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https://www.readbyqxmd.com/read/29316800/pro-dopamine-regulator-kb220z-attenuates-hoarding-and-shopping-behavior-in-a-female-diagnosed-with-sud-and-adhd
#1
Thomas McLaughlin, Kenneth Blum, Bruce Steinberg, Edward J Modestino, Lyle Fried, David Baron, David Siwicki, Eric R Braverman, Rajendra D Badgaiyan
Background Addictive-like behaviors (e.g., hoarding and shopping) may be the result of the cumulative effects of dopaminergic and other neurotransmitter genetic variants as well as elevated stress levels. We, therefore, propose that dopamine homeostasis may be the preferred goal in combating such challenging and unwanted behaviors, when simple dopaminergic activation through potent agonists may not provide any resolution. Case presentation C.J. is a 38-year-old, single, female, living with her mother. She has a history of substance use disorder as well as attention deficit hyperactivity disorder, inattentive type...
January 10, 2018: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/29301668/brain-structural-correlates-of-subclinical-obsessive-compulsive-symptoms-in-healthy-children
#2
Maria Suñol, Oren Contreras-Rodríguez, Dídac Macià, Gerard Martínez-Vilavella, Ignacio Martínez-Zalacaín, Marta Subirà, Jesús Pujol, Jordi Sunyer, Carles Soriano-Mas
OBJECTIVE: Subclinical obsessive-compulsive (OC) symptoms are frequently observed in children and have been reported to predict a subsequent diagnosis of OC disorder (OCD). Therefore, identifying the putative neurobiological signatures of such risk is crucial, because it would allow for the characterization of the underpinnings of OCD without the interfering effects of chronicity, medication, or comorbidities, especially when interpreted within the context of OCD clinical heterogeneity and taking into account normal neurodevelopmental changes...
January 2018: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/29260359/an-effort-toward-molecular-neuroeconomics-of-food-deprivation-induced-food-hoarding-in-mice-focus-on-xanthine-oxidoreductase-gene-expression-and-xanthine-oxidase-activity
#3
Isaac Karimi, Shima Motamedi, Lora A Becker
The crucial role of xanthine oxidoreductase (XOR) gene and its active isoform, xanthine oxidase (XO), in purine metabolism and cellular oxidative status led us to investigative their fluctuations in food deprivation induced food hoarding in mice. After, 10 h food deprivation, mice that hoarded lesser than 5 g were considered as 'low-hoarders' while mice that hoarded higher than 20 g were considered as 'high-hoarders'. Mice who hoarded between 5 to 20 g of food were excluded from study. An increase (1.133-fold) in encephalic XOR expression has been found in high-hoarders compared with low-hoarders without sex consideration...
December 19, 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/29251003/the-physiology-and-toxicology-of-acute-inhalation-phosphine-poisoning-in-conscious-male-rats
#4
Benjamin Wong, Rebecca Lewandowski, Justin Tressler, Katherine Sherman, Jaclynn Andres, Jennifer Devorak, Cristin Rothwell, Tracey Hamilton, Heidi Hoard-Fruchey, Alfred M Sciuto
Phosphine (PH3) is a toxidrome-spanning chemical that is widely used as an insecticide and rodenticide. Exposure to PH3 causes a host of target organ and systemic effects, including oxidative stress, cardiopulmonary toxicity, seizure-like activity and overall metabolic disturbance. A custom dynamic inhalation gas exposure system was designed for the whole-body exposure of conscious male Sprague-Dawley rats (250-350 g) to PH3. An integrated plethysmography system was used to collect respiratory parameters in real-time before, during and after PH3 exposure...
December 18, 2017: Inhalation Toxicology
https://www.readbyqxmd.com/read/29239120/a-call-for-prevention-and-early-intervention-in-obsessive-compulsive-disorder
#5
REVIEW
Vlasios Brakoulias, Iain E Perkes, Emmanouil Tsalamanios
BACKGROUND: Evidence suggests that many people with obsessive-compulsive disorder (OCD) have subclinical symptoms years before the development of their disorder and that early treatment may reduce its severity. AIM: To explore prevention and early intervention strategies for OCD. METHODS: A narrative literature review was conducted. RESULTS: The literature in relation to the prevention of OCD is sparse. Genetic and environmental factors appear to be relevant to the aetiology of OCD, for example, the observation that hoarding symptoms and contamination/cleaning symptoms are more likely to also be present in first-degree relatives...
December 14, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29232962/meaning-in-hoarding-perspectives-of-people-who-hoard-on-clutter-culture-and-agency
#6
David M R Orr, Michael Preston-Shoot, Suzy Braye
Hoarding has become increasingly prominent in clinical practice and popular culture in recent years, giving rise to extensive research and commentary. Critical responses in the social sciences have criticised the cultural assumptions built in to the construct of 'hoarding disorder' and expressed fears that it may generate stigma outweighing its benefits; however, few of these studies have engaged directly with 'hoarders' themselves. This paper reports on in-depth, semi-structured interviews with 10 individuals living in England, who received assessment and intervention for hoarding from Social Services...
December 12, 2017: Anthropology & Medicine
https://www.readbyqxmd.com/read/29191148/a-workshop-to-engage-community-stakeholders-to-deliver-evidence-based-treatment-for-hoarding-disorder-a-pilot-study
#7
Jordan Wilson, Erik Wilkerson, Maria Filippou-Frye, Carolyn Rodriguez
No abstract text is available yet for this article.
December 1, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/29185879/early-conceptual-understanding-of-cardinality-predicts-superior-school-entry-number-system-knowledge
#8
David C Geary, Kristy vanMarle, Felicia W Chu, Jeffrey Rouder, Mary K Hoard, Lara Nugent
We demonstrate a link between preschoolers' quantitative competencies and their school-entry knowledge of the relations among numbers (number-system knowledge). The quantitative competencies of 141 children (69 boys) were assessed at the beginning of preschool and throughout the next 2 years of preschool, as was their mathematics and reading achievement at the end of kindergarten and their number-system knowledge at the beginning of first grade. A combination of Bayes analyses and standard regressions revealed that the age at which the children had the conceptual insight that number words represent specific quantities (cardinal value) was strongly related to their later number-system knowledge and was more consistently related to broader mathematics than to reading achievement, controlling for intelligence, executive function, and parental education levels...
November 1, 2017: Psychological Science
https://www.readbyqxmd.com/read/29179846/-supporting-people-with-diogenes-syndrome
#9
REVIEW
Claire Patry, Sylvain Closier, Élise Lafon, Corine Carlier-Verhaeghe, Angélique Kerrien, Armelle Bertrand, Emmanuelle Caudron
Diogenes syndrome is a chronic condition often affecting elderly people, especially those living in isolation. It is characterised by self-neglect and compulsive hoarding. Medico-social professionals working with people in their home, have reflected on levers to help improve the complex support of these patients.
December 2017: Revue de L'infirmière
https://www.readbyqxmd.com/read/29170732/changes-in-saving-cognitions-mediate-hoarding-symptom-change-in-cognitive-behavioral-therapy-for-hoarding-disorder
#10
Hannah C Levy, Blaise L Worden, Christina M Gilliam, Christine D'Urso, Gail Steketee, Randy O Frost, David F Tolin
Cognitive-behavioral therapy (CBT) is an empirically-supported treatment for hoarding disorder (HD). However, meta-analytic studies suggest that CBT is only modestly effective, and a significant number of individuals with HD remain symptomatic following treatment. To inform the development of more effective and targeted treatments, it will be important to clarify the mechanisms of treatment response in CBT for HD. To this end, the current study examined whether change in maladaptive saving beliefs mediated symptom change in CBT for HD...
July 2017: Journal of Obsessive-compulsive and related Disorders
https://www.readbyqxmd.com/read/29168614/eastern-gray-squirrels-are-consistent-shoppers-of-seed-traits-insights-from-discrete-choice-experiments
#11
Mekala Sundaram, Nathanael I Lichti, Nicole J Olynk Widmar, Robert K Swihart
Seeds of many hardwood trees are dispersed by scatter-hoarding rodents, and this process is often mediated by the traits of seeds. Although numerous studies have linked seed traits to seed preference by rodents, little is known about how rodents forage for seeds when multiple desirable and undesirable seed traits are available simultaneously. Here, we adopt a novel method of designing choice experiments to study how eastern gray squirrels (Sciurus carolinensis) select for 6 traits (caloric value, protein content, tannin concentration, kernel mass, dormancy period and toughness of shell) among seeds...
November 23, 2017: Integrative Zoology
https://www.readbyqxmd.com/read/29161672/interpersonal-trauma-and-hoarding-the-mediating-role-of-aggression
#12
Brittany M Mathes, Amberly K Portero, Brittany A Gibby, Savannah L King, Amanda M Raines, Norman B Schmidt
BACKGROUND: A growing body of literature indicates that exposure to interpersonal trauma contributes to the onset or exacerbation of hoarding symptoms. However, little research has explored psychosocial factors that may help to explain the relationship between interpersonal trauma and hoarding symptoms. One outcome of trauma exposure that may be associated with hoarding symptoms is aggression, defined as the tendency to experience and express hostility and anger, and to engage in aggressive behavior...
November 14, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29154203/unbending-mind-individuals-with-hoarding-disorder-do-not-modify-decision-strategy-in-response-to-feedback-under-risk
#13
Helen Pushkarskaya, David F Tolin, Daniel Henick, Ifat Levy, Christopher Pittenger
Cognitive-behavioral models of hoarding disorder emphasize impairments in information processing and decision making in the genesis of hoarding symptomology. We propose and test the novel hypothesis that individuals with hoarding are maladaptively biased towards a deliberative decision style. While deliberative strategies are often considered normative, they are not always adaptable to the limitations imposed by many real-world decision contexts. We examined decision-making patterns in 19 individuals with hoarding and 19 healthy controls, using a behavioral task that quantifies selection of decision strategies in a novel environment with known probabilities (risk) in response to feedback...
November 2, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29145187/diogenes-syndrome
#14
Frédéric Assal
Diogenes syndrome (DS) is not a specific disease but a real neurobehavioral syndrome, characterized by severe domestic squalor, pathological hoarding, lack of insight into the condition, and no need for help. DS can be secondary when associated to psychosis or bipolar disorder, or primary when it occurs as a single entity, usually in the elderly. DS is a clinically complex transnosographic syndrome for which multidimensional approaches need to be considered: medical, psychiatric, neurological, social, scientific, and ethical...
2018: Frontiers of Neurology and Neuroscience
https://www.readbyqxmd.com/read/29127561/the-role-of-public-health-in-the-development-of-a-collaborative-agreement-with-rural-and-semi-urban-partners-in-cases-of-severe-domestic-squalor-and-hoarding
#15
Marie-Claude Lacombe, Bruno Cossette
When confronted with complex situations of hoarding and severe domestic squalor, small municipal communities and their partners frequently feel overwhelmed due to limited resources at their disposal. Stakeholders often report these situations to Public Health Service and seek their support. In order to facilitate more effective and coordinated actions, the main stakeholders involved (municipal, fire, police, public health and the regional health center) must agree on the most appropriate intervention strategies...
November 10, 2017: Community Mental Health Journal
https://www.readbyqxmd.com/read/29118416/protein-nutrition-governs-within-host-race-of-honey-bee-pathogens
#16
Manuel Tritschler, Jutta J Vollmann, Orlando Yañez, Nor Chejanovsky, Karl Crailsheim, Peter Neumann
Multiple infections are common in honey bees, Apis mellifera, but the possible role of nutrition in this regard is poorly understood. Microsporidian infections, which are promoted by protein-fed, can negatively correlate with virus infections, but the role of protein nutrition for the microsporidian-virus interface is unknown. Here, we challenged naturally deformed wing virus - B (DWV-B) infected adult honey bee workers fed with or without pollen ( = protein) in hoarding cages, with the microsporidian Nosema ceranae...
November 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29110334/frontotemporal-dementia-with-trans-activation-response-dna-binding-protein-43-presenting-with-catatonic-syndrome
#17
Ryohei Watanabe, Ito Kawakami, Mitsumoto Onaya, Shinji Higashi, Nobutaka Arai, Haruhiko Akiyama, Masato Hasegawa, Tetsuaki Arai
Catatonia is a clinical syndrome characterized by symptoms such as immobility, mutism, stupor, stereotypy, echophenomena, catalepsy, automatic obedience, posturing, negativism, gegenhalten and ambitendency. This syndrome occurs mostly in mood disorder and schizophrenic patients, and is related to neuronal dysfunction involving the frontal lobe. Some cases of frontotemporal dementia (FTD) with catatonia have been reported, but these cases were not examined by autopsy. Here, we report on a FTD case which showed catatonia after the first episode of brief psychotic disorder...
November 7, 2017: Neuropathology: Official Journal of the Japanese Society of Neuropathology
https://www.readbyqxmd.com/read/29108463/td-the-case-of-diogenes-syndrome-deficit-or-denial
#18
Fiona Ashworth, Anita Rose, Barbara A Wilson
Diogenes Syndrome (DS) is characterised by extreme self-neglect, domestic squalor, hoarding, social withdrawal, and lack of concern and shame for the individual's residential situation. This paper describes TD who was unable to identify emotional expressions of disgust and was borderline-impaired for facial recognition associated with perceptual difficulties. Problems interpreting expressions of disgust were interesting as TD was living in squalor, neglecting himself, and lacked concern for his circumstances...
November 6, 2017: Neuropsychological Rehabilitation
https://www.readbyqxmd.com/read/29045417/effects-of-food-store-quality-on-hibernation-performance-in-common-hamsters
#19
Carina Siutz, Matthias Nemeth, Karl-Heinz Wagner, Ruth Quint, Thomas Ruf, Eva Millesi
Hibernating animals can adjust torpor expression according to available energy reserves. Besides the quantity, the quality of energy reserves could play an important role for overwintering strategies. Common hamsters are food-storing hibernators and show high individual variation in hibernation performance, which might be related to the quality of food hoards in the hibernacula. In this study, we tested the effects of food stores high in fat content, particularly polyunsaturated fatty acids (PUFAs), on hibernation patterns under laboratory conditions...
2017: PloS One
https://www.readbyqxmd.com/read/29044477/association-between-neighborhood-cohesion-and-self-neglect-in-chinese-american-older-adults
#20
Ailian Hei, XinQi Dong
OBJECTIVES: To examine the association between neighborhood cohesion and risk of self-neglect in a community-dwelling Chinese-American older population. SETTING: Community. PARTICIPANTS: Chinese-American older adults aged 60 and older interviewed from 2011 to 2013 (N = 3,159). DESIGN: Data were drawn from the Population Study of Chinese Elderly, a cross-sectional community-engaged study in the greater Chicago area...
October 17, 2017: Journal of the American Geriatrics Society
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