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https://www.readbyqxmd.com/read/27926554/intraoperative-archive-of-right-colonic-vascular-variability-aids-central-vascular-ligation-and-redefines-gastrocolic-trunk-of-henle-variants
#1
Jamal F Alsabilah, Syed A Razvi, Mahdi H Albandar, Nam K Kim
BACKGROUND: Vascular supply to the right colon has become an issue because of high variability and subsequent impact on minimally invasive surgery. Past cadaveric or radiologic anatomic assessments are noncomprehensive. OBJECTIVE: Intraoperative charting of right colonic arteriovenous anatomy was undertaken to determine the incidence and scope of vascular variations. DESIGN: Vascular anatomy variations were documented in snapshot images, captured during laparoscopic video recordings or through open surgical digital photography...
January 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/27924579/reconstructing-erk-signaling-in-the-drosophila-embryo-from-fixed-images
#2
Bomyi Lim, Carmeline J Dsilva, Ioannis G Kevrekidis, Stanislav Y Shvartsman
The early Drosophila embryo provides unique opportunities for quantitative studies of ERK signaling. This system is characterized by simple anatomy, the ease of obtaining large numbers of staged embryos, and the availability of powerful tools for genetic manipulation of the ERK pathway. Here, we describe how these experimental advantages can be combined with recently developed microfluidic devices for high throughput imaging of ERK activation dynamics. We focus on the stage during the third hour of development, when ERK activation is essential for patterning of the future nerve cord...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27923997/insights-into-the-mechanisms-of-eukaryotic-translation-gained-with-ribosome-profiling
#3
Dmitry E Andreev, Patrick B F O'Connor, Gary Loughran, Sergey E Dmitriev, Pavel V Baranov, Ivan N Shatsky
The development of Ribosome Profiling (RiboSeq) has revolutionized functional genomics. RiboSeq is based on capturing and sequencing of the mRNA fragments enclosed within the translating ribosome and it thereby provides a 'snapshot' of ribosome positions at the transcriptome wide level. Although the method is predominantly used for analysis of differential gene expression and discovery of novel translated ORFs, the RiboSeq data can also be a rich source of information about molecular mechanisms of polypeptide synthesis and translational control...
December 6, 2016: Nucleic Acids Research
https://www.readbyqxmd.com/read/27923574/assimilation-of-optical-and-radar-remote-sensing-data-in-3d-mapping-of-soil-properties-over-large-areas
#4
Laura Poggio, Alessandro Gimona
Soil is very important for many land functions. To achieve sustainability it is important to understand how soils vary over space in the landscape. Remote sensing data can be instrumental in mapping and spatial modelling of soil properties, resources and their variability. The aims of this study were to compare satellite sensors (MODIS, Landsat, Sentinel-1 and Sentinel-2) with varying spatial, temporal and spectral resolutions for Digital Soil Mapping (DSM) of a set of soil properties in Scotland, evaluate the potential benefits of adding Sentinel-1 data to DSM models, select the most suited mix of sensors for DSM to map the considered set of soil properties and validate the results of topsoil (2D) and whole profile (3D) models...
December 3, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27923064/sparse-regression-based-structure-learning-of-stochastic-reaction-networks-from-single-cell-snapshot-time-series
#5
Anna Klimovskaia, Stefan Ganscha, Manfred Claassen
Stochastic chemical reaction networks constitute a model class to quantitatively describe dynamics and cell-to-cell variability in biological systems. The topology of these networks typically is only partially characterized due to experimental limitations. Current approaches for refining network topology are based on the explicit enumeration of alternative topologies and are therefore restricted to small problem instances with almost complete knowledge. We propose the reactionet lasso, a computational procedure that derives a stepwise sparse regression approach on the basis of the Chemical Master Equation, enabling large-scale structure learning for reaction networks by implicitly accounting for billions of topology variants...
December 2016: PLoS Computational Biology
https://www.readbyqxmd.com/read/27922592/distributed-solar-photovoltaic-array-location-and-extent-dataset-for-remote-sensing-object-identification
#6
Kyle Bradbury, Raghav Saboo, Timothy L Johnson, Jordan M Malof, Arjun Devarajan, Wuming Zhang, Leslie M Collins, Richard G Newell
Earth-observing remote sensing data, including aerial photography and satellite imagery, offer a snapshot of the world from which we can learn about the state of natural resources and the built environment. The components of energy systems that are visible from above can be automatically assessed with these remote sensing data when processed with machine learning methods. Here, we focus on the information gap in distributed solar photovoltaic (PV) arrays, of which there is limited public data on solar PV deployments at small geographic scales...
December 6, 2016: Scientific Data
https://www.readbyqxmd.com/read/27921994/the-structure-of-sv40-large-t-hexameric-helicase-in-complex-with-at-rich-origin-dna
#7
Dahai Gai, Damian Wang, Shu-Xing Li, Xiaojiang S Chen
DNA replication is a fundamental biological process. The initial step in eukaryotic DNA replication is the assembly of the pre-initiation complex, including the formation of two head-to-head hexameric helicases around the replication origin. How these hexameric helicases interact with their origin dsDNA remains unknown. Here, we report the co-crystal structure of the SV40 Large-T Antigen (LT) hexameric helicase bound to its origin dsDNA. The structure shows that the six subunits form a near-planar ring that interacts with the origin, so that each subunit makes unique contacts with the DNA...
December 6, 2016: ELife
https://www.readbyqxmd.com/read/27917184/studying-secondary-growth-and-bast-fiber-development-the-hemp-hypocotyl-peeks-behind-the-wall
#8
Marc Behr, Sylvain Legay, Eva Žižková, Václav Motyka, Petre I Dobrev, Jean-Francois Hausman, Stanley Lutts, Gea Guerriero
Cannabis sativa L. is an annual herbaceous crop grown for the production of long extraxylary fibers, the bast fibers, rich in cellulose and used both in the textile and biocomposite sectors. Despite being herbaceous, hemp undergoes secondary growth and this is well exemplified by the hypocotyl. The hypocotyl was already shown to be a suitable model to study secondary growth in other herbaceous species, namely Arabidopsis thaliana and it shows an important practical advantage, i.e., elongation and radial thickening are temporally separated...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27911955/scholarly-context-adrift-three-out-of-four-uri-references-lead-to-changed-content
#9
Shawn M Jones, Herbert Van de Sompel, Harihar Shankar, Martin Klein, Richard Tobin, Claire Grover
Increasingly, scholarly articles contain URI references to "web at large" resources including project web sites, scholarly wikis, ontologies, online debates, presentations, blogs, and videos. Authors reference such resources to provide essential context for the research they report on. A reader who visits a web at large resource by following a URI reference in an article, some time after its publication, is led to believe that the resource's content is representative of what the author originally referenced...
2016: PloS One
https://www.readbyqxmd.com/read/27909518/symptoms-in-atrial-fibrillation-a-contemporary-review-and-future-directions
#10
REVIEW
Steven T Heidt Bs, Anna Kratz PhD, Kayvan Najarian PhD, Afton L Hassett PsyD, Hakan Oral Md, Richard Gonzalez PhD, Brahmajee K Nallamothu Md Mph, Daniel Clauw Md, Hamid Ghanbari Md Mph
Atrial fibrillation (AF) is the most prevalent arrhythmia leading to hospital admissions in the United States. The majority of patients with AF report symptoms associated with this condition that can lead to a decrease in health related quality of life (HRQOL) and functional status. Therefore, along with reducing the risk of stroke and mortality, improvements in such symptoms are important therapeutic goals in the management of patients with AF. Our current understanding of how AF and symptoms are linked is hampered by the dominant assessment paradigm, where symptoms thought to be associated with AF are measured at a single point in time (frequently at a clinic visit)...
June 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/27908704/on-the-relationship-between-cell-cycle-analysis-with-ergodic-principles-and-age-structured-cell-population-models
#11
K Kuritz, D Stöhr, N Pollak, F Allgöwer
Cyclic processes, in particular the cell cycle, are of great importance in cell biology. Continued improvement in cell population analysis methods like fluorescence microscopy, flow cytometry, CyTOF or single-cell omics made mathematical methods based on ergodic principles a powerful tool in studying these processes. In this paper, we establish the relationship between cell cycle analysis with ergodic principles and age structured population models. To this end, we describe the progression of a single cell through the cell cycle by a stochastic differential equation on a one dimensional manifold in the high dimensional dataspace of cell cycle markers...
November 28, 2016: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/27908026/resonant-metalenses-for-flexural-waves-in-plates
#12
Andrea Colombi
The dispersion curves of a cluster of closely spaced rods supported by a thin plate are characterised by subwavelength bandgaps and slow group velocities induced by local resonance effects. A recent analytical study [Williams, Roux, Rupin, and Kuperman (2015). Phys. Rev. B 91, 104307], has shown how the slow velocity branch depends, amongst other parameters, on the height of the rods that make up the cluster. Such metamaterial, offering easy-to-tune spatial velocity gradients, is a perfect candidate for building gradient index lenses such as Luneburg, Maxwell, and 90° rotating...
November 2016: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/27906259/spatiotemporal-blue-noise-coded-aperture-design-for-multi-shot-compressive-spectral-imaging
#13
Claudia V Correa, Henry Arguello, Gonzalo R Arce
Multi-shot coded aperture snapshot spectral imaging (CASSI) systems capture the spectral information of a scene using a small set of coded focal plane array (FPA) compressive measurements. Compressed sensing (CS) reconstruction algorithms are then used to reconstruct the underlying spectral 3D data cube from an underdetermined system of linear equations. Multiple snapshots result in a less ill-posed inverse problem and improved reconstructions. The only varying components in CASSI are the coded apertures, whose structure is crucial inasmuch as they determine the minimum number of FPA measurements needed for correct image reconstruction and the corresponding attainable quality...
December 1, 2016: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/27906120/one-health-training-research-and-outreach-in-north-america
#14
REVIEW
Cheryl Stroud, Bruce Kaplan, Jenae E Logan, Gregory C Gray
BACKGROUND: The One Health (OH) concept, formerly referred to as 'One Medicine' in the later part of the 20th century, has gained exceptional popularity in the early 21st century, and numerous academic and non-academic institutions have developed One Health programs. OBJECTIVES: To summarize One Health training, research, and outreach activities originating in North America. METHODS: We used data from extensive electronic records maintained by the One Health Commission (OHC) (www...
2016: Infection Ecology & Epidemiology
https://www.readbyqxmd.com/read/27897429/temporal-variability-of-bacterial-communities-in-cryoconite-on-an-alpine-glacier
#15
Andrea Franzetti, Federico Navarra, Ilario Tagliaferri, Isabella Gandolfi, Giuseppina Bestetti, Umberto Minora, Roberto Sergio Azzoni, Guglielmina Diolaiuti, Claudio Smiraglia, Roberto Ambrosini
Cryoconite holes, i.e. small ponds that form on glacier surface, are considered the most biologically active environments on glaciers. Bacterial communities in these environments have been extensively studied, but often through snapshot studies based on the assumption of a general stability of community structure. In this study, we investigated the temporal variation of bacterial communities in cryoconite holes on the Forni Glacier (Italian Alps) by high throughput DNA sequencing. We found a temporal change of bacterial communities, with autotrophic Cyanobacteria populations dominating communities after snowmelt, and heterotrophic Sphingobacteriales populations increasing in abundance later in the season...
November 29, 2016: Environmental Microbiology Reports
https://www.readbyqxmd.com/read/27894723/plastic-debris-and-microplastics-along-the-beaches-of-the-strait-of-hormuz-persian-gulf
#16
Abolfazl Naji, Zinat Esmaili, Farhan R Khan
Currently little is known about the prevalence of plastics and microplastics (MPs) in the Persian Gulf. Five sampling stations were selected along the Strait of Hormuz (Iran) that exhibited different levels of industrialization and urbanization, and included a marine protected area. Debris was observed and sediments were collected for MPs extraction via fluidization/floatation methodology. The order of MP abundance (par/kg) generally reflected the level of anthropogenic activity: Bostanu (1258±291)>Gorsozan (122±23)>Khor-e-Yekshabeh (26±6)>Suru (14±4)>Khor-e-Azini (2±1)...
November 25, 2016: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/27881480/generation-of-signs-within-semantic-and-phonological-categories-data-from-deaf-adults-and-children-who-use-american-sign-language
#17
Jennifer S Beal-Alvarez, Daileen M Figueroa
Two key areas of language development include semantic and phonological knowledge. Semantic knowledge relates to word and concept knowledge. Phonological knowledge relates to how language parameters combine to create meaning. We investigated signing deaf adults' and children's semantic and phonological sign generation via one-minute tasks, including animals, foods, and specific handshapes. We investigated the effects of chronological age, age of sign language acquisition/years at school site, gender, presence of a disability, and geographical location (i...
November 23, 2016: Journal of Deaf Studies and Deaf Education
https://www.readbyqxmd.com/read/27881245/the-transplantex-initiative
#18
EDITORIAL
Seiamak Bahram, Raphael Carapito, Pierre-Antoine Gourraud, Dominique Charron
TRANSPLANTEX, a French "investment for the future" initiated consortium of leading transplant units and research laboratories across France and a number of European countries aims to unravel, through mainly high-throughput genomics (and other omics) analyses of donor and recipients, novel (a) non-HLA, histocompatibility antigens, whether inside, or outside the MHC; (b) pre/post transplantation biomarkers. This shall lead to our better understanding of the pathophysiology of (and eventually designing better therapeutics for) the graft-versus-host disease in hematopoietic cell transplants and that of chronic graft rejection after kidney transplant...
November 2016: Human Immunology
https://www.readbyqxmd.com/read/27881038/-enhance-her-pleasure-and-your-grip-strength-men-s-health-magazine-and-pseudo-reciprocal-pleasure
#19
Chelsey Nicole Porter, Nick Douglas, Martine Collumbien
This paper provides a snapshot of the Top Ten free, digital Men's Health magazine articles, accessed on a randomly selected day, that can be viewed as a collection; both a product for readership consumption and a construct of readership priorities. Through close textual analysis, we examine how discourses about masculinity, heterosex and consumerism have intersected to create a model of masculinity based on the discipline of male pleasure, which impacts on men's approach to female pleasure and gender dynamics...
November 24, 2016: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/27880048/using-a-few-snapshots-to-distinguish-mountains-from-waves-weak-factorial-invariance-in-the-context-of-trait-state-research
#20
E L Hamaker, N K Schuurman, E A O Zijlmans
In this article, we show that the underlying dimensions obtained when factor analyzing cross-sectional data actually form a mix of within-person state dimensions and between-person trait dimensions. We propose a factor analytical model that distinguishes between four independent sources of variance: common trait, unique trait, common state, and unique state. We show that by testing whether there is weak factorial invariance across the trait and state factor structures, we can tackle the fundamental question first raised by Cattell; that is, are within-person state dimensions qualitatively the same as between-person trait dimensions? Furthermore, we discuss how this model is related to other trait-state factor models, and we illustrate its use with two empirical data sets...
November 23, 2016: Multivariate Behavioral Research
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