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https://www.readbyqxmd.com/read/29786664/enable-2017-the-first-european-phd-and-post-doc-symposium-session-3-in-vitro-to-in-vivo-modeling-life-in-3d
#1
Gianmarco Di Mauro, Ambra Dondi, Giovanni Giangreco, Alexander Hogrebe, Elja Louer, Elisa Magistrati, Meeli Mullari, Gemma Turon, Wouter Verdurmen, Helena Xicoy Cortada, Sanja Zivanovic
The EUROPEAN ACADEMY FOR BIOMEDICAL SCIENCE (ENABLE) is an initiative funded by the European Union Horizon 2020 program involving four renowned European research institutes (Institute for Research in Biomedicine-IRB Barcelona, Spain; Radboud Institute for Molecular Life Sciences-RIMLS, the Netherlands; Novo Nordisk Foundation Center for Protein Research-NNF CPR, Denmark; European School of Molecular Medicine-SEMM, Italy) and an innovative science communication agency (Scienseed). With the aim to promote biomedical science of excellence in Europe, ENABLE organizes an annual three-day international event...
May 22, 2018: Journal of Personalized Medicine
https://www.readbyqxmd.com/read/29784347/simultaneous-sampling-of-dissolved-orthophosphate-and-ammonium-in-freshwaters-using-diffusive-gradients-in-thin-films-with-a-mixed-binding-phase
#2
Zhongmin Feng, Ni Wang, Manli He, Lan Yang, Yun Wang, Ting Sun
A new diffusive gradients in thin films (DGT) technique with a micro-sized biochar-zeolite-zirconium oxide mixed binding phase is described for simultaneous sampling of dissolved orthophosphate and ammonium in freshwaters. The performance of mixed binding layer (MBL) DGT technique was characterized by evaluation of the following parameters: (1) the adsorption efficiency of phosphate and ammonium by the mixed binding phase, (2) the elution efficiency, (3) the time-series accumulation, and (4) the influences of pH, coexisting cations and DOC on DGT uptake...
August 15, 2018: Talanta
https://www.readbyqxmd.com/read/29783141/graphene-oxide-and-carbon-nanodots-co-modified-biobr-nanocomposites-with-enhanced-photocatalytic-4-chlorophenol-degradation-and-mechanism-insight
#3
Songying Qu, Yuhan Xiong, Jun Zhang
Non-metallic graphene oxide (GO) and carbon nanodots (CDots) co-doped BiOBr ternary system (GO/CDots/BiOBr) were successfully synthesized via a simple one-step solvothermal process. The compositional characterization, optical and electrical properties of photocatalysts were investigated in detail. The prepared ternary photocatalysts possessed the excellent visible-light driven photocatalytic 4-chlorophenol (4-CP) degradation. Additionally, the 4-CP removal efficiencies decreased in the order of GO/CDots/BiOBr (88...
May 15, 2018: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29782953/electrodermal-reactivity-to-emotional-stimuli-in-healthy-subjects-and-patients-with-disorders-of-consciousness
#4
Jacques Luauté, Anne Dubois, Lizette Heine, Chloé Guironnet, Ariane Juliat, Valérie Gaveau, Barbara Tillmann, Fabien Perrin
OBJECTIVES: After a coma, one major challenge is the detection of awareness in patients with disorders of consciousness. In some patients, the only manifestation indicative of awareness is an appropriate emotional response. Preferred music is a powerful medium to elicit emotions and auto-biographical memory. Furthermore, music has been shown to improve cognitive functions both in healthy subjects and patients with neurological impairment. We hypothesized that signs of awareness could be enhanced in some patients with disorders of consciousness under appropriate emotional stimulation such as preferred music and also probably preferred odors...
May 18, 2018: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29779374/molecularly-imprinted-polymers-for-compound-specific-isotope-analysis-of-polar-organic-micropollutants-in-aquatic-environments
#5
Rani Bakkour, Jakov Bolotin, Börje Sellergren, Thomas B Hofstetter
Compound-specific isotope analysis (CSIA) of polar organic micropollutants in environmental waters requires a processing of large sample volumes to obtain the required analyte masses for analysis by gas chromatography / isotope-ratio mass spectrometry (GC/IRMS). However, the accumulation of organic matter of unknown isotopic composition in standard enrichment procedures currently compromises the accurate determination of isotope ratios. We explored the use of molecularly-imprinted polymers (MIPs) for selective analyte enrichment for 13C/12C and 15N/14N ratio measurements by GC/IRMS using 1H-benzotriazole, a typical corrosion inhibitor in dishwashing detergents, as example of a widely detected polar organic micropollutant...
May 20, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29778675/groundwater-contamination-and-land-drainage-induce-divergent-responses-in-boreal-spring-ecosystems
#6
Kaisa Lehosmaa, Jussi Jyväsjärvi, Jari Ilmonen, Pekka M Rossi, Lauri Paasivirta, Timo Muotka
Degradation of freshwater ecosystems has engendered legislative mandates for the protection and management of surface waters while groundwater-dependent ecosystems (GDEs) have received much less attention. This is so despite biodiversity and functioning of GDEs are currently threatened by several anthropogenic stressors, particularly intensified land use and groundwater contamination. We assessed the impacts of land drainage (increased input of dissolved organic carbon, DOC, from peatland drainage) and impaired groundwater chemical quality (NO3 - -N enrichment from agricultural or urban land use) on biodiversity and ecosystem functioning in 20 southern Finnish cold-water springs using several taxonomic and functional measures...
May 17, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29777311/sufficiency-of-curing-in-high-viscosity-bulk-fill-resin-composites-with-enhanced-opacity
#7
Nicoleta Ilie
OBJECTIVES: The study aims analyzing if improved opacity in modern high-viscosity bulk-fill resin composites (BF-RBC) contradicts with the sufficiency of curing and to assess material's tolerance to less ideal curing conditions. MATERIALS AND METHODS: Simulated large cavities (10 × 6) mm were filled in one increment with three BF-RBCs (Filtek One, FO; Tetric Evo Ceram Bulk Fill, TEC-BF; SonicFill2, SF2). One central and two peripheral (4 mm apart from the center) micromechanical property line-profiles (HV, Vickers hardness; YHU , indentation modulus) were measured in 0...
May 18, 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29770812/reduction-photo-dual-responsive-polymeric-prodrug-nanoparticles-for-programmed-sirna-and-doxorubicin-delivery
#8
Ming Wu, Jiong Li, Xinyi Lin, Zuwu Wei, Da Zhang, Bixing Zhao, Xiaolong Liu, Jingfeng Liu
Dual and multi-stimuli responsive polymeric nanoparticles that respond to two or more signals can further improve drug release performance compared with nanoparticles that respond to a single stimulus. However, usage of such nanoparticles to deliver siRNA and chemotherapeutic drugs in a sequential manner are currently very rare; meanwhile, this technology is vital to optimize the efficacy of chemotherapy towards cancer cells with multidrug resistance. By loading o-nitrobenzyl ester derivative caged DOX (DOC) into the inner poly(lactic-co-glycolic acid) (PLGA) core and adsorbing siRNA of P-gp protein onto the cationic polymeric shell derived from a disulfide-containing alkyl modified polyethylenimine (C16-S-S-PEI), here, a reduction/photo dual responsive device (RPDRD) is successfully designed for programmed P-gp siRNA and doxorubicin delivery...
May 17, 2018: Biomaterials Science
https://www.readbyqxmd.com/read/29770146/effects-of-20-hz-repetitive-transcranial-magnetic-stimulation-on-disorders-of-consciousness-a-resting-state-electroencephalography-study
#9
Fangping He, Min Wu, Fanxia Meng, Yangfan Hu, Jian Gao, Zhongqin Chen, Wangxiao Bao, Kehong Liu, Benyan Luo, Gang Pan
Repetitive transcranial magnetic stimulation (rTMS) has been proposed as an experimental approach for the treatment of disorders of consciousness (DOC). To date, there has been little research into the use of rTMS in DOC and the therapeutic effects have been variously documented. This study aimed to examine the effects of 20 Hz rTMS on the electroencephalography (EEG) reactivity and clinical response in patients with DOC and to explore the neuromodulatory effects of high-frequency rTMS. In this randomized, sham-controlled, crossover study, real or sham 20 Hz rTMS was applied to the left primary motor cortex (M1) of patients with DOC for 5 consecutive days...
2018: Neural Plasticity
https://www.readbyqxmd.com/read/29767310/the-removal-of-silver-nanoparticle-by-titanium-tetrachloride-and-modified-sodium-alginate-composite-coagulants-floc-properties-membrane-fouling-and-floc-recycle
#10
Ziyang Wang, Yan Wang, Cong Yu, Yanxia Zhao, Meixia Fan, Baoyu Gao
In this study, a modified sodium alginate (MSA) composited with TiCl4 was used to treat the synthetic Ag nanoparticles (AgNPs) water in coagulation-ultrafiltration process. The floc properties and membrane fouling of TiCl4 and MSA composite coagulants (TiCl4 + MSA) were investigated by a laser diffraction instrument and ultrafiltration fouling model. The recycle of the AgNP-containing flocs was evaluated by XRD and photocatalytic experiments. The results showed that TiCl4 + MSA could achieve better coagulation performance than TiCl4 alone with AgNP and DOC removal up to 97 and 59% at the optimum condition (pH = 5 and dosage = 12 mg TiCl4 /L)...
May 16, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29765092/pilot-scale-study-on-catalytic-ozonation-of-bio-treated-dyeing-and-finishing-wastewater-using-recycled-waste-iron-shavings-as-a-catalyst
#11
Jieting Ma, Yunlu Chen, Jianxin Nie, Luming Ma, Yuanxing Huang, Liang Li, Yan Liu, Zhigang Guo
A pilot scale reactor with an effective volume of 2.93 m3 was built in-situ and run in both batch and continuous modes to investigate the removal for organic pollutants in bio-treated dyeing and finishing wastewater by heterogeneous catalytic ozonation under neutral pH with waste iron shavings as a catalyst. Experimental results showed that both running modes were able to reduce the chemical oxygen demand (COD) from 132-148 mg/L to a level below the discharge criteria (<80 mg/L) within 15-30 mins under several conditions...
May 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29762807/i-really-didn-t-want-to-become-a-doctor-tales-and-musings-from-a-retired-family-doc-after-over-50-plus-years-of-practice
#12
Aimee Burke Valeras
No abstract text is available yet for this article.
May 2018: Family Medicine
https://www.readbyqxmd.com/read/29761355/application-of-triolein-embedded-cellulose-acetate-membrane-tecam-passive-sampler-to-study-phase-distribution-of-hexabromocyclododecanes-hbcds-in-sediment
#13
Jianfeng Tang, Xinhu Li, Xinwei Yu, Gang Li, Sardar Khan, Chao Cai
Hexabromocyclododecanes (HBCDs) are a class of widely used brominated flame retardants (BFRs) that exhibit strong hydrophobicity. The ubiquity and persistence of HBCDs in sediment have attracted significant attention because of public health concerns. The environmental fate and ecological risks of HBCDs closely depend on their phase distribution in sediments. However, little information is available regarding the freely dissolved concentrations (C free ) of HBCDs in sediment porewater. In this study, we developed a method to measure C free of HBCDs in sediment porewater using triolein-embedded cellulose acetate membranes (TECAM)...
May 14, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29758887/arsenic-rich-shallow-groundwater-in-sandy-aquifer-systems-buffered-by-rising-carbonate-waters-a-geochemical-case-study-from-mannar-island-sri-lanka
#14
U G C Bandara, Saranga Diyabalanage, Christian Hanke, Robert van Geldern, Johannes A C Barth, Rohana Chandrajith
Major ion, trace elements, and stable isotope analyses were performed on groundwater samples collected from Mannar Island in the northern Indian Ocean. Arsenic concentrations up to 34μg/L have been observed in groundwater samples from the island. In addition, 23% of extensively used shallow drinking water wells showed higher arsenic contents than the recommended value by the World Health Organization (10μg/L). Groundwater in the island showed pH values between 6.9 and 8.9 and was dominated by Na+ , K+ , Ca2+ , Mg2+ , HCO3 - , Cl- and SO4 2- ...
August 15, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29753228/negative-effects-of-climate-change-on-upland-grassland-productivity-and-carbon-fluxes-are-not-attenuated-by-nitrogen-status
#15
Samuel Eze, Sheila M Palmer, Pippa J Chapman
Effects of climate change on managed grassland carbon (C) fluxes and biomass production are not well understood. In this study, we investigated the individual and interactive effects of experimental warming (+3 °C above ambient summer daily range of 9-12 °C), supplemental precipitation (333 mm +15%) and drought (333 mm -23%) on plant biomass, microbial biomass C (MBC), net ecosystem exchange (NEE) and dissolved organic C (DOC) flux in soil cores from two upland grasslands of different soil nitrogen (N) status (0...
May 9, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29751255/measuring-restoration-progress-using-pore-and-surface-water-chemistry-across-a-chronosequence-of-formerly-afforested-blanket-bogs
#16
Paul P J Gaffney, Mark H Hancock, Mark A Taggart, Roxane Andersen
During the restoration of degraded bogs and other peatlands, both habitat and functional recovery can be closely linked with nutrient cycling, which is reflected in pore- and surface-water chemistry. Several peatland restoration studies have shown that the time required for recovery of target conditions is slow (>10 years); for heavily-impacted, drained and afforested peatlands of northern Scotland, recovery time is unknown. We monitored pore- and surface-water chemistry across a chronosequence of formerly drained, afforested bog restoration sites spanning 0-17 years, using a space-for-time substitution, and compared them with open blanket bog control sites...
May 7, 2018: Journal of Environmental Management
https://www.readbyqxmd.com/read/29748822/vascular-plant-and-bryophyte-species-richness-in-response-to-water-quality-in-lowland-spring-niches-with-different-anthropogenic-impacts
#17
Katarzyna Puczko, Piotr Zieliński, Szymon Jusik, Anita Kołakowska, Elżbieta Jekatierynczuk-Rudczyk
Many freshwater ecosystems face severe threats from anthropogenic disturbances. In the field, we investigated the morphology of spring niches and the species richness of vascular plants and bryophytes in 16 springs, draining the quaternary aquifers, located in two different environments-an urban area (city of Białystok) and a protected area (Knyszyn Forest Landscape Park, NE Poland). In total, 47 vascular plant and 45 bryophyte species were recorded, representing mostly crenophytes including protected species...
May 10, 2018: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29747945/financial-conflicts-of-interest-among-authors-of-urology-clinical-practice-guidelines
#18
Austin Carlisle, Aaron Bowers, Cole Wayant, Chase Meyer, Matt Vassar
BACKGROUND: Recent studies have highlighted the presence of disclosed and undisclosed financial conflicts of interest among authors of clinical practice guidelines. OBJECTIVE: We sought to determine to what extent urology guideline authors receive and report industry payments in accordance with the Physician Payment Sunshine Act. DESIGN, SETTING, AND PARTICIPANTS: We selected the 13 urology guidelines that were published by the American Urological Association (AUA) after disclosure was mandated by the Physician Payment Sunshine Act...
May 7, 2018: European Urology
https://www.readbyqxmd.com/read/29745166/-seasonal-changes-of-optical-absorption-properties-of-river-and-lake-in-east-liaohe-river-basin-northeast-china
#19
Yan Yan Song, Dong Hui Su, Tian Tian Shao
The absorption characteristics of optically active constituents (OACs) in water column are important optical properties and basic parameters of establishing the inverse analysis model. Comparative analyses about seasonal variability of the optical absorption characteristics (phytoplankton, non-algal particles and chromophoric dissolved organic matter absorption characteristics) and water quality status of East Liaohe River basin were conducted based on the water samples in Erlong-hu Reservoir collected in June, September and October of 2011 and samples in East Liaohe River in October of 2012...
June 18, 2017: Ying Yong Sheng Tai Xue Bao, the Journal of Applied Ecology
https://www.readbyqxmd.com/read/29740372/large-scale-brain-simulation-and-disorders-of-consciousness-mapping-technical-and-conceptual-issues
#20
Michele Farisco, Jeanette H Kotaleski, Kathinka Evers
Modeling and simulations have gained a leading position in contemporary attempts to describe, explain, and quantitatively predict the human brain's operations. Computer models are highly sophisticated tools developed to achieve an integrated knowledge of the brain with the aim of overcoming the actual fragmentation resulting from different neuroscientific approaches. In this paper we investigate the plausibility of simulation technologies for emulation of consciousness and the potential clinical impact of large-scale brain simulation on the assessment and care of disorders of consciousness (DOCs), e...
2018: Frontiers in Psychology
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