keyword
https://read.qxmd.com/read/38406046/a-case-of-bullous-sweet-s-syndrome-associated-with-esophageal-adenocarcinoma
#1
Adriana G Bagos-Estevez, Sarah Moore, Leslie Turner, Brooke Baldwin
Sweet's syndrome (SS), or acute febrile neutrophilic dermatosis, characteristically presents with fever, dermal neutrophilic infiltrates, and neutrophilia. It typically manifests as tender erythematous plaques; however, various variants are documented, including bullous. Malignancy-associated Sweet's syndrome (MASS) can present as a paraneoplastic syndrome in those with established cancers or with undiagnosed malignancies. We present a 72-year-old male with a three-day history of a progressive bullous, erythematous papular rash starting on his right forearm and spreading to his extremities, trunk, palms, and soles...
January 2024: Curēus
https://read.qxmd.com/read/38378483/earthquake-victims-in-focus-a-cross-sectional-examination-of-trauma-and-management-in-intensive-care-unit
#2
JOURNAL ARTICLE
Kaniye Aydin, Aysun Ozel Yesilyurt, Ferhat Cetinkaya, Mehmet Gokhan Gok, Omer Dogan, Dilek Ozcengiz
BACKGROUND: After the Kahramanmaras earthquake of February 6, 2023, the disaster of the century, a significant number of victims were admitted to intensive care units (ICUs). In this study, we aimed to share the characteristics and management of critical earthquake victims and shed light on our experiences as intensivists in future earthquakes. METHODS: The study included 62 earthquake victims in two tertiary ICUs. Demographic characteristics, laboratory findings, clinical characteristics, trauma and disease severity scores, treatments administered to patients, and the clinical course of the patients were recorded retrospectively...
February 20, 2024: BMC Emergency Medicine
https://read.qxmd.com/read/38222004/predictive-value-of-hajibandeh-index-in-determining-peritoneal-contamination-in-acute-abdomen-a-cohort-study-and-meta-analysis
#3
JOURNAL ARTICLE
Shahab Hajibandeh, Shahin Hajibandeh, Louis Evans, Bethany Miller, Jennifer Waterman, Suhaib Js Ahmad, Jay Hale, Adnan Higgi, Bethan Johnson, Dafydd Pearce, Ahmed Hazem Helmy, Nader Naguib, Andrew Maw
BACKGROUND: Hajibandeh index (HI), derived from combined levels of C-reactive protein, lactate, neutrophils, lymphocytes and albumin, is a modern predictor of peritoneal contamination and mortality in patients with acute abdominal pathology. AIM: To validate the performance of HI in predicting the presence and nature of peritoneal contamination in patients with acute abdominal pathology in a larger cohort study and to synthesis evidence in a systematic review and meta-analysis...
December 27, 2023: World Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/38094900/visible-negative-pressure-wound-therapy-for-open-abdominal-management-a-single-center-retrospective-study
#4
JOURNAL ARTICLE
Jumpei Takamatsu, Yuichi Yasue, Aya Fukuhara, Jinkoo Kang, Masatoshi Nakata, Hajime Nakajima, Jun Oda
AIM: This study aimed to compare open abdominal management (OAM) between visible negative pressure wound therapy (NPWT) and commercial NPWT to determine whether NPWT can detect intestinal ischemia in its early stages without causing complications or worsening prognosis, and to determine whether the actual visualization results in early detection. METHODS: Patients were divided into two groups: those who underwent OAM with visible NPWT (A: 32 patients) and those who underwent OAM with commercial NPWT (B: 12 patients)...
2023: Acute Medicine & Surgery
https://read.qxmd.com/read/37171317/acute-mesenteric-ischemia-diagnosed-using-the-aquarium-sign-a-case-report
#5
JOURNAL ARTICLE
Ushio Higashijima, Motohiro Sekino, Naoya Iwasaki, Hiroshi Araki, Tetsufumi Motokawa, Yusuke Inoue, Yasuhiro Taniguchi, Shinya Sato, Yasushi Miyazaki, Tetsuya Hara
RATIONALE: The diagnosis of mesenteric ischemia in critically ill patients remains challenging; however, the aquarium sign, comprising a large number of bubble images in the right cardiac chambers on echocardiography, may be used as a point-of-care ultrasound finding to diagnose acute mesenteric ischemia (AMI). PATIENT CONCERNS: A 65-year-old woman diagnosed with lymphoma was urgently admitted to the intensive care unit with suspected tumor lysis syndrome. High-dose vasopressor and inotropic agents were required to manage the patient's shock with marked lactic acidosis and peripheral hypoperfusion with mottled skin, and multidisciplinary treatment was initiated...
May 12, 2023: Medicine (Baltimore)
https://read.qxmd.com/read/36686342/management-of-infected-acute-necrotizing-pancreatitis
#6
JOURNAL ARTICLE
Efstathios T Pavlidis, Theodoros E Pavlidis
Necrotizing or severe pancreatitis represents approximately 10%-20% of acute pancreatitis. 30%-40% of patients with acute necrotizing pancreatitis (ANP) will develop debris infection through translocation of intestinal microbial flora. Infected ANP constitutes a serious clinical condition and is complicated by severe sepsis with high mortality rates of up to 40% despite progress in current intensive care. The timely detection of sepsis is crucial. The Quick Sequential Organ Failure Assessment score, procalcitonin levels > 1...
January 16, 2023: World Journal of Clinical Cases
https://read.qxmd.com/read/35089964/intravenous-ringers-lactate-versus-normal-saline-for-predominantly-mild-acute-pancreatitis-in-a-nepalese-tertiary-hospital
#7
JOURNAL ARTICLE
Binod Karki, Suresh Thapa, Dibas Khadka, Sanjit Karki, Roshan Shrestha, Ajit Khanal, Ramila Shrestha, Bidhan Nidhi Paudel
BACKGROUND: Acute pancreatitis (AP) is a common presentation in patients admitted with acute abdomen. Whether Ringers lactate (RL) or Normal Saline (NS) as a resuscitation fluid is better still remains unclear. The aim of this study is to compare the efficacy of RL and NS in terms of control of systemic inflammation by measuring indirect markers specifically Systemic Inflammation Response Syndrome (SIRS) scores and C- Reactive Protein (CRP) level. METHODS: This was an open label randomized trial conducted in a tertiary level hospital of Nepal...
2022: PloS One
https://read.qxmd.com/read/35044063/interpreting-abdominal-fluid-in-colic-horses-understanding-and-applying-peritoneal-fluid-evidence
#8
JOURNAL ARTICLE
Rolfe M Radcliffe, Sharon Y Liu, Vanessa L Cook, Samuel D A Hurcombe, Thomas J Divers
BACKGROUND: Interpreting changes in peritoneal fluid helps clinicians manage colic and other diseases in horses. During abdominal problems in the horse, abdominal fluid characteristics such as color, turbidity, total nucleated and red blood cell counts, cytology, total protein, and l-lactate change in predictable ways, helping the clinician characterize the disease. DESCRIPTION: Normal abdominal fluid in horses is odorless, clear to light yellow in color, and transparent...
January 2022: Journal of Veterinary Emergency and Critical Care
https://read.qxmd.com/read/34967103/significance-of-laboratory-parameters-in-diagnosing-acute-appendicitis-during-pregnancy
#9
JOURNAL ARTICLE
Rıfat Peksöz, Esra Dişçi, Abdulkadir Kaya, Enes Ağırman, Ercan Korkut, Nurhak Aksungur, Necip Altundaş, Salih Kara, Sabri Selçuk Atamanalp
BACKGROUND: Acute appendicitis (AA) is the most frequently seen surgical emergency in pregnant women and the most frequently encountered cause of non-obstetric acute abdomen. Due to the physiological and anatomical changes that occur during pregnancy and the limited use of radiological methods, it is difficult to diagnose AA during pregnancy. These conditions increase the risk of morbidity and mortality; therefore, it is crucial to identify ideal laboratory markers that can be utilized to diagnose disease...
January 2022: ANZ Journal of Surgery
https://read.qxmd.com/read/34711792/gastroesophageal-resuscitative-occlusion-of-the-aorta-prolongs-survival-in-a-lethal-liver-laceration-model
#10
JOURNAL ARTICLE
Brendan M McCracken, Mohamad Hakam Tiba, Carmen I Colmenero, Danielle C Leander, Nicholas L Greer, Jeffery S Plott, Albert J Shih, Stewart C Wang, Jonathan L Eliason, Kevin R Ward
BACKGROUND: Non-compressible torso hemorrhage management remains a challenge especially in the prehospital setting. We evaluated a device designed to occlude the aorta from the stomach (Gastroesophageal Resuscitative Occlusion of the Aorta (GROA)) for its ability to stop hemorrhage and improve survival in a swine model of lethal liver laceration and compared its performance to Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) and controls. METHODS: Swine (n = 24) were surgically instrumented and a 30% controlled arterial hemorrhage over 20-minutes was followed by liver laceration...
October 27, 2021: Journal of Trauma and Acute Care Surgery
https://read.qxmd.com/read/33867519/lifestyle-changes-normalize-serum-lactate-levels-in-an-m-3243a-g-carrier
#11
JOURNAL ARTICLE
Josef Finsterer
BACKGROUND The normalization of serum lactate levels in a patient with non-syndromic mitochondrial disorder due to the m.3243A>G mitochondrial DNA (mtDNA) variant has not been previously reported. CASE REPORT A 57-year-old woman was diagnosed with mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) due to the m.3243A>G variant, with low heteroplasmy rates (31%), at age 50. The initial manifestations were short stature, migraine, and diabetes. With progression of the disease, multisystem involvement developed, affecting the brain (stroke-like episode, mild cognitive impairment), eyes (pigmentary retinopathy), ears and the vestibular system (impaired hearing, tinnitus, imbalance, drop attacks, vertigo), intestines (constipation, distended abdomen, gastro-esophageal reflux, gastroparesis), and the muscles (muscle weakness)...
April 19, 2021: American Journal of Case Reports
https://read.qxmd.com/read/33727772/abdominal-paracentesis-drainage-attenuates-intestinal-inflammation-in-rats-with-severe-acute-pancreatitis-by-inhibiting-the-hmgb1-mediated-tlr4-signaling-pathway
#12
JOURNAL ARTICLE
Shang-Qing Huang, Yi Wen, Hong-Yu Sun, Jie Deng, Yao-Lei Zhang, Qi-Lin Huang, Bing Wang, Zhu-Lin Luo, Li-Jun Tang
BACKGROUND: Our previous studies confirmed that abdominal paracentesis drainage (APD) attenuates intestinal mucosal injury in rats with severe acute pancreatitis (SAP), and improves administration of enteral nutrition in patients with acute pancreatitis (AP). However, the underlying mechanisms of the beneficial effects of APD remain poorly understood. AIM: To evaluate the effect of APD on intestinal inflammation and accompanying apoptosis induced by SAP in rats, and its potential mechanisms...
March 7, 2021: World Journal of Gastroenterology: WJG
https://read.qxmd.com/read/33503619/acute-mesenteric-infarction-the-chameleon-of-acute-abdomen-evaluating-the-quality-of-the-diagnostic-parameters-in-acute-mesenteric-ischemia
#13
JOURNAL ARTICLE
Rainer Grotelueschen, Verena Miller, Lena M Heidelmann, Nathaniel Melling, Tarik Ghadban, Katharina Grupp, Matthias Reeh, Maria-Noemi Welte, Faik Güntac Uzunoglu, Jakob R Izbicki, Kai A Bachmann
INTRODUCTION/OBJECTIVE: Acute mesenteric ischemia (AMI) is difficult to diagnose. Since the established parameters have low sensitivity and specificity, the aim of this study is to analyze the diagnostic quality of the established parameters of AMI. METHODS: All patients that underwent emergency surgery due to suspected diagnosis of mesenteric ischemia at the University Medical Center Hamburg-Eppendorf between 2008 and 2014 were evaluated. Overall, 275 patients were enrolled and pre-, intra- and postoperative data were evaluated...
2021: Digestive Surgery
https://read.qxmd.com/read/33356444/hospital-presentations-of-acute-diverticulitis-during-covid-19-pandemic-may-be-more-likely-to-require-surgery-due-to-increased-severity-a-single-centre-experience
#14
JOURNAL ARTICLE
Naveed Hossain, Vishnu Naidu, Shady Hosny, Mohamed Khalifa, Pawan Mathur, Maitham Al Whouhayb
BACKGROUND: The novel coronavirus disease 2019 (COVID-19) pandemic has resulted in fewer emergency presentations of many acute medical and surgical conditions. The purpose of this study was to assess the severity of disease at presentation and quantify the change in number of presentations during this period. METHODS: This retrospective study includes all patients diagnosed with acute diverticulitis on abdominopelvic computerised tomography (CT) between March 1, 2020 and June 30, 2020, compared to the same period in 2019...
January 2022: American Surgeon
https://read.qxmd.com/read/32890337/colorectal-resection-in-emergency-general-surgery-an-east-multicenter-trial
#15
MULTICENTER STUDY
Brittany O Aicher, Matthew C Hernandez, Alejandro Betancourt-Ramirez, Michael D Grossman, Holly Heise, Thomas J Schroeppel, Napaporn Kongkaewpaisan, Haytham M A Kaafarani, Afton Wagner, Daniel Grabo, Michael Scott, Gregory Peck, Gloria Chang, Kazuhide Matsushima, Daniel C Cullinane, Laura M Cullinane, Benjamin Stocker, Joseph Posluszny, Ursula J Simonoski, Richard D Catalano, Georgia Vasileiou, D Dante Yeh, Vaidehi Agrawal, Michael S Truitt, MaryAnne Pickett, Linda Dultz, Alison Muller, Adrian W Ong, Janika L San Roman, Nadine Barth, Oliver Fackelmayer, Catherine G Velopulos, Cheralyn Hendrix, Jordan M Estroff, Sahil Gambhir, Jeffry Nahmias, Kokila Jeyamurugan, Nikolay Bugaev, Victor Portillo, Matthew M Carrick, Lindsay O'Meara, Joseph Kufera, Martin D Zielinski, Brandon R Bruns
OBJECTIVE: Evidence comparing stoma creation (STM) versus anastomosis after urgent or emergent colorectal resection is limited. This study examined outcomes after colorectal resection in emergency general surgery patients. METHODS: This was an Eastern Association for the Surgery of Trauma-sponsored prospective observational multicenter study of patients undergoing urgent/emergent colorectal resection. Twenty-one centers enrolled patients for 11 months. Preoperative, intraoperative, and postoperative variables were recorded...
December 2020: Journal of Trauma and Acute Care Surgery
https://read.qxmd.com/read/32699722/metformin-associated-lactic-acidosis-in-the-intensive-care-unit-a-rare-condition-mimicking-sepsis
#16
Selin Sendil, Keerthi Yarlagadda, Halimat Lawal, Vinod Nookala, Hiren Shingala
Metformin-associated lactic acidosis (MALA) is a rare but serious complication of metformin use, associated with high mortality. MALA can occur any time a patient on metformin suffers disruption in renal function resulting in the accumulation of metformin. A 63-year-old man with a history of non-insulin-dependent type 2 diabetes mellitus, alcohol abuse, and hypothyroidism was brought to the emergency department with altered mental status, nausea, vomiting, and abdominal pain. He was found to be in respiratory distress, was hypotensive and hypoglycemic (48 mg/dL), and required emergent intubation...
July 10, 2020: Curēus
https://read.qxmd.com/read/32275007/-protective-effect-and-mechanism-of-ribociclib-on-sepsis-induced-acute-kidney-injury
#17
JOURNAL ARTICLE
Qian Wang, Xiaoying Gong, Jia Jia, Guofu Li
OBJECTIVE: To investigate the role of Ribociclib in sepsis induced-acute kidney injury (AKI) and its possible mechanisms. METHODS: (1) Twenty adult male C57BL/6 mice were divided into sham operation group (Sham group; only open the abdomen without ligating or perforating the cecum, administered with sodium lactate buffer 12 hours before the sham operation), Ribociclib control group (administered with 150 mg/kg Ribociclib), cecal ligation and puncture (CLP) group (sepsis model induced by CLP; lactate buffer was given by intragastric administration 12 hours before CLP), and Ribociclib pretreatment group (administered with 150 mg/kg Ribociclib 12 hours before CLP) according to random number table, with 5 mice in each group...
February 2020: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://read.qxmd.com/read/31955259/intra-abdominal-pressure-may-be-elevated-in-patients-with-open-abdomen-after-emergent-laparotomy
#18
JOURNAL ARTICLE
Ohad Guetta, Evgeni Brotfain, Gad Shaked, Gilbert Sebbag, Moti Klein, David Czeiger
PURPOSE: To estimate the change in intra-abdominal pressure (IAP) among critically ill patient who were left with open abdomen and temporary abdominal closure after laparotomy, during the first 48 h after admission. METHODS: A cohort study in a single ICU in a tertiary care hospital. All adult patients admitted to the ICU after emergent laparotomy for acute abdomen or trauma, who were left with temporary abdominal closure (TAC), were included. Patients were followed up to 48 h...
February 2020: Langenbeck's Archives of Surgery
https://read.qxmd.com/read/31440795/patient-s-characteristics-and-outcomes-in-necrotising-soft-tissue-infections-results-from-a-scandinavian-multicentre-prospective-cohort-study
#19
MULTICENTER STUDY
Martin Bruun Madsen, Steinar Skrede, Anders Perner, Per Arnell, Michael Nekludov, Trond Bruun, Ylva Karlsson, Marco Bo Hansen, Peter Polzik, Morten Hedetoft, Anders Rosén, Edoardo Saccenti, François Bergey, Vitor A P Martins Dos Santos, Anna Norrby-Teglund, Ole Hyldegaard
PURPOSE: Necrotising soft-tissue infections (NSTI) are characterised by necrosis, fast progression, and high rates of morbidity and mortality, but our knowledge is primarily derived from small prospective studies and retrospective studies. METHODS: We performed an international, multicentre, prospective cohort study of adults with NSTI describing patient's characteristics and associations between baseline variables and microbiological findings, amputation, and 90-day mortality...
September 2019: Intensive Care Medicine
https://read.qxmd.com/read/31240505/utility-of-biphasic-multi-detector-computed-tomography-in-suspected-acute-mesenteric-ischemia-in-the-emergency-department
#20
JOURNAL ARTICLE
Prasaanthan Gopee-Ramanan, Michael N Patlas, Bharadwaj Pindiprolu, Douglas S Katz
PURPOSE: To retrospectively evaluate the utility of biphasic multi-detector computed tomography (MDCT) with arterial and portal venous phases for the detection of suspected acute mesenteric ischemia (AMI) in emergency department (ED) patients compared to limited surgical confirmation. METHODS: A research ethics board (REB)-approved retrospective review of all consecutive adult patients who underwent an emergency biphasic 64-MDCT examination of the abdomen and pelvis due to clinical suspicion for AMI over a 5-year period at a single tertiary-care institution was performed...
October 2019: Emergency Radiology
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