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https://www.readbyqxmd.com/read/28728282/-epidemiologic-study-of-tear-film-lipid-layer-thickness-measurement-in-the-population-of-taishitun-community-in-beijing
#1
Q F Liang, X H Du, Y D Su, N L Wang, Z J Wei, Antoine Labbé
Objective: To investigate the distribution of tear film lipid layer thickness (LLT) and the relationship between symptoms and signs of dry eye and tear film LLT in the population of Taishitun Community in Beijing. Methods: A cross-sectional study. From May 2016 to August 2016, three streets of Taishitun Community were randomly selected as survey districts and 540 persons were taken as investigation subjects. Every participant completed 6 items of dry eye examinations as follows: questionnaire (Ocular Surface Disease Index, OSDI), measurement of tear film LLT, tear film break-up time (TBUT), corneal and conjunctival staining, SchirmerⅠtest and the infrared meibomian photography...
July 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28728200/-heart-failure-a-model-for-multimorbidity
#2
Gülmisal Güder, Georg Ertl
Heart failure frequently is the consequence of different cardiac diseases and is associated with multiple cardiac and non-cardiac co-morbidities. It may be exemplary for multi-morbidity in the elderly, has negative impact on various organ systems and may induce further comorbidities. The following article addresses heart failure as a multisystem disorder.
July 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28728162/realistic-lenalidomide-dose-adjustment-strategy-for-transplant-ineligible-elderly-patients-with-relapsed-refractory-multiple-myeloma-japanese-real-world-experience
#3
Aya Nakaya, Shinya Fujita, Atsushi Satake, Takahisa Nakanishi, Yoshiko Azuma, Yukie Tsubokura, Masaaki Hotta, Hideaki Yoshimura, Kazuyoshi Ishii, Tomoki Ito, Shosaku Nomura
Lenalidomide is an immunomodulatory drug administered orally in the treatment of multiple myeloma. Some elderly patients require a reduced lenalidomide dose because of comorbidities and/or adverse events. This study investigated the actual dose of lenalidomide in elderly patients, finding that most received reduced (5-10 mg) doses. The most common reasons for dose reduction were renal dysfunction (54% of patients), fatigue (grade ≥3; 20%), hematologic disorder (grade ≥3; 14%), and rash (grade ≥3; 9%)...
July 21, 2017: Acta Haematologica
https://www.readbyqxmd.com/read/28728093/obsessive-compulsive-disorder-in-the-elderly-a-report-from-the-international-college-of-obsessive-compulsive-disorders-icocs
#4
B Dell'Osso, B Benatti, C I Rodriguez, C Arici, C Palazzo, A C Altamura, E Hollander, N Fineberg, D J Stein, H Nicolini, N Lanzagorta, D Marazziti, S Pallanti, M Van Ameringen, C Lochner, O Karamustafalioglu, L Hranov, M Figee, L Drummond, J Grant, D Denys, D Cath, J M Menchon, J Zohar
INTRODUCTION: Obsessive-compulsive disorder (OCD) is a highly disabling condition, with frequent early onset. Adult/adolescent OCD has been extensively investigated, but little is known about prevalence and clinical characterization of geriatric patients with OCD (G-OCD≥65years). The present study aimed to assess prevalence of G-OCD and associated socio-demographic and clinical correlates in a large international sample. METHODS: Data from 416 outpatients, participating in the ICOCS network, were assessed and categorized into 2 groups, age<vs≥65years, and then divided on the basis of the median age of the sample (age<vs≥42years)...
July 4, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28728083/sleep-disturbances-and-risk-of-falls-in-an-old-chinese-population-rugao-longevity-and-ageing-study
#5
Teng Ma, Guoping Shi, Yinsheng Zhu, Yong Wang, Xuefeng Chu, Xiaoyan Jiang, Zuyun Liu, Jian Cai, Hongfei Wang, Li Jin, Zhendong Wang, Xiaofeng Wang
BACKGROUND: To explore the relationship between sleep disturbances and falls in an elderly Chinese population. METHODS: Data from 1726 individuals aged 70-87 years from the Rugao Longevity and Ageing Study were used. The Pittsburgh Sleep Quality Index (PSQI) was used to assess sleep variables. Outcomes were falls ≥1 time per year and falls ≥2 times per year. RESULTS: A total of 22.7% of the participants experienced ≥1 fall, and 9.8% experienced ≥2 falls per year...
July 12, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28728082/oral-infections-comorbidities-and-sensory-evidences-in-elderly-cross-sectional-study
#6
Nathalia Santos Viana Silva, Luciana Alvarenga da Silva, Omar Jaluul, Wilson Jacob-Filho, Silvia Regina Dowgan Tesseroli de Siqueira
BACKGROUND: Oral infections affect the general health and overlap with chronic diseases due to infectious-immune mechanisms. On the other side, sensory abnormalities may be symptoms of this association. OBJECTIVE: To evaluate the prevalence of oral infections, comorbidities, health parameters and sensory abnormalities in elderly patients. METHODS: Thirty (30) elderly with mean age 70.4 yo, distributed according to ages were evaluated with a protocol that included demographics, comorbidities, medications, laboratory tests, blood pressure, heart rate, mini-mental state examination, clinical oral evaluation and systematized sensory testing (gustative, olfactory, thermal, mechanical and pain thresholds)...
July 1, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28728076/age-explains-limited-hip-extension-recovery-at-one-year-from-total-hip-arthroplasty
#7
Davide Mazzoli, Erika Giannotti, Maria Longhi, Paolo Prati, Stefano Masiero, Andrea Merlo
BACKGROUND: To investigate the dependency of the one-year recovery in gait after total hip arthroplasty on age and preoperative conditions. METHODS: Longitudinal retrospective study on 20 elderly patients with unilateral total hip arthroplasty consequent to hip osteoarthritis, assessed by gait analysis before surgery (T0), 2weeks (T1), 6 (T2) and 12months (T3) post-surgery. A set of variables assessing primary gait deviations and compensatory mechanisms were extracted from gait analysis data...
July 5, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28727853/independent-and-joint-effects-of-moderate-alcohol-consumption-and-smoking-on-the-risks-of-non-alcoholic-fatty-liver-disease-in-elderly-chinese-men
#8
Peiyi Liu, Yanyan Xu, Yuhan Tang, Min Du, Xiao Yu, Jian Sun, Lin Xiao, Meian He, Sheng Wei, Jing Yuan, Youjie Wang, Yuan Liang, Tangchun Wu, Xiaoping Miao, Ping Yao
BACKGROUND: Whether cigarette smoking and moderate drinking are associated with non-alcoholic fatty liver disease (NAFLD)has not been fully described. This study investigated the separate and joint effects of smoking and moderate drinking on Chinese men with NAFLD. METHODS: Across-sectional assay from DFTJ Cohort study was performed with a size of 9432 elderly Chinese men excluding excessive alcohol consumption (<210g/week). Fatty liver was diagnosed by standardized ultrasonographic inspection...
2017: PloS One
https://www.readbyqxmd.com/read/28727717/percutaneous-vertebroplasty-for-primary-non-hodgkin-s-lymphoma-of-the-thoracic-spine-case-report-and-review-of-the-literature
#9
Pu Jia, JinJun Li, Hao Chen, Li Bao, Fei Feng, Hai Tang
Primary non-Hodgkin's lymphoma of the vertebra is rare in the spine of the elderly. The clinical presentation and radiological features are unspecific, which make it more difficult for diagnosis. We report a case of a 79-year-old woman complaining of serious backache without any injury. The magnetic resonance imaging (MRI) showed invasion of the fifth thoracic vertebra with the posterior vertebral body wall defect. There was a high suspicion that the patient had a metastatic tumor of the vertebra. A percutaneous vertebroplasty was performed under fluoroscopic guidance, which was used to treat the osteoporotic vertebral compression fracture, vertebral metastases, verte-bral hemangioma, and multiple myeloma...
July 2017: Pain Physician
https://www.readbyqxmd.com/read/28727702/subcutaneous-injection-of-triamcinolone-and-lidocaine-to-prevent-postherpetic-neuralgia
#10
Jiaxiang Ni, Xiaoping Wang, Yuanzhang Tang, Liqiang Yang, Yuanjie Zeng, Yuna Guo
BACKGROUND: Herpes zoster (HZ) is associated with inflammation of the peripheral nerves, which is considered to be an important cause of postherpetic neuralgia (PHN). Interventions aimed at reducing this inflammation could prevent PHN. One option is the epidural administration of corticosteroid and local anesthetic. However, several authors have reported a risk of arachnoiditis with epidural corticosteroids. Subcutaneous injection in an outpatient setting is a safer option. However, there is limited evidence of the effectiveness of this alternative for preventing PHN...
July 2017: Pain Physician
https://www.readbyqxmd.com/read/28727639/effects-of-12-week-resistance-exercise-on-electroencephalogram-patterns-and-cognitive-function-in-the-elderly-with-mild-cognitive-impairment-a-randomized-controlled-trial
#11
Soon-Gook Hong, June-Hong Kim, Tae-Won Jun
OBJECTIVE: To investigate the effects of a 12-week resistance exercise program with an elastic band on electroencephalogram (EEG) patterns and cognitive function in elderly patients with mild cognitive impairment (MCI). DESIGN: Randomized controlled trial. SETTING: Community center. PARTICIPANTS: Twenty-two subjects with MCI and 25 healthy volunteer subjects were randomly assigned to 1 of 4 groups: subjects with MCI who undertook the exercise program (MCI-EX; n = 10), an MCI control group (MCI-Con; n = 12), a healthy volunteer exercise group (NG-EX; n = 12), and a healthy volunteer control group (NG-Con; n = 13)...
July 14, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/28727346/-doctor-physical-activity-at-my-age
#12
Martial Coutaz
Engaging in regular and appropriate physical activity confers health benefits at any age. For seniors, swapping the role of « sedentary » for « someone who's on the move » offers much more substantial benefits than any medication, and notably even starting at a dose of 10-15 minutes per day ! Any physician who cares for elderly patients must pursue the objective of encouraging physical activity that is integrated into daily life (e.g. walking, gardening, shopping). This article consists of a literature review concerning the evidence for the benefits of physical activity in seniors in terms of quality of life, longevity, maintenance of functional independence, and prevention of cognitive decline...
April 19, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28726972/consequences-of-warfarin-suspension-after-major-bleeding-in-very-elderly-patients-with-non-valvular-atrial-fibrillation
#13
Giacomo Zoppellaro, Serena Granziera, Giulia Bertozzo, Gentian Denas, Lucia Marigo, Florinda Petruzzellis, Seena Padayattil Jose, Katia Rossi, Giovanni Nante, Vittorio Pengo
No abstract text is available yet for this article.
July 20, 2017: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/28726502/spatial-reorientation-decline-in-aging-the-combination-of-geometry-and-landmarks
#14
Alessandro O Caffò, Antonella Lopez, Giuseppina Spano, Silvia Serino, Pietro Cipresso, Fabrizio Stasolla, Michelina Savino, Giulio E Lancioni, Giuseppe Riva, Andrea Bosco
OBJECTIVES: The study is focused on the assessment of reorientation skills in a sample of community-dwelling elderly people, manipulating landmarks and geometric (layout) information. METHOD: A neuropsychological assessment was administered to 286 elderly participants, divided into six groups (healthy controls, HC; four subgroups of participants with mild cognitive impairment, MCI; participants with probable dementia, Prob_D) and tested with the Virtual Reorientation Test (VReoT)...
July 20, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28726492/does-cognition-specific-computer-training-have-better-clinical-outcomes-than-non-specific-computer-training-a-single-blind-randomized-controlled-trial
#15
Ji-Hyuk Park, Jin-Hyuck Park
OBJECTIVE: The purpose of this study was to investigate differences between non-specific computer training (NCT) and cognition-specific computer training (CCT). DESIGN: Randomized controlled experimental study. SETTING: Local community welfare center. SUBJECTS: A total of 78 subjects with mild cognitive impairment (MCI) were randomly assigned to the NCT ( n = 39) or CCT group ( n = 39). INTERVENTION: The NCT group underwent NCT using Nintendo Wii for improving functional performance, while the CCT group underwent CCT using CoTras for improving function of the cognitive domain specifically...
July 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28726490/psychotropic-drug-prescription-for-nursing-home-residents-with-dementia-prevalence-and-associations-with-non-resident-related-factors
#16
Claudia H W Smeets, Debby L Gerritsen, Sytse U Zuidema, Steven Teerenstra, Klaas van der Spek, Martin Smalbrugge, Raymond T C M Koopmans
OBJECTIVES: To determine psychotropic drug prescription rates in nursing home residents with dementia and to identify associations with the so far understudied psychosocial non-resident-related factors. METHOD: A cross-sectional, observational, exploratory design as part of PROPER I (PRescription Optimization of Psychotropic drugs in Elderly nuRsing home patients with dementia). Participants were 559 nursing home residents with dementia, 25 physicians, and 112 nurses in the Netherlands...
July 20, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28726173/recurrent-glioblastomas-in-the-elderly-after-maximal-first-line-treatment-does-preserved-overall-condition-warrant-a-maximal-second-line-treatment
#17
Marc Zanello, Alexandre Roux, Renata Ursu, Sophie Peeters, Luc Bauchet, Georges Noel, Jacques Guyotat, Pierre-Jean Le Reste, Thierry Faillot, Fabien Litre, Nicolas Desse, Evelyne Emery, Antoine Petit, Johann Peltier, Jimmy Voirin, François Caire, Jean-Luc Barat, Jean-Rodolphe Vignes, Philippe Menei, Olivier Langlois, Edouard Dezamis, Antoine Carpentier, Phong Dam Hieu, Philippe Metellus, Johan Pallud
A growing literature supports maximal safe resection followed by standard combined chemoradiotherapy (i.e. maximal first-line therapy) for selected elderly glioblastoma patients. To assess the prognostic factors from recurrence in elderly glioblastoma patients treated by maximal safe resection followed by standard combined chemoradiotherapy as first-line therapy. Multicentric retrospective analysis comparing the prognosis and optimal oncological management of recurrent glioblastomas between 660 adult patients aged of < 70 years (standard group) and 117 patients aged of ≥70 years (elderly group) harboring a supratentorial glioblastoma treated by maximal first-line therapy...
July 19, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28726159/diagnosis-and-treatment-delays-among-elderly-breast-cancer-patients-with-pre-existing-mental-illness
#18
Kristy Iglay, Melissa L Santorelli, Kim M Hirshfield, Jill M Williams, George G Rhoads, Yong Lin, Kitaw Demissie
PURPOSE: This study aimed to compare diagnosis and treatment delays in elderly breast cancer patients with and without pre-existing mental illness. METHODS: A retrospective cohort study was conducted using the Surveillance, Epidemiology and End Results-Medicare data including 16,636 women 68+ years, who were diagnosed with stage I-IIIa breast cancer in the United States from 2005 to 2007. Mental illness was identified using International Classification of Diseases, Ninth Revision, Clinical Modification codes recorded on inpatient and outpatient claims during the 3 years prior to breast cancer diagnosis...
July 19, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28726047/dietary-acrylamide-exposure-was-associated-with-increased-cancer-mortality-in-chinese-elderly-men-and-women-a-11-year-prospective-study-of-mr-and-ms-os-hong-kong
#19
Zhao-Min Liu, Lap Ah Tse, Suzanne C Ho, Suyang Wu, Bailing Chen, Dicken Chan, Samuel Yeung-Shan Wong
AIM: Our study aims to investigate the association between dietary acrylamide exposure and cancer mortality among Chinese elderly. METHODS: A prospective cohort of 4000 elderly men and women aged 65 years and above (Mr. and Ms. OS Hong Kong study) was recruited from local communities from 2001 to 2003. Dietary exposure to acrylamide was evaluated at baseline based on a validated food frequency questionnaire and an acrylamide database from the 1st Hong Kong Total Diet Study...
July 19, 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/28725985/diversity-in-fall-characteristics-hampers-effective-prevention-the-precipitants-the-environment-the-fall-and-the-injury
#20
K M Sanders, K Lim, A L Stuart, A Macleod, D Scott, G C Nicholson, L Busija
Falls among the elderly are common and characteristics may differ between injurious and non-injurious falls. Among 887 older Australian women followed for 1.6 years, 32% fell annually. Only 8.5% resulted in fracture and/or hospital admission. The characteristics of those falls are indistinguishable from those not coming to medical attention. INTRODUCTION: The precipitants and environment of all falls occurring among a large cohort of older Caucasian women were categorised by injury status to determine if the characteristics differed between injurious and non-injurious falls...
July 19, 2017: Osteoporosis International
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