keyword
MENU ▼
Read by QxMD icon Read
search

Q.I.

keyword
https://www.readbyqxmd.com/read/29028978/comparative-epidemiology-and-outcomes-of-hiv-non-hiv-non-transplant-and-organ-transplant-associated-cryptococcosis-a-population-based-study
#1
I A George, A Spec, W G Powderly, C A Q Santos
In this population-based study in the contemporary era in the United States, the proportion of HIV-negative patients with cryptococcosis is approaching that in HIV-infected patients. Cryptococossis is associated with higher mortality in HIV-negative patients (including organ transplant recipients).
October 4, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29027372/full-genome-sequence-of-porcine-circovirus-type-3-recovered-from-serum-of-sows-with-stillbirths-in-brazil
#2
C Tochetto, D A Lima, A P M Varela, M R Loiko, W P Paim, C M Scheffer, J I Herpich, C Cerva, C Schmitd, S P Cibulski, A C Santos, F Q Mayer, P M Roehe
Two full-genome sequences of porcine circovirus type 3 (PCV3) are reported. The genomes were recovered from pooled serum samples from sows who had just delivered litters with variable numbers of stillbirths. The two circular genomes (PCV3-BR/RS/6 and PCV3-BR/RS/8) are 2,000 nucleotides long and contain two open reading frames (ORFs) oriented in opposite directions that encode the putative capsid (Cap) and replicase (Rep) proteins. The intergenic region contains a stem-loop motif, as reported for other circoviruses...
October 12, 2017: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/29026923/nonhuman-primate-models-for-studies-of-aids-virus-persistence-during-suppressive-combination-antiretroviral-therapy
#3
Gregory Q Del Prete, Jeffrey D Lifson
Nonhuman primate (NHP) models of AIDS represent a potentially powerful component of the effort to understand in vivo sources of AIDS virus that persist in the setting of suppressive combination antiretroviral therapy (cART) and to develop and evaluate novel strategies for more definitive treatment of HIV infection (i.e., viral eradication "cure", or sustained off-cART remission). Multiple different NHP models are available, each characterized by a particular NHP species, infecting virus, and cART regimen, and each with a distinct capacity to recapitulate different aspects of HIV infection...
October 13, 2017: Current Topics in Microbiology and Immunology
https://www.readbyqxmd.com/read/29026432/timely-initiation-of-breastfeeding-and-its-association-with-birth-place-in-ethiopia-a-systematic-review-and-meta-analysis
#4
REVIEW
Animut Alebel, Getiye Dejenu, Getachew Mullu, Nurilign Abebe, Tenaw Gualu, Setegn Eshetie
BACKGROUND: Timely initiation of breastfeeding is defined as putting the newborn to the breast within 1 h of birth. In Ethiopia, different studies have been conducted to assess the prevalence of timely initiation of breastfeeding and associated factors. The findings of these studies were inconsistent and characterized by great variability. Therefore, the aim of this systematic review and meta-analysis was to estimate the pooled prevalence of timely initiation of breastfeeding and its association with birth place in Ethiopia using the available studies...
2017: International Breastfeeding Journal
https://www.readbyqxmd.com/read/29025232/commentary-on-autologous-adipose-derived-tissue-matrix-parts-i-and-ii
#5
Lee L Q Pu
No abstract text is available yet for this article.
October 1, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29024923/a-ghep-isfg-collaborative-study-on-the-genetic-variation-of-38-autosomal-indels-for-human-identification-in-different-continental-populations
#6
R Pereira, C Alves, M Aler, A Amorim, C Arévalo, E Betancor, D Braganholi, M L Bravo, P Brito, J J Builes, G Burgos, E F Carvalho, A Castillo, C I Catanesi, R M B Cicarelli, P Coufalova, P Dario, M E D'Amato, S Davison, J Ferragut, M Fondevila, S Furfuro, O García, A Gaviria, I Gomes, E González, A Gonzalez-Liñan, T E Gross, A Hernández, Q Huang, S Jiménez, L F Jobim, A M López-Parra, M Marino, S Marques, G Martínez-Cortés, V Masciovecchio, D Parra, G Penacino, M F Pinheiro, M J Porto, Y Posada, C Restrepo, T Ribeiro, L Rubio, A Sala, A Santurtún, L S Solís, L Souto, E Streitemberger, A Torres, C Vilela-Lamego, J J Yunis, I Yurrebaso, L Gusmão
A collaborative effort was carried out by the Spanish and Portuguese Speaking Working Group of the International Society for Forensic Genetics (GHEP-ISFG) to promote knowledge exchange between associate laboratories interested in the implementation of indel-based methodologies and build allele frequency databases of 38 indels for forensic applications. These databases include populations from different countries that are relevant for identification and kinship investigations undertaken by the participating laboratories...
September 22, 2017: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/29024507/dietary-patterns-and-semen-quality-a-systematic-review-and-meta-analysis-of-observational-studies
#7
REVIEW
A Arab, N Rafie, M Mansourian, M Miraghajani, H Hajianfar
A number of studies have examined the association between dietary patterns and semen quality, but the findings have been inconclusive. Herein, we conducted a systematic review and meta-analysis of observational studies to assess the association between dietary patterns and semen quality. PubMed, Cochrane library, Science direct, Scopus, Google Scholar, and ISI web of science databases were searched up to August 2016 for observational studies assessing the association between common dietary patterns and sperm quality markers...
October 12, 2017: Andrology
https://www.readbyqxmd.com/read/29023824/cholangiocyte-autophagy-contributes-to-hepatic-cystogenesis-in-polycystic-liver-disease-and-represents-a-potential-therapeutic-target
#8
Anatoliy I Masyuk, Tatyana V Masyuk, Maria J Lorenzo Pisarello, Jingyi Francess Ding, Lorena Loarca, Bing Q Huang, Nicholas F LaRusso
Polycystic liver disease (PLD) is a group of genetic disorders with limited treatment and significant morbidity. Hepatic cysts arise from cholangiocytes exhibiting a hyperproliferative phenotype. Considering that hyperproliferation of many cell types is associated with alterations in autophagy, we hypothesized that autophagy is altered in PLD cholangiocytes, contributes to hepatic cystogenesis, and might represent a potential therapeutic target. We employed Functional Pathway Cluster Analysis (FPCA) and NextGen Sequencing (NGS), transmission electron microscopy, immunofluorescence confocal microscopy, and western blotting to assess autophagy in human and rodent PLD cholangiocytes...
October 10, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/29023546/steroid-hormones-and-psychological-responses-to-soccer-matches-insights-from-a-systematic-review-and-meta-analysis
#9
Maamer Slimani, Julien S Baker, Foued Cheour, Lee Taylor, Nicola Luigi Bragazzi
The present systematic review and meta-analysis aimed to assess the perturbations in hormonal and psychological homeostasis in response to soccer match-play. These perturbations were explored according to match outcome (i.e., win versus loss), gender, type of contest (i.e., competitive versus non-competitive fixtures) and competitive level (i.e., novice versus high-level). The review was conducted according to the Population/Intervention or Exposure/Comparison/Outcome(s) (PICO) criteria and the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines...
2017: PloS One
https://www.readbyqxmd.com/read/29023119/how-does-the-central-atom-substitution-impact-the-properties-of-criegee-intermediate-insights-from-multi-reference-calculations
#10
Tarek Trabelsi, Manoj Kumar, Joseph S Francisco
Complete active space self-consistent field (CASSCF) and multi-reference configuration interaction (MRCI)-based multi-reference calculations have been performed to better understand the ground state properties and the photodis-sociation mechanism of SiH2OO, a silicon analogue of the parent Criegee intermediate, CH2OO. The CASSCF/aug-cc-pV(Q+d)Z results suggest that the ground state of SiH2OO is severely multi-reference in nature, implying that mon-oreference methods such as density functional theory or coupled cluster are incapable of accurately describing this sys-tem...
October 12, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29022775/arthroscopic-versus-open-excision-of-dorsal-ganglion-cysts-a-systematic-review
#11
Catherine Crawford, Aakash Keswani, Andrew J Lovy, Isaiah Levy, Kristina Lutz, Jaehon Kim, Michael Hausman
We conducted a systematic review comparing recurrence and complication rate following open versus arthroscopic excision of ganglion cysts. Sixteen full-text articles were included. The pooled recurrence rate of open excision was 20% (range: 5.6-40.7%) with Q value of 27 and I(2) of 82%. The pooled recurrence rate of arthroscopic excision was 9% (range: 0-17%) with Q value of 10 and I(2) of 2%. Eleven of 16 studies were low quality or had a high risk of bias; however, excluding low quality studies or those with high risk of bias produced similar recurrence rates in arthroscopic and open excision (7...
January 1, 2017: Journal of Hand Surgery, European Volume
https://www.readbyqxmd.com/read/29022068/esophagectomy-for-end-stage-achalasia-systematic-review-and-meta-analysis
#12
REVIEW
Alberto Aiolfi, Emanuele Asti, Gianluca Bonitta, Luigi Bonavina
BACKGROUND: Indications for surgery and clinical outcomes of esophagectomy in the management of end-stage achalasia are not clearly defined. The aim of this systematic review and meta-analysis was to provide evidence-based information to help in the decision-making and in the choice of surgical technique. METHODS: An extensive literature search was conducted to identify all reports on esophagectomy for end-stage achalasia patients over the past three decades. MEDLINE, Embase and Cochrane databases were thoroughly consulted matching the terms "achalasia," "end-stage achalasia," "esophagectomy" and "esophageal resection" with "AND" and "OR...
October 11, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29021588/robust-fusion-of-diffusion-mri-data-for-template-construction
#13
Zhanlong Yang, Geng Chen, Dinggang Shen, Pew-Thian Yap
Construction of brain templates is generally carried out using a two-step procedure involving registering a population of images to a common space and then fusing the aligned images to form a template. In practice, image registration is not perfect and simple averaging of the images will blur structures and cause artifacts. In diffusion MRI, this is further complicated by intra-voxel inter-subject differences in fiber orientation, fiber configuration, anisotropy, and diffusivity. In this paper, we propose a method to improve the construction of diffusion MRI templates in light of inter-subject differences...
October 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29021401/rnaseq-analysis-of-differentiated-keratinocytes-reveals-a-massive-response-to-late-events-during-human-papillomavirus-type-16-infection-including-loss-of-epithelial-barrier-function
#14
T Klymenko, Q Gu, I Herbert, A Stevenson, V Iliev, G Watkins, C Pollock, R Bhatia, K Cuschieri, P Herzyk, D Gatherer, S V Graham
The human papillomavirus (HPV) replication cycle is tightly linked to epithelial cell differentiation. To examine HPV-associated changes in the keratinocyte transcriptome, RNAs isolated from undifferentiated and differentiated cell populations of normal, spontaneously immortalised, keratinocytes (NIKS), and NIKS stably transfected with HPV16 episomal genomes (NIKS16), were compared using RNASeq. HPV16 infection altered expression of 2862 cellular genes. Next, to elucidate the role of keratinocyte gene expression in late events during the viral life cycle, RNASeq was carried out on triplicate differentiated populations of NIKS (uninfected) and NIKS16 (infected)...
October 11, 2017: Journal of Virology
https://www.readbyqxmd.com/read/29020939/a-transcriptomic-approach-to-study-the-effect-of-long-term-starvation-and-diet-composition-on-the-expression-of-mitochondrial-oxidative-phosphorylation-genes-in-gilthead-sea-bream-sparus-aurata
#15
Jonás I Silva-Marrero, Alberto Sáez, Albert Caballero-Solares, Ivan Viegas, María Pilar Almajano, Felipe Fernández, Isabel V Baanante, Isidoro Metón
BACKGROUND: The impact of nutritional status and diet composition on mitochondrial oxidative phosphorylation (OXPHOS) in fish remains largely unknown. To identify biomarkers of interest in nutritional studies, herein we obtained a deep-coverage transcriptome by 454 pyrosequencing of liver and skeletal muscle cDNA normalised libraries from long-term starved gilthead sea bream (Sparus aurata) and fish fed different diets. RESULTS: After clean-up of high-throughput deep sequencing reads, 699,991 and 555,031 high-quality reads allowed de novo assembly of liver and skeletal muscle sequences, respectively (average length: 374 and 441 bp; total megabases: 262 and 245 Mbp)...
October 11, 2017: BMC Genomics
https://www.readbyqxmd.com/read/29019965/molecular-cloning-recombinant-expression-and-antifungal-activity-of-bncpi-a-cystatin-in-ramie-boehmeria-nivea-l
#16
Yongting Yu, Gang Zhang, Zhimin Li, Yi Cheng, Chunsheng Gao, Liangbin Zeng, Jia Chen, Li Yan, Xiangping Sun, Litao Guo, Zhun Yan
Phytocystatins play multiple roles in plant growth, development and resistance to pests and other environmental stresses. A ramie (Boehmeria nivea L.) phytocystatin gene, designated as BnCPI, was isolated from a ramie cDNA library and its full-length cDNA was obtained by rapid amplification of cDNA ends (RACE). The full-length cDNA sequence (691 bp) consisted of a 303 bp open reading frame (ORF) encoding a protein of 100 amino acids with deduced molecular mass of 11.06 kDa and a theoretical isoelectric point (pI) of 6...
October 11, 2017: Genes
https://www.readbyqxmd.com/read/29017403/protective-effect-of-zizyphus-lotus-jujube-fruits-against-cypermethrin-induced-oxidative-stress-and-neurotoxicity-in-mice
#17
Khazri Abdelhafidh, Lazher Mhadhbi, Ali Mezni, Sellami Badreddine, Hamouda Beyrem, Ezzeddine Mahmoudi
CONTEXT: Cypermethrin (CYP) is a synthetic pyrethroid insecticide used worldwide in agriculture, home pest control. The toxicity of CYP is well studied in many organisms Objective: The aim of present study was to investigate the protective effect of Zizyphus lotus (Zizyp) fruit against neurotoxicity and oxidative stress induced by CYP in mice. MATERIALS AND METHODS: Mice were divided into four groups of six each: groups I and II were used as control and CYP control (20mg/kg body weight)...
October 11, 2017: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
https://www.readbyqxmd.com/read/29017331/distinct-prognostic-roles-of-hspb1-expression-in-non-small-cell-lung-cancer
#18
Z C Huang, H Li, Z Q Sun, J Zheng, R K Zhao, J Chen, S G Sun, C J Wu
Distinct prognostic roles of HSPB1 expression in non-small cell lung cancer Lung cancer is the leading cause of cancer morbidity and mortality around world. Heat shock protein beta-1 (HSPB1) expression is aberrantly increased in non-small cell lung cancer (NSCLC) patients. However, the roles of HSPB1 expression in the prognosis of NSCLC are still elusive. In this study, we investigated the prognostic roles of HSPB1 in NSCLC by using "The Kaplan-Meier plotter" (KM plotter) database. Our data indicated that HSPB1 mRNA low expression was correlated to better overall survival (OS) for all NSCLC patients, hazard ratio (HR) 1...
October 11, 2017: Neoplasma
https://www.readbyqxmd.com/read/29017321/terminal-electron-proton-transfer-dynamics-in-the-quinone-reduction-of-respiratory-complex%C3%A2-i
#19
Ana Patricia Gámiz-Hernández, Alexander Jussupow, Mikael P Johansson, Ville R I Kaila
Complex I functions as a redox-driven proton pump in aerobic respiratory chains. By reducing quinone (Q), complex I employs the free energy released in the process to thermodynamically drive proton pumping across its membrane domain. The initial Q reduction step plays a central role in activating the proton pumping machinery. In order to probe the energetics, dynamics, and molecular mechanism for the proton-coupled electron transfer (PCET) process linked to the Q reduction, we employ here multi-scale quantum and classical molecular simulations...
October 10, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29016887/phase-i-ii-trial-of-vorinostat-combined-with-temozolomide-and-radiation-therapy-for-newly-diagnosed-glioblastoma-final-results-of-alliance-n0874-abtc-02
#20
Evanthia Galanis, S Keith Anderson, C Ryan Miller, Jann N Sarkaria, Kurt Jaeckle, Jan C Buckner, Keith L Ligon, Karla V Ballman, Dennis F Moore, Michael Nebozhyn, Andrey Loboda, David Schiff, Manmeet Singh Ahluwalia, Eudocia Q Lee, Elizabeth R Gerstner, Glenn J Lesser, Michael Prados, Stuart A Grossman, Jane Cerhan, Caterina Giannini, Patrick Y Wen
Background: Vorinostat, a histone deacetylase inhibitor, has shown radiosensitizing properties in preclinical studies. This open-label, single-arm trial evaluated the maximum tolerated dose (MTD; phase I) and efficacy (phase II) of vorinostat combined with standard chemoradiation in newly diagnosed glioblastoma. Methods: Patients received oral vorinostat (300 or 400 mg/day) on days 1-5 weekly during temozolomide chemoradiation. Following a 4- to 6-week rest, patients received up to 12 cycles of standard adjuvant temozolomide and vorinostat (400 mg/day) on days 1-7 and 15-21 of each 28-day cycle...
August 22, 2017: Neuro-oncology
keyword
keyword
65861
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"