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https://www.readbyqxmd.com/read/29449443/sex-differences-in-ischemic-heart-disease-advances-obstacles-and-next-steps
#1
Niti R Aggarwal, Hena N Patel, Laxmi S Mehta, Rupa M Sanghani, Gina P Lundberg, Sandra J Lewis, Marla A Mendelson, Malissa J Wood, Annabelle S Volgman, Jennifer H Mieres
Evolving knowledge of sex-specific presentations, improved recognition of conventional and novel risk factors, and expanded understanding of the sex-specific pathophysiology of ischemic heart disease have resulted in improved clinical outcomes in women. Yet, ischemic heart disease continues to be the leading cause of morbidity and mortality in women in the United States. The important publication by the Institute of Medicine titled "Women's Health Research-Progress, Pitfalls, and Promise," highlights the persistent disparities in cardiovascular disease burden among subgroups of women, particularly women who are socially disadvantaged because of race, ethnicity, income level, and educational attainment...
February 2018: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/29448963/academic-medical-centers-as-innovation-ecosystems-to-address-population-omics-challenges-in-precision-medicine
#2
REVIEW
Patrick J Silva, Valerie M Schaibley, Kenneth S Ramos
While the promise of the Human Genome Project provided significant insights into the structure of the human genome, the complexities of disease at the individual level have made it difficult to utilize -omic information in clinical decision making. Some of the existing constraints have been minimized by technological advancements that have reduced the cost of sequencing to a rate far in excess of Moore's Law (a halving in cost per unit output every 18 months). The reduction in sequencing costs has made it economically feasible to create large data commons capturing the diversity of disease across populations...
February 15, 2018: Journal of Translational Medicine
https://www.readbyqxmd.com/read/29445922/education-on-the-business-of-plastic-surgery-during-training-a-survey-of-plastic-surgery-residents
#3
Steven A Ovadia, Kriya Gishen, Urmen Desai, Alejandro M Garcia, Seth R Thaller
BACKGROUND: Entrepreneurial skills are important for physicians, especially plastic surgeons. Nevertheless, these skills are not typically emphasized during residency training. OBJECTIVE: Evaluate the extent of business training at plastic surgery residency programs as well as means of enhancing business training. METHODS: A 6-question online survey was sent to plastic surgery program directors for distribution to plastic surgery residents...
February 14, 2018: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29433626/metal-oxides-as-a-biostimulator-for-upregulation-of-genes-involved-in-the-biosynthesis-of-rebaudioside-a
#4
Alireza Mirzaei, Gholamreza Kavoosi, Sara Dezhsetan, Mahdi Behnamian
Stevia rebaudiana Bertoni is a kind of perennial medicinal plant with sweetening properties which belongs to Asteraceae family. Its leaves with fundamental glycoside compounds consist of both a sugar part and a non-sugar sector. One of the glycoside compounds is Rebaudioside- A which has a greater importance in business. This experiment was conducted to evaluate the effects of Ag2O, CrO3, PbO, Fe2O3, BaO and TiO2 on the expression pattern of these genes in the Stevia rebaudiana. Rebaudioside- A biosynthesis was repeated 3 times with concentrations of 50, 100 and 200µM...
February 10, 2018: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/29401211/shared-decision-making-during-inpatient-rounds-opportunities-for-improvement-in-patient-engagement-and-communication
#5
Rebecca Blankenburg, Joan F Hilton, Patrick Yuan, Stephanie Rennke, Brad Monash, Stephanie M Harman, Debbie S Sakai, Poonam Hosamani, Adeena Khan, Ian Chua, Eric Huynh, Lisa Shieh, Lijia Xie
BACKGROUND: Shared decision-making (SDM) improves patient engagement and may improve outpatient health outcomes. Little is known about inpatient SDM. OBJECTIVE: To assess overall quality, provider behaviors, and contextual predictors of SDM during inpatient rounds on medicine and pediatrics hospitalist services. DESIGN: A 12-week, cross-sectional, single-blinded observational study of team SDM behaviors during rounds, followed by semistructured patient interviews...
February 5, 2018: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/29400005/optimizing-patient-care-and-outcomes-through-the-congenital-heart-center-of-the-21st-century
#6
Jeffery B Anderson, Devyani Chowdhury, Jean A Connor, Curt J Daniels, Craig E Fleishman, Michael Gaies, Jeffrey Jacobs, John Kugler, Nicolas Madsen, Robert H Beekman, Stacey Lihn, Kay Stewart-Huey, Robert Vincent, Robert Campbell
Pediatric cardiovascular services are responding to the dynamic changes in the medical environment, including the business of medicine. The opportunity to advance our pediatric cardiology field through collaboration is now realized, permitting us to define meaningful quality metrics and establish national benchmarks through multicenter efforts. In March 2016, the American College of Cardiology hosted the first Adult Congenital/Pediatric Cardiology Section Congenital Heart Community Day. This was an open participation meeting for clinicians, administrators, patients/parents to propose metrics that optimize patient care and outcomes for a state-of-the-art congenital heart center of the 21st century...
February 5, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/29371194/development-and-implementation-of-a-centralized-comprehensive-refill-authorization-program-in-an-academic-health-system
#7
Matthew H Rim, Karen C Thomas, Brittanie Hatch, Michael Kelly, Linda S Tyler
PURPOSE: The development and implementation of a centralized, comprehensive, refill authorization (CCRA) program within an academic health system are described. SUMMARY: In order to improve continuity of care for our medically complicated patients, ambulatory pharmacy services developed and implemented a highly coordinated CCRA program for multiple community clinics within the system. To implement the CCRA program, we centralized the refill-request intake process to the Pharmacy Ambulatory Clinical Care Center (PAC3)...
February 1, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29361506/supplementing-resident-research-funding-through-a-partnership-with-local-industry
#8
Steven J Skube, Elliot G Arsoniadis, Cyrus Jahansouz, Sherri Novitsky, Jeffrey G Chipman
OBJECTIVE: To develop a model for the supplementation of resident research funding through a resident-hosted clinical immersion with local industry. DESIGN: Designated research residents hosted multiple groups of engineers and business professionals from local industry in general surgery-focused clinical immersion weeks. The participants in these week-long programs are educated about general surgery and brought to the operating room to observe a variety of surgeries...
January 17, 2018: Journal of Surgical Education
https://www.readbyqxmd.com/read/29358030/the-future-of-pharmacy-practice-research-perspectives-of-academics-and-practitioners-from-australia-nz-united-kingdom-canada-and-usa
#9
Zaheer-Ud-Din Babar, Shane Scahill, Raveena Amee Nagaria, Louise E Curley
BACKGROUND: Healthcare is under significant pressure with the explosion of long term conditions, shift in worldwide demographics and is evolving through advances in technology. Aligned with this is the changing role of pharmacy from the traditional dispenser of medicines to having (in addition) a more advanced clinical role. This study aimed to understand what the pharmacy practice research agenda might look like from the viewpoint of pharmacy academics and practitioners across five high-income countries...
January 11, 2018: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/29357339/do-pain-medicine-fellowship-programs-provide-education-in-practice-management-a-survey-of-pain-medicine-fellowship-programs
#10
Rene Przkora, Ajay Antony, Andrew McNeil, Gary J Brenner, James Mesrobian, Richard Rosenquist, Amr E Abouleish
BACKGROUND: We hypothesized that there is a gap between expectations and actual training in practice management for pain medicine fellows. Our impression is that many fellowships rely on residency training to provide exposure to business education. Unfortunately, pain management and anesthesiology business education are very different, as the practice settings are largely office- versus hospital-based, respectively. OBJECTIVE: Because it is unclear whether pain management fellowships are providing practice management education and, if they do, whether the topics covered match the expectations of their fellows, we surveyed pain medicine program directors and fellows regarding their expectations and training in business management...
January 2018: Pain Physician
https://www.readbyqxmd.com/read/29349812/drug-promotion-practices-a-review
#11
Nilan T Jacob
Over the years, the pharmaceutical industry has been at the forefront of research and innovation in drug discovery and development. The process of drug discovery extending from pre-clinical studies to multi-centric clinical trials and post-marketing phase is a costly affair running into billions of dollars. On the flip side, not all investigational molecules clear the trial phases and get approved; which puts pressure on the manufacturers to maximise the profit from approved drugs. It is in this key area, the practice of drug promotion plays its role...
January 18, 2018: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29318826/-design-and-implementation-of-real-time-control-of-changes-to-national-chinese-medicine-resources-fill-system-based-on-gis
#12
Tian Zhang, Jun-de Li, Meng Cheng, Ying Li, Zhong-Bin Lin, Yi-Hua Shen, Lu-Qi Huang
The dynamic monitoring data of traditional Chinese medicine resources is one of the important tasks of the dynamic monitoring system of Chinese medicine resources,the system has formed a periodic monitoring data reporting mechanism. Data authenticity and accuracy are the basis for the sustainable and healthy development of Chinese medicine resources dynamic monitoring,information technology is an effective means to improve the efficiency of data reporting, reporting quality. Data production based on dynamic monitoring is of great significance for grasp the trend of change and development of Chinese medicine resources...
November 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29315916/ethical-responsibilities-of-pharmacists-when-selling-complementary-medicines-a-systematic-review
#13
REVIEW
Amber Salman Popattia, Sarah Winch, Adam La Caze
OBJECTIVE: The widespread sale of complementary medicines in community pharmacy raises important questions regarding the responsibilities of pharmacists when selling complementary medicines. This study reviews the academic literature that explores a pharmacist's responsibilities when selling complementary medicines. METHODS: International Pharmaceutical Abstracts, Embase, PubMed, Cinahl, PsycINFO and Philosopher's index databases were searched for articles written in English and published between 1995 and 2017...
January 8, 2018: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/29313034/the-wyss-institute-a-new-model-for-medical-technology-innovation-and-translation-across-the-academic-industrial-interface
#14
REVIEW
Mary Tolikas, Ayis Antoniou, Donald E Ingber
The Wyss Institute for Biologically Inspired Engineering at Harvard University was formed based on the recognition that breakthrough discoveries cannot change the world if they never leave the laboratory. The Institute's mission is to discover the biological principles that Nature uses to build living things, and to harness these insights to create biologically inspired engineering innovations to advance human health and create a more sustainable world. Since its launch in 2009, the Institute has developed a new model for innovation, collaboration, and technology translation within academia, breaking "silos" to enable collaborations that cross institutional and disciplinary barriers...
September 2017: Bioengineering & Translational Medicine
https://www.readbyqxmd.com/read/29296568/current-status-and-future-prospects-of-research-and-development-operations-in-traditional-and-complementary-and-alternative-medicine-manufacturing-small-and-medium-sized-enterprises-a-2014-company-based-survey
#15
Miyoung Ahn, Eun-Ji Park, Jong-Min Woo
Background: Small- and medium-sized enterprises (SMEs) have played key roles in the economic growth and technical innovation of traditional and complementary and alternative medicine (T&CM). Research and development (R&D) are critical activities for industrial progress. This study aimed to characterize the current status of SME R&D activities and to explore manufacturers' perceptions of R&D expansion. Methods: Records of the distribution of T&CM SMEs and R&D resources detailed in the 2014 Statistics of Korea T&CM Industries survey, a previously conducted survey on the industrial status of the T&CM field, were reviewed...
December 2017: Integrative Medicine Research
https://www.readbyqxmd.com/read/29226349/what-do-we-know-about-coaching-in-medical-education-a-literature-review
#16
REVIEW
Ben Lovell
CONTEXT: Coaching has been employed successfully in the competitive sports, professional music, and business and corporate worlds. It is now emerging as a training modality in medical education. OBJECTIVES: This paper reviews the current evidence on coaching strategies for doctors and medical students. METHODS: An applied literature search was conducted in PubMed, MEDLINE and Web of Science. Predetermined definitions of coaching interventions and their evaluations were used to narrow 993 papers down to 21, which were included in the final review...
December 11, 2017: Medical Education
https://www.readbyqxmd.com/read/29226230/new-paths-in-post-graduate-medical-training-in-general-practice-8-years-of-experience-with-the-pilot-project-verbundweiterbildungplus-baden-w%C3%A3-rttemberg
#17
Simon Schwill, Julia Magez, Stefanie Joos, Jost Steinhäuser, Thomas Ledig, Aline Rubik, Wilhelm Niebling, Joachim Szecsenyi, Elisabeth Flum
Background: In face of the looming shortage of general practitioners, primary healthcare providers and post-graduate training in general practice are increasingly becoming part of the political agenda in Germany. In 2009 the program "Verbundweiterbildung plus Baden-Württemberg" (VWB plus BW) was developed by the Competence Center for General Practice in Baden-Wuerttemberg to ensure primary healthcare in the future by enhancing the attractiveness of general medicine. This paper describes the experiences that have been gathered in developing a post-graduate training-program for physicians undergoing specialist training in general practice...
2017: GMS Journal for Medical Education
https://www.readbyqxmd.com/read/29225667/interactive-k-means-clustering-method-based-on-user-behavior-for-different-analysis-target-in-medicine
#18
Yang Lei, Dai Yu, Zhang Bin, Yang Yang
Clustering algorithm as a basis of data analysis is widely used in analysis systems. However, as for the high dimensions of the data, the clustering algorithm may overlook the business relation between these dimensions especially in the medical fields. As a result, usually the clustering result may not meet the business goals of the users. Then, in the clustering process, if it can combine the knowledge of the users, that is, the doctor's knowledge or the analysis intent, the clustering result can be more satisfied...
2017: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/29225002/documentation-of-plant-drugs-dispensed-via-local-weekly-shanties-of-madurai-city-india
#19
Tagadur Sureshchandra Suma, Kaliamoorthy Ravikumar, Byadarahalli Srikantiah Somashekhar, Devendra Kumar Ved, Roohi Zaman, Gopalakrishnan Rajalakshmi, S N Venugopalan Nair, Subrahmanya Kumar Kukkupuni
BACKGROUND: The Valaiyār (Moopanar) communities of Tamil Nadu are traditionally known for catching rats and snakes from the agricultural fields. Prior to independence, some of these families have faced socio-economic changes and chosen to become herbalists in Madurai city. They are mainly engaged in collecting and dispensing fresh and dried plant drugs in its 'natural form' at Tiḷagar tīḍal market of Madurai city. Their business is unique, because customers receive 'prescriptions' and 'plant drugs', unlike the conventional dispensaries...
December 7, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29206009/hydrotherapy-and-medical-entrepreneurship-the-water-spell-of-ricardo-jorge
#20
Rui Manuel Pinto Costa
Between 1886 and 1893, the doctor and hygienist Ricardo Jorge was linked to a commercial and medical project on the waters of Gerês. Known for many centuries and used for therapeutic purposes, they were administered on an empirical basis. When new chemical analyses were first published, the empirical properties of these waters took on a new role in hydrotherapy based on their now proven mineral and medicinal qualities. The article discusses in detail Ricardo Jorge's business venture, framing it in the context of the economic collection and treatment potential of mineral waters and the revival of the phenomenon of hydrotherapy, legitimized by new developments in the chemical analysis of waters...
2017: Dynamis
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