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https://www.readbyqxmd.com/read/29140876/evidence-based-guidance-to-assist-volunteers-working-with-at-risk-children-in-a-school-context
#1
Emmy De Buck, Philippe Vandekerckhove, Karin Hannes
AIM: One of the activities of the Belgian Red Cross is the 'Bridging the Gap' project, in collaboration with local schools. In this project, volunteers join the teaching staff to improve personal development goals in at-risk children with poor performance. The aim of this study was to develop evidence-based guidance for the volunteers to help them choose the right didactical approach for supporting these children. METHOD: Systematic literature searches were performed in three bibliographic databases (the Campbell Library, MEDLINE and ERIC) to find the effectiveness of 16 different didactical activities...
November 14, 2017: International Journal of Evidence-based Healthcare
https://www.readbyqxmd.com/read/29135720/clinical-outcome-following-total-joint-replacement-and-arthrodesis-for-hallux-rigidus-a-systematic-review
#2
Jasper Stevens, Robin T A L de Bot, Joris P S Hermus, Lodewijk W van Rhijn, Adhiambo M Witlox
BACKGROUND: Hallux rigidus is a common cause of foot pain in the elderly and has a negative impact on quality of life. Several operative treatment options are available for feet that are refractory to conservative treatment. Of these, total joint replacement and arthrodesis of the first metatarsophalangeal joint are the most commonly performed interventions. Nevertheless, it is still not known which intervention results in the best clinical outcome and the fewest complications. METHODS: PubMed/MEDLINE, Embase, and the Cochrane Library were systematically searched for studies assessing outcome with the American Orthopaedic Foot & Ankle Society-Hallux Metatarsophalangeal Interphalangeal (AOFAS-HMI) score, Foot Function Index (FFI), visual analog scale (VAS) for pain, or Short Form-36 (SF-36) in patients who underwent an arthrodesis or total joint replacement for the treatment of symptomatic hallux rigidus...
November 14, 2017: JBJS Reviews
https://www.readbyqxmd.com/read/29112908/reproductive-decision-making-in-women-living-with-human-immunodeficiency-virus-a-systematic-review
#3
REVIEW
Juan M Leyva-Moral, Patrick A Palmieri, María Feijoo-Cid, Sandra K Cesario, Nataly Julissa Membrillo-Pillpe, Patricia N Piscoya-Angeles, Marilyn Goff, Ana Toledo-Chavarri, Joan E Edwards
OBJECTIVES: Analyze and synthesize the research evidence to understand the reproductive decisions made by women living with HIV from the beginning of the epidemic to the present. Evaluate the barriers and the facilitators for reproductive decision-making. Identify areas of strength, improvement, and those requiring further research. DESIGN AND DATA SOURCES: Systematic review following the PRISMA guideline. PubMed, CINAHL, PsycINFO, Cochrane Library, SocINDEX, Embase, and Scopus databases were searched from 1985 to 2016 using the following Keywords: HIV, AIDS, pregnancy, reproduction, and decision-making...
October 25, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29092948/dcmqi-an-open-source-library-for-standardized-communication-of-quantitative-image-analysis-results-using-dicom
#4
Christian Herz, Jean-Christophe Fillion-Robin, Michael Onken, Jörg Riesmeier, Andras Lasso, Csaba Pinter, Gabor Fichtinger, Steve Pieper, David Clunie, Ron Kikinis, Andriy Fedorov
Quantitative analysis of clinical image data is an active area of research that holds promise for precision medicine, early assessment of treatment response, and objective characterization of the disease. Interoperability, data sharing, and the ability to mine the resulting data are of increasing importance, given the explosive growth in the number of quantitative analysis methods being proposed. The Digital Imaging and Communications in Medicine (DICOM) standard is widely adopted for image and metadata in radiology...
November 1, 2017: Cancer Research
https://www.readbyqxmd.com/read/29061110/a-rapid-and-accurate-approach-for-prediction-of-interactomes-from-co-elution-data-prince
#5
R Greg Stacey, Michael A Skinnider, Nichollas E Scott, Leonard J Foster
BACKGROUND: An organism's protein interactome, or complete network of protein-protein interactions, defines the protein complexes that drive cellular processes. Techniques for studying protein complexes have traditionally applied targeted strategies such as yeast two-hybrid or affinity purification-mass spectrometry to assess protein interactions. However, given the vast number of protein complexes, more scalable methods are necessary to accelerate interaction discovery and to construct whole interactomes...
October 23, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/29052193/identification-of-open-chromatin-regions-in-plant-genomes-using-atac-seq
#6
Marko Bajic, Kelsey A Maher, Roger B Deal
Identifying and characterizing highly accessible chromatin regions assists in determining the location of genomic regulatory elements and understanding transcriptional regulation. In this chapter, we describe an approach to map accessible chromatin features in plants using the Assay for Transposase-Accessible Chromatin, combined with high-throughput sequencing (ATAC-seq), which was originally developed for cultured animal cells. This technique utilizes a hyperactive Tn5 transposase to cause DNA cleavage and simultaneous insertion of sequencing adapters into open chromatin regions of the input nuclei...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29048461/slicemap-an-algorithm-for-automated-brain-region-annotation
#7
M Barbier, A Bottelbergs, R Nuydens, A Ebneth, W H De Vos
Summary: Many neurodegenerative disorders, such as Alzheimer's Disease, pertain to or spread from specific sites of the brain. Hence, accurate disease staging or therapy assessment in transgenic model mice demands automated analysis of selected brain regions. To address this need, we have developed an algorithm, termed SliceMap, that enables contextual quantification by mapping anatomical information onto microtome-cut brain slices. For every newly acquired high-resolution image of a brain slice, the algorithm performs a coarse congealing-based registration to a library of pre-annotated reference slices...
October 18, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29043940/using-maps-to-promote-data-driven-decision-making-one-library-s-experience-in-data-visualization-instruction
#8
Michelle Malizia Catalano, Porcia Vaughn, Joshua Been
Data play a crucial role in health research, education, and patient care. Initiatives such as Big Data to Knowledge (BD2K) and Precision Medicine point to the increasing focus and value of data use and reuse. As the universe of data continues to grow exponentially, health education needs to provide students with practical hands-on learning sessions that illustrate the multitude of uses for data and statistics. Giving students early exposure to data reuse provides a solid background for the more complex data they may gather later in their education...
October 2017: Medical Reference Services Quarterly
https://www.readbyqxmd.com/read/28983198/awareness-adoption-and-application-of-the-association-of-college-research-libraries-acrl-framework-for-information-literacy-in-health-sciences-libraries
#9
Stephanie J Schulte, Maureen Knapp
OBJECTIVE: In early 2016, the Association of College & Research Libraries (ACRL) officially adopted a conceptual Framework for Information Literacy (Framework) that was a significant shift away from the previous standards-based approach. This study sought to determine (1) if health sciences librarians are aware of the recent Framework for Information Literacy; (2) if they have used the Framework to change their instruction or communication with faculty, and if so, what changes have taken place; and (3) if certain librarian characteristics are associated with the likelihood of adopting the Framework...
October 2017: Journal of the Medical Library Association: JMLA
https://www.readbyqxmd.com/read/28968701/interactive-network-visualization-in-jupyter-notebooks-visjs2jupyter
#10
Sara Brin Rosenthal, Julia Len, Mikayla Webster, Aaron Gary, Amanda Birmingham, Kathleen M Fisch
Motivation: Network biology is widely used to elucidate mechanisms of disease and biological processes. The ability to interact with biological networks is important for hypothesis generation and to give researchers an intuitive understanding of the data. We present visJS2jupyter, a tool designed to embed interactive networks in Jupyter notebooks to streamline network analysis and to promote reproducible research. Results: The tool provides functions for performing and visualizing useful network operations in biology, including network overlap, network propagation around a focal set of genes, and co-localization of two sets of seed genes...
September 14, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28968637/dugong-a-docker-image-based-on-ubuntu-linux-focused-on-reproducibility-and-replicability-for-bioinformatics-analyses
#11
Fabiano B Menegidio, Daniela L Jabes, Regina Costa de Oliveira, Luiz R Nunes
Summary: This manuscript introduces and describes Dugong, a Docker image based on Ubuntu 16.04, which automates installation of more than 3500 bioinformatics tools (along with their respective libraries and dependencies), in alternative computational environments. The software operates through a user-friendly XFCE4 graphic interface that allows software management and installation by users not fully familiarized with the Linux command line and provides the Jupyter Notebook to assist in the delivery and exchange of consistent and reproducible protocols and results across laboratories, assisting in the development of open science projects...
September 4, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28944752/a-randomised-controlled-study-of-the-effectiveness-of-breathing-retraining-exercises-taught-by-a-physiotherapist-either-by-instructional-dvd-or-in-face-to-face-sessions-in-the-management-of-asthma-in-adults
#12
Mike Thomas, Anne Bruton, Paul Little, Stephen Holgate, Amanda Lee, Lucy Yardley, Steve George, James Raftery, Jennifer Versnel, David Price, Ian Pavord, Ratko Djukanovic, Michael Moore, Sarah Kirby, Guiqing Yao, Shihua Zhu, Emily Arden-Close, Manimekalai Thiruvothiyur, Frances Webley, Mark Stafford-Watson, Elizabeth Dixon, Lynda Taylor
BACKGROUND: Asthma control is suboptimal, resulting in quality of life (QoL) impairment and costs. Breathing retraining exercises have evidence of effectiveness as adjuvant treatment, but are infrequently used. OBJECTIVES: To transfer the contents of a brief (three-session) physiotherapist-delivered breathing retraining programme to a digital versatile disc (DVD) and booklet format; to compare the effectiveness of the self-guided intervention with that of 'face-to-face' physiotherapy and usual care for QoL and other asthma-related outcomes; to perform a health economic assessment of both interventions; and to perform a process evaluation using quantitative and qualitative methods...
September 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28938982/safe-driving-after-propofol-sedation
#13
Lee Summerlin-Grady, Paul N Austin, Dion A Gabaldon
PURPOSE: Propofol is a short-acting medication with fast cognitive and psychomotor recovery. However, patients are usually instructed not to drive a motor vehicle for 24 hours after receiving propofol. The purpose of this article was to review the evidence examining when it is safe to drive after receiving propofol for sedation for diagnostic and surgical procedures. DESIGN: This is a systematic review of the literature. METHODS: A search of the literature was conducted using Google Scholar, PubMed, and the Cochrane Library for the time period 1990 to 2015...
October 2017: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://www.readbyqxmd.com/read/28938282/efficacy-and-safety-of-tranexamic-acid-in-orthopaedic-fracture-surgery-a-meta-analysis-and-systematic-literature-review
#14
Kamil M Amer, Saqib Rehman, Kamal Amer, Christopher Haydel
BACKGROUND: Tranexamic acid (TXA) is an antifibrinolytic drug that has been shown to be effective in reducing blood loss and the need for transfusions after several orthopaedic surgeries. However, the effectiveness of TXA use in orthopaedic fracture surgeries still remains unclear. The purpose of this meta-analysis was to review existing literature with interest in the effectiveness and safety of TXA treatment in reducing total blood loss and transfusion rates for patients who underwent surgery for fracture repairs...
October 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28927763/imaging-considerations-and-interprofessional-opportunities-in-the-care-of-breast-cancer-patients-in-the-neoadjuvant-setting
#15
REVIEW
Anna G Sorace, Sara Harvey, Anum Syed, Thomas E Yankeelov
OBJECTIVE: To discuss standard-of-care and emerging imaging techniques employed for screening and detection, diagnosis and staging, monitoring response to therapy, and guiding cancer treatments. DATA SOURCES: Published journal articles indexed in the National Library of Medicine database and relevant websites. CONCLUSION: Imaging plays a fundamental role in the care of cancer patients and specifically, breast cancer patients in the neoadjuvant setting, providing an excellent opportunity for interprofessional collaboration between oncologists, researchers, radiologists, and oncology nurses...
November 2017: Seminars in Oncology Nursing
https://www.readbyqxmd.com/read/28925169/-systematic-review-on-safety-of-salvianolate-injection
#16
Zhi-Wei Chen, Yan-Ming Xie, Xing Liao, Gui-Qian Wang
To systematically evaluate the safety of salvianolate injection in clinical medication. A systematic literature search was performed in the databases of Cochrane Library, Medline, Embase, the Web of Science, Clinical Trials, CNKI, VIP, WanFang Data and CBM. Literature screening was done according to inclusion and exclusion criteria, and quality was assessed according to internationally recognized quality evaluation criteria. Then the data were reviewed for analysis. 148 papers were included, consisting of 122 randomized controlled trials(RCTs), 10 non-randomized controlled trials(NRCTs), 4 case series studies, and 12 case reports...
October 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28915003/the-evolution-of-dna-templated-synthesis-as-a-tool-for-materials-discovery
#17
Rachel K O'Reilly, Andrew J Turberfield, Thomas R Wilks
Precise control over reactivity and molecular structure is a fundamental goal of the chemical sciences. Billions of years of evolution by natural selection have resulted in chemical systems capable of information storage, self-replication, catalysis, capture and production of light, and even cognition. In all these cases, control over molecular structure is required to achieve a particular function: without structural control, function may be impaired, unpredictable, or impossible. The search for molecules with a desired function is often achieved by synthesizing a combinatorial library, which contains many or all possible combinations of a set of chemical building blocks (BBs), and then screening this library to identify "successful" structures...
October 17, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28884849/anger-parameters-in-parolees-undergoing-psychoeducation-temporal-stability-social-desirability-bias-and-comparison-with-non-offenders
#18
Ephrem Fernandez, Vasiliki Kiageri, Deepan Guharajan, Andrew Day
BACKGROUND: Anger is commonly measured as if it were a single, simple construct. This may be particularly unhelpful if the main purpose of a measure is to determine change and responsiveness to interventions. AIMS: Our primary aim was to assess five anger parameters in parolees - frequency, duration, intensity, latency, and threshold - and to test for effects of psychoeducation and social desirability bias on parolees' scores. Average anger scores for the offender sample were compared with those in a non-offender sample...
September 8, 2017: Criminal Behaviour and Mental Health: CBMH
https://www.readbyqxmd.com/read/28880347/-using-resource-groups-in-assertive-community-treatment-literature-review-and-recommendation
#19
M Smeerdijk, P H A E G Delespaul, I P M Keet, M A Nugter
In psychiatry there is an increasing interest in giving patients and their relatives control over the goals of treatment and the way in which treatment is carried out. A structural method of organising this within assertive community treatment (ACT) is to let patients and their relatives participate in what is known as a resource group (RG).<br/> AIM: To provide a systematic view of the advantages of giving patients control over their treatment and the way in which it is carried out via ACT, particularly if this control is organised in the form of an RG...
2017: Tijdschrift Voor Psychiatrie
https://www.readbyqxmd.com/read/28809177/health-sciences-library-closings-a-context-sensitive-pilot-study
#20
Diane G Schwartz, Peter L Elkin
A significant number of U.S. health sciences libraries have closed since the mid-1990's. A pilot study was conducted with academic physicians to understand the impact of closing the health sciences library in the teaching hospital with which they were affiliated. A brief survey was designed and distributed to fourteen faculty members with thirteen useable responses received. The study elicited a context-sensitive perspective on the closing of the library with the most noteworthy outcome being the additional time required by attending physicians and trainees to perform the work that previously was performed by library staff...
2017: Studies in Health Technology and Informatics
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