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Geriatrics, pain, stroke? Neurology

Roland Nau, Marija Djukic, Manfred Wappler
The care of elderly patients will continue to challenge the healthcare system over the next decades. As a rule geriatric patients suffer from multimorbidities with complex disease patterns, and the ability to cope with everyday life is severely reduced. Treatment is provided by a multiprofessional geriatric team, and the primary goal is improvement of functional status, quality of life in the social environment and autonomy by employing a holistic approach. In Germany geriatric care is provided by physicians from various medical specialties (e...
June 2016: Der Nervenarzt
On Ying Liu, Theodore Malmstrom, Patricia Burhanna, Miriam B Rodin
BACKGROUND: Research on inpatient palliative medicine reports quality-of-life outcomes and selected "hard" outcomes including pain scores, survival, and readmissions. OBJECTIVE: This case study reports the evolution of an inpatient palliative consultation (IPC) team to show how IPC induces culture change in a hospital that previously had no palliative care. DESIGN: Retrospective chart review. SETTING: A Catholic university-affiliated, inner-city hospital...
February 2017: American Journal of Hospice & Palliative Care
Wai Kwong Tang, Huajun Liang, Vincent Mok, Gabor S Ungvari, Ka-Sing Wong
OBJECTIVE: To evaluate the relation between poststroke pain and suicidality (SI) in Chinese patients with first or recurrent stroke. DESIGN: Cross-sectional survey. SETTING: Acute stroke unit of a university-affiliated general hospital. PARTICIPANTS: Patients (N=496) with acute ischemic stroke admitted to the Acute Stroke Unit. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Patients were interviewed 3 months after the index stroke...
May 2013: Archives of Physical Medicine and Rehabilitation
J Robert Swenson, Steve Doucette, Dean Fergusson
OBJECTIVE: To examine whether selective serotonin reuptake inhibitor (SSRI) antidepressants were associated with an increased or decreased risk of cardiovascular adverse events (AEs). METHODS: We conducted a systematic review of randomized controlled trials published between 1967 and May 2005 that treated patients with cardiac disease, diabetes mellitus, stroke, geriatric age, nicotine dependence, alcoholism, HIV infection, and obesity. We defined serious AEs as death due to a cardiovascular cause, heart failure, stroke, transient ischemic attack, and myocardial infarction...
December 2006: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
Johanne Desrosiers, Réjean Hébert, Hélène Payette, Pierre-Michel Roy, Michel Tousignant, Sylvie Côté, Lise Trottier
This study compared the changes in some bio-psychosocial variables (functional independence, nutritional risk, pain, balance and walking, grip strength, general well-being, psychiatric profile, perception of social support, leisure satisfaction, and caregivers' feeling of burden) in four categories of clients during their program at a geriatric day hospital (GDH). The study also evaluated whether or not improvements, if any, were maintained 3 months after discharge. One-hundred-and-fifty-one people, categorized by primary reason for admission, were assessed at the GDH with reliable and valid tools, at admission and at discharge...
2004: Canadian Journal on Aging, la Revue Canadienne du Vieillissement
D A Le, S A Lipton
The N-methyl-D-aspartate (NMDA) receptor complex is a subtype of glutamate receptor and its dysfunction is involved in many neurological disorders associated with aging, including chronic pain, depression, stroke and Parkinson's disease. Multiple clinical trials using NMDA receptor antagonists have been aborted mainly due to the severe psychomimetic adverse effects of these drugs that occur before concentrations can reach an adequate level in the brain. In this review, we present the evidence that clinically safer NMDA antagonists such as memantine and nitroglycerin, and the combination drug nitro-memantine, are promising as drugs in treating neurodegenerative diseases...
2001: Drugs & Aging
B P Imbimbo, W M Troetel, P Martelli, F Lucchelli
OBJECTIVES: To evaluate the efficacy and safety of eptastigmine as a treatment for patients with mild-to-moderate Alzheimer's disease (AD). PATIENTS AND METHODS: The study was designed as a randomized, double-blind, placebo-controlled, parallel-group study. It was performed in 26 Italian and American geriatric and neurological centers. The study group comprised 349 outpatients with a diagnosis of probable AD according to the criteria of the National Institute of Neurological and Communicative Disorders and Stroke and the AD and Related Disorders Association...
January 2000: Dementia and Geriatric Cognitive Disorders
F U Steinberg
Eighty percent of survivors (approximately 140,000 per year) have a significant impairment of neurologic function, but are not totally disabled. These are the patients who may benefit from rehabilitation. Rehabilitation cannot restore the activity of paralyzed muscles, but it will train the patient to utilize remaining functions to compensate for what has been lost.
March 1986: Geriatrics
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