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acute abdomen and lactate level

B Aydin, M Ozban, M Serinken, B Kaptanoglu, N C Demirkan, C Aydin
INTRODUCTION: Acute mesenteric ischemia (AMI) is an abdominal-vascular emergency which is rare and has high mortality rates (60-80 %) due to late diagnosis (1-3). Although it is known that extravascular reasons like intestinal intussusception, volvulus, strangulated hernias and obstructions can cause intestinal gangrene, these are rarely the cause of AMI (1). MATERIALS AND METHODS: In this study, we used male Wistar-Albino rats weighing 250-300 grams obtained from Pamukkale University Experimental Research Laboratory...
2015: Bratislavské Lekárske Listy
Fazıl Sağlam, Emre Sivrikoz, Ali Alemdar, Sedat Kamalı, Ufuk Arslan, Hakan Güven
The patient presented in this study was a 54-year-old woman complaining of nausea and vomiting, onset preceding four days, with no significant past medical history and an unremarkable surgical history. The patient was afebrile and hypertensive. Physical examination revealed a non-tender abdomen, and initial laboratory evaluation revealed elevated blood glucose level, ketonuria, leukocytosis, elevated C-reactive protein, gamma glutamyl transferase, lactate dehydrogenase, and total bilirubin. The patient was admitted to the internal medicine ward due to new onset of diabetes mellitus...
March 2015: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
Andrew Goldberg
A 52-year-old man presented with acute, sharp chest pain radiating to the back and abdomen after using cocaine 18 hours previously. Computed tomographic angiography revealed a type B aortic dissection that extended to the iliac arteries. The patient underwent balloon fenestration, placement of multiple aortic stents, and bilateral leg fasciotomy. He eventually went into hyperkalemic arrest but was successfully resuscitated, after which his serum lactate and creatine kinase levels peaked at 7.4 mmol/L and 990,400 U/L, respectively...
March 15, 2015: A & A Case Reports
Hui Shi, Benyan Wu, Jun Wan, Wenhui Liu, Binbin Su
BACKGROUND AND OBJECTIVE: To evaluate the clinical usefulness of serum intestinal fatty acid binding protein (I-FABP) and D-lactate measurements in the early diagnosis of acute intestinal ischemia. METHODS: A total of 272 patients with a clinical diagnosis of acute abdomen were recruited for this trial over a 24-month period, and 37 healthy people were included in the study as controls. Serum I-FABP and D-lactate levels were measured by an enzyme-linked immunosorbent assay and compared in patients with intestinal ischemia vs...
June 2015: Clinics and Research in Hepatology and Gastroenterology
Indu Verma, Satinder Kaur, Subash Goyal, Shweta Goyal, J S Multani, A P S Narang
The supply of oxygen is limited in certain intra abdominal conditions due to direct vascular invasion or inflammatory process, resulting in high lactate levels. Aim of this study was to find the predictive value of lactate levels in the peritoneal fluid (PF) and blood of patients with acute abdomen. The study comprised of fifty patients with acute abdominal conditions, admitted in emergency ward of tertiary care hospital, thirty patients were with surgical abdomen (group I) and twenty patients with non surgical abdomen (group II)...
July 2014: Indian Journal of Clinical Biochemistry: IJCB
Cecilia Ceribelli, Ennio Alberto Adami, Simona Mattia, Bruno Benini
BACKGROUND: Bedside diagnostic laparoscopy has an important role of diagnosing acute abdomen in critically ill patients hospitalized in the intensive care unit (ICU). Delayed diagnosis of intraabdominal pathology increases the morbidity and mortality rates for these patients, whose clinical signs often are absent due to analgesic medication and sedation. METHODS: In this retrospective study performed from January 2007 to December 2009, 62 consecutive ICU patients whose blood test results showed them to be hemodynamically unstable underwent bedside diagnostic laparoscopy...
December 2012: Surgical Endoscopy
Ashvin K Tadakamalla, Siva K Talluri, Siddesh Besur
CONTEXT: Schistocytes are fragmented red blood cells due to the flow of blood through damaged capillaries and indicate endothelial injury. They are typical of microangiopathic hemolytic anemia seen in life threatening conditions like disseminated intravascular coagulation or thrombotic thrombocytopenic purpura/hemolytic uremic syndrome .We report a rare sub-acute presentation of pernicious anemia with hemolysis, thrombocytopenia and numerous schistocytes that was initially diagnosed as a more serious thrombotic thrombocytopenic purpura...
October 2011: North American Journal of Medical Sciences
Marleen S van Brussel, Cornelis T Grutters, Cornelis A Verburgh
BACKGROUND: Renal infarction is a condition not known to every physician, with often non-specific symptoms. The diagnosis is therefore often not considered initially in patients with acute abdominal pain. CASE DESCRIPTIONS: In a 77-year-old man a renal infarction was found by chance on a CT-scan performed performed for the evaluation of dyspnoea. Previously he had visited the emergency unit with abdominal pain, in retrospect attributable to renal infarction. A 61-year-old man initially labelled as suffering from gastro-enteritis was diagnosed correctly with renal infarction after his renal function deteriorated and the lactate dehydrogenase (LDH) activity increased...
2011: Nederlands Tijdschrift Voor Geneeskunde
Stefan Acosta, Torbjörn Nilsson
Clinical diagnosis of acute mesenteric ischemia is difficult. The aim of this review is to provide current status on the search for an accurate plasma biomarker for acute mesenteric ischemia. A search using the medical subject heading terms marker and mesenteric ischemia or intestinal ischemia or superior mesenteric artery occlusion or mesenteric venous thrombosis in the Medline and Embase databases from 1980 to 2011. Studies without a control group or a control group consisted of healthy individuals (human studies), or studies on intestinal reperfusion were excluded...
May 2012: Journal of Thrombosis and Thrombolysis
Praveen Ravishankaran, Ashwini M Shah, Ravindra Bhat
In the present scenario, doctors have to rely on radiological methods for diagnosis of acute abdomen in addition to their clinical skill. The use of serum markers for assessing the outcome of such patients is still debatable. Our aim was to evaluate whether the combined use of serum lactate, interleukin (IL)-6, and C-reactive protein (CRP) is able to simultaneously establish both the septic status and the prognosis of acute abdomen. Ninety-nine patients undergoing surgery for acute abdomen were taken up for the study...
September 2011: Journal of Interferon & Cytokine Research
Ming-Yuan Hong, Chih-Hsien Chi
A 67-year-old man presented to the emergency department with acute abdominal pain, which had started 3 hours earlier. On physical examination, the abdomen was distended and tender to palpation. The levels of serum lipase and lactate were within normal limits, as were the white-cell count and..
July 28, 2011: New England Journal of Medicine
Tatsuo Kanda, Akihiro Tsukahara, Kyo Ueki, Yasuo Sakai, Tatsuo Tani, Atsushi Nishimura, Toshiyuki Yamazaki, Yoichi Tamiya, Tetsuya Tada, Masaki Hirota, Jun Hasegawa, Hiroyuki Funaoka, Hiroshi Fujii, Katsuyoshi Hatakeyama
BACKGROUND: Intestinal fatty acid-binding protein (I-FABP) is a low-molecular-mass (15 kDa) cytosolic protein found exclusively in the epithelial cells of the small bowel mucosa. We aimed to evaluate the clinical usefulness of serum I-FABP measurement for the diagnosis of ischemic small bowel disease. METHODS: Patients with a clinical diagnosis of acute abdomen were recruited for this multicenter trial at one university hospital and nine city hospitals over a 13-month period...
April 2011: Journal of Gastroenterology
Ali Ilker Filiz, Hakan Aladag, Mehmet Levhi Akin, Ilker Sucullu, Yavuz Kurt, Ergun Yucel, Ahmet Haldun Uluutku
INTRODUCTION: Early diagnosis of acute appendicitis, known as the most frequent cause of acute surgical abdominal pathologies, dramatically decreases the related complications. D-lactate, produced by intestinal bacteria as a fermentation product, may be useful in diagnosing acute abdominal pathologies. The aim of this study was to investigate whether the presence of d-lactate would be a significant indicator in the early diagnosis of acute appendicitis. METHODS: Eighty consecutive patients were prospectively included in this study...
August 2010: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
Sheng-Hua Li, Fen Liu, Ying-Tian Zhang
OBJECTIVE: To evaluate the value of immediate postoperative arterial lactate level to predict morbidity after major abdominal surgery. METHODS: 139 patients, 73 males and 66 females, aged (64 +/- 14) (26 - 87), who underwent major abdominal surgery had their levels of arterial lactate, blood routine, blood gas and electrolytes measured after they were sent to the ICU. The physiological and operative severity score for the enumeration of mortality and morbidity (POSSUM) and the simplified acute physiology score II (SAPSII) levels in the first 24-hour postoperative period were calculated Multivariate logistic regression analysis was utilized to examine the independent relationship of the initial lactate, blood gas values, and anion gap with the morbidity...
September 16, 2008: Zhonghua Yi Xue za Zhi [Chinese medical journal]
C Delesalle, J Dewulf, R A Lefebvre, J A J Schuurkes, B Van Vlierbergen, P Deprez
OBJECTIVE: Hypocalcaemia is a common finding in horses with enterocolitis and severe gastrointestinal disorders. The aims of this study were to investigate in colic horses 1)the parameters related to hypocalcaemia, 2)the influence of hypocalcaemia on outcome and 3)the possible beneficial effect of Ca2+ substitution. DESIGN: Randomized controlled trial. SETTING: Intensive care unit. PATIENTS: One hundred forty-four horses that were admitted with an acute abdomen during a 1...
December 2005: Veterinary Quarterly
S Yol, E B Bostanci, Y Ozogul, N I Zengin, U Ozel, A Bilgihan, M Akoglu
BACKGROUND: In the management of mild acute biliary pancreatitis, it is generally recommended to perform laparoscopic cholecystectomy after the subsidence of the attack during the same hospital admission. The effect of laparoscopy on abdominal organs has been widely investigated but not in acute pancreatitis. This study used an animal model of mild acute pancreatitis to examine the effects of CO(2) pneumoperitoneum on acute pancreatitis in rats. METHODS: Mild acute pancreatitis was induced in 30 male Sprague-Dawley rats by surgical ligation of the biliopancreatic duct...
December 2004: Surgical Endoscopy
Tetsuro Yoshida, Noriyuki Ikehara, Hiromichi Miyabe, Seiichiro Sakata, Kazuhiro Yajima, Seiji Mukai, Nobuyuki Ohte, Genjiro Kimura
We experienced two cases of renal infarction with atrial fibrillation who presented with acute abdominal pain. On initial urinalysis, both patients showed no hematuria, but the plasma lactate dehydrogenase level was markedly elevated with little or no rise in plasma transaminases. Their diagnosis was confirmed by contrast-enhanced CT of the abdomen on the second and third days of the crisis. We immediately initiated anticoagulant therapy, resulting in successful prevention of new embolism. Contrast-enhanced CT should be considered if abdominal symptoms develop in patients with atrial fibrillation...
July 2004: Hypertension Research: Official Journal of the Japanese Society of Hypertension
Julia A Johnson, Jeanine B Albu, Ellen S Engelson, Susan K Fried, Yoritaro Inada, Gabriel Ionescu, Donald P Kotler
The lipodystrophy syndrome (adipose tissue redistribution and metabolic abnormalities) observed with highly active antiretroviral therapy (HAART) during human immunodeficiency virus (HIV) infection may be related to increased proinflammatory cytokine activity. We measured acute cytokine (TNF-alpha, IL-6, leptin), glycerol, and lactate secretion from abdominal subcutaneous adipose tissue (SAT), and systemic cytokine levels, in HIV-infected subjects with and without lipodystrophy (HIVL+ and HIVL-, respectively) and healthy non-HIV controls...
February 2004: American Journal of Physiology. Endocrinology and Metabolism
T Hackert, P Kienle, J Weitz, J Werner, G Szabo, S Hagl, M W Büchler, J Schmidt
BACKGROUND: In the early postoperative period after major cardiac surgery using extracorporal circulation, abdominal complications can have serious consequences with a mortality rate of up to 70%. Early diagnosis and the timely institution of therapy are the most important factors to improve the outcome; however, clinical evaluation of the abdomen is difficult in these patients. Diagnostic laparoscopy is a minimally invasive procedure with low procedure-associated morbidity, even in critically ill patients...
October 2003: Surgical Endoscopy
Ze'ev Korzets, Eleanora Plotkin, Jacques Bernheim, Rivka Zissin
BACKGROUND: Acute renal infarction is an oft-missed diagnosis. As a result, its true incidence, although presumed to be low, is actually unknown. Surprisingly, the medical literature on the subject, other than anecdotal case reports, is scarce. OBJECTIVES: To increase physician awareness of the diagnosis and to identify predictive clinical and laboratory features of the entity. METHOD: Between 1 November 1997 and 31 October 2000, 11 cases of acute renal infarction in 10 patients were diagnosed in our center by contrast-enhanced computerized tomography...
October 2002: Israel Medical Association Journal: IMAJ
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