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Subepithelial tumor

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https://www.readbyqxmd.com/read/29282573/endoscopic-full-thickness-resection-of-gastric-and-duodenal-subepithelial-lesions-using-a-new-flat-based-over-the-scope-clip
#1
Wouter F W Kappelle, Yara Backes, Gerlof D Valk, Leon M G Moons, Frank P Vleggaar
BACKGROUND: Surgical resection of upper gastrointestinal (GI) subepithelial tumors (SETs) is associated with significant morbidity and mortality. A new over-the-scope (OTS) clip can be used for endoscopic full-thickness resection (eFTR). We aimed to prospectively evaluate feasibility and safety of upper GI eFTR with a new, flat-based OTS clip. METHODS: Consecutive patients with a gastric or duodenal SET < 20 mm were prospectively included. After identification of the lesion, the clip was placed and lesions were resected...
December 27, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29250649/inflammatory-juvenile-compound-conjunctival-nevi-a-clinicopathological-study-and-literature-review
#2
Claudia Florida Costea, Mihaela Dana Turliuc, Gabriela Dimitriu, Camelia Margareta Bogdănici, Anca MoŢoc, Mădălina Adriana Chihaia, Cristina Dancă, Andrei Cucu, Alexandru Cărăuleanu, Nicoleta Dumitrescu, Lucia Indrei, Şerban Turliuc
AIM: The conjunctival nevus affecting children and adolescents is a rare condition and the literature showed only few reports on this issue. The aim of this article is to determine the histopathological features for the correct diagnosis of an inflammatory juvenile compound nevus of the conjunctiva (IJCNC) in order to make the difference between this tumor and other lesions, like conjunctival melanoma or lymphoma, very similar from a gross point of view. This article is a clinical pathological study of two cases of IJCNC with particular histopathological characteristics, who were admitted at the 2nd Ophthalmology Clinic, "Prof...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/29245294/gastrointestinal-stromal-tumor-of-unusual-phenotype-after-imatinib-treatment-a-case-report-and-diagnostic-utility-of-etv1-mrna-in-situ-hybridization
#3
Minsun Jung, Sung-Hye Park, Yoon Kyung Jeon, Jae-Kyung Won, Han-Kwang Yang, Woo Ho Kim
RATIONALE: Gastrointestinal stromal tumor (GIST) is the most common tumor of mesenchymal origin in gastrointestinal tract. Immunohistochemical (IHC) staining combined with a typical morphology is used for the diagnosis of GIST. Typically, IHC staining for v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene (KIT) and discovered on GIST-1(DOG1) is positive in almost all GISTs. However, imatinib mesylate, a specific inhibitor of KIT tyrosine kinase, frequently involves changes in the morphology and IHC staining of GIST, impeding the diagnosis...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29245254/a-primary-gastric-synovial-sarcoma-a-case-report-and-literature-review
#4
REVIEW
In Tae So, Kwang Bum Cho, Ju Yup Lee, Sang Jin Kim, Hye In Jung, Jong Hwan Choi, Yoo Jin Lee, Hyun Jik Lee, Kyung Sik Park, Seung Wan Ryu, Yu Na Kang
RATIONALE: When a gastric spindle cell tumor is observed, the possibility of synovial carcinoma, besides common mesenchymal tumor, should also be considered. PRESENTING CONCERNS OF THE PATIENT: The patient is a 51-year-old American woman who underwent medical check-up at a general hospital. Upper endoscopy showed a 2-cm sized mass covered with intact mucosa, and a central depression located on the posterior wall of the mid body. Biopsy of the mass showed focal atypical cells proliferation in mucosa on hematoxylin & eosin (H&E) staining...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29243411/randomized-crossover-trial-comparing-eus-guided-fine-needle-aspiration-with-eus-guided-fine-needle-biopsy-for-gastric-subepithelial-tumors
#5
Tomohisa Iwai, Mitsuhiro Kida, Hiroshi Imaizumi, Shiro Miyazawa, Kosuke Okuwaki, Hiroshi Yamauchi, Toru Kaneko, Rikiya Hasegawa, Eiji Miyata, Wasaburo Koizumi
AIM: The purpose of this study is to compare the diagnostic yield of endoscopic ultrasound (EUS)-guided fine-needle aspiration (EUS-FNA) and EUS-guided fine-needle biopsy (EUS-FNB) for gastric subepithelial tumors (SET). METHODS: Patients diagnosed SET derived from fourth layer of the stomach were prospectively enrolled and randomly assigned to undergo both EUS-FNA using standard needle and EUS-FNB using a core biopsy needle alternatively to the same lesion a total of four times per session...
December 15, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29204254/gastric-metastasis-from-ovarian-adenocarcinoma-presenting-as-a-subepithelial-tumor-and-diagnosed-by-endoscopic-ultrasound-guided-tissue-acquisition
#6
Filippo Antonini, Liboria Laterza, Lorenzo Fuccio, Massimo Marcellini, Lucia Angelelli, Sonia Calcina, Corrado Rubini, Giampiero Macarri
We describe an uncommon case of a patient with a metastatic adenocarcinoma of ovarian origin presented as a gastric subepithelial tumor (SET) and that was diagnosed by endoscopic ultrasound fine-needle biopsy (EUS-FNB). Malignant gastric lesions are rarely metastatic and the primary tumor is mainly breast, lung, esophageal cancer or cutaneous melanoma. Gastric metastasis from ovarian cancer is unusual, presenting synchronously with the primary tumor but also several years later than the initial diagnosis. From an endoscopic point of view, gastric metastasis does not present specific features...
November 15, 2017: World Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/29196941/gastric-calcifying-fibrous-tumor-manifesting-as-a-subepithelial-tumor
#7
Seokyoun Lee, Jaehoon Jahng, Weoncheol Han
A gastric subepithelial tumor is a common finding during upper gastric endoscopy. The differential diagnosis of such lesions is broad, and sometimes a rare disease can be diagnosed. A calcifying fibrous tumor (CFT) is a rare, benign mesenchymal tumor that usually affects children and young adults. To our knowledge, a CFT of the tubular gastrointestinal tract is very rare with fewer than 30 cases of gastric CFTs reported in the literature.
December 1, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29102730/unusual-gastric-subepithelial-tumor-primary-mixed-acinar-endocrine-neoplasm-in-an-anemic-woman
#8
Imran Uraizee, John Hart, Irving Waxman, Christopher R Weber, Namrata Setia
No abstract text is available yet for this article.
November 2, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29077606/endoscopic-full-thickness-resection-for-gastric-subepithelial-tumors-originating-from-the-muscularis-propria-a-69-case-series
#9
Meiling Sun, Jitao Song, Xinuan Song, Bingrong Liu
OBJECTIVE: This report describes a mini-invasive technique called endoscopic full-thickness resection (EFR) for the treatment of gastric subepithelial tumors (SETs) originating from the muscularis propria (MP). MATERIALS AND METHODS: We retrospectively analyzed 69 patients with gastric SETs originating from the MP at our hospital between September 2009 and July 2016. The data from each patient were reviewed, including patient information, tumor characteristics, procedure-related data, and recurrence rates...
October 26, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/29030800/endoscopic-treatment-of-subepithelial-lesions-of-the-gastrointestinal-tract
#10
REVIEW
Vivien Wai Yin Wong, Osamu Goto, Hans Gregersen, Philip Wai Yan Chiu
Purpose of Review The study aimed to discuss novel endoscopic approaches to resection of submucosal lesions. Recent Findings Endoscopic resection by excavation, full-thickness resection, and submucosal tunneling are by now well-documented techniques for submucosal tumor resection. Combined approaches with laparoscopy such as several variations of laparoscopic endoscopic cooperation surgery (LECS) and non-exposed wall-inversion surgery (NEWS) are also possible now. Reports of these approaches show good results...
December 2017: Current Treatment Options in Gastroenterology
https://www.readbyqxmd.com/read/28904301/a-case-of-gastric-lipoma-resected-by-endoscopic-submucosa-dissection-with-difficulty-in-preoperative-diagnosis
#11
Mizue Ichinose, Takuto Hikichi, Yukiko Kanno, Naohiko Gunji, Masashi Fujita, Masahito Kuroda, Kumiko Terashima, Yoshinori Sato, Satoshi Kawana, Yuko Hashimoto, Hiromasa Ohira, Masayuki Miyata
A 66-year-old man was referred to our hospital with an increasing subepithelial lesion in the gastric antrum. Using esophagogastroduodenoscopy, a tumor with a steep, 20-mm-high rise protruding in the lumen was observed. The mucosal surface of the tumor was reddish, with ulcers forming at the base. Moreover, the tumor was mobile and soft. A biopsy specimen was taken from the ulcer, but tumor tissue was not collected from the submucosa. Endoscopic ultrasonography (EUS) showed a high echoic mass in the submucosa...
September 14, 2017: Fukushima Journal of Medical Science
https://www.readbyqxmd.com/read/28882576/endoscopic-features-and-clinical-outcomes-of-colorectal-mucosa-associated-lymphoid-tissue-lymphoma
#12
Min Kyung Jeon, Hoonsub So, Jooryung Huh, Hee Sang Hwang, Sung Wook Hwang, Sang Hyoung Park, Dong-Hoon Yang, Kee Don Choi, Byong Duk Ye, Seung-Jae Myung, Suk-Kyun Yang, Jeong-Sik Byeon
BACKGROUND AND AIMS: Colorectal mucosa-associated lymphoid tissue (MALT) lymphoma is a rare disease. The purpose of this study was to investigate the clinical and endoscopic features of colorectal MALT lymphoma. METHODS: Patients diagnosed with colorectal MALT lymphoma at Asan Medical Center from 2002 to 2016 were eligible. Medical records were reviewed to investigate clinical features and treatment outcomes. Endoscopic pictures were assessed to characterize the endoscopic features of colorectal MALT lymphoma...
September 4, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28868481/the-role-of-endoscopic-ultrasound-in-the-diagnostic-assessment-of-subepithelial-lesions-of-the-upper-gastrointestinal-tract
#13
Francisca Dias de Castro, Joana Magalhães, Sara Monteiro, Sílvia Leite, José Cotter
INTRODUCTION: The identification of subepithelial lesions is a relatively frequent finding at endoscopy however their natural history is not well known. Our aim was to analyze the role of endoscopic ultrasound (EUS) in the diagnostic approach of subepithelial lesions of the upper gastrointestinal tract. METHODS: Retrospective study which included 324 patients undergoing upper radial EUS for evaluation of subepithelial lesions from 2008 to 2014. The EUS features, presumptive diagnosis and management decision were analyzed...
November 2016: GE Portuguese Journal of Gastroenterology
https://www.readbyqxmd.com/read/28865842/lung-fibrosis-associated-soluble-mediators-and-bronchoalveolar-lavage-from-idiopathic-pulmonary-fibrosis-patients-promote-the-expression-of-fibrogenic-factors-in-subepithelial-lung-myofibroblasts
#14
Evangelos Bouros, Eirini Filidou, Konstantinos Arvanitidis, Dimitrios Mikroulis, Paschalis Steiropoulos, George Bamias, Demosthenes Bouros, George Kolios
Idiopathic pulmonary fibrosis (IPF) is characterized by infiltration of inflammatory cells, excessive collagen production and accumulation of myofibroblasts. We explored the possible role of subepithelial lung myofibroblasts (SELMs) in the development of fibrosis in IPF. SELMs, isolated from surgical specimens of healthy lung tissue, were cultured with pro-inflammatory factors or bronchoalveolar lavage fluid (BALF) from patients with IPF or idiopathic non-specific interstitial pneumonia (iNSIP) and their fibrotic activity was assessed...
October 2017: Pulmonary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28838783/esophageal-adenocarcinoma-10-years-after-surgical-resection%C3%A2-of-barrett-s-esophagus-unusual-presentation-as%C3%A2-subepithelial-tumor
#15
Andreas Probst, Tina Schaller, Helmut Messmann
No abstract text is available yet for this article.
August 22, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28836514/ectopic-pancreas-in-the-upper-gastrointestinal-tract-is-endosonographic-diagnosis-reliable-data-from-the-german-endoscopic-ultrasound-registry-and-review-of-the-literature
#16
Uwe Gottschalk, Christoph F Dietrich, Christian Jenssen
BACKGROUND: Ectopic pancreas (EP) belongs to the most frequent subepithelial lesions (SELs) of the upper gastrointestinal (GI) tract. In the majority of cases, it is detected incidentally. Differential diagnosis from mesenchymal subepithelial tumors may be difficult. METHODS: Among 24,308 endosonographic examinations and interventions, which were prospectively enrolled in the database of the German Endoscopic Ultrasound (EUS) Registry from January 2009 to August 2013, 575 were performed for suspected SELs of the upper GI tract...
August 24, 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/28830136/-the-diagnosis-of-metastatic-malignant-melanoma-incidentally-found-during-a-national-health-screening-endoscopy-a-case-report
#17
Jeong Seok Lee, Su Jin Kim, Dae Hwan Kang, Hyung Wook Kim, Cheol Woong Choi, Su Bum Park, Chang Woo Yeo, Hyeong Jin Kim
Malignant melanoma is one of the most common malignant diseases of the gastrointestinal tract. It has been reported that the malignant melanoma metastasizes not only to the small intestine due to the abundant blood supply, but also to the stomach, colon, and esophagus. Gastrointestinal metastasis is usually suspected depending on the clinical symptoms, as well as based on radiological or endoscopic findings. Imunohistochemical stains, such as Melan-A/Melanoma antigen recognized by T cell-1 or human melanoma black-45, are useful for confirming the diagnosis of malignant melanoma...
August 25, 2017: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/28782509/subepithelial-esophageal-tumors-a-single-center-review-of%C3%A2-resected-and-surveilled-lesions
#18
Don C Codipilly, Hongfei Fang, Jeffrey A Alexander, David A Katzka, Karthik Ravi
BACKGROUND AND AIMS: Subepithelial esophageal tumors (SETs) are frequent incidental findings. Although symptomatic tumors are surgically or endoscopically resected, there is no consensus on the management of asymptomatic esophageal leiomyomas. METHODS: Appropriate International Classification of Diseases, Ninth Revision codes followed by medical record review were used to identify patients with SETs from January 1992 to March 2017, with abstraction of basic demographics, surveillance intervals, and mortality...
August 4, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28707653/canalization-technique-to-obtain-deep-tissue-biopsy-of-gastrointestinal-subepithelial-tumors-as-an-alternative-to-conventional-known-techniques
#19
Ramón Abad-Belando, Modesto J Varas-Lorenzo, Carlos Pons-Vilardell, Xavier Puig-Torrus, Marta Pla-Alcaraz, Antonio Monleón-Getino, Elena Sánchez-Vizcaíno-Mengual
BACKGROUND AND OBJECTIVES: The most accurate technology to detect and diagnose subepithelial tumors (SETs) is the endoscopic ultrasonography (EUS) combined with puncture techniques, such as the endoscopic ultrasonography-guided fine-needle aspiration (EUS-FNA) or the endoscopic ultrasonography-guided fine-needle biopsy. Going further in the improvement of the results of tumor samples obtained endoscopically to diagnose the SETs, the canalization technique guided by miniprobes (MPs) to obtain biopsies of SET could be an alternative to EUS-FNA...
July 13, 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/28702779/clinicopathological-characteristics-of-fallopian-tube-metastases-from-primary-endometrial-cervical-and-nongynecological-malignancies-a-single-institutional-experience
#20
Kiyong Na, Hyun-Soo Kim
This study was aimed at investigating the clinicopathological characteristics of tubal metastases originating from primary endometrial, cervical, and nongynecological malignancies. We performed a 4-year retrospective study in which fallopian tube tissues obtained from 60 patients with tubal metastases were examined. In addition, we compared the number of tubal metastasis cases detected during periods of representative or whole tubal sampling. Twenty-three and 37 tubal metastases were found in cases examined after representative and whole tubal sampling techniques, respectively...
July 13, 2017: Virchows Archiv: An International Journal of Pathology
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