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https://www.readbyqxmd.com/read/28514355/-the-prevalence-of-tympanosclerosis-and-the-effectiveness-of-its-surgical-treatment
#1
E V Garov, N G Sidorina, E E Zagorskaya, P A Sudarev, A S Meparishvili
The objective of the present study was to characterize the epidemiological variants of tympanosclerosis and the effectiveness of the surgical treatment of the patients presenting with this condition. We have undertaken the analysis of the results of 1965 surgical interventions on the patients suffering from different forms of chronic otitis media (COM) performed during the period from 2009 till 2014 with a view to determining the frequency of tympanosclerosis (TSC). In 542 cases, it proved possible to evaluate the intraoperative findings, stages and methods of reconstructive surgery, the anatomical and functional outcomes and effectiveness of the intervention...
2017: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/28511400/a-case-report-of-a-giant-cholesteatoma
#2
Neelam Sood, Binit Kumar Khandelia, Gitanjali Bugnait
Cholesteatoma is a well demarcated, non-neoplastic, temporal bone cystic lesion with extensive keratinisation. Keratoma and epidermoid cyst are other possibly more accurate names suggested to describe the same. It can be classified as congenital or acquired. Its management is often complicated by its tendency to recidivism/recurrence. Long standing cholesteatomas can be a precursor for squamous cell carcinoma. We hereby present a case of giant cholesteatoma in a 45-year-old female with radiological involvement of the left temporal region, periauricular region and infratemporal fossa with lytic destruction of left middle ear ossicles, mastoid and squamous part of temporal bone with intracranial extension...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28504915/prevalence-of-os-styloideum-in-national-hockey-league-players
#3
Harry G Greditzer, Ian D Hutchinson, Christian S Geannette, Robert N Hotchkiss, Bryan T Kelly, Hollis G Potter
BACKGROUND: Os styloideum describes an accessory carpal ossicle between the trapezoid, the capitate, and the second and third metacarpals. Injuries to this tissue have been described as part of the carpal boss syndrome. While the etiology of os styloideum remains uncertain, it may represent a physiologic response to altered loading forces in the wrist, similar to the development of cam-type deformity in the hips of ice hockey players or the Bennett lesion in the shoulders of baseball pitchers...
May 1, 2017: Sports Health
https://www.readbyqxmd.com/read/28498081/finite-element-analysis-of-auditory-characteristics-in-patients-with-middle-ear-diseases
#4
Bo Tu, Xiaoping Li, Zhenhua Nie, Changzheng Shi, Hengguo Li
CONCLUSION: This study validates that a finite element model of the human ossicular chain and tympanic membrane can be used as an effective surgical assessment tool in clinics. OBJECTIVE: The present study was performed to investigate the application of a finite element model of ossicular chain and tympanic membrane for fabrication of individualized artificial ossicles. METHODS: Twenty patients (20 ears) who underwent surgery for middle ear disease (n = 20) and 10 healthy controls (10 ears) were enrolled in the hospital...
February 28, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28463590/systematic-review-of-ossicular-chain-anatomy-strategic-planning-for-development-of-novel-middle-ear-prostheses
#5
Brandon Kamrava, Pamela C Roehm
Objective To systematically review the anatomy of the ossicular chain. Data Sources Google Scholar, PubMed, and otologic textbooks. Review Methods A systematic literature search was performed on January 26, 2015. Search terms used to discover articles consisted of combinations of 2 keywords. One keyword from both groups was used: [ ossicular, ossicle, malleus, incus, stapes] and [ morphology, morphometric, anatomy, variation, physiology], yielding more than 50,000 hits. Articles were then screened by title and abstract if they did not contain information relevant to human ossicular chain anatomy...
April 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28440726/expression-of-c-type-lectin-receptor-mrna-in-chronic-otitis-media-with-cholesteatoma
#6
Sang Hoon Kim, Seung-Ho Han, Jae Yong Byun, Moon Suh Park, Young Il Kim, Seung Geun Yeo
CONCLUSIONS: The levels of expression of various C-type lectin receptors (CLRs) messenger ribo nucleic acids (mRNAs) were significantly higher in cholesteatomas than in normal skin, suggesting that these CLRs may be involved in the pathogenesis of cholesteatoma. OBJECTIVES: Altered expression of pattern recognition receptors may be associated with immune responses in patients with cholesteatoma. This study assessed the levels of expression of CLR mRNAs in normal skin and in cholesteatoma...
June 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28439694/modifications-to-a-3d-printed-temporal-bone-model-for-augmented-stapes-fixation-surgery-teaching
#7
Yann Nguyen, Elisabeth Mamelle, Daniele De Seta, Olivier Sterkers, Daniele Bernardeschi, Renato Torres
Functional outcomes and complications in otosclerosis surgery are governed by the surgeon's experience. Thus, teaching the procedure to residents to guide them through the learning process as quickly as possible is challenging. Artificial 3D-printed temporal bones are replacing cadaver specimens in many institutions to learn mastoidectomy, but these are not suitable for middle ear surgery training. The goal of this work was to adapt such an artificial temporal bone to aid the teaching of otosclerosis surgery and to evaluate this tool...
April 24, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28420248/creating-an-optimal-3d-printed-model-for-temporal-bone-dissection-training
#8
Kuniyuki Takahashi, Yuka Morita, Shinsuke Ohshima, Shuji Izumi, Yamato Kubota, Yutaka Yamamoto, Sugata Takahashi, Arata Horii
OBJECTIVE: Making a 3-dimensional (3D) temporal bone model is simple using a plaster powder bed and an inkjet printer. However, it is difficult to reproduce air-containing spaces and precise middle ear structures. The objective of this study was to overcome these problems and create a temporal bone model that would be useful both as a training tool and for preoperative simulation. METHODS: Drainage holes were made to remove excess materials from air-containing spaces, ossicle ligaments were manually changed to bony structures, and small and/or soft tissue structures were colored differently while designing the 3D models...
April 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28390446/genetic-influence-on-accessory-navicular-bone-in-the-foot-a-korean-twin-and-family-study
#9
In Yae Cheong, Hyo Jeong Kang, Hyeonyoung Ko, Joohon Sung, Yun-Mi Song, Ji Hye Hwang
An accessory navicular bone (AN) is the most common accessory ossicle in the foot. The presence of an AN bone can trigger various foot problems, such as posterior tibial tendon pathology, flattening of the medial longitudinal arch, and medial foot pain. Despite the clinical influence of presence of an AN in foot disease, the research regarding its inheritance is still insufficient. A total of 135 pairs of monozygotic (MZ) twins, 25 pairs of dizygotic (DZ) twins, and 676 singletons from families were enrolled in order to estimate genetic influences on AN...
April 9, 2017: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/28387614/reduction-of-atlantoaxial-dislocation-prevented-by-pathological-position-of-the-transverse-ligament-in-fixed-irreducible-os-odontoideum-operative-illustrations-and-radiographic-correlates-in-41-patients
#10
Brian J Dlouhy, Bruno A Policeni, Arnold H Menezes
OBJECTIVE Os odontoideum (OO) is a craniovertebral junction (CVJ) abnormality in which an ossicle (small bone) is cranial to a hypoplastic dens by a variable gap. This abnormality can result in instability, which may be reducible or irreducible. What leads to irreducibility in OO is unclear. Therefore, the authors sought to better understand the causes of irreducibility in OO. METHODS A retrospective review was conducted, which identified more than 200 patients who had undergone surgical treatment for OO between 1978 and 2015 at the University of Iowa Hospitals and Clinics...
April 7, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28320600/tympanometry-and-isolated-fracture-of-the-stapes
#11
C Aussedat, C Bobiller, K Gaillot, E Lescanne, D Bakhos
INTRODUCTION: Temporal bone fractures are frequently associated with ossicular dislocations or fractures, most commonly involving the incus. To our knowledge, isolated fracture of the posterior crus of the stapes has not been previously reported. CASE REPORT: A 20-year-old man consulted for persistent left hypoacusis several months after a head injury. Initial computed tomography of the temporal bone showed a simple temporal bone fracture with no other associated abnormalities...
March 17, 2017: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/28295608/incidence-and-anatomical-variations-of-accessory-navicular-bone-in-patients-with-foot-pain-a-retrospective-radiographic-analysis
#12
Heba Kalbouneh, Omar Alajoulin, Mohammad Alsalem, Noor Humoud, Jamil Shawaqfeh, Mohammad Alkhoujah, Hana Abu-Hassan, Waleed Mahafza, Darwish Badran
The accessory navicular (AN) is an accessory ossicle anatomically located on the medial side of the foot, proximal to the navicular and continuous with the tibialis posterior tendon. It is occasionally a source of pain and local tenderness. Knowledge of the AN and its morphological variations can help identify the source of a patient's symptoms and prevent misinterpreting them as fractures. Foot radiographs from 1,240 patients who presented in two centers with chronic foot pain, or persistent pain developed after trauma, were retrospectively reviewed to determine the incidence and variations of the AN in relation to gender...
March 13, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28292847/human-umbilical-cord-blood-borne-fibroblasts-contain-marrow-niche-precursors-that-form-a-bone-marrow-organoid-in-vivo
#13
Alice Pievani, Benedetto Sacchetti, Alessandro Corsi, Benedetta Rambaldi, Samantha Donsante, Valeria Scagliotti, Patrizia Vergani, Cristina Remoli, Andrea Biondi, Pamela G Robey, Mara Riminucci, Marta Serafini
Human umbilical cord blood (CB) has attracted much attention as a reservoir for functional hematopoietic stem and progenitor cells, and, recently, as a source of blood-borne fibroblasts (CB-BFs). Previously, we demonstrated that bone marrow stromal cell (BMSC) and CB-BF pellet cultures make cartilage in vitro Furthermore, upon in vivo transplantation, BMSC pellets remodelled into miniature bone/marrow organoids. Using this in vivo model, we asked whether CB-BF populations that express characteristics of the hematopoietic stem cell (HSC) niche contain precursors that reform the niche...
March 15, 2017: Development
https://www.readbyqxmd.com/read/28292001/-implantable-bone-conduction-and-active-middle-ear-devices
#14
Markus Pirlich, Andreas Dietz, Sylvia Meuret, Mathias Hofer
In case of audiological and/or anatomical limitations in the provision of conventional hearing aids, semi- or fully-implantable hearing systems represent a modern therapy alternative. These hearing systems are divided according to their mode of action into active middle ear implants when stimulating the auditory ossicles or the round window, into bone conduction devices while stimulating the skull directly, into cochlear implants with direct acoustic stimulation to the cochlea with its auditory nerve and finally into auditory brainstem implants by bridging the peripheral auditory structures...
February 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/28273957/morphological-variations-of-middle-ear-ossicles-and-its-clinical-implications
#15
Ritaban Saha, Phalguni Srimani, Ardhendu Mazumdar, Sibani Mazumdar
INTRODUCTION: The middle ear ossicles form a semi rigid chain in the middle of the ear for conduction and amplification of sound waves from the tympanic membrane to the inner ear. Although, our knowledge of the ear ossicles dates back to the 15(th) century, and various studies have been carried out on their morphometry, morphology, anomalies, embryology, function and structure throughout the world, information about the morphology of middle ear ossicles is meagre in Indian subjects. AIM: To find out the morphological variations of middle ear ossicles of right and left sides...
January 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28255943/posterior-tibial-tendon-impingement-due-to-os-subtibiale-a-case-report-and-up-to-date-review
#16
Adil Turan, Ozkan Kose, Baver Acar, Melih Unal
Os subtibiale is a rare accessory ossicle located at the tip of the medial malleolus. Although this small ossicle usually has no clinical significance, in some cases it may be a source of ankle pain. Symptomatic os subtibiale is an extremely rare diagnosis, and few cases have been reported to date. The case presented is of a 35-year-old female patient with symptomatic os subtibiale, with a discussion of the diagnosis, clinical findings, and treatment options.
March 2, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28255483/stenosing-tenosynovitis-of-the-flexor-hallucis-longus-tendon-associated-with-the-plantar-capsular-accessory-ossicle-at-the-interphalangeal-joint-of-the-great-toe
#17
Song Ho Chang, Takumi Matsumoto, Masashi Naito, Sakae Tanaka
This report presents a case of stenosing tenosynovitis of the flexor hallucis longus tendon associated with the plantar capsular accessory ossicle at the interphalangeal joint of the great toe, which was confirmed by intraoperative observation and was successfully treated with surgical resection of the ossicle. As the plantar capsular accessory ossicle was not visible radiographically due to the lack of ossification, ultrasonography was helpful for diagnosing this disorder.
2017: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/28196691/healing-of-a-large-long-bone-defect-through-serum-free-in%C3%A2-vitro-priming-of%C3%A2-human-periosteum-derived-cells
#18
Johanna Bolander, Wei Ji, Jeroen Leijten, Liliana Moreira Teixeira, Veerle Bloemen, Dennis Lambrechts, Malay Chaklader, Frank P Luyten
Clinical translation of cell-based strategies for regenerative medicine demands predictable in vivo performance where the use of sera during in vitro preparation inherently limits the efficacy and reproducibility. Here, we present a bioinspired approach by serum-free pre-conditioning of human periosteum-derived cells, followed by their assembly into microaggregates simultaneously primed with bone morphogenetic protein 2 (BMP-2). Pre-conditioning resulted in a more potent progenitor cell population, while aggregation induced osteochondrogenic differentiation, further enhanced by BMP-2 stimulation...
March 14, 2017: Stem Cell Reports
https://www.readbyqxmd.com/read/28187565/a-taxonomic-review-of-the-genus-astrohelix-d%C3%A3-derlein-1930-including-the%C3%A2-synonymy-of-the-subgenus-i-asteroporpa-i-i-astromoana-i-baker-1980-to-i-astrohelix-i
#19
Masanori Okanishi
The holotypes of Astrohelix bellator bellator and Astrohelix bellator paucidens (Echinodermata: Ophiuroidea: Euryalida: Gorgonocephalidae) are redescribed. Based on these observations Asteroporpa (Astromoana) with Astrohelix is proposed. With the elevation of two subspecies of Asteroporpa (Astrohelix) bellator bellator and A. (Astrohelix) bellator paucidens to species level, A. (Astrohelix) comprises six species, A. (Astrohelix) bellator, A. (Astrohelix) indicus, A. (Astrohelix) koyoae, A. (Astrohelix) muricatopatella, A...
February 6, 2017: Zootaxa
https://www.readbyqxmd.com/read/28182695/two-three-loci-control-scleral-ossicle-formation-via-epistasis-in-the-cavefish-astyanax-mexicanus
#20
Anastasia Lyon, Amanda K Powers, Joshua B Gross, Kelly E O'Quin
The sclera is the protective outer layer of the eye. In fishes, birds, and reptiles, the sclera may be reinforced with additional bony elements called scleral ossicles. Teleost fish vary in the number and size of scleral ossicles; however, the genetic mechanisms responsible for this variation remain poorly understood. In this study, we examine the inheritance of scleral ossicles in the Mexican tetra, Astyanax mexicanus, which exhibits both a cave morph and a surface fish morph. As these morphs and their hybrids collectively exhibit zero, one, and two scleral ossicles, they represent a microcosm of teleost scleral ossicle diversity...
2017: PloS One
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