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Combat ultrasound

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https://www.readbyqxmd.com/read/28366540/valproate-induced-hepatic-steatosis-by-enhanced-fatty-acid-uptake-and-triglyceride-synthesis
#1
Xupeng Bai, Weipeng Hong, Peiheng Cai, Yibei Chen, Chuncao Xu, Di Cao, Weibang Yu, Zhongxiang Zhao, Min Huang, Jing Jin
Steatosis is the characteristic type of VPA-induced hepatotoxicity and may result in life-threatening hepatic lesion. Approximately 61% of patients treated with VPA have been diagnosed with hepatic steatosis through ultrasound examination. However, the mechanisms underlying VPA-induced intracellular fat accumulation are not yet fully understood. Here we demonstrated the involvement of fatty acid uptake and lipogenesis in VPA-induced hepatic steatosis in vitro and in vivo by using quantitative real-time PCR (qRT-PCR) analysis, western blotting analysis, fatty acid uptake assays, Nile Red staining assays, and Oil Red O staining assays...
March 31, 2017: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/28356203/variation-in-patients-travel-times-among-imaging-examination-types-at-a-large-academic-health-system
#2
Andrew B Rosenkrantz, Yu Liang, Richard Duszak, Michael P Recht
RATIONALE AND OBJECTIVES: Patients' willingness to travel farther distances for certain imaging services may reflect their perceptions of the degree of differentiation of such services. We compare patients' travel times for a range of imaging examinations performed across a large academic health system. MATERIALS AND METHODS: We searched the NYU Langone Medical Center Enterprise Data Warehouse to identify 442,990 adult outpatient imaging examinations performed over a recent 3...
March 27, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28285473/a-modern-case-series-of-resuscitative-endovascular-balloon-occlusion-of-the-aorta-reboa-in-an-out-of-hospital-combat-casualty-care-setting
#3
Justin D Manley, Benjamin J Mitchell, Joseph J DuBose, Todd E Rasmussen
BACKGROUND: Resuscitative endovascular balloon occlusion of the aorta (REBOA) is used to mitigate bleeding and sustain central aortic pressure in the setting of shock. The ER-REBOA™ catheter is a new REBOA technology, previously reported only in the setting of civilian trauma and injury care. The use of REBOA in an out-of-hospital setting has not been reported, to our knowledge. METHODS: We present a case series of wartime injured patients cared for by a US Air Force Special Operations Surgical Team at an austere location fewer than 3km (5-10 minutes' transport) from point of injury and 2 hours from the next highest environment of care-a Role 2 equivalent...
2017: Journal of Special Operations Medicine: a Peer Reviewed Journal for SOF Medical Professionals
https://www.readbyqxmd.com/read/27991697/materials-chemistry-of-nanoultrasonic-biomedicine
#4
Hailin Tang, Yuanyi Zheng, Yu Chen
As a special cross-disciplinary research frontier, nanoultrasonic biomedicine refers to the design and synthesis of nanomaterials to solve some critical issues of ultrasound (US)-based biomedicine. The concept of nanoultrasonic biomedicine can also overcome the drawbacks of traditional microbubbles and promote the generation of novel US-based contrast agents or synergistic agents for US theranostics. Here, we discuss the recent developments of material chemistry in advancing the nanoultrasonic biomedicine for diverse US-based bio-applications...
December 19, 2016: Advanced Materials
https://www.readbyqxmd.com/read/27908581/sonodynamic-inactivation-of-gram-positive-and-gram-negative-bacteria-using-a-rose-bengal-antimicrobial-peptide-conjugate
#5
David Costley, Heather Nesbitt, Nigel Ternan, James Dooley, Ying-Ying Huang, Michael R Hamblin, Anthony P McHale, John F Callan
Combating antimicrobial resistance is one of the most serious public health challenges facing society today. The development of new antibiotics or alternative techniques that can help combat antimicrobial resistance is being prioritised by many governments and stakeholders across the globe. Antimicrobial photodynamic therapy is one such technique that has received considerable attention but is limited by the inability of light to penetrate through human tissue, reducing its effectiveness when used to treat deep-seated infections...
January 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/27647603/the-effect-of-thumb-splinting-on-thenar-muscles-atrophy-pain-and-function-in-subjects-with-thumb-carpometacarpal-joint-osteoarthritis
#6
Mokhtar Arazpour, Mohaddeseh Soflaei, Monireh Ahmadi Bani, Seyed Pezhman Madani, Mahsa Sattari, Akbar Biglarian, Zahra Mosallanezhad
BACKGROUND: When the first carpometacarpal joint of the wrist is immobilized using an orthosis to combat the effects of osteoarthritis, atrophy of the thenar muscles may occur. OBJECTIVES: The aim of this study was to evaluate the thenar muscle diameter and cross-sectional area, joint function, and pain, before and after being supplied with an orthosis in patients with grades 1 and 2 carpometacarpal osteoarthritis compared to a control group. STUDY DESIGN: Randomized clinical trial...
September 19, 2016: Prosthetics and Orthotics International
https://www.readbyqxmd.com/read/27540480/adjunctive-intra-coronary-imaging-for-the-assessment-of-coronary-artery-disease
#7
Nikunj Shah, Bassey Ussen, Michael Mahmoudi
Atherosclerotic coronary artery disease remains a leading cause of worldwide morbidity and mortality. Invasive angiography currently remains the gold standard method of diagnosing and treating coronary disease; however, more sophisticated adjunctive interventional technologies have been developed to combat the inter and intra-observer variability frequently encountered in the assessment of lesion severity. Intravascular imaging now plays a key role in optimising percutaneous coronary interventions and provides invaluable information as part of the interventional cardiologist's diagnostic arsenal...
January 2016: JRSM Cardiovascular Disease
https://www.readbyqxmd.com/read/27532142/the-incidence-of-thromboembolism-formation-following-the-use-of-recombinant-factor-viia-in-patients-suffering-from-blunt-force-trauma-compared-with-penetrating-trauma-a-systematic-review
#8
Raymond Devlin, Laura Bonanno, Jennifer Badeaux
BACKGROUND: Rapid replacement of blood loss is critical in patients suffering from traumatic hemorrhage. When the availability of blood products is limited, certain interventions have shown promise in conserving blood supplies. Recombinant factor (rF) VIIa has been administered, as an off-label use, to assist in controlling hemorrhage in trauma patients. Although rFVIIa has a tendency to remain localized to areas of vascular insult, there may be an increase in thromboembolism formation when patients suffer multiple sites of injury as seen in blunt force trauma...
March 2016: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/27404048/engineered-biomaterial-and-biophysical-stimulation-as-combinatorial-strategies-to-address-prosthetic-infection-by-pathogenic-bacteria
#9
Sunil Kumar Boda, Bikramjit Basu
A plethora of antimicrobial strategies are being developed to address prosthetic infection. The currently available methods for implant infection treatment include the use of antibiotics and revision surgery. Among the bacterial strains, Staphylococcus species pose significant challenges particularly, with regard to hospital acquired infections. In order to combat such life threatening infectious diseases, researchers have developed implantable biomaterials incorporating nanoparticles, antimicrobial reinforcements, surface coatings, slippery/non-adhesive and contact killing surfaces...
July 12, 2016: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/27299856/high-resolution-ultrasound-in-combat-related-peripheral-nerve-injuries
#10
Jonathan K Smith, Matthew E Miller, Craig G Carroll, Walter J Faillace, Leon J Nesti, Christina M Cawley, Mark E Landau
INTRODUCTION: Peripheral nerve injuries (PNI) sustained in combat are typically severe and are frequently associated with marked soft tissue damage, anatomic distortion, and retained metallic fragments. These features complicate clinical and electrodiagnostic assessment and may preclude MRI. METHODS: We describe 4 cases of military personnel who sustained high-velocity gunshot wounds or blasts with metal fragment injuries in which high resolution peripheral nerve ultrasound (US) proved beneficial...
December 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27295817/innovative-program-targets-five-common-pain-syndromes-with-non-opioid-alternatives
#11
(no author information available yet)
To combat the prescription opioid problem, St. Joseph's Healthcare System in Paterson, NJ, has developed a new program that gives providers options they can use to effectively alleviate pain without resorting to highly addictive medication. Launched in January 2016 in the ED at St. Joseph's Regional Medical Center (SJRMC), the Alternatives to Opioids (ALTO) program utilizes protocols that primarily target five common conditions: renal colic, sciatica, headaches, musculoskeletal pain, and extremity fractures...
June 2016: ED Management: the Monthly Update on Emergency Department Management
https://www.readbyqxmd.com/read/27102780/zika-virus-infection-during-pregnancy-and-microcephaly-occurrence-a-review-of-literature-and-brazilian-data
#12
REVIEW
Newton Sérgio De Carvalho, Beatriz Freitas De Carvalho, Cyllian Arias Fugaça, Bruna Dóris, Evellyn Silverio Biscaia
In November of 2015, the Ministry of Health of Brazil published an announcement confirming the relationship between Zika virus and the microcephaly outbreak in the Northeast, suggesting that infected pregnant women might have transmitted the virus to their fetuses. The objectives of this study were to conduct a literature review about Zika virus infection and microcephaly, evaluate national and international epidemiological data, as well as the current recommendations for the health teams. Zika virus is an arbovirus, whose main vector is the Aedes sp...
May 2016: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27046585/wearable-ultrasound-array-for-point-of-care-imaging-and-patient-monitoring
#13
Andrzej P Mierzwa, Sean P Huang, Kristen T Nguyen, Martin O Culjat, Rahul S Singh
A versatile, flexible piezoceramic array has been developed for a variety of ultrasound applications. The transducer can be configured as a linear or curvilinear transducer array, or mounted directly onto the body as a patch or wearable device. Results using a prototype 16-element array demonstrated equivalence to commercial linear array probes in accuracy of vessel diameter measurements in vascular phantoms. The ability to view needle insertion for peripherally inserted central catheter (PICC) procedures was also demonstrated...
2016: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/26955039/real-time-detection-and-monitoring-of-acute-brain-injury-utilizing-evoked-electroencephalographic-potentials
#14
Jonathan A N Fisher, Stanley Huang, Meijun Ye, Marjan Nabili, W Bryan Wilent, Victor Krauthamer, Matthew R Myers, Cristin G Welle
Rapid detection and diagnosis of a traumatic brain injury (TBI) can significantly improve the prognosis for recovery. Helmet-mounted sensors that detect impact severity based on measurements of acceleration or pressure show promise for aiding triage and transport decisions in active, field environments such as professional sports or military combat. The detected signals, however, report on the mechanics of an impact rather than directly indicating the presence and severity of an injury. We explored the use of cortical somatosensory evoked electroencephalographic potentials (SSEPs) to detect and track, in real-time, neural electrophysiological abnormalities within the first hour following head injury in an animal model...
September 2016: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/26413296/deep-bleeder-acoustic-coagulation-dbac-part-ii-in-vivo-testing-of-a-research-prototype-system
#15
K Michael Sekins, Stephen R Barnes, Liexiang Fan, Jerry D Hopple, Stephen J Hsu, John Kook, Chi-Yin Lee, Caroline Maleke, Xiaozheng Jenny Zeng, Romain Moreau-Gobard, Alexis Ahiekpor-Dravi, Gareth Funka-Lea, John Eaton, Keith Wong, Scott Keneman, Stuart B Mitchell, Barbrina Dunmire, John C Kucewicz, Fred J Clubb, Matthew W Miller, Lawrence A Crum
BACKGROUND: Deep Bleeder Acoustic Coagulation (DBAC) is an ultrasound image-guided high-intensity focused ultrasound (HIFU) method proposed to automatically detect and localize (D&L) and treat deep, bleeding, combat wounds in the limbs of soldiers. A prototype DBAC system consisting of an applicator and control unit was developed for testing on animals. To enhance control, and thus safety, of the ultimate human DBAC autonomous product system, a thermal coagulation strategy that minimized cavitation, boiling, and non-linear behaviors was used...
2015: Journal of Therapeutic Ultrasound
https://www.readbyqxmd.com/read/26308515/paediatric-regional-anaesthesia-a-current-perspective
#16
REVIEW
Mihaela Visoiu
PURPOSE OF REVIEW: Effective analgesia is necessary for optimal recovery after surgery, but children often do not attain adequate postoperative pain control. This review examines the current trends in paediatric regional anaesthesia. RECENT FINDINGS: Better pain assessment and therapeutic regimens are needed for our patients. Trunk blocks such as paravertebral, transversus abdominis plane, rectus sheath and ilioinguinal/iliohypogastric are becoming a popular means of providing analgesia for thoracic and abdominal procedures...
October 2015: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/26284310/initial-investigation-of-a-novel-noninvasive-weight-loss-therapy-using-mri-guided-high-intensity-focused-ultrasound-mr-hifu-of-visceral-fat
#17
Patrick M Winter, Matthew Lanier, Ari Partanen, Charles Dumoulin
PURPOSE: MRI-guided high intensity focused ultrasound (MR-HIFU) allows noninvasive heating of deep tissues. Specifically targeting visceral fat deposits with MR-HIFU could offer an effective therapy for reversing the development of obesity, diabetes, and metabolic syndrome. METHODS: Overweight rats received either MR-HIFU of visceral fat, sham treatment, no treatment, or ex vivo temperature calibration. Conventional MR thermometry methods are not effective in fat tissue...
July 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/26207980/fetal-growth-restriction-and-intra-uterine-growth-restriction-guidelines-for-clinical-practice-from-the-french-college-of-gynaecologists-and-obstetricians
#18
C Vayssière, L Sentilhes, A Ego, C Bernard, D Cambourieu, C Flamant, G Gascoin, A Gaudineau, G Grangé, V Houfflin-Debarge, B Langer, V Malan, P Marcorelles, J Nizard, F Perrotin, L Salomon, M-V Senat, A Serry, V Tessier, P Truffert, V Tsatsaris, C Arnaud, B Carbonne
Small for gestational age (SGA) is defined by weight (in utero estimated fetal weight or birth weight) below the 10th percentile (professional consensus). Severe SGA is SGA below the third percentile (professional consensus). Fetal growth restriction (FGR) or intra-uterine growth restriction (IUGR) usually correspond with SGA associated with evidence indicating abnormal growth (with or without abnormal uterine and/or umbilical Doppler): arrest of growth or a shift in its rate measured longitudinally (at least two measurements, 3 weeks apart) (professional consensus)...
October 2015: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/26170708/assessment-of-clinical-effects-and-safety-of-an-oral-supplement-based-on-marine-protein-vitamin-c-grape-seed-extract-zinc-and-tomato-extract-in-the-improvement-of-visible-signs-of-skin-aging-in-men
#19
Adilson Costa, Elisangela Samartin Pegas Pereira, Elvira Cancio Assumpção, Felipe Borba Calixto Dos Santos, Fernanda Sayuri Ota, Margareth de Oliveira Pereira, Maria Carolina Fidelis, Raquel Fávaro, Stephanie Selma Barros Langen, Lúcia Helena Favaro de Arruda, Eva Nydal Abildgaard
BACKGROUND: Skin aging is a natural process that may be aggravated by environmental factors. Topical products are the conventional means to combat aging; however, the use of oral supplements is on the rise to assist in the management of aged skin. OBJECTIVE: The purpose of this study was to assess the effects and safety of an oral supplement containing (per tablet) marine protein (105 mg), vitamin C (27 mg), grape seed extract (13.75 mg), zinc (2 mg), and tomato extract (14...
2015: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/26031200/can-a-combination-of-ultrasonographic-parameters-accurately-evaluate-concussion-and-guide-return-to-play-decisions
#20
Michael S Cartwright, Janae E Dupuis, Jessica M Bargoil, Dana C Foster
Mild traumatic brain injury, often referred to as concussion, is a common, potentially debilitating, and costly condition. One of the main challenges in diagnosing and managing concussion is that there is not currently an objective test to determine the presence of a concussion and to guide return-to-play decisions for athletes. Traditional neuroimaging tests, such as brain magnetic resonance imaging, are normal in concussion, and therefore diagnosis and management are guided by reported symptoms. Some athletes will under-report symptoms to accelerate their return-to-play and others will over-report symptoms out of fear of further injury or misinterpretation of underlying conditions, such as migraine headache...
September 2015: Medical Hypotheses
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