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hyperlipidemic acute pancreatitis

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https://www.readbyqxmd.com/read/29658450/-influence-of-acute-pancreatitis-in-pregnancy-on-pregnancy-outcomes-and-neonates
#1
Shu-Juan Fan, Jun-Xi Xiang, Mi Xiao, Fang-Hui Wang, Xiao-Jie Lin, Xi-Hui Zhou, Ting Ai, Li Liu
OBJECTIVE: To study the influence of acute pancreatitis in pregnancy (APIP) on pregnancy outcomes and neonates. METHODS: A retrospective analysis was performed for 33 APIP patients and 31 neonates born alive. RESULTS: Of the 33 APIP patients, 26 (79%) developed APIP in the late pregnancy. Fourteen (45%) patients had hyperlipidemic APIP, 13 (42%) had biliary APIP, and 4 (13%) had other types of APIP. According to the severity, 22 (67%) were mild APIP, 5 (15%) were moderate APIP, and 6 were severe APIP...
April 2018: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29479871/the-relationship-between-trypsin-calcitonin-gene-related-peptide-cgrp-in-serum-and-acute-pancreatitis-ap
#2
Jianxiong Hu, Wei Lin, Chengfei Zhao, Jianfang Chen
BACKGROUND: Activation of trypsin from proteolytic cleavage of trypsinogen in the pancreas can lead to acute pancreatitis. Calcitonin gene related peptide (CGRP) from both peripheral and central neurons is involved in a variety of physiological/pathophysiological processes, especially sensory (nociceptive) and efferent (effector) functions. To better understand the change of trypsin/CGRP in acute pancreatitis, the study investigated the serum level of trypsin/CGRP in patients with acute pancreatitis...
January 1, 2018: Clinical Laboratory
https://www.readbyqxmd.com/read/29443736/what-may-cause-fetus-loss-from-acute-pancreatitis-in-pregnancy-analysis-of-54-cases
#3
MULTICENTER STUDY
Min Tang, Jian-Ming Xu, Sha-Sha Song, Qiao Mei, Li-Jiu Zhang
Acute pancreatitis in pregnancy (APIP) poses a serious threat to the mother and her fetus, and might lead to fetal loss including miscarriage and stillbirth in certain patients. We sought to identify possible factors that affect fetal distress and evaluated outcomes of patients with APIP.We retrospectively reviewed clinical records of 54 pregnant women with APIP, who were treated at 2 tertiary clinical centers over a 6-year period. Clinical characteristics including etiology and severity of APIP, fetal monitoring data, and maternofetal outcomes were analyzed...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29409663/penta-therapy-for-severe-acute-hyperlipidemic-pancreatitis-a-retrospective-chart-review-over-a-10-year-period
#4
Jian Lu, Yun Xie, Jiang Du, Mei Kang, Wei Jin, Yan Li, Hui Xie, Ruijie Cheng, Rui Tian, Ruilan Wang
INTRODUCTION: The purpose of our study is to evaluate the efficacy of penta-therapy for HL-SAP in a retrospective study. METHODS: Retrospective study between January 2007 and December 2016 in a hospital intensive care unit. HL-SAP patients were assigned to conventional treatment alone (the control group) or conventional treatment with the experimental protocol (the penta-therapy group) consists of blood purification, antihyperlipidemic agents, low-molecular weight heparin, insulin, covering the whole abdomen with Pixiao (a traditional Chinese medicine)...
February 3, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29103458/pomegranate-leaf-attenuates-lipid-absorption-in-the-small-intestine-in-hyperlipidemic-mice-by-inhibiting-lipase-activity
#5
Xuan Yu, Xin-Pei Wang, Fan Lei, Jing-Fei Jiang, Jun Li, Dong-Ming Xing, Li-Jun DU
Pomegranate leaf (PGL) has a definite role in regulating lipid metabolism. However, pharmacokinetic results show the main active ingredient, ellagic acid, in PGL has lower oral bioavailability, suggesting that the lipid-lowering effect of PGL may act through inhibiting lipid absorption in the small intestine. Our results demonstrated that pomegranate leaf and its main active ingredients (i.e., ellagic acid, gallic acid, pyrogallic acid and tannic acid) were capable of inhibiting pancreatic lipase activity in vitro...
October 2017: Chinese Journal of Natural Medicines
https://www.readbyqxmd.com/read/29068376/a-mini-review-on-the-effect-of-docosahexaenoic-acid-dha-on-cerulein-induced-and-hypertriglyceridemic-acute-pancreatitis
#6
REVIEW
Yoo Kyung Jeong, Hyeyoung Kim
Acute pancreatitis refers to the sudden inflammation of the pancreas. It is associated with premature activation and release of digestive enzymes into the pancreatic interstitium and systemic circulation, resulting in pancreatic tissue autodigestion and multiple organ dysfunction, as well as with increased cytokine production, ultimately leading to deleterious local and systemic effects. Although mechanisms involved in pathogenesis of acute pancreatitis have not been completely elucidated, oxidative stress is regarded as a major risk factor...
October 25, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28826568/acute-hyperlipidemic-pancreatitis-accompanied-by-chylous-ascites-with-normal-amylase-and-lipase-in-pregnancy
#7
Li Yang, Zhiguo Zhao, Kaiming Zhou, Yuling Zhang
Normal serum amylase is uncommon even in acute hypertriglyceridemic pancreatitis (HTGAP). However, normal serum lipase and amylase activity in HTGAP with chylous ascites is exceptionally rare. We report a pregnant woman with HTGAP and chylous ascites that were misdiagnosed. She showed acute abdominal pain and significant systemic inflammatory response, but her serum amylase and lipase levels failed to increase, although ultrasonic imaging finding of the pancreas was normal. Early clinical recognition of chylomicronemia helps clinicians diagnose HTGAP rapidly during pregnancy...
July 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/28669771/antidiabetic-antioxidant-and-anti-inflammatory-properties-of-water-and-n-butanol-soluble-extracts-from-saharian-anvillea-radiata-in-high-fat-diet-fed-mice
#8
COMPARATIVE STUDY
Chouaib Kandouli, Mathieu Cassien, Anne Mercier, Caroline Delehedde, Emilie Ricquebourg, Pierre Stocker, Mourad Mekaouche, Zineb Leulmi, Aicha Mechakra, Sophie Thétiot-Laurent, Marcel Culcasi, Sylvia Pietri
ETHNOPHARMACOLOGICAL RELEVANCE: According to Saharian traditional medicine, Anvillea radiata Coss. & Dur. (Asteraceae) has been valued for treating a variety of ailments such as gastro-intestinal, liver and pulmonary diseases, and has gained awareness for its beneficial effect on postprandial hyperglycemia. However, to best of our knowledge, no detailed study of the antidiabetic curative effects of this plant has been conducted yet. AIM OF THE STUDY: To determine the hypoglycemic and antidiabetic effect of dietary supplementation with Anvillea radiata extracts on high-fat-diet (HFD)-induced obesity and insulin resistance in C57BL/6J mice in relation with antioxidant, anti-inflammatory, pancreatic beta-cells and skeletal muscle protection, and digestive enzyme inhibiting properties...
July 31, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28479718/potential-lipid-lowering-effects-of-eleusine-indica-l-gaertn-extract-on-high-fat-diet-induced-hyperlipidemic-rats
#9
Siew Ling Ong, Koteswara Rao Nalamolu, How Yee Lai
BACKGROUND: To date, anti-obesity agents based on natural products are tested for their potential using lipase inhibition assay through the interference of hydrolysis of fat by lipase resulting in reduced fat absorption without altering the central mechanisms. Previous screening study had indicated strong anti-obesity potential in Eleusine indica (E. indica), but to date, no pharmacologic studies have been reported so far. OBJECTIVE: This study was performed to investigate the lipid-lowering effects of E...
January 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28331492/correlation-of-body-mass-index-and-waist-hip-ratio-with-severity-and-complications-of-hyperlipidemic-acute-pancreatitis-in-chinese-patients
#10
Lixin Yang, Jing Liu, Yun Xing, Lichuan Du, Jing Chen, Xin Liu, Jianyu Hao
Hyperlipidemic acute pancreatitis (HLAP) is characterized by critical condition and high recurrence rate compared with non-HLAP. We conducted this study to investigate the value of body mass index and waist-hip ratio in predicting severity and local complications in HLAP. 96 patients with HLAP were categorized by body mass index and waist-hip ratio, respectively. According to the body mass index, they were divided into 3 groups, including normal weight, overweight, and obesity. According to the waist-hip ratio, they were divided into central obesity group and no central obesity group...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28196012/a-study-on-the-etiology-severity-and-mortality-of-3260-patients-with-acute-pancreatitis-according-to-the-revised-atlanta-classification-in-jiangxi-china-over-an-8-year-period
#11
Yin Zhu, Xiaolin Pan, Hao Zeng, Wenhua He, Liang Xia, Pi Liu, Yong Zhu, Youxiang Chen, Nonghua Lv
OBJECTIVES: Currently, the epidemiology of acute pancreatitis (AP) according to the Atlanta classification 2012 is rare. Thus, we aim to evaluate the etiology, severity, and mortality of AP according to Atlanta classification 2012 in Jiangxi, China. METHODS: We analyzed 3260 hospitalized patients between 2005 and 2012 from AP database. The severity was classified by the Atlanta classification 2012. RESULTS: 3260 patients were admitted. Cholelithiasis (58...
April 2017: Pancreas
https://www.readbyqxmd.com/read/27977632/hyperlipidemic-acute-pancreatitis-and-the-apolipoprotein-e4-allele
#12
Annika Charlesworth, Adrian Steger, Martin A Crook
No abstract text is available yet for this article.
January 2017: Pancreas
https://www.readbyqxmd.com/read/27882045/comparison-of-bisap-ranson-mctsi-and-apache-ii-in-predicting-severity-and-prognoses-of-hyperlipidemic-acute-pancreatitis-in-chinese-patients
#13
Lixin Yang, Jing Liu, Yun Xing, Lichuan Du, Jing Chen, Xin Liu, Jianyu Hao
In recent years, with the developing of living standard, hyperlipidemia becomes the second major reason of acute pancreatitis. It is important to predict the severity and prognosis at early stage of hyperlipidemic acute pancreatitis (HLAP). We compared the BISAP, Ranson, MCTSI, and APACHE II scoring system in predicting MSAP and SAP, local complications, and mortality of HLAP. A total of 326 diagnosed hyperlipidemic acute pancreatitis patients from August 2006 to July 2015 were studied retrospectively. Our result showed that all four scoring systems can be used to predict the severity, local complications, and mortality of HLAP...
2016: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/27586977/-the-role-of-four-criteria-in-assessment-of-the-severity-and-prognosis-of-hyperlipidemic-acute-pancreatitis
#14
L X Yang, L C Du, X Liu, J Chen, J Y Hao
OBJECTIVE: To explore the four criteria, including bedside index for severity in acute pancreatitis(BISAP), Ranson score, modified CT severity index(MCTSI) and acute physiology and chronic health evaluation scoring systemⅡ(APACHE Ⅱ) in assessment of severity and prognosis of hyperlipidemic acute pancreatitis. METHODS: A total of 326 patients with hyperlipidemic acute pancreatitis were studied retrospectively from August 2006 to July 2015. The discrepancy of the four criteria in assessment of severity and prognosis of hyperlipidemic acute pancreatitis was compared with chi-square test and receiver operating characteristic curve...
September 1, 2016: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/26925282/colonic-necrosis-in-a-4-year-old-with-hyperlipidemic-acute-pancreatitis
#15
Tiffany J Patton, Timothy A Sentongo, Grace Z Mak, Stacy A Kahn
Here we report the case of a 4-year-old male with severe acute pancreatitis due to hyperlipidemia, who presented with abdominal pain, metabolic abnormalities, and colonic necrosis. This colonic complication was secondary to the extension of a large peripancreatic fluid collection causing direct serosal autodigestion by pancreatic enzymes. Two weeks following the initial presentation, the peripancreatic fluid collection developed into a mature pancreatic pseudocyst, which was percutaneously drained. To our knowledge, this is the youngest documented pediatric case of colonic necrosis due to severe pancreatitis and the first descriptive pediatric case of a colonic complication due to hyperlipidemia-induced acute pancreatitis...
2016: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/26536493/albumin-versus-solvent-detergent-treated-pooled-plasma-as-replacement-fluid-for-long-term-plasma-exchange-therapy-in-a-patient-with-primary-hypertriglyceridemia-and-recurrent-hyperlipidemic-pancreatitis
#16
Danilo Di Bona, Angelo B Cefalù, Elisabetta Scirè, Giacomo M Lima, Claudia Maria Rizzo, Antonina Giammanco, Carlo M Barbagallo, Maurizio R Averna, Sergio Rizzo, Calogero Caruso
BACKGROUND: Chylomicronemia syndrome is a metabolic condition characterized by severe fasting hypertrigliceridemia (≥ 1000 mg/dL) and other clinical features including chronic abdominal pain and recurrent acute pancreatitis. In patients with acute or recurrent pancreatitis, plasma exchange (PEx) is indicated for the treatment of acute disease and prevention of recurrence. The use of plasma instead of albumin as replacement fluid has been suggested for its putative ability to replace the deficient enzyme possibly leading to better clinical improvement...
March 2016: Transfusion
https://www.readbyqxmd.com/read/26506968/high-volume-hemofiltration-plus-hemoperfusion-for-hyperlipidemic-severe-acute-pancreatitis-a-controlled-pilot-study
#17
Shiren Sun, Lijie He, Ming Bai, Hongbao Liu, Yangping Li, Li Li, Yan Yu, Meilan Shou, Rui Jing, Liyuan Zhao, Chen Huang, Hanmin Wang
BACKGROUND AND OBJECTIVES: The evidence for high-volume hemofiltration plus hemoperfusion (HVHF&HP) for hyperlipidemic severe acute pancreatitis (HL-SAP) is anecdotal. The purpose of our study was to evaluate the efficacy of HVHF&HP for HL-SAP in a prospective controlled study. DESIGN AND SETTING: Prospective controlled pilot study between May 2010 and May 2013 in a hospital intensive care unit. PATIENTS AND METHODS: HL-SAP patients chose conventional treatment alone (the control group) or conventional treatment combined with the experimental protocol (the HVHF&HP group) and were prospectively followed in our hospital...
September 2015: Annals of Saudi Medicine
https://www.readbyqxmd.com/read/26348469/different-clinical-presentations-of-hyperlipidemic-acute-pancreatitis-a-retrospective-study
#18
MULTICENTER STUDY
Guojian Yin, Xiaofeng Cang, Ge Yu, Guoyong Hu, Jianbo Ni, Jie Xiong, Yanling Hu, Miao Xing, Congying Chen, Yinshi Huang, Maochun Tang, Yan Zhao, Guilian Cheng, Rong Wan, Shaofeng Wang, Xingpeng Wang
OBJECTIVES: The goal of this study was to summarize the clinical features of hyperlipidemic acute pancreatitis (HLAP), and help clinicians understand the characteristic presentations of HLAP. METHODS: From July 2009 to June 2013, 1073 cases of acute pancreatitis were retrospectively assessed. The clinical characteristics of HLAP and non-HLAP were statistically analyzed. RESULTS: The etiologic ratio of HLAP in acute pancreatitis rose from 13% in 2009 to 25...
October 2015: Pancreas
https://www.readbyqxmd.com/read/26327761/distinctive-roles-of-unsaturated-and-saturated-fatty-acids-in-hyperlipidemic-pancreatitis
#19
Yu-Ting Chang, Ming-Chu Chang, Chien-Chih Tung, Shu-Chen Wei, Jau-Min Wong
AIM: To investigate how the saturated and unsaturated fatty acid composition influences the susceptibility of developing acute pancreatitis. METHODS: Primary pancreatic acinar cells were treated with low and high concentrations of different saturated and unsaturated fatty acids, and changes in the cytosolic Ca(2+) signal and the expression of protein kinase C (PKC) were measured after treatment. RESULTS: Unsaturated fatty acids at high concentrations, including oleic acid, linoleic acid, palmitoleic acid, docosahexaenoic acid, and arachidonic acid, induced a persistent rise in cytosolic Ca(2+) concentrations in acinar cells...
August 28, 2015: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/26269012/-the-clinical-experience-and-plasmapheresis-treatment-outcome-in-treatment-of-hyperlipidemia-acute-pancreatitis-among-uyghur
#20
Amutijiang Mahemuti, Abudoushalamu Abudoureyimu, Ge Chen
OBJECTIVE: To investigate the clinical features and plasmapheresis treatment outcome of hyperlipidemic acute pancreatitis among Uyghur population. METHODS: The clinical data of 41 cases (treatment group) diagnosed with acute hyperlipidemic pancreatitis and treated with plasmapheresis from August 2007 to August 2012 was studied, and treatment outcomes were statistically analyzed. Fifty patients during the same period who received medical treatment without plasmapheresis (control group) were collected, and were compared to the treatment group...
March 2015: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
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