Lucy Gately, C Mesía, J M Sepúlveda, S Del Barco, E Pineda, R Gironés, J Fuster, M Dumas, S Gill, L M Navarro, A Herrero, A Dowling, R de Las Peñas, M A Vaz, M Alonso, Z Lwin, R Harrup, S Peralta, A Long, P Perez-Segura, E Ahern, C O Garate, M Wong, R Campbell, K Cuff, R Jennens, O Gallego, C Underhill, M Martinez-Garcia, M Covela, A Cooper, S Brown, M Rosenthal, J Torres, I M Collins, P Gibbs, C Balana
PURPOSE: The impact of age on optimal management of glioblastoma remains unclear. A recent combined analysis of two randomised trials, GEINO14-01 and EX-TEM, found no benefit from extending post-radiation temozolomide in newly diagnosed glioblastoma. Here, we explore the impact of age. METHODS: Relevant intergroup statistics were used to identify differences in tumour, treatment and outcome characteristics based on age with elderly patients (EP) defined as age 65 years and over...
April 17, 2024: Journal of Neuro-oncology