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https://www.readbyqxmd.com/read/28166900/effects-of-auditory-and-tactile-warning-on-response-to-visual-hazards-under-a-noisy-environment
#1
Atsuo Murata, Takashi Kuroda, Waldemar Karwowski
A warning signal presented via a visual or an auditory cue might interfere with auditory or visual information inside and outside a vehicle. On the other hand, such interference would be certainly reduced if a tactile cue is used. Therefore, it is expected that tactile cues would be promising as warning signals, especially in a noisy environment. In order to determine the most suitable modality of cue (warning) to a visual hazard in noisy environments, auditory and tactile cues were examined in this study. The condition of stimulus onset asynchrony (SOA) was set to 0ms, 500ms, and 1000ms...
April 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28164936/the-effects-of-acoustic-white-noise-on-the-rat-central-auditory-system-during-the-fetal-and-critical-neonatal-periods-a-stereological-study
#2
Mohammad Saied Salehi, Mohammad Reza Namavar, Amin Tamadon, Raziyeh Bahmani, Mohammad Reza Jafarzadeh Shirazi, Homayoun Khazali, Leila Dargahi, Sareh Pandamooz, Farzad Mohammad-Rezazadeh, Fatemeh Sadat Rashidi
AIM: To evaluate the effects of long-term, moderate level noise exposure during crucial periods of rat infants on stereological parameters of medial geniculate body (MGB) and auditory cortex. MATERIALS AND METHODS: Twenty-four male offspring of 12 pregnant rats were divided into four groups: fetal-to-critical period group, which were exposed to noise from the last 10 days of fetal life till postnatal day (PND) 29; fetal period group that exposed to noise during the last 10 days of fetal life; critical period group, exposed to noise from PND 15 till PND 29, and control group...
January 2017: Noise & Health
https://www.readbyqxmd.com/read/28161157/effect-of-scoparia-dulcis-on-noise-stress-induced-adaptive-immunity-and-cytokine-response-in-immunized-wistar-rats
#3
Loganathan Sundareswaran, Sakthivel Srinivasan, Wankupar Wankhar, Rathinasamy Sheeladevi
BACKGROUND: Noise acts as a stressor and is reported to have impact on individual health depending on nature, type, intensity and perception. Modern medicine has no effective drugs or cure to prevent its consequences. Being an environmental stressor noise cannot be avoided; instead minimizing its exposure or consuming anti-stressor and adaptogens from plants can be considered. OBJECTIVES: The present study was carried out to evaluate the anti-stressor, adaptogen and immunostimulatory activity of Scoparia dulcis against noise-induced stress in Wistar rat models...
February 1, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28152124/structural-and-functional-recovery-following-limited-iatrogenic-macular-detachment-for-retinal-gene-therapy
#4
Matthew P Simunovic, Kanmin Xue, Jasleen K Jolly, Robert E MacLaren
Importance: The early decline and recovery of retinal structure and function following iatrogenic macular detachment for retinal gene therapy is not well characterized in those with relatively preserved central visual function. Here, the recovery of retinal structure and function over the first month following iatrogenic retinal detachment for the delivery of adeno-associated viral vector encoding Rab Escort Protein 1 is described as a part of gene therapy for choroideremia. Objective: To study changes in both retinal structure and function during the first month following iatrogenic macular detachment surgery...
February 2, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28129657/physiological-characterization-of-a-novel-ppar-pan-agonist-2-4-5-6-methylenedioxybenzo-d-thiazol-2-yl-2-methylphenoxy-2-methylpropanoic-acid-mhy2013
#5
Hye Jin An, Bonggi Lee, Dae Hyun Kim, Eun Kyeong Lee, Ki Wung Chung, Min Hi Park, Hyoung Oh Jeong, Sung Min Kim, Kyoung Mi Moon, Ye Ra Kim, Seong Jin Kim, Hwi Young Yun, Pusoon Chun, Byung Pal Yu, Hyung Ryong Moon, Hae Young Chung
Recently, agonists targeting multiple peroxisome proliferator-activated receptors (PPARs) have been developed to improve metabolic disorders and minimize the side effects of selective PPAR agonists such as weight gain and dyslipidemia. We newly synthesized six 2-methyl-2-(o-tolyloxy)propanoic acid derivatives based on the structure of a well-known PPAR pan agonist, bezafibrate. Of six compounds, MHY2013 was screened as the strongest activator of three PPAR subtypes based on protein docking simulation and luciferase assays...
25, 2017: Oncotarget
https://www.readbyqxmd.com/read/28126063/eyeblink-conditioning-with-a-noise-burst-as-unconditioned-stimulus
#6
José L Marcos Malmierca, Azahara Marcos de Vega
BACKGROUND: The aim of this study was to determine if a white noise burst could be used as an effective unconditioned stimulus (US) to produce differential conditioning of eyeblink responses that were recorded as EMG activity of the orbicularis oculi. METHOD: Two fear-relevant stimuli served as conditioned stimuli (CS). An angry woman’s face (CS+) was consistently followed by a white noise burst (US) with 100 dB intensity and 100 milliseconds in duration.  A fearful face of the same woman (CS-) was not followed by the US...
February 2017: Psicothema
https://www.readbyqxmd.com/read/28108342/effects-of-dietary-lactobacillus-plantarum-in-different-treatments-on-growth-performance-and-immune-gene-expression-of-white-shrimp-litopenaeus-vannamei-under-normal-condition-and-stress-of-acute-low-salinity
#7
Xiaoting Zheng, Yafei Duan, Hongbiao Dong, Jiasong Zhang
A 45-day feeding trial followed by an acute stress test of low salinity was done to evaluate effects of Lactobacillus plantarum on growth performance and anti-stress capability of white shrimp (Litopenaeus vannamei). Shrimp were randomly allocated in 15 tanks (100 shrimp per tank) and divided into 5 treatments with 3 replicates. Triplicate tanks were fed with a control diet or diets containing different treatments of L. plantarum (fermentation supernatant (FS), live bacteria (LB), dead bacteria (DB) and cell-free extract (CE) of L...
January 17, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/28080976/respiratory-modulation-of-startle-eye-blink-a-new-approach-to-assess-afferent-signals-from-the-respiratory-system
#8
André Schulz, Thomas M Schilling, Claus Vögele, Mauro F Larra, Hartmut Schächinger
Current approaches to assess interoception of respiratory functions cannot differentiate between the physiological basis of interoception, i.e. visceral-afferent signal processing, and the psychological process of attention focusing. Furthermore, they typically involve invasive procedures, e.g. induction of respiratory occlusions or the inhalation of CO2-enriched air. The aim of this study was to test the capacity of startle methodology to reflect respiratory-related afferent signal processing, independent of invasive procedures...
November 19, 2016: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28059329/demonstration-of-136-db-dynamic-range-capability-for-a-simultaneous-dual-optical-band-caos-camera
#9
Nabeel A Riza, J Pablo La Torre
For the first time, proposed and demonstrated is a simultaneous dual optical band coded access optical sensor (CAOS) camera design suited for extreme contrast multispectral bright target scenarios. Deploying a digital micromirror devices (DMDs)-based time-frequency agile pixels CAOS-mode within a two point detector spatially and spectrally isolating framework, this imager simultaneously and independently detects pixel selective image information for two different broad spectral bands that further undergo independent spectral image data extraction via finer-tuned wavelength filtering using all-optical or CAOS-mode electronic filters...
December 26, 2016: Optics Express
https://www.readbyqxmd.com/read/27991470/air-traffic-controllers-long-term-speech-in-noise-training-effects-a-control-group-study
#10
Maria T P Zaballos, Daniel P Plasencia, María L Z González, Angel R de Miguel, Ángel R Macías
INTRODUCTION: Speech perception in noise relies on the capacity of the auditory system to process complex sounds using sensory and cognitive skills. The possibility that these can be trained during adulthood is of special interest in auditory disorders, where speech in noise perception becomes compromised. Air traffic controllers (ATC) are constantly exposed to radio communication, a situation that seems to produce auditory learning. The objective of this study has been to quantify this effect...
November 2016: Noise & Health
https://www.readbyqxmd.com/read/27956721/otologic-and-audiologic-outcomes-in-pediatric-patients-with-velo-cardio-facial-22q11-deletion-syndrome
#11
Forest W Weir, Sarah A Wallace, David R White, Jonathan L Hatch, Shaun A Nguyen, Ted A Meyer
OBJECTIVE: The focus of this study was to evaluate the prevalence, type, and severity of hearing impairment in patients with velo-cardio-facial syndrome (VCFS) and to compare these characteristics with patient demographics and other otologic factors. STUDY DESIGN: Retrospective analysis of the AudGen Database. SETTING: Tertiary academic referral center. PATIENTS: Pediatric patients in AudGenDB with a diagnosis of velo-cardio-facial syndrome or DiGeorge syndrome...
January 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/27942464/short-term-caloric-restriction-in-db-db-mice-improves-myocardial-function-and-increases-high-molecular-weight-hmw-adiponectin
#12
X Julia Xu, Erma Babo, Fuzhong Qin, Dominique Croteau, Wilson S Colucci
BACKGROUND: Obesity and metabolic syndrome lead to the development of metabolic heart disease (MHD) that is characterized by left ventricular hypertrophy (LVH), diastolic dysfunction, and increased mitochondrial ROS. Caloric restriction (CR) is a nutritional intervention that protects against obesity, diabetes, and cardiovascular disease. Healthy adipose tissue is cardioprotective via releasing adipokines such as adiponectin. We tested the hypothesis that CR can ameliorate MHD and it is associated with improved adipose tissue function as reflected by increased circulating levels of high molecular weight (HMW) adiponectin and AMP-activated protein kinase (AMPK) in db/db mice...
December 2016: IJC Metabolic & Endocrine
https://www.readbyqxmd.com/read/27897448/diagnostic-ability-of-automated-pupillography-in-glaucoma
#13
Harsha L Rao, Sujatha V Kadambi, Pooja Mehta, Srilakshmi Dasari, Narendra K Puttaiah, Zia S Pradhan, Dhanraj A S Rao, Rohit Shetty
PURPOSE: To evaluate the diagnostic ability of automated pupillography measurements in glaucoma and study the effect of inter-eye asymmetry in glaucomatous damage on the diagnostic ability. METHODS: In an observational, cross-sectional study, 47 glaucoma patients and 42 control subjects underwent automated pupillography using a commercially available device. Diagnostic abilities of the pupillary response measurements were evaluated using area under receiver operating characteristic (ROC) curves (AUC) and sensitivities at fixed specificities...
November 29, 2016: Current Eye Research
https://www.readbyqxmd.com/read/27897127/effects-of-noise-exposure-on-the-auditory-function-of-ovariectomized-rats-with-estrogen-deficiency
#14
Xujun Hu, Ying Wang, Chi Chuen Lau
OBJECTIVE: The benefits of estrogen for the auditory function of women depend on a number of factors. In this study, we aimed to examine the impact of noise trauma on the auditory function of ovariectomized rats with estrogen deficiency. MATERIALS AND METHODS: Twenty-eight young, female Sprague-Dawley rats were assigned to three groups (OVX+N, OVX-N, Sham+N). Rats in the OVX+N group and the OVX-N group underwent bilateral ovariectomy (OVX); the OVX+N group alone was also exposed to white noise (N) of 115 dB SPL for 8 hours a day over 14 days...
November 28, 2016: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/27878557/simple-reaction-time-for-broadband-sounds-compared-to-pure-tones
#15
Josef Schlittenlacher, Wolfgang Ellermeier, Gül Avci
Although many studies have explored the relation between reaction time (RT) and loudness, including effects of intensity, frequency, and binaural summation, comparable work on spectral summation is rare. However, most real-world sounds are not pure tones and typically have bandwidths covering several critical bands. Since comparing to a 1-kHz pure tone, the reference tone, is important for loudness measurement and standardization, the present work focuses on comparing RTs for broadband noise to those for 1-kHz pure tones in three experiments using different spectral and binaural configurations...
November 22, 2016: Attention, Perception & Psychophysics
https://www.readbyqxmd.com/read/27849549/signal-to-noise-ratio-analysis-of-a-phase-sensitive-voltmeter-for-electrical-impedance-tomography
#16
Ethan K Murphy, Mohammad Takhti, Joseph Skinner, Ryan J Halter, Kofi Odame
In this paper, thorough analysis along with mathematical derivations of the matched filter for a voltmeter used in electrical impedance tomography systems are presented. The effect of the random noise in the system prior to the matched filter, generated by other components, are considered. Employing the presented equations allow system/circuit designers to find the maximum tolerable noise prior to the matched filter that leads to the target signal-to-noise ratio (SNR) of the voltmeter, without having to over-design internal components...
November 10, 2016: IEEE Transactions on Biomedical Circuits and Systems
https://www.readbyqxmd.com/read/27805061/harmine-induces-adipocyte-thermogenesis-through-rac1-mek-erk-chd4-axis
#17
Tao Nie, Xiaoyan Hui, Liufeng Mao, Baoming Nie, Kuai Li, Wei Sun, Xuefei Gao, Xiaofeng Tang, Yong Xu, Baishan Jiang, Zhengcao Tu, Peng Li, Ke Ding, Weiping Han, Shaoping Zhang, Aimin Xu, Sheng Ding, Pentao Liu, Adam Patterson, Garth Cooper, Donghai Wu
Harmine is a natural compound possessing insulin-sensitizing effect in db/db diabetic mice. However its effect on adipose tissue browning is unknown. Here we reveal that harmine antagonizes high fat diet-induced adiposity. Harmine-treated mice gained less weight on a high fat diet and displayed increased energy expenditure and adipose tissue thermogenesis. In vitro, harmine potently induced the expression of thermogenic genes in both brown and white adipocytes, which was largely abolished by inhibition of RAC1/MEK/ERK pathway...
November 2, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27794358/the-effects-of-click-and-masker-spectrum-on-the-auditory-brainstem-response-of-bottlenose-dolphins-tursiops-truncatus
#18
Jason Mulsow, James J Finneran, Dorian S Houser, Robert F Burkard
Two experiments were performed that investigated the effects of (1) click level and (2) continuous broadband noise on the binaural auditory brainstem response (ABR) of normal-hearing and hearing-impaired bottlenose dolphins (Tursiops truncatus). In addition to spectrally uncompensated clicks and noise, stimuli were digitally compensated to achieve "white" spectra (flat spectral density level) or "pink" spectra (spectral density level rolling off at -3 dB/octave). For experiment 1, in all spectral conditions, ABR peak latencies increased and peak amplitudes decreased with decreasing click level, but interwave intervals changed little...
October 2016: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/27775526/eeg-based-prediction-of-epileptic-seizures-using-phase-synchronization-elicited-from-noise-assisted-multivariate-empirical-mode-decomposition
#19
Dongrae Cho, Beomjun Min, Jongin Kim, Boreom Lee
In this study, we examined the phase locking value (PLV) for seizure prediction, particularly, in the gamma frequency band. We prepared simulation data and 65 clinical cases of seizure. In addition, various filtering algorithms including bandpass filtering, empirical mode decomposition, multivariate empirical mode decomposition and noise-assisted multivariate empirical mode decomposition (NA-MEMD) were used to decompose spectral components from the data. Moreover, in the case of clinical data, the PLVs were used to classify between interictal and preictal stages using a support vector machine...
October 19, 2016: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/27754182/db-03-2-renal-sympathetic-denervation-is-still-a-viable-option-for-treating-resistant-hypertension-con
#20
George Bakris
Renal denervation started out as a very promising approach to treat resistant hypertension with a very strong conceptual and basic science frame work from Gerald DiBona's lab and extending into the early non shame clinical studies demonstrating proof of concept in SYMPLICITY HTN-1 and 2. SYMPLICITY-HTN 3 a properly done, sham control trial failed to show a benefit on further reduction of BP compared to the sham group. The conclusion the procedure doesn't work. How could this be-it was clearly effective in animal models but why not in man...
September 2016: Journal of Hypertension
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