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https://www.readbyqxmd.com/read/29159847/more-or-less-likely-to-offend-young-adults-with-a-history-of-identified-developmental-language-disorders
#1
Maxine Winstanley, Roger T Webb, Gina Conti-Ramsden
BACKGROUND: There is now substantial literature demonstrating that a disproportionate number of young people who come into contact with youth justice services evidence unidentified language difficulties. These young people, therefore, have received little or no professional input in this area. Conversely, there is a dearth of research pertaining to criminality outcomes among those individuals with identified developmental language disorders (DLD) who have received such interventions. AIMS: To examine police-initiated contact and substance use outcomes of young adults with a history of identified DLD versus age-matched peers (AMP)...
November 21, 2017: International Journal of Language & Communication Disorders
https://www.readbyqxmd.com/read/29158765/usefulness-of-the-korean-developmental-screening-test-for-infants-and-children-for-the-evaluation-of-developmental-delay-in-korean-infants-and-children-a-single-center-study
#2
Chung-Hyuk Yim, Gun-Ha Kim, Baik-Lin Eun
Purpose: To evaluate the usefulness of the Korean Developmental Screening Test (K-DST) for infants and children for developmental delay assessment. Methods: This study was based on retrospective studies of the results of the K-DST, Preschool Receptive-Expressive Language Scale (PRES), Sequenced Language Scale for Infants (SELSI), Childhood Autism Rating Scale (CARS), Modified Checklist for Autism in Toddlers (M-CHAT), electroencephalography, magnetic resonance imaging, and extensive tests conducted in 209 of 1,403 patients, of whom 758 underwent the K-DST at the Korea University Guro Hospital between January 2015 and December 2016 and 645 were referred from local clinics between January 2015 and June 2016...
October 2017: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/29157666/cognitive-flexibility-in-preschool-children-with-and-without-stuttering-disorders
#3
Naomi Eichorn, Klara Marton, Steven Pirutinsky
PURPOSE: Multifactorial explanations of developmental stuttering suggest that difficulties in self-regulation and weak attentional flexibility contribute to persisting stuttering. We tested this prediction by examining whether preschool-age children who stutter (CWS) shift their attention less flexibly than children who do not stutter (CWNS) during a modified version of the Dimension Card Change Sort (DCCS), a reliable measure of attention switching for young children. METHODS: Sixteen CWS (12 males) and 30 children CWNS (11 males) participated in the study...
November 13, 2017: Journal of Fluency Disorders
https://www.readbyqxmd.com/read/29151094/glossolalia-and-aphasia-related-but-different-worlds
#4
Leila Chouiter, Jean-Marie Annoni
The word glossolalia, also referred to as "speaking in tongues," originates from the Greek "glossa" which means "language" and "Lalia" which means "speak." It simply means to talk language. On a linguistic perspective, glossolalia is characterized by almost no recognizable words or semantic content, apart from biblical words and phrases, with an overrepresentation of a small phonemes number, accelerated speech output, and modification of accents and melody. Its phonemic properties have been said to resemble those of the language(s) of the speaker...
2018: Frontiers of Neurology and Neuroscience
https://www.readbyqxmd.com/read/29141583/clinical-and-molecular-genetic-characterization-of-familial-mecp2-duplication-syndrome-in-a-chinese-family
#5
Xiaoyan Li, Hua Xie, Qian Chen, Xiongying Yu, Zhaoshi Yi, Erzhen Li, Ting Zhang, Jian Wang, Jianmin Zhong, Xiaoli Chen
BACKGROUND: Chromosomal duplication at the Xq28 region including the MECP2 gene, share consistent clinical phenotypes and a distinct facial phenotype known as MECP2 duplication syndrome. The typical clinical features include infantile hypotonia , mild dysmorphic features, a broad range of neurodevelopmental disorders, recurrent infections, and progressive spasticity. METHODS: This Chinese MECP2 duplication syndrome family includes six patients (five males and one female), and four asymptomatic female carriers...
November 15, 2017: BMC Medical Genetics
https://www.readbyqxmd.com/read/29139196/education-and-employment-outcomes-of-young-adults-with-a-history-of-developmental-language-disorder
#6
Gina Conti-Ramsden, Kevin Durkin, Umar Toseeb, Nicola Botting, Andrew Pickles
BACKGROUND: Developmental language disorder (DLD) presents a considerable barrier for young adults to engage in further education and training. Early studies with young adults with DLD revealed poor educational achievement and lack of opportunities to progress in education. More recent studies have provided more positive findings. Relatively sparse data exist, however, on current cohorts and the factors that predict outcomes. AIMS: To examine educational and employment outcomes in young adulthood in a sample of people with histories of DLD compared with an age-matched peer group without DLD...
November 15, 2017: International Journal of Language & Communication Disorders
https://www.readbyqxmd.com/read/29126347/language-profiles-in-young-children-with-autism-spectrum-disorder-a-community-sample-using-multiple-assessment-instruments
#7
Rose Nevill, Darren Hedley, Mirko Uljarević, Ensu Sahin, Johanna Zadek, Eric Butter, James A Mulick
This study investigated language profiles in a community-based sample of 104 children aged 1-3 years who had been diagnosed with autism spectrum disorder using Diagnostic and Statistical Manual of Mental Disorders (5th ed.) diagnostic criteria. Language was assessed with the Mullen scales, Preschool Language Scale, fifth edition, and Vineland-II parent-report. The study aimed to determine whether the receptive-to-expressive language profile is independent from the assessment instrument used, and whether nonverbal cognition, early communicative behaviors, and autism spectrum disorder symptoms predict language scores...
November 1, 2017: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/29121855/saccade-adaptation-deficits-in-developmental-dyslexia-suggest-disruption-of-cerebellar-dependent-learning
#8
Edward G Freedman, Sophie Molholm, Michael J Gray, Daniel Belyusar, John J Foxe
BACKGROUND: Estimates of the prevalence of developmental dyslexia in the general population range from 5% to as many as 10%. Symptoms include reading, writing, and language deficits, but the severity and mix of symptoms can vary widely across individuals. In at least some people with dyslexia, the structure and function of the cerebellum may be disordered. Saccadic adaptation requires proper function of the cerebellum and brainstem circuitry and might provide a simple, noninvasive assay for early identification and sub-phenotyping in populations of children who may have dyslexia...
November 9, 2017: Journal of Neurodevelopmental Disorders
https://www.readbyqxmd.com/read/29119716/episodic-memory-retrieval-in-adolescents-with-and-without-developmental-language-disorder-dld
#9
Joanna C Lee
BACKGROUND: Two reasons may explain the discrepant findings regarding declarative memory in developmental language disorder (DLD) in the literature. First, standardized tests are one of the primary tools used to assess declarative memory in previous studies. It is possible they are not sensitive enough to subtle memory impairment. Second, the system underlying declarative memory is complex, and thus results may vary depending on the types of encoding and retrieval processes measured (e...
November 8, 2017: International Journal of Language & Communication Disorders
https://www.readbyqxmd.com/read/29114746/distributional-learning-in-college-students-with-developmental-language-disorder
#10
Jessica Hall, Amanda Owen Van Horne, Karla K McGregor, Thomas Farmer
Purpose: This study examined whether college students with developmental language disorder (DLD) could use distributional information in an artificial language to learn about grammatical category membership in a way similar to their typically developing (TD) peers. Method: Seventeen college students with DLD and 17 TD college students participated in this task. We used an artificial grammar in which certain combinations of words never occurred during training. At test, participants had to use knowledge of category membership to determine which combinations were allowable in the grammar, even though they had not been heard...
November 9, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/29090309/procedural-motor-learning-in-children-with-specific-language-impairment
#11
Teenu Sanjeevan, Elina Mainela-Arnold
Purpose: Specific language impairment (SLI) is a developmental disorder that affects language and motor development in the absence of a clear cause. An explanation for these impairments is offered by the procedural deficit hypothesis (PDH), which argues that motor difficulties in SLI are due to deficits in procedural memory. The aim of this study was to test the PDH by examining the procedural motor learning abilities of children with and without SLI. Method: Thirteen children with SLI and 14 age-matched typically developing children completed the following procedural measures: (a) a knot-tying task as a measure of motor sequencing and (2) a mirror-drawing task as a measure of visual-motor adaptation...
November 9, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/29081756/the-locus-preservation-hypothesis-shared-linguistic-profiles-across-developmental-disorders-and-the-resilient-part-of-the-human-language-faculty
#12
Evelina Leivada, Maria Kambanaros, Kleanthes K Grohmann
Grammatical markers are not uniformly impaired across speakers of different languages, even when speakers share a diagnosis and the marker in question is grammaticalized in a similar way in these languages. The aim of this work is to demarcate, from a cross-linguistic perspective, the linguistic phenotype of three genetically heterogeneous developmental disorders: specific language impairment, Down syndrome, and autism spectrum disorder. After a systematic review of linguistic profiles targeting mainly English-, Greek-, Catalan-, and Spanish-speaking populations with developmental disorders (n = 880), shared loci of impairment are identified and certain domains of grammar are shown to be more vulnerable than others...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29074036/developmental-and-behavioral-aspects-of-mucopolysaccharidoses-with-brain-manifestations-neurological-signs-and-symptoms
#13
REVIEW
Elsa G Shapiro, Simon A Jones, Maria L Escolar
The mucopolysaccharidoses (MPS) are a group of rare, inherited lysosomal storage disorders, caused by mutations in lysosomal enzymes involved in the degradation of glycosaminoglycans (GAGs). The resulting accumulation of GAGs in the body leads to widespread tissue and organ dysfunction. The spectrum, severity, and progression rate of clinical manifestations varies widely between and within the different MPS types. In addition to somatic signs and symptoms, which vary between the different MPS disorders, patients with MPS I, II, III, and VII present with significant neurological signs and symptoms, including impaired cognitive abilities, difficulties in language and speech, and/or behavioral and sleep problems...
August 26, 2017: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/29073489/procedural-memory-and-speed-of-grammatical-processing-comparison-between-typically-developing-children-and-language-impaired-children
#14
Gillian M Clark, Jarrad A G Lum
BACKGROUND: Procedural memory has been proposed to underlie the acquisition of a range of skills including grammar, reading, and motor skills. In developmental language disorder (DLD) it has been suggested that procedural memory problems lead to the difficulties with grammar in this group. AIMS: This study aimed to extend previous research by exploring associations between procedural memory and a range of cognitive skills, in children with and without language impairments...
October 23, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29070031/17q23-2q23-3-de-novo-duplication-in-association-with-speech-and-language-disorder-learning-difficulties-incoordination-motor-skill-impairment-and-behavioral-disturbances-a-case-report
#15
Karen Wessel, Jehan Suleiman, Tamam E Khalaf, Shivendra Kishore, Arndt Rolfs, Ayman W El-Hattab
BACKGROUND: Chromosomal rearrangements involving 17q23 have been described rarely. Deletions at 17q23.1q23.2 have been reported in individuals with developmental delay and growth retardation, whereas duplications at 17q23.1q23.2 appear to segregate with clubfoot. Dosage alterations in the TBX2 and TBX4 genes, located in 17q23.2, have been proposed to be responsible for the phenotypes observed in individuals with 17q23.1q23.2 deletions and duplications. In this report, we present the clinical phenotype of a child with a previously unreported de novo duplication at 17q23...
October 25, 2017: BMC Medical Genetics
https://www.readbyqxmd.com/read/29062322/whole-gene-deletion-of-ebf3-supporting-haploinsufficiency-of-this-gene-as-a-mechanism-of-neurodevelopmental-disease
#16
Fátima Lopes, Gabriela Soares, Miguel Gonçalves-Rocha, Jorge Pinto-Basto, Patrícia Maciel
Mutations in early B cell factor 3 (EBF3) were recently described in patients with a neurodevelopmental disorder (NDD) that includes developmental delay/intellectual disability, ataxia, hypotonia, speech impairment, strabismus, genitourinary abnormalities, and mild facial dysmorphisms. Several large 10q terminal and interstitial deletions affecting many genes and including EBF3 have been described in the literature. However, small deletions (<1 MB) affecting almost exclusively EBF3 are not commonly reported...
2017: Frontiers in Genetics
https://www.readbyqxmd.com/read/29052014/predictive-validity-of-a-service-setting-based-measure-to-identify-infancy-mental-health-problems-a-population-based-cohort-study
#17
Janni Ammitzbøll, Lau Caspar Thygesen, Bjørn E Holstein, Anette Andersen, Anne Mette Skovgaard
Measures to identify infancy mental health problems are essential to guide interventions and reduce the risk of developmental psychopathology in early years. We investigated a new service-setting-based measure the Copenhagen Infant Mental Health Screening (CIMHS) within the general child health surveillance by community health nurses (CHN). The study population of 2973 infants was assessed by CIMHS at age 9-10 months. A subsample of 416 children was examined at age 1½ years, using parent interviews including the Child Behavior Checklist (CBCL 1½-5), Check List of Autism and Toddlers (CHAT), Infant-Toddler Symptom Checklist (ITSCL), and the Bayley Scales of Infant and Toddler Development (BSID) and observations of behavior, communication, and interaction...
October 20, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/29050641/white-matter-pathways-in-persistent-developmental-stuttering-lessons-from-tractography
#18
Vered Kronfeld-Duenias, Oren Civier, Ofer Amir, Ruth Ezrati-Vinacour, Michal Ben-Shachar
PURPOSE: Fluent speech production relies on the coordinated processing of multiple brain regions. This highlights the role of neural pathways that connect distinct brain regions in producing fluent speech. Here, we aim to investigate the role of the white matter pathways in persistent developmental stuttering (PDS), where speech fluency is disrupted. METHODS: We use diffusion weighted imaging and tractography to compare the white matter properties between adults who do and do not stutter...
September 13, 2017: Journal of Fluency Disorders
https://www.readbyqxmd.com/read/29043919/beyond-survival-5-year-neurodevelopmental-follow-up-of-a-cohort-of-preterm-infants-in-colombo-sri-lanka
#19
S P Sumanasena, D V Vipulaguna, M M Mendis, N S Gunawardena
BACKGROUND: There is a lack of information on long-term neurodevelopmental outcome in preterm neonates in low- and middle-income countries. OBJECTIVES: To describe the developmental attainments of preterm neonates followed up for 5 years and to identify the risk factors for impairment. METHOD: A prospective descriptive cohort study was undertaken in neonates of 34 weeks gestation born within a period of 12 months at a single tertiary maternity and neonatal unit in Colombo, Sri Lanka...
October 18, 2017: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/29040924/early-social-communication-in-infants-with-fragile-x-syndrome-and-infant-siblings-of-children-with-autism-spectrum-disorder
#20
Laura J Hahn, Nancy C Brady, Lindsay McCary, Lisa Rague, Jane E Roberts
BACKGROUND: Little research in fragile X syndrome (FXS) has prospectively examined early social communication. AIMS: To compare early social communication in infants with FXS, infant siblings of children with autism spectrum disorder (ASIBs), and typically developing (TD) infants. METHODS AND PROCEDURES: Participants were 18 infants with FXS, 21 ASIBs, and 22 TD infants between 7.5-14.5 months. Social communication was coded using the Communication Complexity Scale during the administration of Autism Observation Scale for Infants...
December 2017: Research in Developmental Disabilities
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