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https://www.readbyqxmd.com/read/28711892/3-d-bioprinting-law-regulation-perspectives
#1
Vitalii Pashkov, Andrii Harkusha
INTRODUCTION: Achieved level of technical progress moves us closer and closer to practical use of 3-d bioprinting technologies in real life. Such perspective raise a wide variety of crucial legal issues from the acceptable model of regulation of the science and its' societal effects to problems of the commercialization of the technology and potential restrictions of its use. Some key points on concept of legal regulation of abovementioned sphere is a base of this study. MATERIAL AND METHODS: Scientific discussion on 3-D bioprinting, European Union`s and US experience in patenting of 3-D bioprinting technologies, European Medicine Agency (EMA) or the US Food and Drug Administration (FDA) regulations, European Medical Technology Industry Association (EUCOMED) Acts...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28710656/medicine-and-technology-remarks-on-the-notion-of-responsibility-in-the-technology-assisted-health-care
#2
Waldemar Kwiatkowski
The introduction of the modern diagnostic and therapeutic procedures to the medical practice provided a new challenge for the medicine. The art of medicine, with its default purpose of acting for the benefit of health, is therefore required to derive from technological progress effectively and rationally. As a result, the medical ethics has been engaged with the rules of economy and management of deficit medical procedures as well as their rational and fair distribution. The above suggests, that medics, given these recourses, should approach each patient with a consideration to their therapeutic rights...
July 14, 2017: Medicine, Health Care, and Philosophy
https://www.readbyqxmd.com/read/28699568/evaluation-of-the-informatician-perspective-determining-types-of-research-papers-preferred-by-clinicians
#3
Boshu Ru, Xiaoyan Wang, Lixia Yao
BACKGROUND: To deliver evidence-based medicine, clinicians often reference resources that are useful to their respective medical practices. Owing to their busy schedules, however, clinicians typically find it challenging to locate these relevant resources out of the rapidly growing number of journals and articles currently being published. The literature-recommender system may provide a possible solution to this issue if the individual needs of clinicians can be identified and applied...
July 5, 2017: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/28697744/e-learning-in-graduate-medical-education-survey-of-residency-program-directors
#4
Christopher M Wittich, Anoop Agrawal, David A Cook, Andrew J Halvorsen, Jayawant N Mandrekar, Saima Chaudhry, Denise M Dupras, Amy S Oxentenko, Thomas J Beckman
BACKGROUND: E-learning-the use of Internet technologies to enhance knowledge and performance-has become a widely accepted instructional approach. Little is known about the current use of e-learning in postgraduate medical education. To determine utilization of e-learning by United States internal medicine residency programs, program director (PD) perceptions of e-learning, and associations between e-learning use and residency program characteristics. METHODS: We conducted a national survey in collaboration with the Association of Program Directors in Internal Medicine of all United States internal medicine residency programs...
July 11, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28664271/-changes-in-the-german-medicinal-product-act-imposed-by-the-eu-regulation-on-clinical-trials
#5
REVIEW
Lars Nickel, Yvonne Seibel, Marion Frech, Thomas Sudhop
The entry into force of Regulation (EU) No. 536/2014 of the European Parliament, the Council of 16 April 2014 for clinical trials on medicinal products for human use, and repealing Directive 2001/20/EC necessitated amendments to the national legislation on medicinal products. These changes mainly concern the sixth chapter of the German Medicinal Products Act (Arzneimittelgesetz, AMG) and the elimination of the GCP (good clinical practice) ordinance for clinical trials that will be covered by the regulation in the future...
June 29, 2017: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/28661955/tablet-based-intervention-for-reducing-children-s-preoperative-anxiety-a-pilot-study
#6
Cheryl H T Chow, Ryan J Van Lieshout, Louis A Schmidt, Norman Buckley
OBJECTIVES: To examine the feasibility, acceptability, and effects of a novel tablet-based application, Story-Telling Medicine (STM), in reducing children's preoperative anxiety. METHODS: Children (N = 100) aged 7 to 13 years who were undergoing outpatient surgery were recruited from a local children's hospital. This study comprised 3 waves: Waves 1 (n = 30) and 2 (n = 30) examined feasibility, and Wave 3 (n = 40) examined the acceptability of STM and compared its effect on preoperative anxiety to Usual Care (UC)...
July 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28661111/-at-the-crossroads-the-role-of-laboratory-medicine-in-the-patient-care-process
#7
REVIEW
Yuval Geffen, Itzhak Zaidise
In recent decades, the laboratory medicine profession has undergone significant changes due to both technological developments and economic constraints. Technological innovations support automation, provide faster and more accurate equipment, and allow increased efficiency through the use of commercial test kits. These changes, combined with budgetary constraints, have led to mergers and centralization of medical laboratories to optimize work and cut costs. While this centralization may be a business necessity, it leads to a disconnection between the laboratory and the clinical context...
June 2017: Harefuah
https://www.readbyqxmd.com/read/28659071/using-systems-thinking-in-patient-safety-a-case-study-on-medicines-management
#8
Mandy Brimble, Aled Jones
Systems thinking is used as a way of understanding behaviours and actions in complex healthcare organisations. An important premise of the concept is that every action in a system causes a reaction elsewhere in that system. These reactions can lead to unintended consequences, sometimes long after the original action, and so are not always attributed to them. This article applies systems thinking to a medicines management case study, to highlight how quality-improvement practitioners can use the approach to underpin planning and implementation of patient-safety initiatives...
June 29, 2017: Nursing Management (Harrow)
https://www.readbyqxmd.com/read/28651620/an-assessment-of-the-factors-affecting-the-commercialization-of-cell-based-therapeutics-a-systematic-review-protocol
#9
David Pettitt, Zeeshaan Arshad, Benjamin Davies, James Smith, Anna French, Doug Cole, Kim Bure, Sue Dopson, David DiGiusto, Jeff Karp, Brock Reeve, Richard Barker, Georg Holländer, David Brindley
BACKGROUND: Cellular-based therapies represent a platform technology within the rapidly expanding field of regenerative medicine and are distinct from conventional therapeutics-offering a unique approach to managing what were once considered untreatable diseases. Despite a significant increase in basic science activity within the cell therapy arena, alongside a growing portfolio of cell therapy trials and promising investment, the translation of cellular-based therapeutics from "bench to bedside" remains challenging, and the number of industry products available for widespread clinical use remains comparatively low...
June 26, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28639040/mobile-gastrointestinal-and-endoscopic-surgery-in-rural-ecuador-20%C3%A2-years-experience-of-cinterandes
#10
H T Shalabi, M D Price, S T Shalabi, E B Rodas, A L Vicuña, B Guzhñay, R R Price, E Rodas
INTRODUCTION: Five billion people worldwide do not have timely access to surgical care. Cinterandes is one of the only mobile surgical units in low- and middle-income countries. This paper examines the methodology that Cinterandes uses to deliver mobile surgery. METHODS: Founding and core staff were interviewed, four missions were participated in, and internal documents and records were analysed between 1 May and 1 July 2014. RESULTS: Cinterandes performed 7641 operations over the last 20 years (60% gastrointestinal/laparoscopic), travelling 300,000 km to remote areas of Ecuador...
June 21, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28529529/disclosure-of-traditional-and-complementary-medicine-use-and-its-associated-factors-to-medical-doctor-in-primary-care-clinics-in-kuching-division-sarawak-malaysia
#11
Anak Kelak Johny, Whye Lian Cheah, Safii Razitasham
The decision by the patients to disclose traditional and complementary medicine (TCM) use to their doctor is an important area to be explored. This study aimed to determine the disclosure of TCM use and its associated factors to medical doctor among primary care clinic attendees in Kuching Division, Sarawak. It was a cross-sectional study using questionnaire, interviewer administered questionnaire. A total of 1130 patients were screened with 80.2% reporting using TCM. Logistic regression analysis revealed that being female (AOR = 3...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28525630/laboratory-integration-and-consolidation-in-a-regional-health-system
#12
Jim Cook
Health systems face intense pressure to decrease costs and improve services as the health care delivery system in the United States undergoes tremendous change due to health care reform. As health systems grow, like any business, they are forced to explore standardization to realize and maintain efficient practices. Clinical services, such as laboratory medicine, are more difficult to integrate due to wider variation in acceptable practice and culture, compared with other services. However, changes to laboratory service are imperative if health care professionals expect to survive and thrive in the new business environment...
May 19, 2017: Laboratory Medicine
https://www.readbyqxmd.com/read/28512360/bullying-behavior-and-mental-health-in-healthcare-and-educational-sectors-in-kaunas-lithuania
#13
Lina Bernotaite, Vilija Malinauskiene, Palmira Leisyte
BACKGROUND: Investigations on workplace bullying in the countries of Eastern Europe are yet not too extensive. The aim of the study has been to identify the most frequent bullying behavior and to explore the associations with psychological distress and post-traumatic stress symptoms in 3 female-dominated occupations in Kaunas, Lithuania. MATERIAL AND METHODS: This crosssectional study employed 517 teachers (response rate (RR) = 71.3%), 174 family physicians (RR = 65...
May 16, 2017: Medycyna Pracy
https://www.readbyqxmd.com/read/28508782/the-use-of-restful-web-services-in-medical-informatics-and-clinical-research-and-its-implementation-in-europe
#14
Jozef Aerts
BACKGROUND: RESTful web services nowadays are state-of-the-art in business transactions over the internet. They are however not very much used in medical informatics and in clinical research, especially not in Europe. OBJECTIVES: To make an inventory of RESTful web services that can be used in medical informatics and clinical research, including those that can help in patient empowerment in the DACH region and in Europe, and to develop some new RESTful web services for use in clinical research and regulatory review...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28506152/a-participatory-systems-approach-to-design-for-safer-integrated-medicine-management
#15
Gyuchan Thomas Jun, Aneurin Canham, Ander Altuna-Palacios, James R Ward, Ran Bhamra, Stephen Rogers, Amalin Dutt, Priyal Shah
It is recognised that whole systems approaches are required in the design and development of complex health care services. Application of a systems approach benefits from the involvement of key stakeholders. However, participation in the context of community based health care is particularly challenging due to busy and geographically distributed stakeholders. This study used action research to investigate what processes and methods were needed to successfully employ a participatory systems approach. Three participatory workshops planned and facilitated by method experts were held with 30 representative stakeholders...
June 2, 2017: Ergonomics
https://www.readbyqxmd.com/read/28504472/thoughtflow-standards-and-tools-for-provenance-capture-and-workflow-definition-to-support-model-informed-drug-discovery-and-development
#16
J J Wilkins, Pls Chan, J Chard, G Smith, M K Smith, M Beer, A Dunn, C Flandorfer, C Franklin, R Gomeni, L Harnisch, R Kaye, S Moodie, M L Sardu, E Wang, E Watson, K Wolstencroft, Sya Cheung
Pharmacometric analyses are complex and multifactorial. It is essential to check, track, and document the vast amounts of data and metadata that are generated during these analyses (and the relationships between them) in order to comply with regulations, support quality control, auditing, and reporting. It is, however, challenging, tedious, error-prone, and time-consuming, and diverts pharmacometricians from the more useful business of doing science. Automating this process would save time, reduce transcriptional errors, support the retention and transfer of knowledge, encourage good practice, and help ensure that pharmacometric analyses appropriately impact decisions...
May 2017: CPT: Pharmacometrics & Systems Pharmacology
https://www.readbyqxmd.com/read/28502910/balancing-volume-and-duration-of-information-consumption-by-physicians-the-case-of-health-information-exchange-in-critical-care
#17
Liran Politi, Shlomi Codish, Iftach Sagy, Lior Fink
BACKGROUND: The realization of the potential benefits of health information exchange systems (HIEs) for emergency departments (EDs) depends on the way these systems are actually used. The attributes of volume of information and duration of information processing are important for the study of HIE use patterns in the ED, as cognitive load and time constraints may result in a trade-off between these attributes. Experts and non-experts often use different problem-solving strategies, which may be consequential for their system use patterns...
July 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28474422/determination-of-antioxidant-potential-of-acacia-nilotica-leaf-extract-in-oxidative-stress-response-system-of-saccharomyces-cerevisiae
#18
Subhaswaraj Pattnaik, Sowmya Mani, Jobina Rajkumari, Sudharshan Sj, Madhu Dyavaiah, Siddhardha Busi
BACKGROUND: From ancient times, plants and plant derived products are used as folkloric medicines in a variety of health disorders owing to their tremendous therapeutic potential. The present study aims to determine the antioxidant efficacy of crude Acacia nilotica extract in oxidative stress response system of Saccharomyces cerevisiae as model organism. RESULTS: A. nilotica showed significant antioxidant activity with an IC50 value of 75.157 and 159.57 µg mL(-1) for DPPH radical and hydroxyl radical scavenging activity respectively at a concentration of 500 µg mL(-1) ...
May 5, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28468023/islamic-civilization-in-spain-a-magnificient-example-of-interaction-and-unity-of-religion-and-science
#19
Safvet Halilović
Islam and its followers had created a civilization that played very important role on the world stage for more than a thousand years. One of the most important specific qualities of the Islamic civilization is that it is a well-balanced civilization that brought together science and faith, struck a balance between spirit and matter and did not separate this world from the Hereafter. This is what distinguishes the Islamic civilization from other civilizations which attach primary importance to the material aspect of life, physical needs and human instincts, and attach greater attention to this world by striving to instantly satisfy desires of the flesh, without finding a proper place for God and the Hereafter in their philosophies and education systems...
April 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/28464172/initial-experience-of-a-primary-urgent-care-clinic-curriculum-and-subspecialty-lectureship-series-implementation-in-a-los-angeles-county-hospital
#20
Harsh Agrawal, Anna Martinez, Elizabeth R Volkmann, Oleg Melamed, Soma Wali
OBJECTIVES: Urgent care clinics are extremely busy in the University of California-Los Angeles (UCLA) County hospital system. We determined that residents and medical students in the internal medicine residency program who are rotating through these clinics did not receive enough teaching during their rotation. We decided to create and implement an urgent care curriculum and lectures to help achieve structure for the rotation. The goal of this series was to educate and assist residents in the primary care setting to comfortably manage subspecialty conditions, help reduce the already-overwhelmed county subspecialty referral system, and promote learning...
May 2017: Southern Medical Journal
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