (SET) of the stomach successfully treated by laparoscopic resection. This case report also provides a pertinent review of the literature. A 61-year-old male was referred to our department for the management of an intra-abdominal mass found on abdominal computed tomography performed at a local medical center due to a 2-month history of vague abdominal pain...
2023: Case Reports in Oncology
https://read.qxmd.com/read/37883220/giant-fibrovascular-polyp-mimicking-esophageal-malignancy-on-18-f-fdg-pet-ct
#27
JOURNAL ARTICLE
MinJeong Kim, Kum Ju Chae, Jong-Hun Kim, Yeon-Hee Han
A 52-year-old man presented with continuous dull pain from the throat to the epigastric region with dysphagia. Initial endoscopy misdiagnosed a subepithelial tumor causing external compression of the esophagus. A CT scan visualized a 14.0 × 4.0-cm pedunculated mass inside the esophagus. Subsequent 18 F-FDG PET/CT identified an intense FDG-avid area in the mass, which strongly suggested esophageal cancer. Total mass excision was performed, and fibrovascular polyp with chronic ulcerative inflammation was finally confirmed on histologic examination...
December 1, 2023: Clinical Nuclear Medicine
https://read.qxmd.com/read/37882208/diffuse-large-b-cell-lymphoma-and-gastrointestinal-kaposi-s-sarcoma-a-rare-cause-of-upper-gastrointestinal-bleeding
#28
JOURNAL ARTICLE
Carmen Amor Costa, Joaquín Fisac Vázquez, María Dolores Martín-Arranz
A 49-year-old man with a history of human immunodeficiency virus (HIV) infection, in a state of advanced immunosuppression and current antiretroviral therapy initiation. He was admitted to the hematology department after diagnosis of diffuse large B-cell lymphoma (DLBCL) associated with Epstein-Barr virus (EBV), disseminated cytomegalovirus (CMV) infection and cutaneous Kaposi's sarcoma (KS). During admission, he presented an episode of melena with anemization, so an urgent gastroscopy was performed. In the stomach there were multiple erythematous lesions, large and elevated, suggestive of subepithelial origin...
October 26, 2023: Revista Española de Enfermedades Digestivas
https://read.qxmd.com/read/37860780/gastric-schwannoma-two-case-reports-and-review-of-the-literature
#29
Rodrigo Cordeiro, Margarida Morgado, Vera Oliveira, Miguel Bispo, Mireia Castillo-Martin, Celso Matos
Gastric schwannomas are rare, slow-growing tumors whose clinical presentation is nonspecific. These are mostly benign, with a low probability of malignant transformation and an excellent prognosis. We present 2 cases of gastric schwannomas with distinct clinical features and imaging patterns, whose therapeutic approach differed. Case 1 is a 73-year-old woman with a voluminous subepithelial lesion in the greater gastric curvature, with predominantly endoluminal growth. Clinically the patient presented with nonspecific abdominal complaints and underwent complete surgical excision...
December 2023: Radiology Case Reports
https://read.qxmd.com/read/37852331/endoscopic-resection-of-giant-esophageal-subepithelial-lesions-experience-from-a-large-tertiary-center
#30
JOURNAL ARTICLE
An-Yi Xiang, Ke-Hao Wang, Wei Su, Tao Tan, Yi-Fan Qu, Xiao-Qing Li, Yun Wang, Ming-Yan Cai, Quan-Lin Li, Yi-Qun Zhang, Hao Hu, Ping-Hong Zhou
BACKGROUND AND AIMS: Increased reports on endoscopic resection (ER) of esophageal giant subepithelial lesions (g-SELs) have emerged in recent years. We aimed to evaluate the efficacy, technical difficulty and safety through our single-center experience. METHODS: 75 patients with g-SELs undergoing ER were included in the training set. Clinicopathological features, procedure-related characteristics, postprocedural outcomes and follow-up data were analyzed. A predictive nomogram model for procedural difficulty was proposed on the basis of the multivariable logistic regression analysis...
October 16, 2023: Gastrointestinal Endoscopy
https://read.qxmd.com/read/37817675/camrelizumab-induced-oral-lichenoid-reaction-with-subepithelial-cd4-t-cell-infiltration
#31
JOURNAL ARTICLE
Xiangjian Wang, Tao Fu, Weilian Sun
INTRODUCTION: Camrelizumab is a novel anti-programed cell death-1 (PD-1) antibody that has been investigated for the treatment of various malignancies. Increasing immune-related adverse events have been reported in clinical practice, with CD4+ T-cell-mediated-reactive cutaneous capillary endothelial proliferation being the most common. Camrelizumab-induced oral lichenoid reaction (OLR) appears to be a rare adverse effect compared with other anti-PD therapies induced OLR, with the main pathogenesis of activated CD8+ T cells mediating autoimmune reactions...
October 11, 2023: Journal of Oncology Pharmacy Practice
https://read.qxmd.com/read/37808075/surgical-management-of-gastrointestinal-stromal-tumors
#32
JOURNAL ARTICLE
Heather Townsend
Gastrointestinal stromal tumors (GISTs) are considered rare, but they are one of the most common malignant mesenchymal tumors within the gastrointestinal tract, affecting 4,000 to 6,000 adults in the United States each year. Because gastrointestinal bleeding is often the initial symptom, a thorough and timely diagnostic workup is imperative to accurately diagnose a potentially deadly tumor. Endoscopic ultrasound is helpful when working through a differential diagnosis of subepithelial lesions and can help identify which mucosal layer the lesion originates from, as well as the density of the lesion; however, surgical resection is the standard of care for the treatment of a resectable nonmetastatic GIST...
September 2023: Journal of the Advanced Practitioner in Oncology
https://read.qxmd.com/read/37790036/gastric-schwannoma-a-rare-subepithelial-lesion-of-the-stomach
#33
Sameeta Kumari, Muhammad Ibrahim Saeed, Adeel Urrehman
Gastric schwannomas (GS) are rare, slow-growing, benign subepithelial (SE) lesions of the stomach. These are difficult to differentiate preoperatively from other types of SE lesions, as the gross appearance and clinical presentation are very similar especially the gastrointestinal stromal tumors (GISTs), which are the most common SE lesions of the stomach. We present the case of a 35-year-old Asian man with a one-month history of intermittent, right, upper quadrant pain and hematemesis. Preoperatively, intravenous contrast-enhanced computer tomography scan (CECT) showed a well-circumscribed lesion in the upper abdomen closer to the stomach's lesser curvature...
September 2023: Curēus
https://read.qxmd.com/read/37743812/case-of-esophageal-actinomycosis-occurred-after-endoscopic-mucosal-resection-for-subepithelial-tumor
#34
Hang T T Nguyen, Jin Woong Cho, Sang Gyeun Kim, Tuyen Thanh Hoang, Gum Mo Jung, Bong Ju Cho, Myoung Jin Ju
Esophageal actinomycosis is a rare, chronic granulomatous disease caused by Actinomyces species. Endoscopy and biopsy are essential for making a diagnosis. This paper reports a case of esophageal actinomycosis that developed after an endoscopic mucosal resection (EMR) for a subepithelial tumor (SET). A 74-year-old male patient had a 3 cm flat, smooth elevation in the esophagus without symptoms. The SET was partially resected, and histology revealed "nonspecific degenerated mesenchymal tissue". Three months later, the patient exhibited a persistently large ulceration at the EMR site, and a biopsy revealed actinomycosis...
September 25, 2023: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://read.qxmd.com/read/37732355/-grey-areas-in-large-rectal-neuroendocrine-tumors-when-endoscopic-ultrasound-becomes-the-silver-lining
#35
JOURNAL ARTICLE
Vi Tor Macedo Silva, Joana Magalhães, Sílvia Leite, José Cotter
A 50-years old male with irrelevant medical history underwent colonoscopy for colorectal cancer screening. On the distal rectum, a subpedunculated (Paris classification Isp) lesion with 15mm was detected. This lesion presented yellowish mucosa and had irregular surfaces, suggesting a subepithelial lesion. Bite-on-bite biopsy confirmed a well-differentiated neuroendocrine tumor (r-NET), positive for synaptophysin, with a low-proliferative index. As r-NETs with 10-20mm fall on a grey area between endoscopic or surgical treatment, a lower endoscopic ultrasound (EUS) was performed, showing a round hypoechoic "salt and pepper" lesion of the mucosa, with focal involvement of the submucosa (3rd layer), but without muscularis propria invasion or regional lymph node involvement (uT1N0)...
September 21, 2023: Revista Española de Enfermedades Digestivas
https://read.qxmd.com/read/37731837/a-case-of-asymptomatic-gastric-plexiform-fibromyxoma-followed-up-for-3-years
#36
Naomi Sugimura, Eiji Kubota, Makiko Sasaki, Shigeki Fukusada, Yusuke Mizuno, Hiroyasu Iwasaki, Mamoru Tanaka, Keiji Ozeki, Takaya Shimura, Hiromi Kataoka
Plexiform fibromyxoma is a rare mesenchymal tumor identified in recent years and presents as a gastrointestinal submucosal tumor that is typically located in the gastric antrum. We report a case of gastric plexiform fibromyxoma in which the diagnosis was difficult despite repeated tissue sampling. Before visiting our hospital, the patient had been followed up for 3 years without a definitive diagnosis despite serial examinations, including computed tomography, endoscopy, endoscopic ultrasound, and endoscopic ultrasound-guided fine-needle aspiration...
April 2024: DEN Open
https://read.qxmd.com/read/37701681/goldilocks-principle-of-minimally-invasive-surgery-for-gastric-subepithelial-tumors
#37
JOURNAL ARTICLE
Wei-Jung Chang, Lien-Cheng Tsao, Hsu-Heng Yen, Chia-Wei Yang, Hung-Chi Chang, Chew-Teng Kor, Szu-Chia Wu, Kuo-Hua Lin
BACKGROUND: Minimally invasive surgery had been tailored to individual cases of gastric subepithelial tumors (SETs) after comparing the clinical outcomes of endoscopic resection (ER), laparoscopic resection (LR), and hybrid methods. AIM: To study the use of Goldilocks principle to determine the best form of minimally invasive surgery for gastric SETs. METHODS: In this retrospective study, 194 patients of gastric SETs with high probability of surgical intervention were included...
August 27, 2023: World Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/37681269/endoscopic-ultrasonography-guided-fine-needle-aspiration-for-duodenal-subepithelial-lesions-showing-a-hypoechoic-mass-on-endoscopic-ultrasound-imaging
#38
JOURNAL ARTICLE
Kazuaki Akahoshi, Kazuya Akahoshi, Yuki Shiratsuchi, Shinichi Tamura, Kento Uemura, Reiichi Sashihara, Yoshihiro Ohishi, Kanako Inoue, Tadashi Koga, Hidenobu Koga
BACKGROUND/AIMS: For duodenal subepithelial lesions showing a hypoechoic mass on endoscopic ultrasound imaging, the utility of endoscopic ultrasound-guided fine-needle aspiration and the frequency of histological types have not been the focus of previous literature. This study aimed to clarify this. MATERIALS AND METHODS: This prospective observational study enrolled 22 consecutive patients who underwent endoscopic ultrasoundguided fine-needle aspiration for duodenal subepithelial lesions with hypoechoic mass on endoscopic ultrasound...
September 8, 2023: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://read.qxmd.com/read/37663888/vaginal-metastasis-of-lung-cancer-a-case-report
#39
Federica Savasta, Michele Giana, Alessandro Libretti, Silvia Genestroni, Daniela Surico, Valentino Remorgida
Lung adenosquamous carcinoma (ASC) is a rare biphasic malignant tumor with squamous cell carcinoma (SCC) and adenocarcinoma (AC) components. ASC is reported to be aggressive; the most common metastatic sites are the regional lymph nodes and surrounding areas. A 46-year-old woman was referred to the emergency department with a persistent dry cough. She underwent fibro-bronchoscopy and was diagnosed with an adenosquamous lung carcinoma. Other than pulmonary and lymphatic findings, a total-body computed tomography (CT) examination highlighted a hypodense formation, of about 9 mm, with a cystic appearance, at the level of the vaginal region...
September 2023: Case Reports in Women's Health
https://read.qxmd.com/read/37663113/endoscopic-ultrasound-artificial-intelligence-assisted-for-prediction-of-gastrointestinal-stromal-tumors-diagnosis-a-systematic-review-and-meta-analysis
#40
JOURNAL ARTICLE
Rômulo Sérgio Araújo Gomes, Guilherme Henrique Peixoto de Oliveira, Diogo Turiani Hourneaux de Moura, Ana Paula Samy Tanaka Kotinda, Carolina Ogawa Matsubayashi, Bruno Salomão Hirsch, Matheus de Oliveira Veras, João Guilherme Ribeiro Jordão Sasso, Roberto Paolo Trasolini, Wanderley Marques Bernardo, Eduardo Guimarães Hourneaux de Moura
BACKGROUND: Subepithelial lesions (SELs) are gastrointestinal tumors with heterogeneous malignant potential. Endoscopic ultrasonography (EUS) is the leading method for evaluation, but without histopathological analysis, precise differentiation of SEL risk is limited. Artificial intelligence (AI) is a promising aid for the diagnosis of gastrointestinal lesions in the absence of histopathology. AIM: To determine the diagnostic accuracy of AI-assisted EUS in diagnosing SELs, especially lesions originating from the muscularis propria layer...
August 16, 2023: World Journal of Gastrointestinal Endoscopy
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