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hyperlipidemic acute pancreatitis

Lixin Yang, Jing Liu, Yun Xing, Lichuan Du, Jing Chen, Xin Liu, Jianyu Hao
Hyperlipidemic acute pancreatitis (HLAP) is characterized by critical condition and high recurrence rate compared with non-HLAP. We conducted this study to investigate the value of body mass index and waist-hip ratio in predicting severity and local complications in HLAP. 96 patients with HLAP were categorized by body mass index and waist-hip ratio, respectively. According to the body mass index, they were divided into 3 groups, including normal weight, overweight, and obesity. According to the waist-hip ratio, they were divided into central obesity group and no central obesity group...
2017: Gastroenterology Research and Practice
Yin Zhu, Xiaolin Pan, Hao Zeng, Wenhua He, Liang Xia, Pi Liu, Yong Zhu, Youxiang Chen, Nonghua Lv
OBJECTIVES: Currently, the epidemiology of acute pancreatitis (AP) according to the Atlanta classification 2012 is rare. Thus, we aim to evaluate the etiology, severity, and mortality of AP according to Atlanta classification 2012 in Jiangxi, China. METHODS: We analyzed 3260 hospitalized patients between 2005 and 2012 from AP database. The severity was classified by the Atlanta classification 2012. RESULTS: 3260 patients were admitted. Cholelithiasis (58...
April 2017: Pancreas
Annika Charlesworth, Adrian Steger, Martin A Crook
No abstract text is available yet for this article.
January 2017: Pancreas
Lixin Yang, Jing Liu, Yun Xing, Lichuan Du, Jing Chen, Xin Liu, Jianyu Hao
In recent years, with the developing of living standard, hyperlipidemia becomes the second major reason of acute pancreatitis. It is important to predict the severity and prognosis at early stage of hyperlipidemic acute pancreatitis (HLAP). We compared the BISAP, Ranson, MCTSI, and APACHE II scoring system in predicting MSAP and SAP, local complications, and mortality of HLAP. A total of 326 diagnosed hyperlipidemic acute pancreatitis patients from August 2006 to July 2015 were studied retrospectively. Our result showed that all four scoring systems can be used to predict the severity, local complications, and mortality of HLAP...
2016: Gastroenterology Research and Practice
L X Yang, L C Du, X Liu, J Chen, J Y Hao
OBJECTIVE: To explore the four criteria, including bedside index for severity in acute pancreatitis(BISAP), Ranson score, modified CT severity index(MCTSI) and acute physiology and chronic health evaluation scoring systemⅡ(APACHE Ⅱ) in assessment of severity and prognosis of hyperlipidemic acute pancreatitis. METHODS: A total of 326 patients with hyperlipidemic acute pancreatitis were studied retrospectively from August 2006 to July 2015. The discrepancy of the four criteria in assessment of severity and prognosis of hyperlipidemic acute pancreatitis was compared with chi-square test and receiver operating characteristic curve...
September 1, 2016: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
Tiffany J Patton, Timothy A Sentongo, Grace Z Mak, Stacy A Kahn
Here we report the case of a 4-year-old male with severe acute pancreatitis due to hyperlipidemia, who presented with abdominal pain, metabolic abnormalities, and colonic necrosis. This colonic complication was secondary to the extension of a large peripancreatic fluid collection causing direct serosal autodigestion by pancreatic enzymes. Two weeks following the initial presentation, the peripancreatic fluid collection developed into a mature pancreatic pseudocyst, which was percutaneously drained. To our knowledge, this is the youngest documented pediatric case of colonic necrosis due to severe pancreatitis and the first descriptive pediatric case of a colonic complication due to hyperlipidemia-induced acute pancreatitis...
2016: Case Reports in Pediatrics
Danilo Di Bona, Angelo B Cefalù, Elisabetta Scirè, Giacomo M Lima, Claudia Maria Rizzo, Antonina Giammanco, Carlo M Barbagallo, Maurizio R Averna, Sergio Rizzo, Calogero Caruso
BACKGROUND: Chylomicronemia syndrome is a metabolic condition characterized by severe fasting hypertrigliceridemia (≥ 1000 mg/dL) and other clinical features including chronic abdominal pain and recurrent acute pancreatitis. In patients with acute or recurrent pancreatitis, plasma exchange (PEx) is indicated for the treatment of acute disease and prevention of recurrence. The use of plasma instead of albumin as replacement fluid has been suggested for its putative ability to replace the deficient enzyme possibly leading to better clinical improvement...
March 2016: Transfusion
Shiren Sun, Lijie He, Ming Bai, Hongbao Liu, Yangping Li, Li Li, Yan Yu, Meilan Shou, Rui Jing, Liyuan Zhao, Chen Huang, Hanmin Wang
BACKGROUND AND OBJECTIVES: The evidence for high-volume hemofiltration plus hemoperfusion (HVHF&HP) for hyperlipidemic severe acute pancreatitis (HL-SAP) is anecdotal. The purpose of our study was to evaluate the efficacy of HVHF&HP for HL-SAP in a prospective controlled study. DESIGN AND SETTING: Prospective controlled pilot study between May 2010 and May 2013 in a hospital intensive care unit. PATIENTS AND METHODS: HL-SAP patients chose conventional treatment alone (the control group) or conventional treatment combined with the experimental protocol (the HVHF&HP group) and were prospectively followed in our hospital...
September 2015: Annals of Saudi Medicine
Guojian Yin, Xiaofeng Cang, Ge Yu, Guoyong Hu, Jianbo Ni, Jie Xiong, Yanling Hu, Miao Xing, Congying Chen, Yinshi Huang, Maochun Tang, Yan Zhao, Guilian Cheng, Rong Wan, Shaofeng Wang, Xingpeng Wang
OBJECTIVES: The goal of this study was to summarize the clinical features of hyperlipidemic acute pancreatitis (HLAP), and help clinicians understand the characteristic presentations of HLAP. METHODS: From July 2009 to June 2013, 1073 cases of acute pancreatitis were retrospectively assessed. The clinical characteristics of HLAP and non-HLAP were statistically analyzed. RESULTS: The etiologic ratio of HLAP in acute pancreatitis rose from 13% in 2009 to 25...
October 2015: Pancreas
Yu-Ting Chang, Ming-Chu Chang, Chien-Chih Tung, Shu-Chen Wei, Jau-Min Wong
AIM: To investigate how the saturated and unsaturated fatty acid composition influences the susceptibility of developing acute pancreatitis. METHODS: Primary pancreatic acinar cells were treated with low and high concentrations of different saturated and unsaturated fatty acids, and changes in the cytosolic Ca(2+) signal and the expression of protein kinase C (PKC) were measured after treatment. RESULTS: Unsaturated fatty acids at high concentrations, including oleic acid, linoleic acid, palmitoleic acid, docosahexaenoic acid, and arachidonic acid, induced a persistent rise in cytosolic Ca(2+) concentrations in acinar cells...
August 28, 2015: World Journal of Gastroenterology: WJG
Amutijiang Mahemuti, Abudoushalamu Abudoureyimu, Ge Chen
OBJECTIVE: To investigate the clinical features and plasmapheresis treatment outcome of hyperlipidemic acute pancreatitis among Uyghur population. METHODS: The clinical data of 41 cases (treatment group) diagnosed with acute hyperlipidemic pancreatitis and treated with plasmapheresis from August 2007 to August 2012 was studied, and treatment outcomes were statistically analyzed. Fifty patients during the same period who received medical treatment without plasmapheresis (control group) were collected, and were compared to the treatment group...
March 2015: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
Lei Qiu, Rui Qing Sun, Rong Rong Jia, Xiu Ying Ma, Li Cheng, Mao Chun Tang, Yan Zhao
It is important to identify the severity of acute pancreatitis (AP) in the early course of the disease. Clinical scoring systems may be helpful to predict the prognosis of patients with early AP; however, few analysts have forecast the accuracy of scoring systems for the prognosis in hyperlipidemic acute pancreatitis (HLAP). The purpose of this study was to summarize the clinical characteristics of HLAP and compare the accuracy of conventional scoring systems in predicting the prognosis of HLAP. This study retrospectively analyzed all consecutively diagnosed AP patients between September 2008 and March 2014...
June 2015: Medicine (Baltimore)
Hong-Liang Wang, Kai-Jiang Yu
AIM: To evaluate the efficacy of sequential blood purification therapy in the treatment of critical patients with hyperlipidemic severe acute pancreatitis. METHODS: Thirty-one intensive care unit (ICU) patients with hyperlipidemic severe acute pancreatitis treated at the Second Affiliated Hospital of Harbin Medical University were divided into either a study group (n = 15; July 1, 2012 to June 30, 2014) or a control group (n = 16; July 1, 2010 to June 30, 2012) based on the implementation of sequential blood purification therapy...
May 28, 2015: World Journal of Gastroenterology: WJG
Lihua Guo, Tuo Zheng, Guimei Hu, Jinfeng Wen, Xueyou Lv, Biqing Yan, Guoliang Ye
No abstract text is available yet for this article.
October 2015: Therapeutic Apheresis and Dialysis
Mehmet Sait Buğdacı, Ali Tüzün, Harun Koca, Turhan Çavusoğlu, Ümit Akyüz, Hakan Şentürk
BACKGROUND/AIMS: QT dispersion is a sign of heterogeneity of ventricular myocardial wall and is associated with cardiac mortality and morbidity. Data regarding with the persistence of QT interval changes in cases with acute pancreatitis (AP) that required clinical follow-up, are insufficient. Therefore, in this study, we aimed to evaluate the QT interval changes during attack and after remission of the disease, in cases with AP. MATERIALS AND METHODS: The cases admitted to the Gastroenterohepatology Clinic with the diagnosis of AP were included into the study...
December 2014: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
Serhat Akay, Murat Enis Ardic, Nazif Erkan
Hypertriglyceridemia is a well established cause of acute pancreatitis (AP). Multiple mechanism are proposed to explain this phenomenon, but the exact mechanism is unknown. Clinical manifestations are similar to other forms of AP. Although amylase and lipase levels exclude the diagnosis of AP in normolipidemic patients, they may be normal in hypertriglyceridemia-induced AP. Further evaluation with imaging studies are needed for diagnosis. A less known entity "hyperlipidemic abdominal crisis" is a prior clinical state before development to AP...
August 2011: Eurasian Journal of Medicine
Haifeng Xu, Yong Li, Jun Yan, Yan Cai, Hongfeng Yang, Jing Liu, Qingyan Zhang, Musen Ji, Jie Lu, Jingrong Zou, Zhaochen Jin
OBJECTIVE: To explore the relationship between etiology and severity of acute pancreatitis (AP). METHODS: A total of 486 AP patients, hospitalized at digestive, general surgery or critical care medicine departments from May 2012 to May 2014, were recruited retrospectively. And the data of clinical features, etiology and severity classification of AP according to the revised Atlanta criteria (2012) were collected. The relationships between different gender, age group, etiology and severity of disease were compared...
November 11, 2014: Zhonghua Yi Xue za Zhi [Chinese medical journal]
A Markota, M Knehtl, A Sinkovic, R Ekart, R Hojs, S Bevc
Hypertriglyceridemia is a well-recognized cause of acute pancreatitis. We present a patient with acute hypertriglyceridemic pancreatitis. At presentation serum triglycerides were severely elevated (104 mmol/l) and were decreasing the next day (11 mmol/l). However, based on increasing levels of serum lipase, worsening respiratory failure and evidently lipemic serum, we decided to perform plasma exchange, and patient's condition improved dramatically. Repeated laboratory test of the serum obtained before the first plasma exchange revealed that the actual value of serum triglycerides was 57 mmol/l...
October 2014: Transfusion and Apheresis Science
Ying Hang, Yi Chen, Li-Xiong Lu, Chang-Qing Zhu
BACKGROUND: Acute pancreatitis is a serious complication during pregnancy, however the incidence of hyperlipidemia induced by pancreatitis is lower. METHODS: We treated a pregnant woman with hypertriglyceridemia-associated acute gestational pancreatitis who simultaneously developed hypoxemic acute respiratory failure (ARF). RESULTS: The woman was successfully treated through noninvasive positive pressure ventilation (NPPV), emergent caesarean delivery, drainage of chylous ascites, and peritoneal lavage...
2013: World Journal of Emergency Medicine
Yi Yun Deng, Rui Wang, Hao Wu, Cheng Wei Tang, Xin Zu Chen
OBJECTIVE: To study the etiology and clinical features of acute recurrent pancreatitis (ARP) and to determine its optimal management and outcomes. METHODS: ARP cases among acute pancreatitis patients who were admitted to the West China Hospital, Sichuan University from January 2008 to December 2012 were retrospectively collected. Their etiology, clinical features, treatments and outcomes were analyzed. RESULTS: Of all pancreatitis patients, 8...
October 2014: Journal of Digestive Diseases
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