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Tractional retinal detachment

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https://www.readbyqxmd.com/read/27847643/novel-perspectives-on-swept-source-optical-coherence-tomography
#1
REVIEW
Fabio Lavinsky, Daniel Lavinsky
Technologies for multimodal digital imaging of vitreoretinal diseases have improved the accuracy of diagnosis and the depth of the knowledge of the mechanisms of disease and their response to treatments. Optic coherence tomography (OCT) has become a mandatory tool for the management and for the follow-up of retinal pathologies. OCT technology evolved in the last two decades from time-domain to spectral domain and recently to the swept-source OCTs (SS-OCT). SS-OCT improved the depth of imaging and the scan speed, thus adding novel algorithms and features such as for vitreous and vitreoretinal interface evaluation, choroid segmentation and mapping, OCT angiography and En-face OCT...
2016: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/27833968/posterior-vitreous-detachment-and-macular-anatomical-changes-a-tomographic-electroretinographic-study
#2
Alin Ştefan Ştefănescu-Dima, Cornelia Andreea Corîci, Maria Rodica Mănescu, Teodor Nicuşor Sas, Maria Iancău, Carmen LuminiŢa Mocanu
AIM: Posterior vitreous detachment (PVD) is a physiological phenomenon due to aging characterized by separation of the vitreous cortex from the retina and may induce a variety of pathological events at the vitreoretinal junction. The aim of this study is to highlight in vivo anatomical and functional changes in early stages of PVD allowing the correct treatment. MATERIAL AND METHODS: Non-consecutive case series; optical coherence tomography (OCT) relies on analyzing the reflectivity of coherent light from different anatomical interfaces within posterior vitreous and retinal histological layers, thus acquiring transverse sections through vitreoretinal interface, sensory retina, retinal pigment epithelium and choroid...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/27832339/vitrectomy-and-scleral-imbrication-in-patients-with-myopic-traction-maculopathy-and-macular-hole-retinal-detachment
#3
Yoshimasa Ando, Akito Hirakata, Arisa Ohara, Reiji Yokota, Tadashi Orihara, Kazunari Hirota, Takashi Koto, Makoto Inoue
PURPOSE: To determine the outcomes of vitrectomy with scleral imbrication in highly myopic eyes with either myopic traction maculopathy (MTM) or macular hole retinal detachment (MHRD). METHODS: The medical records of 17 patients who had undergone vitrectomy with internal limiting membrane (ILM) peeling and scleral imbrication for MTM or MHRD were reviewed. The best-corrected visual acuities (BCVAs), the axial length, the macular hole (MH) closure rate, and the shape of the posterior segment determined by optical coherence tomography were evaluated...
November 10, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/27759858/the-effect-of-bevacizumab-pretreatment-on-the-choice-of-endotamponade-in-diabetic-tractional-retinal-detachment
#4
Mehmet Murat Uzel, Mehmet Citirik, Cagri Ilhan, Merve Inanc
BACKGROUND AND OBJECTIVE: To evaluate the effect of preoperative intravitreal bevacizumab (IVB) (Avastin; Genentech, South San Francisco, CA) injection on the choice of endotamponade at the end of surgery in patients who underwent pars plana vitrectomy (PPV) for diabetic tractional retinal detachment (DTRD). PATIENTS AND METHODS: Seventy-eight patients who had DTRD with macular involvement and underwent PPV by a single surgeon from January 2012 to May 2015 were included...
October 1, 2016: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/27700224/evidence-based-treatment-of-diabetic-retinopathy
#5
Hala El Rami, Rasha Barham, Jennifer K Sun, Paolo S Silva
Diabetic retinopathy (DR) is the most frequent microvascular complication from diabetes and requires annual screening and at least annual follow-up. A systemic approach to optimize blood glucose and blood pressure may halt progression to severe stages of DR and obviate the need for ocular treatment. Although there is evidence of benefit from fenofibrate or intravitreous antiVEGF treatment for eyes with nonproliferative DR (NPDR), these therapies are not standard care for NPDR at this time. Some patients with severe NPDR, especially those with type 2 diabetes, benefit from early panretinal photocoagulation (PRP)...
October 4, 2016: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/27698550/intravitreal-methotrexate-infusion-for-proliferative-vitreoretinopathy
#6
Ama Sadaka, Robert A Sisk, James M Osher, Okan Toygar, Melinda K Duncan, Christopher D Riemann
PURPOSE: The purpose of this study was to evaluate intravitreal methotrexate infusion (IMI) during pars plana vitrectomy (PPV) for retinal detachment in patients with high risk for the development of proliferative vitreoretinopathy (PVR). METHODS: Patients presenting with severe recurrent PVR with tractional retinal detachment and/or a history of severe ocular inflammation were treated with IMI. Clinical outcomes were determined from a retrospective medical chart review...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27680778/complicated-congenital-retinoschisis
#7
Brian T Savoie, Philip J Ferrone
PURPOSE: To describe the treatment and natural history of a patient with complicated congenital retinoschisis. METHODS: A retrospective case report. A 10-month-old boy with congenital retinoschisis presented with tractional retinal detachments and foveal schisis in both eyes. RESULTS: On presentation, vision was decreased in both eyes with presumed amblyopia of the left eye. Funduscopic examination revealed bilateral foveal schisis and tractional retinal detachment involving the macula...
September 27, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27619226/ocriplasmin-for-treatment-of-vitreomacular-traction-an-update
#8
Mohammed Ali Khan, Julia A Haller
Pharmacologic vitreolysis with ocriplasmin, a 27 kilodalton serine protease, is an effective nonsurgical treatment option for vitreomacular traction (VMT). Data from phase III clinical studies, including the Microplasmin for Intravitreal Injection-Traction Release without Surgical Treatment (MIVI-TRUST) and Ocriplasmin for Treatment for Symptomatic Vitreomacular Adhesion Including Macular Hole (OASIS) studies, have demonstrated the treatment efficacy of ocriplasmin for VMT and full-thickness macular hole (FTMH)...
September 12, 2016: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/27616879/the-outcomes-and-prognostic-factors-of-vitrectomy-in-chronic-diabetic-traction-macular-detachment
#9
Muneera A Abunajma, Hassan Al-Dhibi, Emad B Abboud, Yahya Al Zahrani, Essam Alharthi, Abdullah Alkharashi, Nicola G Ghazi
PURPOSE: To investigate the outcomes of pars plana vitrectomy (PPV) for chronic diabetic traction macular detachment (CTMD). METHODS: Ninety-six eyes that underwent PPV for CTMD of at least 6 months duration were retrospectively analyzed. Retinal reattachment rate, final vision, and prognostic factors for poor visual outcome were the main outcome measures. RESULTS: All eyes had long-standing TMD (median 12, range: 6-70 months). The median postoperative follow-up was 15 (range: 3-65) months...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27612846/surgery-for-diabetic-eye-complications
#10
REVIEW
María H Berrocal, Luis A Acaba, Alexandra Acaba
New modalities for the treatment of diabetic eye complications have emerged in the past decade. Nevertheless, many severe diabetic retinopathy complications can only be treated with vitreoretinal surgery. Technological advances in pars plana vitrectomy have expanded the gamut of pathologies that can be successfully treated with surgery. The most common pathologies managed surgically include vitreous opacities and traction retinal detachment. The indications, surgical objectives, adjunctive pharmacotherapy, microincisional surgical techniques, and outcomes of diabetic vitrectomy for proliferative diabetic retinopathy and diabetic tractional retinal detachment will be discussed...
October 2016: Current Diabetes Reports
https://www.readbyqxmd.com/read/27589049/real-world-outcomes-of-ocriplasmin-use-by-members-of-the-british-and-eire-association-of-vitreoretinal-surgeons
#11
R J Haynes, D Yorston, D A H Laidlaw, J Keller, D H W Steel
PurposeTo describe a survey of the use of ocriplasmin by members of the British and Eire Association of VitreoRetinal Surgeons (BEAVRS) for VitreoMacular Traction (VMT) and Full Thickness Macular Hole (FTMH) and compare it to published MIVI TRUST trial data.MethodsAll 173 BEAVRS members were contacted by email in October 2014 requesting data on all cases treated with ocriplasmin up to that date. The total number of cases, FTMH closure rate, VMT release rate and the frequency of adverse events were recorded...
September 2, 2016: Eye
https://www.readbyqxmd.com/read/27555798/idiopathic-horseshoe-like-macular-tear-a-case-report
#12
Masaomi Kubota, Tomohiro Shibata, Hisato Gunji, Hiroshi Tsuneoka
BACKGROUND: Although a few cases with idiopathic horseshoe-like macular tear have been reported, the mechanism remains unknown and a standard treatment has yet to be determined. OBJECTIVE: To report the outcome for a patient with idiopathic horseshoe-like macular tear who underwent vitreous surgery. CASE REPORT: A 65-year-old man with no previous injury or ophthalmic disease presented with abnormal vision in his left eye. Best-corrected visual acuity was 0...
2016: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/27555740/novel-mutations-in-fzd4-and-phenotype-genotype-correlation-in-chinese-patients-with-familial-exudative-vitreoretinopathy
#13
Miao Tang, Xiaoyan Ding, Jiaqing Li, Andina Hu, Miner Yuan, Yu Yang, Zongyi Zhan, Zijing Li, Lin Lu
PURPOSE: To identify novel mutations in the frizzled 4 (FZD4) gene in patients with familial exudative vitreoretinopathy (FEVR) in southern China and to delineate the mutation-associated clinical manifestations. METHODS: Clinical data and genomic DNA were collected from 100 probands and their family members. The coding regions of FZD4 were screened for mutations with PCR and Sanger sequencing. Cosegregation analysis was used to verify suspected variants, and clinical symptoms in the probands were analyzed...
2016: Molecular Vision
https://www.readbyqxmd.com/read/27553815/successful-scleral-buckling-of-late-onset-visual-decrease-in-eye-with-retinal-folds
#14
Yuri Nakayama, Satoshi Katagiri, Tadashi Yokoi, Makiko Ui, Sachiko Nishina, Noriyuki Azuma
PURPOSE: To describe the outcome of scleral buckling to treat radial retinal folds (RFs) that caused a late-onset and sudden visual decrease with impairment of the fovea. METHODS: This is an observational case report. Ophthalmic examinations were performed preoperatively and postoperatively and included measurement of the best-corrected visual acuity (BCVA), fundus examination, fluorescein angiography, focal macular electroretinography (FM-ERG), and spectral-domain optical coherence tomography (OCT)...
October 2016: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/27548269/increased-vitreous-chemerin-levels-are-associated-with-proliferative-diabetic-retinopathy
#15
Jun Li, Wen-Chao Hu, Hui Song, Jing-Na Lin, Xin Tang
PURPOSE: To investigate chemerin in the vitreous bodies of patients with proliferative diabetic retinopathy (PDR) and determine the correlation between the levels of vitreous chemerin and vascular endothelial growth factor (VEGF). METHODS: This study included 17 patients suffering from PDR and vitreous hemorrhage (VH) (group A), 21 patients with PDR and tractional retinal detachment (TRD) (group B) and 25 patients with idiopathic macular holes or preretinal membranes (control group)...
2016: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/27533771/vitreoretinal-surgery-for-patients-with-severe-exudative-and-proliferative-manifestations-of-retinal-capillary-hemangioblastoma-because-of-von-hippel-lindau-disease
#16
Remzi Avci, Sami Yilmaz, Umit Ubeyt Inan, Berkant Kaderli, Sadik Gorkem Cevik
PURPOSE: The evaluation of long-term results of vitreoretinal surgery and retinal capillary hemangioblastoma (RCH) resection in patients with complicated retinal detachment (RD) secondary to RCHs. METHODS: Twelve eyes of 12 patients were operated on with vitreoretinal surgery, including occlusion of afferent and efferent feeder vessels with endodiathermy and endolaser photocoagulation, and subsequent resection of RCHs. The long-term anatomical and visual outcomes were retrospectively evaluated...
August 16, 2016: Retina
https://www.readbyqxmd.com/read/27486893/familial-exudative-vitreoretinopathy-with-a-novel-lrp5-mutation
#17
Maria Pefkianaki, Murat Hasanreisoglu, Sharon F Suchy, Carol L Shields
This report reviews the genetics of familial exudative vitreoretinopathy (FEVR) and describes the identification of a novel variant in the LRP5 gene. A 20-month-old boy presented with reduced visual acuity in the right eye from exudative retinal detachment with mild retinal traction. Fluorescein angiography in the right eye disclosed extensive peripheral retinal non-perfusion and telangiectatic vessels and the left eye showed minimal peripheral non-perfusion. These features were suggestive of FEVR. Treatment with laser photocoagulation and cryotherapy to the region of non-perfusion was performed with resolution of the exudative retinal detachment...
2016: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/27479581/-proliferative-vitreoretinopathy
#18
P Wiedemann, A Bringmann
Proliferative vitreoretinal retinopathy (PVR) is a very severe complication of vitreoretinal surgery. PVR is characterised by a complex cellular reaction. This corresponds to a vitreoretinal wound healing reaction and leads to tractional retinal detachment fixed by membranes. A rational goal of treatment is the removal of active cells and membranes, particularly the whole vitreous body; this can only be achieved surgically.
September 2016: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/27472514/successful-treatment-of-refractory-proliferative-retinopathy-of-incontinentia-pigmenti-by-intravitreal-ranibizumab-as-adjunct-therapy-in-a-4-year-old-child
#19
Mary Ho, Wilson W K Yip, Vesta C K Chan, Alvin L Young
PURPOSE: To describe a case of incontinentia pigmenti with proliferative retinopathy successfully treated by combination of repeated retinal laser photocoagulation and intravitreal ranibizumab injection. METHODS: Single interventional case report of a 4-year-old girl, known case of incontientia pigmenti, first screened at the age of two, presented with proliferative retinopathy. Sole treatment by panretinal laser photocoagulation failed to control the progression of retinal neovascularization...
July 28, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27462263/vitrectomy-for-tractional-retinal-detachment-with-twin-retinal-capillary-hemangiomas-in-a-patient-with-von-hippel-lindau-disease-a-case-report
#20
Hiroyuki Suzuki, Keigo Kakurai, Seita Morishita, Daisaku Kimura, Masanori Fukumoto, Takaki Sato, Teruyo Kida, Mari Ueki, Jun Sugasawa, Tsunehiko Ikeda
PURPOSE: The purpose of this study was to report a case of Von Hippel-Lindau disease (VHL) with twin retinal capillary hemangiomas that was successfully treated by vitreous surgery for tractional retinal detachment following laser photocoagulation. CASE: A 44-year-old male presented at our university hospital after noticing decreased visual acuity in his right eye. The patient had previously undergone multiple operations for cerebellar, thoracic, and lumbar spine hemangioblastomas when he was approximately 19 years old...
May 2016: Case Reports in Ophthalmology
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