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https://www.readbyqxmd.com/read/29776002/the-chaos-of-hospitalisation-for-patients-with-critical-limb-ischaemia-approaching-major-amputation
#1
Susan Monaro, Sandra West, Jana Pinkova, Janice Gullick
AIMS AND OBJECTIVES: To illuminate the hospital experience for patients and families when major amputation has been advised for critical limb ischaemia (CLI). BACKGROUND: CLI creates significant burden to the health system and the family, particularly as the person with CLI approaches amputation. Major amputation is often offered as a late intervention for CLI in response to the marked deterioration of an ischaemic limb, and functional decline from reduced mobility, intractable pain, infection and/or toxaemia...
May 18, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29775993/postnatal-psychosocial-assessment-and-clinical-decision-making-a-descriptive-study
#2
Deborah Sims, Cathrine Fowler
AIM: The aim of this study is to describe experienced child and family health nurses' clinical decision-making during a postnatal psychosocial assessment. BACKGROUND: Maternal emotional wellbeing in the postnatal year optimises parenting and promotes infant development. Psychosocial assessment potentially enables early intervention and reduces the risk of a mental disorder occurring during this time of change. Assessment accuracy, and the interventions used are determined by the standard of nursing decision-making...
May 18, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29775969/the-scale-on-community-care-perceptions-scope-for-nursing-students-a-development-and-psychometric-validation-study
#3
Margriet van Iersel, Rien de Vos, Corine Latour, Paul A Kirschner, Wilma Scholte Op Reimer
The aim of this study was to develop a valid instrument to measure student nurses' perceptions of community care (SCOPE). DeVellis' staged model for instrument development and validation was used. Scale construction of SCOPE was based on existing literature. Evaluation of its psychometric properties included exploratory factor analysis and reliability analysis. After pilot-testing, 1062 bachelor nursing students from six institutions in the Netherlands (response rate 81%) took part in the study. SCOPE is a 35-item scale containing: background variables, 11 measuring the affective component, 5 measuring community care perception as a placement, 17 as a future profession, and 2 on the reasons underlying student preference...
May 11, 2018: Nurse Education in Practice
https://www.readbyqxmd.com/read/29775852/biomimetic-magnetoelectric-nanocrystals-synthesized-by-polymerization-of-heme-as-advanced-nanomaterials-for-biosensing-application
#4
Jeong Eun Hyeon, Da Woon Jeong, Young Jin Ko, Seung Wook Kim, Chulhwan Park, Sung Ok Han
Regardless of the malaria disease risk, the malaria parasite Plasmodium falciparum has an interesting mechanism. During its growth within the red blood cell, toxic free heme is converted into an insoluble crystalline form called the malaria pigment, or hemozoin. In particular, natural hemozoin nanocrystals can provide multiple applications in biosensing fields for health care and diagnosis as similar to artificial metal nanoparticles. In this study, the heme was biologically synthesized and polymerized by Corynebacterium glutamicum and final polymer was applied as a biomimetic conductive biopolymer...
May 10, 2018: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29775641/surviving-out-of-hospital-cardiac-arrest-the-neurological-and-functional-outcome-and-health-related-quality-of-life-one-year-later
#5
Marjaana Tiainen, Jukka Vaahersalo, Markus B Skrifvars, Johanna Hästbacka, Juha Grönlund, Ville Pettilä
BACKGROUND: Data on long-term functional outcome and quality of life (QoL) after out-of-hospital cardiac arrest (OHCA) are limited. We assessed long-term functional outcome and health-related QoL of OHCA survivors regardless of arrest aetiology. METHODS: All adult unconscious OHCA patients treated in 21 Finnish ICUs between March 2010 and February 2011 were followed. Barthel Index (BI), activities of daily living (ADL), accommodation, help needed and received, working status, car driving and self-experienced cognitive deficits were assessed in 1-year survivors (N = 206, 40...
May 15, 2018: Resuscitation
https://www.readbyqxmd.com/read/29775512/improving-post-hospital-medication-management-in-a-danish-municipality-a-process-evaluation
#6
Mette Geil Kollerup, Tine Curtis, Birgitte Schantz Laursen
AIMS AND OBJECTIVES: This study evaluates an intervention developed to improve patient safety in post-hospital medication management carried out by visiting nurses working in a municipality in Denmark. The intervention consisted of three elements: an initial inter-disciplinary home visit by nurses, two subsequent scheduled visits, and the use of an organising tool. BACKGROUND: As a consequence of specialised treatment plans and new treatment possibilities, patients with complex care needs can now be discharged from hospital more rapidly - and in greater numbers - than previously...
May 18, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29775079/improved-glycemic-control-with-minimal-change-in-medication-regimen-complexity-in-a-pharmacist-endocrinologist-diabetes-intense-medical-management-dimm-tune-up-clinic
#7
Candis M Morello, Taylor Rotunno, John Khoan, Jan D Hirsch
BACKGROUND: Gaining glycemic control in patients with type 2 diabetes (T2D) usually requires more complicated medication regimens. Increased medication regimen complexity (MRC) negatively impacts adherence and clinical outcomes. OBJECTIVE: Compare MRC change in patients with uncontrolled T2D referred to a collaborative pharmacist-endocrinologist Diabetes Intense Medical Management (DIMM) clinic "tune up" model versus similar patients receiving usual primary care provider (PCP) care over 6 months...
May 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29774824/technique-of-percutaneous-nephrolithotomy
#8
Ahmed Ibrahim, Daniel Wollin, Glenn Preminger, Sero Andonian
According to the latest American and European Urological Association guidelines, percutaneous nephrolithotomy (PNL) is the current gold standard treatment for patients presenting with symptomatic large or complex renal stones ≥2 cm. This review chapter and accompanying videos will review the latest literature on indications, preoperative preparations, different patient positions, in addition to step by step explanations for the technique of PNL. Postoperative care and troubleshooting tips are provided. Furthermore, latest reported outcomes are reviewed...
May 2018: Journal of Endourology
https://www.readbyqxmd.com/read/29774822/partial-nephrectomy-in-central-renal-tumors
#9
Sohrab Arora, Craig Rogers
Nephron-sparing surgery, especially through a minimally invasive approach, is increasingly being performed for incidentally detected renal masses with excellent outcomes. Tumors in central location remain a surgical challenge during nephron-sparing surgery. In this chapter, we discuss the minimally invasive management of these tumors, which include complex hilar tumors and endophytic central tumors, with a focus on surgical technique. The key to management of these tumors is to maintain good preoperative hydration, achieving adequate exposure of tumor, and the use of intraoperative ultrasound to plan the resection plane...
May 2018: Journal of Endourology
https://www.readbyqxmd.com/read/29774817/bladder-reconstruction-with-bowel-robot-assisted-laparoscopic-ileocystoplasty-with-mitrofanoff-appendicovesicostomy-in-pediatric-patients
#10
Nimrod S Barashi, Maria Veronica Rodriguez, Vignesh T Packiam, Mohan S Gundeti
Neurogenic bladder occur as a consequence of several conditions, most commonly posterior urethral valves syndrome, spina bifida, tethered cord, sacral agenesis, and Arnold-Chiari malformation. It is characterized by diminished bladder capacity and/or reduced compliance, associated with high-pressure voiding that can lead to deterioration of renal function if left untreated. When medical management fails, bladder reconstruction with bowel (aumentation ileocystoplasty) becomes the treatment of choice for these patients...
May 2018: Journal of Endourology
https://www.readbyqxmd.com/read/29774807/robotic-pyelolithotomy-extended-pyelolithotomy-nephrolithotomy-and-anatrophic-nephrolithotomy
#11
Rabii Madi, Ashok Hemal
INTRODUCTION: We are a reporting on the indications, techniques, and limitations of robotic surgery in the management of renal stones disease. Robotic surgery is a good tool to manage large kidney and ureteral stones, particularly in patients with anatomic anomalies. We describe three techniques in managing staghorn kidney stones: robotic anatrophic nephrolithotomy, robotic pyelolithotomy, and robotic nephrolithotomy. MATERIAL AND METHODS: Robotic pyelolithotomy (RP) is ideal for patients with large renal pelvis and partial staghorn stone with a wide extra-renal pelvis...
May 2018: Journal of Endourology
https://www.readbyqxmd.com/read/29774805/men-s-preconception-health-a-primary-health-care-viewpoint
#12
Anthony Paul O'Brien, John Hurley, Paul Linsley, Karen Anne McNeil, Richard Fletcher, John Robert Aitken
The purpose of this article is to theoretically explore men's preconception health as a mechanism to enhance fertility, as well as the health and well-being of the subject and his descendants. Premorbid risk factors and behaviors associated with stress, environmental toxins, excessive alcohol consumption, smoking, lack of exercise/obesity, and the use of illicit drugs are all known to affect fecundity. While there are many health clinics available to women, where advice in areas such as postnatal care of the newborn, family planning, and couples fertility is provided, there are few, if any, equivalent health clinics available to men...
May 1, 2018: American Journal of Men's Health
https://www.readbyqxmd.com/read/29774668/varicocele-and-testicular-pain-a-review
#13
REVIEW
Sunghyun Paick, Woo Suk Choi
Varicocele is the dilatation of the scrotal portion of pampiniform plexus and the internal spermatic venous system. About 15% of men suffer from scrotal varicocele and 2% to 10% of them complain of pain. The probable mechanisms for pain include compression of the surrounding neural fibers by the dilated venous complex, elevated testicular temperature, increased venous pressure, hypoxia, oxidative stress, hormonal imbalances, and the reflux of toxic metabolites of adrenal or renal origin. Testicular pain associated with varicoceles is typically described as a dull, aching, or throbbing pain in the testicle, scrotum, or groin; rarely, it can be acute, sharp, or stabbing...
May 16, 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29774589/healthcare-cost-and-utilization-in-nonalcoholic-fatty-liver-disease-real-world-data-from-a-large-us-claims-database
#14
Alina M Allen, Holly K Van Houten, Lindsey R Sangaralingham, Jayant A Talwalkar, Rozalina G McCoy
The prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing. The health care burden resulting from the multidisciplinary management of this complex disease is unknown. We assessed the total health care cost and resource utilization associated with a new NAFLD diagnosis, compared to controls with similar comorbidities. We used OptumLabs Data Warehouse, a large national administrative claims database with longitudinal health data of over 100 million individuals enrolled in private and Medicare Advantage health plans...
May 18, 2018: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/29774173/role-of-interventional-radiology-in-the-management-of-peripheral-vascular-malformations-a-tertiary-care-center-experience
#15
Misbah Tahir, Muhammad Anees Mumtaz, Anum Sultan, Jawaid Iqbal, Raza Sayani
Peripheral vascular malformations (PVMs) represent a wide spectrum of vascular abnormalities occurring due to anomalous connections between arteries, veins, capillaries, and lymphatic channels at the microscopic level, in different combinations. They are rare and challenging to treat. Different operators may have different approaches based on their experience and expertise. Sclerotherapy either alone or in combination with embolization has been used as an independent method for the treatment of PVMs. Purpose The aim of this study is to assess the safety and efficacy of sclerotherapy and embolization, with or without surgery, for the treatment of peripheral vascular malformations, based on our approach...
March 16, 2018: Curēus
https://www.readbyqxmd.com/read/29774110/high-throughput-3-dimensional-culture-of-epithelial-ovarian-cancer-cells-as-preclinical-model-of-disease
#16
Victoria Heredia-Soto, Andrés Redondo, Alberto Berjón, María Miguel-Martín, Esther Díaz, Roberto Crespo, Alicia Hernández, Laura Yébenes, Alejandro Gallego, Jaime Feliu, David Hardisson, Marta Mendiola
Background: Recent reports have identified distinct genomic patterns in ovarian carcinoma, including proliferative and mesenchymal-like groups, with worse outcome. The exact mechanisms driving the onset and progression of these tumors are still poorly understood. Additionally, researchers are concerned about the correct subtype stratification of the available cell line models, and the exploration of alternatives to monolayer culture. Identification of biomarkers to stratify cell lines, characterization of important processes as epithelial-mesenchymal transition (EMT), and the use of three-dimensional (3D) cultures as alternative models could be useful for cell line classification...
April 24, 2018: Oncotarget
https://www.readbyqxmd.com/read/29773846/appetite-during-the-recovery-phase-of-critical-illness-a-cohort-study
#17
Judith L Merriweather, David M Griffith, Timothy S Walsh
BACKGROUND/OBJECTIVES: Reduced appetite is a recognised physiological symptom in survivors of critical illness. While reduced appetite has been reported by patients after intensive care unit (ICU) discharge, quantification using visual analogue scales (VAS) has not been previously performed, and follow-up duration has been limited. We aimed to describe appetite scores in ICU survivors during the first 3 months after ICU discharge and explore association with systemic inflammation. SUBJECTS/METHODS: Secondary analysis of data collected in a complex rehabilitation intervention trial (RECOVER)...
May 17, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29773446/effects-of-preparatory-coaching-and-home-practice-for-deep-inspiration-breath-hold-on-cardiac-dose-for-left-breast-radiation-therapy
#18
A Kim, A M Kalet, N Cao, D S Hippe, L C Fang, L Young, J Meyer, E V Lang, N A Mayr
AIMS: Deep inspiration breath hold (DIBH) reduces cardiac radiation exposure by creating cardiac-chest wall separation in breast cancer radiotherapy. DIBH requires sustaining chest wall expansion for up to 40 s and involves complex co-ordination of thoraco-abdominal muscles, which may not be intuitive to patients. We investigated the effect of in-advance preparatory DIBH coaching and home practice on cardiac doses. MATERIALS AND METHODS: Successive patients from 1 February 2015 to 31 December 2016 with left-sided breast cancer who underwent tangential field radiotherapy utilising the DIBH technique were included...
May 14, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29773225/-cognitive-decline-in-geriatric-oncology-trends-evaluation-and-treatment
#19
REVIEW
V Antoine, M Courtial, B de Wazieres, A Di Castri, S Duvjnak, L Geronimi, C Labarias, C Le Guillou, A Martin-Allier, D Matelot, C Moitrelle, F Santoni, G Solinas, M Viala
Cancer prevalence increases with aging. Prevalent or incident neurocognitive disorders are frequent in geriatric oncology. Cognitive decline associated with cancer increases the risk of under or over-cancer treatment and makes therapeutic decisions complex. In this context, we present tools to optimize cognitive impairment screening, identification of underlying mechanisms and specific treatments. Geriatric specialists intervention can help global care, social services utilization and patient's orientation when ambulatory cares become difficult...
May 14, 2018: Bulletin du Cancer
https://www.readbyqxmd.com/read/29773072/formal-procedure-to-facilitate-the-decision-to-withhold-or-withdraw-life-sustaining-interventions-in-a-neonatal-intensive-care-unit-a-seven-year-retrospective-study
#20
G Sorin, R Vialet, B Tosello
BACKGROUND: Neonatal deaths are often associated with the complex decision to limit or withdraw life-sustaining interventions (LSIs) rather than therapeutic impasses. Despite the existence of a law, significant disparities in clinical procedures remain. This study aimed to assess deaths occurring in a Neonatal Intensive Care Unit (NICU) and measure the impact of a traceable Limitation or Withdrawal of Active Treatment (LWAT) file on the treatment of these newborns. METHODS: In this monocentric retrospective study, we reviewed all consecutive neonatal deaths occurring during two three-year periods among patients in the NICU at the North Hospital of Marseille: cohort 1 (from 2009 to 2011 without the LWAT file) and cohort 2 (from 2013 to 2015 after introduction of the LWAT file)...
May 17, 2018: BMC Palliative Care
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