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https://www.readbyqxmd.com/read/28199324/establishing-a-reliable-framework-for-harnessing-the-creative-power-of-the-scientific-crowd
#1
Adrian J Carter, Amy Donner, Wen Hwa Lee, Chas Bountra
Discovering new medicines is difficult and increasingly expensive. The pharmaceutical industry has responded to this challenge by embracing open innovation to access external ideas. Historically, partnerships were usually bilateral, and the drug discovery process was shrouded in secrecy. This model is rapidly changing. With the advent of the Internet, drug discovery has become more decentralised, bottom-up, and scalable than ever before. The term open innovation is now accepted as just one of many terms that capture different but overlapping levels of openness in the drug discovery process...
February 2017: PLoS Biology
https://www.readbyqxmd.com/read/28170173/the-3rs-of-cell-therapy
#2
Arnold I Caplan, Chris Mason, Brock Reeve
The 3Rs for a good education are "reading, 'riting, and 'rithmetic." The basis for good health care solutions for the emergent field of cell therapy in the future will also involve 3Rs: regulation, reimbursement, and realization of value. The business models in this new field of cell therapy will involve these 3Rs. This article brings forth realities facing this new industry for its approaches to provide curative health care solutions. Stem Cells Translational Medicine 2017;6:17-21.
January 2017: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/28166580/outcomes-of-embedded-care-management-in-a-family-medicine-residency-patient-centered-medical-home
#3
Robert J Newman, Richard Bikowski, Kristy Nakayama, Tina Cunningham, Pam Acker, Dana Bradshaw
BACKGROUND AND OBJECTIVES: Much attention is devoted nationally to preventing hospital readmissions and emergency department (ED) use, given the high cost of this care. There is a growing body of evidence from the Patient Centered Primary Care Collaborative that a patient-centered medical home (PCMH) model successfully lowers these costs. Our study evaluates a specific intervention in a family medicine residency PCMH to decrease readmissions and ED utilization using an embedded care manager...
January 2017: Family Medicine
https://www.readbyqxmd.com/read/28156576/embedded-palliative-medicine-model-for-inpatient-solid-tumor-oncology-patients-utilizing-corounding-and-consultation-criteria-a-quality-improvement-pilot
#4
Bassam N Estfan, Alberto J Montero
: 148 Background: Hospitalized patients (pts) on solid tumor oncology (STO) services have palliative needs including pain management. This quality improvement project sought to establish a new STO-specific co-rounding PM consult service, evaluate the use of consult criteria for STO inpatients, assess the impact/interest in an embedded service, improve access to PM for STO pts and improve palliative education to STO teams. METHODS: During October 2015 to January 2016, a new PM consult service was established for the 2 STO inpatient services at Cleveland Clinic...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28128788/a-workplace-modified-duty-program-for%C3%A2-employees-in-an-oncology-center
#5
Elpidoforos S Soteriades
BACKGROUND: Workplace modified duty programs may provide reasonable accommodations to employees who have partial temporary job disability and could work on duty accommodations until they fully recover. However, little is known about the implementation barriers and effectiveness of such programs. OBJECTIVE: This study is aimed at evaluating the implementation of a modified duty program for employees in an oncology center. METHODS: A modified duty program for employees working at the Bank of Cyprus Oncology Center, a non profit organization with 200 employees located in the Republic of Cyprus was evaluated based on the health records of the occupational medicine department...
January 23, 2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/28126353/auditing-access-to-outpatient-rehabilitation-services-for-children-with-traumatic-brain-injury-and-public-insurance-in-washington-state
#6
Molly M Fuentes, Leah Thompson, D Alex Quistberg, Wren L Haaland, Karin Rhodes, Deborah Kartin, Cheryl Kerfeld, Susan Apkon, Ali Rowhani-Rahbar, Frederick P Rivara
OBJECTIVE: Identify insurance-based disparities in access to outpatient pediatric neurorehabilitation services. DESIGN: Audit study, with paired calls where callers posed as a mother seeking services for a simulated child with history of severe traumatic brain injury (TBI) and public or private insurance. SETTING: Outpatient rehabilitation clinics in Washington State PARTICIPANTS: 195 physical therapy clinics (PTc), 109 occupational therapy clinics (OTc), 102 speech therapy clinics (STc) and 11 rehabilitation medicine clinics INTERVENTIONS: None MAIN OUTCOME MEASURES: Acceptance of public insurance, business days until the next available appointment...
January 23, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28122905/burnout-career-satisfaction-and-well-being-among-us-neurologists-in-2016
#7
Neil A Busis, Tait D Shanafelt, Christopher M Keran, Kerry H Levin, Heidi B Schwarz, Jennifer R Molano, Thomas R Vidic, Joseph S Kass, Janis M Miyasaki, Jeff A Sloan, Terrence L Cascino
OBJECTIVE: To study prevalence of and factors that contribute to burnout, career satisfaction, and well-being in US neurologists. METHODS: A total of 4,127 US American Academy of Neurology member neurologists who had finished training were surveyed using validated measures of burnout, career satisfaction, and well-being from January 19 to March 21, 2016. RESULTS: Response rate was 40.5% (1,671 of 4,127). Average age of participants was 51 years, with 65...
January 25, 2017: Neurology
https://www.readbyqxmd.com/read/28121655/engaging-learners-in-health-system-quality-improvement-efforts
#8
Karnjit Johl, R Kevin Grigsby
In 1999, an Institute of Medicine report spurred health care organizations to implement systems-based quality improvement efforts and tackle patient safety. Simultaneously, the Accreditation Council for Graduate Medical Education asked residency programs to address Practice-Based Learning and Systems-Based Practice competencies. Medical educators now advocate incorporation of these competencies in undergraduate medical education.The authors examine the success of these efforts both from the health care delivery and systems perspective as well as from the perspective of educators as they aspire to engage medical students and residents in these domains...
January 24, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28117271/practical-quality-improvement-for-the-allergist-immunologist
#9
REVIEW
David W Price, David M Lang
Quality improvement (QI) has long been part of organized medicine, but has become increasingly more important in the last few years. Clinical expertise and input into QI activities are critical to keep QI grounded in evidence and practice. Busy clinicians face many competing demands; practical strategies are needed to help busy clinicians successfully engage in QI. This article provides a brief history of QI in medicine, notes several commonly used frameworks for QI in health care, and presents a practical QI model that can be applied to the clinical practice of allergy and immunology...
January 20, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28103979/-foreign-firms-and-dissemination-of-western-medicine-in-china-before-the-opium-war
#10
L P He, L Wang
From the beginning of the 19th century to the Opium War, by taking the advantages of free entering and departing China, and to protect themselves, the foreign firms introduced vaccination technique into China. This is the beginning of the introduction of western medicine to China. After 1807, following the arrival of protestant missionaries, foreign firms became the stronghold for the missionaries to conceal their missionary status so as to propagate the principles of Christianity. With the aid of the business firms employee's legal identity, the missionaries started their activities of delivering western medicines and practices...
November 28, 2016: Zhonghua Yi Shi za Zhi, Chinese Journal of Medical History
https://www.readbyqxmd.com/read/28088344/design-control-considerations-for-biologic-device-combination-products
#11
Dave Anderson, Roger Liu, J Anand Subramony, Jon Cammack
Combination products are therapeutic and diagnostic medical products that combine drugs, devices, and/or biological products with one another. Historically, biologics development involved identifying efficacious doses administered to patients intravenously or perhaps by a syringe. Until fairly recently, there has been limited focus on developing an accompanying medical device, such as a prefilled syringe or auto-injector, to enable easy and more efficient delivery. For the last several years, and looking forward, where there may be little to distinguish biologics medicines with relatively similar efficacy profiles, the biotechnology market is beginning to differentiate products by patient-focused, biologic-device based combination products...
January 11, 2017: Advanced Drug Delivery Reviews
https://www.readbyqxmd.com/read/28078356/-marketability-of-food-supplements-criteria-for-the-legal-assessment
#12
Evelyn Breitweg-Lehmann
To be placed on the market legally, food supplements have to meet national and European food law regulations. This is true for all substances used as well as for the labeling on the packaging of and the advertising for food supplements. The food business operator is responsible for its compliance with all regulations. Therefore, in this article, a concise step-by-step assessment is presented, covering all necessary legal requirements to market food supplements. Additionally, all steps are visualized in a flow chart...
January 11, 2017: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/28053064/scientific-knowledge-and-technology-animal-experimentation-and-pharmaceutical-development
#13
Lewis B Kinter, Joseph J DeGeorge
Human discovery of pharmacologically active substances is arguably the oldest of the biomedical sciences with origins >3500 years ago. Since ancient times, four major transformations have dramatically impacted pharmaceutical development, each driven by advances in scientific knowledge, technology, and/or regulation: (1) anesthesia, analgesia, and antisepsis; (2) medicinal chemistry; (3) regulatory toxicology; and (4) targeted drug discovery. Animal experimentation in pharmaceutical development is a modern phenomenon dating from the 20th century and enabling several of the four transformations...
December 2016: ILAR Journal
https://www.readbyqxmd.com/read/28048333/mo-a-209-01-aapm-journal-finances-facts-figures-and-fundamentals
#14
S Armato
: Scientific publishing is a major endeavor of the AAPM. Although publishing requires substantial resources, it has the potential to generate both reputation and revenue to further the missions of our society. The AAPM owns and publishes two journals: Medical Physics and the Journal of Applied Clinical Medical Physics (JACMP). Medical Physics, with the tagline "The international journal of medical physics research and practice," publishes research concerned with the application of physics and mathematics to the solution of problems in medicine and human biology, with an emphasis on theoretical and experimental approaches...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047682/mo-a-209-02-a-tale-of-two-journals-open-access-and-subscription-based-publications
#15
J Bourland
: Scientific publishing is a major endeavor of the AAPM. Although publishing requires substantial resources, it has the potential to generate both reputation and revenue to further the missions of our society. The AAPM owns and publishes two journals: Medical Physics and the Journal of Applied Clinical Medical Physics (JACMP). Medical Physics, with the tagline "The international journal of medical physics research and practice," publishes research concerned with the application of physics and mathematics to the solution of problems in medicine and human biology, with an emphasis on theoretical and experimental approaches...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047033/mo-a-209-03-a-look-ahead-stewarding-the-financial-future-of-aapm-journals
#16
M Svatos
: Scientific publishing is a major endeavor of the AAPM. Although publishing requires substantial resources, it has the potential to generate both reputation and revenue to further the missions of our society. The AAPM owns and publishes two journals: Medical Physics and the Journal of Applied Clinical Medical Physics (JACMP). Medical Physics, with the tagline "The international journal of medical physics research and practice," publishes research concerned with the application of physics and mathematics to the solution of problems in medicine and human biology, with an emphasis on theoretical and experimental approaches...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046257/mo-a-209-00-financial-perspectives-on-scientific-publishing
#17
Samuel Armato
: Scientific publishing is a major endeavor of the AAPM. Although publishing requires substantial resources, it has the potential to generate both reputation and revenue to further the missions of our society. The AAPM owns and publishes two journals: Medical Physics and the Journal of Applied Clinical Medical Physics (JACMP). Medical Physics, with the tagline "The international journal of medical physics research and practice," publishes research concerned with the application of physics and mathematics to the solution of problems in medicine and human biology, with an emphasis on theoretical and experimental approaches...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28027163/the-business-of-health-physics-jobs-in-a-changing-market
#18
Matthew P Moeller
The health physics profession was born abruptly when once rare and precious radioactive materials became commonplace. The technological advancements that triggered an industrial complex and ended World War II demanded radiation safety on an unprecedented scale. Until then, protective measures against radiation were largely absent in laboratories. Over the subsequent decades, health physicists began protecting people and the environment in a wide range of settings including medical, research, and industrial...
February 2017: Health Physics
https://www.readbyqxmd.com/read/28018550/risky-business-psychological-safety-and-the-risks-of-learning-medicine
#19
William E Bynum, Taha M Haque
No abstract text is available yet for this article.
December 2016: Journal of Graduate Medical Education
https://www.readbyqxmd.com/read/28017435/informing-vaccine-decision-making-a-strategic-multi-attribute-ranking-tool-for-vaccines-smart-vaccines-2-0
#20
Stacey Knobler, Karin Bok, Bruce Gellin
SMART Vaccines 2.0 software is being developed to support decision-making among multiple stakeholders in the process of prioritizing investments to optimize the outcomes of vaccine development and deployment. Vaccines and associated vaccination programs are one of the most successful and effective public health interventions to prevent communicable diseases and vaccine researchers are continually working towards expanding targets for communicable and non-communicable diseases through preventive and therapeutic modes...
December 22, 2016: Vaccine
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