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Ocular coherence tomography

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https://www.readbyqxmd.com/read/28546695/retinal-vascular-occlusion-secondary-to-retrobulbar-injection-case-report-and-literature-review
#1
Dhaivat Vasavada, Prabu Baskaran, Seema Ramakrishnan
Retrobulbar injection has been widely practiced as a technique of ocular anesthesia for many decades. Nevertheless, the technique is not free from complications. Vascular occlusion secondary to retrobulbar injection is rare but can be vision threatening. We report a case series of two such patients who presented with poor vision following retrobulbar injection. Fundus showed pale retina with cherry red spot suggestive of central retinal artery occlusion in case 1 and pale disc with sclerosed vessels and multiple superficial hemorrhages suggestive of a combined occlusion of retinal artery and vein in case 2...
January 2017: Middle East African Journal of Ophthalmology
https://www.readbyqxmd.com/read/28546470/ocular-changes-over-60-minutes-in-supine-and-prone-postures
#2
Allison P Anderson, Gautam Babu, Jacob G Swan, Scott D Phillips, Darin A Knaus, Christine M Toutain-Kidd, Michael E Zegans, Abigail M Fellows, Jiang Gui, Jay C Buckey
Some astronauts are returning from long duration spaceflight with structural ocular and visual changes. We investigated both the transient and sustained effects of changes in the direction of the gravity vector acting on the eye using changes in body posture. Intraocular pressure (IOP-Perkins tonometer), ocular geometry (axial length, corneal thickness, and aqueous depth-noncontact biometer), and the choroidal (volume and subfoveal thickness optical coherence tomography) was measured in 10 subjects (5M, 5F)...
May 25, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28542084/effects-of-diquafosol-ophthalmic-solution-on-quality-of-life-in-dry-eye-assessed-using-the-dry-eye-related-quality-of-life-score-questionnaire-effectiveness-in-patients-while-reading-and-using-visual-display-terminals
#3
Tsugiaki Utsunomiya, Atsushi Kawahara, Kazuomi Hanada, Akitoshi Yoshida
PURPOSE: Diquafosol ophthalmic solution improves objective findings in the ocular surface and subjective symptoms in patients with dry eye. The Dry Eye-Related Quality-of-Life Score (DEQS) questionnaire was developed to assess dry eye symptoms and their effects on quality of life. However, because little research using the DEQS has been reported, we evaluated the effects of diquafosol ophthalmic solution on ocular surface findings and quality of life using the DEQS in patients with dry eye...
May 23, 2017: Cornea
https://www.readbyqxmd.com/read/28541267/choroidal-melanoma-sector-melanocytosis-and-retinal-pigment-epithelial-microdetachments-in-birt-hogg-dub%C3%A3-syndrome
#4
Charlotte L Marous, Molly R Marous, R Joel Welch, Jerry A Shields, Carol L Shields
PURPOSE: Birt-Hogg-Dubé Syndrome (BHDS) is a rare autosomal dominant condition that can predispose patients to numerous cutaneous fibrofolliculomas and other cutaneous lesions, pulmonary cysts with spontaneous pneumothorax, and multifocal renal tumors and cancer. The genetic mutations responsible for BHDS are related to tumor suppression and the mammalian target of rapamycin (mTOR) pathway. Previous reports of the ocular findings in BHDS include eyelid fibrofolliculomas, "flecked chorioretinopathy," and one report of choroidal melanoma...
May 22, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28536985/anterior-segment-optical-coherence-tomography-and-retained-vegetal-intraocular-foreign-body-masquerading-as-chronic-anterior-uveitis
#5
Anis Mahmoud, Riadh Messaoud, Fatma Abid, Imen Ksiaa, Melek Bouzayene, Moncef Khairallah
BACKGROUND: The purpose of this single case report was to report the use of anterior segment optical coherence tomography for the diagnosis and management of a retained vegetal intraocular foreign body. RESULTS: A 23-year-old otherwise healthy male presented with a progressive vision loss in the right eye (RE). He reported a mild ocular trauma with a tree leaf 1 year ago followed by recurrent episodes of redness and pain in the RE that partially resolved after a self-medication with topical steroids...
December 2017: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/28532619/traumatic-cyclodialysis-treated-with-transscleral-ciclodiode-laser-anterior-and-posterior-segment-evolution
#6
J González-Martín-Moro, M Castro-Rebollo, J Zarallo-Gallardo, F J Muñoz-Negrete
CASE REPORT: A 35-year-old man suffered a severe hipotension maculopathy after being kicked in his left eye. He presented a broad area of iridodialisis. Gonioscopy, ultrasound biomicroscopy and optic coherence tomography were not able to locate the suspected cyclodialysis. Medical treatment was ineffective. Five months later the patient received transcleral diode laser cyclophotocoagulation with clinical resolution. DISCUSSION: Transscleral diode laser constitutes an effective treatment, with low iatrogenia, that can solve cases of ocular hypotension, even when the location of the cyclodialysis has not been determined...
May 19, 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/28532448/the-effects-of-a-treatment-combination-of-anti-vegf-injections-laser-coagulation-and-cryotherapy-on-patients-with-type-3-coat-s-disease
#7
Songfeng Li, Guangda Deng, Jinghua Liu, Yan Ma, Hai Lu
BACKGROUND: To examined the curative effect of vitreous injection with ranibizumab,laser coagulation and cryotherapy in treating stage 3 Coats' disease with exudative retinal detachment. METHODS: Seventeen patients with stage 3 Coats' disease were enrolled in the study. All eyes were treated with vitreous injection of ranibizumab as initial treatment, and subsequent treatment depended on the absorption of subretinal fluid, Including cryotherapy and laser photocoagulation...
May 22, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28524144/-new-approaches-to-the-treatment-of-keratoconjunctivitis-sicca
#8
T N Safonova, O V Gladkova, I A Novikov, V I Boev, A A Fedorov
A new method has been developed for the treatment of severe forms of keratoconjunctivitis sicca (KCS) that involves the use of an original cyclosporine A (CyA) saturated soft contact lens (SCL) together with preservative-free artificial tears therapy. AIM: to evaluate the effectiveness of the newly developed treatment for KCS based on the use of medical SCL saturated with 0.05% CyA. MATERIAL AND METHODS: The patients (43 men, 60 eyes) with severe KCS were divided into 2 groups...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28520627/posterior-scleral-melanocytosis-a-novel-fundus-finding-masquerading-as-a-choroidal-nevus
#9
Rosa Dolz-Marco, Dov B Sebrow, K Bailey Freund
PURPOSE: To report a case of "posterior scleral melanocytosis," a pigmented lesion of the posterior sclera that clinically resembles a flat choroidal nevus. METHODS: Case report of a patient with posterior scleral melanocytosis. Multimodal imaging, including swept source optical coherence tomography, was used to demonstrate the scleral location of the pigmented lesion and to distinguish its features from a typical choroidal nevus present in the same eye. RESULTS: An 86-year-old woman was seen for regular follow-up for neovascular age-related macular degeneration in her right eye and 2 pigmented lesions in her left eye, both presumed to be choroidal nevi...
May 16, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28513113/retina-and-nerve-fiber-layer-thickness-in-eyes-with-thyroid-associated-ophthalmopathy
#10
Sharon Blum Meirovitch, Igal Leibovitch, Anat Kesler, David Varssano, Amir Rosenblatt, Meira Neuderfer
BACKGROUND: Thyroid-associated ophthalmopathy (TAO) is an inflammatory disease that affects the thyroid gland and the eye orbit. Of patients with TAO, 3%-5% have severe sight-threatening disease due to optic neuropathy Optical coherence tomography (OCT), the non-invasive imaging technology that yields high-resolution cross-sectional images of the retina, provides qualitative and quantitative data on the retina. OBJECTIVES: To apply this technique to quantitatively assess retinal nerve fiber layer (RNFL) and macular ring thicknesses in healthy subjects and in patients with TAO to determine their relationship to the severity of the orbital disease...
May 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/28508380/-optical-coherence-tomography-in-eyes-with-senile-retinoschisis-sd-oct-versus-ultrasound-examinations-and-assessment-of-the-vitreoretinal-interface
#11
A Bringewatt, S Burzer, N Feucht, M Maier
BACKGROUND: In addition to ocular ultrasonography (US), spectral domain optical coherence tomography (SD-OCT) is available in order to diagnose senile retinoschisis (sRS). SD-OCT also allows for classification of posterior vitreous detachment (PVD) in healthy eyes. OBJECTIVES: Reevaluation of the value and additional benefit of both imaging procedures. SD-OCT-based evaluation of PVD stages in sRS patients. MATERIALS AND METHODS: Diagnostic results of 33 eyes in 26 patients with clinical suspicion of sRS were retrospectively analysed...
May 15, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28503436/association-of-choroidal-thickness-with-early-stages-of-diabetic-retinopathy-in-type-2-diabetes
#12
Zhi-Jun Shen, Xiu-Fen Yang, Jun Xu, Chong-Yang She, Wen-Wen Wei, Wan-Lu Zhu, Ning-Pu Liu
AIM: To assess the correlation between choroidal thickness (CT) and the early stages of diabetic retinopathy (DR) in type 2 diabetic patients. METHODS: We divided 83 diabetic patients (51-80 years of age; 50 females) into non diabetic retinopathy group (NDR) and mild/moderate nonproliferative diabetic retinopathy (NPDR) group, and compared them with 26 non-diabetic control subjects (51-78 years of age; 16 females). Subfoveal choroidal thickness (SFCT) and parafoveal choroidal thickness (PFCT) were measured using enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT)...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28499992/segmentation-and-quantification-for-angle-closure-glaucoma-assessment-in-anterior-segment-oct
#13
Huazhu Fu, Yanwu Xu, Stephen Lin, Xiaoqin Zhang, Damon Wing Kee Wong, Jiang Liu, Alejandro Frangi, Mani Baskaran, Tin Aung
Angle-closure glaucoma is a major cause of irreversible visual impairment and can be identified by measuring the anterior chamber angle (ACA) of the eye. The ACA can be viewed clearly through Anterior Segment Optical Coherence Tomography (AS-OCT), but the imaging characteristics and the shapes and locations of major ocular structures can vary significantly among different AS-OCT modalities, thus complicating image analysis. To address this problem, we propose a datadriven approach for automatic AS-OCT structure segmentation, measurement and screening...
May 10, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28499051/safety-and-efficacy-of-ziv-aflibercept-in-the-treatment-of-refractory-diabetic-macular-edema
#14
Mohammed Ashraf, Hassan El Kayal, Ahmed A R Souka
BACKGROUND AND OBJECTIVE: To evaluate the safety and efficacy of ziv-aflibercept (Zaltrap; Sanofi-Aventis, Bridgewater, NJ/Regeneron Pharmaceuticals, Tarrytown, NY) in the treatment of refractory diabetic macular edema (DME). PATIENTS AND METHODS: Retrospective case series looking at the safety of ziv-aflibercept in patients with DME refractory to previous anti-vascular endothelial growth factor (VEGF) therapy. Detailed ophthalmologic examination, best-corrected visual acuity, and optical coherence tomography measurements were performed pre-switch, as well as at each monthly follow-up visit...
May 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28497458/ocular-surface-disease-in-patients-under-topical-treatment-for-glaucoma
#15
Francisco Pérez-Bartolomé, Jose M Martínez-de-la-Casa, Pedro Arriola-Villalobos, Cristina Fernández-Pérez, Vicente Polo, Julián García-Feijoó
PURPOSE: To examine the relationship between ocular surface disease (OSD) and topical antiglaucoma therapy. METHODS: A total of 211 eyes of 211 patients with open-angle glaucoma or ocular hypertension on topical medication were recruited over 10 months. Controls were 51 eyes of 51 healthy age- and sex-matched volunteers. In each patient, we recorded the intraocular pressure-lowering eyedrops used, the number of medications used, and daily and cumulative preservative concentrations (PC)...
May 10, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28494517/exploration-of-peripapillary-vessel-density-in-highly-myopic-eyes-with-peripapillary-intrachoroidal-cavitation-and-its-relationship-with-ocular-parameters-using-optical-coherence-tomography-angiography
#16
Chen Qiuying, He Jiangnan, Hua Yihong, Fan Ying
IMPORTANCE: Identifying changes of peripapillary vessel density in highly myopic eyes with peripapillary intrachoroidal cavitation (PICC) by optical coherence tomography angiography (OCTA). BACKGROUND: To investigate peripapillary vessel density and its relationship with other ocular parameters in highly myopic eyes with PICC. DESIGN: This was a hospital-based, cross-sectional study. PARTICIPANTS: Thirty-five highly myopic eyes with PICC, 46 highly myopic eyes without PICC and 36 normal eyes were included in this study...
May 11, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28493931/asymptomatic-carotid-artery-stenosis-and-retinal-nerve-fiber-layer-thickness-a-community-based-observational-study
#17
Dandan Wang, Yang Li, Yong Zhou, Cheng Jin, Qi Zhao, Anxin Wang, Shouling Wu, Wen Bin Wei, Xingquan Zhao, Jost B Jonas
PURPOSE: To examine whether an abnormally thin retinal nerve fiber layer (RNFL) is associated with cerebrovascular insufficiency. DESIGN: Community-based study. METHODS: The Asymptomatic Polyvascular Abnormalities in Community Study included Chinese aged 40+ years and without histories of cerebrovascular incidents or coronary heart disease. Using transcranial Doppler and carotid duplex ultrasound examination, we assessed presence and degree of an intracranial arterial stenosis (ICAS) and extracranial carotid arterial stenosis (ECAS) and we measured the RNFL thickness by spectral-domain optical coherence tomography...
2017: PloS One
https://www.readbyqxmd.com/read/28491467/association-between-asymptomatic-unilateral-internal-carotid-artery-stenosis-and-electrophysiological-function-of-the-retina-and-optic-nerve
#18
Anna Machalińska, Aleksandra Kowalska-Budek, Miłosz Piotr Kawa, Arkadiusz Kazimierczak, Krzysztof Safranow, Marta Kirkiewicz, Grażyna Wilk, Wojciech Lubiński, Piotr Gutowski, Bogusław Machaliński
Purpose. This study was designed to assess retinal and optic nerve bioelectrical function in patients with unilateral asymptomatic but hemodynamically significant internal carotid artery stenosis (ICAS). Methods. Forty-two subjects with a diagnosis of unilateral ICAS and 34 controls were analyzed. Full-field electroretinogram (ERG), pattern electroretinogram (PERG), and pattern visual-evoked potentials, as well as optical coherence tomography and ophthalmological examination, were performed. Data analysis included eyes ipsilateral to ICAS (EIS) and eyes contralateral to ICAS (ECS)...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28490803/effects-of-smoking-and-smoking-abstinence-on-spatial-vision-in-chronic-heavy-smokers
#19
Thiago Monteiro de Paiva Fernandes, Natalia Leandro de Almeida, Natanael Antonio Dos Santos
Cigarette smoke is a complex chemical mixture, involving health-damaging components such as carbon monoxide, ammonia, pyridine, toluene and nicotine. While cognitive functions have been well documented in heavy smokers, spatial vision has been less characterized. In the article, we investigated smoking effects through contrast sensitivity function (CSF), a rigorous procedure that measures the spatial vision. Data were recorded from 48 participants, a group of non-smokers (n = 16), a group of chronic and heavy cigarette smokers (n = 16) and deprived smokers (n = 16); age range 20-45 years...
May 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28490427/effect-of-acute-intraocular-pressure-elevation-on-the-minimum-rim-width-in-normal-ocular-hypertensive-and-glaucoma-eyes
#20
Sourabh Sharma, Tin A Tun, Mani Baskaran, Eray Atalay, Sri Gowtham Thakku, Zhang Liang, Dan Milea, Nicholas G Strouthidis, Tin Aung, Michael Ja Girard
BACKGROUND: To estimate and compare changes in the Bruch's membrane opening-minimum rim width (BMO-MRW) and area in normal, ocular hypertensive and glaucoma eyes following acute elevations in intraocular pressure (IOP). METHODS: The optic nerve heads (ONHs) of 104 subjects (31 normals, 20 ocular hypertension (OHT) and 53 with primary glaucoma) were imaged using Spectral-domain optical coherence tomography (OCT; Spectralis, Heidelberg Engineering, Germany). IOP was raised twice by applying a force (0...
May 10, 2017: British Journal of Ophthalmology
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