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Tractional retinal detachment

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https://www.readbyqxmd.com/read/28867931/targeted-next-generation-sequencing-analysis-identifies-novel-mutations-in-families-with-severe-familial-exudative-vitreoretinopathy
#1
Xiao-Yan Huang, Hong Zhuang, Ji-Hong Wu, Jian-Kang Li, Fang-Yuan Hu, Yu Zheng, Laurent Christian Asker M Tellier, Sheng-Hai Zhang, Feng-Juan Gao, Jian-Guo Zhang, Ge-Zhi Xu
PURPOSE: Familial exudative vitreoretinopathy (FEVR) is a genetically and clinically heterogeneous disease, characterized by failure of vascular development of the peripheral retina. The symptoms of FEVR vary widely among patients in the same family, and even between the two eyes of a given patient. This study was designed to identify the genetic defect in a patient cohort of ten Chinese families with a definitive diagnosis of FEVR. METHODS: To identify the causative gene, next-generation sequencing (NGS)-based target capture sequencing was performed...
2017: Molecular Vision
https://www.readbyqxmd.com/read/28858062/retinal-detachment-surgery-in-a-pediatric-population-visual-and-anatomic-outcomes
#2
Sarah P Read, Hassan A Aziz, Ajay Kuriyan, Nikisha Kothari, Janet L Davis, William E Smiddy, Harry W Flynn, Timothy G Murray, Audina Berrocal
PURPOSE: Pediatric retinal detachments (RDs) are unique in etiology, anatomy, and prognosis compared with the adult population. The mechanisms of pediatric RD include tractional (TRD), rhegmatogenous retinal detachment, traumatic, and other types, such as exudative or hemorrhagic. This study examined visual and anatomical outcomes of pediatric RD undergoing surgical repair at a single university referral center. METHODS: A retrospective consecutive case series of patients clinically diagnosed and undergoing surgery for RD between birth and 15 years of age from 2002 to 2013 at a single academic institution...
August 28, 2017: Retina
https://www.readbyqxmd.com/read/28857483/intravitreal-gas-for-symptomatic-vitreomacular-adhesion-a-synthesis-of-the-literature
#3
REVIEW
James E Neffendorf, Andrew R H Simpson, David H W Steel, Riti Desai, Dominic A McHugh, Edward Pringle, Timothy L Jackson
Symptomatic vitreomacular adhesion (sVMA) is defined as visual loss secondary to foveal damage from vitreomacular traction (VMT) and includes isolated VMT, impending macular hole (MH), and full-thickness MH with persisting vitreous attachment. Management options include pars plana vitrectomy (PPV), intravitreal ocriplasmin, intravitreal gas injection or observation. This synthesis of the literature aimed to assess the safety and efficacy of intravitreal gas for sVMA. Articles describing patients with VMT or MH treated with intravitreal expansile gas were selected by systematic literature review using MEDLINE, EMBASE, and the Cochrane Database of Controlled Trials (CENTRAL) up to September 2016...
August 31, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28834920/case-report-of-severe-proliferative-retinopathy-in-a-patient-with-congenital-lipodystrophy
#4
Boris Rosin, Tareq Jaouni
PURPOSE: A case report of a patient with severe proliferative retinopathy due to congenital lipodystrophy. METHODS: We reviewed the medical history, imaging, and surgical procedures of a 25-year-old woman with a history of congenital lipodystrophy, presenting with bilateral combined tractional and exudative retinal detachment, poorly controlled diabetes mellitus, and extreme dislipidemia. RESULTS: The patient underwent retinal detachment repair surgery both eyes...
August 21, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28828540/full-thickness-macular-hole-associated-with-congenital-simple-hamartoma-of-retinal-pigment-epithelium-cshrpe
#5
Panagiotis Stavrakas, Athanasios Vachtsevanos, Efthymia Karakosta, Nikos Kozeis, Magdalini Triantafylla, Paraschos Tranos
PURPOSE: To report a unique case of congenital simple hamartoma of retinal pigment epithelium (CSHRPE) associated with full-thickness macular hole (FTMH). METHODS: A 14-year-old female with a previous diagnosis of simple hamartoma of retinal pigment epithelium in the left eye presented with a 3-week onset of reduced visual acuity in the same eye. Complete ophthalmological examination with spectral domain ocular coherence tomography (SD-OCT) and autofluorescence imaging was carried out...
August 21, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28810046/aspergillus-endophthalmitis-resulting-in-development-of-retinal-aspergilloma
#6
Lee Kiang, Ashkan Pirouz, Scott Grant, Sean D Adrean, Mehrdad Malihi, Phoebe Lin
A 78-year-old immunocompetent man presented with a 3-month history of painless decreased vision and panuveitis with a macular lesion presumed to be due to endogenous endophthalmitis. He had been treated with systemic, intravenous, and intravitreal antibiotics and antifungal agents as well as intravitreal steroids. A culture from a prior vitrectomy had grown a single colony of Aspergillus thought to be a contaminant. The macular lesion enlarged and caused a tractional retinal detachment. The patient underwent surgery including resection of what appeared to be an invasive retinal aspergilloma, from which polymerase chain reaction and histopathology confirmed Aspergillus fumigatus...
August 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28796149/visual-and-anatomical-outcomes-after-diabetic-traction-and-traction-rhegmatogenous-retinal-detachment-repair
#7
Philip P Storey, Anna Ter-Zakarian, Shannon A Philander, Lisa Olmos de Koo, Meena George, Mark S Humayun, Damien C Rodger, Hossein Ameri
PURPOSE: To evaluate visual and anatomical outcomes of diabetic tractional retinal detachment repaired with pars plana vitrectomy. METHODS: Operative records were used to retrospectively identify all patients with tractional retinal detachments secondary to proliferative diabetic retinopathy surgically repaired with pars plana vitrectomy between November 1, 2009, and January 1, 2015 at the LAC + USC (Los Angeles County + University of Southern California) Medical Center...
August 8, 2017: Retina
https://www.readbyqxmd.com/read/28767551/ocriplasmin-for-vitreomacular-traction-looking-outside-the-macula-a-wide-field-optical-coherence-tomography-study
#8
Matteo G Cereda, Chiara Preziosa, Isabella DʼAgostino, Mariano Cozzi, Ferdinando Bottoni, Marco Pellegrini, Andrea Giani, Giovanni Staurenghi
PURPOSE: To evaluate baseline features and morphologic changes of vitreoretinal adhesion and outer retinal layers outside the macula after intravitreal ocriplasmin injection. To study the relation between vitreous detachment and attenuation of retinal outer segments signal. METHODS: Retrospective cases series of 15 eyes. Each eye was scanned with the 55° wide-field optical coherence tomography lens in 6 different locations, three horizontal B-scan (central, temporal, and nasal) and three vertical B-scan (central, superior, and inferior) at baseline, 1 week, 1 month, 3 months, and 6 months after injection...
August 1, 2017: Retina
https://www.readbyqxmd.com/read/28764684/intraoperative-optical-coherence-tomography-assisted-analysis-of-pars-plana-vitrectomy-for-retinal-detachment-in-morning-glory-syndrome-a-case-report
#9
Lyubomyr M Lytvynchuk, Carl G Glittenberg, Siamak Ansari-Shahrezaei, Susanne Binder
BACKGROUND: The pathogenesis of non-rhegmatogenous retinal detachment (non-RRD) associated with morning glory syndrome (MGS) is not established, as well as best surgical approach to treat RD. Our purpose was to analyse intraoperative optical coherence tomography data (iOCT) in all steps of pars plana vitrectomy (PPV) for non-RRD in MGS, in order to follow pathophysiological aspects of the disease and to understand the tissues behaviour during surgical workflow. CASE PRESENTATION: Intraoperative spectral domain optical coherent tomography (iSD-OCT) assisted PPV using Rescan 700 (Carl Zeiss Meditech, Jena, Germany) with epiretinal membrane (ERM) and internal retinal membrane (ILM) peeling, and air endotamponade was performed on the only eye of a 21 years old female with non-RRD associated with MGS...
August 1, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28731057/idiopathic-macular-holes-and-direction-of-vitreomacular-traction-structural-changes-and-surgical-outcomes
#10
C-Y Tsai, Y-T Hsieh, T-T Lai, C-M Yang
PurposeTo compare the structural changes, clinical course, and treatment outcomes of vertical and horizontal vitreomacular traction (VMT) induced impending macular holes (IMHs) and full-thickness macular holes (FTMHs).MethodsIn this retrospective study, 23 and 32 cases of IMHs and FTMHs, respectively, were analyzed. The IMH cases were divided into two subgroups: IMH with and without foveal detachment. Vitreofoveal traction angles (TAs) between the inner retinal surface and posterior hyaloid were measured from horizontal and vertical optical coherence tomography (OCT) images by using the trigonometric function (the angle equals the arctangent of the height over the base) after adjustments for magnification factors...
July 21, 2017: Eye
https://www.readbyqxmd.com/read/28728160/structural-changes-of-the-macula-on-optical-coherence-tomography-after-vitrectomy-for-proliferative-diabetic-retinopathy
#11
Jong Chan Im, Jong Ho Kim, Dong Ho Park, Jae Pil Shin
PURPOSE: This study aimed to evaluate the relationship between macular structural changes and visual prognosis after pars plana vitrectomy (PPV) for proliferative diabetic retinopathy. METHODS: The study included 60 eyes that had undergone PPV. Macular optical coherence tomography (OCT) findings were classified into 5 groups preoperatively and 10 groups postoperatively. Best-corrected visual acuity (BCVA) were analyzed according to pre- and postoperative OCT. RESULTS: From the preoperative OCT, normal fovea with/without traction, normal fovea with preretinal hemorrhage, and tractional retinal detachment involving fovea showed an increase in BCVA after PPV (all p < 0...
July 21, 2017: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/28723847/blindness-related-to-presumed-retinal-toxicity-after-using-perfluorocarbon-liquid-during-vitreoretinal-surgery
#12
Silvia Méndez-Martínez, Pilar Calvo, Nelson Arturo Rodriguez-Marco, Fernando Faus, Emilio Abecia, Luis Pablo
PURPOSE: To describe the presumed retinal toxicity after using specific batches of perfluorocarbon liquid ALA OCTA (Alamedics, Dornstadt, Germany) in pars plana vitrectomy. METHODS: This is an observational retrospective consecutive case series analyses of patients operated on pars plana vitrectomy for retinal detachment or intraocular lens subluxation, using the 150141 or 200114 batches of perfluorocarbon liquid ALA OCTA as assistance during the surgery in a single center...
July 18, 2017: Retina
https://www.readbyqxmd.com/read/28710187/utility-of-microscope-integrated-optical-coherence-tomography-mioct-in-the-treatment-of-myopic-macular-hole-retinal-detachment
#13
Atul Kumar, Prateek Kakkar, Raghav Dinesh Ravani, Ashish Markan
Macular hole-associated retinal detachment in high myopia is described as a final stage in progression of myopic traction maculopathy (MTM).(1â€"3) Shimada et al(4) described the progressive stages of MTM from macular retinoschisis to serous retinal detachment in high myopia. Stage 4 MTM is characterised as disappearance of retinoschisis with progression to retinal detachment due to macular hole formation. It is hypothesised that vitreoschisis and abnormal vitreo-retinal interface create the premacular tangential traction...
July 14, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28700420/comparison-of-2d-and-3d-video-displays-for-teaching-vitreoretinal-surgery
#14
Nisarg Chhaya, Omar Helmy, Niloofar Piri, Agustina Palacio, Shlomit Schaal
PURPOSE: To compare medical students' learning uptake and understanding of vitreoretinal surgeries by watching either 2D or 3D video recordings. METHODS: Three vitreoretinal procedures (tractional retinal detachment, exposed scleral buckle removal, and four-point scleral fixation of an intraocular lens [TSS]) were recorded simultaneously with a conventional recorder for two-dimensional viewing and a VERION 3D HD system using Sony HVO-1000MD for three-dimensional viewing...
July 11, 2017: Retina
https://www.readbyqxmd.com/read/28690534/a-case-of-rhegmatogenous-retinal-detachment-at-late-stage-following-endogenous-bacterial-endophthalmitis
#15
Daisaku Kimura, Takaki Sato, Hiroyuki Suzuki, Ryohsuke Kohmoto, Masanori Fukumoto, Kensuke Tajiri, Takatoshi Kobayashi, Teruyo Kida, Tsunehiko Ikeda
PURPOSE: To report a case of rhegmatogenous retinal detachment in the late stage, despite the fact that it had previously been halted after intravitreal injection of an antimicrobial agent against endogenous bacterial endophthalmitis (EBE). CASE: This study involved a 62-year-old male who had previously been diagnosed with septicemia due to liver abscess and the detection of Klebsiella pneumoniae in a culture of his liver abscess, and who underwent ophthalmic examination after his conjunctival hyperemia had failed to improve...
May 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28590967/peripheral-retinoschisis-in-intermediate-uveitis
#16
Francesco Pichi, Sunil K Srivastava, Paolo Nucci, Kimberly Baynes, Piergiorgio Neri, Careen Y Lowder
PURPOSE: To examine cases of intermediate uveitis complicated by retinoschisis and review the pathogenetic hypothesis. METHODS: A retrospective chart review of patients with intermediate uveitis. Data were collected at three uveitis referral centers on sex, age, best-corrected visual acuity, degree of vitritis, extent and location of snowbanking, presence of hard exudates, neovascularization, vitreous hemorrhage, and extent and nature of retinal elevations. RESULTS: A series of 23 eyes of 20 patients were examined; patient's age ranged from 10 years to 70 years and follow-up period from 8 months to 6 years...
January 11, 2017: Retina
https://www.readbyqxmd.com/read/28578309/two-staged-en-bloc-excision-of-a-retinal-haemangioma
#17
Mahima Jhingan, Jay Chhablani, Komal Agarwal, Padmaja Kumari Rani
A 31-year-old man presented to us with diminution of vision in the right eye which he noticed since 10 days, with a visual acuity of hand motions only. On examination, festooned pupil and a complicated cataract were noted with no view of the retina. Ultrasonography of the right eye showed retinal detachment in all quadrants with suspected areas of traction and membranes in the vitreous. Left eye examination revealed a normal anterior and posterior segment. Intraoperatively, he underwent a pars plana lensectomy following which an inferior large retinal haemangioma was noted with dilated and tortuous feeder artery and draining vein...
June 3, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28560050/gamma-knife-radiosurgery-for-the-treatment-of-uveal-melanoma-and-uveal-metastases
#18
Margaret M Reynolds, Andrea L Arnett, Ian F Parney, Ravi Kumar, Nadia N Laack, Patrick R Maloney, Timothy F Kozelsky, Yolanda I Garces, Robert L Foote, Jose S Pulido
BACKGROUND: This study retrospectively analyzed outcomes for patients undergoing gamma knife radiosurgery (GKR) for uveal melanoma (UM) and intraocular metastases. METHODS: Patients who underwent GKR for UM or intraocular metastases between 1/1/1990 and 6/1/2015 at Mayo Clinic, Rochester, MN, USA, were retrospectively analyzed. RESULTS: Eleven patients (11 eyes) had UM while seven patients (7 eyes) had intraocular metastases. Patients with UM were followed for a median of 19...
2017: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/28558009/association-between-aqueous-humor-and-vitreous-fluid-levels-of-th17-cell-related-cytokines-in-patients-with-proliferative-diabetic-retinopathy
#19
Masaru Takeuchi, Tomohito Sato, Yutaka Sakurai, Manzo Taguchi, Kozo Harimoto, Yoko Karasawa, Masataka Ito
Inflammation is known to be involved in the progression of diabetic retinopathy. We have recently reported that vitreous levels of IL-4, IL-17A, IL-22, IL-31, and TNFα are higher than the respective serum levels in proliferative diabetic retinopathy (PDR) patients, and that vitreous levels of these cytokines are higher in PDR than in other non-inflammatory vitreoretinal diseases or uveitis associated with sarcoidosis. In the present study, we investigated inflammatory cytokines including Th17 cell-related cytokines in aqueous humor samples obtained from eyes with PDR, and analyzed the association between the aqueous humor and vitreous fluid levels of individual cytokines...
2017: PloS One
https://www.readbyqxmd.com/read/28549308/climate-and-the-eye-case-crossover-analysis-of-retinal-detachment-after-exposure-to-ambient-heat
#20
MULTICENTER STUDY
Nathalie Auger, Marc-André Rhéaume, Marianne Bilodeau-Bertrand, Tina Tang, Tom Kosatsky
BACKGROUND: Retinal detachment is an important cause of visual loss, but the association with outdoor heat exposure has not been studied. Our objective was to determine the relationship between acute exposure to high outdoor temperature and risk of retinal detachment. MATERIALS AND METHODS: We analysed 14,302 individuals with inpatient procedures for retinal detachment from April through September between 2006 and 2013 in the province of Quebec, Canada. Using a time-stratified case-crossover study design, we examined the association of retinal detachment with outdoor summer temperature the preceding week...
August 2017: Environmental Research
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