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Tractional retinal detachment

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https://www.readbyqxmd.com/read/29146307/long-term-visual-outcomes-and-safety-profile-of-27-gauge-pars-plana-vitrectomy-for-posterior-segment-disease
#1
M Ali Khan, Alexander Kuley, Christopher D Riemann, Maria H Berrocal, Rohit R Lakhanpal, Jason Hsu, Arunan Sivalingam, Allen C Ho, Carl D Regillo
PURPOSE: To report longer-term outcomes of 27-gauge pars plana vitrectomy (PPV) in eyes with posterior segment disease. DESIGN: Multicenter, retrospective, interventional case series. PARTICIPANTS: A total of 390 eyes of 360 patients undergoing 27-gauge PPV for a vitreoretinal surgery indication. INTERVENTION: Three-port, transconjunctival, 27-gauge PPV. MAIN OUTCOME MEASURES: Change in visual acuity (VA) and occurrence of intraoperative and postoperative complications with a minimum follow-up of 365 days...
November 13, 2017: Ophthalmology
https://www.readbyqxmd.com/read/29133665/a-rare-case-of-bilateral-tractional-retinal-detachment-following-snakebite
#2
Nicey Roy Thomas, Debmalya Das, Kumar Saurabh, Rupak Roy
A 13-year-old female presented with diminution of vision in both eyes for 3 months following snakebite. Best-corrected visual acuities were hand movement in both eyes. Fundoscopy showed vitreous hemorrhage, and B-scan ultrasonography revealed an underlying tractional retinal detachment (TRD) involving the macula in both eyes. Patient underwent 25-gauge pars plana vitrectomy in conjunction with belt buckling, endolaser, and silicone oil tamponade in the left eye. At 6 weeks postoperatively, best-corrected visual acuity of the left eye was noted to be 20/200 with settled TRD and attached retina...
November 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29125779/outcomes-of-recurrent-retinal-detachment-surgery-following-pars-plana-vitrectomy-for-rhegmatogenous-retinal-detachment
#3
Vikas Ambiya, Padmaja Kumari Rani, Raja Narayanan, Divya Balakrishnan, Jay Chhablani, Subhadra Jalali, Mudit Tyagi, Rajeev Reddy Pappuru
AIM: To study the anatomical and functional outcomes of recurrent retinal detachment (RD) surgery following pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment. METHODS: Retrospective analysis of 133 consecutive cases of recurrent RD. INCLUSION CRITERIA: age ≥18 years, recurrent RD following PPV ± encircling band for rhegmatogenous RD. EXCLUSION CRITERIA: age <18 years, post-endophthalmitis/tractional/exudative/combined RD, post-scleral buckle, primary surgery done at another institute...
November 10, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/29117066/predictive-factors-of-surgical-outcomes-in-vitrectomy-for-myopic-traction-maculopathy
#4
Kyoko Hattori, Keiko Kataoka, Jun Takeuchi, Yasuki Ito, Hiroko Terasaki
PURPOSE: To assess predictive factors and surgical outcomes for myopic traction maculopathy. METHODS: This retrospective observational case study enrolled 73 patients who underwent vitrectomy for myopic traction maculopathy. The 79 eyes obtained from our study sample were divided into 4 types: retinoschisis, lamellar macular hole (lamellar MH), foveal retinal detachment (FRD), and FRD + lamellar MH, or into 2 types according to the presence of FRD preoperatively...
November 7, 2017: Retina
https://www.readbyqxmd.com/read/29101498/surgical-treatments-for-fibrous-tissue-extending-to-the-posterior-retina-in-eyes-with-familial-exudative-vitreoretinopathy
#5
Mari Takahashi, Tadashi Yokoi, Satoshi Katagiri, Tomoyo Yoshida-Uemura, Sachiko Nishina, Noriyuki Azuma
PURPOSE: To describe the clinical features and surgical outcomes of macular dragging or tractional retinal detachment that occurred as a result of fibrovascular tissue (FT) progression toward the posterior retina in eyes with familial exudative vitreoretinopathy (FEVR). METHODS: The medical records of 4 patients (2 girls, 2 boys) with FEVR were reviewed retrospectively. RESULTS: All 4 patients had retinal dragging or radial retinal folds with FT in the peripheral retina in at least 1 eye at the initial visit...
November 3, 2017: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29090053/pneumatic-vitreolysis-for-management-of-symptomatic-focal-vitreomacular-traction
#6
REVIEW
Clement K Chan, Calvin E Mein, Jason N Crosson
Pneumatic vitreolysis (PVL) is the intravitreal injection of a small quantity of expansile gas for the purpose of achieving focal vitreomacular traction (VMT) release for eyes with symptomatic VMT, or inducing VMT release and closure of the macular defect for eyes with a small stage-2 macular hole (MH). Initially, there was limited interest in this technique upon its introduction for clinical treatment in human eyes in 1993. With the advent of optical coherence tomography allowing detailed observation of vitreomacular interface changes and rising importance of medical economics in recent years, there has been increasing interest in PVL, a low-cost procedure for managing symptomatic VMT...
October 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/29071469/ultrastructural-analyses-of-internal-limiting-membrane-excised-from-highly-myopic-eyes-with-myopic-traction-maculopathy
#7
Reiji Yokota, Akito Hirakata, Nobutsugu Hayashi, Kazunari Hirota, Tosho Rii, Yuji Itoh, Tadashi Orihara, Makoto Inoue
PURPOSE: To evaluate the ultrastructure of the internal limiting membranes (ILMs) excised during vitrectomy from highly myopic eyes with myopic traction maculopathy (MTM). The clinical findings before and after the vitrectomy were compared. METHODS: Seven eyes of 7 patients with macular retinoschisis were studied. Four of these eyes also had a foveal detachment but without a retinal break. All the eyes underwent vitrectomy with the creation of a posterior vitreous detachment and ILM peeling...
October 25, 2017: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29071374/wagner-syndrome-anatomic-functional-and-genetic-characterization-of-a-portuguese-family
#8
Joana R Araújo, João Tavares-Ferreira, Sérgio Estrela-Silva, Paulo Rocha, Elisete Brandão, Pedro Alves Faria, Fernando Falcão-Reis, Amândio Rocha-Sousa
PURPOSE: To report the clinical (anatomic and functional) and genetic findings of Wagner Syndrome (WS) in a Portuguese family. METHODS: Nine members of the family agreed to be examined. All had complete clinical eye examinations. The proband and selected patients underwent color fundus photography, spectral domain optical coherence tomography (SD-OCT), automatic static white-on-white computerized perimetry, and electrophysiology assessment (flash ERG, multifocal(mf) ERG and dark adaptometry)...
October 25, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29070939/epiretinal-membrane-in-a-subject-after-transvitreal-delivery-of-palucorcel-cnto-2476
#9
Rand Spencer, Steven Fisher, Geoffrey P Lewis, Terri Malone
BACKGROUND: A 70-year-old woman with retinitis pigmentosa experienced an epiretinal membrane (ERM) formation and a tractional retinal detachment (RD) following subretinal administration of palucorcel (CNTO 2476), a novel human umbilical tissue-derived cell-based therapy, as part of a Phase I study. The clinical course and results of a histologic examination of the ERM, which was peeled during surgery to repair the RD, are described here. METHODS: In this open-label, first-in-human, Phase I study (NCT00458575), two of seven subjects developed RD, with an ERM formation reported in a woman receiving a targeted dose of 3...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29043092/twenty-seven-gauge-vitrectomy-for-combined-tractional-and-rhegmatogenous-retinal-detachment-involving-the-macula-associated-with-proliferative-diabetic-retinopathy
#10
Yousef J Cruz-Iñigo, María H Berrocal
BACKGROUND: To report our experience using 27-gauge pars plana vitrectomy (PPV) system for treating patients with combined tractional and rhegmatogenous retinal detachments (CTRRD) involving the macula associated with proliferative diabetic retinopathy (PDR). METHODS: Retrospective noncomparative interventional cases series of 12 patients with CTRRD associated with PDR who underwent 3-port, transconjunctival 27-gauge PPV by a single surgeon. Main outcome measures were change in Snellen best corrected visual acuity (BCVA) and occurrence of intra- and post-operative complications...
2017: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/29023269/all-probe-vitrectomy-dissection-techniques-for-diabetic-tractional-retinal-detachments-lift-and-shave
#11
María H Berrocal
To describe a technique to relieve traction, remove fibrovascular tissue, and reattach the retina in cases of tractional retinal detachment secondary to complications of diabetes using only the vitrectomy probe. PURPOSE: To describe the all-probe lift and shave technique to remove fibrovascular tissue and repair diabetic retinal detachments. Anatomical and visual acuity outcomes with this technique are presented. METHODS: In this single surgeon, retrospective review of a consecutive series of eyes with tractional retinal detachment associated with diabetic retinopathy repaired with probe-only dissection techniques...
October 11, 2017: Retina
https://www.readbyqxmd.com/read/28947815/resveratrol-reverses-the-adverse-effects-of-bevacizumab-on-cultured-arpe-19-cells
#12
Murali Subramani, Murugeswari Ponnalagu, Lekshmi Krishna, Nallathambi Jeyabalan, Priyanka Chevour, Anupam Sharma, Chaitra Jayadev, Rohit Shetty, Nargis Begum, Govindaraju Archunan, Debashish Das
Age-related macular degeneration (AMD) and proliferative diabetic retinopathy (PDR) are one of the major causes of blindness caused by neo-vascular changes in the retina. Intravitreal anti-VEGF injections are widely used in the treatment of wet-AMD and PDR. A significant percentage of treated patients have complications of repeated injections. Resveratrol (RES) is a polyphenol phytoalexin with anti-oxidative, anti-inflammatory and anti-proliferative properties. Hence, we hypothesized that if RES is used in combination with bevacizumab (BEV, anti-VEGF), it could reverse the adverse effects that precipitate fibrotic changes, drusen formation, tractional retinal detachment and so on...
September 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28932485/incontinentia-pigmenti-in-a-child-with-suspected-retinoblastoma
#13
Stephanie J Weiss, Archana Srinivasan, Michael A Klufas, Carol L Shields
BACKGROUND: Incontinentia pigmenti is a rare X-linked dominant syndrome caused by mutation in the NEMO/IKKgamma gene, and characterized by a spectrum of cutaneous, ocular, neurologic and dental abnormalities. In the eye, findings include retinal vascular non-perfusion, occasionally with traction retinal detachment, retinal fibrosis, and retinal pigment epithelium defects. These findings can resemble retinoblastoma, especially when vitreoretinal fibrosis produces leukocoria. CASE REPORT: A 2-month-old girl born full-term presented with leukocoria, suspicious for retinoblastoma...
2017: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/28928264/role-of-ultrasound-biomicroscopy-in-diagnosis-of-ocular-toxocariasis
#14
Qian Chen, Junxiang Gu, Rui Jiang, Min Zhou, Qing Chang
PURPOSE: To investigate ultrasound biomicroscopy (UBM) characteristics of patients with ocular toxocariasis (OT) and to explore the role of UBM in the diagnosis and differential diagnosis of OT. DESIGN: Cross-sectional study. METHODS: 78 eyes of 77 patients clinically consistent with OT and confirmed by serum and/or intraocular antibodies in a single tertiary centre (Fudan University Eye and ENT Hospital, Shanghai) between July 2009 and July 2016 were included in the study...
September 19, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28867931/targeted-next-generation-sequencing-analysis-identifies-novel-mutations-in-families-with-severe-familial-exudative-vitreoretinopathy
#15
Xiao-Yan Huang, Hong Zhuang, Ji-Hong Wu, Jian-Kang Li, Fang-Yuan Hu, Yu Zheng, Laurent Christian Asker M Tellier, Sheng-Hai Zhang, Feng-Juan Gao, Jian-Guo Zhang, Ge-Zhi Xu
PURPOSE: Familial exudative vitreoretinopathy (FEVR) is a genetically and clinically heterogeneous disease, characterized by failure of vascular development of the peripheral retina. The symptoms of FEVR vary widely among patients in the same family, and even between the two eyes of a given patient. This study was designed to identify the genetic defect in a patient cohort of ten Chinese families with a definitive diagnosis of FEVR. METHODS: To identify the causative gene, next-generation sequencing (NGS)-based target capture sequencing was performed...
2017: Molecular Vision
https://www.readbyqxmd.com/read/28858062/retinal-detachment-surgery-in-a-pediatric-population-visual-and-anatomic-outcomes
#16
Sarah P Read, Hassan A Aziz, Ajay Kuriyan, Nikisha Kothari, Janet L Davis, William E Smiddy, Harry W Flynn, Timothy G Murray, Audina Berrocal
PURPOSE: Pediatric retinal detachments (RDs) are unique in etiology, anatomy, and prognosis compared with the adult population. The mechanisms of pediatric RD include tractional (TRD), rhegmatogenous retinal detachment, traumatic, and other types, such as exudative or hemorrhagic. This study examined visual and anatomical outcomes of pediatric RD undergoing surgical repair at a single university referral center. METHODS: A retrospective consecutive case series of patients clinically diagnosed and undergoing surgery for RD between birth and 15 years of age from 2002 to 2013 at a single academic institution...
August 28, 2017: Retina
https://www.readbyqxmd.com/read/28857483/intravitreal-gas-for-symptomatic-vitreomacular-adhesion-a-synthesis-of-the-literature
#17
REVIEW
James E Neffendorf, Andrew R H Simpson, David H W Steel, Riti Desai, Dominic A McHugh, Edward Pringle, Timothy L Jackson
Symptomatic vitreomacular adhesion (sVMA) is defined as visual loss secondary to foveal damage from vitreomacular traction (VMT) and includes isolated VMT, impending macular hole (MH), and full-thickness MH with persisting vitreous attachment. Management options include pars plana vitrectomy (PPV), intravitreal ocriplasmin, intravitreal gas injection or observation. This synthesis of the literature aimed to assess the safety and efficacy of intravitreal gas for sVMA. Articles describing patients with VMT or MH treated with intravitreal expansile gas were selected by systematic literature review using MEDLINE, EMBASE, and the Cochrane Database of Controlled Trials (CENTRAL) up to September 2016...
August 31, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28834920/case-report-of-severe-proliferative-retinopathy-in-a-patient-with-congenital-lipodystrophy
#18
Boris Rosin, Tareq Jaouni
PURPOSE: A case report of a patient with severe proliferative retinopathy due to congenital lipodystrophy. METHODS: We reviewed the medical history, imaging, and surgical procedures of a 25-year-old woman with a history of congenital lipodystrophy, presenting with bilateral combined tractional and exudative retinal detachment, poorly controlled diabetes mellitus, and extreme dislipidemia. RESULTS: The patient underwent retinal detachment repair surgery both eyes...
August 21, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28828540/full-thickness-macular-hole-associated-with-congenital-simple-hamartoma-of-retinal-pigment-epithelium-cshrpe
#19
Panagiotis Stavrakas, Athanasios Vachtsevanos, Efthymia Karakosta, Nikos Kozeis, Magdalini Triantafylla, Paraschos Tranos
PURPOSE: To report a unique case of congenital simple hamartoma of retinal pigment epithelium (CSHRPE) associated with full-thickness macular hole (FTMH). METHODS: A 14-year-old female with a previous diagnosis of simple hamartoma of retinal pigment epithelium in the left eye presented with a 3-week onset of reduced visual acuity in the same eye. Complete ophthalmological examination with spectral domain ocular coherence tomography (SD-OCT) and autofluorescence imaging was carried out...
August 21, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28810046/aspergillus-endophthalmitis-resulting-in-development-of-retinal-aspergilloma
#20
Lee Kiang, Ashkan Pirouz, Scott Grant, Sean D Adrean, Mehrdad Malihi, Phoebe Lin
A 78-year-old immunocompetent man presented with a 3-month history of painless decreased vision and panuveitis with a macular lesion presumed to be due to endogenous endophthalmitis. He had been treated with systemic, intravenous, and intravitreal antibiotics and antifungal agents as well as intravitreal steroids. A culture from a prior vitrectomy had grown a single colony of Aspergillus thought to be a contaminant. The macular lesion enlarged and caused a tractional retinal detachment. The patient underwent surgery including resection of what appeared to be an invasive retinal aspergilloma, from which polymerase chain reaction and histopathology confirmed Aspergillus fumigatus...
August 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
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