Kaori Takahashi, Hiroshi Nango, Mitsuyasu Ushijima, Miyuki Takashima, Masato Nakamoto, Toshiaki Matsutomo, Hiroshi Jikihara, Nanami Arakawa, Shinichiro Maki, Akira Yabuki, Yasuyuki Endo, Osamu Yamato
Periodontal disease is one of the most common dental health problems in dogs. Clinical studies in humans have shown that aged garlic extract (AGE), which contains stable and water-soluble sulfur-containing bioactive compounds, improves the symptoms of periodontal diseases. Our previous study demonstrated that oral administration of AGE in healthy Beagle dogs at 90 mg/kg/day for 12 weeks had no adverse effects such as hemolytic anemia, which is well known to occur as a result of ingestion of Allium species, including onions and garlic, in dogs...
2023: Frontiers in Veterinary Science